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Russell E. Poland, Ph.D.

Concepts (543)

Concepts are derived automatically from a person's publications.
Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.
Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Hydrocortisone37201018381.830 Why?
Pituitary-Adrenal System2520105531.830 Why?
Depressive Disorder34201237151.450 Why?
Hypothalamo-Hypophyseal System1620107021.440 Why?
Antidepressive Agents, Second-Generation820134901.350 Why?
Sleep, REM1920135931.200 Why?
Citalopram420134020.990 Why?
Adrenocorticotropic Hormone2120056180.980 Why?
Prolactin2520056280.970 Why?
Corticosterone2820063010.960 Why?
Scopolamine72004920.830 Why?
Depressive Disorder, Major11201348100.810 Why?
Dexamethasone22202419620.800 Why?
N-Methyl-3,4-methylenedioxyamphetamine62003690.710 Why?
Bupropion420133030.680 Why?
Life Change Events420109560.670 Why?
Nicotine720066800.640 Why?
Desipramine620081820.620 Why?
Phencyclidine92005590.600 Why?
Antidepressive Agents7201229030.490 Why?
Hallucinogens520032120.450 Why?
Stress, Psychological8201145260.450 Why?
Prenatal Exposure Delayed Effects16200625370.440 Why?
Immobilization220042270.420 Why?
Massage12012840.400 Why?
Antidepressive Agents, Tricyclic420084270.400 Why?
Sleep15201348140.400 Why?
Muscarinic Antagonists320041350.380 Why?
Serotonin Plasma Membrane Transport Proteins120133260.370 Why?
Rats492008237170.350 Why?
Sepsis5202326040.350 Why?
Social Support2201121910.350 Why?
Nicotinic Agonists220062650.340 Why?
Electroencephalography12200962820.340 Why?
Social Environment3201010120.330 Why?
Cross Infection4202414270.330 Why?
Pneumonia, Ventilator-Associated220232790.320 Why?
Serotonin Agents22000290.320 Why?
Saliva920098520.310 Why?
Rats, Sprague-Dawley19200881080.310 Why?
Behavior, Animal5200818650.310 Why?
Fatigue Syndrome, Chronic220012170.310 Why?
Circadian Rhythm22201225900.300 Why?
Thyrotropin-Releasing Hormone619931390.300 Why?
Hypothalamic Diseases120091320.290 Why?
Radioimmunoassay1120088610.290 Why?
Haloperidol819923940.290 Why?
Mecamylamine22006270.290 Why?
Adrenergic Uptake Inhibitors220011860.290 Why?
Dextromethorphan32004370.290 Why?
Receptors, Opioid619891450.280 Why?
HIV Seropositivity120129620.280 Why?
Nicotinic Antagonists22006940.270 Why?
Urinary Tract Infections220248040.270 Why?
Digestive System Surgical Procedures220235840.270 Why?
Mixed Function Oxygenases320062650.270 Why?
Swimming220042120.260 Why?
Male12820243641540.260 Why?
Excitatory Amino Acid Antagonists220054510.260 Why?
Dose-Response Relationship, Drug192024107450.250 Why?
Thyrotropin919938340.250 Why?
Stress Disorders, Post-Traumatic4200946280.240 Why?
Depression6201282250.240 Why?
Allostasis12006760.240 Why?
Pituitary Hormones, Anterior51985570.240 Why?
Rats, Inbred Strains18199120780.240 Why?
Ganglionic Stimulants22003180.240 Why?
Serotonin Receptor Agonists219961510.230 Why?
Mexican Americans420121650.230 Why?
Dextrorphan1200440.230 Why?
Levorphanol1200490.230 Why?
Cues220068770.230 Why?
Adult8820242233050.230 Why?
Dopamine Uptake Inhibitors120052860.230 Why?
Iodophors1202370.220 Why?
Aryl Hydrocarbon Hydroxylases220062460.220 Why?
Stress, Physiological9200314070.220 Why?
Hospitalization102024108160.220 Why?
Mothers2200622080.220 Why?
Mupirocin12023550.220 Why?
Baths12023520.220 Why?
Cytochrome P-450 Enzyme System320014230.210 Why?
Interpersonal Relations1201114320.210 Why?
Self Mutilation21995570.210 Why?
Dopamine Agonists120053460.210 Why?
Female9720243965320.210 Why?
Polysomnography8201318680.210 Why?
Aspartic Acid320015750.200 Why?
Sleep Stages1120137050.200 Why?
Pituitary Gland, Anterior419891420.200 Why?
Mental Processes120032420.200 Why?
Chlorhexidine120231590.200 Why?
Medical Order Entry Systems220245230.200 Why?
Analysis of Variance10200662140.200 Why?
Growth Hormone1219915720.190 Why?
Catecholamines220023880.190 Why?
Sleep Deprivation320048480.190 Why?
Fludrocortisone12001240.190 Why?
Brain Chemistry519999510.190 Why?
Mineralocorticoids12001370.180 Why?
Humans13220247668120.180 Why?
Ethanol7200413260.180 Why?
Serotonin4200310450.180 Why?
Anti-Bacterial Agents4202474750.180 Why?
Adolescent Behavior1200911850.180 Why?
Coumarins120001190.170 Why?
Receptors, N-Methyl-D-Aspartate120059030.170 Why?
Smoking3200990770.170 Why?
Buspirone12000800.170 Why?
Mydriatics11999670.160 Why?
Psychiatric Status Rating Scales13200460200.160 Why?
Amitriptyline219911100.160 Why?
Middle Aged5120242232670.160 Why?
Vital Signs120201440.160 Why?
Genotype32013130360.160 Why?
Methicillin-Resistant Staphylococcus aureus220237050.160 Why?
Neuroprotective Agents120059560.160 Why?
Catheter-Related Infections120222790.160 Why?
Dibenzocycloheptenes21989270.160 Why?
Substance Withdrawal Syndrome220236270.160 Why?
Buprenorphine220236670.160 Why?
Dizocilpine Maleate319951710.150 Why?
Arousal4201011740.150 Why?
8-Hydroxy-2-(di-n-propylamino)tetralin21996320.150 Why?
Substance-Related Disorders3200944210.150 Why?
Morpholines120015840.150 Why?
Hypotension, Orthostatic120012580.150 Why?
Magnetic Resonance Spectroscopy5200136810.150 Why?
Survivors2200623790.150 Why?
Influenza A Virus, H1N1 Subtype120214530.140 Why?
Myotonic Dystrophy11998770.140 Why?
Interleukin-62200632260.140 Why?
Fenfluramine11997580.140 Why?
Psychomotor Performance2200318850.140 Why?
Carbapenems120181250.140 Why?
Trinucleotide Repeats119982570.140 Why?
Receptors, sigma31994460.140 Why?
Cytochrome P-450 CYP2D6320011080.140 Why?
Hydroxychloroquine120214270.130 Why?
Multiple Organ Failure120193890.130 Why?
Product Surveillance, Postmarketing120214630.130 Why?
Hospitals, Community320243630.130 Why?
Gene Deletion1200426690.130 Why?
Reaction Time4200220850.130 Why?
Hospitals7202338850.130 Why?
Adolescent232021889020.130 Why?
Metalloporphyrins12016410.130 Why?
Receptors, Cholinergic119972430.130 Why?
Hyperbilirubinemia, Neonatal12016300.130 Why?
Anti-Infective Agents120239870.130 Why?
Naloxone319893720.130 Why?
Animals5420081689390.130 Why?
United States Food and Drug Administration2202116730.130 Why?
Awards and Prizes120203650.130 Why?
Heme Oxygenase (Decyclizing)120161650.120 Why?
Testosterone10200324950.120 Why?
Tomography, Emission-Computed, Single-Photon2200011430.120 Why?
Brain142004271580.120 Why?
Endocrine Glands219871010.120 Why?
Pemoline11995180.120 Why?
Phenelzine11995280.120 Why?
United States202024729450.120 Why?
Bacteremia120229870.120 Why?
Receptors, Neurotransmitter419901710.120 Why?
Cross-Over Studies5201321050.120 Why?
Imipramine22000960.120 Why?
Anti-Anxiety Agents219974040.120 Why?
Staphylococcal Infections1202313960.120 Why?
Disease Outbreaks1202417610.120 Why?
Anti-Inflammatory Agents2200618050.110 Why?
Norepinephrine420068980.110 Why?
Bilirubin120164400.110 Why?
Blood Transfusion1202113080.110 Why?
Medicare2202368130.110 Why?
Luteinizing Hormone1119898280.110 Why?
Conditioning, Operant220063060.110 Why?
Age Factors102020183970.110 Why?
Epinephrine320067820.110 Why?
Sexual Maturation119952560.110 Why?
Therapeutic Touch1201290.110 Why?
Electronic Health Records5202448800.100 Why?
Proton Pump Inhibitors120185500.100 Why?
Extinction, Psychological220063670.100 Why?
Hyperglycemia1202113890.100 Why?
Pneumonia1202421610.100 Why?
Hippocampus3200337760.100 Why?
Frontal Lobe1199914080.100 Why?
Piperazines2199525470.100 Why?
Double-Blind Method82013124300.100 Why?
Respiratory Insufficiency1202112410.100 Why?
Self Administration420063860.100 Why?
Aged2920241713440.100 Why?
Postpartum Period1199911950.100 Why?
Cross-Cultural Comparison420126360.090 Why?
Nialamide1199150.090 Why?
Morphine519866580.090 Why?
Suicide, Attempted1202014130.090 Why?
Clostridium Infections120185630.090 Why?
3,4-Methylenedioxyamphetamine1199020.090 Why?
Benzodiazepines2199711370.090 Why?
Cocaine420059440.090 Why?
Gene Frequency4201336240.090 Why?
Neuropsychological Tests1200371190.090 Why?
Tetrahydronaphthalenes11990850.090 Why?
Cerebrovascular Circulation2200026710.090 Why?
Injections, Subcutaneous519946840.090 Why?
Influenza, Human1202115430.090 Why?
Serotonin Antagonists119901460.090 Why?
Hospital Mortality5202253440.090 Why?
Deamino Arginine Vasopressin11990870.090 Why?
Aged, 80 and over102024595480.080 Why?
Drug Resistance, Multiple, Bacterial220245920.080 Why?
Inositol319992150.080 Why?
Quality Indicators, Health Care1201918040.080 Why?
Mental Disorders4199968690.080 Why?
Somatoform Disorders120124250.080 Why?
Phencyclidine Abuse1198880.080 Why?
Electromyography3200413980.080 Why?
Pregnancy202006302360.080 Why?
Choline319995110.080 Why?
Saccharin21987200.070 Why?
Alprazolam119881030.070 Why?
Opioid-Related Disorders1202321880.070 Why?
Drug Interactions5200014190.070 Why?
Leukemia Inhibitory Factor22006810.070 Why?
Risk Factors92021748890.070 Why?
Hydroxymethylglutaryl-CoA Reductase Inhibitors1202232500.070 Why?
Retrospective Studies112023816570.070 Why?
Codeine11987520.070 Why?
Drug Administration Schedule3201148530.070 Why?
Blood Glucose1202164220.070 Why?
Receptors, Phencyclidine41990130.070 Why?
Receptors, Nicotinic220034940.070 Why?
Inpatients3202425660.070 Why?
Psychology120083530.070 Why?
Prisoners119903150.070 Why?
Infant, Premature1201621200.070 Why?
Placebos2200516590.060 Why?
Morphinans11985270.060 Why?
Reference Values5199949140.060 Why?
Mental Health1202032690.060 Why?
Lithium219885990.060 Why?
Schizophrenic Psychology2199216470.060 Why?
Corticotropin-Releasing Hormone220063620.060 Why?
Phenazocine3199470.060 Why?
Neoplasms22006223500.060 Why?
Azocines11985200.060 Why?
Anticoagulants1200048540.060 Why?
Dehydroepiandrosterone120062490.060 Why?
Animals, Newborn4198626770.060 Why?
Severity of Illness Index32012159120.060 Why?
Minority Groups1201212080.060 Why?
Family Health1200912540.060 Why?
Schizophrenia5199269760.060 Why?
Disease Models, Animal62005183290.060 Why?
Binding, Competitive1200511410.060 Why?
Food Preferences219873970.060 Why?
ROC Curve2199036210.060 Why?
Chronic Disease2201093580.060 Why?
Recurrence3201085070.060 Why?
Narcotic Antagonists219895910.060 Why?
Association Learning120052190.060 Why?
Aging3199987280.060 Why?
Antipsychotic Agents3199530780.050 Why?
Demography1200816410.050 Why?
Polymorphism, Genetic3200642490.050 Why?
Adjustment Disorders11983680.050 Why?
Exploratory Behavior120042710.050 Why?
Diabetes Mellitus1202158880.050 Why?
Surgical Wound Infection2202315470.050 Why?
Physical Stimulation120045140.050 Why?
Causality1200912520.050 Why?
Intelligence Tests120035040.050 Why?
Fatty Acids, Omega-31201213990.050 Why?
Maze Learning120044790.050 Why?
Pandemics4202487340.050 Why?
Time Factors72013401490.050 Why?
Azetidines120031510.050 Why?
Psychotropic Drugs519918800.050 Why?
Administration, Intranasal120234820.050 Why?
Electronics120233150.050 Why?
Endotoxins120045190.050 Why?
Pneumonia, Bacterial120243190.050 Why?
Genetics, Population120069430.050 Why?
Anti-Infective Agents, Local120232460.050 Why?
Extracellular Space120035630.050 Why?
Cytochrome P-450 CYP3A120011170.050 Why?
Anxiety Disorders3200927430.040 Why?
Virginia120201150.040 Why?
Alcoholic Intoxication119821710.040 Why?
Oxygen2202442520.040 Why?
Nervous System119845420.040 Why?
Technetium Tc 99m Exametazime12000610.040 Why?
Military Personnel1199012600.040 Why?
Delayed-Action Preparations120049660.040 Why?
Cyclohexanols120001260.040 Why?
Memory1199021920.040 Why?
Creatine219994240.040 Why?
Area Under Curve2200116390.040 Why?
Tobacco Use Disorder120057080.040 Why?
Azithromycin120212010.040 Why?
Anticonvulsants1198919210.040 Why?
Intensive Care Units2202337990.040 Why?
California2200114350.040 Why?
Biological Assay219946260.040 Why?
Glucocorticoids2202421580.040 Why?
Pituitary Hormones119801820.040 Why?
Dietary Supplements1201234290.040 Why?
Antiviral Agents2202130700.040 Why?
Child82023806700.040 Why?
Adrenal Glands319895560.040 Why?
Behavior, Addictive120044290.040 Why?
Intelligence120039250.040 Why?
Disease Progression22021136420.040 Why?
Opiate Substitution Treatment120234520.040 Why?
Hormones319968660.040 Why?
Cytochrome P-450 CYP2E111998410.040 Why?
Alkaloids119991920.040 Why?
Cholesterol2200629040.040 Why?
Sample Size120018440.040 Why?
Odds Ratio2202196610.040 Why?
Narcotics120003320.040 Why?
Motor Activity2200627110.040 Why?
Administration, Oral2200040190.040 Why?
Computers120205890.040 Why?
Sex Factors62004106190.040 Why?
Alcohol Dehydrogenase119981130.040 Why?
Follicle Stimulating Hormone519897310.040 Why?
Aldehyde Dehydrogenase119981460.030 Why?
Hydroxyindoleacetic Acid11996940.030 Why?
Observation119993100.030 Why?
Wakefulness1200412820.030 Why?
Follow-Up Studies42009393120.030 Why?
Binding Sites1200560130.030 Why?
Polymorphism, Restriction Fragment Length119987660.030 Why?
Infection Control120249840.030 Why?
Pilot Projects2202187280.030 Why?
Secretory Rate21986820.030 Why?
Magnetic Resonance Imaging32001365700.030 Why?
Creatinine2200119170.030 Why?
Panic219851030.030 Why?
Blood Proteins1200111940.030 Why?
Case-Control Studies32003222480.030 Why?
Motivation1200520200.030 Why?
Staphylococcus aureus1202314290.030 Why?
Cyclazocine21985100.030 Why?
Ethylketocyclazocine2198540.030 Why?
Protons2199811010.030 Why?
Treatment Outcome32012652860.030 Why?
Databases, Factual2202180650.030 Why?
Gonadotropin-Releasing Hormone3199011420.030 Why?
Young Adult52021599390.030 Why?
International Classification of Diseases120219350.030 Why?
Dioxolanes11994230.030 Why?
Sympathomimetics11994560.030 Why?
Cortisone11995900.030 Why?
Length of Stay2202464910.030 Why?
Communicable Disease Control120218570.030 Why?
Depression, Chemical119941860.030 Why?
Longitudinal Studies22010147620.030 Why?
Comorbidity12009105800.030 Why?
Language1200315500.030 Why?
Alcohol Drinking2200440450.030 Why?
Bites and Stings11995940.030 Why?
Alleles3200168960.030 Why?
Benzodiazepinones11973500.030 Why?
Stereoisomerism119946120.030 Why?
Injections, Intravenous2200313770.030 Why?
Evaluation Studies as Topic1199616220.030 Why?
Isoenzymes1199816880.030 Why?
Patient Admission1202013640.030 Why?
Predictive Value of Tests22021154250.030 Why?
Vanilmandelic Acid11972170.030 Why?
17-Hydroxycorticosteroids11972380.030 Why?
Phototherapy120163680.030 Why?
Colon1202117970.030 Why?
Pregnancy Complications3199929710.030 Why?
Lesch-Nyhan Syndrome11991160.020 Why?
Hypothalamus1199710030.020 Why?
Aggression119967480.020 Why?
Blood Pressure2200685330.020 Why?
Drug Synergism1199617570.020 Why?
Pharmacogenetics119966820.020 Why?
Pyridines1200328880.020 Why?
Infant22021364590.020 Why?
Institutionalization119911080.020 Why?
Neonatal Screening120166190.020 Why?
Compulsive Behavior119911170.020 Why?
Thyroxine219876650.020 Why?
Child, Preschool22021425770.020 Why?
Injections, Intraperitoneal119914110.020 Why?
Personality Tests11990800.020 Why?
MMPI11990800.020 Why?
Radiopharmaceuticals1200027030.020 Why?
Suicidal Ideation1202014670.020 Why?
Patient Discharge1202334660.020 Why?
Cohort Studies22023417060.020 Why?
Psychotic Disorders1198532750.020 Why?
Respiration, Artificial1202127270.020 Why?
Organ Size2198722620.020 Why?
Psychopharmacology119911460.020 Why?
Scotland119891420.020 Why?
Brain Diseases1199815520.020 Why?
Protein Binding1200193260.020 Why?
Injections, Intraventricular119892270.020 Why?
Health Policy1202126970.020 Why?
Mice, Knockout12004144730.020 Why?
Receptors, Muscarinic119891560.020 Why?
Body Weight5199646260.020 Why?
Central Nervous System1199613450.020 Why?
Stimulation, Chemical219863050.020 Why?
Cushing Syndrome119902410.020 Why?
Body Mass Index12006130500.020 Why?
Adaptation, Physiological1199513120.020 Why?
Pineal Gland119891580.020 Why?
Electroshock219861200.020 Why?
Cardiovascular Diseases12013156520.020 Why?
Analgesics1199410680.020 Why?
Prospective Studies32010548720.020 Why?
Indians, North American119913540.020 Why?
Survival Rate12021128260.020 Why?
Alcoholism1199819800.020 Why?
Iran119907620.020 Why?
Analgesics, Opioid1202338370.020 Why?
Piperidines1199416630.020 Why?
Osmolar Concentration119876550.020 Why?
Los Angeles120062440.020 Why?
Chromatography, High Pressure Liquid2200315290.020 Why?
Logistic Models12020132760.020 Why?
Reinforcement Schedule120051230.020 Why?
Heart Rate2201342070.020 Why?
Mice, Inbred C57BL12004223510.020 Why?
Hypnotics and Sedatives1197311930.020 Why?
Triiodothyronine119874930.020 Why?
Clonidine119861700.020 Why?
Endorphins21986730.010 Why?
Vasopressins219783580.010 Why?
Thyroid Gland2198911700.010 Why?
Disorders of Sex Development119861290.010 Why?
Prevalence12022158350.010 Why?
Incidence12023215270.010 Why?
Antibodies, Monoclonal1202192440.010 Why?
Delivery of Health Care1202253670.010 Why?
Sexual Dysfunctions, Psychological119861930.010 Why?
Propranolol119864930.010 Why?
Melatonin119896700.010 Why?
Electrochemistry120031440.010 Why?
Microdialysis120031560.010 Why?
Antitussive Agents12001190.010 Why?
Chromatography, Gas119811500.010 Why?
Drug Therapy, Combination1201263060.010 Why?
Bipolar Disorder3199051300.010 Why?
Sex Characteristics2199526450.010 Why?
Submandibular Gland11981850.010 Why?
Estradiol1198919470.010 Why?
Risk1201396020.010 Why?
Hypothermia119831890.010 Why?
Mice32006818980.010 Why?
Cerebral Cortex1199757530.010 Why?
Phenotype32006167220.010 Why?
Family1199132090.010 Why?
Heart1201344250.010 Why?
Gene Duplication120013150.010 Why?
Electrocardiography1201364080.010 Why?
Eating1198715390.010 Why?
Algorithms12020140730.010 Why?
Molecular Weight1200121680.010 Why?
Ion Exchange Resins1197880.010 Why?
Analgesia119844610.010 Why?
Anion Exchange Resins11978100.010 Why?
Trichloroacetic Acid11978480.010 Why?
Cross-Sectional Studies12020263090.010 Why?
China1198523860.010 Why?
Epidermal Growth Factor119816970.010 Why?
Talc11978480.010 Why?
Nerve Growth Factors119815640.010 Why?
Asia219916290.010 Why?
Regression Analysis1198863290.010 Why?
Half-Life119996480.010 Why?
Peptides2198143470.010 Why?
Pituitary Gland219876350.010 Why?
Methadone119803170.010 Why?
Enzyme Induction119984550.010 Why?
Social Dominance11996390.010 Why?
Anxiety1201246680.010 Why?
Water-Electrolyte Balance119783260.010 Why?
Fear1198514960.010 Why?
Affective Symptoms119994180.010 Why?
Psychological Tests219896420.010 Why?
Ligands1200332740.010 Why?
Infant, Newborn12016263870.010 Why?
Gonadotropins, Pituitary11975700.010 Why?
Telemetry119962010.010 Why?
Rabbits1198147520.010 Why?
Infusions, Intravenous1200022280.010 Why?
Body Water119963370.010 Why?
Kidney1199070730.010 Why?
Patient Readmission1198932830.010 Why?
Flurazepam1197380.010 Why?
Genetic Variation1200966130.010 Why?
Diffusion119958080.010 Why?
Models, Statistical1198850920.010 Why?
Gene Expression1200675850.010 Why?
Aldosterone119788810.010 Why?
Glutamine119965750.010 Why?
Body Temperature119967800.010 Why?
Diagnosis, Differential21990129850.010 Why?
Glycols11970540.010 Why?
RNA, Messenger12006127950.010 Why?
Glutamic Acid1199611810.010 Why?
Macaca mulatta1199623410.010 Why?
Aerospace Medicine11970950.010 Why?
Periodicity119913470.010 Why?
Statistics as Topic1197623500.010 Why?
Basal Ganglia Diseases119891450.000 Why?
Emigration and Immigration119914050.000 Why?
DNA1200172100.000 Why?
Drug Tolerance119893650.000 Why?
Professional-Family Relations119915000.000 Why?
Suicide1199716060.000 Why?
Kinetics2198662880.000 Why?
Thyroid Hormones119894080.000 Why?
Agoraphobia119851770.000 Why?
Uric Acid119718090.000 Why?
Personality Inventory1198710190.000 Why?
Sodium2197815940.000 Why?
Pharmaceutical Vehicles11980560.000 Why?
Synaptic Transmission1198611750.000 Why?
Caregivers1199123030.000 Why?
Chemical Precipitation119781740.000 Why?
Adsorption119781980.000 Why?
Isotope Labeling119783900.000 Why?
Ambulatory Care1198727790.000 Why?
Learning1198617540.000 Why?
Clinical Trials as Topic1197280450.000 Why?
Genetic Predisposition to Disease11998180760.000 Why?
Drug Evaluation, Preclinical1198013310.000 Why?
Iodine Radioisotopes1197810300.000 Why?
Naval Medicine11971300.000 Why?
Diving11971430.000 Why?
Pain1198650980.000 Why?
Sampling Studies119716140.000 Why?
Tomography, X-Ray Computed11990207100.000 Why?
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.