Harvard Catalyst Profiles

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Eric Sebastian Fischer, Ph.D.

Concepts (351)

Concepts are derived automatically from a person's publications.
Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.
Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Ubiquitin-Protein Ligases31202418873.610 Why?
Thalidomide1220248841.920 Why?
Ubiquitination18202410061.700 Why?
Peptide Hydrolases720186221.430 Why?
Cryoelectron Microscopy720246421.240 Why?
Small Molecule Libraries820217241.080 Why?
Ikaros Transcription Factor720222311.040 Why?
Transcription Factors172024120941.020 Why?
Protein Phosphatase 2220242350.950 Why?
Inhibitor of Apoptosis Proteins120231970.800 Why?
Proteasome Endopeptidase Complex4202413120.760 Why?
Apoptosis Regulatory Proteins2202311340.730 Why?
Substrate Specificity9202417920.730 Why?
Adaptor Proteins, Signal Transducing13202228950.720 Why?
Caspases120238760.680 Why?
Protein Kinase Inhibitors14202356290.630 Why?
Structure-Activity Relationship9202430690.620 Why?
Drug Design4202110490.620 Why?
Cell Cycle Proteins5202434420.610 Why?
Proteomics9202438160.610 Why?
Proteins5202460260.610 Why?
Crystallography, X-Ray11202419740.600 Why?
Duane Retraction Syndrome12018590.590 Why?
Polymerization320241570.590 Why?
Ubiquitin520248370.590 Why?
Chromatin5202429380.580 Why?
Drug Discovery4202410440.560 Why?
Mitochondrial Proteins120239770.560 Why?
Histone Deacetylases120217180.550 Why?
Acetamides120182550.540 Why?
Proteome3202218550.490 Why?
Polymers1202216160.480 Why?
Immunologic Factors2202215850.470 Why?
Protein Binding13202493110.470 Why?
HEK293 Cells7202442570.450 Why?
Tumor Suppressor Proteins4202428000.450 Why?
Thiophenes120185690.450 Why?
Protein Kinases1202016100.440 Why?
Sulfonamides2202019730.430 Why?
Models, Molecular10202154100.430 Why?
Intracellular Signaling Peptides and Proteins3201928720.430 Why?
Molecular Structure6202418660.420 Why?
Dengue Virus220242000.410 Why?
Multiprotein Complexes5202411200.410 Why?
Nuclear Proteins5202457860.400 Why?
Myeloid-Lymphoid Leukemia Protein220243000.390 Why?
Peptide Termination Factors22022560.380 Why?
Von Hippel-Lindau Tumor Suppressor Protein320243050.380 Why?
Indoles1201918280.380 Why?
Cell Line92024155910.370 Why?
Binding Sites9202460360.370 Why?
Apoptosis7202494680.360 Why?
Antibodies, Viral4202331420.360 Why?
DNA-Binding Proteins7202195740.350 Why?
Biocatalysis320231700.350 Why?
Protein Multimerization320249790.350 Why?
Cell Line, Tumor252024168860.350 Why?
Ligands8202332580.350 Why?
Lymphoma, T-Cell220233040.350 Why?
Drug Resistance, Neoplasm8202352490.340 Why?
Cyclins220235930.340 Why?
Antineoplastic Agents132024135910.330 Why?
Casein Kinase Ialpha22021260.330 Why?
Methyltransferases220233740.330 Why?
Catalytic Domain520247050.320 Why?
Zinc Fingers220245680.320 Why?
Fluorescence Resonance Energy Transfer220234180.320 Why?
T-Lymphocytes, Regulatory1202130710.290 Why?
Humans8120247584060.290 Why?
Kinetics5202163710.280 Why?
Phthalimides22024340.270 Why?
Cyclin-Dependent Kinase 6220193450.260 Why?
Amino Acid Motifs220199290.260 Why?
Multiple Myeloma5202251290.250 Why?
Neoplasms62024220320.240 Why?
Flavivirus12024220.240 Why?
Leukemia2202315190.230 Why?
Leukemia, Myeloid, Acute4202435990.230 Why?
Piperidones12024370.230 Why?
Methylation2202410800.230 Why?
Viral Envelope Proteins220246380.230 Why?
Biotinylation120241840.220 Why?
Enzyme Activation3202335930.220 Why?
RNA, Transfer220232890.220 Why?
Cell Nucleus3202329070.220 Why?
Dibenzazepines12022260.220 Why?
Piperazines4202125110.210 Why?
Cell Proliferation112024104160.210 Why?
Directed Molecular Evolution120241580.210 Why?
Nucleocapsid12023630.210 Why?
RNA Processing, Post-Transcriptional220234140.210 Why?
Cytokine Receptor Common beta Subunit12022220.210 Why?
Mitogen-Activated Protein Kinase 712022660.210 Why?
Cyclic Nucleotide Phosphodiesterases, Type 612021270.200 Why?
Animals2220241677680.200 Why?
Cyclin-Dependent Kinase Inhibitor Proteins12021530.200 Why?
Cyclin-Dependent Kinase 922021670.190 Why?
DNA Damage5201924390.190 Why?
Carrier Proteins4202349380.190 Why?
tRNA Methyltransferases12021520.190 Why?
Immunoglobulin G3202245400.190 Why?
Antiviral Agents3202430560.190 Why?
Chimera120224520.190 Why?
Methanol12021910.190 Why?
Proto-Oncogene Protein c-fli-1120211040.190 Why?
Morpholines120245800.180 Why?
Mutation82024299150.180 Why?
Phosphodiesterase Inhibitors120212130.180 Why?
Pyrrolidines120223370.180 Why?
Molecular Conformation220195430.180 Why?
Protein Tyrosine Phosphatase, Non-Receptor Type 11120212230.180 Why?
Oncogenes2202312200.180 Why?
Indoleacetic Acids12020440.180 Why?
Eukaryotic Initiation Factor-4E120211120.180 Why?
Virus Internalization120244940.180 Why?
Pyridines3202128590.180 Why?
Eukaryota120211000.180 Why?
Proto-Oncogene Proteins c-bcl-6120201910.180 Why?
Histone-Lysine N-Methyltransferase120246770.170 Why?
Receptor, Fibroblast Growth Factor, Type 1120212560.170 Why?
Receptor, Fibroblast Growth Factor, Type 2120212110.170 Why?
Oncogene Proteins220217190.170 Why?
Cyclin-Dependent Kinase 2120201830.170 Why?
Dose-Response Relationship, Drug32024107480.170 Why?
RNA-Binding Protein EWS120212100.170 Why?
Spodoptera120191410.170 Why?
NF-E2-Related Factor 2120223740.170 Why?
Cyclin-Dependent Kinase 5120201120.170 Why?
Jurkat Cells120217350.170 Why?
Cross Reactions120218180.170 Why?
HCT116 Cells220174020.170 Why?
Mitogen-Activated Protein Kinases1202412450.160 Why?
Lower Extremity Deformities, Congenital12018120.160 Why?
Inflammasomes120245270.160 Why?
Databases, Protein120203870.160 Why?
Upper Extremity Deformities, Congenital12018320.150 Why?
Cyclin-Dependent Kinase 4220195550.150 Why?
GTP-Binding Proteins120239500.150 Why?
Nuclear Magnetic Resonance, Biomolecular120215090.150 Why?
Lysine120229980.150 Why?
Teratogens120181170.150 Why?
Immunologic Surveillance12018920.150 Why?
Viral Nonstructural Proteins120192230.150 Why?
Mice152024811010.150 Why?
Phosphorylation7202382970.150 Why?
Xenopus120197170.150 Why?
Cullin Proteins320161780.140 Why?
Species Specificity2201824170.140 Why?
Immunity, Humoral120216040.140 Why?
Mammals1202211320.140 Why?
Pyrimidinones120193830.140 Why?
Leukocytes, Mononuclear1202418260.140 Why?
Purines120206050.140 Why?
Lymphoma, B-Cell120239350.140 Why?
Oncogene Proteins, Fusion2202315940.140 Why?
Isoenzymes1202116860.140 Why?
Protein Structure, Secondary1201912290.140 Why?
Tubulin120206920.130 Why?
Histone Deacetylase Inhibitors120217720.130 Why?
Nucleotidyltransferases120182430.130 Why?
Biphenyl Compounds120219880.130 Why?
Lymphoma, Mantle-Cell120182370.130 Why?
Signal Transduction82023233420.130 Why?
Frontotemporal Dementia120192460.130 Why?
Protein Interaction Mapping120196160.130 Why?
Protease Inhibitors120197540.130 Why?
Acrylamides120172590.130 Why?
Pyrazines1202111980.130 Why?
Pyrimidines4202130060.130 Why?
Heart Septal Defects, Atrial120184600.120 Why?
Tauopathies120193170.120 Why?
Ubiquitins320233660.120 Why?
Proto-Oncogene Proteins c-akt2202424430.120 Why?
Autophagy1202313220.120 Why?
Quinazolines2202113600.120 Why?
Cell Survival3202157810.120 Why?
Lysosomes120209190.120 Why?
Principal Component Analysis120179400.120 Why?
Drug Resistance, Viral120198600.120 Why?
Proto-Oncogene Proteins2202444850.110 Why?
fms-Like Tyrosine Kinase 3120174950.110 Why?
Benzamides1201913680.110 Why?
Stress, Physiological1202113980.110 Why?
Receptors, G-Protein-Coupled1202112450.110 Why?
GTP Phosphohydrolases120165170.100 Why?
Waldenstrom Macroglobulinemia1202110670.100 Why?
Focal Adhesion Protein-Tyrosine Kinases220231860.100 Why?
Neuroprotective Agents120199550.100 Why?
Xeroderma Pigmentosum Group A Protein12011130.100 Why?
Pyrazoles2201919880.100 Why?
ras Proteins1201710490.100 Why?
Guanine Nucleotide Exchange Factors120165680.100 Why?
Hormones120168690.100 Why?
Proto-Oncogene Proteins p21(ras)1201917250.100 Why?
Embryonic Stem Cells1201812620.090 Why?
Abnormalities, Multiple1201814140.090 Why?
RNA-Binding Proteins1201918940.090 Why?
Protein-Tyrosine Kinases1201924160.090 Why?
Ultraviolet Rays2201510760.090 Why?
Protein Stability220225660.090 Why?
Mass Spectrometry1201721890.090 Why?
Enzyme Inhibitors1202037090.090 Why?
Endothelial Cells1202235330.080 Why?
Gene Deletion1201726660.080 Why?
Bone Neoplasms1202125310.080 Why?
RNA, Messenger22021127590.080 Why?
Nerve Tissue Proteins1202144060.080 Why?
DNA Repair2202320380.080 Why?
tau Proteins1201920850.080 Why?
Lung Neoplasms32023132450.070 Why?
Myelodysplastic Syndromes1201713920.070 Why?
Allosteric Regulation220204260.070 Why?
Mice, SCID2202426260.070 Why?
Amino Acid Sequence12018134470.070 Why?
Gene Expression Regulation12024118920.070 Why?
Protein Structure, Tertiary3201837960.060 Why?
Breast Neoplasms22024210170.060 Why?
Pandemics2202286110.060 Why?
Homeodomain Proteins1201424130.060 Why?
Cells, Cultured12020189400.060 Why?
Mutagenesis, Site-Directed2201816930.060 Why?
DNA1201871990.060 Why?
Culicidae120241080.060 Why?
Mitogens120242300.060 Why?
Xenograft Model Antitumor Assays2202435740.060 Why?
Co-Repressor Proteins120231910.050 Why?
Azepines120243290.050 Why?
Protein Conformation2202239660.050 Why?
Allosteric Site120221030.050 Why?
JNK Mitogen-Activated Protein Kinases120244410.050 Why?
Tumor Cells, Cultured2202161270.050 Why?
Coronavirus OC43, Human12021180.050 Why?
Interleukin-5120222690.050 Why?
Female920243903230.050 Why?
Guanosine12021480.050 Why?
Heart Defects, Congenital1201846730.050 Why?
Genes, Overlapping12021360.050 Why?
Interleukin-3120224250.050 Why?
Immunologic Tests120211030.050 Why?
Mitogen-Activated Protein Kinase Kinases120246400.050 Why?
Trans-Activators2202128600.050 Why?
p38 Mitogen-Activated Protein Kinases120246850.050 Why?
Erythroid Cells120222350.050 Why?
Phenotype12018165340.040 Why?
Phenothiazines12020610.040 Why?
Dipeptides120223860.040 Why?
Hydrogen Bonding120202900.040 Why?
Enzyme Activators12020570.040 Why?
Reproducibility of Results12018200550.040 Why?
Asymptomatic Infections120211310.040 Why?
Young Adult32021588080.040 Why?
Recombinant Proteins2202165200.040 Why?
Benzylamines120212470.040 Why?
Immunoglobulin Class Switching120212890.040 Why?
Neurons1201994160.040 Why?
Imides12019150.040 Why?
Solvents120202920.040 Why?
Models, Immunological120215130.040 Why?
Adolescent32022878920.040 Why?
Prodrugs120212590.040 Why?
Granulocyte-Macrophage Colony-Stimulating Factor120228860.040 Why?
Triazoles120249020.040 Why?
G1 Phase120204030.040 Why?
Receptors, Cytoplasmic and Nuclear120238550.040 Why?
Asymptomatic Diseases120215840.040 Why?
Aminopyridines120225640.040 Why?
Synthetic Biology120201850.040 Why?
Serine120228280.040 Why?
Gene Knockout Techniques120218020.040 Why?
Cytoplasm1202215140.040 Why?
Genome, Human1201144160.040 Why?
Interleukin-1beta120249960.040 Why?
Protein Transport1202419630.040 Why?
Phenylurea Compounds120215290.040 Why?
Receptors, Fc120215340.040 Why?
Benzofurans120181400.040 Why?
Nucleotides, Cyclic12018840.040 Why?
Drug Screening Assays, Antitumor120207140.040 Why?
Gene Expression2202275830.040 Why?
Ubiquitin-Conjugating Enzymes120181980.040 Why?
Immunoglobulin A120219790.040 Why?
Transcriptional Activation1202317520.040 Why?
Carrier State120215250.040 Why?
Phthalazines120193820.040 Why?
Cell Death1202216680.030 Why?
Inhibitory Concentration 50120174620.030 Why?
Cyclin-Dependent Kinases120206550.030 Why?
Immunity, Cellular1202215570.030 Why?
Protein Subunits120209420.030 Why?
Apoproteins12016450.030 Why?
Oxazoles120171990.030 Why?
Protein Engineering120205410.030 Why?
Immunocompromised Host120218560.030 Why?
Microfilament Proteins1202111330.030 Why?
Systemic Inflammatory Response Syndrome120216210.030 Why?
Receptor Protein-Tyrosine Kinases1202316130.030 Why?
Interleukin-21202218880.030 Why?
Sulfones120184460.030 Why?
Precursor Cell Lymphoblastic Leukemia-Lymphoma1202415470.030 Why?
Chemotaxis120185980.030 Why?
Intercellular Signaling Peptides and Proteins1202216510.030 Why?
Immunity120219980.030 Why?
Basic Helix-Loop-Helix Transcription Factors1202111360.030 Why?
Amides120174470.030 Why?
Protein Processing, Post-Translational1202319720.030 Why?
Gene Knockdown Techniques1201916100.030 Why?
Molecular Dynamics Simulation120174320.030 Why?
Mice, Inbred NOD1201818250.030 Why?
Receptors, Antigen, T-Cell1202325320.030 Why?
Age of Onset1202132980.030 Why?
Oligopeptides1201911850.030 Why?
Adenine120189750.030 Why?
Cell Division1202044580.030 Why?
Hepacivirus1201913330.030 Why?
Vibrio cholerae120187930.020 Why?
Male420243587470.020 Why?
Repressor Proteins1202229800.020 Why?
Antibodies, Neutralizing1202119310.020 Why?
Survivors1202123700.020 Why?
Thiazoles1201715100.020 Why?
MAP Kinase Signaling System1201714770.020 Why?
Piperidines1201816390.020 Why?
Gene Regulatory Networks1201817400.020 Why?
Hematopoietic Stem Cells1202233840.020 Why?
Molecular Targeted Therapy1202127960.020 Why?
Middle Aged220212195680.020 Why?
Risk1202195990.020 Why?
Adult220212199350.020 Why?
DNA Repair Enzymes120113440.020 Why?
Hepatitis C1201915790.020 Why?
Macrophages1202457370.020 Why?
Cohort Studies22021412560.020 Why?
Models, Theoretical1201935610.020 Why?
Immunotherapy1202146410.020 Why?
T-Lymphocytes12023101710.020 Why?
Genomics1202157900.020 Why?
Gene Expression Regulation, Neoplastic1202185060.010 Why?
Disease Progression12021134680.010 Why?
Disease Models, Animal12023181190.010 Why?
Ovarian Neoplasms1202048760.010 Why?
Severity of Illness Index12021157850.010 Why?
Inflammation12022107180.010 Why?
Genome-Wide Association Study12021126040.010 Why?
Models, Genetic1201134410.010 Why?
Infant, Newborn12021261830.010 Why?
Carcinoma, Non-Small-Cell Lung1201852460.010 Why?
Infant12021360550.010 Why?
Child, Preschool12021420620.010 Why?
Prospective Studies12021541370.010 Why?
Child12021798180.010 Why?
Aged120211682180.000 Why?
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Concepts (351)
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Co-Authors (143)
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.