Harvard Catalyst Profiles

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Eric Sebastian Fischer, Ph.D.

Concepts (341)

Concepts are derived automatically from a person's publications.
Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.
Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Ubiquitin-Protein Ligases28202418613.110 Why?
Thalidomide1220248902.010 Why?
Peptide Hydrolases720186341.470 Why?
Small Molecule Libraries820217201.110 Why?
Ikaros Transcription Factor720222171.110 Why?
Transcription Factors162024122080.940 Why?
Ubiquitination16202410120.910 Why?
Inhibitor of Apoptosis Proteins120232150.820 Why?
Apoptosis Regulatory Proteins2202311570.760 Why?
Adaptor Proteins, Signal Transducing13202229160.740 Why?
Substrate Specificity8202318010.710 Why?
Caspases120239280.700 Why?
Proteomics9202436380.650 Why?
Protein Kinase Inhibitors13202355350.640 Why?
Drug Design4202110760.630 Why?
Drug Discovery3202110580.620 Why?
Duane Retraction Syndrome12018600.620 Why?
Structure-Activity Relationship8202331290.600 Why?
Cryoelectron Microscopy620245710.580 Why?
Mitochondrial Proteins120239960.570 Why?
Histone Deacetylases120217280.560 Why?
Acetamides120182490.560 Why?
Proteins4202361030.540 Why?
Cell Cycle Proteins4202134620.520 Why?
Proteome3202217990.510 Why?
Polymers1202216210.500 Why?
Immunologic Factors2202215800.490 Why?
Tumor Suppressor Proteins4202428490.460 Why?
Thiophenes120185880.460 Why?
Protein Kinases1202016400.460 Why?
Crystallography, X-Ray10202120110.450 Why?
Sulfonamides2202019380.450 Why?
Models, Molecular10202154560.440 Why?
Intracellular Signaling Peptides and Proteins3201929150.440 Why?
Peptide Termination Factors22022550.400 Why?
Ubiquitin320238520.400 Why?
Indoles1201918390.390 Why?
Molecular Structure5202118990.390 Why?
Protein Binding12202393860.380 Why?
Polymerization220221640.380 Why?
Antibodies, Viral4202331760.370 Why?
Apoptosis7202497270.370 Why?
Biocatalysis320231670.370 Why?
DNA-Binding Proteins7202196480.370 Why?
Lymphoma, T-Cell220232990.360 Why?
Drug Resistance, Neoplasm8202351720.360 Why?
Ligands8202332820.350 Why?
Cell Line82024159970.350 Why?
Cyclins220236030.350 Why?
Von Hippel-Lindau Tumor Suppressor Protein220212900.350 Why?
Casein Kinase Ialpha22021270.350 Why?
Methyltransferases220233670.340 Why?
Fluorescence Resonance Energy Transfer220234010.340 Why?
Zinc Fingers220245850.330 Why?
Cell Line, Tumor232021166890.320 Why?
Nuclear Proteins4202258530.320 Why?
Antineoplastic Agents112023136950.320 Why?
HEK293 Cells5202142040.310 Why?
T-Lymphocytes, Regulatory1202129880.300 Why?
Kinetics5202164730.290 Why?
Phthalimides22024250.280 Why?
Cyclin-Dependent Kinase 6220193220.280 Why?
Multiprotein Complexes4202011190.270 Why?
Amino Acid Motifs220199360.270 Why?
Multiple Myeloma5202251810.260 Why?
Humans7320247443430.250 Why?
Neoplasms62024216830.250 Why?
Binding Sites8202361140.250 Why?
Leukemia2202315110.240 Why?
Piperidones12024280.240 Why?
Enzyme Activation3202337010.230 Why?
Factor V120241780.230 Why?
Dibenzazepines12022260.220 Why?
RNA, Transfer220233160.220 Why?
Cell Nucleus3202329690.220 Why?
Nucleocapsid12023590.220 Why?
Piperazines4202124880.220 Why?
Directed Molecular Evolution120241600.220 Why?
Cytokine Receptor Common beta Subunit12022220.220 Why?
RNA Processing, Post-Transcriptional220234360.210 Why?
Mitogen-Activated Protein Kinase 712022660.210 Why?
Cyclic Nucleotide Phosphodiesterases, Type 612021290.210 Why?
Cyclin-Dependent Kinase Inhibitor Proteins12021550.210 Why?
Cyclin-Dependent Kinase 922021660.200 Why?
DNA Damage5201924320.200 Why?
tRNA Methyltransferases12021530.200 Why?
Immunoglobulin G3202245600.200 Why?
Myeloid-Lymphoid Leukemia Protein120242940.200 Why?
Methanol12021850.200 Why?
Carrier Proteins4202350210.200 Why?
Proto-Oncogene Protein c-fli-1120211050.190 Why?
Chimera120224850.190 Why?
Phosphodiesterase Inhibitors120212150.190 Why?
Morpholines120245710.190 Why?
Pyrrolidines120223420.190 Why?
Indoleacetic Acids12020440.190 Why?
Eukaryotic Initiation Factor-4E120211070.190 Why?
Pyridines3202128250.190 Why?
Protein Tyrosine Phosphatase, Non-Receptor Type 11120212340.190 Why?
Eukaryota12021990.190 Why?
Molecular Conformation220195630.180 Why?
Oncogenes2202312650.180 Why?
Cell Proliferation92023104810.180 Why?
Proto-Oncogene Proteins c-bcl-6120201930.180 Why?
Receptor, Fibroblast Growth Factor, Type 2120211880.180 Why?
RNA-Binding Protein EWS120212160.180 Why?
Proteasome Endopeptidase Complex3202013380.180 Why?
Receptor, Fibroblast Growth Factor, Type 1120212500.180 Why?
Cyclin-Dependent Kinase 2120201910.180 Why?
Cyclin-Dependent Kinase 5120201120.180 Why?
Spodoptera120191530.180 Why?
Oncogene Proteins220217490.180 Why?
NF-E2-Related Factor 2120223770.170 Why?
Cross Reactions120218410.170 Why?
Jurkat Cells120217430.170 Why?
HCT116 Cells220174080.170 Why?
Chromatin4202329340.170 Why?
Inflammasomes120244950.170 Why?
Lower Extremity Deformities, Congenital12018120.170 Why?
Mitogen-Activated Protein Kinases1202412850.170 Why?
Cyclin-Dependent Kinase 4220195380.160 Why?
Leukemia, Myeloid, Acute3202435230.160 Why?
Databases, Protein120203830.160 Why?
Upper Extremity Deformities, Congenital12018290.160 Why?
Protein Phosphatase 2120202290.160 Why?
GTP-Binding Proteins120239700.160 Why?
Mutation82024297860.160 Why?
Nuclear Magnetic Resonance, Biomolecular120215070.160 Why?
Lysine1202210070.160 Why?
Teratogens120181120.160 Why?
Animals1720241687570.150 Why?
Immunologic Surveillance12018930.150 Why?
Viral Nonstructural Proteins120192410.150 Why?
Xenopus120197120.150 Why?
Phosphorylation7202384360.150 Why?
Dose-Response Relationship, Drug22021109430.150 Why?
Cullin Proteins320161800.150 Why?
Pyrimidinones120193710.150 Why?
Species Specificity2201824780.150 Why?
Immunity, Humoral120215980.150 Why?
Mammals1202211430.150 Why?
Oncogene Proteins, Fusion2202315810.140 Why?
Purines120205940.140 Why?
Lymphoma, B-Cell120239310.140 Why?
Leukocytes, Mononuclear1202418360.140 Why?
Biphenyl Compounds120219130.140 Why?
Isoenzymes1202117260.140 Why?
Nucleotidyltransferases120182200.140 Why?
Tubulin120206950.140 Why?
Protein Structure, Secondary1201912460.140 Why?
Lymphoma, Mantle-Cell120182330.140 Why?
Histone Deacetylase Inhibitors120217890.140 Why?
Signal Transduction82023234030.140 Why?
Frontotemporal Dementia120192480.130 Why?
Catalytic Domain420236980.130 Why?
Protein Interaction Mapping120196270.130 Why?
Acrylamides120172550.130 Why?
Pyrazines1202112300.130 Why?
Protease Inhibitors120197910.130 Why?
Tauopathies120193070.130 Why?
Mice122024811830.130 Why?
Proto-Oncogene Proteins c-akt2202425030.130 Why?
Heart Septal Defects, Atrial120184780.130 Why?
Lysosomes120208930.130 Why?
Ubiquitins320233840.130 Why?
Autophagy1202313000.130 Why?
Quinazolines2202113560.120 Why?
Cell Survival3202158820.120 Why?
Principal Component Analysis120179400.120 Why?
Drug Resistance, Viral120198200.120 Why?
fms-Like Tyrosine Kinase 3120174910.120 Why?
Benzamides1201913790.120 Why?
Stress, Physiological1202114030.120 Why?
Receptors, G-Protein-Coupled1202112220.110 Why?
Pyrimidines3201929420.110 Why?
GTP Phosphohydrolases120165090.110 Why?
Focal Adhesion Protein-Tyrosine Kinases220231820.110 Why?
Waldenstrom Macroglobulinemia1202110520.110 Why?
Xeroderma Pigmentosum Group A Protein12011130.110 Why?
Neuroprotective Agents120199410.100 Why?
Pyrazoles2201919720.100 Why?
Proto-Oncogene Proteins p21(ras)1201916920.100 Why?
ras Proteins1201710600.100 Why?
Guanine Nucleotide Exchange Factors120165810.100 Why?
Hormones120168890.100 Why?
Abnormalities, Multiple1201814160.090 Why?
Embryonic Stem Cells1201812940.090 Why?
RNA-Binding Proteins1201919030.090 Why?
Proto-Oncogene Proteins1202345540.090 Why?
Protein-Tyrosine Kinases1201924550.090 Why?
Ultraviolet Rays2201510600.090 Why?
Protein Stability220225570.090 Why?
Mass Spectrometry1201722030.090 Why?
Endothelial Cells1202234790.090 Why?
Enzyme Inhibitors1202037980.090 Why?
tau Proteins1201918680.090 Why?
Gene Deletion1201727510.080 Why?
Bone Neoplasms1202125290.080 Why?
RNA, Messenger22021130330.080 Why?
Nerve Tissue Proteins1202144620.080 Why?
DNA Repair2202320460.080 Why?
Lung Neoplasms32023131020.080 Why?
Myelodysplastic Syndromes1201713520.070 Why?
Allosteric Regulation220204080.070 Why?
Antiviral Agents1201929870.070 Why?
Amino Acid Sequence12018138150.070 Why?
Protein Structure, Tertiary3201838460.060 Why?
Breast Neoplasms22024208220.060 Why?
Pandemics2202283880.060 Why?
Homeodomain Proteins1201424210.060 Why?
Cells, Cultured12020192290.060 Why?
Mutagenesis, Site-Directed2201817230.060 Why?
DNA1201873010.060 Why?
Mitogens120242320.060 Why?
Co-Repressor Proteins120231940.050 Why?
Allosteric Site120221030.050 Why?
Protein Conformation2202240110.050 Why?
Coronavirus OC43, Human12021180.050 Why?
JNK Mitogen-Activated Protein Kinases120244520.050 Why?
Interleukin-5120222730.050 Why?
Tumor Cells, Cultured2202163140.050 Why?
Heart Defects, Congenital1201845840.050 Why?
Guanosine12021610.050 Why?
Interleukin-3120224440.050 Why?
Genes, Overlapping12021360.050 Why?
Immunologic Tests120211030.050 Why?
Mitogen-Activated Protein Kinase Kinases120246480.050 Why?
Erythroid Cells120222380.050 Why?
p38 Mitogen-Activated Protein Kinases120246970.050 Why?
Trans-Activators2202129240.050 Why?
Phenotype12018163650.050 Why?
Female820243801940.050 Why?
Phenothiazines12020630.050 Why?
Young Adult32021564300.050 Why?
Enzyme Activators12020570.050 Why?
Hydrogen Bonding120202930.050 Why?
Asymptomatic Infections120211280.050 Why?
Dipeptides120224090.050 Why?
Reproducibility of Results12018199050.050 Why?
Benzylamines120212230.040 Why?
Recombinant Proteins2202166220.040 Why?
Immunoglobulin Class Switching120212910.040 Why?
Imides12019150.040 Why?
Solvents120203020.040 Why?
Neurons1201993380.040 Why?
Chromatin Assembly and Disassembly120246350.040 Why?
Adolescent32022857810.040 Why?
Models, Immunological120215270.040 Why?
Prodrugs120212680.040 Why?
Granulocyte-Macrophage Colony-Stimulating Factor120229030.040 Why?
Asymptomatic Diseases120215510.040 Why?
G1 Phase120204150.040 Why?
Receptors, Cytoplasmic and Nuclear120238710.040 Why?
Aminopyridines120225420.040 Why?
Synthetic Biology120201790.040 Why?
Serine120228260.040 Why?
Methylation1202111060.040 Why?
Gene Knockout Techniques120218090.040 Why?
Interleukin-1beta120249720.040 Why?
Cytoplasm1202215390.040 Why?
Protein Transport1202419880.040 Why?
Nucleotides, Cyclic12018810.040 Why?
Receptors, Fc120215410.040 Why?
Genome, Human1201144200.040 Why?
Benzofurans120181400.040 Why?
Ubiquitin-Conjugating Enzymes120181950.040 Why?
Drug Screening Assays, Antitumor120207300.040 Why?
Gene Expression2202277990.040 Why?
Immunoglobulin A120219920.040 Why?
Phthalazines120193630.040 Why?
Carrier State120215180.040 Why?
Transcriptional Activation1202317830.040 Why?
Inhibitory Concentration 50120174590.040 Why?
Cell Death1202217060.040 Why?
Cyclin-Dependent Kinases120206710.040 Why?
Oxazoles120171890.040 Why?
Protein Subunits120209590.040 Why?
Apoproteins12016440.040 Why?
Protein Engineering120205400.030 Why?
Immunocompromised Host120218470.030 Why?
Immunity, Cellular1202216070.030 Why?
Microfilament Proteins1202111520.030 Why?
Systemic Inflammatory Response Syndrome120216120.030 Why?
Sulfones120184370.030 Why?
Interleukin-21202219040.030 Why?
Receptor Protein-Tyrosine Kinases1202316600.030 Why?
Chemotaxis120186070.030 Why?
Intercellular Signaling Peptides and Proteins1202216760.030 Why?
Basic Helix-Loop-Helix Transcription Factors1202111140.030 Why?
Immunity1202110120.030 Why?
Molecular Dynamics Simulation120174130.030 Why?
Protein Processing, Post-Translational1202319900.030 Why?
Gene Knockdown Techniques1201916550.030 Why?
Amides120174590.030 Why?
Mice, Inbred NOD1201818780.030 Why?
Age of Onset1202132710.030 Why?
Receptors, Antigen, T-Cell1202325400.030 Why?
Oligopeptides1201911890.030 Why?
Adenine120189360.030 Why?
Mice, SCID1201827160.030 Why?
Protein Multimerization120189700.030 Why?
Cell Division1202045680.030 Why?
Vibrio cholerae120188060.030 Why?
Hepacivirus1201913790.030 Why?
Antibodies, Neutralizing1202119780.020 Why?
Survivors1202122910.020 Why?
Repressor Proteins1202230230.020 Why?
Xenograft Model Antitumor Assays1201835570.020 Why?
Thiazoles1201714830.020 Why?
Piperidines1201816020.020 Why?
Gene Regulatory Networks1201817080.020 Why?
MAP Kinase Signaling System1201715260.020 Why?
Middle Aged220212133830.020 Why?
Molecular Targeted Therapy1202127270.020 Why?
Hematopoietic Stem Cells1202233860.020 Why?
Adult220212140550.020 Why?
Risk1202196870.020 Why?
DNA Repair Enzymes120113490.020 Why?
Macrophages1202456550.020 Why?
Hepatitis C1201915910.020 Why?
Male320213501180.020 Why?
Cohort Studies22021405610.020 Why?
Models, Theoretical1201935890.020 Why?
Immunotherapy1202144450.020 Why?
T-Lymphocytes12023101800.020 Why?
Disease Progression12021132840.020 Why?
Genomics1202157200.020 Why?
Gene Expression Regulation, Neoplastic1202184280.020 Why?
Disease Models, Animal12023180290.020 Why?
Ovarian Neoplasms1202048380.010 Why?
Severity of Illness Index12021155400.010 Why?
Inflammation12022106380.010 Why?
Genome-Wide Association Study12021122610.010 Why?
Models, Genetic1201134940.010 Why?
Infant, Newborn12021256250.010 Why?
Carcinoma, Non-Small-Cell Lung1201852210.010 Why?
Infant12021351360.010 Why?
Child, Preschool12021410060.010 Why?
Prospective Studies12021532880.010 Why?
Child12021777090.010 Why?
Aged120211632800.010 Why?
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Concepts (341)
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.