Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Eric Sebastian Fischer, Ph.D.

Concepts (335)

Concepts are derived automatically from a person's publications.
Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.
Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Ubiquitin-Protein Ligases27202318473.010 Why?
Thalidomide1120238782.000 Why?
Peptide Hydrolases720186271.480 Why?
Ikaros Transcription Factor720222131.110 Why?
Small Molecule Libraries820217281.110 Why?
Transcription Factors142023121340.920 Why?
Ubiquitination15202310030.870 Why?
Inhibitor of Apoptosis Proteins120232150.820 Why?
Apoptosis Regulatory Proteins2202311570.760 Why?
Adaptor Proteins, Signal Transducing13202229080.740 Why?
Substrate Specificity8202317990.720 Why?
Caspases120239270.700 Why?
Proteomics9202435840.660 Why?
Protein Kinase Inhibitors13202355000.640 Why?
Drug Design4202110860.630 Why?
Drug Discovery3202110560.630 Why?
Duane Retraction Syndrome12018600.620 Why?
Structure-Activity Relationship8202331420.600 Why?
Mitochondrial Proteins120239890.570 Why?
Histone Deacetylases120217290.570 Why?
Acetamides120182480.560 Why?
Proteins4202360740.540 Why?
Cryoelectron Microscopy520235670.540 Why?
Cell Cycle Proteins4202134320.520 Why?
Proteome3202217720.510 Why?
Polymers1202216110.500 Why?
Immunologic Factors2202215710.490 Why?
Thiophenes120185890.460 Why?
Protein Kinases1202016370.460 Why?
Crystallography, X-Ray10202120140.450 Why?
Sulfonamides2202019340.450 Why?
Models, Molecular10202154580.440 Why?
Intracellular Signaling Peptides and Proteins3201929020.440 Why?
Tumor Suppressor Proteins3202328430.440 Why?
Peptide Termination Factors22022570.400 Why?
Ubiquitin320238470.400 Why?
Indoles1201918330.390 Why?
Molecular Structure5202119170.390 Why?
Protein Binding12202393810.380 Why?
Polymerization220221630.380 Why?
Antibodies, Viral4202331510.380 Why?
Apoptosis7202497080.370 Why?
Biocatalysis320231660.370 Why?
DNA-Binding Proteins7202196250.370 Why?
Lymphoma, T-Cell220232990.360 Why?
Drug Resistance, Neoplasm8202351480.360 Why?
Ligands8202333010.350 Why?
Cell Line82024159820.350 Why?
Cyclins220236010.350 Why?
Von Hippel-Lindau Tumor Suppressor Protein220212900.350 Why?
Casein Kinase Ialpha22021260.350 Why?
Methyltransferases220233660.340 Why?
Fluorescence Resonance Energy Transfer220234010.340 Why?
Cell Line, Tumor232021166240.330 Why?
Nuclear Proteins4202258330.320 Why?
Antineoplastic Agents112023136220.320 Why?
HEK293 Cells5202141740.310 Why?
T-Lymphocytes, Regulatory1202129850.300 Why?
Kinetics5202164730.290 Why?
Cyclin-Dependent Kinase 6220193220.280 Why?
Multiprotein Complexes4202011190.270 Why?
Amino Acid Motifs220199400.270 Why?
Multiple Myeloma5202251470.260 Why?
Humans7020247392190.250 Why?
Binding Sites8202361160.250 Why?
Leukemia2202315030.240 Why?
Enzyme Activation3202336980.230 Why?
Dibenzazepines12022260.230 Why?
RNA, Transfer220233170.220 Why?
Cell Nucleus3202329670.220 Why?
Nucleocapsid12023550.220 Why?
Neoplasms52023214990.220 Why?
Piperazines4202124800.220 Why?
Cytokine Receptor Common beta Subunit12022220.220 Why?
RNA Processing, Post-Transcriptional220234350.210 Why?
Mitogen-Activated Protein Kinase 712022650.210 Why?
Cyclic Nucleotide Phosphodiesterases, Type 612021300.210 Why?
Cyclin-Dependent Kinase Inhibitor Proteins12021550.210 Why?
Cyclin-Dependent Kinase 922021660.200 Why?
DNA Damage5201924160.200 Why?
tRNA Methyltransferases12021530.200 Why?
Immunoglobulin G3202245210.200 Why?
Methanol12021830.200 Why?
Carrier Proteins4202350120.200 Why?
Proto-Oncogene Protein c-fli-1120211010.190 Why?
Chimera120224880.190 Why?
Phosphodiesterase Inhibitors120212150.190 Why?
Pyrrolidines120223410.190 Why?
Indoleacetic Acids12020440.190 Why?
Pyridines3202128090.190 Why?
Eukaryotic Initiation Factor-4E120211060.190 Why?
Protein Tyrosine Phosphatase, Non-Receptor Type 11120212340.190 Why?
Eukaryota12021990.190 Why?
Molecular Conformation220195620.190 Why?
Oncogenes2202312620.180 Why?
Cell Proliferation92023104460.180 Why?
Receptor, Fibroblast Growth Factor, Type 2120211860.180 Why?
Proto-Oncogene Proteins c-bcl-6120201920.180 Why?
RNA-Binding Protein EWS120212090.180 Why?
Proteasome Endopeptidase Complex3202013300.180 Why?
Receptor, Fibroblast Growth Factor, Type 1120212500.180 Why?
Cyclin-Dependent Kinase 2120201910.180 Why?
Cyclin-Dependent Kinase 5120201120.180 Why?
Spodoptera120191510.180 Why?
Oncogene Proteins220217490.180 Why?
NF-E2-Related Factor 2120223640.180 Why?
Cross Reactions120218400.180 Why?
Jurkat Cells120217410.170 Why?
HCT116 Cells220174070.170 Why?
Chromatin4202328780.170 Why?
Inflammasomes120244870.170 Why?
Lower Extremity Deformities, Congenital12018120.170 Why?
Cyclin-Dependent Kinase 4220195280.170 Why?
Mitogen-Activated Protein Kinases1202412860.170 Why?
Databases, Protein120203820.160 Why?
Upper Extremity Deformities, Congenital12018280.160 Why?
Protein Phosphatase 2120202300.160 Why?
GTP-Binding Proteins120239720.160 Why?
Nuclear Magnetic Resonance, Biomolecular120215030.160 Why?
Lysine1202210060.160 Why?
Teratogens120181130.160 Why?
Animals1720241683580.160 Why?
Immunologic Surveillance12018930.160 Why?
Viral Nonstructural Proteins120192420.150 Why?
Xenopus120197110.150 Why?
Phosphorylation7202384140.150 Why?
Dose-Response Relationship, Drug22021109390.150 Why?
Cullin Proteins320161800.150 Why?
Pyrimidinones120193710.150 Why?
Mammals1202211160.150 Why?
Species Specificity2201824810.150 Why?
Immunity, Humoral120215950.150 Why?
Leukocytes, Mononuclear1202418210.140 Why?
Oncogene Proteins, Fusion2202315740.140 Why?
Lymphoma, B-Cell120239300.140 Why?
Purines120205930.140 Why?
Biphenyl Compounds120219090.140 Why?
Isoenzymes1202117200.140 Why?
Nucleotidyltransferases120182190.140 Why?
Tubulin120206960.140 Why?
Protein Structure, Secondary1201912450.140 Why?
Lymphoma, Mantle-Cell120182320.140 Why?
Mutation62023296590.140 Why?
Frontotemporal Dementia120192380.140 Why?
Histone Deacetylase Inhibitors120217880.140 Why?
Signal Transduction82023233550.140 Why?
Catalytic Domain420236980.130 Why?
Acrylamides120172500.130 Why?
Protein Interaction Mapping120196270.130 Why?
Tauopathies120193040.130 Why?
Protease Inhibitors120197920.130 Why?
Pyrazines1202112320.130 Why?
Mice122024809950.130 Why?
Heart Septal Defects, Atrial120184750.130 Why?
Proto-Oncogene Proteins c-akt2202425070.130 Why?
Lysosomes120208950.130 Why?
Autophagy1202312910.130 Why?
Ubiquitins320233820.130 Why?
Zinc Fingers120175810.130 Why?
Quinazolines2202113560.120 Why?
Cell Survival3202158730.120 Why?
Principal Component Analysis120179370.120 Why?
Drug Resistance, Viral120198290.120 Why?
Benzamides1201913730.120 Why?
fms-Like Tyrosine Kinase 3120174930.120 Why?
Stress, Physiological1202114020.120 Why?
Receptors, G-Protein-Coupled1202112140.120 Why?
Pyrimidines3201929170.110 Why?
GTP Phosphohydrolases120165070.110 Why?
Focal Adhesion Protein-Tyrosine Kinases220231830.110 Why?
Waldenstrom Macroglobulinemia1202110500.110 Why?
Xeroderma Pigmentosum Group A Protein12011130.110 Why?
Pyrazoles2201919620.110 Why?
Proto-Oncogene Proteins p21(ras)1201916710.110 Why?
Neuroprotective Agents120199400.110 Why?
ras Proteins1201710600.100 Why?
Guanine Nucleotide Exchange Factors120165780.100 Why?
Hormones120168800.100 Why?
Abnormalities, Multiple1201814050.100 Why?
Embryonic Stem Cells1201812940.100 Why?
RNA-Binding Proteins1201918930.090 Why?
Proto-Oncogene Proteins1202345490.090 Why?
Protein-Tyrosine Kinases1201924540.090 Why?
Ultraviolet Rays2201510590.090 Why?
Protein Stability220225540.090 Why?
Endothelial Cells1202234330.090 Why?
Mass Spectrometry1201721990.090 Why?
Enzyme Inhibitors1202038000.090 Why?
tau Proteins1201918450.090 Why?
Gene Deletion1201727570.080 Why?
Leukemia, Myeloid, Acute2202234870.080 Why?
Bone Neoplasms1202125210.080 Why?
RNA, Messenger22021130060.080 Why?
Nerve Tissue Proteins1202144640.080 Why?
DNA Repair2202320320.080 Why?
Lung Neoplasms32023129830.080 Why?
Myelodysplastic Syndromes1201713450.070 Why?
Allosteric Regulation220204070.070 Why?
Antiviral Agents1201929710.070 Why?
Amino Acid Sequence12018138150.070 Why?
Protein Structure, Tertiary3201838490.070 Why?
Breast Neoplasms22024206720.070 Why?
Pandemics2202282740.060 Why?
Homeodomain Proteins1201424100.060 Why?
Cells, Cultured12020192230.060 Why?
Mutagenesis, Site-Directed2201817210.060 Why?
DNA1201872780.060 Why?
Mitogens120242320.060 Why?
Co-Repressor Proteins120231930.050 Why?
Allosteric Site120221030.050 Why?
Protein Conformation2202240130.050 Why?
Coronavirus OC43, Human12021180.050 Why?
JNK Mitogen-Activated Protein Kinases120244520.050 Why?
Interleukin-5120222730.050 Why?
Tumor Cells, Cultured2202163100.050 Why?
Heart Defects, Congenital1201845460.050 Why?
Guanosine12021600.050 Why?
Interleukin-3120224410.050 Why?
Genes, Overlapping12021360.050 Why?
Immunologic Tests120211040.050 Why?
Mitogen-Activated Protein Kinase Kinases120246470.050 Why?
Erythroid Cells120222380.050 Why?
p38 Mitogen-Activated Protein Kinases120246910.050 Why?
Trans-Activators2202129210.050 Why?
Phenotype12018163000.050 Why?
Female820243788080.050 Why?
Phenothiazines12020630.050 Why?
Young Adult32021562520.050 Why?
Enzyme Activators12020570.050 Why?
Hydrogen Bonding120202930.050 Why?
Asymptomatic Infections120211290.050 Why?
Reproducibility of Results12018197870.050 Why?
Dipeptides120224090.050 Why?
Benzylamines120212260.040 Why?
Recombinant Proteins2202166090.040 Why?
Immunoglobulin Class Switching120212910.040 Why?
Imides12019150.040 Why?
Solvents120203010.040 Why?
Neurons1201993400.040 Why?
Adolescent32022854090.040 Why?
Phthalimides12018130.040 Why?
Models, Immunological120215270.040 Why?
Prodrugs120212680.040 Why?
Granulocyte-Macrophage Colony-Stimulating Factor120229030.040 Why?
Asymptomatic Diseases120215490.040 Why?
G1 Phase120204140.040 Why?
Receptors, Cytoplasmic and Nuclear120238630.040 Why?
Aminopyridines120225390.040 Why?
Methylation1202111060.040 Why?
Synthetic Biology120201800.040 Why?
Serine120228310.040 Why?
Gene Knockout Techniques120218040.040 Why?
Interleukin-1beta120249700.040 Why?
Cytoplasm1202215360.040 Why?
Protein Transport1202419880.040 Why?
Receptors, Fc120215390.040 Why?
Nucleotides, Cyclic12018810.040 Why?
Genome, Human1201144240.040 Why?
Benzofurans120181410.040 Why?
Ubiquitin-Conjugating Enzymes120181930.040 Why?
Drug Screening Assays, Antitumor120207370.040 Why?
Gene Expression2202277890.040 Why?
Phthalazines120193570.040 Why?
Immunoglobulin A120219890.040 Why?
Carrier State120215170.040 Why?
Transcriptional Activation1202317810.040 Why?
Inhibitory Concentration 50120174640.040 Why?
Cell Death1202216910.040 Why?
Cyclin-Dependent Kinases120206700.040 Why?
Oxazoles120171900.040 Why?
Protein Subunits120209650.040 Why?
Apoproteins12016440.040 Why?
Immunocompromised Host120218450.040 Why?
Protein Engineering120205430.030 Why?
Immunity, Cellular1202216010.030 Why?
Microfilament Proteins1202111500.030 Why?
Systemic Inflammatory Response Syndrome120216060.030 Why?
Sulfones120184360.030 Why?
Interleukin-21202218840.030 Why?
Receptor Protein-Tyrosine Kinases1202316590.030 Why?
Chemotaxis120186020.030 Why?
Intercellular Signaling Peptides and Proteins1202216770.030 Why?
Basic Helix-Loop-Helix Transcription Factors1202111160.030 Why?
Immunity1202110090.030 Why?
Molecular Dynamics Simulation120174090.030 Why?
Protein Processing, Post-Translational1202319890.030 Why?
Amides120174580.030 Why?
Gene Knockdown Techniques1201916520.030 Why?
Mice, Inbred NOD1201818660.030 Why?
Age of Onset1202132630.030 Why?
Receptors, Antigen, T-Cell1202325180.030 Why?
Oligopeptides1201911790.030 Why?
Adenine120189400.030 Why?
Mice, SCID1201827140.030 Why?
Protein Multimerization120189690.030 Why?
Cell Division1202045750.030 Why?
Hepacivirus1201913710.030 Why?
Vibrio cholerae120188060.030 Why?
Antibodies, Neutralizing1202119570.020 Why?
Survivors1202122800.020 Why?
Repressor Proteins1202230080.020 Why?
Xenograft Model Antitumor Assays1201835570.020 Why?
Piperidines1201815970.020 Why?
Thiazoles1201714860.020 Why?
MAP Kinase Signaling System1201715220.020 Why?
Gene Regulatory Networks1201817080.020 Why?
Hematopoietic Stem Cells1202233690.020 Why?
Middle Aged220212128330.020 Why?
Molecular Targeted Therapy1202127270.020 Why?
Adult220212133750.020 Why?
Risk1202196840.020 Why?
DNA Repair Enzymes120113470.020 Why?
Hepatitis C1201915800.020 Why?
Macrophages1202456310.020 Why?
Male320213489670.020 Why?
Cohort Studies22021403850.020 Why?
Models, Theoretical1201936050.020 Why?
Immunotherapy1202143890.020 Why?
T-Lymphocytes12023101400.020 Why?
Disease Progression12021132370.020 Why?
Genomics1202156550.020 Why?
Gene Expression Regulation, Neoplastic1202183950.020 Why?
Disease Models, Animal12023180020.020 Why?
Ovarian Neoplasms1202048130.010 Why?
Severity of Illness Index12021155100.010 Why?
Inflammation12022105310.010 Why?
Genome-Wide Association Study12021121770.010 Why?
Infant, Newborn12021254700.010 Why?
Models, Genetic1201134950.010 Why?
Carcinoma, Non-Small-Cell Lung1201851530.010 Why?
Infant12021349230.010 Why?
Child, Preschool12021408010.010 Why?
Prospective Studies12021530360.010 Why?
Child12021770290.010 Why?
Aged120211626670.010 Why?
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Concepts (335)
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.