Harvard Catalyst Profiles

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Sara Buhrlage, Ph.D.

Concepts (276)

Concepts are derived automatically from a person's publications.
Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.
Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Ubiquitin1020238492.450 Why?
Small Molecule Libraries920217212.360 Why?
Enzyme Inhibitors5202138001.450 Why?
Protease Inhibitors420207901.180 Why?
Drug Discovery7202210571.050 Why?
Thiophenes320185900.910 Why?
Ubiquitin Thiolesterase520234490.880 Why?
Myeloid Differentiation Factor 88720225710.840 Why?
fms-Like Tyrosine Kinase 3520204910.810 Why?
Protein Kinase Inhibitors15202155220.810 Why?
Rhodamines120211830.780 Why?
Endopeptidases220237720.720 Why?
Ubiquitination9202310110.720 Why?
Sumoylation12019830.650 Why?
Janus Kinase 2120215270.630 Why?
Leukemia, Myeloid, Acute4202134970.590 Why?
High-Throughput Screening Assays320219440.570 Why?
Molecular Structure8202119070.510 Why?
Myeloproliferative Disorders120216030.510 Why?
Structure-Activity Relationship10202331330.510 Why?
Tumor Suppressor Protein p532202029480.420 Why?
Proto-Oncogene Proteins c-hck32022460.400 Why?
Interleukin-1 Receptor-Associated Kinases32019780.350 Why?
Drug Design7202110780.330 Why?
Molecular Mimicry120092010.320 Why?
Proteomics5202336180.320 Why?
Mutation112021297170.300 Why?
Tumor Cells, Cultured5202163130.280 Why?
Cell Proliferation92021104720.270 Why?
Antineoplastic Agents82021136550.270 Why?
Cell Line, Tumor172022166650.250 Why?
Protein Kinases5202316380.250 Why?
Staurosporine320202510.250 Why?
Cell Survival7201958720.250 Why?
Pyrimidines4201829330.240 Why?
Pyrazoles4201919700.230 Why?
Apoptosis6202197150.230 Why?
Models, Molecular6201954540.230 Why?
Benzothiazoles320202470.220 Why?
Piperidines6202116020.220 Why?
Electrophoresis, Microchip12022140.220 Why?
Proto-Oncogene Proteins c-cbl220201190.220 Why?
Adenine420219360.210 Why?
Phosphatidylethanolamines120221340.210 Why?
Lymphoma, B-Cell220229300.210 Why?
Trans-Activators2201629240.200 Why?
Catalytic Domain320196990.200 Why?
Substrate Specificity4202018020.190 Why?
Herpesvirus 8, Human120232580.190 Why?
Enzyme Assays120211110.190 Why?
Protein-Tyrosine Kinases3201524550.190 Why?
Drug Screening Assays, Antitumor320197310.180 Why?
Polyomavirus Infections120221960.180 Why?
Mutant Proteins220195000.180 Why?
Sarcoma, Kaposi120233700.180 Why?
Peptide Hydrolases120236270.180 Why?
Lymphoma2202118730.180 Why?
Lymphoma, Large B-Cell, Diffuse3202013770.170 Why?
Quinolines220167190.170 Why?
Antifungal Agents220167290.170 Why?
Dose-Response Relationship, Drug52017109430.170 Why?
Hematologic Neoplasms2202218200.160 Why?
Proteome4202217900.160 Why?
Carcinoma, Merkel Cell120222990.160 Why?
Drug Repositioning120202290.160 Why?
Protein Multimerization320179710.150 Why?
Waldenstrom Macroglobulinemia3201610520.150 Why?
Phosphorylation5202184360.150 Why?
raf Kinases120171220.150 Why?
Mice, Inbred NOD2202118750.150 Why?
Humans5120237420880.140 Why?
Isoxazoles220092160.140 Why?
Protein Tyrosine Phosphatase, Non-Receptor Type 11120172340.140 Why?
Oncogene Proteins120217490.140 Why?
Leukemia, Myeloid120207050.140 Why?
Paracrine Communication120182760.140 Why?
Glutathione120195860.140 Why?
Candida glabrata12016330.140 Why?
Drug Resistance, Fungal12016510.140 Why?
Immunity1202210110.140 Why?
Leukemia2201515070.140 Why?
Transcriptional Activation4201617820.130 Why?
HEK293 Cells3202142000.130 Why?
Mediator Complex120161090.130 Why?
Heterocyclic Compounds, 3-Ring120172150.130 Why?
Fluconazole220161460.130 Why?
Pyrimidinones120173700.130 Why?
vif Gene Products, Human Immunodeficiency Virus12015530.130 Why?
Benzodiazepinones12014510.120 Why?
Inhibitor of Differentiation Protein 112013470.120 Why?
Mass Spectrometry1202122030.120 Why?
Fluorescent Dyes1202119150.120 Why?
T-Lymphocytes, Cytotoxic1202118200.110 Why?
Cytidine Deaminase120152510.110 Why?
MAP Kinase Kinase Kinases120142610.110 Why?
Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization120145030.110 Why?
Transcription Factors32021121640.110 Why?
Astrocytoma120177890.110 Why?
Gene Dosage1201712510.100 Why?
Neoplasms, Experimental1201712740.100 Why?
Killer Cells, Natural1202121330.100 Why?
Arabidopsis Proteins120132620.100 Why?
Recombinant Proteins1202166080.100 Why?
Patents as Topic120121030.100 Why?
Fungal Proteins120169120.100 Why?
Antiparkinson Agents120121830.100 Why?
Histones1202225970.100 Why?
Homeostasis1202233350.100 Why?
Gene Expression Regulation, Enzymologic1201612130.100 Why?
Antioxidants1201916590.100 Why?
Anilides120144040.090 Why?
MAP Kinase Signaling System1201815250.090 Why?
Animals1620221685610.090 Why?
Tandem Mass Spectrometry1201611570.090 Why?
Molecular Conformation220165630.090 Why?
Dendritic Cells1202127230.090 Why?
Protein Binding6201993870.090 Why?
Escherichia coli1202142140.090 Why?
Stereoisomerism220116250.080 Why?
Oncogene Proteins, Fusion1201715810.080 Why?
Xenograft Model Antitumor Assays4201935570.080 Why?
CREB-Binding Protein120091510.080 Why?
Mice112021810450.080 Why?
HSP90 Heat-Shock Proteins120114340.080 Why?
Cysteine120138730.080 Why?
Candida albicans120113940.080 Why?
Binding Sites3201661150.080 Why?
Antiviral Agents1202029780.080 Why?
Leukocytes, Mononuclear1201518350.080 Why?
Phosphoproteins1201724400.080 Why?
Gene Expression Regulation, Neoplastic3202284250.080 Why?
Neoplasm Proteins2201836910.070 Why?
Proto-Oncogene Proteins B-raf1201720280.070 Why?
Drug Resistance, Neoplasm2202151630.070 Why?
Phenylurea Compounds220205260.070 Why?
Lymphocytes1201326140.060 Why?
Genome, Human1201844200.060 Why?
Aminopyridines220195410.060 Why?
Intracellular Signaling Peptides and Proteins1201529060.060 Why?
Drug Synergism2202017910.060 Why?
Aniline Compounds220209830.060 Why?
Peptides1201643920.060 Why?
Benzimidazoles220208480.060 Why?
Cells, Cultured52020192230.060 Why?
Pyrazines2202012310.060 Why?
Crystallography, X-Ray2201920140.060 Why?
Up-Regulation2201642110.060 Why?
Lymphoma, Primary Effusion12023170.060 Why?
Inhibitory Concentration 50220144590.060 Why?
Protein Structure, Tertiary3201638470.060 Why?
Multiple Myeloma1202151690.050 Why?
Skin Neoplasms1202256620.050 Why?
Toll-Like Receptor 112022480.050 Why?
Repressor Proteins1201430200.050 Why?
Ubiquitin-Protein Ligases2202318600.050 Why?
Electrophoresis, Capillary12022640.050 Why?
Coronavirus Infections1202031300.050 Why?
Pneumonia, Viral1202032360.050 Why?
Amino Acid Sequence22016138140.050 Why?
Antigens, Viral, Tumor120221540.050 Why?
Mice, Nude2201936890.050 Why?
Neoplasms32022215960.050 Why?
Thiolester Hydrolases12022860.050 Why?
Proteasome Endopeptidase Complex2202013330.050 Why?
Inflammation Mediators2202218890.050 Why?
Signal Transduction72020233870.050 Why?
Adaptor Proteins, Signal Transducing2202229150.050 Why?
Prognosis12021290100.050 Why?
Molecular Targeted Therapy3201627230.050 Why?
Toll-Like Receptor 2120223540.050 Why?
Biocatalysis120201670.050 Why?
Benzylamines120212260.040 Why?
Ikaros Transcription Factor120212140.040 Why?
Buthionine Sulfoximine12019180.040 Why?
Glutamate-Cysteine Ligase12019250.040 Why?
src-Family Kinases120225510.040 Why?
Adenylyl Imidodiphosphate12019190.040 Why?
Ubiquitinated Proteins12019340.040 Why?
Thiocyanates12019700.040 Why?
Anti-HIV Agents1201542500.040 Why?
Methylation1202211070.040 Why?
Databases, Protein120203830.040 Why?
Cell Line32020159940.040 Why?
Protein Conformation2201940130.040 Why?
Mammary Glands, Human120192000.040 Why?
Enzyme Activation2201437010.040 Why?
Mammary Glands, Animal120192770.040 Why?
Triazines120193160.040 Why?
T-Lymphocytes12015101630.040 Why?
HIV-11201569340.040 Why?
Dimerization120198930.040 Why?
Female620213795920.040 Why?
Drug Resistance, Multiple, Fungal1201670.040 Why?
Aged, 80 and over12021576830.030 Why?
Mice, SCID1202127150.030 Why?
Allosteric Regulation120174080.030 Why?
Dipeptides120184090.030 Why?
Thiourea12016630.030 Why?
Ketoconazole12016950.030 Why?
Peptides, Cyclic120184010.030 Why?
Blotting, Western2201451800.030 Why?
Molecular Sequence Data12009181120.030 Why?
Mitochondrial Proteins120229950.030 Why?
Brain Neoplasms1201788290.030 Why?
Thalidomide120218880.030 Why?
Viral Proteins1202318990.030 Why?
Cytokines2202273170.030 Why?
Proto-Oncogene Proteins c-kit120197740.030 Why?
Nitrofurans1201460.030 Why?
DNA2200772890.030 Why?
Protein Processing, Post-Translational1202319890.030 Why?
Basic Helix-Loop-Helix Transcription Factors1202111140.030 Why?
Hydrazines120162200.030 Why?
Quinazolines1202113550.030 Why?
Pimozide12013210.030 Why?
Protein Interaction Domains and Motifs120164740.030 Why?
Candidiasis120163650.030 Why?
Gene Expression Regulation, Fungal120165020.030 Why?
Tumor Burden1201919050.030 Why?
Fanconi Anemia Complementation Group D2 Protein120131470.030 Why?
Nuclear Magnetic Resonance, Biomolecular120165070.030 Why?
Organoids120196920.030 Why?
Cell Death1201816950.030 Why?
Pyrroles1201911430.030 Why?
Fluorescence Resonance Energy Transfer120154010.030 Why?
Cell Membrane1202237440.030 Why?
Gene Expression Regulation, Leukemic120166510.030 Why?
Models, Chemical120146260.030 Why?
Neoplasm Transplantation1201620850.030 Why?
Sulfones120144370.030 Why?
Biological Assay120156520.030 Why?
Luciferases120137330.020 Why?
Blood-Brain Barrier1201710150.020 Why?
Immunoprecipitation120139050.020 Why?
Calcineurin120112260.020 Why?
Lentivirus120135010.020 Why?
Middle Aged220212131270.020 Why?
Area Under Curve1201416530.020 Why?
Nitriles120149520.020 Why?
Epigenesis, Genetic1202236390.020 Why?
Aged120211629440.020 Why?
Drug Evaluation, Preclinical1201413720.020 Why?
Reproducibility of Results22018198620.020 Why?
Oxidative Stress1201930810.020 Why?
Cell Cycle1201529640.020 Why?
Virus Replication1201525310.020 Why?
Saccharomyces cerevisiae Proteins1201618840.020 Why?
Interleukin-61201631990.020 Why?
Host-Pathogen Interactions1201514770.020 Why?
Binding, Competitive1200711590.020 Why?
RNA, Messenger12020130290.020 Why?
Microbial Sensitivity Tests1201118710.020 Why?
NF-kappa B1201325000.020 Why?
Transcription, Genetic1201877210.010 Why?
RNA, Small Interfering1201335040.010 Why?
Peptide Fragments1201650950.010 Why?
Tumor Suppressor Proteins1201428420.010 Why?
Flow Cytometry1201359750.010 Why?
Pyridines1201428180.010 Why?
Child22023774780.010 Why?
Cell Movement1201452120.010 Why?
HeLa Cells1200731270.010 Why?
Mice, Inbred C57BL12019218210.010 Why?
B-Lymphocytes1201446640.010 Why?
Computational Biology1201335180.010 Why?
Pandemics1202083280.010 Why?
Parkinson Disease1201227740.010 Why?
DNA-Binding Proteins1201696390.010 Why?
HIV Infections12023166780.010 Why?
Gene Expression Regulation12015120710.010 Why?
Male320203495380.010 Why?
Case-Control Studies12013217190.010 Why?
Disease Models, Animal12013180060.010 Why?
Young Adult12020563500.010 Why?
Genetic Predisposition to Disease12012174000.010 Why?
Adult120202137120.000 Why?
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Concepts (276)
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Co-Authors (80)
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.