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John P. Manis, M.D.

Concepts (401)

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Concepts are derived automatically from a person's publications.
Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.
Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Immunoglobulin Class Switching2620172932.960 Why?
B-Lymphocytes36202049131.300 Why?
Immunoglobulin Heavy Chains1720156501.140 Why?
Recombination, Genetic18201117570.980 Why?
Cytidine Deaminase1320152270.930 Why?
Anemia, Sickle Cell520219250.890 Why?
DNA Repair18201520350.800 Why?
Hematopoietic Stem Cells8202134570.780 Why?
Blood Platelets2202224460.720 Why?
Severe Combined Immunodeficiency220152230.630 Why?
DNA Polymerase II120151130.570 Why?
Immunoglobulin Constant Regions42015620.560 Why?
DNA-Binding Proteins24201699340.560 Why?
Transplantation Conditioning1202115140.510 Why?
Platelet Transfusion120162760.510 Why?
gamma-Globins32020860.450 Why?
Genes, Immunoglobulin520032840.440 Why?
DNA Damage12201025070.440 Why?
YY1 Transcription Factor12011660.430 Why?
Chromosome Breakage420081830.430 Why?
Germinal Center320203540.420 Why?
Nuclear Proteins14201960090.410 Why?
Antigens, Nuclear520101990.410 Why?
DNA Breaks, Double-Stranded620155870.400 Why?
B-Lymphocyte Subsets120112470.390 Why?
Immunoglobulin E5201714480.390 Why?
Translocation, Genetic8200814400.390 Why?
Lymphopoiesis320181360.370 Why?
DNA Breaks12008490.360 Why?
Nobel Prize12007500.350 Why?
Mutation162018288480.330 Why?
Mice, Knockout252016155970.330 Why?
Tumor Suppressor Protein p5313200829120.300 Why?
Hematopoietic Stem Cell Transplantation3202148830.290 Why?
Mice582021808030.290 Why?
Immunoglobulin mu-Chains22011680.280 Why?
Lymphoma3201118630.280 Why?
Lymphoma, B-Cell920109000.280 Why?
Genetic Techniques120074520.280 Why?
Toll-Like Receptor 9220172080.260 Why?
STAT3 Transcription Factor320189680.260 Why?
DNA-Activated Protein Kinase520141120.260 Why?
Hypergammaglobulinemia12003770.260 Why?
Immunoglobulin Switch Region42010450.250 Why?
Tumor Suppressor Proteins7201229020.250 Why?
Immunoglobulin M4201014940.250 Why?
Animals6620211708490.240 Why?
Immunologic Deficiency Syndromes320176270.240 Why?
CD8-Positive T-Lymphocytes1201641150.240 Why?
Gene Rearrangement, B-Lymphocyte420081180.240 Why?
Freeze Drying120221010.240 Why?
Mice, Mutant Strains5201620090.240 Why?
Cell Differentiation112018118330.220 Why?
Somatic Hypermutation, Immunoglobulin42007770.220 Why?
Fetal Hemoglobin220203240.220 Why?
Guanine Nucleotide Exchange Factors220175760.220 Why?
DNA Helicases420008360.210 Why?
Intracellular Signaling Peptides and Proteins4200930060.210 Why?
Focal Adhesion Kinase 1220121320.210 Why?
Phosphoproteins3200626450.210 Why?
Repressor Proteins3202030590.200 Why?
Lymphocytes6201728670.200 Why?
Genes, RAG-122018680.200 Why?
Genes, Immunoglobulin Heavy Chain32008590.200 Why?
Hematopoietic Stem Cell Mobilization220182270.200 Why?
Cell Cycle Proteins5201234710.190 Why?
Embryonic Stem Cells1200714320.190 Why?
Reed-Sternberg Cells11999870.190 Why?
DNA Ligases32014840.190 Why?
Protein Phosphatase 2120202200.180 Why?
Blood Component Removal120181140.180 Why?
Histones5201525660.170 Why?
Flow Cytometry10202062300.170 Why?
Immunoglobulin G6201442970.170 Why?
Heterocyclic Compounds120182790.170 Why?
Immunoglobulin Light Chains320052590.170 Why?
Neutropenia120218520.160 Why?
N-Glycosyl Hydrolases12016780.160 Why?
Transmembrane Activator and CAML Interactor Protein12016590.160 Why?
Genomic Instability420166910.160 Why?
Bone Diseases, Developmental120171240.160 Why?
Immunoglobulin epsilon-Chains22014170.160 Why?
Lymphocyte Activation8202059890.150 Why?
Agammaglobulinemia119961650.150 Why?
Bone Marrow2201829010.150 Why?
Endodeoxyribonucleases120161750.150 Why?
Immunoglobulin Isotypes320021590.150 Why?
N-Acetylglucosaminyltransferases120171900.150 Why?
Pneumonia, Pneumococcal120161360.150 Why?
Gene Expression Regulation42018126800.150 Why?
Heterozygote4201627870.140 Why?
Enhancer Elements, Genetic2201913850.140 Why?
Homeodomain Proteins4201625310.140 Why?
Endonucleases520153720.140 Why?
Mice, Transgenic72020100940.140 Why?
T-Lymphocytes72020103290.140 Why?
I-kappa B Proteins120152450.140 Why?
Carrier Proteins4201952570.130 Why?
Pneumococcal Vaccines120184180.130 Why?
Intestinal Atresia12013640.130 Why?
Sequence Deletion4201515850.130 Why?
Organogenesis120152410.130 Why?
Lymphoid Tissue120155020.120 Why?
Pneumococcal Infections120185450.120 Why?
Poly Adenosine Diphosphate Ribose12012570.120 Why?
Serine Endopeptidases1201811350.120 Why?
DNA Nucleotidyltransferases220022000.120 Why?
Cells, Cultured132020206200.120 Why?
Adaptor Proteins, Vesicular Transport120143310.120 Why?
In Situ Hybridization, Fluorescence6200826280.110 Why?
Ubiquitin-Protein Ligases2201218260.110 Why?
Myeloid Differentiation Factor 88220145480.110 Why?
Th17 Cells120187050.110 Why?
5' Flanking Region12010340.110 Why?
Wiskott-Aldrich Syndrome Protein120121640.110 Why?
Hodgkin Disease1199914280.110 Why?
Precursor Cells, B-Lymphoid22010990.110 Why?
RNA Interference1202031030.110 Why?
DNA Mutational Analysis3201544150.110 Why?
Humans4020226866630.110 Why?
Alleles6201871400.110 Why?
Toll-Like Receptor 4120145670.100 Why?
Deoxyribonuclease I120102330.100 Why?
Fatal Outcome1201519390.100 Why?
Genes, Regulator220033890.100 Why?
Neutrophils2202138760.100 Why?
Gene Conversion22016770.100 Why?
Trans-Activators3201231500.100 Why?
Gene Rearrangement, T-Lymphocyte219991200.090 Why?
Mice, Inbred C57BL132018234390.090 Why?
Gene Rearrangement4200312100.090 Why?
Chromosome Aberrations3200717990.090 Why?
Chromosome Pairing12007480.090 Why?
Developmental Disabilities1201714240.090 Why?
Chromatin Immunoprecipitation120119360.090 Why?
Induced Pluripotent Stem Cells2201715320.090 Why?
beta-Thalassemia220202280.090 Why?
Phosphorylation7201588960.080 Why?
Suppressor of Cytokine Signaling Proteins120071770.080 Why?
Regulatory Elements, Transcriptional120071890.080 Why?
Immunoglobulins120109010.080 Why?
Thymus Neoplasms220062380.080 Why?
Chromosomes, Human, Pair 15120073830.080 Why?
VDJ Recombinases22002830.080 Why?
Apoptosis82018102610.080 Why?
Base Sequence82019137290.070 Why?
Immunophenotyping3201819150.070 Why?
Models, Immunological120085420.070 Why?
Lysine1200910360.070 Why?
Autoimmune Diseases1201620920.070 Why?
Serine120098480.070 Why?
Immunologic Memory1201214030.070 Why?
Genes, myc220044030.070 Why?
Mice, SCID2200229130.070 Why?
Models, Genetic2200836020.070 Why?
Receptors, Antigen, B-Cell120075450.070 Why?
Immunoblotting3201418400.070 Why?
Genetic Vectors2202036280.070 Why?
VDJ Exons22015110.070 Why?
Cell Cycle5201430660.070 Why?
Suppression, Genetic120042080.070 Why?
Autoantibodies3202019250.070 Why?
Child, Preschool62017411590.070 Why?
Intestines1201319430.060 Why?
Plasma Cells220105910.060 Why?
Cyclic AMP-Dependent Protein Kinases120055400.060 Why?
Phenotype62018160910.060 Why?
Genes, Switch12002470.060 Why?
Gene Dosage1200712810.060 Why?
Receptors, CXCR4120077370.060 Why?
Leukocyte Transfusion12021590.060 Why?
Interleukin-42201711590.060 Why?
Gene Knock-In Techniques220164670.060 Why?
Genes, p53120047830.060 Why?
Cell Count2201819740.050 Why?
Radiation, Ionizing220152680.050 Why?
History, 21st Century1200715940.050 Why?
Ubiquitination320129960.050 Why?
Cell Transformation, Neoplastic2200830530.050 Why?
Enzyme-Linked Immunosorbent Assay2202040760.050 Why?
Sirtuins120033630.050 Why?
Mice, Inbred BALB C4201467860.050 Why?
beta-Lactamases120023570.050 Why?
Gene Targeting220209370.050 Why?
Ovarian Neoplasms1201646480.050 Why?
Locus Control Region11999270.050 Why?
Granulocyte-Macrophage Colony-Stimulating Factor120039160.050 Why?
Transcription, Genetic3200781300.050 Why?
Neoplasm Proteins1201239720.050 Why?
Proteins2201362640.050 Why?
Transcription Factors32010119100.050 Why?
Granulocyte Colony-Stimulating Factor120216230.050 Why?
Congenital Abnormalities120036990.050 Why?
Lipopolysaccharides2201422490.050 Why?
Fetal Death120004580.040 Why?
Biological Transport, Active219703850.040 Why?
Erythroid Precursor Cells120192350.040 Why?
Lymphoma, Large B-Cell, Diffuse1200712520.040 Why?
INDEL Mutation120192530.040 Why?
DNA Primers3201031210.040 Why?
Antigens, CD34120206720.040 Why?
Genetic Predisposition to Disease22018170710.040 Why?
Neoplasms, Experimental1200414160.040 Why?
Benzylamines120182330.040 Why?
Globins119984520.040 Why?
Cell Line52014171370.040 Why?
Oncogenes1200312120.040 Why?
Gene Amplification1200210940.040 Why?
Syndrome1200331780.040 Why?
Chromatids12016610.040 Why?
Adaptor Proteins, Signal Transducing3201630060.040 Why?
Peripheral Blood Stem Cell Transplantation120182760.040 Why?
Pilot Projects2202077910.040 Why?
Poly I-C120161050.040 Why?
Radiation Tolerance220155580.040 Why?
Cell Division2200249060.040 Why?
Gene Expression Profiling2201196610.040 Why?
Heparitin Sulfate120171930.040 Why?
HeLa Cells2201633950.040 Why?
RNA, Guide120193290.040 Why?
Deamination12015280.040 Why?
Reverse Transcriptase Polymerase Chain Reaction3201451140.040 Why?
RNA, Small Interfering2202037130.040 Why?
Membrane Proteins1201482620.040 Why?
Male1320203524650.040 Why?
Polymerase Chain Reaction3201664640.040 Why?
Oligodeoxyribonucleotides120177700.040 Why?
Oncogene Proteins v-abl12015220.040 Why?
Hybridomas220104540.040 Why?
Chromosomal Proteins, Non-Histone220157470.040 Why?
Zygote120161230.040 Why?
Signal Transduction42014243510.040 Why?
Transplantation, Autologous1202020720.040 Why?
Cell Death1202117690.040 Why?
Cell Survival2201862880.040 Why?
Immunoprecipitation220099690.040 Why?
Gene Knockdown Techniques1202017610.040 Why?
Antibody Formation2201514160.040 Why?
Tumor Necrosis Factors12015860.040 Why?
Amino Acid Sequence32019146560.040 Why?
Mice, Inbred NOD1202019740.040 Why?
Fluorescent Antibody Technique2201227720.040 Why?
Haploinsufficiency120162890.040 Why?
Immunoglobulin gamma-Chains12014330.040 Why?
Genome2200016810.040 Why?
Dermatitis, Contact120151440.030 Why?
Thymus Gland2201313540.030 Why?
Interferon-gamma1200332630.030 Why?
Neoplasms42003195380.030 Why?
Immunity, Humoral120185540.030 Why?
Hypersensitivity, Delayed120155390.030 Why?
Phenylenediamines12014940.030 Why?
Cell Line, Transformed1201510260.030 Why?
Disease Models, Animal42018184950.030 Why?
Mice, 129 Strain120144180.030 Why?
Integrin alpha4beta1120121210.030 Why?
Codon120156270.030 Why?
Receptors, Interleukin120142560.030 Why?
Histone Chaperones12012690.030 Why?
X Chromosome119968900.030 Why?
Colony-Forming Units Assay120123860.030 Why?
Transcription Factor RelA120142900.030 Why?
Focal Adhesion Kinase 212012910.030 Why?
Interleukin-7120121280.030 Why?
Down-Regulation1202032260.030 Why?
Streptococcus pneumoniae120187570.030 Why?
Catalysis120149080.030 Why?
Mutagenesis, Site-Directed1201618580.030 Why?
Lupus Erythematosus, Systemic2202019970.030 Why?
BRCA2 Protein120166610.030 Why?
Autoimmunity1202013090.030 Why?
Cell Proliferation32018109900.030 Why?
Female1220203754590.030 Why?
Intestine, Small2197012810.030 Why?
Tissue Array Analysis120135940.030 Why?
Toll-Like Receptors120155910.030 Why?
Sequence Alignment2200823520.030 Why?
Antigens, CD1200242560.030 Why?
Metal Metabolism, Inborn Errors11970140.030 Why?
Oligonucleotide Array Sequence Analysis2201341290.030 Why?
Common Variable Immunodeficiency12011960.030 Why?
Lymphopenia120122680.030 Why?
Poly(ADP-ribose) Polymerases120124440.030 Why?
Gene Rearrangement, B-Lymphocyte, Heavy Chain12010920.030 Why?
Disease Susceptibility1201818120.030 Why?
Rodent Diseases11970760.030 Why?
Fibroblasts3201443450.030 Why?
Chemokine CXCL12120124680.030 Why?
Genetic Linkage1199626000.030 Why?
Feasibility Studies1202048070.030 Why?
BRCA1 Protein120169950.030 Why?
Iron2197016690.030 Why?
Breast Neoplasms12016191530.020 Why?
Chemotaxis, Leukocyte120127170.020 Why?
Blotting, Southern120108470.020 Why?
Infant32017339180.020 Why?
src-Family Kinases120125780.020 Why?
Hematopoiesis1201819610.020 Why?
Peyer's Patches120091210.020 Why?
Active Transport, Cell Nucleus120104690.020 Why?
Adolescent42020849570.020 Why?
Hydroxyurea120092900.020 Why?
Molecular Sequence Data32008193280.020 Why?
Young Adult32020560520.020 Why?
Autoantigens120129140.020 Why?
Enzyme Induction120075170.020 Why?
Duodenum219705040.020 Why?
Regulatory Sequences, Nucleic Acid120107840.020 Why?
Phenylhydrazines11966320.020 Why?
Methylation1200911260.020 Why?
Immunohistochemistry22014120950.020 Why?
HEK293 Cells1201644160.020 Why?
Nucleosomes120094590.020 Why?
Acetylation1200911400.020 Why?
Inflammation2200396170.020 Why?
Microscopy, Fluorescence1201429230.020 Why?
T-Lymphocyte Subsets1201519140.020 Why?
Replication Protein A12005690.020 Why?
Recombinant Proteins2200970600.020 Why?
Chromosomes, Mammalian120061470.020 Why?
Zebrafish1201729690.020 Why?
Dose-Response Relationship, Drug12018116160.020 Why?
Histone-Lysine N-Methyltransferase120096920.020 Why?
Vascular Cell Adhesion Molecule-1120077270.020 Why?
Survival Rate32006136060.020 Why?
Child32020713610.020 Why?
Proto-Oncogene Proteins c-akt1201425680.020 Why?
Protein Structure, Tertiary1201241840.020 Why?
Protein Binding2200999470.020 Why?
Ubiquitin120098550.020 Why?
Infant, Newborn22015239530.020 Why?
Cell Lineage1201426760.020 Why?
Analysis of Variance1201466850.020 Why?
Metformin120107400.020 Why?
Leukemia, B-Cell12004790.020 Why?
Neurons2200093310.020 Why?
Sirtuin 2120031170.020 Why?
RNA, Messenger22013134690.020 Why?
Doxorubicin1200922490.020 Why?
Proto-Oncogene Proteins c-myc1200810420.020 Why?
Cytosol120069420.020 Why?
Infertility, Male120064190.010 Why?
Exons1200925190.010 Why?
Infrared Rays120032610.010 Why?
Telomere120077970.010 Why?
Anemia1197013570.010 Why?
Erythropoiesis119667160.010 Why?
Restriction Mapping120029390.010 Why?
Case-Control Studies12020216840.010 Why?
Sialoglycoproteins120023840.010 Why?
Homeostasis1201232970.010 Why?
Genotype22010130730.010 Why?
Karyotyping1200312800.010 Why?
Binding Sites1201064990.010 Why?
Biological Evolution1200710860.010 Why?
Protein Processing, Post-Translational1200921110.010 Why?
Polyomavirus120012490.010 Why?
Cell Adhesion1200733850.010 Why?
Chimera120015040.010 Why?
Phosphoglycerate Kinase11999630.010 Why?
Neomycin11999870.010 Why?
Adult320202114000.010 Why?
Chromosomes120025780.010 Why?
Genes, Lethal120002680.010 Why?
Genes, Tumor Suppressor1200411110.010 Why?
Homozygote1200418550.010 Why?
Receptors, Antigen, T-Cell, alpha-beta120028070.010 Why?
Transfection1200763290.010 Why?
Proto-Oncogene Proteins1201047160.010 Why?
Cyclin-Dependent Kinase Inhibitor p16120007440.010 Why?
Gene Expression1201081820.010 Why?
Growth119994350.010 Why?
Gene Expression Regulation, Neoplastic2200488950.010 Why?
Antibodies, Monoclonal1201498630.010 Why?
Mutagenesis, Insertional119996740.010 Why?
Antigens1200114960.010 Why?
Cloning, Molecular1200246710.010 Why?
Nervous System119995660.010 Why?
Chromosome Mapping1200449520.010 Why?
Fetal Growth Retardation119975410.010 Why?
Life Expectancy1200011050.010 Why?
Embryo, Mammalian1200018430.010 Why?
Cell Line, Tumor12010172510.010 Why?
Chromatin1200325030.010 Why?
Gene Deletion1200029220.010 Why?
Iron Isotopes11970180.010 Why?
Serous Membrane11970290.010 Why?
Haploidy119701510.010 Why?
Sex Chromosomes119701010.010 Why?
Stem Cells1200236120.010 Why?
Aged120211622710.010 Why?
Models, Biological12006101020.010 Why?
Polymorphism, Single Nucleotide12007152960.010 Why?
Dactinomycin119663400.000 Why?
Arthritis, Rheumatoid1200134920.000 Why?
Leucine119665960.000 Why?
Ferritins119665550.000 Why?
DNA1197073200.000 Why?
Rats21966253070.000 Why?
Liver1196676530.000 Why?
Carbon Isotopes119665290.000 Why?
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© 2022 President and Fellows of Harvard College
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.