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John P. Manis, M.D.

Concepts (425)

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Concepts are derived automatically from a person's publications.
Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.
Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Immunoglobulin Class Switching2620172892.540 Why?
B-Lymphocytes37202447481.240 Why?
Immunoglobulin Heavy Chains1720156490.970 Why?
Recombination, Genetic18201115260.900 Why?
Anemia, Sickle Cell6202410630.840 Why?
Hematopoietic Stem Cells9202433960.790 Why?
Cytidine Deaminase1320152450.780 Why?
DNA Repair18201520440.710 Why?
Blood Platelets2202224780.620 Why?
Severe Combined Immunodeficiency220152260.530 Why?
DNA-Binding Proteins24201695980.510 Why?
DNA Polymerase II120151040.490 Why?
Immunoglobulin Constant Regions42015580.470 Why?
Transplantation Conditioning1202115880.450 Why?
Platelet Transfusion120162970.430 Why?
gamma-Globins42022990.420 Why?
Nuclear Proteins15202257940.390 Why?
DNA Damage12201024410.390 Why?
Lymphoma, B-Cell1020249400.370 Why?
Genes, Immunoglobulin520032850.370 Why?
Chromosome Breakage420081590.370 Why?
YY1 Transcription Factor12011590.370 Why?
Germinal Center320203800.350 Why?
Fetal Hemoglobin320223450.350 Why?
Antigens, Nuclear520101840.340 Why?
Translocation, Genetic8200813880.340 Why?
DNA Breaks, Double-Stranded620156120.340 Why?
B-Lymphocyte Subsets120112390.330 Why?
Immunoglobulin E5201714940.330 Why?
Lymphopoiesis320181330.310 Why?
DNA Breaks12008470.300 Why?
Mutation172024300250.300 Why?
Hematopoietic Stem Cell Transplantation4202456630.290 Why?
Mice, Knockout252016143970.290 Why?
Nobel Prize12007480.290 Why?
Mice622024814020.280 Why?
Tumor Suppressor Protein p5313200829110.260 Why?
Genetic Techniques120074270.240 Why?
Immunoglobulin mu-Chains22011620.240 Why?
STAT3 Transcription Factor320188700.240 Why?
Lymphoma3201119010.240 Why?
Animals7020241682530.240 Why?
Tumor Suppressor Proteins7201228030.220 Why?
Toll-Like Receptor 9220172330.220 Why?
DNA-Activated Protein Kinase520141120.220 Why?
Hypergammaglobulinemia12003720.220 Why?
Erythroblastosis, Fetal12023620.220 Why?
Immunologic Deficiency Syndromes320175570.210 Why?
Mice, Mutant Strains5201617510.210 Why?
Immunoglobulin Switch Region42010450.210 Why?
Immunoglobulin M4201015300.210 Why?
Repressor Proteins4202229780.210 Why?
Gene Rearrangement, B-Lymphocyte420081120.200 Why?
CD8-Positive T-Lymphocytes1201645750.200 Why?
Cell Differentiation112018115260.200 Why?
Freeze Drying120221010.200 Why?
Hemoglobinopathies12022990.190 Why?
Intracellular Signaling Peptides and Proteins4200928700.190 Why?
Phosphoproteins3200624440.190 Why?
Guanine Nucleotide Exchange Factors220175690.190 Why?
DNA Helicases420008510.190 Why?
Somatic Hypermutation, Immunoglobulin420071010.180 Why?
Lymphocytes6201726100.180 Why?
Embryonic Stem Cells1200712620.180 Why?
Focal Adhesion Kinase 1220121190.180 Why?
Cell Cycle Proteins5201234460.170 Why?
Hematopoietic Stem Cell Mobilization220182250.170 Why?
Genes, RAG-122018670.170 Why?
Genes, Immunoglobulin Heavy Chain32008570.170 Why?
Reed-Sternberg Cells11999720.160 Why?
DNA Ligases32014820.160 Why?
Flow Cytometry10202058650.150 Why?
Protein Phosphatase 2120202310.150 Why?
Histones5201525770.150 Why?
Blood Component Removal120181320.150 Why?
Heterocyclic Compounds120182460.140 Why?
Carrier Proteins5202249360.140 Why?
HIV Seropositivity120229600.140 Why?
Immunoglobulin G6201445490.140 Why?
Lymphocyte Activation8202054910.140 Why?
Immunoglobulin Light Chains320052860.140 Why?
N-Glycosyl Hydrolases12016680.140 Why?
Genomic Instability420167090.140 Why?
Gene Expression Regulation42018119000.140 Why?
Transmembrane Activator and CAML Interactor Protein12016550.130 Why?
Neutropenia120218840.130 Why?
Bone Diseases, Developmental120171310.130 Why?
Immunoglobulin epsilon-Chains22014160.130 Why?
Bone Marrow2201829070.130 Why?
N-Acetylglucosaminyltransferases120171660.130 Why?
Homeodomain Proteins4201624130.130 Why?
Endodeoxyribonucleases120161640.130 Why?
Immunoglobulin Isotypes320021580.120 Why?
Pneumonia, Pneumococcal120161310.120 Why?
Heterozygote4201627980.120 Why?
Enhancer Elements, Genetic2201913630.120 Why?
Agammaglobulinemia119961730.120 Why?
Mice, Transgenic7202095330.120 Why?
Endonucleases520153690.120 Why?
T-Lymphocytes72020101880.120 Why?
Pneumococcal Vaccines120183970.120 Why?
I-kappa B Proteins120152110.120 Why?
Erythrocytes1202324170.110 Why?
Vaccines120228360.110 Why?
Sequence Deletion4201514940.110 Why?
Organogenesis120152150.110 Why?
Serine Endopeptidases1201810210.110 Why?
Pneumococcal Infections120185020.110 Why?
Cells, Cultured132020189550.110 Why?
Lymphoid Tissue120154450.110 Why?
Intestinal Atresia12013680.110 Why?
Poly Adenosine Diphosphate Ribose12012500.100 Why?
In Situ Hybridization, Fluorescence6200825090.100 Why?
Adaptor Proteins, Vesicular Transport120143060.100 Why?
Humans4520247604370.100 Why?
DNA Nucleotidyltransferases220021760.100 Why?
RNA Interference1202028320.100 Why?
DNA Mutational Analysis3201541080.100 Why?
Ubiquitin-Protein Ligases2201218890.100 Why?
Alleles6201869080.100 Why?
Th17 Cells120187920.100 Why?
Myeloid Differentiation Factor 88220145860.090 Why?
Hodgkin Disease1199913780.090 Why?
Wiskott-Aldrich Syndrome Protein120121600.090 Why?
5' Flanking Region12010310.090 Why?
Precursor Cells, B-Lymphoid22010990.090 Why?
Genetic Vectors3202433920.090 Why?
Trans-Activators3201228580.090 Why?
Fatal Outcome1201518320.090 Why?
Lentivirus220245080.090 Why?
Neutrophils2202137640.090 Why?
Toll-Like Receptor 4120145790.090 Why?
Antigens, CD34220246580.090 Why?
Deoxyribonuclease I120102240.090 Why?
Genes, Regulator220033740.090 Why?
Gene Conversion22016670.080 Why?
Gene Rearrangement4200311250.080 Why?
Mice, Inbred C57BL132018221210.080 Why?
Chromosome Aberrations3200717710.080 Why?
Gene Rearrangement, T-Lymphocyte219991110.080 Why?
Chromatin Immunoprecipitation120118550.080 Why?
Developmental Disabilities1201715080.070 Why?
Chromosome Pairing12007450.070 Why?
Phosphorylation7201583110.070 Why?
beta-Thalassemia220202360.070 Why?
Base Sequence82019124490.070 Why?
Apoptosis8201894680.070 Why?
Suppressor of Cytokine Signaling Proteins120071780.070 Why?
Immunoglobulins120108590.070 Why?
Regulatory Elements, Transcriptional120071830.070 Why?
Induced Pluripotent Stem Cells2201718570.070 Why?
Chromosomes, Human, Pair 15120073610.070 Why?
VDJ Recombinases22002840.060 Why?
Models, Immunological120085120.060 Why?
Immunophenotyping3201818700.060 Why?
Immunologic Memory1201213590.060 Why?
Aging1202486890.060 Why?
HIV-11202268590.060 Why?
Thymus Neoplasms220062730.060 Why?
Mice, SCID2200226250.060 Why?
Models, Genetic2200834450.060 Why?
Serine120098280.060 Why?
Lysine120099920.060 Why?
Immunoblotting3201416470.060 Why?
Genes, myc220043900.060 Why?
Cell Cycle5201429290.060 Why?
Receptors, Antigen, B-Cell120075450.060 Why?
Autoimmune Diseases1201622470.060 Why?
Intestines1201319090.060 Why?
Child, Preschool62017422090.060 Why?
Rho(D) Immune Globulin12023340.060 Why?
Suppression, Genetic120041900.060 Why?
VDJ Exons22015110.060 Why?
Autoantibodies3202021230.060 Why?
Plasma Cells220105990.050 Why?
Cyclic AMP-Dependent Protein Kinases120054830.050 Why?
DNA Nucleotidylexotransferase12022640.050 Why?
Proto-Oncogene Proteins c-myc220249880.050 Why?
Transcription Factors42022121210.050 Why?
Gene Dosage1200712180.050 Why?
Receptors, CXCR4120077270.050 Why?
Phenotype62018165850.050 Why?
Complementarity Determining Regions120221490.050 Why?
Genes, Switch12002480.050 Why?
Interleukin-42201711300.050 Why?
Leukocyte Transfusion12021560.050 Why?
Transduction, Genetic120249010.050 Why?
Gene Knock-In Techniques220164210.050 Why?
Cell Transformation, Neoplastic2200828210.050 Why?
Genes, p53120047120.050 Why?
Cell Count2201818340.050 Why?
History, 21st Century1200715670.050 Why?
Ubiquitination3201210060.050 Why?
Isoantigens120235520.050 Why?
Enzyme-Linked Immunosorbent Assay2202038000.050 Why?
Radiation, Ionizing220152510.050 Why?
Mice, Inbred BALB C4201462060.050 Why?
Clone Cells1202416600.050 Why?
beta-Lactamases120023050.040 Why?
Sirtuins120033200.040 Why?
Gene Targeting220208380.040 Why?
Neoplasm Proteins1201236100.040 Why?
Transcription, Genetic3200775970.040 Why?
Isoantibodies120236740.040 Why?
Ovarian Neoplasms1201648790.040 Why?
Proteins2201360330.040 Why?
Granulocyte-Macrophage Colony-Stimulating Factor120038910.040 Why?
Locus Control Region11999210.040 Why?
DNA Primers3201028200.040 Why?
Neoplasms, Experimental1200412280.040 Why?
Lipopolysaccharides2201422050.040 Why?
Cell Line52014155980.040 Why?
Granulocyte Colony-Stimulating Factor120216290.040 Why?
Congenital Abnormalities120037060.040 Why?
Erythroid Precursor Cells120192110.040 Why?
Fetal Death120004350.040 Why?
Genetic Predisposition to Disease22018178540.040 Why?
Biological Transport, Active219703280.040 Why?
INDEL Mutation120192670.040 Why?
Globins119984030.040 Why?
Gene Amplification1200210860.040 Why?
Adaptor Proteins, Signal Transducing3201628950.040 Why?
Oncogenes1200312230.040 Why?
Benzylamines120182470.040 Why?
Reverse Transcriptase Polymerase Chain Reaction3201445670.040 Why?
Gene Expression Profiling2201194100.040 Why?
Cell Division2200244610.040 Why?
HeLa Cells2201630970.040 Why?
Lymphoma, Large B-Cell, Diffuse1200714050.040 Why?
Radiation Tolerance220154790.040 Why?
Membrane Proteins1201478490.040 Why?
Peripheral Blood Stem Cell Transplantation120182630.040 Why?
RNA, Small Interfering2202034280.030 Why?
Syndrome1200332670.030 Why?
Polymerase Chain Reaction3201660860.030 Why?
Chromatids12016620.030 Why?
Signal Transduction42014233970.030 Why?
Poly I-C120161120.030 Why?
Indoles1202418330.030 Why?
Cell Survival2201857900.030 Why?
Amino Acid Sequence32019134450.030 Why?
Male1320203600350.030 Why?
Pilot Projects2202086110.030 Why?
Chromosomal Proteins, Non-Histone220157260.030 Why?
HIV Infections12022173280.030 Why?
Gene Knockdown Techniques1202016100.030 Why?
Deamination12015250.030 Why?
Cell Death1202116640.030 Why?
HIV Antibodies1202213020.030 Why?
Immunoprecipitation220098770.030 Why?
Heparitin Sulfate120172230.030 Why?
Transplantation, Autologous1202021130.030 Why?
Oncogene Proteins v-abl12015190.030 Why?
Mice, Inbred NOD1202018240.030 Why?
Zygote120161150.030 Why?
Hybridomas220104420.030 Why?
Fluorescent Antibody Technique2201224680.030 Why?
Oligodeoxyribonucleotides120177790.030 Why?
Antibodies1202324210.030 Why?
TOR Serine-Threonine Kinases1202420580.030 Why?
Antibody Formation2201513970.030 Why?
Tumor Necrosis Factors120151070.030 Why?
Genome2200017390.030 Why?
Interferon-gamma1200331570.030 Why?
Haploinsufficiency120163290.030 Why?
Thymus Gland2201312410.030 Why?
Dermatitis, Contact120151330.030 Why?
Immunoglobulin gamma-Chains12014330.030 Why?
Immune Tolerance1202323000.030 Why?
Immunity, Humoral120186040.030 Why?
Hypersensitivity, Delayed120154900.030 Why?
Cell Line, Transformed120158680.030 Why?
Female1320233918750.030 Why?
Phenylenediamines12014870.030 Why?
Infant, Newborn32023262800.030 Why?
Disease Models, Animal42018182160.030 Why?
Down-Regulation1202029110.030 Why?
Mice, 129 Strain120143710.030 Why?
X Chromosome119968160.030 Why?
Neoplasms42003220830.030 Why?
Antibodies, Neutralizing1202219420.030 Why?
Codon120156020.030 Why?
Transcription Factor RelA120142530.030 Why?
Receptors, Interleukin120142430.030 Why?
Cell Proliferation32018104250.030 Why?
Integrin alpha4beta1120121190.030 Why?
Mutagenesis, Site-Directed1201616930.030 Why?
Colony-Forming Units Assay120123520.030 Why?
Streptococcus pneumoniae120187310.030 Why?
Catalysis120147740.030 Why?
Histone Chaperones12012820.030 Why?
Pyrimidines1202430240.030 Why?
Interleukin-7120121420.030 Why?
Focal Adhesion Kinase 212012870.030 Why?
Intestine, Small2197012050.020 Why?
Oligonucleotide Array Sequence Analysis2201337770.020 Why?
Antigens, CD1200240000.020 Why?
Sequence Alignment2200821800.020 Why?
Autoimmunity1202013550.020 Why?
BRCA2 Protein120167990.020 Why?
Tissue Array Analysis120135500.020 Why?
Fibroblasts3201441060.020 Why?
Toll-Like Receptors120155890.020 Why?
Lupus Erythematosus, Systemic2202021630.020 Why?
Disease Susceptibility1201817900.020 Why?
Genetic Linkage1199623820.020 Why?
Epigenesis, Genetic1202437820.020 Why?
Metal Metabolism, Inborn Errors11970140.020 Why?
Poly(ADP-ribose) Polymerases120124270.020 Why?
Gene Rearrangement, B-Lymphocyte, Heavy Chain12010910.020 Why?
Chemokine CXCL12120124540.020 Why?
Common Variable Immunodeficiency120111020.020 Why?
Rodent Diseases11970530.020 Why?
Lymphopenia120122800.020 Why?
DNA Methylation1202443830.020 Why?
BRCA1 Protein1201611460.020 Why?
Chemotaxis, Leukocyte120126640.020 Why?
Iron2197017870.020 Why?
src-Family Kinases120125350.020 Why?
Blotting, Southern120107800.020 Why?
Breast Neoplasms12016209850.020 Why?
Hematopoiesis1201820490.020 Why?
Active Transport, Cell Nucleus120104350.020 Why?
Feasibility Studies1202052360.020 Why?
Infant32017361830.020 Why?
Molecular Sequence Data32008176390.020 Why?
Peyer's Patches120091190.020 Why?
Adolescent42020881960.020 Why?
Hydroxyurea120092820.020 Why?
Autoantigens120128760.020 Why?
Immunohistochemistry22014110700.020 Why?
Young Adult32020590680.020 Why?
Enzyme Induction120074510.020 Why?
HEK293 Cells1201642770.020 Why?
Duodenum219704890.020 Why?
Regulatory Sequences, Nucleic Acid120107900.020 Why?
Microscopy, Fluorescence1201426470.020 Why?
Acetylation1200910540.020 Why?
Methylation1200910820.020 Why?
T-Lymphocyte Subsets1201518050.020 Why?
Recombinant Proteins2200965250.020 Why?
Phenylhydrazines11966280.020 Why?
Dose-Response Relationship, Drug12018107590.020 Why?
Inflammation22003107460.020 Why?
Survival Rate32006126980.020 Why?
Nucleosomes120094840.020 Why?
Replication Protein A12005520.020 Why?
Protein Structure, Tertiary1201237920.020 Why?
Chromosomes, Mammalian120061470.020 Why?
Analysis of Variance1201462300.020 Why?
Protein Binding2200993400.020 Why?
Zebrafish1201730020.020 Why?
Proto-Oncogene Proteins c-akt1201424530.020 Why?
Cell Lineage1201425390.020 Why?
Histone-Lysine N-Methyltransferase120096820.020 Why?
Vascular Cell Adhesion Molecule-1120076910.020 Why?
Ubiquitin120098380.010 Why?
Neurons2200094430.010 Why?
Child32020800860.010 Why?
Leukemia, B-Cell12004840.010 Why?
RNA, Messenger22013127850.010 Why?
Sirtuin 212003950.010 Why?
Exons1200923920.010 Why?
Doxorubicin1200922150.010 Why?
Cytosol120068880.010 Why?
Metformin120109050.010 Why?
Infertility, Male120063960.010 Why?
Erythropoiesis119666820.010 Why?
Infrared Rays120032470.010 Why?
Case-Control Studies12020220970.010 Why?
Binding Sites1201060420.010 Why?
Restriction Mapping120028530.010 Why?
Sialoglycoproteins120023150.010 Why?
Genotype22010129760.010 Why?
Homeostasis1201233200.010 Why?
Protein Processing, Post-Translational1200919740.010 Why?
Karyotyping1200311710.010 Why?
Telomere120079310.010 Why?
Cell Adhesion1200730880.010 Why?
Biological Evolution1200710730.010 Why?
Anemia1197015080.010 Why?
Polyomavirus120012340.010 Why?
Chimera120014530.010 Why?
Genes, Tumor Suppressor1200410620.010 Why?
Transfection1200757760.010 Why?
Adult320202207810.010 Why?
Genes, Lethal120002250.010 Why?
Phosphoglycerate Kinase11999660.010 Why?
Homozygote1200417940.010 Why?
Neomycin11999930.010 Why?
Chromosomes120025770.010 Why?
Receptors, Antigen, T-Cell, alpha-beta120028000.010 Why?
Proto-Oncogene Proteins1201045090.010 Why?
Gene Expression1201075820.010 Why?
Gene Expression Regulation, Neoplastic2200485190.010 Why?
Antibodies, Monoclonal1201491760.010 Why?
Cyclin-Dependent Kinase Inhibitor p16120006960.010 Why?
Growth119993650.010 Why?
Cloning, Molecular1200241740.010 Why?
Mutagenesis, Insertional119996560.010 Why?
Antigens1200114460.010 Why?
Chromosome Mapping1200446300.010 Why?
Nervous System119995430.010 Why?
Embryo, Mammalian1200016740.010 Why?
Cell Line, Tumor12010169450.010 Why?
Fetal Growth Retardation119975790.010 Why?
Life Expectancy1200012400.010 Why?
Gene Deletion1200026670.010 Why?
Chromatin1200329510.010 Why?
Iron Isotopes11970190.010 Why?
Serous Membrane11970240.010 Why?
Haploidy119701330.010 Why?
Sex Chromosomes119701020.010 Why?
Stem Cells1200235220.010 Why?
Models, Biological1200694620.010 Why?
Aged120211688400.000 Why?
Polymorphism, Single Nucleotide12007158670.000 Why?
Dactinomycin119663040.000 Why?
Arthritis, Rheumatoid1200137590.000 Why?
Leucine119665480.000 Why?
Ferritins119665970.000 Why?
DNA1197072080.000 Why?
Rats21966237120.000 Why?
Liver1196675310.000 Why?
Carbon Isotopes119664580.000 Why?
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© 2024 President and Fellows of Harvard College
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.