Harvard Catalyst Profiles

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John P. Manis, M.D.

Concepts (417)

Concepts are derived automatically from a person's publications.
Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.
Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Immunoglobulin Class Switching2620172912.640 Why?
B-Lymphocytes36202046651.200 Why?
Immunoglobulin Heavy Chains1720156591.010 Why?
Recombination, Genetic18201115860.920 Why?
Cytidine Deaminase1320152520.800 Why?
Anemia, Sickle Cell5202110180.750 Why?
DNA Repair18201520460.740 Why?
Hematopoietic Stem Cells8202133860.720 Why?
Blood Platelets2202225080.640 Why?
Severe Combined Immunodeficiency220152230.550 Why?
DNA-Binding Proteins24201696480.520 Why?
DNA Polymerase II120151070.510 Why?
Immunoglobulin Constant Regions42015590.490 Why?
Transplantation Conditioning1202115980.470 Why?
gamma-Globins42022950.440 Why?
Platelet Transfusion120163140.440 Why?
DNA Damage12201024320.410 Why?
Nuclear Proteins15202258530.400 Why?
Genes, Immunoglobulin520032910.390 Why?
Chromosome Breakage420081730.380 Why?
YY1 Transcription Factor12011600.380 Why?
Germinal Center320203770.370 Why?
Fetal Hemoglobin320223410.370 Why?
Antigens, Nuclear520101920.360 Why?
DNA Breaks, Double-Stranded620155940.350 Why?
Translocation, Genetic8200814200.350 Why?
Immunoglobulin E5201714630.350 Why?
B-Lymphocyte Subsets120112460.350 Why?
Lymphopoiesis320181350.330 Why?
DNA Breaks12008490.320 Why?
Mice, Knockout252016145570.310 Why?
Mutation162018297860.310 Why?
Nobel Prize12007490.300 Why?
Mice602022811830.280 Why?
Tumor Suppressor Protein p5313200829480.280 Why?
Lymphoma3201118770.250 Why?
Immunoglobulin mu-Chains22011620.250 Why?
Genetic Techniques120074350.250 Why?
STAT3 Transcription Factor320188730.250 Why?
Hematopoietic Stem Cell Transplantation3202154420.240 Why?
Lymphoma, B-Cell920109310.240 Why?
Toll-Like Receptor 9220172120.230 Why?
Animals6820221687570.230 Why?
Tumor Suppressor Proteins7201228490.230 Why?
DNA-Activated Protein Kinase520141170.230 Why?
Hypergammaglobulinemia12003740.230 Why?
Erythroblastosis, Fetal12023600.230 Why?
Immunologic Deficiency Syndromes320175470.220 Why?
Immunoglobulin Switch Region42010460.220 Why?
Immunoglobulin M4201015370.220 Why?
Mice, Mutant Strains5201618660.220 Why?
CD8-Positive T-Lymphocytes1201644790.210 Why?
Gene Rearrangement, B-Lymphocyte420081110.210 Why?
Repressor Proteins4202230230.210 Why?
Cell Differentiation112018114830.210 Why?
Freeze Drying12022980.210 Why?
Hemoglobinopathies12022960.200 Why?
Phosphoproteins3200624400.200 Why?
Intracellular Signaling Peptides and Proteins4200929150.190 Why?
Guanine Nucleotide Exchange Factors220175810.190 Why?
DNA Helicases420008590.190 Why?
Somatic Hypermutation, Immunoglobulin42007970.190 Why?
Lymphocytes6201726170.190 Why?
Focal Adhesion Kinase 1220121200.180 Why?
Embryonic Stem Cells1200712940.180 Why?
Cell Cycle Proteins5201234620.180 Why?
Hematopoietic Stem Cell Mobilization220182270.180 Why?
Genes, RAG-122018680.180 Why?
Genes, Immunoglobulin Heavy Chain32008570.170 Why?
Reed-Sternberg Cells11999730.170 Why?
DNA Ligases32014800.170 Why?
Protein Phosphatase 2120202290.160 Why?
Flow Cytometry10202059740.160 Why?
Blood Component Removal120181250.150 Why?
Histones5201525990.150 Why?
Heterocyclic Compounds120182490.150 Why?
Immunoglobulin G6201445600.150 Why?
Lymphocyte Activation8202055240.150 Why?
HIV Seropositivity120229710.150 Why?
Immunoglobulin Light Chains320052770.150 Why?
Carrier Proteins5202250210.140 Why?
N-Glycosyl Hydrolases12016680.140 Why?
Genomic Instability420166950.140 Why?
Transmembrane Activator and CAML Interactor Protein12016560.140 Why?
Gene Expression Regulation42018120720.140 Why?
Neutropenia120218950.140 Why?
Bone Diseases, Developmental120171300.140 Why?
Immunoglobulin epsilon-Chains22014160.140 Why?
N-Acetylglucosaminyltransferases120171710.130 Why?
Bone Marrow2201829480.130 Why?
Endodeoxyribonucleases120161650.130 Why?
Homeodomain Proteins4201624210.130 Why?
Immunoglobulin Isotypes320021580.130 Why?
Pneumonia, Pneumococcal120161270.130 Why?
Heterozygote4201628040.130 Why?
Agammaglobulinemia119961670.130 Why?
Enhancer Elements, Genetic2201913410.130 Why?
Mice, Transgenic7202097340.130 Why?
Endonucleases520153800.130 Why?
T-Lymphocytes72020101800.120 Why?
Pneumococcal Vaccines120183910.120 Why?
I-kappa B Proteins120152250.120 Why?
Vaccines120228220.120 Why?
Erythrocytes1202324550.120 Why?
Sequence Deletion4201515260.120 Why?
Pneumococcal Infections120184970.110 Why?
Organogenesis120152220.110 Why?
Lymphoid Tissue120154550.110 Why?
Intestinal Atresia12013680.110 Why?
Serine Endopeptidases1201810720.110 Why?
Cells, Cultured132020192290.110 Why?
Poly Adenosine Diphosphate Ribose12012490.110 Why?
DNA Nucleotidyltransferases220021930.100 Why?
Adaptor Proteins, Vesicular Transport120143150.100 Why?
In Situ Hybridization, Fluorescence6200826490.100 Why?
RNA Interference1202028890.100 Why?
Ubiquitin-Protein Ligases2201218610.100 Why?
DNA Mutational Analysis3201541860.100 Why?
Th17 Cells120187660.100 Why?
Alleles6201869330.100 Why?
Myeloid Differentiation Factor 88220145710.100 Why?
Humans4320237443430.100 Why?
Wiskott-Aldrich Syndrome Protein120121600.100 Why?
5' Flanking Region12010310.100 Why?
Hodgkin Disease1199914150.100 Why?
Precursor Cells, B-Lymphoid22010980.100 Why?
Fatal Outcome1201518500.090 Why?
Neutrophils2202137190.090 Why?
Trans-Activators3201229240.090 Why?
Toll-Like Receptor 4120145650.090 Why?
Deoxyribonuclease I120102290.090 Why?
Genes, Regulator220033780.090 Why?
Gene Conversion22016710.090 Why?
Mice, Inbred C57BL132018218270.090 Why?
Gene Rearrangement4200311790.080 Why?
Chromosome Aberrations3200718130.080 Why?
Gene Rearrangement, T-Lymphocyte219991130.080 Why?
Developmental Disabilities1201714560.080 Why?
Chromatin Immunoprecipitation120118930.080 Why?
Chromosome Pairing12007470.080 Why?
Phosphorylation7201584360.080 Why?
beta-Thalassemia220202250.070 Why?
Suppressor of Cytokine Signaling Proteins120071750.070 Why?
Apoptosis8201897270.070 Why?
Base Sequence82019127970.070 Why?
Induced Pluripotent Stem Cells2201717360.070 Why?
Regulatory Elements, Transcriptional120071860.070 Why?
Immunoglobulins120108810.070 Why?
Chromosomes, Human, Pair 15120073730.070 Why?
VDJ Recombinases22002840.070 Why?
Immunophenotyping3201818800.070 Why?
Models, Immunological120085270.070 Why?
Immunologic Memory1201213480.060 Why?
Thymus Neoplasms220062680.060 Why?
Serine120098260.060 Why?
HIV-11202269390.060 Why?
Mice, SCID2200227160.060 Why?
Genetic Vectors2202034200.060 Why?
Lysine1200910070.060 Why?
Models, Genetic2200834940.060 Why?
Immunoblotting3201416820.060 Why?
Autoimmune Diseases1201621330.060 Why?
Genes, myc220043990.060 Why?
Receptors, Antigen, B-Cell120075480.060 Why?
Cell Cycle5201429670.060 Why?
Child, Preschool62017410060.060 Why?
Intestines1201319240.060 Why?
Autoantibodies3202020350.060 Why?
Rho(D) Immune Globulin12023340.060 Why?
VDJ Exons22015110.060 Why?
Suppression, Genetic120041960.060 Why?
Plasma Cells220105910.060 Why?
Cyclic AMP-Dependent Protein Kinases120054910.060 Why?
DNA Nucleotidylexotransferase12022640.060 Why?
Transcription Factors42022122080.050 Why?
Phenotype62018163650.050 Why?
Receptors, CXCR4120077260.050 Why?
Gene Dosage1200712520.050 Why?
Complementarity Determining Regions120221490.050 Why?
Genes, Switch12002470.050 Why?
Interleukin-42201711470.050 Why?
Gene Knock-In Techniques220164180.050 Why?
Leukocyte Transfusion12021600.050 Why?
History, 21st Century1200715340.050 Why?
Genes, p53120047550.050 Why?
Cell Count2201818560.050 Why?
Ubiquitination3201210120.050 Why?
Cell Transformation, Neoplastic2200829420.050 Why?
Enzyme-Linked Immunosorbent Assay2202038700.050 Why?
Isoantigens120235670.050 Why?
Radiation, Ionizing220152580.050 Why?
Mice, Inbred BALB C4201463860.050 Why?
beta-Lactamases120023060.050 Why?
Sirtuins120033230.050 Why?
Gene Targeting220208800.050 Why?
Transcription, Genetic3200777220.050 Why?
Neoplasm Proteins1201237030.050 Why?
Ovarian Neoplasms1201648380.040 Why?
Granulocyte-Macrophage Colony-Stimulating Factor120039030.040 Why?
Isoantibodies120236790.040 Why?
Locus Control Region11999200.040 Why?
Proteins2201361030.040 Why?
Lentivirus120225010.040 Why?
Lipopolysaccharides2201422160.040 Why?
DNA Primers3201028920.040 Why?
Neoplasms, Experimental1200412760.040 Why?
Granulocyte Colony-Stimulating Factor120216480.040 Why?
Congenital Abnormalities120037070.040 Why?
Genetic Predisposition to Disease22018174460.040 Why?
Cell Line52014159970.040 Why?
Erythroid Precursor Cells120192180.040 Why?
Fetal Death120004480.040 Why?
Biological Transport, Active219703490.040 Why?
Antigens, CD34120206570.040 Why?
INDEL Mutation120192790.040 Why?
Gene Amplification1200210630.040 Why?
Globins119984150.040 Why?
Benzylamines120182230.040 Why?
Adaptor Proteins, Signal Transducing3201629160.040 Why?
Oncogenes1200312650.040 Why?
Lymphoma, Large B-Cell, Diffuse1200713780.040 Why?
Cell Division2200245680.040 Why?
Gene Expression Profiling2201194380.040 Why?
HeLa Cells2201631280.040 Why?
Reverse Transcriptase Polymerase Chain Reaction3201447510.040 Why?
Membrane Proteins1201478800.040 Why?
Radiation Tolerance220154860.040 Why?
Peripheral Blood Stem Cell Transplantation120182720.040 Why?
Syndrome1200332510.040 Why?
RNA, Small Interfering2202035050.040 Why?
Chromatids12016630.040 Why?
Polymerase Chain Reaction3201661710.040 Why?
Male1320203501180.040 Why?
Signal Transduction42014234030.040 Why?
Poly I-C120161150.040 Why?
Pilot Projects2202083240.040 Why?
HIV Infections12022167180.030 Why?
Cell Survival2201858820.030 Why?
Chromosomal Proteins, Non-Histone220157360.030 Why?
Oligodeoxyribonucleotides120177080.030 Why?
Amino Acid Sequence32019138150.030 Why?
Deamination12015260.030 Why?
Gene Knockdown Techniques1202016550.030 Why?
HIV Antibodies1202213220.030 Why?
Heparitin Sulfate120172250.030 Why?
Cell Death1202117060.030 Why?
Immunoprecipitation220099050.030 Why?
Zygote120161160.030 Why?
Oncogene Proteins v-abl12015220.030 Why?
Transplantation, Autologous1202021240.030 Why?
Hybridomas220104520.030 Why?
Fluorescent Antibody Technique2201225050.030 Why?
Mice, Inbred NOD1202018780.030 Why?
Antibodies1202324600.030 Why?
Tumor Necrosis Factors120151090.030 Why?
Antibody Formation2201514020.030 Why?
Haploinsufficiency120163280.030 Why?
Dermatitis, Contact120151290.030 Why?
Immunoglobulin gamma-Chains12014330.030 Why?
Genome2200018080.030 Why?
Thymus Gland2201312670.030 Why?
Immune Tolerance1202322580.030 Why?
Interferon-gamma1200332060.030 Why?
Hypersensitivity, Delayed120154840.030 Why?
Female1320233801940.030 Why?
Disease Models, Animal42018180290.030 Why?
Immunity, Humoral120185980.030 Why?
Cell Line, Transformed120158980.030 Why?
Infant, Newborn32023256250.030 Why?
Phenylenediamines12014900.030 Why?
Down-Regulation1202030020.030 Why?
Mice, 129 Strain120143860.030 Why?
X Chromosome119968140.030 Why?
Neoplasms42003216830.030 Why?
Codon120156110.030 Why?
Antibodies, Neutralizing1202219780.030 Why?
Receptors, Interleukin120142450.030 Why?
Integrin alpha4beta1120121210.030 Why?
Cell Proliferation32018104810.030 Why?
Transcription Factor RelA120142750.030 Why?
Streptococcus pneumoniae120187140.030 Why?
Colony-Forming Units Assay120123560.030 Why?
Histone Chaperones12012760.030 Why?
Mutagenesis, Site-Directed1201617230.030 Why?
Catalysis120147610.030 Why?
Focal Adhesion Kinase 212012860.030 Why?
Interleukin-7120121420.030 Why?
Antigens, CD1200240260.030 Why?
Autoimmunity1202013490.030 Why?
Intestine, Small2197012410.030 Why?
Oligonucleotide Array Sequence Analysis2201339200.030 Why?
Sequence Alignment2200822560.030 Why?
BRCA2 Protein120167940.030 Why?
Tissue Array Analysis120135530.020 Why?
Lupus Erythematosus, Systemic2202021040.020 Why?
Toll-Like Receptors120155920.020 Why?
Fibroblasts3201441610.020 Why?
Disease Susceptibility1201817820.020 Why?
Genetic Linkage1199624210.020 Why?
Common Variable Immunodeficiency12011930.020 Why?
Metal Metabolism, Inborn Errors11970150.020 Why?
Poly(ADP-ribose) Polymerases120124400.020 Why?
Gene Rearrangement, B-Lymphocyte, Heavy Chain12010920.020 Why?
Rodent Diseases11970570.020 Why?
Chemokine CXCL12120124640.020 Why?
Lymphopenia120122850.020 Why?
Feasibility Studies1202050780.020 Why?
Iron2197017740.020 Why?
BRCA1 Protein1201611490.020 Why?
Chemotaxis, Leukocyte120126750.020 Why?
src-Family Kinases120125510.020 Why?
Blotting, Southern120108030.020 Why?
Breast Neoplasms12016208220.020 Why?
Hematopoiesis1201820720.020 Why?
Infant32017351360.020 Why?
Active Transport, Cell Nucleus120104430.020 Why?
Adolescent42020857810.020 Why?
Peyer's Patches120091210.020 Why?
Molecular Sequence Data32008181110.020 Why?
Hydroxyurea120092900.020 Why?
Young Adult32020564300.020 Why?
Autoantigens120128920.020 Why?
Immunohistochemistry22014113660.020 Why?
HEK293 Cells1201642040.020 Why?
Enzyme Induction120074750.020 Why?
Duodenum219704830.020 Why?
Regulatory Sequences, Nucleic Acid120107940.020 Why?
Microscopy, Fluorescence1201426990.020 Why?
Methylation1200911060.020 Why?
Acetylation1200910850.020 Why?
Phenylhydrazines11966280.020 Why?
T-Lymphocyte Subsets1201518380.020 Why?
Recombinant Proteins2200966220.020 Why?
Inflammation22003106380.020 Why?
Dose-Response Relationship, Drug12018109430.020 Why?
Survival Rate32006127880.020 Why?
Nucleosomes120094940.020 Why?
Replication Protein A12005520.020 Why?
Protein Structure, Tertiary1201238460.020 Why?
Chromosomes, Mammalian120061510.020 Why?
Zebrafish1201729940.020 Why?
Protein Binding2200993860.020 Why?
Proto-Oncogene Proteins c-akt1201425030.020 Why?
Histone-Lysine N-Methyltransferase120096700.020 Why?
Cell Lineage1201425040.020 Why?
Analysis of Variance1201463650.020 Why?
Vascular Cell Adhesion Molecule-1120077070.020 Why?
Ubiquitin120098520.020 Why?
Child32020777090.010 Why?
Neurons2200093380.010 Why?
Leukemia, B-Cell12004860.010 Why?
RNA, Messenger22013130330.010 Why?
Metformin120108350.010 Why?
Sirtuin 212003970.010 Why?
Proto-Oncogene Proteins c-myc120089870.010 Why?
Doxorubicin1200922340.010 Why?
Exons1200924370.010 Why?
Cytosol120069010.010 Why?
Infertility, Male120064090.010 Why?
Infrared Rays120032490.010 Why?
Case-Control Studies12020217460.010 Why?
Erythropoiesis119667050.010 Why?
Restriction Mapping120028780.010 Why?
Sialoglycoproteins120023180.010 Why?
Binding Sites1201061140.010 Why?
Genotype22010129510.010 Why?
Homeostasis1201233400.010 Why?
Protein Processing, Post-Translational1200919900.010 Why?
Karyotyping1200312430.010 Why?
Telomere120079100.010 Why?
Biological Evolution1200710760.010 Why?
Cell Adhesion1200731440.010 Why?
Anemia1197015060.010 Why?
Polyomavirus120012480.010 Why?
Chimera120014850.010 Why?
Adult320202140550.010 Why?
Genes, Tumor Suppressor1200410970.010 Why?
Homozygote1200417850.010 Why?
Phosphoglycerate Kinase11999680.010 Why?
Neomycin11999880.010 Why?
Genes, Lethal120002420.010 Why?
Transfection1200758920.010 Why?
Chromosomes120025960.010 Why?
Receptors, Antigen, T-Cell, alpha-beta120028050.010 Why?
Proto-Oncogene Proteins1201045540.010 Why?
Gene Expression1201077990.010 Why?
Gene Expression Regulation, Neoplastic2200484280.010 Why?
Cyclin-Dependent Kinase Inhibitor p16120007050.010 Why?
Antibodies, Monoclonal1201492740.010 Why?
Growth119993760.010 Why?
Cloning, Molecular1200243200.010 Why?
Mutagenesis, Insertional119996550.010 Why?
Antigens1200114660.010 Why?
Chromosome Mapping1200447400.010 Why?
Nervous System119995540.010 Why?
Embryo, Mammalian1200017010.010 Why?
Cell Line, Tumor12010166890.010 Why?
Fetal Growth Retardation119975700.010 Why?
Life Expectancy1200011840.010 Why?
Gene Deletion1200027510.010 Why?
Chromatin1200329340.010 Why?
Iron Isotopes11970190.010 Why?
Serous Membrane11970280.010 Why?
Haploidy119701360.010 Why?
Sex Chromosomes119701050.010 Why?
Stem Cells1200235670.010 Why?
Models, Biological1200695830.010 Why?
Aged120211632800.010 Why?
Polymorphism, Single Nucleotide12007155190.000 Why?
Dactinomycin119663180.000 Why?
Arthritis, Rheumatoid1200137120.000 Why?
Leucine119665610.000 Why?
Ferritins119665900.000 Why?
DNA1197073010.000 Why?
Rats21966242600.000 Why?
Liver1196674740.000 Why?
Carbon Isotopes119664670.000 Why?
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Concepts (417)
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.