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John P. Manis, M.D.

Concepts (417)

Concepts are derived automatically from a person's publications.
Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.
Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Immunoglobulin Class Switching2620172882.610 Why?
B-Lymphocytes36202046231.190 Why?
Immunoglobulin Heavy Chains1720156491.000 Why?
Recombination, Genetic18201115420.920 Why?
Anemia, Sickle Cell5202110180.840 Why?
Cytidine Deaminase1320152500.790 Why?
DNA Repair18201519970.730 Why?
Hematopoietic Stem Cells8202133240.720 Why?
Blood Platelets2202224900.640 Why?
gamma-Globins42022890.620 Why?
Severe Combined Immunodeficiency220152180.550 Why?
DNA-Binding Proteins24201694720.520 Why?
Fetal Hemoglobin320223330.520 Why?
DNA Polymerase II120151030.500 Why?
Immunoglobulin Constant Regions42015600.480 Why?
Transplantation Conditioning1202115510.460 Why?
Platelet Transfusion120163110.430 Why?
DNA Damage12201023680.410 Why?
Nuclear Proteins15202257350.400 Why?
Genes, Immunoglobulin520032880.380 Why?
Chromosome Breakage420081650.380 Why?
YY1 Transcription Factor12011590.380 Why?
Germinal Center320203750.370 Why?
DNA Breaks, Double-Stranded620155710.350 Why?
Antigens, Nuclear520101850.350 Why?
Translocation, Genetic8200814040.350 Why?
Immunoglobulin E5201714670.340 Why?
B-Lymphocyte Subsets120112420.340 Why?
Lymphopoiesis320181320.320 Why?
DNA Breaks12008470.310 Why?
Mice, Knockout252016141470.310 Why?
Mutation162018294060.300 Why?
Nobel Prize12007480.300 Why?
Repressor Proteins4202229550.300 Why?
Mice602022795480.270 Why?
Tumor Suppressor Protein p5313200828850.270 Why?
Lymphoma3201118510.250 Why?
Genetic Techniques120074350.250 Why?
Immunoglobulin mu-Chains22011620.250 Why?
STAT3 Transcription Factor320188550.250 Why?
Hematopoietic Stem Cell Transplantation3202153760.240 Why?
Lymphoma, B-Cell920109200.240 Why?
Animals6820221654790.230 Why?
Tumor Suppressor Proteins7201227820.230 Why?
Toll-Like Receptor 9220172320.230 Why?
DNA-Activated Protein Kinase520141100.230 Why?
Hypergammaglobulinemia12003730.220 Why?
Erythroblastosis, Fetal12023620.220 Why?
Immunologic Deficiency Syndromes320175360.220 Why?
Immunoglobulin M4201014980.220 Why?
Immunoglobulin Switch Region42010460.220 Why?
Mice, Mutant Strains5201617820.210 Why?
CD8-Positive T-Lymphocytes1201644330.210 Why?
Cell Differentiation112018113130.210 Why?
Gene Rearrangement, B-Lymphocyte420081090.210 Why?
Freeze Drying12022960.200 Why?
RNA Interference1202028280.200 Why?
Hemoglobinopathies12022960.200 Why?
Intracellular Signaling Peptides and Proteins4200928440.190 Why?
Phosphoproteins3200623870.190 Why?
Guanine Nucleotide Exchange Factors220175610.190 Why?
DNA Helicases420008350.190 Why?
Somatic Hypermutation, Immunoglobulin42007980.190 Why?
Lymphocytes6201725770.190 Why?
Embryonic Stem Cells1200712570.180 Why?
Focal Adhesion Kinase 1220121180.180 Why?
Cell Cycle Proteins5201234010.180 Why?
Hematopoietic Stem Cell Mobilization220182130.170 Why?
Genes, RAG-122018680.170 Why?
Genes, Immunoglobulin Heavy Chain32008550.170 Why?
Reed-Sternberg Cells11999720.170 Why?
DNA Ligases32014790.160 Why?
Flow Cytometry10202058070.160 Why?
Protein Phosphatase 2120202270.160 Why?
Blood Component Removal120181250.150 Why?
Histones5201525510.150 Why?
Heterocyclic Compounds120182430.150 Why?
Immunoglobulin G6201444440.150 Why?
Lymphocyte Activation8202053830.150 Why?
Carrier Proteins5202249060.140 Why?
HIV Seropositivity120229510.140 Why?
Immunoglobulin Light Chains320052620.140 Why?
N-Glycosyl Hydrolases12016670.140 Why?
Genomic Instability420166850.140 Why?
Transmembrane Activator and CAML Interactor Protein12016540.140 Why?
Gene Expression Regulation42018117810.140 Why?
Neutropenia120218770.140 Why?
Bone Diseases, Developmental120171280.130 Why?
Immunoglobulin epsilon-Chains22014160.130 Why?
N-Acetylglucosaminyltransferases120171650.130 Why?
Bone Marrow2201828910.130 Why?
Homeodomain Proteins4201623790.130 Why?
Endodeoxyribonucleases120161550.130 Why?
Pneumonia, Pneumococcal120161270.130 Why?
Immunoglobulin Isotypes320021520.130 Why?
Enhancer Elements, Genetic2201913260.130 Why?
Agammaglobulinemia119961650.130 Why?
Mice, Transgenic7202094660.130 Why?
Heterozygote4201627380.130 Why?
Endonucleases520153660.120 Why?
T-Lymphocytes7202099520.120 Why?
Pneumococcal Vaccines120183850.120 Why?
I-kappa B Proteins120152120.120 Why?
Vaccines120228090.120 Why?
Erythrocytes1202324070.120 Why?
Sequence Deletion4201514970.120 Why?
Organogenesis120152060.110 Why?
Pneumococcal Infections120184950.110 Why?
Serine Endopeptidases1201810540.110 Why?
Cells, Cultured132020188420.110 Why?
Lymphoid Tissue120154460.110 Why?
Intestinal Atresia12013670.110 Why?
Poly Adenosine Diphosphate Ribose12012480.110 Why?
Adaptor Proteins, Vesicular Transport120143030.100 Why?
DNA Nucleotidyltransferases220021760.100 Why?
In Situ Hybridization, Fluorescence6200825790.100 Why?
Humans4320237354580.100 Why?
Ubiquitin-Protein Ligases2201218280.100 Why?
DNA Mutational Analysis3201541020.100 Why?
Th17 Cells120187470.100 Why?
Alleles6201867950.100 Why?
Myeloid Differentiation Factor 88220145740.100 Why?
Hodgkin Disease1199913660.100 Why?
Wiskott-Aldrich Syndrome Protein120121600.100 Why?
5' Flanking Region12010310.100 Why?
Precursor Cells, B-Lymphoid22010980.090 Why?
Fatal Outcome1201518130.090 Why?
Trans-Activators3201228530.090 Why?
Neutrophils2202136710.090 Why?
Toll-Like Receptor 4120145580.090 Why?
Deoxyribonuclease I120102220.090 Why?
Genes, Regulator220033730.090 Why?
Genetic Vectors2202033400.090 Why?
Gene Conversion22016690.090 Why?
Mice, Inbred C57BL132018213290.090 Why?
Gene Rearrangement4200311490.080 Why?
Chromosome Aberrations3200717830.080 Why?
Gene Rearrangement, T-Lymphocyte219991110.080 Why?
Developmental Disabilities1201714740.080 Why?
Chromatin Immunoprecipitation120118630.080 Why?
Chromosome Pairing12007450.080 Why?
Phosphorylation7201582670.080 Why?
beta-Thalassemia220202230.070 Why?
Suppressor of Cytokine Signaling Proteins120071720.070 Why?
Apoptosis8201894300.070 Why?
Base Sequence82019125130.070 Why?
Immunoglobulins120108620.070 Why?
Regulatory Elements, Transcriptional120071830.070 Why?
Induced Pluripotent Stem Cells2201717490.070 Why?
Gene Knockdown Techniques1202016040.070 Why?
Chromosomes, Human, Pair 15120073630.070 Why?
VDJ Recombinases22002840.070 Why?
Transplantation, Autologous1202021010.070 Why?
Models, Immunological120085080.060 Why?
Immunophenotyping3201818400.060 Why?
Immunologic Memory1201213100.060 Why?
Thymus Neoplasms220062700.060 Why?
Serine120098180.060 Why?
Mice, SCID2200226090.060 Why?
HIV-11202268350.060 Why?
Models, Genetic2200834120.060 Why?
Lysine120099770.060 Why?
Immunoblotting3201416520.060 Why?
Genes, myc220043970.060 Why?
Autoimmune Diseases1201621230.060 Why?
Cell Cycle5201429100.060 Why?
RNA, Small Interfering2202034210.060 Why?
Receptors, Antigen, B-Cell120075470.060 Why?
Child, Preschool62017408120.060 Why?
Intestines1201318810.060 Why?
Autoantibodies3202020170.060 Why?
Rho(D) Immune Globulin12023350.060 Why?
VDJ Exons22015110.060 Why?
Suppression, Genetic120041910.060 Why?
Plasma Cells220105860.060 Why?
Down-Regulation1202028850.060 Why?
Cyclic AMP-Dependent Protein Kinases120054750.060 Why?
DNA Nucleotidylexotransferase12022630.050 Why?
Transcription Factors42022119490.050 Why?
Phenotype62018160660.050 Why?
Gene Dosage1200712210.050 Why?
Pilot Projects2202082560.050 Why?
Receptors, CXCR4120077190.050 Why?
Complementarity Determining Regions120221440.050 Why?
Genes, Switch12002470.050 Why?
Interleukin-42201711130.050 Why?
Gene Knock-In Techniques220164110.050 Why?
Leukocyte Transfusion12021580.050 Why?
History, 21st Century1200715190.050 Why?
Genes, p53120047210.050 Why?
Cell Count2201818280.050 Why?
Cell Transformation, Neoplastic2200828140.050 Why?
Isoantigens120234960.050 Why?
Ubiquitination320129900.050 Why?
Enzyme-Linked Immunosorbent Assay2202037620.050 Why?
Mice, Inbred BALB C4201461550.050 Why?
Radiation, Ionizing220152480.050 Why?
beta-Lactamases120022830.050 Why?
Sirtuins120033130.050 Why?
Gene Targeting220208450.050 Why?
Transcription, Genetic3200775820.050 Why?
Neoplasm Proteins1201236270.050 Why?
Isoantibodies120236360.040 Why?
Ovarian Neoplasms1201647810.040 Why?
Granulocyte-Macrophage Colony-Stimulating Factor120038860.040 Why?
Proteins2201359750.040 Why?
Locus Control Region11999200.040 Why?
Lentivirus120224930.040 Why?
Lipopolysaccharides2201421780.040 Why?
DNA Primers3201028200.040 Why?
Neoplasms, Experimental1200412260.040 Why?
Granulocyte Colony-Stimulating Factor120216180.040 Why?
Cell Line52014156170.040 Why?
Congenital Abnormalities120036930.040 Why?
Genetic Predisposition to Disease22018172010.040 Why?
Fetal Death120004330.040 Why?
Erythroid Precursor Cells120192130.040 Why?
Biological Transport, Active219703390.040 Why?
Antigens, CD34120206450.040 Why?
Male1320203461690.040 Why?
INDEL Mutation120192760.040 Why?
Globins119984060.040 Why?
Benzylamines120182190.040 Why?
Gene Amplification1200210920.040 Why?
Oncogenes1200312170.040 Why?
Adaptor Proteins, Signal Transducing3201628620.040 Why?
Gene Expression Profiling2201192340.040 Why?
Lymphoma, Large B-Cell, Diffuse1200713710.040 Why?
Cell Division2200244470.040 Why?
Reverse Transcriptase Polymerase Chain Reaction3201445930.040 Why?
HeLa Cells2201630440.040 Why?
Radiation Tolerance220154760.040 Why?
Peripheral Blood Stem Cell Transplantation120182510.040 Why?
Membrane Proteins1201477480.040 Why?
Syndrome1200331910.040 Why?
Polymerase Chain Reaction3201660680.040 Why?
Chromatids12016640.040 Why?
Signal Transduction42014229520.040 Why?
Poly I-C120161120.030 Why?
HIV Infections12022165210.030 Why?
Cell Survival2201857580.030 Why?
Chromosomal Proteins, Non-Histone220157150.030 Why?
Amino Acid Sequence32019135380.030 Why?
Deamination12015250.030 Why?
HIV Antibodies1202212750.030 Why?
Heparitin Sulfate120172210.030 Why?
Cell Death1202116610.030 Why?
Immunoprecipitation220098770.030 Why?
Oligodeoxyribonucleotides120177700.030 Why?
Oncogene Proteins v-abl12015210.030 Why?
Fluorescent Antibody Technique2201224560.030 Why?
Hybridomas220104410.030 Why?
Mice, Inbred NOD1202018050.030 Why?
Zygote120161170.030 Why?
Female1320233767080.030 Why?
Antibodies1202324020.030 Why?
Tumor Necrosis Factors12015990.030 Why?
Antibody Formation2201513660.030 Why?
Genome2200017600.030 Why?
Immune Tolerance1202321830.030 Why?
Interferon-gamma1200331100.030 Why?
Haploinsufficiency120163240.030 Why?
Dermatitis, Contact120151290.030 Why?
Immunoglobulin gamma-Chains12014320.030 Why?
Thymus Gland2201312210.030 Why?
Hypersensitivity, Delayed120154710.030 Why?
Immunity, Humoral120185620.030 Why?
Disease Models, Animal42018177000.030 Why?
Infant, Newborn32023254030.030 Why?
Cell Line, Transformed120158780.030 Why?
Phenylenediamines12014880.030 Why?
Neoplasms42003213750.030 Why?
Mice, 129 Strain120143680.030 Why?
Antibodies, Neutralizing1202218640.030 Why?
X Chromosome119968120.030 Why?
Codon120156030.030 Why?
Adolescent42020851250.030 Why?
Cell Proliferation32018102500.030 Why?
Receptors, Interleukin120142440.030 Why?
Transcription Factor RelA120142560.030 Why?
Integrin alpha4beta1120121190.030 Why?
Streptococcus pneumoniae120187110.030 Why?
Mutagenesis, Site-Directed1201616950.030 Why?
Colony-Forming Units Assay120123490.030 Why?
Young Adult32020561510.030 Why?
Histone Chaperones12012780.030 Why?
Catalysis120147630.030 Why?
Interleukin-7120121370.030 Why?
Focal Adhesion Kinase 212012860.030 Why?
Intestine, Small2197011830.030 Why?
Antigens, CD1200238830.030 Why?
Autoimmunity1202013250.030 Why?
Oligonucleotide Array Sequence Analysis2201337880.030 Why?
Sequence Alignment2200822060.030 Why?
BRCA2 Protein120167730.020 Why?
Lupus Erythematosus, Systemic2202020660.020 Why?
Tissue Array Analysis120135450.020 Why?
Fibroblasts3201440360.020 Why?
Toll-Like Receptors120155820.020 Why?
Disease Susceptibility1201817300.020 Why?
Genetic Linkage1199623630.020 Why?
Common Variable Immunodeficiency12011920.020 Why?
Poly(ADP-ribose) Polymerases120124250.020 Why?
Metal Metabolism, Inborn Errors11970150.020 Why?
Gene Rearrangement, B-Lymphocyte, Heavy Chain12010910.020 Why?
Chemokine CXCL12120124460.020 Why?
Rodent Diseases11970500.020 Why?
Lymphopenia120122750.020 Why?
BRCA1 Protein1201611100.020 Why?
Iron2197017510.020 Why?
Chemotaxis, Leukocyte120126660.020 Why?
Feasibility Studies1202050170.020 Why?
Child32020773440.020 Why?
src-Family Kinases120125330.020 Why?
Blotting, Southern120107880.020 Why?
Breast Neoplasms12016205170.020 Why?
Hematopoiesis1201820300.020 Why?
Infant32017349480.020 Why?
Active Transport, Cell Nucleus120104200.020 Why?
Peyer's Patches120091200.020 Why?
Molecular Sequence Data32008177540.020 Why?
Hydroxyurea120092810.020 Why?
Autoantigens120128740.020 Why?
Immunohistochemistry22014112030.020 Why?
HEK293 Cells1201640980.020 Why?
Enzyme Induction120074610.020 Why?
Duodenum219704820.020 Why?
Regulatory Sequences, Nucleic Acid120107760.020 Why?
Microscopy, Fluorescence1201426620.020 Why?
Methylation1200910690.020 Why?
Acetylation1200910470.020 Why?
T-Lymphocyte Subsets1201517840.020 Why?
Recombinant Proteins2200965110.020 Why?
Phenylhydrazines11966280.020 Why?
Dose-Response Relationship, Drug12018106900.020 Why?
Inflammation22003105210.020 Why?
Survival Rate32006125130.020 Why?
Nucleosomes120094870.020 Why?
Replication Protein A12005490.020 Why?
Protein Structure, Tertiary1201237740.020 Why?
Protein Binding2200992240.020 Why?
Zebrafish1201729670.020 Why?
Chromosomes, Mammalian120061470.020 Why?
Proto-Oncogene Proteins c-akt1201424380.020 Why?
Analysis of Variance1201462130.020 Why?
Cell Lineage1201424620.020 Why?
Histone-Lysine N-Methyltransferase120096620.020 Why?
Vascular Cell Adhesion Molecule-1120076950.020 Why?
Adult320202123710.020 Why?
Ubiquitin120098280.020 Why?
Neurons2200092400.010 Why?
Leukemia, B-Cell12004830.010 Why?
RNA, Messenger22013127210.010 Why?
Sirtuin 212003920.010 Why?
Proto-Oncogene Proteins c-myc120089780.010 Why?
Metformin120108510.010 Why?
Exons1200923860.010 Why?
Doxorubicin1200921960.010 Why?
Cytosol120068830.010 Why?
Infertility, Male120063980.010 Why?
Infrared Rays120032410.010 Why?
Case-Control Studies12020214590.010 Why?
Erythropoiesis119666850.010 Why?
Binding Sites1201060090.010 Why?
Restriction Mapping120028630.010 Why?
Genotype22010126770.010 Why?
Sialoglycoproteins120023140.010 Why?
Homeostasis1201232560.010 Why?
Protein Processing, Post-Translational1200919480.010 Why?
Telomere120078940.010 Why?
Karyotyping1200312220.010 Why?
Biological Evolution1200710540.010 Why?
Anemia1197014700.010 Why?
Cell Adhesion1200730910.010 Why?
Polyomavirus120012370.010 Why?
Chimera120014510.010 Why?
Genes, Tumor Suppressor1200410610.010 Why?
Homozygote1200417350.010 Why?
Transfection1200757800.010 Why?
Genes, Lethal120002270.010 Why?
Neomycin11999890.010 Why?
Phosphoglycerate Kinase11999680.010 Why?
Chromosomes120025830.010 Why?
Receptors, Antigen, T-Cell, alpha-beta120027870.010 Why?
Proto-Oncogene Proteins1201045010.010 Why?
Gene Expression1201075780.010 Why?
Gene Expression Regulation, Neoplastic2200483010.010 Why?
Antibodies, Monoclonal1201490860.010 Why?
Cyclin-Dependent Kinase Inhibitor p16120006950.010 Why?
Growth119993660.010 Why?
Cloning, Molecular1200242150.010 Why?
Mutagenesis, Insertional119996470.010 Why?
Antigens1200114400.010 Why?
Chromosome Mapping1200446300.010 Why?
Nervous System119995410.010 Why?
Embryo, Mammalian1200016470.010 Why?
Cell Line, Tumor12010164630.010 Why?
Fetal Growth Retardation119975700.010 Why?
Life Expectancy1200011770.010 Why?
Gene Deletion1200026770.010 Why?
Chromatin1200328830.010 Why?
Iron Isotopes11970190.010 Why?
Serous Membrane11970280.010 Why?
Haploidy119701320.010 Why?
Sex Chromosomes119701030.010 Why?
Stem Cells1200234980.010 Why?
Models, Biological1200694170.010 Why?
Aged120211614950.010 Why?
Polymorphism, Single Nucleotide12007152210.000 Why?
Dactinomycin119663120.000 Why?
Arthritis, Rheumatoid1200137220.000 Why?
Leucine119665290.000 Why?
Ferritins119665740.000 Why?
DNA1197071850.000 Why?
Rats21966236440.000 Why?
Liver1196672980.000 Why?
Carbon Isotopes119664630.000 Why?
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.