Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

John P. Manis, M.D.

Concepts (425)

Back to Profile
Concepts are derived automatically from a person's publications.
Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.
Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Immunoglobulin Class Switching2620172892.520 Why?
B-Lymphocytes37202447851.230 Why?
Immunoglobulin Heavy Chains1720156480.970 Why?
Recombination, Genetic18201115260.900 Why?
Anemia, Sickle Cell6202410650.830 Why?
Hematopoietic Stem Cells9202434070.790 Why?
Cytidine Deaminase1320152430.770 Why?
DNA Repair18201520480.710 Why?
Blood Platelets2202224760.610 Why?
Severe Combined Immunodeficiency220152350.520 Why?
DNA-Binding Proteins24201696140.500 Why?
DNA Polymerase II120151040.480 Why?
Immunoglobulin Constant Regions42015580.460 Why?
Transplantation Conditioning1202116000.450 Why?
Platelet Transfusion120163010.420 Why?
gamma-Globins420221050.420 Why?
Nuclear Proteins15202258000.390 Why?
DNA Damage12201024580.390 Why?
Lymphoma, B-Cell1020249450.370 Why?
Genes, Immunoglobulin520032860.370 Why?
Chromosome Breakage420081590.370 Why?
YY1 Transcription Factor12011600.360 Why?
Germinal Center320203800.350 Why?
Fetal Hemoglobin320223460.350 Why?
Antigens, Nuclear520101830.340 Why?
Translocation, Genetic8200813950.340 Why?
DNA Breaks, Double-Stranded620156080.340 Why?
B-Lymphocyte Subsets120112410.330 Why?
Immunoglobulin E5201715060.330 Why?
Lymphopoiesis320181330.310 Why?
DNA Breaks12008470.300 Why?
Mutation172024302280.300 Why?
Hematopoietic Stem Cell Transplantation4202457130.290 Why?
Mice, Knockout252016144810.290 Why?
Nobel Prize12007460.290 Why?
Mice622024820170.280 Why?
Tumor Suppressor Protein p5313200829520.260 Why?
Genetic Techniques120074280.240 Why?
Immunoglobulin mu-Chains22011620.240 Why?
STAT3 Transcription Factor320188750.240 Why?
Lymphoma3201119070.230 Why?
Animals7020241693370.230 Why?
Toll-Like Receptor 9220171990.220 Why?
Tumor Suppressor Proteins7201228120.220 Why?
DNA-Activated Protein Kinase520141110.220 Why?
Hypergammaglobulinemia12003710.220 Why?
Erythroblastosis, Fetal12023620.220 Why?
Immunologic Deficiency Syndromes320175490.210 Why?
Mice, Mutant Strains5201617550.210 Why?
Immunoglobulin Switch Region42010440.210 Why?
Immunoglobulin M4201015280.210 Why?
Repressor Proteins4202229860.200 Why?
Gene Rearrangement, B-Lymphocyte420081110.200 Why?
CD8-Positive T-Lymphocytes1201646460.200 Why?
Freeze Drying12022970.200 Why?
Cell Differentiation112018116680.200 Why?
Hemoglobinopathies120221010.190 Why?
Intracellular Signaling Peptides and Proteins4200928900.190 Why?
Phosphoproteins3200624480.190 Why?
Guanine Nucleotide Exchange Factors220175720.190 Why?
DNA Helicases420008530.190 Why?
Somatic Hypermutation, Immunoglobulin420071030.180 Why?
Lymphocytes6201726110.180 Why?
Embryonic Stem Cells1200712490.180 Why?
Focal Adhesion Kinase 1220121200.170 Why?
Cell Cycle Proteins5201234580.170 Why?
Hematopoietic Stem Cell Mobilization220182250.170 Why?
Genes, RAG-122018680.170 Why?
Genes, Immunoglobulin Heavy Chain32008580.160 Why?
Reed-Sternberg Cells11999780.160 Why?
DNA Ligases32014810.160 Why?
Flow Cytometry10202059000.150 Why?
Protein Phosphatase 2120202310.150 Why?
Blood Component Removal120181320.140 Why?
Histones5201525920.140 Why?
Heterocyclic Compounds120182450.140 Why?
Carrier Proteins5202249360.140 Why?
HIV Seropositivity120229620.140 Why?
Immunoglobulin G6201445700.140 Why?
Lymphocyte Activation8202054960.140 Why?
Immunoglobulin Light Chains320052890.140 Why?
N-Glycosyl Hydrolases12016680.130 Why?
Gene Expression Regulation42018119180.130 Why?
Genomic Instability420167150.130 Why?
Transmembrane Activator and CAML Interactor Protein12016550.130 Why?
Neutropenia120218930.130 Why?
Bone Diseases, Developmental120171320.130 Why?
Immunoglobulin epsilon-Chains22014160.130 Why?
Bone Marrow2201829290.130 Why?
N-Acetylglucosaminyltransferases120171670.130 Why?
Homeodomain Proteins4201624290.130 Why?
Endodeoxyribonucleases120161660.120 Why?
Pneumonia, Pneumococcal120161340.120 Why?
Immunoglobulin Isotypes320021580.120 Why?
Heterozygote4201627910.120 Why?
Enhancer Elements, Genetic2201913680.120 Why?
Mice, Transgenic7202095620.120 Why?
Agammaglobulinemia119961740.120 Why?
Endonucleases520153710.120 Why?
T-Lymphocytes72020102670.120 Why?
Pneumococcal Vaccines120184140.110 Why?
I-kappa B Proteins120152100.110 Why?
Vaccines120228420.110 Why?
Erythrocytes1202324210.110 Why?
Sequence Deletion4201514970.110 Why?
Organogenesis120152140.110 Why?
Serine Endopeptidases1201810260.110 Why?
Cells, Cultured132020190220.110 Why?
Pneumococcal Infections120185290.110 Why?
Lymphoid Tissue120154460.110 Why?
Intestinal Atresia12013680.110 Why?
Poly Adenosine Diphosphate Ribose12012500.100 Why?
Adaptor Proteins, Vesicular Transport120143030.100 Why?
In Situ Hybridization, Fluorescence6200825240.100 Why?
Humans4520247683930.100 Why?
RNA Interference1202028360.100 Why?
DNA Nucleotidyltransferases220021770.100 Why?
DNA Mutational Analysis3201541200.100 Why?
Ubiquitin-Protein Ligases2201219010.100 Why?
Alleles6201868920.100 Why?
Th17 Cells120187910.090 Why?
Myeloid Differentiation Factor 88220145820.090 Why?
Hodgkin Disease1199913860.090 Why?
Wiskott-Aldrich Syndrome Protein120121630.090 Why?
5' Flanking Region12010310.090 Why?
Precursor Cells, B-Lymphoid22010990.090 Why?
Trans-Activators3201228560.090 Why?
Genetic Vectors3202434130.090 Why?
Fatal Outcome1201518370.090 Why?
Lentivirus220245190.090 Why?
Neutrophils2202137850.090 Why?
Antigens, CD34220246560.090 Why?
Toll-Like Receptor 4120145870.090 Why?
Deoxyribonuclease I120102250.090 Why?
Genes, Regulator220033730.080 Why?
Gene Conversion22016690.080 Why?
Gene Rearrangement4200311390.080 Why?
Mice, Inbred C57BL132018223550.080 Why?
Chromosome Aberrations3200717800.080 Why?
Gene Rearrangement, T-Lymphocyte219991110.080 Why?
Chromatin Immunoprecipitation120118550.070 Why?
Developmental Disabilities1201715160.070 Why?
Chromosome Pairing12007460.070 Why?
Phosphorylation7201583260.070 Why?
beta-Thalassemia220202360.070 Why?
Base Sequence82019124220.070 Why?
Apoptosis8201895160.070 Why?
Suppressor of Cytokine Signaling Proteins120071780.070 Why?
Immunoglobulins120108550.070 Why?
Regulatory Elements, Transcriptional120071820.070 Why?
Induced Pluripotent Stem Cells2201718890.070 Why?
Chromosomes, Human, Pair 15120073610.060 Why?
VDJ Recombinases22002840.060 Why?
Models, Immunological120085180.060 Why?
Immunophenotyping3201818660.060 Why?
Immunologic Memory1201213740.060 Why?
Aging1202487640.060 Why?
HIV-11202269630.060 Why?
Thymus Neoplasms220062770.060 Why?
Mice, SCID2200226320.060 Why?
Models, Genetic2200834420.060 Why?
Serine120098310.060 Why?
Lysine120099880.060 Why?
Immunoblotting3201416470.060 Why?
Genes, myc220043910.060 Why?
Cell Cycle5201429380.060 Why?
Receptors, Antigen, B-Cell120075470.060 Why?
Autoimmune Diseases1201622570.060 Why?
Intestines1201319120.060 Why?
Child, Preschool62017426500.060 Why?
Rho(D) Immune Globulin12023340.060 Why?
Suppression, Genetic120041900.060 Why?
VDJ Exons22015110.060 Why?
Autoantibodies3202021260.050 Why?
Plasma Cells220105990.050 Why?
Cyclic AMP-Dependent Protein Kinases120054840.050 Why?
DNA Nucleotidylexotransferase12022640.050 Why?
Transcription Factors42022121660.050 Why?
Proto-Oncogene Proteins c-myc220249980.050 Why?
Gene Dosage1200712210.050 Why?
Receptors, CXCR4120077290.050 Why?
Phenotype62018167210.050 Why?
Complementarity Determining Regions120221500.050 Why?
Genes, Switch12002480.050 Why?
Interleukin-42201711570.050 Why?
Transduction, Genetic120249020.050 Why?
Leukocyte Transfusion12021560.050 Why?
Gene Knock-In Techniques220164220.050 Why?
Cell Transformation, Neoplastic2200828460.050 Why?
Cell Count2201818330.050 Why?
Genes, p53120047160.050 Why?
History, 21st Century1200715750.050 Why?
Ubiquitination3201210090.050 Why?
Isoantigens120235630.050 Why?
Enzyme-Linked Immunosorbent Assay2202038130.050 Why?
Radiation, Ionizing220152520.050 Why?
Mice, Inbred BALB C4201462340.050 Why?
Clone Cells1202416710.040 Why?
beta-Lactamases120023070.040 Why?
Sirtuins120033220.040 Why?
Gene Targeting220208410.040 Why?
Neoplasm Proteins1201236100.040 Why?
Transcription, Genetic3200775990.040 Why?
Ovarian Neoplasms1201649070.040 Why?
Proteins2201360060.040 Why?
Granulocyte-Macrophage Colony-Stimulating Factor120038920.040 Why?
Isoantibodies120236820.040 Why?
Locus Control Region11999210.040 Why?
DNA Primers3201028250.040 Why?
Cell Line52014155970.040 Why?
Neoplasms, Experimental1200412320.040 Why?
Lipopolysaccharides2201422150.040 Why?
Granulocyte Colony-Stimulating Factor120216310.040 Why?
Congenital Abnormalities120037080.040 Why?
Erythroid Precursor Cells120192120.040 Why?
Fetal Death120004380.040 Why?
Genetic Predisposition to Disease22018180480.040 Why?
Biological Transport, Active219703230.040 Why?
INDEL Mutation120192670.040 Why?
Globins119984050.040 Why?
Adaptor Proteins, Signal Transducing3201629110.040 Why?
Gene Amplification1200210900.040 Why?
Oncogenes1200312350.040 Why?
Benzylamines120182510.040 Why?
Reverse Transcriptase Polymerase Chain Reaction3201445880.040 Why?
Cell Division2200244790.040 Why?
Gene Expression Profiling2201195100.040 Why?
HeLa Cells2201630880.040 Why?
Lymphoma, Large B-Cell, Diffuse1200714280.030 Why?
Radiation Tolerance220154780.030 Why?
Membrane Proteins1201478800.030 Why?
Peripheral Blood Stem Cell Transplantation120182630.030 Why?
RNA, Small Interfering2202034340.030 Why?
Syndrome1200332750.030 Why?
Polymerase Chain Reaction3201660850.030 Why?
Chromatids12016620.030 Why?
Indoles1202418250.030 Why?
Signal Transduction42014236310.030 Why?
Poly I-C120161110.030 Why?
Amino Acid Sequence32019134230.030 Why?
Cell Survival2201857920.030 Why?
Pilot Projects2202087310.030 Why?
Male1320203649020.030 Why?
Chromosomal Proteins, Non-Histone220157310.030 Why?
Gene Knockdown Techniques1202016080.030 Why?
HIV Infections12022175750.030 Why?
Oligodeoxyribonucleotides120177060.030 Why?
Deamination12015250.030 Why?
Cell Death1202116820.030 Why?
Immunoprecipitation220098740.030 Why?
Heparitin Sulfate120172240.030 Why?
HIV Antibodies1202213410.030 Why?
Oncogene Proteins v-abl12015190.030 Why?
Zygote120161150.030 Why?
Transplantation, Autologous1202021270.030 Why?
Mice, Inbred NOD1202018390.030 Why?
Hybridomas220104440.030 Why?
Fluorescent Antibody Technique2201224750.030 Why?
Antibodies1202324250.030 Why?
TOR Serine-Threonine Kinases1202420660.030 Why?
Antibody Formation2201513930.030 Why?
Tumor Necrosis Factors120151090.030 Why?
Genome2200017470.030 Why?
Interferon-gamma1200331640.030 Why?
Dermatitis, Contact120151340.030 Why?
Immunoglobulin gamma-Chains12014330.030 Why?
Haploinsufficiency120163360.030 Why?
Immune Tolerance1202323240.030 Why?
Thymus Gland2201312660.030 Why?
Immunity, Humoral120186110.030 Why?
Hypersensitivity, Delayed120154910.030 Why?
Cell Line, Transformed120158670.030 Why?
Phenylenediamines12014880.030 Why?
Female1320233970890.030 Why?
Infant, Newborn32023264110.030 Why?
Disease Models, Animal42018183620.030 Why?
Down-Regulation1202029400.030 Why?
Mice, 129 Strain120143690.030 Why?
X Chromosome119968190.030 Why?
Codon120155990.030 Why?
Neoplasms42003223850.030 Why?
Transcription Factor RelA120142540.030 Why?
Receptors, Interleukin120142430.030 Why?
Cell Proliferation32018104780.030 Why?
Antibodies, Neutralizing1202220060.030 Why?
Integrin alpha4beta1120121190.030 Why?
Mutagenesis, Site-Directed1201616820.030 Why?
Colony-Forming Units Assay120123510.030 Why?
Catalysis120147680.030 Why?
Streptococcus pneumoniae120187640.030 Why?
Histone Chaperones12012820.030 Why?
Pyrimidines1202430480.030 Why?
Interleukin-7120121450.030 Why?
Focal Adhesion Kinase 212012870.020 Why?
Oligonucleotide Array Sequence Analysis2201337940.020 Why?
Intestine, Small2197012180.020 Why?
Antigens, CD1200240310.020 Why?
Sequence Alignment2200821760.020 Why?
Autoimmunity1202013600.020 Why?
BRCA2 Protein120168020.020 Why?
Tissue Array Analysis120135510.020 Why?
Toll-Like Receptors120155820.020 Why?
Disease Susceptibility1201817940.020 Why?
Genetic Linkage1199623420.020 Why?
Lupus Erythematosus, Systemic2202021700.020 Why?
Fibroblasts3201441770.020 Why?
Epigenesis, Genetic1202438270.020 Why?
Poly(ADP-ribose) Polymerases120124270.020 Why?
Metal Metabolism, Inborn Errors11970140.020 Why?
Common Variable Immunodeficiency120111000.020 Why?
Gene Rearrangement, B-Lymphocyte, Heavy Chain12010910.020 Why?
Chemokine CXCL12120124570.020 Why?
Rodent Diseases11970530.020 Why?
Lymphopenia120122990.020 Why?
DNA Methylation1202444210.020 Why?
BRCA1 Protein1201611550.020 Why?
Chemotaxis, Leukocyte120126600.020 Why?
Iron2197018140.020 Why?
src-Family Kinases120125390.020 Why?
Blotting, Southern120107770.020 Why?
Hematopoiesis1201820580.020 Why?
Breast Neoplasms12016211620.020 Why?
Active Transport, Cell Nucleus120104320.020 Why?
Molecular Sequence Data32008176260.020 Why?
Feasibility Studies1202053130.020 Why?
Infant32017365100.020 Why?
Peyer's Patches120091200.020 Why?
Adolescent42020891840.020 Why?
Hydroxyurea120092840.020 Why?
Autoantigens120128910.020 Why?
Immunohistochemistry22014111200.020 Why?
Young Adult32020600490.020 Why?
Enzyme Induction120074550.020 Why?
HEK293 Cells1201642910.020 Why?
Duodenum219704950.020 Why?
Microscopy, Fluorescence1201426360.020 Why?
Regulatory Sequences, Nucleic Acid120107920.020 Why?
Acetylation1200910530.020 Why?
Methylation1200910760.020 Why?
T-Lymphocyte Subsets1201518130.020 Why?
Recombinant Proteins2200965100.020 Why?
Phenylhydrazines11966280.020 Why?
Dose-Response Relationship, Drug12018107760.020 Why?
Inflammation22003108630.020 Why?
Survival Rate32006128700.020 Why?
Nucleosomes120094890.020 Why?
Protein Structure, Tertiary1201237790.020 Why?
Replication Protein A12005540.020 Why?
Analysis of Variance1201462410.020 Why?
Chromosomes, Mammalian120061480.020 Why?
Protein Binding2200993430.020 Why?
Proto-Oncogene Proteins c-akt1201424600.020 Why?
Zebrafish1201730370.020 Why?
Cell Lineage1201425740.020 Why?
Vascular Cell Adhesion Molecule-1120076920.020 Why?
Histone-Lysine N-Methyltransferase120096970.020 Why?
Ubiquitin120098420.010 Why?
Neurons2200095130.010 Why?
Child32020808910.010 Why?
Leukemia, B-Cell12004860.010 Why?
RNA, Messenger22013128050.010 Why?
Sirtuin 212003930.010 Why?
Exons1200923920.010 Why?
Doxorubicin1200922290.010 Why?
Cytosol120068860.010 Why?
Metformin120109110.010 Why?
Infertility, Male120063970.010 Why?
Infrared Rays120032490.010 Why?
Erythropoiesis119666930.010 Why?
Case-Control Studies12020222960.010 Why?
Binding Sites1201060170.010 Why?
Restriction Mapping120028490.010 Why?
Sialoglycoproteins120023200.010 Why?
Genotype22010130420.010 Why?
Protein Processing, Post-Translational1200919670.010 Why?
Homeostasis1201233490.010 Why?
Karyotyping1200311730.010 Why?
Telomere120079430.010 Why?
Cell Adhesion1200731020.010 Why?
Biological Evolution1200710780.010 Why?
Anemia1197015190.010 Why?
Polyomavirus120012350.010 Why?
Chimera120014540.010 Why?
Genes, Tumor Suppressor1200410640.010 Why?
Transfection1200757640.010 Why?
Adult320202236400.010 Why?
Genes, Lethal120002230.010 Why?
Homozygote1200417790.010 Why?
Phosphoglycerate Kinase11999660.010 Why?
Neomycin11999940.010 Why?
Chromosomes120025790.010 Why?
Receptors, Antigen, T-Cell, alpha-beta120028080.010 Why?
Proto-Oncogene Proteins1201045260.010 Why?
Gene Expression1201075980.010 Why?
Gene Expression Regulation, Neoplastic2200486340.010 Why?
Antibodies, Monoclonal1201492610.010 Why?
Cyclin-Dependent Kinase Inhibitor p16120007100.010 Why?
Growth119993660.010 Why?
Cloning, Molecular1200241680.010 Why?
Mutagenesis, Insertional119996620.010 Why?
Antigens1200114430.010 Why?
Chromosome Mapping1200446220.010 Why?
Nervous System119995470.010 Why?
Embryo, Mammalian1200016740.010 Why?
Cell Line, Tumor12010171350.010 Why?
Fetal Growth Retardation119975910.010 Why?
Life Expectancy1200012490.010 Why?
Gene Deletion1200026730.010 Why?
Chromatin1200329680.010 Why?
Iron Isotopes11970190.010 Why?
Serous Membrane11970230.010 Why?
Haploidy119701270.010 Why?
Sex Chromosomes119701010.010 Why?
Stem Cells1200235390.010 Why?
Models, Biological1200694930.010 Why?
Aged120211715620.000 Why?
Polymorphism, Single Nucleotide12007160280.000 Why?
Dactinomycin119663050.000 Why?
Arthritis, Rheumatoid1200137770.000 Why?
Leucine119665480.000 Why?
Ferritins119666000.000 Why?
DNA1197072110.000 Why?
Rats21966238350.000 Why?
Liver1196675740.000 Why?
Carbon Isotopes119664580.000 Why?
Manis's Networks
Click the
Explore
buttons for more information and interactive visualizations!
Concepts (425)
Explore
_
Co-Authors (92)
Explore
_
Similar People (60)
Explore
_
Same Department 
Explore
_
Physical Neighbors
_
© 2025 President and Fellows of Harvard College
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.