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Thea Brennan-Krohn, M.D.

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Available: 11/30/22, Expires: 12/01/24

My lab performs research investigating novel treatment approaches for multidrug-resistant gram-negative bacteria including E. coli, Klebsiella, Burkholderia, Pseudomonas, and Acinetobacter. We are particularly focused on the identification of combinations of existing antibiotic and non-antibiotic drugs that prevent the emergence of resistance during treatment and on understanding how resistance to these drugs and drug combinations develops using genomic and transcriptomic approaches. A variety of projects in these areas are available for medical students, including antimicrobial susceptibility testing, time-kill assays, and sequencing and analysis of genomic data. Projects can be adapted to the student's areas of interest.


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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.