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George Andrew Alba, M.D.

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Biography
2011
Alpha Omega Alpha
2011
Barry Coller Award for Excellence in Clinical Medicine

Overview

Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. 5KL2TR002542-02 (George Alba) Oct 1, 2019 - Sep 30, 2021
    NIH / Harvard Catalyst
    NEDD9 Regulates Platelet-Endothelial Adhesion and Pulmonary Arterial Thrombosis
    Role Description: The focus of this career development award is to develop and validate a custom antibody that targets the binding region between pulmonary artery endothelial cell NEDD9 and platelet P-Selectin.
  2. F32HL139019 (ALBA, GEORGE A) Aug 2, 2017 - Aug 1, 2019
    NIH
    NEDD9 promotes thrombosis and vascular remodeling in chronic thromboembolic pulmonary hypertension
    Role: Principal Investigator

Featured Content

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Okin D, Huang CY, Alba GA, Jesudasen SJ, Dandawate NA, Gavralidis A, Chang LL, Moin EE, Ahmad I, Witkin AS, Hardin CC, Hibbert KA, Kadar A, Gordan PL, Lee H, Thompson BT, Bebell LM, Lai PS. Prolonged Prone Position Ventilation Is Associated With Reduced Mortality in Intubated COVID-19 Patients. Chest. 2022 Nov 04. PMID: 36343687; PMCID: PMC9635255.
    Citations:    Fields:    
  2. Villalba JA, Hilburn CF, Garlin MA, Elliott GA, Li Y, Kunitoki K, Poli S, Alba GA, Madrigal E, Taso M, Price MC, Aviles AJ, Araujo-Medina M, Bonanno L, Boyraz B, Champion SN, Harris CK, Helland TL, Hutchison B, Jobbagy S, Marshall MS, Shepherd DJ, Barth JL, Hung YP, Ly A, Hariri LP, Turbett SE, Pierce VM, Branda JA, Rosenberg ES, Mendez-Pena J, Chebib I, Rosales IA, Smith RN, Miller MA, Rosas IO, Hardin CC, Baden LR, Medoff BD, Colvin RB, Little BP, Stone JR, Mino-Kenudson M, Shih AR. Vasculopathy and Increased Vascular Congestion in Fatal COVID-19 and Acute Respiratory Distress Syndrome. Am J Respir Crit Care Med. 2022 10 01; 206(7):857-873. PMID: 35671465; PMCID: PMC9799276.
    Citations:    Fields:    
  3. Alba GA. Double Jeopardy: Precapillary Pulmonary Hypertension Increases the Risk of Hospitalization and Death from COVID-19. Am J Respir Crit Care Med. 2022 09 01; 206(5):526-528. PMID: 35584345; PMCID: PMC9716902.
    Citations:    Fields:    
  4. Knipe RS, Alba GA, Harvey Barnes JM, Hariri LP. Case 15-2022: A 57-Year-Old Man with Persistent Cough and Pulmonary Opacities. N Engl J Med. 2022 05 19; 386(20):1933-1944. PMID: 35584159.
    Citations:    Fields:    Translation:Humans
  5. Alba GA, Samokhin AO, Wang RS, Wertheim BM, Haley KJ, Padera RF, Vargas SO, Rosas IO, Hariri LP, Shih A, Thompson BT, Mitchell RN, Maron BA. Pulmonary endothelial NEDD9 and the prothrombotic pathophenotype of acute respiratory distress syndrome due to SARS-CoV-2 infection. Pulm Circ. 2022 Apr; 12(2):e12071. PMID: 35599981; PMCID: PMC9111030.
    Citations: 2     
  6. Moin EE, Okin D, Jesudasen SJ, Dandawate NA, Gavralidis A, Chang LL, Witkin AS, Hibbert KA, Kadar A, Gordan PL, Bebell LM, Lai PS, Alba GA. Code status orders in patients admitted to the intensive care unit with COVID-19: A retrospective cohort study. Resusc Plus. 2022 Jun; 10:100219. PMID: 35284847; PMCID: PMC8898738.
    Citations:    
  7. Maley JH, Alba GA, Barry JT, Bartels MN, Fleming TK, Oleson CV, Rydberg L, Sampsel S, Silver JK, Sipes S, Verduzco-Gutierrez M, Wood J, Zibrak JD, Whiteson J. Multi-disciplinary collaborative consensus guidance statement on the assessment and treatment of breathing discomfort and respiratory sequelae in patients with post-acute sequelae of SARS-CoV-2 infection (PASC). PM R. 2022 01; 14(1):77-95. PMID: 34902224.
    Citations: 3     Fields:    Translation:HumansCells
  8. Melms JC, Biermann J, Huang H, Wang Y, Nair A, Tagore S, Katsyv I, Rendeiro AF, Amin AD, Schapiro D, Frangieh CJ, Luoma AM, Filliol A, Fang Y, Ravichandran H, Clausi MG, Alba GA, Rogava M, Chen SW, Ho P, Montoro DT, Kornberg AE, Han AS, Bakhoum MF, Anandasabapathy N, Suárez-Fariñas M, Bakhoum SF, Bram Y, Borczuk A, Guo XV, Lefkowitch JH, Marboe C, Lagana SM, Del Portillo A, Tsai EJ, Zorn E, Markowitz GS, Schwabe RF, Schwartz RE, Elemento O, Saqi A, Hibshoosh H, Que J, Izar B. Author Correction: A molecular single-cell lung atlas of lethal COVID-19. Nature. 2021 Oct; 598(7882):E2. PMID: 34625743; PMCID: PMC8498978.
    Citations:    Fields:    
  9. Yen Li M, Alba GA, Mitton J, Bearnot B. Care-engaged individuals with polysubstance use in Northeastern US are undertreated for methamphetamine use disorder: a retrospective cohort study. Addict Sci Clin Pract. 2021 09 26; 16(1):57. PMID: 34565489; PMCID: PMC8474730.
    Citations:    Fields:    Translation:Humans
  10. Alba GA, Ziehr DR, Rouvina JN, Hariri LP, Knipe RS, Medoff BD, Hibbert KA, Kowal A, Hoenstine C, Ginns LC, Lewis GD, Hardin CC. Exercise performance in patients with post-acute sequelae of SARS-CoV-2 infection compared to patients with unexplained dyspnea. EClinicalMedicine. 2021 Sep; 39:101066. PMID: 34476393; PMCID: PMC8401400.
    Citations: 4     
  11. Alba GA, Atri D, Darbha S, Singh I, Tapson VF, Lewis MI, Chun HJ, Yu YR, Maron BA, Rajagopal S. Chronic Thromboembolic Pulmonary Hypertension: the Bench. Curr Cardiol Rep. 2021 08 19; 23(10):141. PMID: 34410515.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  12. Alba GA, Samokhin AO, Wang RS, Zhang YY, Wertheim BM, Arons E, Greenfield EA, Lundberg Slingsby MH, Ceglowski JR, Haley KJ, Bowman FP, Yu YR, Haney JC, Eng G, Mitchell RN, Sheets A, Vargas SO, Seo S, Channick RN, Leary PJ, Rajagopal S, Loscalzo J, Battinelli EM, Maron BA. NEDD9 Is a Novel and Modifiable Mediator of Platelet-Endothelial Adhesion in the Pulmonary Circulation. Am J Respir Crit Care Med. 2021 06 15; 203(12):1533-1545. PMID: 33523764; PMCID: PMC8483217.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  13. Egbuonu K, Hyle EP, Hurtado RM, Alba GA, Zachary KC, Branda JA, Hibbert KA, Hooper DC, Shenoy ES, Turbett SE, Dugdale CM. Yield of Severe Acute Respiratory Syndrome Coronavirus 2 Lower Respiratory Tract Testing After a Negative Nasopharyngeal Test Among Hospitalized Persons Under Investigation for Coronavirus Disease 2019. Open Forum Infect Dis. 2021 Jun; 8(6):ofab257. PMID: 34113690.
    Citations: 1     
  14. Melms JC, Biermann J, Huang H, Wang Y, Nair A, Tagore S, Katsyv I, Rendeiro AF, Amin AD, Schapiro D, Frangieh CJ, Luoma AM, Filliol A, Fang Y, Ravichandran H, Clausi MG, Alba GA, Rogava M, Chen SW, Ho P, Montoro DT, Kornberg AE, Han AS, Bakhoum MF, Anandasabapathy N, Suárez-Fariñas M, Bakhoum SF, Bram Y, Borczuk A, Guo XV, Lefkowitch JH, Marboe C, Lagana SM, Del Portillo A, Tsai EJ, Zorn E, Markowitz GS, Schwabe RF, Schwartz RE, Elemento O, Saqi A, Hibshoosh H, Que J, Izar B. A molecular single-cell lung atlas of lethal COVID-19. Nature. 2021 07; 595(7865):114-119. PMID: 33915568; PMCID: PMC8814825.
    Citations: 62     Fields:    Translation:HumansCells
  15. Bai C, Chotirmall SH, Rello J, Alba GA, Ginns LC, Krishnan JA, Rogers R, Bendstrup E, Burgel PR, Chalmers JD, Chua A, Crothers KA, Duggal A, Kim YW, Laffey JG, Luna CM, Niederman MS, Raghu G, Ramirez JA, Riera J, Roca O, Tamae-Kakazu M, Torres A, Watkins RR, Barrecheguren M, Belliato M, Chami HA, Chen R, Cortes-Puentes GA, Delacruz C, Hayes MM, Heunks LMA, Holets SR, Hough CL, Jagpal S, Jeon K, Johkoh T, Lee MM, Liebler J, McElvaney GN, Moskowitz A, Oeckler RA, Ojanguren I, O'Regan A, Pletz MW, Rhee CK, Schultz MJ, Storti E, Strange C, Thomson CC, Torriani FJ, Wang X, Wuyts W, Xu T, Yang D, Zhang Z, Wilson KC. Updated guidance on the management of COVID-19: from an American Thoracic Society/European Respiratory Society coordinated International Task Force (29 July 2020). Eur Respir Rev. 2020 Sep 30; 29(157). PMID: 33020069; PMCID: PMC7537943.
    Citations: 41     Fields:    Translation:HumansCellsPHPublic Health
  16. Albutt K, Luckhurst CM, Alba GA, Hechi ME, Mokhtari A, Breen K, Wing J, Akeju O, Kalva SP, Mullen JT, Lillemoe KD, Kaafarani H. Design and Impact of a COVID-19 Multidisciplinary Bundled Procedure Team. Ann Surg. 2020 08; 272(2):e72-e73. PMID: 32675501; PMCID: PMC7268858.
    Citations: 3     Fields:    Translation:HumansCellsPHPublic Health
  17. Johnson SF, Tiako MJN, Flash MJE, Lamas DJ, Alba GA. Disparities in the recovery from critical illness due to COVID-19. Lancet Psychiatry. 2020 08; 7(8):e54-e55. PMID: 32711716.
    Citations: 4     Fields:    Translation:HumansPHPublic Health
  18. Maron BA, Brittain EL, Hess E, Waldo SW, Barón AE, Huang S, Goldstein RH, Assad T, Wertheim BM, Alba GA, Leopold JA, Olschewski H, Galiè N, Simonneau G, Kovacs G, Tedford RJ, Humbert M, Choudhary G. Pulmonary vascular resistance and clinical outcomes in patients with pulmonary hypertension: a retrospective cohort study. Lancet Respir Med. 2020 09; 8(9):873-884. PMID: 32730752; PMCID: PMC8219057.
    Citations: 25     Fields:    Translation:Humans
  19. Albutt K, Luckhurst CM, Alba GA, Hechi ME, Mokhtari A, Breen K, Wing J, Akeju O, Kalva SP, Mullen JT, Lillemoe KD, Kaafarani H. Design and Impact of a COVID-19 Multidisciplinary Bundled Procedure Team. Ann Surg. 2020 May 20. PMID: 32433298.
    Citations:    
  20. Samokhin AO, Hsu S, Yu PB, Waxman AB, Alba GA, Wertheim BM, Hopkins CD, Bowman F, Channick RN, Nikolic I, Faria-Urbina M, Hassoun PM, Leopold JA, Tedford RJ, Ventetuolo CE, Leary PJ, Maron BA. Circulating NEDD9 is increased in pulmonary arterial hypertension: A multicenter, retrospective analysis. J Heart Lung Transplant. 2020 04; 39(4):289-299. PMID: 31952977.
    Citations: 8     Fields:    Translation:HumansCells
  21. Wertheim BM, Lin YD, Zhang YY, Samokhin AO, Alba GA, Arons E, Yu PB, Maron BA. Isolating pulmonary microvascular endothelial cells ex vivo: Implications for pulmonary arterial hypertension, and a caution on the use of commercial biomaterials. PLoS One. 2019; 14(2):e0211909. PMID: 30811450; PMCID: PMC6392245.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  22. Alba GA, Dudzinski DM. Case 31-2018: A Man with a Self-Inflicted Gunshot Wound. N Engl J Med. 2019 01 24; 380(4):400-1. PMID: 30673549.
    Citations:    Fields:    Translation:Humans
  23. Sacks CA, Kamalian S, Masiakos PT, Alba GA, Patalas ED. Case 31-2018: A 37-Year-Old Man with a Self-Inflicted Gunshot Wound. N Engl J Med. 2018 Oct 11; 379(15):1464-1472. PMID: 30304661.
    Citations:    Fields:    Translation:Humans
  24. Samokhin AO, Stephens T, Wertheim BM, Wang RS, Vargas SO, Yung LM, Cao M, Brown M, Arons E, Dieffenbach PB, Fewell JG, Matar M, Bowman FP, Haley KJ, Alba GA, Marino SM, Kumar R, Rosas IO, Waxman AB, Oldham WM, Khanna D, Graham BB, Seo S, Gladyshev VN, Yu PB, Fredenburgh LE, Loscalzo J, Leopold JA, Maron BA. NEDD9 targets COL3A1 to promote endothelial fibrosis and pulmonary arterial hypertension. Sci Transl Med. 2018 06 13; 10(445). PMID: 29899023.
    Citations: 47     Fields:    Translation:HumansAnimalsCells
  25. Oldham WM, Oliveira RKF, Wang RS, Opotowsky AR, Rubins DM, Hainer J, Wertheim BM, Alba GA, Choudhary G, Tornyos A, MacRae CA, Loscalzo J, Leopold JA, Waxman AB, Olschewski H, Kovacs G, Systrom DM, Maron BA. Network Analysis to Risk Stratify Patients With Exercise Intolerance. Circ Res. 2018 03 16; 122(6):864-876. PMID: 29437835; PMCID: PMC5924425.
    Citations: 22     Fields:    Translation:Humans
  26. Sacks CA, Alba GA, Miloslavsky EM. The Evolution of Procedural Competency in Internal Medicine Training. JAMA Intern Med. 2017 12 01; 177(12):1713-1714. PMID: 29059281.
    Citations: 4     Fields:    Translation:Humans
  27. Nakamura K, Alba GA, Scheske JA, Meyersohn NM, Stone JR, Vlahakes GJ, Wright CD, Ghoshhajra BB, Dudzinski DM. A 57-Year-Old Man With Insidious Dyspnea and Nonpleuritic Chest and Back Pain. Chest. 2016 Aug; 150(2):e41-7. PMID: 27502992.
    Citations: 1     Fields:    Translation:Humans
  28. Miloslavsky EM, Sargsyan Z, Heath JK, Kohn R, Alba GA, Gordon JA, Currier PF. A simulation-based resident-as-teacher program: The impact on teachers and learners. J Hosp Med. 2015 Dec; 10(12):767-72. PMID: 26173641.
    Citations: 4     Fields:    Translation:Humans
  29. Alba GA, Truong QA, Gaggin HK, Gandhi PU, De Berardinis B, Magrini L, Bajwa EK, Di Somma S, Januzzi JL. Diagnostic and Prognostic Utility of Procalcitonin in Patients Presenting to the Emergency Department with Dyspnea. Am J Med. 2016 Jan; 129(1):96-104.e7. PMID: 26169892.
    Citations: 19     Fields:    Translation:Humans
  30. Alba GA, Kelmenson DA. Optimising debriefing for technology-enhanced simulation. Med Educ. 2014 Jul; 48(7):648-50. PMID: 24909523.
    Citations:    Fields:    Translation:Humans
  31. Alba GA, Kelmenson DA, Noble VE, Murray AF, Currier PF. Faculty staff-guided versus self-guided ultrasound training for internal medicine residents. Med Educ. 2013 Nov; 47(11):1099-108. PMID: 24117556.
    Citations: 10     Fields:    Translation:Humans
  32. Parikh RB, Alba GA, Zukerberg LR. Tense ascites in a postpartum woman. Gastroenterology. 2013 Feb; 144(2):272-467. PMID: 23253295.
    Citations:    Fields:    Translation:Humans
  33. Ng A, Wong M, Viviano B, Erlich JM, Alba G, Pflederer C, Jay PY, Saunders S. Loss of glypican-3 function causes growth factor-dependent defects in cardiac and coronary vascular development. Dev Biol. 2009 Nov 01; 335(1):208-15. PMID: 19733558.
    Citations: 19     Fields:    Translation:HumansAnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.