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Last Name

Andrew Roger Osborne, PH.D.

TitleResearch Fellow in Cell Biology (INT)
InstitutionHarvard Medical School
DepartmentCell Biology
AddressHarvard Medical School
Cell Biology/Rapoport
240 Longwood Ave
Boston MA 02115
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 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Tarr SJ, Moon RW, Hardege I, Osborne AR. A conserved domain targets exported PHISTb family proteins to the periphery of Plasmodium infected erythrocytes. Mol Biochem Parasitol. 2014 Aug; 196(1):29-40.
    View in: PubMed
  2. Tarr SJ, Cryar A, Thalassinos K, Haldar K, Osborne AR. The C-terminal portion of the cleaved HT motif is necessary and sufficient to mediate export of proteins from the malaria parasite into its host cell. Mol Microbiol. 2013 Feb; 87(4):835-50.
    View in: PubMed
  3. Osborne AR, Speicher KD, Tamez PA, Bhattacharjee S, Speicher DW, Haldar K. The host targeting motif in exported Plasmodium proteins is cleaved in the parasite endoplasmic reticulum. Mol Biochem Parasitol. 2010 May; 171(1):25-31.
    View in: PubMed
  4. Erlandson KJ, Miller SB, Nam Y, Osborne AR, Zimmer J, Rapoport TA. A role for the two-helix finger of the SecA ATPase in protein translocation. Nature. 2008 Oct 16; 455(7215):984-7.
    View in: PubMed
  5. Erlandson KJ, Or E, Osborne AR, Rapoport TA. Analysis of polypeptide movement in the SecY channel during SecA-mediated protein translocation. J Biol Chem. 2008 Jun 6; 283(23):15709-15.
    View in: PubMed
  6. Ménétret JF, Schaletzky J, Clemons WM, Osborne AR, Skånland SS, Denison C, Gygi SP, Kirkpatrick DS, Park E, Ludtke SJ, Rapoport TA, Akey CW. Ribosome binding of a single copy of the SecY complex: implications for protein translocation. Mol Cell. 2007 Dec 28; 28(6):1083-92.
    View in: PubMed
  7. Osborne AR, Rapoport TA. Protein translocation is mediated by oligomers of the SecY complex with one SecY copy forming the channel. Cell. 2007 Apr 6; 129(1):97-110.
    View in: PubMed
  8. Osborne A, Flett A, Smythe E. Endocytosis assays in intact and permeabilized cells. Curr Protoc Cell Biol. 2005 Jul; Chapter 11:Unit 11.18.
    View in: PubMed
  9. Osborne AR, Rapoport TA, van den Berg B. Protein translocation by the Sec61/SecY channel. Annu Rev Cell Dev Biol. 2005; 21:529-50.
    View in: PubMed
  10. Ye J, Osborne AR, Groll M, Rapoport TA. RecA-like motor ATPases--lessons from structures. Biochim Biophys Acta. 2004 Nov 4; 1659(1):1-18.
    View in: PubMed
  11. Osborne AR, Clemons WM, Rapoport TA. A large conformational change of the translocation ATPase SecA. Proc Natl Acad Sci U S A. 2004 Jul 27; 101(30):10937-42.
    View in: PubMed
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