Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Rachel Laura Wolfson, M.D., Ph.D.

Concepts

This page shows the publications Rachel Wolfson has written about TOR Serine-Threonine Kinases.
Connection Strength

1.191
  1. KICSTOR recruits GATOR1 to the lysosome and is necessary for nutrients to regulate mTORC1. Nature. 2017 03 16; 543(7645):438-442.
    View in: PubMed
    Score: 0.339
  2. Sestrin2 is a leucine sensor for the mTORC1 pathway. Science. 2016 Jan 01; 351(6268):43-8.
    View in: PubMed
    Score: 0.309
  3. A mouse model of DEPDC5-related epilepsy: Neuronal loss of Depdc5 causes dysplastic and ectopic neurons, increased mTOR signaling, and seizure susceptibility. Neurobiol Dis. 2018 03; 111:91-101.
    View in: PubMed
    Score: 0.090
  4. mTORC1 Activator SLC38A9 Is Required to Efflux Essential Amino Acids from Lysosomes and Use Protein as a Nutrient. Cell. 2017 Oct 19; 171(3):642-654.e12.
    View in: PubMed
    Score: 0.089
  5. Recurrent mTORC1-activating RRAGC mutations in follicular lymphoma. Nat Genet. 2016 Feb; 48(2):183-8.
    View in: PubMed
    Score: 0.078
  6. Structural basis for leucine sensing by the Sestrin2-mTORC1 pathway. Science. 2016 Jan 01; 351(6268):53-8.
    View in: PubMed
    Score: 0.078
  7. Metabolism. Lysosomal amino acid transporter SLC38A9 signals arginine sufficiency to mTORC1. Science. 2015 Jan 09; 347(6218):188-94.
    View in: PubMed
    Score: 0.073
  8. The Sestrins interact with GATOR2 to negatively regulate the amino-acid-sensing pathway upstream of mTORC1. Cell Rep. 2014 Oct 09; 9(1):1-8.
    View in: PubMed
    Score: 0.072
  9. Regulation of mTORC1 by the Rag GTPases is necessary for neonatal autophagy and survival. Nature. 2013 Jan 31; 493(7434):679-83.
    View in: PubMed
    Score: 0.064
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.

Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.