Harvard Catalyst Profiles

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Amy Tsurumi, Ph.D.


The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R03AI151499 (TSURUMI, AMY) Jan 1, 2021 - Dec 31, 2022
    Multi Biomarker-based prediction tool development to determine risk of infections-related outcomes among severe blunt trauma patients
    Role: Principal Investigator

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Tsurumi A, Flaherty PJ, Que YA, Ryan CM, Banerjee A, Chakraborty A, Almpani M, Shankar M, Goverman J, Schulz JT, Sheridan RL, Friedstat J, Hickey SA, Tompkins RG, Rahme LG. A PREVENTIVE TOOL FOR PREDICTING BLOODSTREAM INFECTIONS IN CHILDREN WITH BURNS. Shock. 2023 Mar 01; 59(3):393-399. PMID: 36597771.
    Citations:    Fields:    
  2. Tsurumi A, Flaherty PJ, Que YA, Ryan CM, Mendoza AE, Almpani M, Bandyopadhaya A, Ogura A, Dhole YV, Goodfield LF, Tompkins RG, Rahme LG. Multi-Biomarker Prediction Models for Multiple Infection Episodes Following Blunt Trauma. iScience. 2020 Nov 20; 23(11):101659. PMID: 33047099.
  3. Tsurumi A, Li WX. Aging mechanisms-A perspective mostly from Drosophila. Adv Genet (Hoboken). 2020 Dec; 1(1):e10026. PMID: 36619249; PMCID: PMC9744567.
    Citations: 1     
  4. Oral E, Wannomae KW, Gil D, Connolly R, Gardecki JA, Leung HM, Muratoglu OK, Tsurumi A, Rahme L, Jaber T, Collins C, Gjore J, Budzilowicz A. Efficacy of moist heat decontamination against various pathogens for the reuse of N95 respirators in the COVID-19 emergency. MedRxiv (preprint). 2020.
  5. Almpani M, Tsurumi A, Peponis T, Dhole YV, Goodfield LF, Tompkins RG, Rahme LG. Denver and Marshall scores successfully predict susceptibility to multiple independent infections in trauma patients. PLoS One. 2020; 15(4):e0232175. PMID: 32348343.
    Citations: 2     Fields:    Translation:Humans
  6. Kühn F, Adiliaghdam F, Cavallaro PM, Hamarneh SR, Tsurumi A, Hoda RS, Munoz AR, Dhole Y, Ramirez JM, Liu E, Vasan R, Liu Y, Samarbafzadeh E, Nunez RA, Farber MZ, Chopra V, Malo MS, Rahme LG, Hodin RA. Intestinal alkaline phosphatase targets the gut barrier to prevent aging. JCI Insight. 2020 03 26; 5(6). PMID: 32213701.
    Citations: 22     Fields:    Translation:Animals
  7. Ogura A, Tsurumi A, Que YA, Almpani M, Zheng H, Tompkins RG, Ryan CM, Rahme LG. Associations between clinical characteristics and the development of multiple organ failure after severe burns in adult patients. Burns. 2019 12; 45(8):1775-1782. PMID: 31690472.
    Citations:    Fields:    Translation:Humans
  8. Tsurumi A, Xue S, Zhang L, Li J, Li WX. Genome-wide Kdm4 histone demethylase transcriptional regulation in Drosophila. Mol Genet Genomics. 2019 Oct; 294(5):1107-1121. PMID: 31020413; PMCID: PMC6813854.
    Citations: 3     Fields:    Translation:AnimalsCells
  9. Tsurumi A, Zhao C, Li WX. Canonical and non-canonical JAK/STAT transcriptional targets may be involved in distinct and overlapping cellular processes. BMC Genomics. 2017 Sep 11; 18(1):718. PMID: 28893190.
    Citations: 6     Fields:    Translation:Cells
  10. Bandyopadhaya A, Tsurumi A, Rahme LG. NF-?Bp50 and HDAC1 Interaction Is Implicated in the Host Tolerance to Infection Mediated by the Bacterial Quorum Sensing Signal 2-Aminoacetophenone. Front Microbiol. 2017; 8:1211. PMID: 28713342; PMCID: PMC5492500.
    Citations: 4     
  11. Tsurumi A, Que YA, Ryan CM, Tompkins RG, Rahme LG. TNF-a/IL-10 Ratio Correlates with Burn Severity and May Serve as a Risk Predictor of Increased Susceptibility to Infections. Front Public Health. 2016; 4:216. PMID: 27761434; PMCID: PMC5050217.
    Citations: 16     Fields:    
  12. Bandyopadhaya A, Tsurumi A, Maura D, Jeffrey KL, Rahme LG. A quorum-sensing signal promotes host tolerance training through HDAC1-mediated epigenetic reprogramming. Nat Microbiol. 2016 Oct 03; 1:16174. PMID: 27694949.
    Citations: 18     Fields:    Translation:HumansAnimalsCells
  13. Tsurumi A, Que YA, Yan S, Tompkins RG, Rahme LG, Ryan CM. Do standard burn mortality formulae work on a population of severely burned children and adults? Burns. 2015 Aug; 41(5):935-45. PMID: 25922299.
    Citations: 9     Fields:    Translation:Humans
  14. Yan S, Tsurumi A, Que YA, Ryan CM, Bandyopadhaya A, Morgan AA, Flaherty PJ, Tompkins RG, Rahme LG. Prediction of multiple infections after severe burn trauma: a prospective cohort study. Ann Surg. 2015 Apr; 261(4):781-92. PMID: 24950278; PMCID: PMC4284150.
    Citations: 16     Fields:    Translation:HumansCells
  15. Que YA, Hazan R, Strobel B, Maura D, He J, Kesarwani M, Panopoulos P, Tsurumi A, Giddey M, Wilhelmy J, Mindrinos MN, Rahme LG. A quorum sensing small volatile molecule promotes antibiotic tolerance in bacteria. PLoS One. 2013; 8(12):e80140. PMID: 24367477.
    Citations: 27     Fields:    Translation:Cells
  16. Tsurumi A, Dutta P, Dutta P, Shang R, Yan SJ, Sheng R, Li WX. Drosophila Kdm4 demethylases in histone H3 lysine 9 demethylation and ecdysteroid signaling. Sci Rep. 2013 Oct 08; 3:2894. PMID: 24100631.
    Citations: 17     Fields:    Translation:AnimalsCells
  17. Hu X, Dutta P, Tsurumi A, Li J, Wang J, Land H, Li WX. Unphosphorylated STAT5A stabilizes heterochromatin and suppresses tumor growth. Proc Natl Acad Sci U S A. 2013 Jun 18; 110(25):10213-8. PMID: 23733954; PMCID: PMC3690839.
    Citations: 33     Fields:    Translation:HumansAnimalsCells
  18. Gaur K, Li J, Wang D, Dutta P, Yan SJ, Tsurumi A, Land H, Wu G, Li WX. The Birt-Hogg-Dubé tumor suppressor Folliculin negatively regulates ribosomal RNA synthesis. Hum Mol Genet. 2013 Jan 15; 22(2):284-99. PMID: 23077212.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  19. Tsurumi A, Li WX. Global heterochromatin loss: a unifying theory of aging? Epigenetics. 2012 Jul; 7(7):680-8. PMID: 22647267.
    Citations: 66     Fields:    Translation:HumansAnimalsCells
  20. Larson K, Yan SJ, Tsurumi A, Liu J, Zhou J, Gaur K, Guo D, Eickbush TH, Li WX. Heterochromatin formation promotes longevity and represses ribosomal RNA synthesis. PLoS Genet. 2012 Jan; 8(1):e1002473. PMID: 22291607; PMCID: PMC3266895.
    Citations: 113     Fields:    Translation:AnimalsCells
  21. Van Cor-Hosmer SK, Daddacha W, Kelly Z, Tsurumi A, Kennedy EM, Kim B. The impact of molecular manipulation in residue 114 of human immunodeficiency virus type-1 reverse transcriptase on dNTP substrate binding and viral replication. Virology. 2012 Jan 20; 422(2):393-401. PMID: 22153297.
    Citations: 9     Fields:    Translation:HumansCells
  22. Tsurumi A, Xia F, Li J, Larson K, LaFrance R, Li WX. STAT is an essential activator of the zygotic genome in the early Drosophila embryo. PLoS Genet. 2011 May; 7(5):e1002086. PMID: 21637778.
    Citations: 29     Fields:    Translation:AnimalsCells
  23. Xia F, Li J, Hickey GW, Tsurumi A, Larson K, Guo D, Yan SJ, Silver-Morse L, Li WX. Raf activation is regulated by tyrosine 510 phosphorylation in Drosophila. PLoS Biol. 2008 May 20; 6(5):e128. PMID: 18494562.
    Citations: 10     Fields:    Translation:AnimalsCells
  24. Tang Z, Tsurumi A, Alaei S, Wilson C, Chiu C, Oya J, Ngo B. Dsk1p kinase phosphorylates SR proteins and regulates their cellular localization in fission yeast. Biochem J. 2007 Jul 01; 405(1):21-30. PMID: 17362205; PMCID: PMC1925236.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.