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Ana Griciuc, Ph.D.

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  1. R00AG049056 (GRICIUC, ANA) Mar 1, 2017 - Aug 31, 2020
    NIH
    CD33 and Alzheimer's Disease: from Biology to Therapy
    Role: Principal Investigator
  2. K99AG049056 (GRICIUC, ANA) Feb 15, 2015 - Jan 31, 2017
    NIH
    CD33 and Alzheimer's Disease: from Biology to Therapy
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Griciuc A, Tanzi RE. The role of innate immune genes in Alzheimer's disease. Curr Opin Neurol. 2021 Apr 01; 34(2):228-236. PMID: 33560670.
    Citations:    Fields:    
  2. Shoup TM, Griciuc A, Normandin MD, Quinti L, Walsh LV, Dhaynaut M, Moon SH, Guehl NJ, Brugarolas P, Elmaleh DR, Fakhri GE, Tanzi RE. Evaluation of Fluorinated Cromolyn Derivatives as Potential Therapeutics for Alzheimer's Disease. J Alzheimers Dis. 2021 Feb 12. PMID: 33579853.
    Citations:    Fields:    
  3. Griciuc A, Federico AN, Natasan J, Forte AM, McGinty D, Nguyen H, Volak A, LeRoy S, Gandhi S, Lerner EP, Hudry E, Tanzi RE, Maguire CA. Gene therapy for Alzheimer's disease targeting CD33 reduces amyloid beta accumulation and neuroinflammation. Hum Mol Genet. 2020 Oct 10; 29(17):2920-2935. PMID: 32803224.
    Citations: 1     Fields:    
  4. Granucci EJ, Griciuc A, Mueller KA, Mills AN, Le H, Dios AM, McGinty D, Pereira J, Elmaleh D, Berry JD, Paganoni S, Cudkowicz ME, Tanzi RE, Sadri-Vakili G. Cromolyn sodium delays disease onset and is neuroprotective in the SOD1G93A Mouse Model of amyotrophic lateral sclerosis. Sci Rep. 2019 11 27; 9(1):17728. PMID: 31776380.
    Citations: 9     Fields:    Translation:AnimalsCells
  5. Griciuc A, Patel S, Federico AN, Choi SH, Innes BJ, Oram MK, Cereghetti G, McGinty D, Anselmo A, Sadreyev RI, Hickman SE, El Khoury J, Colonna M, Tanzi RE. TREM2 Acts Downstream of CD33 in Modulating Microglial Pathology in Alzheimer's Disease. Neuron. 2019 09 04; 103(5):820-835.e7. PMID: 31301936.
    Citations: 31     Fields:    Translation:AnimalsCells
  6. Zhang C, Griciuc A, Hudry E, Wan Y, Quinti L, Ward J, Forte AM, Shen X, Ran C, Elmaleh DR, Tanzi RE. Cromolyn Reduces Levels of the Alzheimer's Disease-Associated Amyloid ß-Protein by Promoting Microglial Phagocytosis. Sci Rep. 2018 01 18; 8(1):1144. PMID: 29348604.
    Citations: 13     Fields:    Translation:HumansAnimalsCells
  7. Griciuc A, Roux MJ, Merl J, Giangrande A, Hauck SM, Aron L, Ueffing M. Proteomic survey reveals altered energetic patterns and metabolic failure prior to retinal degeneration. J Neurosci. 2014 Feb 19; 34(8):2797-812. PMID: 24553922.
    Citations: 9     Fields:    Translation:AnimalsCells
  8. Griciuc A, Serrano-Pozo A, Parrado AR, Lesinski AN, Asselin CN, Mullin K, Hooli B, Choi SH, Hyman BT, Tanzi RE. Alzheimer's disease risk gene CD33 inhibits microglial uptake of amyloid beta. Neuron. 2013 May 22; 78(4):631-43. PMID: 23623698.
    Citations: 294     Fields:    Translation:HumansAnimalsCells
  9. Griciuc A, Aron L, Ueffing M. Looking into eyes: rhodopsin pathologies in Drosophila. Adv Exp Med Biol. 2012; 723:415-23. PMID: 22183360.
    Citations: 3     Fields:    Translation:AnimalsCells
  10. Griciuc A, Aron L, Ueffing M. ER stress in retinal degeneration: a target for rational therapy? Trends Mol Med. 2011 Aug; 17(8):442-51. PMID: 21620769.
    Citations: 23     Fields:    Translation:HumansAnimalsCells
  11. Griciuc A, Aron L, Roux MJ, Klein R, Giangrande A, Ueffing M. Inactivation of VCP/ter94 suppresses retinal pathology caused by misfolded rhodopsin in Drosophila. PLoS Genet. 2010 Aug 26; 6(8). PMID: 20865169.
    Citations: 36     Fields:    Translation:HumansAnimalsCells
  12. Griciuc A, Aron L, Piccoli G, Ueffing M. Clearance of Rhodopsin(P23H) aggregates requires the ERAD effector VCP. Biochim Biophys Acta. 2010 Mar; 1803(3):424-34. PMID: 20097236.
    Citations: 23     Fields:    Translation:HumansAnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.