Harvard Catalyst Profiles

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Miguel A Prado, Ph.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Lin BC, Phung TH, Higgins NR, Greenslade JE, Prado MA, Finley D, Karbowski M, Polster BM, Monteiro MJ. ALS/FTD mutations in UBQLN2 are linked to mitochondrial dysfunction through loss-of-function in mitochondrial protein import. Hum Mol Genet. 2021 Jun 17; 30(13):1230-1246. PMID: 33891006.
    Citations:    Fields:    
  2. Cao C, Prado MA, Sun L, Rockowitz S, Sliz P, Paulo JA, Finley D, Fleming MD. Maternal Iron Deficiency Modulates Placental Transcriptome and Proteome in Mid-Gestation of Mouse Pregnancy. J Nutr. 2021 05 11; 151(5):1073-1083. PMID: 33693820.
    Citations:    Fields:    Translation:AnimalsCells
  3. Schnell HM, Walsh RM, Rawson S, Kaur M, Bhanu MK, Tian G, Prado MA, Guerra-Moreno A, Paulo JA, Gygi SP, Roelofs J, Finley D, Hanna J. Structures of chaperone-associated assembly intermediates reveal coordinated mechanisms of proteasome biogenesis. Nat Struct Mol Biol. 2021 05; 28(5):418-425. PMID: 33846632.
    Citations: 1     Fields:    Translation:AnimalsCells
  4. Liu Y, Mei Y, Han X, Korobova FV, Prado MA, Yang J, Peng Z, Paulo JA, Gygi SP, Finley D, Ji P. Membrane skeleton modulates erythroid proteome remodeling and organelle clearance. Blood. 2021 01 21; 137(3):398-409. PMID: 33036023.
    Citations:    Fields:    Translation:AnimalsCells
  5. Whiteley AM, Prado MA, de Poot SAH, Paulo JA, Ashton M, Dominguez S, Weber M, Ngu H, Szpyt J, Jedrychowski MP, Easton A, Gygi SP, Kurz T, Monteiro MJ, Brown EJ, Finley D. Global proteomics of Ubqln2-based murine models of ALS. J Biol Chem. 2021 Jan-Jun; 296:100153. PMID: 33277362.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  6. Wu JJ, Cai A, Greenslade JE, Higgins NR, Fan C, Le NTT, Tatman M, Whiteley AM, Prado MA, Dieriks BV, Curtis MA, Shaw CE, Siddique T, Faull RLM, Scotter EL, Finley D, Monteiro MJ. ALS/FTD mutations in UBQLN2 impede autophagy by reducing autophagosome acidification through loss of function. Proc Natl Acad Sci U S A. 2020 06 30; 117(26):15230-15241. PMID: 32513711.
    Citations: 10     Fields:    Translation:HumansAnimalsCells
  7. Cabal-Hierro L, van Galen P, Prado MA, Higby KJ, Togami K, Mowery CT, Paulo JA, Xie Y, Cejas P, Furusawa T, Bustin M, Long HW, Sykes DB, Gygi SP, Finley D, Bernstein BE, Lane AA. Chromatin accessibility promotes hematopoietic and leukemia stem cell activity. Nat Commun. 2020 03 16; 11(1):1406. PMID: 32179749.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  8. Finley D, Prado MA. The Proteasome and Its Network: Engineering for Adaptability. Cold Spring Harb Perspect Biol. 2020 01 02; 12(1). PMID: 30833452.
    Citations: 17     Fields:    Translation:HumansAnimalsCells
  9. Guerra-Moreno A, Prado MA, Ang J, Schnell HM, Micoogullari Y, Paulo JA, Finley D, Gygi SP, Hanna J. Thiol-based direct threat sensing by the stress-activated protein kinase Hog1. Sci Signal. 2019 11 26; 12(609). PMID: 31772124.
    Citations: 1     Fields:    Translation:AnimalsCells
  10. Massa F, Tammaro R, Prado MA, Cesana M, Lee BH, Finley D, Franco B, Morleo M. The deubiquitinating enzyme Usp14 controls ciliogenesis and Hedgehog signaling. Hum Mol Genet. 2019 03 01; 28(5):764-777. PMID: 30388222.
    Citations: 10     Fields:    Translation:AnimalsCells
  11. Bretones G, Álvarez MG, Arango JR, Rodríguez D, Nadeu F, Prado MA, Valdés-Mas R, Puente DA, Paulo JA, Delgado J, Villamor N, López-Guillermo A, Finley DJ, Gygi SP, Campo E, Quesada V, López-Otín C. Altered patterns of global protein synthesis and translational fidelity in RPS15-mutated chronic lymphocytic leukemia. Blood. 2018 11 29; 132(22):2375-2388. PMID: 30181176.
    Citations: 13     Fields:    Translation:HumansCells
  12. Fraile JM, Campos-Iglesias D, Rodríguez F, Astudillo A, Vilarrasa-Blasi R, Verdaguer-Dot N, Prado MA, Paulo JA, Gygi SP, Martín-Subero JI, Freije JMP, López-Otín C. Loss of the deubiquitinase USP36 destabilizes the RNA helicase DHX33 and causes preimplantation lethality in mice. J Biol Chem. 2018 02 09; 293(6):2183-2194. PMID: 29273634.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  13. Boselli M, Lee BH, Robert J, Prado MA, Min SW, Cheng C, Silva MC, Seong C, Elsasser S, Hatle KM, Gahman TC, Gygi SP, Haggarty SJ, Gan L, King RW, Finley D. An inhibitor of the proteasomal deubiquitinating enzyme USP14 induces tau elimination in cultured neurons. J Biol Chem. 2017 11 24; 292(47):19209-19225. PMID: 28972160.
    Citations: 42     Fields:    Translation:AnimalsCells
  14. Whiteley AM, Prado MA, Peng I, Abbas AR, Haley B, Paulo JA, Reichelt M, Katakam A, Sagolla M, Modrusan Z, Lee DY, Roose-Girma M, Kirkpatrick DS, McKenzie BS, Gygi SP, Finley D, Brown EJ. Ubiquilin1 promotes antigen-receptor mediated proliferation by eliminating mislocalized mitochondrial proteins. Elife. 2017 09 21; 6. PMID: 28933694.
    Citations: 13     Fields:    Translation:HumansAnimalsCells
  15. Nguyen AT, Prado MA, Schmidt PJ, Sendamarai AK, Wilson-Grady JT, Min M, Campagna DR, Tian G, Shi Y, Dederer V, Kawan M, Kuehnle N, Paulo JA, Yao Y, Weiss MJ, Justice MJ, Gygi SP, Fleming MD, Finley D. UBE2O remodels the proteome during terminal erythroid differentiation. Science. 2017 08 04; 357(6350). PMID: 28774900.
    Citations: 44     Fields:    Translation:HumansAnimalsCells
  16. Quirós PM, Prado MA, Zamboni N, D'Amico D, Williams RW, Finley D, Gygi SP, Auwerx J. Multi-omics analysis identifies ATF4 as a key regulator of the mitochondrial stress response in mammals. J Cell Biol. 2017 07 03; 216(7):2027-2045. PMID: 28566324.
    Citations: 190     Fields:    Translation:HumansAnimalsCells
  17. Rose CM, Isasa M, Ordureau A, Prado MA, Beausoleil SA, Jedrychowski MP, Finley DJ, Harper JW, Gygi SP. Highly Multiplexed Quantitative Mass Spectrometry Analysis of Ubiquitylomes. Cell Syst. 2016 10 26; 3(4):395-403.e4. PMID: 27667366.
    Citations: 48     Fields:    Translation:AnimalsCells
  18. Lee BH, Lu Y, Prado MA, Shi Y, Tian G, Sun S, Elsasser S, Gygi SP, King RW, Finley D. USP14 deubiquitinates proteasome-bound substrates that are ubiquitinated at multiple sites. Nature. 2016 Apr 21; 532(7599):398-401. PMID: 27074503.
    Citations: 69     Fields:    Translation:HumansAnimalsCells
  19. Cabal-Hierro L, Rodríguez M, Artime N, Iglesias J, Ugarte L, Prado MA, Lazo PS. TRAF-mediated modulation of NF-kB AND JNK activation by TNFR2. Cell Signal. 2014 Dec; 26(12):2658-66. PMID: 25152365.
    Citations: 19     Fields:    Translation:HumansCells
  20. Cabal-Hierro L, Artime N, Iglesias J, Prado MA, Ugarte-Gil L, Casado P, Fernández-García B, Darnay BG, Lazo PS. A TRAF2 binding independent region of TNFR2 is responsible for TRAF2 depletion and enhancement of cytotoxicity driven by TNFR1. Oncotarget. 2014 Jan 15; 5(1):224-36. PMID: 24318359.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  21. Fernandez-Garcia B, Casado P, Prado MA, Ugarte-Gil LJ, Artime N, Cabal-Hierro L, Calvo E, López JA, Ramos S, Lazo PS. Proteomic analysis of annexin A2 phosphorylation induced by microtubule interfering agents and kinesin spindle protein inhibitors. J Proteome Res. 2010 Sep 03; 9(9):4649-60. PMID: 20597553.
    Citations: 1     Fields:    Translation:HumansCells
  22. Casado P, Prado MA, Zuazua-Villar P, Del Valle E, Artime N, Cabal-Hierro L, Rupérez P, Burlingame AL, Lazo PS, Ramos S. Microtubule interfering agents and KSP inhibitors induce the phosphorylation of the nuclear protein p54(nrb), an event linked to G2/M arrest. J Proteomics. 2009 Jan 30; 71(6):592-600. PMID: 18832053.
    Citations: 3     Fields:    Translation:HumansCells
  23. Prado MA, Casado P, Zuazua-Villar P, del Valle E, Artime N, Cabal-Hierro L, Martínez-Campa CM, Lazo PS, Ramos S. Phosphorylation of human eukaryotic elongation factor 1Bgamma is regulated by paclitaxel. Proteomics. 2007 Sep; 7(18):3299-304. PMID: 17708594.
    Citations:    Fields:    Translation:HumansCells
  24. Casado P, Zuazua-Villar P, Prado MA, Valle ED, Iglesias JM, Martínez-Campa C, Lazo PS, Ramos S. Characterization of HSP27 phosphorylation induced by microtubule interfering agents: implication of p38 signalling pathway. Arch Biochem Biophys. 2007 May 01; 461(1):123-9. PMID: 17367746.
    Citations: 5     Fields:    Translation:HumansCells
  25. Prado MA, Miró RL, Leal IM, Vargas J, Dorrego EJ. Intramuscular myxoma: differential diagnosis and review of the literature. Orthopedics. 2002 Nov; 25(11):1297-9. PMID: 12452352.
    Citations: 5     Fields:    Translation:Humans
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.