Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Edward Thomas Ryan, D.T.M.&H., M.D.

Title
Institution
Department
Address
Phone
Fax
Profile Picture
Other Positions
Title
Institution
Department

Overview
Edward T. Ryan, M.D. is the Director of Global Infectious Diseases, Massachusetts General Hospital, Boston, MA, Professor of Medicine, Harvard Medical School, and Professor of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health. Dr. Ryan received his Bachelor's degree in Biochemical Sciences from Princeton University, and a Doctorate in Medicine from Harvard University. He performed medical residency and fellowship training in infectious diseases at the Massachusetts General Hospital. Dr. Ryan received additional training in tropical medicine and infectious diseases at the London School of Hygiene & Tropical Medicine, was a Fellow in Human Rights & Medicine, Columbia University, and was an International Fellow, International Centre for Diarrhoeal Disease Research (ICDDR, B), Dhaka, Bangladesh.

Dr. Ryan has served on expert and advisory committees for the Institute of Medicine-National Academy of Sciences, U.S. Centers for Disease Control & Prevention, chaired the Clinical Research and Field Studies of Infectious Diseases Study section of the US NIH from 2006-2008, chaired the Standards and Treatment Guidelines Committee of the American Society of Tropical Medicine & Hygiene (ASTMH) 2010-2018, and served as ASTMH President from 2009-2010. Dr. Ryan has been elected to Fellowship of the American College of Physicians, the Infectious Diseases Society of America, the American Society of Tropical Medicine and Hygiene, and the American Academy of Microbiology. Dr Ryan has published over 300 peer-reviewed journal articles and book chapters on global infectious diseases, enteric infections, vaccines, and tropical medicine. Dr. Ryan is a Senior Editor of Hunter's Tropical Medicine, and a Medical Editor of the Centers for Disease Control and Prevention Yellow Book.

Research:

Our research focuses on host-bacterial pathogen interactions and immune responses, with a particular focus on enteric infections and the development of vaccines protective against enteric infections, and development of diagnostic assays. Specific focus areas include Vibrio cholerae, the cause of cholera; Salmonella enterica, the causes of typhoid and paratyphoid fever; and Shigella spp, the cause of dysentery. We work in collaborative efforts with researchers at the International Centre for Diarrhoeal Disease Research in Dhaka Bangladesh (ICDDR,B), as well as with colleagues in Nepal, Pakistan, Haiti, and South Sudan.

Immune responses during cholera

In a collaborative effort with researchers at the International Centre for Diarrhoeal Disease Research in Dhaka, Bangladesh (ICDDR,B), we are evaluating immune responses in humans infected with Vibrio cholerae, the cause of cholera. V. cholerae is endemic in over 50 countries, infects approximately 3-5 million individuals globally, and results in the death of approximately 100,000 individuals each year. Individuals most affected by cholera are those most impoverished, especially those lacking safe water and sanitary facilities, as well as individuals displaced by war, famine, disasters, and conflict. Cholera can be explosively epidemic, and the global burden of cholera may well increase with climate change, severe weather events, and increasing urbanization. V. cholerae is a human-restricted infection, and current cholera vaccines provide relatively short-term protection against disease. The mediators of protective immunity against cholera are poorly understood. To address this, we are applying a number of high throughput and platform technologies to assess innate and adaptive immune responses in humans with cholera and their household contacts, stratifying responses in the latter by subsequent protection from disease, and comparing responses in the former to those that occur in recipients of current cholera vaccines. The goal of these studies is to identify the mediators of protection against cholera, in order to advance improved prevention strategies, as well as to advance vaccine development and deployment.

Host-pathogen interactions during typhoid fever

In a collaborative effort with researchers at the International Centre for Diarrhoeal Disease Research in Dhaka, Bangladesh (ICDDR,B), we are evaluating host-pathogen interactions and immune responses in humans infected with Salmonella enterica serotype Typhi (the cause of typhoid fever) and S. Paratyphi (the cause of paratyphoid fever). Together, S. Typhi and S. Paratyphi cause approximately 20 million cases of enteric fever world-wide, resulting in approximately 200,000 deaths each year. Most of these deaths occur in impoverished children and young adults. Although usually caused by S. Typhi, one in four cases of enteric fever is caused by S. Paratyphi in many areas of the world. S. Typhi and S. Paratyphi are particularly common among urban residents in informal settlements and slums, although any individual lacking safe water and sanitary facilities is at risk of infection. Vaccines against S. Typhi provide only 50-60% protection against disease for 2-5 years, and, at present, there is no commercially available vaccine against S. Paratyphi. There is also no good point-of-care test to diagnose individuals with enteric fever, and S. Typhi and S. Paratyphi are becoming increasingly resistant to antimicrobial agents.To address this, we are evaluating host-pathogen interactions directly in humans infected with S. Typhi and S. Paratyphi. We are applying a number of technologies to evaluate innate and adaptive immune responses directly in humans infected with S. Typhi and S. Paratyphi in Bangladesh, and we are evaluating bacterial responses in humans during these human-restricted infections. The goal of these studies is to develop improved diagnostic assays, antimicrobial agents, and preventative strategies against these infections.

Immunization approaches for enteric infection

A fundamental challenge facing many enteric and mucosal vaccines is their inability to induce long-term protective immunity. Many of these vaccines may not be prominent inducers of memory cells, which play critical roles in mediating long-term protection against disease. Using our analysis of memory B and T cell induction during wild-type human enteric infection in Bangladesh, we are evaluating the ability of a number of vaccination approaches and strategies to induce long-term memory responses protective against mucosal and enteric infections, including development of enteric conjugate vaccines, and analysis of oral-transcutaneous prime-boosting approaches.

Global TravEpinet (GTEN)

To extend our analysis of infections associated with living in, traveling through, or immigrating from resource-limited areas, we also work with the U.S. Centers for Disease Control and Prevention through the GTEN (Global TravEpiNet; Global Travelers' Epidemiology Network) Program. GTEN's mission is to advance the health of American residents who travel internationally, as well as to lessen the likelihood of disease importation into home communities. GTEN-relate resources are available at Heading Home Healthy. Through this program, we have been able to address COVID-19, an illness introduced into U.S. populations through travel. Our efforts have focused on understanding diagnostic assays and transmission dynamics to assist in control measures. We have assessed immune responses during SARS-CoV-2 infection, including duration and cross reactivity with other coronaviridae, characterized immune responses during naturally acquired disease to inform vaccine development, and phylogenetically typed viral strains to assess introduction and transmission of SARS-CoV-2 at population levels.

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Fajnzylber J, Regan J, Coxen K, Corry H, Wong C, Rosenthal A, Worrall D, Giguel F, Piechocka-Trocha A, Atyeo C, Fischinger S, Chan A, Flaherty KT, Hall K, Dougan M, Ryan ET, Gillespie E, Chishti R, Li Y, Jilg N, Hanidziar D, Baron RM, Baden L, Tsibris AM, Armstrong KA, Kuritzkes DR, Alter G, Walker BD, Yu X, Li JZ. SARS-CoV-2 viral load is associated with increased disease severity and mortality. Nat Commun. 2020 10 30; 11(1):5493. PMID: 33127906.
    Citations:    
  2. Iyer AS, Jones FK, Nodoushani A, Kelly M, Becker M, Slater D, Mills R, Teng E, Kamruzzaman M, Garcia-Beltran WF, Astudillo M, Yang D, Miller TE, Oliver E, Fischinger S, Atyeo C, Iafrate AJ, Calderwood SB, Lauer SA, Yu J, Li Z, Feldman J, Hauser BM, Caradonna TM, Branda JA, Turbett SE, LaRocque RC, Mellon G, Barouch DH, Schmidt AG, Azman AS, Alter G, Ryan ET, Harris JB, Charles RC. Persistence and decay of human antibody responses to the receptor binding domain of SARS-CoV-2 spike protein in COVID-19 patients. Sci Immunol. 2020 10 08; 5(52). PMID: 33033172.
    Citations:    Fields:    
  3. Shirin T, Bhuiyan TR, Charles RC, Amin S, Bhuiyan I, Kawser Z, Rahat A, Alam AN, Sultana S, Aleem MA, Khan MH, Khan SR, LaRocque RC, Calderwood SB, Ryan ET, Slater DM, Banu S, Clemens J, Harris JB, Flora MS, Qadri F. Antibody responses after COVID-19 infection in patients who are mildly symptomatic or asymptomatic in Bangladesh. Int J Infect Dis. 2020 Oct 05; 101:220-225. PMID: 33031941.
    Citations:    Fields:    
  4. Yonker LM, Neilan AM, Bartsch Y, Patel AB, Regan J, Arya P, Gootkind E, Park G, Hardcastle M, St John A, Appleman L, Chiu ML, Fialkowski A, De La Flor D, Lima R, Bordt EA, Yockey LJ, D'Avino P, Fischinger S, Shui JE, Lerou PH, Bonventre JV, Yu XG, Ryan ET, Bassett IV, Irimia D, Edlow AG, Alter G, Li JZ, Fasano A. Reply. J Pediatr. 2020 Sep 21. PMID: 32971143.
    Citations:    Fields:    
  5. Yonker LM, Neilan AM, Bartsch Y, Patel AB, Regan J, Arya P, Gootkind E, Park G, Hardcastle M, St John A, Appleman L, Chiu ML, Fialkowski A, De la Flor D, Lima R, Bordt EA, Yockey LJ, D'Avino P, Fischinger S, Shui JE, Lerou PH, Bonventre JV, Yu XG, Ryan ET, Bassett IV, Irimia D, Edlow AG, Alter G, Li JZ, Fasano A. Reply. J Pediatr. 2020 Sep 18. PMID: 32956696.
    Citations:    Fields:    
  6. Norman M, Gilboa T, Ogata AF, Maley AM, Cohen L, Busch EL, Lazarovits R, Mao CP, Cai Y, Zhang J, Feldman JE, Hauser BM, Caradonna TM, Chen B, Schmidt AG, Alter G, Charles RC, Ryan ET, Walt DR. Ultrasensitive high-resolution profiling of early seroconversion in patients with COVID-19. Nat Biomed Eng. 2020 Sep 18. PMID: 32948854.
    Citations: 1     Fields:    
  7. Ogata AF, Maley AM, Wu C, Gilboa T, Norman M, Lazarovits R, Mao CP, Newton G, Chang M, Nguyen K, Kamkaew M, Zhu Q, Gibson TE, Ryan ET, Charles RC, Marasco WA, Walt DR. Ultra-sensitive Serial Profiling of SARS-CoV-2 Antigens and Antibodies in Plasma to Understand Disease Progression in COVID-19 Patients with Severe Disease. Clin Chem. 2020 Sep 08. PMID: 32897389.
    Citations:    Fields:    
  8. Loos C, Atyeo C, Fischinger S, Burke J, Slein MD, Streeck H, Lauffenburger D, Ryan ET, Charles RC, Alter G. Evolution of Early SARS-CoV-2 and Cross-Coronavirus Immunity. mSphere. 2020 09 02; 5(5). PMID: 32878931.
    Citations:    Fields:    Translation:HumansCellsPHPublic Health
  9. Anahtar MN, Shaw B, Slater D, Byrne EH, Botti-Lodovico Y, Adams G, Schaffner SF, Eversley JS, McGrath G, Gogakos T, Lennerz J, Marble HD, Ritterhouse LL, Batten J, Georgantas NZ, Pellerin R, Signorelli S, Thierauf J, Kemball M, Happi C, Grant DS, Ndiaye D, Siddle KJ, Mehta SB, Harris JB, Ryan ET, Pierce VM, LaRocque RC, Lemieux J, Sabeti P, Rosenberg E, Branda J, Turbett SE. Development of a qualitative real-time RT-PCR assay for the detection of SARS-CoV-2: A guide and case study in setting up an emergency-use, laboratory-developed molecular assay. medRxiv. 2020 Sep 01. PMID: 32909014.
    Citations:    
  10. Bhuiyan MS, Kalsy A, Arifuzzaman M, Charles RC, Harris JB, Calderwood SB, Qadri F, Ryan ET. Transcutaneous Vaccination with Conjugate Typhoid Vaccine Vi-DT Induces Systemic, Mucosal, and Memory Anti-Polysaccharide Responses. Am J Trop Med Hyg. 2020 09; 103(3):1032-1038. PMID: 32720632.
    Citations:    Fields:    
  11. Miller TE, Garcia Beltran WF, Bard AZ, Gogakos T, Anahtar MN, Astudillo MG, Yang D, Thierauf J, Fisch AS, Mahowald GK, Fitzpatrick MJ, Nardi V, Feldman J, Hauser BM, Caradonna TM, Marble HD, Ritterhouse LL, Turbett SE, Batten J, Georgantas NZ, Alter G, Schmidt AG, Harris JB, Gelfand JA, Poznansky MC, Bernstein BE, Louis DN, Dighe A, Charles RC, Ryan ET, Branda JA, Pierce VM, Murali MR, Iafrate AJ, Rosenberg ES, Lennerz JK. Clinical sensitivity and interpretation of PCR and serological COVID-19 diagnostics for patients presenting to the hospital. FASEB J. 2020 Aug 28. PMID: 32856766.
    Citations: 1     Fields:    
  12. Whitman JD, Hiatt J, Mowery CT, Shy BR, Yu R, Yamamoto TN, Rathore U, Goldgof GM, Whitty C, Woo JM, Gallman AE, Miller TE, Levine AG, Nguyen DN, Bapat SP, Balcerek J, Bylsma SA, Lyons AM, Li S, Wong AW, Gillis-Buck EM, Steinhart ZB, Lee Y, Apathy R, Lipke MJ, Smith JA, Zheng T, Boothby IC, Isaza E, Chan J, Acenas DD, Lee J, Macrae TA, Kyaw TS, Wu D, Ng DL, Gu W, York VA, Eskandarian HA, Callaway PC, Warrier L, Moreno ME, Levan J, Torres L, Farrington LA, Loudermilk RP, Koshal K, Zorn KC, Garcia-Beltran WF, Yang D, Astudillo MG, Bernstein BE, Gelfand JA, Ryan ET, Charles RC, Iafrate AJ, Lennerz JK, Miller S, Chiu CY, Stramer SL, Wilson MR, Manglik A, Ye CJ, Krogan NJ, Anderson MS, Cyster JG, Ernst JD, Wu AHB, Lynch KL, Bern C, Hsu PD, Marson A. Evaluation of SARS-CoV-2 serology assays reveals a range of test performance. Nat Biotechnol. 2020 10; 38(10):1174-1183. PMID: 32855547.
    Citations: 4     Fields:    Translation:HumansCellsPHPublic Health
  13. Gandhi AR, Rao SR, Chen LH, Nelson MD, Ryan ET, LaRocque RC, Hyle EP. Prescribing Patterns of Antibiotics for the Self-Treatment of Travelers' Diarrhea in Global TravEpiNet, 2009-2018. Open Forum Infect Dis. 2020 Oct; 7(10):ofaa376. PMID: 33072808.
    Citations:    
  14. Lemieux J, Siddle KJ, Shaw BM, Loreth C, Schaffner S, Gladden-Young A, Adams G, Fink T, Tomkins-Tinch CH, Krasilnikova LA, Deruff KC, Rudy M, Bauer MR, Lagerborg KA, Normandin E, Chapman SB, Reilly SK, Anahtar MN, Lin AE, Carter A, Myhrvold C, Kemball M, Chaluvadi S, Cusick C, Flowers K, Neumann A, Cerrato F, Farhat M, Slater D, Harris JB, Branda J, Hooper D, Gaeta JM, Baggett TP, O'Connell J, Gnirke A, Lieberman TD, Philippakis A, Burns M, Brown C, Luban J, Ryan ET, Turbett SE, LaRocque RC, Hanage WP, Gallagher G, Madoff LC, Smole S, Pierce VM, Rosenberg ES, Sabeti P, Park DJ, MacInnis BL. Phylogenetic analysis of SARS-CoV-2 in the Boston area highlights the role of recurrent importation and superspreading events. medRxiv. 2020 Aug 25. PMID: 32869040.
    Citations:    
  15. Yonker LM, Neilan AM, Bartsch Y, Patel AB, Regan J, Arya P, Gootkind E, Park G, Hardcastle M, St John A, Appleman L, Chiu ML, Fialkowski A, De la Flor D, Lima R, Bordt EA, Yockey LJ, D'Avino P, Fischinger S, Shui JE, Lerou PH, Bonventre JV, Yu XG, Ryan ET, Bassett IV, Irimia D, Edlow AG, Alter G, Li JZ, Fasano A. Pediatric Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2): Clinical Presentation, Infectivity, and Immune Responses. J Pediatr. 2020 Dec; 227:45-52.e5. PMID: 32827525.
    Citations: 9     Fields:    
  16. Atyeo C, Fischinger S, Zohar T, Slein MD, Burke J, Loos C, McCulloch DJ, Newman KL, Wolf C, Yu J, Shuey K, Feldman J, Hauser BM, Caradonna T, Schmidt AG, Suscovich TJ, Linde C, Cai Y, Barouch D, Ryan ET, Charles RC, Lauffenburger D, Chu H, Alter G. Distinct Early Serological Signatures Track with SARS-CoV-2 Survival. Immunity. 2020 09 15; 53(3):524-532.e4. PMID: 32783920.
    Citations: 8     Fields:    Translation:HumansCellsPHPublic Health
  17. Iyer AS, Jones FK, Nodoushani A, Kelly M, Becker M, Slater D, Mills R, Teng E, Kamruzzaman M, Garcia-Beltran WF, Astudillo M, Yang D, Miller TE, Oliver E, Fischinger S, Atyeo C, Iafrate AJ, Calderwood SB, Lauer SA, Yu J, Li Z, Feldman J, Hauser BM, Caradonna TM, Branda JA, Turbett SE, LaRocque RC, Mellon G, Barouch DH, Schmidt AG, Azman AS, Alter G, Ryan ET, Harris JB, Charles RC. Dynamics and significance of the antibody response to SARS-CoV-2 infection. medRxiv. 2020 Jul 20. PMID: 32743600.
    Citations:    
  18. Levade I, Saber MM, Midani F, Chowdhury F, Khan AI, Begum YA, Ryan ET, David LA, Calderwood SB, Harris JB, LaRocque RC, Qadri F, Shapiro BJ, Weil AA. Predicting Vibrio cholerae infection and disease severity using metagenomics in a prospective cohort study. J Infect Dis. 2020 Jul 01. PMID: 32610345.
    Citations:    Fields:    
  19. Xu P, Korcová J, Baráth P, Cížová A, Valáriková J, Qadri F, Kelly M, O'Connor RD, Ryan ET, Bystrický S, Kovác P. Corrigendum: Isolation, Purification, Characterization and Direct Conjugation of the Lipid A-Free Lipopolysaccharide of Vibrio cholerae O139. Chemistry. 2020 07 17; 26(40):8828. PMID: 32691457.
    Citations:    Fields:    
  20. Kumar S, Nodoushani A, Khanam F, DeCruz AT, Lambotte P, Scott R, Bogoch II, Vaidya K, Calderwood SB, Bhuiyan TR, Esfandiari J, Ryan ET, Qadri F, Andrews JR, Charles RC. Evaluation of a Rapid Point-of-Care Multiplex Immunochromatographic Assay for the Diagnosis of Enteric Fever. mSphere. 2020 06 10; 5(3). PMID: 32522777.
    Citations:    Fields:    
  21. Sui HY, Weil AA, Nuwagira E, Qadri F, Ryan ET, Mezzari MP, Phipatanakul W, Lai PS. Impact of DNA Extraction Method on Variation in Human and Built Environment Microbial Community and Functional Profiles Assessed by Shotgun Metagenomics Sequencing. Front Microbiol. 2020; 11:953. PMID: 32528434.
    Citations:    
  22. Whitman JD, Hiatt J, Mowery CT, Shy BR, Yu R, Yamamoto TN, Rathore U, Goldgof GM, Whitty C, Woo JM, Gallman AE, Miller TE, Levine AG, Nguyen DN, Bapat SP, Balcerek J, Bylsma SA, Lyons AM, Li S, Wong AW, Gillis-Buck EM, Steinhart ZB, Lee Y, Apathy R, Lipke MJ, Smith JA, Zheng T, Boothby IC, Isaza E, Chan J, Acenas DD, Lee J, Macrae TA, Kyaw TS, Wu D, Ng DL, Gu W, York VA, Eskandarian HA, Callaway PC, Warrier L, Moreno ME, Levan J, Torres L, Farrington LA, Loudermilk R, Koshal K, Zorn KC, Garcia-Beltran WF, Yang D, Astudillo MG, Bernstein BE, Gelfand JA, Ryan ET, Charles RC, Iafrate AJ, Lennerz JK, Miller S, Chiu CY, Stramer SL, Wilson MR, Manglik A, Ye CJ, Krogan NJ, Anderson MS, Cyster JG, Ernst JD, Wu AHB, Lynch KL, Bern C, Hsu PD, Marson A. Test performance evaluation of SARS-CoV-2 serological assays. medRxiv. 2020 May 17. PMID: 32511497.
    Citations:    
  23. Norman M, Gilboa T, Ogata AF, Maley AM, Cohen L, Cai Y, Zhang J, Feldman JE, Hauser BM, Caradonna TM, Chen B, Schmidt AG, Alter G, Charles RC, Ryan ET, Walt DR. Ultra-Sensitive High-Resolution Profiling of Anti-SARS-CoV-2 Antibodies for Detecting Early Seroconversion in COVID-19 Patients. medRxiv. 2020 May 02. PMID: 32511657.
    Citations:    
  24. Mellon G, Turbett SE, Worby C, Oliver E, Walker AT, Walters M, Kelly P, Leung DT, Knouse M, Hagmann S, Earl A, Ryan ET, LaRocque RC. Acquisition of Antibiotic-Resistant Bacteria by U.S. International Travelers. N Engl J Med. 2020 04 02; 382(14):1372-1374. PMID: 32242366.
    Citations: 1     Fields:    Translation:HumansCells
  25. Ou L, Kong WP, Chuang GY, Ghosh M, Gulla K, O'Dell S, Varriale J, Barefoot N, Changela A, Chao CW, Cheng C, Druz A, Kong R, McKee K, Rawi R, Sarfo EK, Schön A, Shaddeau A, Tsybovsky Y, Verardi R, Wang S, Wanninger TG, Xu K, Yang GJ, Zhang B, Zhang Y, Zhou T, Arnold FJ, Doria-Rose NA, Lei QP, Ryan ET, Vann WF, Mascola JR, Kwong PD. Preclinical Development of a Fusion Peptide Conjugate as an HIV Vaccine Immunogen. Sci Rep. 2020 02 20; 10(1):3032. PMID: 32080235.
    Citations: 1     Fields:    
  26. Hyle EP, Rao SR, Bangs AC, Gastañaduy P, Fiebelkorn AP, Hagmann SHF, Walker AT, Walensky RP, Ryan ET, LaRocque RC. Clinical Practices for Measles-Mumps-Rubella Vaccination Among US Pediatric International Travelers. JAMA Pediatr. 2020 02 01; 174(2):e194515. PMID: 31816033.
    Citations:    Fields:    
  27. Hossain M, Islam K, Kelly M, Mayo Smith LM, Charles RC, Weil AA, Bhuiyan TR, Kovác P, Xu P, Calderwood SB, Simon JK, Chen WH, Lock M, Lyon CE, Kirkpatrick BD, Cohen M, Levine MM, Gurwith M, Leung DT, Azman AS, Harris JB, Qadri F, Ryan ET. Immune responses to O-specific polysaccharide (OSP) in North American adults infected with Vibrio cholerae O1 Inaba. PLoS Negl Trop Dis. 2019 11; 13(11):e0007874. PMID: 31743334.
    Citations: 1     Fields:    Translation:HumansCells
  28. Yates JA, Rao SR, Walker AT, Esposito DH, Sotir M, LaRocque RC, Ryan ET. Characteristics and preparation of the last-minute traveler: analysis of vaccine usage in the Global TravEpiNet Consortium. J Travel Med. 2019 09 02; 26(6). PMID: 31044254.
    Citations: 2     Fields:    Translation:Humans
  29. Weil AA, Ellis CN, Debela MD, Bhuiyan TR, Rashu R, Bourque DL, Khan AI, Chowdhury F, LaRocque RC, Charles RC, Ryan ET, Calderwood SB, Qadri F, Harris JB. Posttranslational Regulation of IL-23 Production Distinguishes the Innate Immune Responses to Live Toxigenic versus Heat-Inactivated Vibrio cholerae. mSphere. 2019 08 21; 4(4). PMID: 31434744.
    Citations: 1     Fields:    Translation:HumansCells
  30. Xu P, Korcová J, Baráth P, Cížová A, Valáriková J, Qadri F, Kelly M, O'Connor RD, Ryan ET, Bystrický S, Kovác P. Isolation, Purification, Characterization and Direct Conjugation of the Lipid A-Free Lipopolysaccharide of Vibrio cholerae O139. Chemistry. 2019 10 08; 25(56):12946-12956. PMID: 31306528.
    Citations: 1     Fields:    Translation:Cells
  31. Akter A, Dash P, Aktar A, Jahan SR, Afrin S, Basher SR, Hakim A, Lisa AK, Chowdhury F, Khan AI, Xu P, Charles RC, Kelly M, Kovác P, Harris JB, Bhuiyan TR, Calderwood SB, Ryan ET, Qadri F. Induction of systemic, mucosal and memory antibody responses targeting Vibrio cholerae O1 O-specific polysaccharide (OSP) in adults following oral vaccination with an oral killed whole cell cholera vaccine in Bangladesh. PLoS Negl Trop Dis. 2019 08; 13(8):e0007634. PMID: 31369553.
    Citations:    Fields:    Translation:HumansCellsPHPublic Health
  32. Hyle EP, Fields NF, Fiebelkorn AP, Walker AT, Gastañaduy P, Rao SR, Ryan ET, LaRocque RC, Walensky RP. The Clinical Impact and Cost-effectiveness of Measles-Mumps-Rubella Vaccination to Prevent Measles Importations Among International Travelers From the United States. Clin Infect Dis. 2019 07 02; 69(2):306-315. PMID: 30312374.
    Citations: 1     Fields:    Translation:Humans
  33. Sit B, Zhang T, Fakoya B, Akter A, Biswas R, Ryan ET, Waldor MK. Oral immunization with a probiotic cholera vaccine induces broad protective immunity against Vibrio cholerae colonization and disease in mice. PLoS Negl Trop Dis. 2019 05; 13(5):e0007417. PMID: 31150386.
    Citations: 1     Fields:    Translation:HumansAnimalsCellsPHPublic Health
  34. Turbett SE, Desrosiers L, Andrews-Dunleavey C, Becker M, Walker AT, Esposito D, Woodworth KR, Branda JA, Rosenberg E, Ryan ET, LaRocque R. Evaluation of a Screening Method for the Detection of Colistin-Resistant Enterobacteriaceae in Stool. Open Forum Infect Dis. 2019 Jun; 6(6):ofz211. PMID: 31211157.
    Citations:    
  35. Pfister HB, Kelly M, Qadri F, Ryan ET, Kovác P. Synthesis of glycocluster-containing conjugates for a vaccine against cholera. Org Biomol Chem. 2019 04 17; 17(16):4049-4060. PMID: 30950473.
    Citations:    Fields:    Translation:HumansCells
  36. Andrews JR, Khanam F, Rahman N, Hossain M, Bogoch II, Vaidya K, Kelly M, Calderwood SB, Bhuiyan TR, Ryan ET, Qadri F, Charles RC. Plasma Immunoglobulin A Responses Against 2 Salmonella Typhi Antigens Identify Patients With Typhoid Fever. Clin Infect Dis. 2019 03 05; 68(6):949-955. PMID: 30020426.
    Citations: 5     Fields:    Translation:HumansCells
  37. Azman AS, Lessler J, Luquero FJ, Bhuiyan TR, Khan AI, Chowdhury F, Kabir A, Gurwith M, Weil AA, Harris JB, Calderwood SB, Ryan ET, Qadri F, Leung DT. Estimating cholera incidence with cross-sectional serology. Sci Transl Med. 2019 02 20; 11(480). PMID: 30787170.
    Citations: 4     Fields:    Translation:Humans
  38. Ritter AS, Chowdhury F, Franke MF, Becker RL, Bhuiyan TR, Khan AI, Saha NC, Ryan ET, Calderwood SB, LaRocque RC, Harris JB, Qadri F, Weil AA. Vibriocidal Titer and Protection From Cholera in Children. Open Forum Infect Dis. 2019 Apr; 6(4):ofz057. PMID: 30997364.
    Citations: 3     
  39. Falkard B, Charles RC, Matias WR, Mayo-Smith LM, Jerome JG, Offord ES, Xu P, Kovác P, Ryan ET, Qadri F, Franke MF, Ivers LC, Harris JB. Bivalent oral cholera vaccination induces a memory B cell response to the V. cholerae O1-polysaccharide antigen in Haitian adults. PLoS Negl Trop Dis. 2019 01; 13(1):e0007057. PMID: 30703094.
    Citations: 1     Fields:    Translation:HumansCellsPHPublic Health
  40. Chen ST, Cahalane AM, Ryan ET, Foreman RK. Case 2-2019: A 36-Year-Old Man with Rash, Abdominal Pain, and Lymphadenopathy. N Engl J Med. 2019 Jan 17; 380(3):275-283. PMID: 30650323.
    Citations: 1     Fields:    Translation:Humans
  41. Chatham-Stephens K, Medalla F, Hughes M, Appiah GD, Aubert RD, Caidi H, Angelo KM, Walker AT, Hatley N, Masani S, Nash J, Belko J, Ryan ET, Mintz E, Friedman CR. Emergence of Extensively Drug-Resistant Salmonella Typhi Infections Among Travelers to or from Pakistan - United States, 2016-2018. MMWR Morb Mortal Wkly Rep. 2019 Jan 11; 68(1):11-13. PMID: 30629573.
    Citations: 13     Fields:    Translation:HumansCells
  42. Rashu R, Bhuiyan TR, Hoq MR, Hossain L, Paul A, Khan AI, Chowdhury F, Harris JB, Ryan ET, Calderwood SB, Weil AA, Qadri F. Cognate T and B cell interaction and association of follicular helper T cells with B cell responses in Vibrio cholerae O1 infected Bangladeshi adults. Microbes Infect. 2019 Apr - May; 21(3-4):176-183. PMID: 30580014.
    Citations: 1     Fields:    Translation:HumansCells
  43. Andrews JR, Vaidya K, Bern C, Tamrakar D, Wen S, Madhup S, Shrestha R, Karmacharya B, Amatya B, Koju R, Adhikari SR, Hohmann E, Ryan ET, Bogoch II. High Rates of Enteric Fever Diagnosis and Lower Burden of Culture-Confirmed Disease in Peri-urban and Rural Nepal. J Infect Dis. 2018 11 10; 218(suppl_4):S214-S221. PMID: 28961918.
    Citations: 7     Fields:    Translation:HumansCellsPHPublic Health
  44. Sbaih N, Buss B, Goyal D, Rao SR, Benefield R, Walker AT, Esposito DH, Ryan ET, LaRocque RC, Leung DT. Potentially Serious Drug Interactions Resulting From the Pretravel Health Encounter. Open Forum Infect Dis. 2018 Nov; 5(11):ofy266. PMID: 30465013.
    Citations:    
  45. Andrews JR, Qamar FN, Charles RC, Ryan ET. Extensively Drug-Resistant Typhoid - Are Conjugate Vaccines Arriving Just in Time? N Engl J Med. 2018 Oct 18; 379(16):1493-1495. PMID: 30332569.
    Citations: 13     Fields:    Translation:HumansCellsPHPublic Health
  46. Weil AA, Ryan ET. Cholera: recent updates. Curr Opin Infect Dis. 2018 10; 31(5):455-461. PMID: 30048254.
    Citations: 1     Fields:    Translation:HumansCellsPHPublic Health
  47. Khalil IA, Troeger C, Blacker BF, Rao PC, Brown A, Atherly DE, Brewer TG, Engmann CM, Houpt ER, Kang G, Kotloff KL, Levine MM, Luby SP, MacLennan CA, Pan WK, Pavlinac PB, Platts-Mills JA, Qadri F, Riddle MS, Ryan ET, Shoultz DA, Steele AD, Walson JL, Sanders JW, Mokdad AH, Murray CJL, Hay SI, Reiner RC. Morbidity and mortality due to shigella and enterotoxigenic Escherichia coli diarrhoea: the Global Burden of Disease Study 1990-2016. Lancet Infect Dis. 2018 11; 18(11):1229-1240. PMID: 30266330.
    Citations: 29     Fields:    Translation:HumansCells
  48. DiFiori JP, Güllich A, Brenner JS, Côté J, Hainline B, Ryan E, Malina RM. The NBA and Youth Basketball: Recommendations for Promoting a Healthy and Positive Experience. Sports Med. 2018 09; 48(9):2053-2065. PMID: 29961207.
    Citations: 3     Fields:    Translation:Humans
  49. Andrews JR, Baker S, Marks F, Alsan M, Garrett D, Gellin BG, Saha SK, Qamar FN, Yousafzai MT, Bogoch II, Antillon M, Pitzer VE, Kim JH, John J, Gauld J, Mogasale V, Ryan ET, Luby SP, Lo NC. Typhoid conjugate vaccines: a new tool in the fight against antimicrobial resistance. Lancet Infect Dis. 2019 01; 19(1):e26-e30. PMID: 30170987.
    Citations: 7     Fields:    Translation:HumansCellsPHPublic Health
  50. Midani FS, Weil AA, Chowdhury F, Begum YA, Khan AI, Debela MD, Durand HK, Reese AT, Nimmagadda SN, Silverman JD, Ellis CN, Ryan ET, Calderwood SB, Harris JB, Qadri F, David LA, LaRocque RC. Human Gut Microbiota Predicts Susceptibility to Vibrio cholerae Infection. J Infect Dis. 2018 07 13; 218(4):645-653. PMID: 29659916.
    Citations: 5     Fields:    Translation:HumansCells
  51. Domman D, Chowdhury F, Khan AI, Dorman MJ, Mutreja A, Uddin MI, Paul A, Begum YA, Charles RC, Calderwood SB, Bhuiyan TR, Harris JB, LaRocque RC, Ryan ET, Qadri F, Thomson NR. Defining endemic cholera at three levels of spatiotemporal resolution within Bangladesh. Nat Genet. 2018 07; 50(7):951-955. PMID: 29942084.
    Citations: 6     Fields:    Translation:HumansCellsPHPublic Health
  52. Aktar A, Rahman MA, Afrin S, Akter A, Uddin T, Yasmin T, Sami MIN, Dash P, Jahan SR, Chowdhury F, Khan AI, LaRocque RC, Charles RC, Bhuiyan TR, Mandlik A, Kelly M, Kovác P, Xu P, Calderwood SB, Harris JB, Qadri F, Ryan ET. Plasma and memory B cell responses targeting O-specific polysaccharide (OSP) are associated with protection against Vibrio cholerae O1 infection among household contacts of cholera patients in Bangladesh. PLoS Negl Trop Dis. 2018 04; 12(4):e0006399. PMID: 29684006.
    Citations: 7     Fields:    Translation:HumansCells
  53. Islam K, Hossain M, Kelly M, Mayo Smith LM, Charles RC, Bhuiyan TR, Kovác P, Xu P, LaRocque RC, Calderwood SB, Simon JK, Chen WH, Haney D, Lock M, Lyon CE, Kirkpatrick BD, Cohen M, Levine MM, Gurwith M, Harris JB, Qadri F, Ryan ET. Anti-O-specific polysaccharide (OSP) immune responses following vaccination with oral cholera vaccine CVD 103-HgR correlate with protection against cholera after infection with wild-type Vibrio cholerae O1 El Tor Inaba in North American volunteers. PLoS Negl Trop Dis. 2018 04; 12(4):e0006376. PMID: 29624592.
    Citations: 3     Fields:    Translation:HumansCellsPHPublic HealthCTClinical Trials
  54. Sayeed MA, Islam K, Hossain M, Akter NJ, Alam MN, Sultana N, Khanam F, Kelly M, Charles RC, Kovác P, Xu P, Andrews JR, Calderwood SB, Amin J, Ryan ET, Qadri F. Development of a new dipstick (Cholkit) for rapid detection of Vibrio cholerae O1 in acute watery diarrheal stools. PLoS Negl Trop Dis. 2018 03; 12(3):e0006286. PMID: 29538377.
    Citations: 1     Fields:    Translation:HumansCellsPHPublic Health
  55. Siedner MJ, Ryan ET, Bogoch II. Gone or forgotten? The rise and fall of Zika virus. Lancet Public Health. 2018 03; 3(3):e109-e110. PMID: 29519697.
    Citations: 4     Fields:    Translation:HumansCellsPHPublic Health
  56. Iyer AS, Azman AS, Bouhenia M, Deng LO, Anderson CP, Graves M, Kovác P, Xu P, Ryan ET, Harris JB, Sack DA, Luquero FJ, Leung DT. Dried Blood Spots for Measuring Vibrio cholerae-specific Immune Responses. PLoS Negl Trop Dis. 2018 01; 12(1):e0006196. PMID: 29377882.
    Citations: 2     Fields:    Translation:HumansCells
  57. Bourque DL, Bhuiyan TR, Genereux DP, Rashu R, Ellis CN, Chowdhury F, Khan AI, Alam NH, Paul A, Hossain L, Mayo-Smith LM, Charles RC, Weil AA, LaRocque RC, Calderwood SB, Ryan ET, Karlsson EK, Qadri F, Harris JB. Analysis of the Human Mucosal Response to Cholera Reveals Sustained Activation of Innate Immune Signaling Pathways. Infect Immun. 2018 02; 86(2). PMID: 29133347.
    Citations: 4     Fields:    Translation:HumansCells
  58. Leung DT, LaRocque RC, Ryan ET. Travel Medicine. Ann Intern Med. 2018 Jan 02; 168(1):ITC1-ITC16. PMID: 29297035.
    Citations: 1     Fields:    Translation:HumansAnimalsPHPublic Health
  59. Lash RR, Walker AT, Lee CV, LaRocque R, Rao SR, Ryan ET, Brunette G, Holton K, Sotir MJ. Enabling clinicians to easily find location-based travel health recommendations-is innovation needed? J Travel Med. 2018 01 01; 25(1). PMID: 29788401.
    Citations:    Fields:    Translation:Humans
  60. North CM, Allen JG, Okello S, Sentongo R, Kakuhikire B, Ryan ET, Tsai AC, Christiani DC, Siedner MJ. HIV Infection, Pulmonary Tuberculosis, and COPD in Rural Uganda: A Cross-Sectional Study. Lung. 2018 02; 196(1):49-57. PMID: 29260309.
    Citations: 2     Fields:    Translation:Humans
  61. Hagmann SHF, Rao SR, LaRocque RC, Erskine S, Jentes ES, Walker AT, Barnett ED, Chen LH, Hamer DH, Ryan ET. Travel Characteristics and Pretravel Health Care Among Pregnant or Breastfeeding U.S. Women Preparing for International Travel. Obstet Gynecol. 2017 12; 130(6):1357-1365. PMID: 29112671.
    Citations: 3     Fields:    Translation:HumansPHPublic Health
  62. Levade I, Terrat Y, Leducq JB, Weil AA, Mayo-Smith LM, Chowdhury F, Khan AI, Boncy J, Buteau J, Ivers LC, Ryan ET, Charles RC, Calderwood SB, Qadri F, Harris JB, LaRocque RC, Shapiro BJ. Vibrio cholerae genomic diversity within and between patients. Microb Genom. 2017 12; 3(12). PMID: 29306353.
    Citations: 9     Fields:    Translation:HumansCells
  63. Park KS, Kim H, Kim S, Lee K, Park S, Song J, Min C, Khanam F, Rashu R, Bhuiyan TR, Ryan ET, Qadri F, Weissleder R, Cheon J, Charles RC, Lee H. Nanomagnetic System for Rapid Diagnosis of Acute Infection. ACS Nano. 2017 11 28; 11(11):11425-11432. PMID: 29121461.
    Citations: 1     Fields:    Translation:HumansCells
  64. Bhuiyan TR, Hoq MR, Nishat NS, Al Mahbuba D, Rashu R, Islam K, Hossain L, Harris JB, Ryan ET, Calderwood SB, Svennerholm AM, Qadri F. Assessing antigen specific HLA-DR+ antibody secreting cell (DR+ASC) responses in whole blood in enteric infections using an ELISPOT technique. Microbes Infect. 2018 02; 20(2):122-129. PMID: 29104143.
    Citations:    Fields:    Translation:HumansCells
  65. Angelo KM, Kozarsky PE, Ryan ET, Chen LH, Sotir MJ. What proportion of international travellers acquire a travel-related illness? A review of the literature. J Travel Med. 2017 Sep 01; 24(5). PMID: 28931136.
    Citations: 10     Fields:    Translation:Humans
  66. Charles RC, Nakajima R, Liang L, Jasinskas A, Berger A, Leung DT, Kelly M, Xu P, Kovác P, Giffen SR, Harbison JD, Chowdhury F, Khan AI, Calderwood SB, Bhuiyan TR, Harris JB, Felgner PL, Qadri F, Ryan ET. Plasma and Mucosal Immunoglobulin M, Immunoglobulin A, and Immunoglobulin G Responses to the Vibrio cholerae O1 Protein Immunome in Adults With Cholera in Bangladesh. J Infect Dis. 2017 07 01; 216(1):125-134. PMID: 28535267.
    Citations: 4     Fields:    Translation:HumansCells
  67. Hyle EP, Rao SR, Jentes ES, Parker Fiebelkorn A, Hagmann SHF, Taylor Walker A, Walensky RP, Ryan ET, LaRocque RC. Missed Opportunities for Measles, Mumps, Rubella Vaccination Among Departing U.S. Adult Travelers Receiving Pretravel Health Consultations. Ann Intern Med. 2017 07 18; 167(2):77-84. PMID: 28505632.
    Citations: 2     Fields:    Translation:HumansPHPublic Health
  68. Wong KK, Burdette E, Mahon BE, Mintz ED, Ryan ET, Reingold AL. Recommendations of the Advisory Committee on Immunization Practices for Use of Cholera Vaccine. MMWR Morb Mortal Wkly Rep. 2017 May 12; 66(18):482-485. PMID: 28493859.
    Citations: 4     Fields:    Translation:Humans
  69. Xu P, Kelly M, Vann WF, Qadri F, Ryan ET, Kovác P. Conjugate Vaccines from Bacterial Antigens by Squaric Acid Chemistry: A Closer Look. Chembiochem. 2017 04 18; 18(8):799-815. PMID: 28182850.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  70. Lammert S, Walker AT, Erskine S, Rao SR, Esposito DH, Ryan ET, Robbins GK, LaRocque RC. Characteristics of US Travelers to Zika Virus-Affected Countries in the Americas, March 2015-October 2016. Emerg Infect Dis. 2017 02; 23(2):324-327. PMID: 27926355.
    Citations: 3     Fields:    Translation:HumansCells
  71. Hagmann SH, LaRocque RC, Ryan ET. Preparing Pediatric International Travelers for Travelers' Diarrhea: Insights From the Global TravEpiNet. Pediatr Infect Dis J. 2017 02; 36(2):242-243. PMID: 28079839.
    Citations:    Fields:    Translation:Humans
  72. Kauffman RC, Bhuiyan TR, Nakajima R, Mayo-Smith LM, Rashu R, Hoq MR, Chowdhury F, Khan AI, Rahman A, Bhaumik SK, Harris L, O'Neal JT, Trost JF, Alam NH, Jasinskas A, Dotsey E, Kelly M, Charles RC, Xu P, Kovác P, Calderwood SB, Ryan ET, Felgner PL, Qadri F, Wrammert J, Harris JB. Single-Cell Analysis of the Plasmablast Response to Vibrio cholerae Demonstrates Expansion of Cross-Reactive Memory B Cells. mBio. 2016 12 20; 7(6). PMID: 27999163.
    Citations: 17     Fields:    Translation:HumansCells
  73. Uddin MI, Islam S, Nishat NS, Hossain M, Rafique TA, Rashu R, Hoq MR, Zhang Y, Saha A, Harris JB, Calderwood SB, Bhuiyan TR, Ryan ET, Leung DT, Qadri F. Biomarkers of Environmental Enteropathy are Positively Associated with Immune Responses to an Oral Cholera Vaccine in Bangladeshi Children. PLoS Negl Trop Dis. 2016 Nov; 10(11):e0005039. PMID: 27824883.
    Citations: 8     Fields:    Translation:HumansCells
  74. Lammert SM, Rao SR, Jentes ES, Fairley JK, Erskine S, Walker AT, Hagmann SH, Sotir MJ, Ryan ET, LaRocque RC. Refusal of recommended travel-related vaccines among U.S. international travellers in Global TravEpiNet. J Travel Med. 2016 Jul; 24(1). PMID: 27799502.
    Citations: 10     Fields:    Translation:HumansPHPublic Health
  75. Iyer AS, Bouhenia M, Rumunu J, Abubakar A, Gruninger RJ, Pita J, Lino RL, Deng LL, Wamala JF, Ryan ET, Martin S, Legros D, Lessler J, Sack DA, Luquero FJ, Leung DT, Azman AS. Immune Responses to an Oral Cholera Vaccine in Internally Displaced Persons in South Sudan. Sci Rep. 2016 10 24; 6:35742. PMID: 27775046.
    Citations: 8     Fields:    Translation:HumansCellsPHPublic Health
  76. LaRocque RC, Ryan ET. Medical Considerations before International Travel. N Engl J Med. 2016 10 13; 375(15):e32. PMID: 27732815.
    Citations:    Fields:    Translation:Humans
  77. Park KS, Chung HJ, Khanam F, Lee H, Rashu R, Bhuiyan MT, Berger A, Harris JB, Calderwood SB, Ryan ET, Qadri F, Weissleder R, Charles RC. A magneto-DNA nanoparticle system for the rapid and sensitive diagnosis of enteric fever. Sci Rep. 2016 09 08; 6:32878. PMID: 27605393.
    Citations:    Fields:    Translation:HumansCells
  78. LaRocque RL, Ryan ET. Personal Actions to Minimize Mosquito-Borne Illnesses, Including Zika Virus. Ann Intern Med. 2016 10 18; 165(8):589-590. PMID: 27399646.
    Citations: 2     Fields:    Translation:HumansAnimals
  79. Matias WR, Falkard B, Charles RC, Mayo-Smith LM, Teng JE, Xu P, Kovác P, Ryan ET, Qadri F, Franke MF, Ivers LC, Harris JB. Antibody Secreting Cell Responses following Vaccination with Bivalent Oral Cholera Vaccine among Haitian Adults. PLoS Negl Trop Dis. 2016 06; 10(6):e0004753. PMID: 27308825.
    Citations: 4     Fields:    Translation:HumansCellsPHPublic Health
  80. Hatzios SK, Abel S, Martell J, Hubbard T, Sasabe J, Munera D, Clark L, Bachovchin DA, Qadri F, Ryan ET, Davis BM, Weerapana E, Waldor MK. Erratum: Chemoproteomic profiling of host and pathogen enzymes active in cholera. Nat Chem Biol. 2016 05 18; 12(6):466. PMID: 27191648.
    Citations:    Fields:    
  81. Aktar A, Rahman MA, Afrin S, Faruk MO, Uddin T, Akter A, Sami MIN, Yasmin T, Chowdhury F, Khan AI, Leung DT, LaRocque RC, Charles RC, Bhuiyan TR, Mandlik A, Kelly M, Kovác P, Xu P, Calderwood SB, Harris JB, Qadri F, Ryan ET. O-Specific Polysaccharide-Specific Memory B Cell Responses in Young Children, Older Children, and Adults Infected with Vibrio cholerae O1 Ogawa in Bangladesh. Clin Vaccine Immunol. 2016 05; 23(5):427-435. PMID: 27009211.
    Citations: 8     Fields:    Translation:HumansCells
  82. Khan IH, Sayeed MA, Sultana N, Islam K, Amin J, Faruk MO, Khan U, Khanam F, Ryan ET, Qadri F. Development of a Simple, Peripheral-Blood-Based Lateral-Flow Dipstick Assay for Accurate Detection of Patients with Enteric Fever. Clin Vaccine Immunol. 2016 05; 23(5):403-409. PMID: 26961857.
    Citations: 2     Fields:    Translation:HumansCells
  83. Islam K, Sayeed MA, Hossen E, Khanam F, Charles RC, Andrews J, Ryan ET, Qadri F. Comparison of the Performance of the TPTest, Tubex, Typhidot and Widal Immunodiagnostic Assays and Blood Cultures in Detecting Patients with Typhoid Fever in Bangladesh, Including Using a Bayesian Latent Class Modeling Approach. PLoS Negl Trop Dis. 2016 Apr; 10(4):e0004558. PMID: 27058877.
    Citations: 13     Fields:    Translation:Humans
  84. Hatzios SK, Abel S, Martell J, Hubbard T, Sasabe J, Munera D, Clark L, Bachovchin DA, Qadri F, Ryan ET, Davis BM, Weerapana E, Waldor MK. Chemoproteomic profiling of host and pathogen enzymes active in cholera. Nat Chem Biol. 2016 Apr; 12(4):268-274. PMID: 26900865.
    Citations: 15     Fields:    Translation:HumansAnimalsCells
  85. Ryan ET. Troubling news from Asia about treating enteric fever: a coming storm. Lancet Infect Dis. 2016 05; 16(5):508-509. PMID: 26809814.
    Citations: 4     Fields:    Translation:HumansCells
  86. Khan NM, Jentes ES, Brown C, Han P, Rao SR, Kozarsky P, Hagmann SH, LaRocque RC, Ryan ET. Pre-Travel Medical Preparation of Business and Occupational Travelers: An Analysis of the Global TravEpiNet Consortium, 2009 to 2012. J Occup Environ Med. 2016 Jan; 58(1):76-82. PMID: 26479857.
    Citations: 4     Fields:    Translation:Humans
  87. Lammert S, Ryan ET, LaRoque RC. JAMA PATIENT PAGE. Safe and Healthy International Travel. JAMA. 2015 Dec 15; 314(23):2580. PMID: 26670985.
    Citations:    Fields:    Translation:HumansPHPublic Health
  88. Chowdhury F, Mather AE, Begum YA, Asaduzzaman M, Baby N, Sharmin S, Biswas R, Uddin MI, LaRocque RC, Harris JB, Calderwood SB, Ryan ET, Clemens JD, Thomson NR, Qadri F. Vibrio cholerae Serogroup O139: Isolation from Cholera Patients and Asymptomatic Household Family Members in Bangladesh between 2013 and 2014. PLoS Negl Trop Dis. 2015 Nov; 9(11):e0004183. PMID: 26562418.
    Citations: 8     Fields:    Translation:HumansCells
  89. Bhuiyan TR, Hoq MR, Nishat NS, Al Mahbuba D, Rashu R, Islam K, Hossain L, Dey A, Harris JB, Ryan ET, Calderwood SB, Svennerholm AM, Qadri F. Enumeration of Gut-Homing ß7-Positive, Pathogen-Specific Antibody-Secreting Cells in Whole Blood from Enterotoxigenic Escherichia coli- and Vibrio cholerae-Infected Patients, Determined Using an Enzyme-Linked Immunosorbent Spot Assay Technique. Clin Vaccine Immunol. 2016 01; 23(1):27-36. PMID: 26512047.
    Citations: 1     Fields:    Translation:HumansCells
  90. Park KS, Charles RC, Ryan ET, Weissleder R, Lee H. Fluorescence Polarization Based Nucleic Acid Testing for Rapid and Cost-Effective Diagnosis of Infectious Disease. Chemistry. 2015 Nov 09; 21(46):16359-63. PMID: 26420633.
    Citations: 4     Fields:    Translation:Cells
  91. Chowdhury F, Kuchta A, Khan AI, Faruque AS, Calderwood SB, Ryan ET, Qadri F. The increased severity in patients presenting to hospital with diarrhea in Dhaka, Bangladesh since the emergence of the hybrid strain of Vibrio cholerae O1 is not unique to cholera patients. Int J Infect Dis. 2015 Nov; 40:9-14. PMID: 26409202.
    Citations:    Fields:    Translation:HumansCells
  92. Shahunja KM, Leung DT, Ahmed T, Bardhan PK, Ahmed D, Qadri F, Ryan ET, Chisti MJ. Factors Associated with Non-typhoidal Salmonella Bacteremia versus Typhoidal Salmonella Bacteremia in Patients Presenting for Care in an Urban Diarrheal Disease Hospital in Bangladesh. PLoS Negl Trop Dis. 2015; 9(9):e0004066. PMID: 26361076.
    Citations: 8     Fields:    Translation:HumansCells
  93. Schwartz BS, Rosen J, Han PV, Hynes NA, Hagmann SH, Rao SR, Jentes ES, Ryan ET, LaRocque RC. Immunocompromised Travelers: Demographic Characteristics, Travel Destinations, and Pretravel Health Care from the U.S. Global TravEpiNet Consortium. Am J Trop Med Hyg. 2015 Nov; 93(5):1110-1116. PMID: 26304922.
    Citations: 5     Fields:    Translation:HumansPHPublic Health
  94. Khan AI, Chowdhury F, Leung DT, Larocque RC, Harris JB, Ryan ET, Calderwood SB, Qadri F. Cholera in pregnancy: Clinical and immunological aspects. Int J Infect Dis. 2015 Oct; 39:20-4. PMID: 26283553.
    Citations: 3     Fields:    Translation:HumansCells
  95. Sayeed MA, Bufano MK, Xu P, Eckhoff G, Charles RC, Alam MM, Sultana T, Rashu MR, Berger A, Gonzalez-Escobedo G, Mandlik A, Bhuiyan TR, Leung DT, LaRocque RC, Harris JB, Calderwood SB, Qadri F, Vann WF, Kovác P, Ryan ET. A Cholera Conjugate Vaccine Containing O-specific Polysaccharide (OSP) of V. cholerae O1 Inaba and Recombinant Fragment of Tetanus Toxin Heavy Chain (OSP:rTTHc) Induces Serum, Memory and Lamina Proprial Responses against OSP and Is Protective in Mice. PLoS Negl Trop Dis. 2015; 9(7):e0003881. PMID: 26154421.
    Citations: 15     Fields:    Translation:HumansAnimalsCellsPHPublic Health
  96. Leung DT, Das SK, Malek MA, Qadri F, Faruque AS, Chisti MJ, Ryan ET. Concurrent Pneumonia in Children Under 5 Years of Age Presenting to a Diarrheal Hospital in Dhaka, Bangladesh. Am J Trop Med Hyg. 2015 Oct; 93(4):831-5. PMID: 26149863.
    Citations: 6     Fields:    Translation:Humans
  97. Falkard B, Uddin T, Rahman MA, Franke MF, Aktar A, Uddin MI, Bhuiyan TR, Leung DT, Charles RC, Larocque RC, Harris JB, Calderwood SB, Qadri F, Ryan ET. Plasma Leptin Levels in Children Hospitalized with Cholera in Bangladesh. Am J Trop Med Hyg. 2015 Aug; 93(2):244-249. PMID: 26055740.
    Citations: 1     Fields:    Translation:HumansCells
  98. David LA, Weil A, Ryan ET, Calderwood SB, Harris JB, Chowdhury F, Begum Y, Qadri F, LaRocque RC, Turnbaugh PJ. Gut microbial succession follows acute secretory diarrhea in humans. mBio. 2015 May 19; 6(3):e00381-15. PMID: 25991682.
    Citations: 48     Fields:    Translation:HumansCells
  99. Andrews JR, Ryan ET. Diagnostics for invasive Salmonella infections: Current challenges and future directions. Vaccine. 2015 Jun 19; 33 Suppl 3:C8-15. PMID: 25937611.
    Citations: 33     Fields:    Translation:HumansCells
  100. Khanam F, Sayeed MA, Choudhury FK, Sheikh A, Ahmed D, Goswami D, Hossain ML, Brooks A, Calderwood SB, Charles RC, Cravioto A, Ryan ET, Qadri F. Typhoid fever in young children in Bangladesh: clinical findings, antibiotic susceptibility pattern and immune responses. PLoS Negl Trop Dis. 2015 Apr; 9(4):e0003619. PMID: 25849611.
    Citations: 10     Fields:    Translation:HumansCells
  101. Ivers LC, Charles RC, Hilaire IJ, Mayo-Smith LM, Teng JE, Jerome JG, Rychert J, LaRocque RC, Xu P, Kovác? P, Ryan ET, Qadri F, Almazor CP, Franke MF, Harris JB. Immunogenicity of the Bivalent Oral Cholera Vaccine Shanchol in Haitian Adults With HIV Infection. J Infect Dis. 2015 Sep 01; 212(5):779-83. PMID: 25722294.
    Citations: 7     Fields:    Translation:Humans
  102. Ellis CN, LaRocque RC, Uddin T, Krastins B, Mayo-Smith LM, Sarracino D, Karlsson EK, Rahman A, Shirin T, Bhuiyan TR, Chowdhury F, Khan AI, Ryan ET, Calderwood SB, Qadri F, Harris JB. Comparative proteomic analysis reveals activation of mucosal innate immune signaling pathways during cholera. Infect Immun. 2015 Mar; 83(3):1089-103. PMID: 25561705.
    Citations: 19     Fields:    Translation:HumansCells
  103. Sugimoto JD, Koepke AA, Kenah EE, Halloran ME, Chowdhury F, Khan AI, LaRocque RC, Yang Y, Ryan ET, Qadri F, Calderwood SB, Harris JB, Longini IM. Household Transmission of Vibrio cholerae in Bangladesh. PLoS Negl Trop Dis. 2014 Nov; 8(11):e3314. PMID: 25411971.
    Citations: 13     Fields:    Translation:HumansCellsPHPublic Health
  104. Rychert J, Creely D, Mayo-Smith LM, Calderwood SB, Ivers LC, Ryan ET, Boncy J, Qadri F, Ahmed D, Ferraro MJ, Harris JB. Evaluation of matrix-assisted laser desorption ionization-time of flight mass spectrometry for identification of Vibrio cholerae. J Clin Microbiol. 2015 Jan; 53(1):329-31. PMID: 25392355.
    Citations: 1     Fields:    Translation:HumansCells
  105. Keusch GT, Denno DM, Black RE, Duggan C, Guerrant RL, Lavery JV, Nataro JP, Rosenberg IH, Ryan ET, Tarr PI, Ward H, Bhutta ZA, Coovadia H, Lima A, Ramakrishna B, Zaidi AK, Hay Burgess DC, Brewer T. Environmental enteric dysfunction: pathogenesis, diagnosis, and clinical consequences. Clin Infect Dis. 2014 Nov 01; 59 Suppl 4:S207-12. PMID: 25305288.
    Citations: 74     Fields:    Translation:Humans
  106. Kitchens WH, Liu C, Ryan ET, Fernandez-del Castillo C. Hepatic hydatid cyst: a rare cause of recurrent pancreatitis. J Gastrointest Surg. 2014 Nov; 18(11):2057-9. PMID: 25149853.
    Citations: 1     Fields:    Translation:HumansAnimals
  107. Leung DT, Bhuiyan TR, Nishat NS, Hoq MR, Aktar A, Rahman MA, Uddin T, Khan AI, Chowdhury F, Charles RC, Harris JB, Calderwood SB, Qadri F, Ryan ET. Circulating mucosal associated invariant T cells are activated in Vibrio cholerae O1 infection and associated with lipopolysaccharide antibody responses. PLoS Negl Trop Dis. 2014 Aug; 8(8):e3076. PMID: 25144724.
    Citations: 29     Fields:    Translation:HumansCells
  108. Weil AA, Begum Y, Chowdhury F, Khan AI, Leung DT, LaRocque RC, Charles RC, Ryan ET, Calderwood SB, Qadri F, Harris JB. Bacterial shedding in household contacts of cholera patients in Dhaka, Bangladesh. Am J Trop Med Hyg. 2014 Oct; 91(4):738-42. PMID: 25114012.
    Citations: 11     Fields:    Translation:HumansCells
  109. Deshpande BR, Rao SR, Jentes ES, Hills SL, Fischer M, Gershman MD, Brunette GW, Ryan ET, LaRocque RC. Use of Japanese encephalitis vaccine in US travel medicine practices in Global TravEpiNet. Am J Trop Med Hyg. 2014 Oct; 91(4):694-698. PMID: 25070999.
    Citations: 5     Fields:    Translation:HumansCellsPHPublic Health
  110. Gunn JS, Marshall JM, Baker S, Dongol S, Charles RC, Ryan ET. Salmonella chronic carriage: epidemiology, diagnosis, and gallbladder persistence. Trends Microbiol. 2014 Nov; 22(11):648-55. PMID: 25065707.
    Citations: 59     Fields:    Translation:HumansCells