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Leo Am Kim, Ph.D., M.D.

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Mentoring
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Available: 04/05/22, Expires: 06/01/23

Dr. Kim is a clinician-scientist and trained vitreoretinal surgeon, involved in both basic science research and the clinical care of patients. Our work has primarily focused on the role of RUNX1, a transcription factor discovered in our lab to play a role in aberrant angiogenesis and epithelial mesenchymal transition. We work in multiple model systems including the use of patient-derived surgical samples, in vitro cell culture, and genetic mouse models. Our lab has performed transcriptomic analyses of patient-derived tissues, as well as single cell RNA-seq in order to identify new targets for the treatment of sight threatening conditions.


Research
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The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
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  1. R01EY027739 (KIM, LEO A) Aug 5, 2018 - May 31, 2023
    NIH
    Role of Runx1 in Pathologic Ocular Angiogenesis
    Role: Principal Investigator
  2. R21EY027061 (KIM, LEO A) Sep 30, 2016 - Aug 31, 2019
    NIH
    Vasculogenesis in Thyroid Eye Disease
    Role: Principal Investigator

Bibliographic
selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Fitch TC, Frank SI, Li YK, Saint-Geniez M, Kim LA, Shu DY. Real-Time Analysis of Bioenergetics in Primary Human Retinal Pigment Epithelial Cells Using High-Resolution Respirometry. J Vis Exp. 2023 02 03; (192). PMID: 36804905.
    Citations:    Fields:    Translation:HumansCells
  2. Ng PQ, Saint-Geniez M, Kim LA, Shu DY. Divergent Metabolomic Signatures of TGFß2 and TNFa in the Induction of Retinal Epithelial-Mesenchymal Transition. Metabolites. 2023 Jan 31; 13(2). PMID: 36837832; PMCID: PMC9966219.
    Citations:    
  3. Le R, Cui Y, Lu ES, Zhu Y, Garg I, Wang JC, Lu Y, Zeng R, Katz R, Laíns I, Eliott D, Husain D, Kim LA, Miller JB. Prevalence of venous loops and association with retinal ischemia in diabetic retinopathy using widefield swept-source OCT angiography. Graefes Arch Clin Exp Ophthalmol. 2023 Jan 30. PMID: 36715770.
    Citations:    Fields:    
  4. Wu F, Kim LA. Outcomes of Rhegmatogenous Retinal Detachment Repair Following Infectious Endophthalmitis. Retina. 2022 Dec 14. PMID: 36729639.
    Citations:    Fields:    
  5. Zeng R, Vingopoulos F, Wang M, Bannerman A, Wescott HE, Baldwin G, Katz R, Koch T, Elze T, Kim LA, Vavvas DG, Husain D, Miller JB. Structure-function association between contrast sensitivity and retinal thickness (total, regional, and individual retinal layer) in patients with idiopathic epiretinal membrane. Graefes Arch Clin Exp Ophthalmol. 2023 Mar; 261(3):631-639. PMID: 36149494.
    Citations:    Fields:    
  6. Wai KM, Begaj T, Patil S, Chen EM, Miller JB, Kylstra J, Aronow ME, Young LH, Huckfeldt R, Husain D, Kim LA, Vavvas DG, Eliott D, Mukai S, Gragoudas ES, Patel NA, Sobrin L, Miller JW, Parikh R, Wu DM. The Effect of Sample Medication Use on Subsequent Anti-VEGF Agent Selection for Neovascular Age-Related Macular Degeneration. Semin Ophthalmol. 2022 Oct-Nov; 37(7-8):902-908. PMID: 35923110.
    Citations:    Fields:    
  7. Li CY, Garg I, Bannai D, Kasetty M, Katz R, Adhan I, Douglas KAA, Wang JC, Kim LA, Keshavan M, Lizano P, Miller JB. Sex-Specific Changes in Choroid Vasculature Among Patients with Schizophrenia and Bipolar Disorder. Clin Ophthalmol. 2022; 16:2363-2371. PMID: 35924185; PMCID: PMC9343178.
    Citations:    
  8. Shu DY, Frank SI, Fitch TC, Karg MM, Butcher ER, Nnuji-John E, Kim LA, Saint-Geniez M. Dimethyl Fumarate Blocks Tumor Necrosis Factor-Alpha-Driven Inflammation and Metabolic Rewiring in the Retinal Pigment Epithelium. Front Mol Neurosci. 2022; 15:896786. PMID: 35813071; PMCID: PMC9259930.
    Citations:    
  9. Delgado-Tirado S, Gonzalez-Buendia L, An M, Amarnani D, Isaacs-Bernal D, Whitmore H, Arevalo-Alquichire S, Leyton-Cifuentes D, Ruiz-Moreno JM, Arboleda-Velasquez JF, Kim LA. Topical Nanoemulsion of a Runt-related Transcription Factor 1 Inhibitor for the Treatment of Pathologic Ocular Angiogenesis. Ophthalmol Sci. 2022 Sep; 2(3). PMID: 36213726; PMCID: PMC9536424.
    Citations:    
  10. Rudnick ND, Kim LA, Comander J. Adeno-associated Viral Vectors in the Retina: Delivering Gene Therapy to the Right Destination. Int Ophthalmol Clin. 2022 Apr 01; 62(2):215-229. PMID: 35325920.
    Citations:    Fields:    Translation:Humans
  11. Garg I, Uwakwe C, Le R, Lu ES, Cui Y, Wai KM, Katz R, Zhu Y, Moon JY, Li CY, Laíns I, Eliott D, Elze T, Kim LA, Wu DM, Miller JW, Husain D, Vavvas DG, Miller JB. Nonperfusion Area and Other Vascular Metrics by Wider Field Swept-Source OCT Angiography as Biomarkers of Diabetic Retinopathy Severity. Ophthalmol Sci. 2022 Jun; 2(2). PMID: 35647573; PMCID: PMC9137369.
    Citations:    
  12. Vingopoulos F, Garg I, Kim EL, Thomas M, Silverman RF, Kasetty M, Hassan ZY, Yu G, Joltikov K, Choi EY, Laíns I, Kim LA, Zacks DN, Miller JB. Quantitative contrast sensitivity test to assess visual function in central serous chorioretinopathy. Br J Ophthalmol. 2022 Mar 15. PMID: 35292427.
    Citations:    Fields:    
  13. Wai KM, Rossin EJ, Delgado-Tirado S, Cadorette JJ, Boody RP, Rodriguez M, Kim LA. Hypopyon and White Cataract Due to an Intraocular Helminth. Ophthalmic Surg Lasers Imaging Retina. 2022 03; 53(3):168-171. PMID: 35272562.
    Citations:    Fields:    Translation:HumansAnimals
  14. Bannai D, Adhan I, Katz R, Kim LA, Keshavan M, Miller JB, Lizano P. Quantifying Retinal Microvascular Morphology in Schizophrenia Using Swept-Source Optical Coherence Tomography Angiography. Schizophr Bull. 2022 01 21; 48(1):80-89. PMID: 34554256; PMCID: PMC8781445.
    Citations: 2     Fields:    Translation:Humans
  15. Ehlers JP, Yeh S, Maguire MG, Smith JR, Mruthyunjaya P, Jain N, Kim LA, Weng CY, Flaxel CJ, Schoenberger SD, Kim SJ. Intravitreal Pharmacotherapies for Diabetic Macular Edema: A Report by the American Academy of Ophthalmology. Ophthalmology. 2022 01; 129(1):88-99. PMID: 34446301.
    Citations: 3     Fields:    Translation:Humans
  16. Moon JY, Garg I, Cui Y, Katz R, Zhu Y, Le R, Lu Y, Lu ES, Ludwig CA, Elze T, Wu DM, Eliott D, Miller JW, Kim LA, Husain D, Vavvas DG, Miller JB. Wide-field swept-source optical coherence tomography angiography in the assessment of retinal microvasculature and choroidal thickness in patients with myopia. Br J Ophthalmol. 2023 01; 107(1):102-108. PMID: 34385166.
    Citations: 4     Fields:    
  17. Vingopoulos F, Wai KM, Katz R, Vavvas DG, Kim LA, Miller JB. Measuring the Contrast Sensitivity Function in Non-Neovascular and Neovascular Age-Related Macular Degeneration: The Quantitative Contrast Sensitivity Function Test. J Clin Med. 2021 Jun 24; 10(13). PMID: 34202569.
    Citations: 1     
  18. Whitmore HAB, Kim LA. Understanding the Role of Blood Vessels in the Neurologic Manifestations of Coronavirus Disease 2019 (COVID-19). Am J Pathol. 2021 11; 191(11):1946-1954. PMID: 34126084; PMCID: PMC8193973.
    Citations: 2     Fields:    Translation:HumansCells
  19. O'Hare M, Amarnani D, Whitmore HAB, An M, Marino C, Ramos L, Delgado-Tirado S, Hu X, Chmielewska N, Chandrahas A, Fitzek A, Heinrich F, Steurer S, Ondruschka B, Glatzel M, Krasemann S, Sepulveda-Falla D, Lagares D, Pedron J, Bushweller JH, Liu P, Arboleda-Velasquez JF, Kim LA. Targeting Runt-Related Transcription Factor 1 Prevents Pulmonary Fibrosis and Reduces Expression of Severe Acute Respiratory Syndrome Coronavirus 2 Host Mediators. Am J Pathol. 2021 07; 191(7):1193-1208. PMID: 33894177; PMCID: PMC8059259.
    Citations: 5     Fields:    Translation:AnimalsCells
  20. Cui Y, Zhu Y, Lu ES, Le R, Laíns I, Katz R, Wang JC, Garg I, Lu Y, Zeng R, Eliott D, Vavvas DG, Husain D, Miller JW, Kim LA, Wu DM, Miller JB. Widefield Swept-Source OCT Angiography Metrics Associated with the Development of Diabetic Vitreous Hemorrhage: A Prospective Study. Ophthalmology. 2021 09; 128(9):1312-1324. PMID: 33647282; PMCID: PMC9055532.
    Citations: 1     Fields:    Translation:Humans
  21. Rossin EJ, Sobrin L, Kim LA. Single-cell RNA sequencing: An overview for the ophthalmologist. Semin Ophthalmol. 2021 May 19; 36(4):191-197. PMID: 33635751; PMCID: PMC9040911.
    Citations:    Fields:    Translation:Humans
  22. Wai KM, Vingopoulos F, Garg I, Kasetty M, Silverman RF, Katz R, Laíns I, Miller JW, Husain D, Vavvas DG, Kim LA, Miller JB. Contrast sensitivity function in patients with macular disease and good visual acuity. Br J Ophthalmol. 2022 06; 106(6):839-844. PMID: 33536229.
    Citations: 3     Fields:    Translation:Humans
  23. Armstrong GW, Kim LA, Vingopoulos F, Park JY, Garg I, Kasetty M, Silverman RF, Zeng R, Douglas VP, Lopera F, Baena A, Giraldo M, Norton D, Cronin-Golomb A, Arboleda-Velasquez JF, Quiroz YT, Miller JB. Retinal Imaging Findings in Carriers With PSEN1-Associated Early-Onset Familial Alzheimer Disease Before Onset of Cognitive Symptoms. JAMA Ophthalmol. 2021 01 01; 139(1):49-56. PMID: 33180114; PMCID: PMC7662482.
    Citations: 2     Fields:    Translation:Humans
  24. Lu ES, Cui Y, Le R, Zhu Y, Wang JC, Laíns I, Katz R, Lu Y, Zeng R, Garg I, Wu DM, Eliott D, Vavvas DG, Husain D, Miller JW, Kim LA, Miller JB. Detection of neovascularisation in the vitreoretinal interface slab using widefield swept-source optical coherence tomography angiography in diabetic retinopathy. Br J Ophthalmol. 2022 04; 106(4):534-539. PMID: 33355148; PMCID: PMC9092312.
    Citations: 6     Fields:    Translation:Humans
  25. Gonzalez-Buendia L, Delgado-Tirado S, An M, O'Hare M, Amarnani D, A B Whitmore H, Zhao G, Ruiz-Moreno JM, Arboleda-Velasquez JF, Kim LA. Treatment of Experimental Choroidal Neovascularization via RUNX1 Inhibition. Am J Pathol. 2021 03; 191(3):418-424. PMID: 33345998; PMCID: PMC7931615.
    Citations: 1     Fields:    Translation:Animals
  26. Delgado-Tirado S, Amarnani D, Zhao G, Rossin EJ, Eliott D, Miller JB, Greene WA, Ramos L, Arevalo-Alquichire S, Leyton-Cifuentes D, Gonzalez-Buendia L, Isaacs-Bernal D, Whitmore HAB, Chmielewska N, Duffy BV, Kim E, Wang HC, Ruiz-Moreno JM, Kim LA, Arboleda-Velasquez JF. Topical delivery of a small molecule RUNX1 transcription factor inhibitor for the treatment of proliferative vitreoretinopathy. Sci Rep. 2020 11 30; 10(1):20554. PMID: 33257736.
    Citations: 2     Fields:    Translation:HumansAnimals
  27. Vingopoulos F, Wang Y, Grob S, Li CYL, Eliott D, Kim LA, Vavvas DG, Miller JB. Open Globe Injury with Intraocular Foreign Body. J Vitreoretin Dis. 2021 Jul 01; 5(4):288-294. PMID: 34386688; PMCID: PMC8356917.
    Citations: 3     
  28. Thomas M, Silverman RF, Vingopoulos F, Kasetty M, Yu G, Kim EL, Omari AA, Joltikov KA, Choi EY, Kim LA, Zacks DN, Miller JB. Active Learning of Contrast Sensitivity to Assess Visual Function in Macula-off Retinal Detachment. J Vitreoretin Dis. 2021 Jul 01; 5(4):313-320. PMID: 34458662; PMCID: PMC8387972.
    Citations: 1     
  29. Whitmore HAB, Amarnani D, O'Hare M, Delgado-Tirado S, Gonzalez-Buendia L, An M, Pedron J, Bushweller JH, Arboleda-Velasquez JF, Kim LA. TNF-a signaling regulates RUNX1 function in endothelial cells. FASEB J. 2021 02; 35(2):e21155. PMID: 33135824; PMCID: PMC7821222.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  30. Parikh D, Eliott D, Kim LA. Fibroblast Growth Factor Receptor Inhibitor-Associated Retinopathy. JAMA Ophthalmol. 2020 10 01; 138(10):1101-1103. PMID: 32789485.
    Citations: 4     Fields:    Translation:Humans
  31. Lu Y, Wang JC, Cui Y, Zhu Y, Zeng R, Lu ES, Katz R, Husain D, Vavvas DG, Kim LA, Miller JW, Miller JB. A quantitative comparison of four optical coherence tomography angiography devices in healthy eyes. Graefes Arch Clin Exp Ophthalmol. 2021 Jun; 259(6):1493-1501. PMID: 32975683.
    Citations:    Fields:    Translation:Humans
  32. Begaj T, Marmalidou A, Papakostas TD, Diaz JD, Kim LA, Wu DM, Miller JB. Outcomes of primary rhegmatogenous retinal detachment repair with extensive scleral-depressed vitreous removal and dynamic examination. PLoS One. 2020; 15(9):e0239138. PMID: 32970724.
    Citations: 1     Fields:    Translation:Humans
  33. Amarnani D, Sanchez AV, Wong LL, Duffy BV, Ramos L, Freitag SK, Bielenberg DR, Kim LA, Lee NG. Characterization of a Murine Model of Oxazolone-Induced Orbital Inflammation. Transl Vis Sci Technol. 2020 07; 9(8):26. PMID: 32855872.
    Citations: 1     Fields:    Translation:HumansAnimals
  34. Silverman RF, Kasetty M, Vingopoulos F, Katz R, Cho J, Lesmes LA, Zacks DN, Kim LA, Miller JB. Measuring Contrast Sensitivity Function With Active Learning in Retinal Vein Occlusion: A New Endpoint of Visual Function. Ophthalmic Surg Lasers Imaging Retina. 2020 07 01; 51(7):392-400. PMID: 32706897.
    Citations: 3     Fields:    Translation:Humans
  35. McKay KM, Vingopoulos F, Wang JC, Papakostas TD, Silverman RF, Marmalidou A, Lains I, Eliott D, Vavvas DG, Kim LA, Wu DM, Miller JB. Retinal Microvasculature Changes After Repair of Macula-off Retinal Detachment Assessed with Optical Coherence Tomography Angiography. Clin Ophthalmol. 2020; 14:1759-1767. PMID: 32616995; PMCID: PMC7326212.
    Citations: 7     
  36. Cui Y, Zhu Y, Wang JC, Lu Y, Zeng R, Katz R, Vingopoulos F, Le R, Laíns I, Wu DM, Eliott D, Vavvas DG, Husain D, Miller JW, Kim LA, Miller JB. Comparison of widefield swept-source optical coherence tomography angiography with ultra-widefield colour fundus photography and fluorescein angiography for detection of lesions in diabetic retinopathy. Br J Ophthalmol. 2021 04; 105(4):577-581. PMID: 32591347; PMCID: PMC9092310.
    Citations: 14     Fields:    Translation:Humans
  37. Zhu Y, Cui Y, Wang JC, Lu Y, Zeng R, Katz R, Wu DM, Eliott D, Vavvas DG, Husain D, Miller JW, Kim LA, Miller JB. Different Scan Protocols Affect the Detection Rates of Diabetic Retinopathy Lesions by Wide-Field Swept-Source Optical Coherence Tomography Angiography. Am J Ophthalmol. 2020 07; 215:72-80. PMID: 32205122.
    Citations: 6     Fields:    Translation:Humans
  38. Bannai D, Lizano P, Kasetty M, Lutz O, Zeng V, Sarvode S, Kim LA, Hill S, Tamminga C, Clementz B, Gershon E, Pearlson G, Miller JB, Keshavan M. Retinal layer abnormalities and their association with clinical and brain measures in psychotic disorders: A preliminary study. Psychiatry Res Neuroimaging. 2020 05 30; 299:111061. PMID: 32145500.
    Citations: 6     Fields:    Translation:HumansCells
  39. Yonekawa Y, Modi YS, Kim LA, Skondra D, Kim JE, Wykoff CC. American Society of Retina Specialists Clinical Practice Guidelines on the Management of Nonproliferative and Proliferative Diabetic Retinopathy without Diabetic Macular Edema. J Vitreoretin Dis. 2020 Mar 01; 4(2):125-135. PMID: 34308094; PMCID: PMC8297841.
    Citations:    
  40. Lizano P, Bannai D, Lutz O, Kim LA, Miller J, Keshavan M. A Meta-analysis of Retinal Cytoarchitectural Abnormalities in Schizophrenia and Bipolar Disorder. Schizophr Bull. 2020 01 04; 46(1):43-53. PMID: 31112601.
    Citations: 16     Fields:    Translation:Humans
  41. Tieger MG, Moussa K, Kim LA, Eliott D. The History of Visualization in Vitrectomy Surgery. Int Ophthalmol Clin. 2020; 60(1):1-15. PMID: 31855891.
    Citations:    Fields:    Translation:Humans
  42. Cui Y, Zhu Y, Wang JC, Lu Y, Zeng R, Katz R, Wu DM, Vavvas DG, Husain D, Miller JW, Kim LA, Miller JB. Imaging Artifacts and Segmentation Errors With Wide-Field Swept-Source Optical Coherence Tomography Angiography in Diabetic Retinopathy. Transl Vis Sci Technol. 2019 Nov; 8(6):18. PMID: 31772829; PMCID: PMC6859832.
    Citations: 13     Fields:    
  43. Arboleda-Velasquez JF, Lopera F, O'Hare M, Delgado-Tirado S, Marino C, Chmielewska N, Saez-Torres KL, Amarnani D, Schultz AP, Sperling RA, Leyton-Cifuentes D, Chen K, Baena A, Aguillon D, Rios-Romenets S, Giraldo M, Guzmán-Vélez E, Norton DJ, Pardilla-Delgado E, Artola A, Sanchez JS, Acosta-Uribe J, Lalli M, Kosik KS, Huentelman MJ, Zetterberg H, Blennow K, Reiman RA, Luo J, Chen Y, Thiyyagura P, Su Y, Jun GR, Naymik M, Gai X, Bootwalla M, Ji J, Shen L, Miller JB, Kim LA, Tariot PN, Johnson KA, Reiman EM, Quiroz YT. Resistance to autosomal dominant Alzheimer's disease in an APOE3 Christchurch homozygote: a case report. Nat Med. 2019 11; 25(11):1680-1683. PMID: 31686034.
    Citations: 117     Fields:    Translation:Humans
  44. McHugh KJ, Li D, Wang JC, Kwark L, Loo J, Macha V, Farsiu S, Kim LA, Saint-Geniez M. Computational modeling of retinal hypoxia and photoreceptor degeneration in patients with age-related macular degeneration. PLoS One. 2019; 14(6):e0216215. PMID: 31185022; PMCID: PMC6559637.
    Citations: 9     Fields:    Translation:Humans
  45. Lee Kim E, Weiner AJ, Ung C, Roh M, Wang J, Lee IJ, Huang NT, Stem M, Dahrouj M, Eliott D, Vavvas DG, Young LHY, Williams GA, Garretson BR, Kim IK, Hassan TS, Mukai S, Ruby AJ, Faia LJ, Capone A, Comander J, Kim LA, Wu DM, Drenser KA, Woodward MA, Wolfe JD, Yonekawa Y. Characterization of Epiretinal Proliferation in Full-Thickness Macular Holes and Effects on Surgical Outcomes. Ophthalmol Retina. 2019 08; 3(8):694-702. PMID: 31104985; PMCID: PMC6684822.
    Citations: 3     Fields:    Translation:Humans
  46. Liu Y, Rajamanickam VP, Parikh RS, Loomis SJ, Kloek CE, Kim LA, Hitchmoth DL, Song BJ, Xerras DC, Pasquale LR. Diabetic Retinopathy Assessment Variability Among Eye Care Providers in an Urban Teleophthalmology Program. Telemed J E Health. 2019 04; 25(4):301-308. PMID: 30040526; PMCID: PMC6482899.
    Citations: 5     Fields:    Translation:Humans
  47. Quiroz YT, Sperling RA, Norton DJ, Baena A, Arboleda-Velasquez JF, Cosio D, Schultz A, Lapoint M, Guzman-Velez E, Miller JB, Kim LA, Chen K, Tariot PN, Lopera F, Reiman EM, Johnson KA. Association Between Amyloid and Tau Accumulation in Young Adults With Autosomal Dominant Alzheimer Disease. JAMA Neurol. 2018 05 01; 75(5):548-556. PMID: 29435558; PMCID: PMC5885174.
    Citations: 75     Fields:    Translation:Humans
  48. Carvalho LS, Xiao R, Wassmer SJ, Langsdorf A, Zinn E, Pacouret S, Shah S, Comander JI, Kim LA, Lim L, Vandenberghe LH. Synthetic Adeno-Associated Viral Vector Efficiently Targets Mouse and Nonhuman Primate Retina In Vivo. Hum Gene Ther. 2018 07; 29(7):771-784. PMID: 29325457; PMCID: PMC6066192.
    Citations: 19     Fields:    Translation:HumansAnimalsCells
  49. Kim LA, Eliott D. Management of Submacular Hemorrhage in Age-Related Macular Degeneration. Ophthalmol Retina. 2018 03; 2(3):177-179. PMID: 31047580.
    Citations:    Fields:    Translation:Humans
  50. Heiferman MJ, Rahmani S, Jampol LM, Nesper PL, Skondra D, Kim LA, Fawzi AA. ACUTE POSTERIOR MULTIFOCAL PLACOID PIGMENT EPITHELIOPATHY ON OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY. Retina. 2017 Nov; 37(11):2084-2094. PMID: 28151840; PMCID: PMC5538964.
    Citations: 13     Fields:    Translation:Humans
  51. Amarnani D, Machuca-Parra AI, Wong LL, Marko CK, Stefater JA, Stryjewski TP, Eliott D, Arboleda-Velasquez JF, Kim LA. Effect of Methotrexate on an In Vitro Patient-Derived Model of Proliferative Vitreoretinopathy. Invest Ophthalmol Vis Sci. 2017 08 01; 58(10):3940-3949. PMID: 28777835; PMCID: PMC5544356.
    Citations: 12     Fields:    Translation:Humans
  52. Machuca-Parra AI, Bigger-Allen AA, Sanchez AV, Boutabla A, Cardona-Vélez J, Amarnani D, Saint-Geniez M, Siebel CW, Kim LA, D'Amore PA, Arboleda-Velasquez JF. Therapeutic antibody targeting of Notch3 signaling prevents mural cell loss in CADASIL. J Exp Med. 2017 Aug 07; 214(8):2271-2282. PMID: 28698285; PMCID: PMC5551569.
    Citations: 18     Fields:    Translation:AnimalsCells
  53. Ung C, Sanchez AV, Shen L, Davoudi S, Ahmadi T, Navarro-Gomez D, Chen CJ, Hancock H, Penman A, Hoadley S, Consugar M, Restrepo C, Shah VA, Arboleda-Velasquez JF, Sobrin L, Gai X, Kim LA. Whole exome sequencing identification of novel candidate genes in patients with proliferative diabetic retinopathy. Vision Res. 2017 10; 139:168-176. PMID: 28431867; PMCID: PMC5912887.
    Citations: 13     Fields:    Translation:Humans
  54. Lam JD, Oh DJ, Wong LL, Amarnani D, Park-Windhol C, Sanchez AV, Cardona-Velez J, McGuone D, Stemmer-Rachamimov AO, Eliott D, Bielenberg DR, van Zyl T, Shen L, Gai X, D'Amore PA, Kim LA, Arboleda-Velasquez JF. Identification of RUNX1 as a Mediator of Aberrant Retinal Angiogenesis. Diabetes. 2017 07; 66(7):1950-1956. PMID: 28400392; PMCID: PMC5482092.
    Citations: 22     Fields:    Translation:HumansAnimalsCells
  55. Yonekawa Y, Qian CX, Patel AV, Kim LA, Eliott D. Occult Perforating Globe Injury Caused by Intraocular Foreign Body. Ophthalmic Surg Lasers Imaging Retina. 2016 12 01; 47(12):1162-1163. PMID: 27977843.
    Citations:    Fields:    Translation:Humans
  56. Stefater JA, Eliott D, Kim LA. Drainage and analysis of suprachoroidal fluid in a patient with acute systemic lupus erythematous. Am J Ophthalmol Case Rep. 2017 Apr; 5:29-32. PMID: 29503942; PMCID: PMC5758017.
    Citations: 3     
  57. Papakostas TD, Jakobiec FA, Stagner AM, Eliott D, Kim LA. Small-Caliber Retinal Vasculitis Associated With Giant Cell Arteritis: A New Finding. Ophthalmic Surg Lasers Imaging Retina. 2016 11 01; 47(11):1054-1056. PMID: 27842201.
    Citations: 2     Fields:    Translation:Humans
  58. Finn AP, Eliott D, Kim LA, Husain D, Wu DM, Young LH, Kim IK, Andreoli C, Skondra D, Vavvas DG, Miller JB. Characteristics and Outcomes of Simultaneous Bilateral Rhegmatogenous Retinal Detachments. Ophthalmic Surg Lasers Imaging Retina. 2016 09 01; 47(9):840-5. PMID: 27631480.
    Citations: 2     Fields:    Translation:Humans
  59. Pennock S, Kim LA, Kazlauskas A. Vascular Endothelial Cell Growth Factor A Acts via Platelet-Derived Growth Factor Receptor a To Promote Viability of Cells Enduring Hypoxia. Mol Cell Biol. 2016 09 15; 36(18):2314-27. PMID: 27325673; PMCID: PMC5007796.
    Citations: 6     Fields:    Translation:AnimalsCells
  60. Wong LL, Lee NG, Amarnani D, Choi CJ, Bielenberg DR, Freitag SK, D'Amore PA, Kim LA. Orbital Angiogenesis and Lymphangiogenesis in Thyroid Eye Disease: An Analysis of Vascular Growth Factors with Clinical Correlation. Ophthalmology. 2016 09; 123(9):2028-36. PMID: 27423310.
    Citations: 9     Fields:    Translation:Humans
  61. Miller JB, Yonekawa Y, Eliott D, Kim IK, Kim LA, Loewenstein JI, Sobrin L, Young LH, Mukai S, Vavvas DG. Long-term Follow-up and Outcomes in Traumatic Macular Holes. Am J Ophthalmol. 2016 06; 166:206-207. PMID: 27084591.
    Citations: 2     Fields:    Translation:Humans
  62. Miller JB, Yonekawa Y, Eliott D, Kim IK, Kim LA, Loewenstein JI, Sobrin L, Young LH, Mukai S, Vavvas DG. Long-term Follow-up and Outcomes in Traumatic Macular Holes. Am J Ophthalmol. 2015 Dec; 160(6):1255-1258.e1. PMID: 26393438.
    Citations: 15     Fields:    Translation:Humans
  63. Lim LS, Ng WY, Mathur R, Wong D, Wong EY, Yeo I, Cheung CM, Lee SY, Wong TY, Papakostas TD, Kim LA. Conversion to aflibercept for diabetic macular edema unresponsive to ranibizumab or bevacizumab. Clin Ophthalmol. 2015; 9:1715-8. PMID: 26396494; PMCID: PMC4577250.
    Citations: 21     
  64. Sweigard JH, Matsumoto H, Smith KE, Kim LA, Paschalis EI, Okonuki Y, Castillejos A, Kataoka K, Hasegawa E, Yanai R, Husain D, Lambris JD, Vavvas D, Miller JW, Connor KM. Inhibition of the alternative complement pathway preserves photoreceptors after retinal injury. Sci Transl Med. 2015 Jul 22; 7(297):297ra116. PMID: 26203084.
    Citations: 17     Fields:    Translation:HumansAnimalsCells
  65. Kim LA, Wong LL, Amarnani DS, Bigger-Allen AA, Hu Y, Marko CK, Eliott D, Shah VA, McGuone D, Stemmer-Rachamimov AO, Gai X, D'Amore PA, Arboleda-Velasquez JF. Characterization of cells from patient-derived fibrovascular membranes in proliferative diabetic retinopathy. Mol Vis. 2015; 21:673-87. PMID: 26120272; PMCID: PMC4462955.
    Citations: 8     Fields:    Translation:HumansCells
  66. Srinivasan PP, Kim LA, Mettu PS, Cousins SW, Comer GM, Izatt JA, Farsiu S. Fully automated detection of diabetic macular edema and dry age-related macular degeneration from optical coherence tomography images. Biomed Opt Express. 2014 Oct 01; 5(10):3568-77. PMID: 25360373; PMCID: PMC4206325.
    Citations: 55     
  67. Valdez CN, Arboleda-Velasquez JF, Amarnani DS, Kim LA, D'Amore PA. Retinal microangiopathy in a mouse model of inducible mural cell loss. Am J Pathol. 2014 Oct; 184(10):2618-26. PMID: 25092275; PMCID: PMC4715212.
    Citations: 15     Fields:    Translation:HumansAnimalsCells
  68. Kim LA, Amarnani D, Gnanaguru G, Tseng WA, Vavvas DG, D'Amore PA. Tamoxifen toxicity in cultured retinal pigment epithelial cells is mediated by concurrent regulated cell death mechanisms. Invest Ophthalmol Vis Sci. 2014 Jul 03; 55(8):4747-58. PMID: 24994868.
    Citations: 21     Fields:    Translation:HumansCells
  69. Miller JB, Kim LA, Wu DM, Vavvas DG, Eliott D, Husain D. Ocriplasmin for treatment of stage 2 macular holes: early clinical results. Ophthalmic Surg Lasers Imaging Retina. 2014 Jul-Aug; 45(4):293-7. PMID: 25037011.
    Citations: 7     Fields:    Translation:Humans
  70. Lee NG, Kim LA, Freitag SK. The role of genetics in the pathogenesis of periocular cutaneous neoplasms: implications for targeted therapy. Semin Ophthalmol. 2013 Sep-Nov; 28(5-6):267-74. PMID: 24138034.
    Citations: 1     Fields:    Translation:Humans
  71. Bagchi M, Kim LA, Boucher J, Walshe TE, Kahn CR, D'Amore PA. Vascular endothelial growth factor is important for brown adipose tissue development and maintenance. FASEB J. 2013 Aug; 27(8):3257-71. PMID: 23682123.
    Citations: 40     Fields:    Translation:AnimalsCells
  72. Kim LH, Zhang M, Howell RW, Yue NJ, Khan AJ. Technical note: contrast solution density and cross section errors in inhomogeneity-corrected dose calculation for breast balloon brachytherapy. Med Phys. 2013 Jan; 40(1):011703. PMID: 23298073.
    Citations:    Fields:    Translation:Humans
  73. Sohn EH, He S, Kim LA, Salehi-Had H, Javaheri M, Spee C, Dustin L, Hinton DR, Eliott D. Angiofibrotic response to vascular endothelial growth factor inhibition in diabetic retinal detachment: report no. 1. Arch Ophthalmol. 2012 Sep; 130(9):1127-34. PMID: 22965588; PMCID: PMC3984910.
    Citations: 18     Fields:    Translation:Humans
  74. Huang AS, Kim LA, Fawzi AA. Clinical characteristics of a large choroideremia pedigree carrying a novel CHM mutation. Arch Ophthalmol. 2012 Sep; 130(9):1184-9. PMID: 22965595; PMCID: PMC3984921.
    Citations: 17     Fields:    Translation:Humans
  75. Kim LA, D'Amore PA. A brief history of anti-VEGF for the treatment of ocular angiogenesis. Am J Pathol. 2012 Aug; 181(2):376-9. PMID: 22749677; PMCID: PMC5691342.
    Citations: 57     Fields:    Translation:HumansAnimals
  76. Kim LH, Goyal S, Haffty BG, Taunk NK, Yue NJ. Using respiratory motion to guide planning target volume margins for external beam partial breast irradiation. Int J Radiat Oncol Biol Phys. 2012 Mar 15; 82(4):1303-6. PMID: 22385703.
    Citations: 3     Fields:    Translation:Humans
  77. Ghilezan M, Martinez A, Gustason G, Krauss D, Antonucci JV, Chen P, Fontanesi J, Wallace M, Ye H, Casey A, Sebastian E, Kim L, Limbacher A. High-dose-rate brachytherapy as monotherapy delivered in two fractions within one day for favorable/intermediate-risk prostate cancer: preliminary toxicity data. Int J Radiat Oncol Biol Phys. 2012 Jul 01; 83(3):927-32. PMID: 22197086.
    Citations: 20     Fields:    Translation:Humans
  78. Thomas BB, Shi D, Khine K, Kim LA, Sadda SR. Modulatory influence of stimulus parameters on optokinetic head-tracking response. Neurosci Lett. 2010 Jul 26; 479(2):92-6. PMID: 20488227.
    Citations: 11     Fields:    Translation:HumansAnimals
  79. Kim LA, Khurana RN, Parikh JG, Rao NA. Melanin-laden macrophages in the CSF to diagnose Vogt-Koyanagi-Harada simulating ocular syphilis. Ocul Immunol Inflamm. 2008 Jan-Feb; 16(1):59-61. PMID: 18379946.
    Citations: 3     Fields:    Translation:HumansCells
  80. Kim LA, Furst J, Gutierrez D, Butler MH, Xu S, Goldstein SA, Grigorieff N. Three-dimensional structure of I(to); Kv4.2-KChIP2 ion channels by electron microscopy at 21 Angstrom resolution. Neuron. 2004 Feb 19; 41(4):513-9. PMID: 14980201.
    Citations: 40     Fields:    Translation:HumansAnimalsCells
  81. Kim LA, Furst J, Butler MH, Xu S, Grigorieff N, Goldstein SA. Ito channels are octomeric complexes with four subunits of each Kv4.2 and K+ channel-interacting protein 2. J Biol Chem. 2004 Feb 13; 279(7):5549-54. PMID: 14623880.
    Citations: 29     Fields:    Translation:HumansAnimalsCells
  82. Chen H, Kim LA, Rajan S, Xu S, Goldstein SA. Charybdotoxin binding in the I(Ks) pore demonstrates two MinK subunits in each channel complex. Neuron. 2003 Sep 25; 40(1):15-23. PMID: 14527430.
    Citations: 69     Fields:    Translation:HumansAnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.