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Irving Hyman Goldberg, Ph.D., M.D.

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Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01GM053793 (GOLDBERG, IRVING H) Dec 15, 1995 - Nov 30, 2007
    NIH/NIGMS
    MOLECULAR MECHANISMS OF NUCLEIC ACID DAMAGE BY ENEDIYNES
    Role: Principal Investigator
  2. R35CA044257 (GOLDBERG, IRVING H) Jul 1, 1988 - Nov 30, 1996
    NIH/NCI
    MOLECULAR PHARMACOLOGY OF ANTICANCER DRUGS
    Role: Principal Investigator
  3. R01GM012573 (GOLDBERG, IRVING H) Jan 1, 1977 - Dec 31, 1991
    NIH/NIGMS
    MOLECULAR PHARMACOLOGY OF ANTICANCER DRUGS
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Ma D, Lin Y, Xiao Z, Kappen L, Goldberg IH, Kallmerten AE, Jones GB. Designed DNA probes from the neocarzinostatin family: impact of glycosyl linkage stereochemistry on bulge base binding. Bioorg Med Chem. 2009 Mar 15; 17(6):2428-32. PMID: 19243952.
    Citations: 1     Fields:    Translation:Cells
  2. Jones GB, Lin Y, Ma D, Xiao Z, Hwang GS, Kappen L, Goldberg IH. Congeners of the enediyne neocarzinostatin chromophore: designed agents for bulged nucleic acid targets. Curr Top Med Chem. 2008; 8(6):436-47. PMID: 18397167.
    Citations: 2     Fields:    Translation:Cells
  3. Zhang N, Lin Y, Xiao Z, Jones GB, Goldberg IH. Solution structure of a designed spirocyclic helical ligand binding at a two-base bulge site in DNA. Biochemistry. 2007 Apr 24; 46(16):4793-803. PMID: 17388570.
    Citations: 2     Fields:    
  4. Kappen LS, Lin Y, Jones GB, Goldberg IH. Probing DNA bulges with designed helical spirocyclic molecules. Biochemistry. 2007 Jan 16; 46(2):561-7. PMID: 17209566.
    Citations: 4     Fields:    Translation:Cells
  5. Jones GB, Lin Y, Xiao Z, Kappen L, Goldberg IH. Molecular probes of DNA bulges: functional assay and spectroscopic analysis. Bioorg Med Chem. 2007 Jan 15; 15(2):784-90. PMID: 17085052.
    Citations: 4     Fields:    Translation:Cells
  6. Xiao Z, Zhang N, Lin Y, Jones GB, Goldberg IH. Spirocyclic helical compounds as binding agents for bulged RNA, including HIV-2 TAR. Chem Commun (Camb). 2006 Nov 13; (42):4431-3. PMID: 17057867.
    Citations: 3     Fields:    Translation:HumansCells
  7. Xiao Z, Kappen LS, Goldberg IH. Development of new simple molecular probes of DNA bulged structures. Bioorg Med Chem Lett. 2006 Jun 01; 16(11):2895-9. PMID: 16546380.
    Citations: 1     Fields:    Translation:Cells
  8. Lin Y, Jones GB, Hwang GS, Kappen L, Goldberg IH. Convenient synthesis of NCS-chromophore metabolite isosteres: binding agents for bulged DNA microenvironments. Org Lett. 2005 Jan 06; 7(1):71-4. PMID: 15624980.
    Citations: 4     Fields:    Translation:Cells
  9. Gaikwad NW, Hwang GS, Goldberg IH. Synthesis and NMR binding study of a chiral spirocyclic helical analogue of a natural DNA bulge binder. Org Lett. 2004 Dec 23; 6(26):4833-6. PMID: 15606078.
    Citations: 1     Fields:    Translation:Cells
  10. Fouad FS, Xi Z, Goldberg IH, Jones GB. Preparation of alkylation agents for bulged DNA microenvironments. Bioorg Med Chem Lett. 2004 Jun 21; 14(12):3337-9. PMID: 15149702.
    Citations:    Fields:    Translation:Cells
  11. Hwang GS, Jones GB, Goldberg IH. Stereochemical control of small molecule binding to bulged DNA: comparison of structures of spirocyclic enantiomer-bulged DNA complexes. Biochemistry. 2004 Jan 27; 43(3):641-50. PMID: 14730968.
    Citations: 4     Fields:    Translation:Cells
  12. Hwang GS, Jones GB, Goldberg IH. Solution structure of a wedge-shaped synthetic molecule at a two-base bulge site in DNA. Biochemistry. 2003 Jul 22; 42(28):8472-83. PMID: 12859193.
    Citations: 5     Fields:    Translation:Cells
  13. Kappen LS, Xi Z, Jones GB, Goldberg IH. Stimulation of DNA strand slippage synthesis by a bulge binding synthetic agent. Biochemistry. 2003 Feb 25; 42(7):2166-73. PMID: 12590606.
    Citations: 3     Fields:    Translation:Cells
  14. Kwon Y, Xi Z, Kappen LS, Goldberg IH, Gao X. New complex of post-activated neocarzinostatin chromophore with DNA: bulge DNA binding from the minor groove. Biochemistry. 2003 Feb 11; 42(5):1186-98. PMID: 12564921.
    Citations: 1     Fields:    Translation:Cells
  15. Xi Z, Hwang GS, Goldberg IH, Harris JL, Pennington WT, Fouad FS, Qabaja G, Wright JM, Jones GB. Targeting DNA bulged microenvironments with synthetic agents: lessons from a natural product. Chem Biol. 2002 Aug; 9(8):925-31. PMID: 12204692.
    Citations: 6     Fields:    Translation:Cells
  16. Yang CF, Jackson PJ, Xi Z, Goldberg IH. Recognition of bulged DNA by a neocarzinostatin product via an induced fit mechanism. Bioorg Med Chem. 2002 May; 10(5):1329-35. PMID: 11886796.
    Citations:    Fields:    Translation:Cells
  17. Gao X, Stassinopoulos A, Ji J, Kwon Y, Bare S, Goldberg IH. Induced formation of a DNA bulge structure by a molecular wedge ligand-postactivated neocarzinostatin chromophore. Biochemistry. 2002 Apr 23; 41(16):5131-43. PMID: 11955061.
    Citations: 5     Fields:    Translation:Cells
  18. Jiang ZH, Hwang GS, Xi Z, Goldberg IH. Formation and structure of a novel enediyne-RNA base covalent adduct. J Am Chem Soc. 2002 Apr 03; 124(13):3216-7. PMID: 11916399.
    Citations:    Fields:    
  19. Kappen LS, Xi Z, Goldberg IH. Probing DNA single strands for single-base bulges with neocarzinostatin chromophore. Biochemistry. 2001 Dec 18; 40(50):15378-83. PMID: 11735421.
    Citations: 1     Fields:    Translation:Cells
  20. Gu F, Xi Z, Goldberg IH. DNA damage by thiol-activated neocarzinostatin chromophore at bulged sites. Biochemistry. 2000 Apr 25; 39(16):4881-91. PMID: 10769146.
    Citations:    Fields:    Translation:Cells
  21. Xi Z, Jones GB, Qabaja G, Wright J, Johnson F, Goldberg IH. Synthesis and DNA binding of spirocyclic model compounds related to the neocarzinostatin chromophore. Org Lett. 1999 Nov 04; 1(9):1375-7. PMID: 10825986.
    Citations:    Fields:    
  22. Xi Z, Mao QK, Goldberg IH. Mechanistic studies on the base-catalyzed transformation of neocarzinostatin chromophore: roles of bulged DNA. Biochemistry. 1999 Apr 06; 38(14):4342-54. PMID: 10194353.
    Citations: 2     Fields:    Translation:Cells
  23. Kappen LS, Goldberg IH. Replication block by an enediyne drug-DNA deoxyribose adduct. Biochemistry. 1999 Jan 05; 38(1):235-42. PMID: 9890903.
    Citations: 1     Fields:    Translation:Cells
  24. Zhen Xi and Irving H. Goldberg. DNA- damaging Enediyne Compounds in Comprehensive Natural Products Chemistry (Barton, Nakanishi, Meth-Cohn, eds), Vol. 7,DNA and Aspects of Molecular Biology, Eric R. Kool, ed. 1999; 553-592.
  25. Zheng P, Liu CL, Xi Z, Smith RD, Goldberg IH. Characterization of a novel covalent monoadduct on the RNA overhang of an RNA-DNA hybrid induced by antitumor antibiotic neocarzinostatin. Biochemistry. 1998 Feb 10; 37(6):1706-13. PMID: 9484242.
    Citations:    Fields:    Translation:Cells
  26. Xu YJ, Xi Z, Zhen YS, Goldberg IH. Mechanism of formation of novel covalent drug.DNA interstrand cross-links and monoadducts by enediyne antitumor antibiotics. Biochemistry. 1997 Dec 02; 36(48):14975-84. PMID: 9402755.
    Citations:    Fields:    Translation:Cells
  27. Kappen LS, Goldberg IH. Characterization of a covalent monoadduct of neocarzinostatin chromophore at a DNA bulge. Biochemistry. 1997 Dec 02; 36(48):14861-7. PMID: 9398208.
    Citations: 1     Fields:    Translation:Cells
  28. Xu Yj, Xi Z, Zhen Ys, Goldberg IH. Mechanism of Formation of Novel Covalent Drug·DNA Interstrand Cross-Links and Monoadducts by Enediyne Antitumor Antibiotics Biochemistry. 1997 Dec 02; 36(48):14975-84. PMID: 9398222.
    Citations: 9     Fields:    
  29. Kappen LS, Xi Z, Goldberg IH. Effect of ribonucleotide substitution on nucleic acid bulge recognition by neocarzinostatin. Bioorg Med Chem. 1997 Jun; 5(6):1221-7. PMID: 9222515.
    Citations: 1     Fields:    Translation:Cells
  30. Xu, Y.-J., Zhen, Y.-S., and Goldberg, I.H. Enediyne C1027 induces the formation of novel covalent DNA interstrand cross-links and mono-adducts. J. Am. Chem. Soc. 1997; 119:1133-1134.
  31. Stassinopoulos A, Ji J, Gao X, Goldberg IH. Solution structure of a two-base DNA bulge complexed with an enediyne cleaving analog. Science. 1996 Jun 28; 272(5270):1943-6. PMID: 8658168.
    Citations: 10     Fields:    Translation:Cells
  32. Gao Q, Cheng X, Smith RD, Yang CF, Goldberg IH. Binding specificity of post-activated neocarzinostatin chromophore drug-bulged DNA complex studied using electrospray ionization mass spectrometry. J Mass Spectrom. 1996 Jan; 31(1):31-6. PMID: 8799259.
    Citations: 3     Fields:    Translation:Cells
  33. Stassinopoulos A, Goldberg IH. Probing the structure of long single-stranded DNA fragments with neocarzinostatin chromophore. Extension of the base-catalyzed bulge-specific reaction. Biochemistry. 1995 Nov 21; 34(46):15359-74. PMID: 7578152.
    Citations: 1     Fields:    Translation:Cells
  34. Xu YJ, Xi Z, Zhen YS, Goldberg IH. A single binding mode of activated enediyne C1027 generates two types of double-strand DNA lesions: deuterium isotope-induced shuttling between adjacent nucleotide target sites. Biochemistry. 1995 Sep 26; 34(38):12451-60. PMID: 7547991.
    Citations: 7     Fields:    Translation:Cells
  35. Zeng X, Xi Z, Kappen LS, Tan W, Goldberg IH. Double-stranded damage of DNA.RNA hybrids by neocarzinostatin chromophore: selective C-1' chemistry on the RNA strand. Biochemistry. 1995 Sep 26; 34(38):12435-44. PMID: 7547989.
    Citations: 1     Fields:    Translation:Cells
  36. Stassinopoulos A, Goldberg IH. Binding and cleavage characteristics of the complexes formed between the neocarzinostatin chromophore and single site containing oligonucleotides. Bioorg Med Chem. 1995 Jun; 3(6):713-21. PMID: 7582949.
    Citations:    Fields:    Translation:Cells
  37. Gao X, Stassinopoulos A, Gu J, Goldberg IH. NMR studies of the post-activated neocarzinostatin chromophore-DNA complex. Conformational changes induced in drug and DNA. Bioorg Med Chem. 1995 Jun; 3(6):795-809. PMID: 7582957.
    Citations: 1     Fields:    Translation:Cells
  38. Kappen LS, Goldberg IH. Bulge-specific cleavage in transactivation response region RNA and its DNA analogue by neocarzinostatin chromophore. Biochemistry. 1995 May 02; 34(17):5997-6002. PMID: 7537097.
    Citations: 3     Fields:    Translation:Cells
  39. Yang CF, Stassinopoulos A, Goldberg IH. Specific binding of the biradical analog of neocarzinostatin chromophore to bulged DNA: implications for thiol-independent cleavage. Biochemistry. 1995 Feb 21; 34(7):2267-75. PMID: 7857937.
    Citations: 2     Fields:    Translation:Cells
  40. Gao X, Stassinopoulos A, Rice JS, Goldberg IH. Structural basis for the sequence-specific DNA strand cleavage by the enediyne neocarzinostatin chromophore. Structure of the post-activated chromophore-DNA complex. Biochemistry. 1995 Jan 10; 34(1):40-9. PMID: 7819222.
    Citations: 2     Fields:    Translation:Cells
  41. Gao, X., Stassinopoulos, A., Gu, J., and Goldberg, I.H. NMR studies of the post-activated neocarzinostatin chromophore-DNA complex. Conformational changes induced in drug and DNA. Bioorg. Med. Chem,. 1995; 3:795-809.
  42. Xu YJ, Zhen YS, Goldberg IH. C1027 chromophore, a potent new enediyne antitumor antibiotic, induces sequence-specific double-strand DNA cleavage. Biochemistry. 1994 May 17; 33(19):5947-54. PMID: 8180224.
    Citations: 18     Fields:    Translation:Cells
  43. Hensens OD, Chin DH, Stassinopoulos A, Zink DL, Kappen LS, Goldberg IH. Spontaneous generation of a biradical species of neocarzinostatin chromophore: role in DNA bulge-specific cleavage. Proc Natl Acad Sci U S A. 1994 May 10; 91(10):4534-8. PMID: 8183944.
    Citations: 5     Fields:    Translation:Cells
  44. Yu L, Goldberg IH, Dedon PC. Enediyne-mediated DNA damage in nuclei is modulated at the level of the nucleosome. J Biol Chem. 1994 Feb 11; 269(6):4144-51. PMID: 8307975.
    Citations: 5     Fields:    Translation:HumansCells
  45. Kappen LS, Goldberg IH. Site-specific cleavage at a DNA bulge by neocarzinostatin chromophore via a novel mechanism. Biochemistry. 1993 Dec 07; 32(48):13138-45. PMID: 8241168.
    Citations: 6     Fields:    Translation:Cells
  46. Kappen LS, Goldberg IH. DNA conformation-induced activation of an enediyne for site-specific cleavage. Science. 1993 Sep 03; 261(5126):1319-21. PMID: 8362243.
    Citations: 8     Fields:    Translation:Cells
  47. Chin DH, Goldberg IH. Sources of hydrogen abstraction by activated neocarzinostatin chromophore. Biochemistry. 1993 Apr 13; 32(14):3611-6. PMID: 8466903.
    Citations: 1     Fields:    Translation:Cells
  48. Hensens, O.D., Helms, G.L., Zink, D.L., Chin, D.-H., Kappen, L.S., and Goldberg, I.H. Bifunctional involvement of the hydroxy naphthoate moiety in the activation of neocarzinostatin chromophore in DNA-mediated site-specific cleavage. J. Am. Chem. Soc. 1993; 115:11030-11031.
  49. Chin, D.-H. and Goldberg, I.H. Identification of the active species responsible holo-neocarzinostatin-induced DNA cleavage. J. Am. Chem. Soc. 1993; 115:9341-9342.
  50. Meschwitz SM, Schultz RG, Ashley GW, Goldberg IH. Selective abstraction of 2H from C-1' of the C residue in AGC.ICT by the radical center at C-2 of activated neocarzinostatin chromophore: structure of the drug/DNA complex responsible for bistranded lesion formation. Biochemistry. 1992 Sep 29; 31(38):9117-21. PMID: 1390698.
    Citations: 3     Fields:    Translation:Cells
  51. Kappen LS, Goldberg IH. Mismatch-induced switch of neocarzinostatin attack sites in the DNA minor groove. Biochemistry. 1992 Sep 22; 31(37):9081-9. PMID: 1390695.
    Citations: 1     Fields:    Translation:Cells
  52. Kappen LS, Goldberg IH. Neocarzinostatin acts as a sensitive probe of DNA microheterogeneity: switching of chemistry from C-1' to C-4' by a G.T mismatch 5' to the site of DNA damage. Proc Natl Acad Sci U S A. 1992 Aug 01; 89(15):6706-10. PMID: 1386670.
    Citations: 4     Fields:    Translation:Cells
  53. Dedon PC, Goldberg IH. Free-radical mechanisms involved in the formation of sequence-dependent bistranded DNA lesions by the antitumor antibiotics bleomycin, neocarzinostatin, and calicheamicin. Chem Res Toxicol. 1992 May-Jun; 5(3):311-32. PMID: 1380322.
    Citations: 44     Fields:    Translation:HumansAnimals
  54. Dedon PC, Jiang ZW, Goldberg IH. Neocarzinostatin-mediated DNA damage in a model AGT.ACT site: mechanistic studies of thiol-sensitive partitioning of C4' DNA damage products. Biochemistry. 1992 Feb 25; 31(7):1917-27. PMID: 1531616.
    Citations: 10     Fields:    Translation:Cells
  55. Dedon PC, Goldberg IH. Influence of thiol structure on neocarzinostatin activation and expression of DNA damage. Biochemistry. 1992 Feb 25; 31(7):1909-17. PMID: 1531615.
    Citations: 6     Fields:    
  56. Chin, D.-H. and Goldberg, I.H. Internal hydrogen abstraction by activated neocarzinostatin: Quenching of the radical at C2 by hydrogen atom transfer from the a carbon of the adducted thiol. J. Am. Chem. Soc. 1992; 114:1914-1915.
  57. Meschwitz SM, Goldberg IH. Selective abstraction of 2H from C-5' of thymidylate in an oligodeoxynucleotide by the radical center at C-6 of the diradical species of neocarzinostatin: chemical evidence for the structure of the activated drug-DNA complex. Proc Natl Acad Sci U S A. 1991 Apr 15; 88(8):3047-51. PMID: 1826561.
    Citations: 2     Fields:    Translation:Cells
  58. Kappen LS, Goldberg IH, Frank BL, Worth L, Christner DF, Kozarich JW, Stubbe J. Neocarzinostatin-induced hydrogen atom abstraction from C-4' and C-5' of the T residue at a d(GT) step in oligonucleotides: shuttling between deoxyribose attack sites based on isotope selection effects. Biochemistry. 1991 Feb 26; 30(8):2034-42. PMID: 1825606.
    Citations: 9     Fields:    Translation:Cells
  59. Frank, B.L., Worth, L., Jr., Christner, D.F., Kozarich, J.W., Stubbe, J., Kappen, L.S., and Goldberg, I.H. Sequence-specific isotope effects on the cleavage of DNA by neocarzinostatin: kinetic partitioning between 4'- and 5'-hydrogen abstraction at unique thymidine sites. J. Am. Chem. Soc. 1991; 113:2271-2275.
  60. Goldberg, I.H. Mechanism of neocarzinostatin action: role of DNA microstructure in determination of chemistry of bistranded oxidative damage. Accounts of Chemical Research. 1991; 24:191-198.
  61. Dedon PC, Goldberg IH. Sequence-specific double-strand breakage of DNA by neocarzinostatin involves different chemical mechanisms within a staggered cleavage site. J Biol Chem. 1990 Sep 05; 265(25):14713-6. PMID: 2144279.
    Citations: 12     Fields:    Translation:Cells
  62. Galat A, Goldberg IH. Molecular models of neocarzinostatin damage of DNA: analysis of sequence dependence in 5'GAGCG:5'CGCTC. Nucleic Acids Res. 1990 Apr 25; 18(8):2093-9. PMID: 2139934.
    Citations: 4     Fields:    Translation:Cells
  63. Kappen, L.S. and Goldberg, I.H; Wu, S.H. and Stubbe, J.; Worth, L. Jr. and Kozarich, J.W. Isotope effects on the sequence-specific cleavage of dC in d(AGC) sequences by neocarzinostatin: elucidation of chemistry of minor lesions. J. Am. Chem. Soc. 1990; 112:2797-2798.
  64. Lee SH, Thivierge JO, Goldberg IH. DNA microstructural requirements for neocarzinostatin chromophore-induced direct strand cleavage. Nucleic Acids Res. 1989 Jul 25; 17(14):5809-25. PMID: 2527356.
    Citations: 1     Fields:    Translation:Cells
  65. Kappen LS, Lee TR, Yang CC, Goldberg IH. Oxygen transfer from the nitro group of a nitroaromatic radiosensitizer to a DNA sugar damage product. Biochemistry. 1989 May 30; 28(11):4540-2. PMID: 2527556.
    Citations: 1     Fields:    Translation:Cells
  66. Hensens OD, Goldberg IH. Mechanism of activation of the antitumor antibiotic neocarzinostatin by mercaptan and sodium borohydride. J Antibiot (Tokyo). 1989 May; 42(5):761-8. PMID: 2524463.
    Citations: 5     Fields:    Translation:Cells
  67. Kappen LS, Goldberg IH. Identification of 2-deoxyribonolactone at the site of neocarzinostatin-induced cytosine release in the sequence d(AGC). Biochemistry. 1989 Feb 07; 28(3):1027-32. PMID: 2523732.
    Citations: 22     Fields:    Translation:Cells
  68. Lee SH, Goldberg IH. Sequence-specific, strand-selective, and directional binding of neocarzinostatin chromophore to oligodeoxyribonucleotides. Biochemistry. 1989 Feb 07; 28(3):1019-26. PMID: 2523731.
    Citations: 5     Fields:    Translation:Cells
  69. Yang, C.-C. and Goldberg, I.H. Synthesis of 1-([18O2]-2-nitro-1-imidazolyl--3-methoxy-2-propanol ([18O2]-misonidazole). J. Labelled Cpds. and Radiopharm. 1989; 27:423-434.
  70. Goldberg IH. Oxidative DNA sugar damage by targeted antibiotic free radicals. Free Radic Res Commun. 1989; 6(2-3):155-6. PMID: 2526068.
    Citations:    Fields:    Translation:Cells
  71. Hensens, O.D., Giner, J.-L., and Goldberg, I.H. Biosynthesis of NCS Chrom A, the chromophore of the antitumor antibiotic neocarzinostatin. J. Am. Chem. Soc. 1989; 111:3295-3299.
  72. Williams LD, Thivierge J, Goldberg IH. Specific binding of o-phenanthroline at a DNA structural lesion. Nucleic Acids Res. 1988 Dec 23; 16(24):11607-15. PMID: 2850540.
    Citations: 2     Fields:    Translation:Cells
  73. Chin DH, Zeng CH, Costello CE, Goldberg IH. Sites in the diyne-ene bicyclic core of neocarzinostatin chromophore responsible for hydrogen abstraction from DNA. Biochemistry. 1988 Oct 18; 27(21):8106-14. PMID: 2976601.
    Citations: 5     Fields:    Translation:Cells
  74. Kappen LS, Chen CQ, Goldberg IH. Atypical abasic sites generated by neocarzinostatin at sequence-specific cytidylate residues in oligodeoxynucleotides. Biochemistry. 1988 Jun 14; 27(12):4331-40. PMID: 2458753.
    Citations: 11     Fields:    Translation:Cells
  75. Williams LD, Goldberg IH. Selective strand scission by intercalating drugs at DNA bulges. Biochemistry. 1988 Apr 19; 27(8):3004-11. PMID: 2456781.
    Citations: 7     Fields:    Translation:Cells
  76. Lee SH, Goldberg IH. Role of epoxide in neocarzinostatin chromophore stability and action. Mol Pharmacol. 1988 Apr; 33(4):396-401. PMID: 2965788.
    Citations:    Fields:    Translation:Cells
  77. Goldberg IH, Kappen L, Chin DH. Roles of oxygen and oxygen substitutes in DNA sugar damage by antitumor antibiotics. Basic Life Sci. 1988; 49:745-57. PMID: 2977947.
    Citations:    Fields:    
  78. Galat A, Goldberg IH. Analysis of microdensitometric data in terms of probability of cleavage of DNA. Comput Appl Biosci. 1987 Nov; 3(4):333-8. PMID: 2839273.
    Citations: 3     Fields:    Translation:Cells
  79. Chin DH, Kappen LS, Goldberg IH. 3'-Formyl phosphate-ended DNA: high-energy intermediate in antibiotic-induced DNA sugar damage. Proc Natl Acad Sci U S A. 1987 Oct; 84(20):7070-4. PMID: 2959956.
    Citations: 6     Fields:    Translation:Cells
  80. Povirk LF, Goldberg IH. A role of oxidative DNA sugar damage in mutagenesis by neocarzinostatin and bleomycin. Biochimie. 1987 Aug; 69(8):815-23. PMID: 2447954.
    Citations: 2     Fields:    Translation:AnimalsCells
  81. Kappen LS, Ellenberger TE, Goldberg IH. Mechanism and base specificity of DNA Breakage in intact cells by neocarzinostatin. Biochemistry. 1987 Jan 27; 26(2):384-90. PMID: 2950923.
    Citations: 6     Fields:    Translation:HumansCells
  82. Goldberg IH. Free radical mechanisms in neocarzinostatin-induced DNA damage. Free Radic Biol Med. 1987; 3(1):41-54. PMID: 2957284.
    Citations: 17     Fields:    Translation:HumansAnimals
  83. Chin DH, Goldberg IH. Generation of superoxide free radical by neocarzinostatin and its possible role in DNA damage. Biochemistry. 1986 Mar 11; 25(5):1009-15. PMID: 3008815.
    Citations:    Fields:    Translation:AnimalsCells
  84. Povirk LF, Goldberg IH. Base substitution mutations induced in the cI gene of lambda phage by neocarzinostatin chromophore: correlation with depyrimidination hotspots at the sequence AGC. Nucleic Acids Res. 1986 Feb 11; 14(3):1417-26. PMID: 2937016.
    Citations: 8     Fields:    Translation:Cells
  85. Dasgupta D, Goldberg IH. Mode of reversible binding of neocarzinostatin chromophore to DNA: base sequence dependency of binding. Nucleic Acids Res. 1986 Jan 24; 14(2):1089-105. PMID: 2935786.
    Citations: 4     Fields:    Translation:Cells
  86. Goldberg IH, Kappen LS, Povirk LF, Chin DH. Molecular mechanism of novel DNA sugar damage by an antitumour protein antibiotic. Drugs Exp Clin Res. 1986; 12(6-7):495-505. PMID: 2943568.
    Citations: 3     Fields:    Translation:AnimalsCells
  87. Goldberg IH. Novel types of DNA-sugar damage in neocarzinostatin cytotoxicity and mutagenesis. Basic Life Sci. 1986; 38:231-44. PMID: 2943262.
    Citations: 3     Fields:    Translation:Cells
  88. Dasgupta D, Auld DS, Goldberg IH. Cryospectrokinetic evidence for the mode of reversible binding of neocarzinostatin chromophore to poly(deoxyadenylic-thymidylic acid). Biochemistry. 1985 Dec 03; 24(25):7049-54. PMID: 2935186.
    Citations:    Fields:    
  89. Dasgupta D, Goldberg IH. Mode of reversible binding of neocarzinostatin chromophore to DNA: evidence for binding via the minor groove. Biochemistry. 1985 Nov 19; 24(24):6913-20. PMID: 3000442.
    Citations: 4     Fields:    Translation:AnimalsCells
  90. Povirk LF, Goldberg IH. Detection of neocarzinostatin chromophore-deoxyribose adducts as exonuclease-resistant sites in defined-sequence DNA. Biochemistry. 1985 Jul 16; 24(15):4035-40. PMID: 2996589.
    Citations: 4     Fields:    Translation:AnimalsCells
  91. Povirk LF, Goldberg IH. Endonuclease-resistant apyrimidinic sites formed by neocarzinostatin at cytosine residues in DNA: evidence for a possible role in mutagenesis. Proc Natl Acad Sci U S A. 1985 May; 82(10):3182-6. PMID: 2582408.
    Citations: 23     Fields:    Translation:Cells
  92. Kappen LS, Goldberg IH. Activation of neocarzinostatin chromophore and formation of nascent DNA damage do not require molecular oxygen. Nucleic Acids Res. 1985 Mar 11; 13(5):1637-48. PMID: 3158880.
    Citations: 10     Fields:    Translation:Cells
  93. Favaudon V, Charnas RL, Goldberg IH. Poly(deoxyadenylic-deoxythymidylic acid) damage by radiolytically activated neocarzinostatin. Biochemistry. 1985 Jan 15; 24(2):250-9. PMID: 3156631.
    Citations: 2     Fields:    
  94. Povirk LF, Goldberg IH. Competition between anaerobic covalent linkage of neocarzinostatin chromophore to deoxyribose in DNA and oxygen-dependent strand breakage and base release. Biochemistry. 1984 Dec 18; 23(26):6304-11. PMID: 6241478.
    Citations: 6     Fields:    
  95. Chin DH, Carr SA, Goldberg IH. Incorporation of 18O2 into thymidine 5'-aldehyde in neocarzinostatin chromophore-damaged DNA. J Biol Chem. 1984 Aug 25; 259(16):9975-8. PMID: 6236217.
    Citations: 2     Fields:    Translation:AnimalsCells
  96. Charnas RL, Goldberg IH. Neocarzinostatin abstracts a hydrogen during formation of nucleotide 5'-aldehyde on DNA. Biochem Biophys Res Commun. 1984 Jul 31; 122(2):642-8. PMID: 6235811.
    Citations: 2     Fields:    
  97. Kappen LS, Goldberg IH. Nitroaromatic radiation sensitizers substitute for oxygen in neocarzinostatin-induced DNA damage. Proc Natl Acad Sci U S A. 1984 Jun; 81(11):3312-6. PMID: 6233608.
    Citations: 4     Fields:    Translation:Cells
  98. Kappen LS, Goldberg IH. Deoxyribonucleic acid damage by neocarzinostatin chromophore: strand breaks generated by selective oxidation of C-5' of deoxyribose. Biochemistry. 1983 Oct 11; 22(21):4872-8. PMID: 6227335.
    Citations: 20     Fields:    Translation:Cells
  99. Povirk LF, Goldberg IH. Stoichiometric uptake of molecular oxygen and consumption of sulfhydryl groups by neocarzinostatin chromophore bound to DNA. J Biol Chem. 1983 Oct 10; 258(19):11763-7. PMID: 6225780.
    Citations: 4     Fields:    Translation:Animals
  100. Hensens OD, Dewey RS, Liesch JM, Napier MA, Reamer RA, Smith JL, Albers-Schönberg G, Goldberg IH. Neocarzinostatin chromophore: presence of a highly strained ether ring and its reaction with mercaptan and sodium borohydride. Biochem Biophys Res Commun. 1983 Jun 15; 113(2):538-47. PMID: 6223633.
    Citations: 11     Fields:    
  101. Napier MA, Goldberg IH. Neocarzinostatin chromophore. Assignment of spectral properties and structural requirements for binding to DNA. Mol Pharmacol. 1983 Mar; 23(2):500-10. PMID: 6220205.
    Citations: 5     Fields:    Translation:Animals
  102. Povirk LF, Goldberg IH. Inhibition of mammalian deoxyribonucleic acid synthesis by neocarzinostatin: selective effect on replicon initiation in CHO cells and resistant synthesis in ataxia telangiectasia fibroblasts. Biochemistry. 1982 Nov 09; 21(23):5857-62. PMID: 6217834.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  103. Povirk LF, Goldberg IH. Neocarzinostatin chromophore-DNA adducts: evidence for a covalent linkage to the oxidized C-5' of deoxyribose. Nucleic Acids Res. 1982 Oct 25; 10(20):6255-64. PMID: 6217447.
    Citations: 3     Fields:    
  104. Kappen LS, Goldberg IH, Liesch JM. Identification of thymidine-5'-aldehyde at DNA strand breaks induced by neocarzinostatin chromophore. Proc Natl Acad Sci U S A. 1982 Feb; 79(3):744-8. PMID: 16593156.
    Citations: 12     Fields:    
  105. Povirk LF, Goldberg IH. Covalent adducts of DNA and the nonprotein chromophore of neocarzinostatin contain a modified deoxyribose. Proc Natl Acad Sci U S A. 1982 Jan; 79(2):369-73. PMID: 6210907.
    Citations: 7     Fields:    
  106. Kappen, L.S., Goldberg, I.H., and Liesch, J.M. Identification of thymidine 5'-aldehyde at DNA strand breaks induced by neocarzinostatin chromophore. Proc. Natl. Acad. Sci. USA. 1982; 79:744-748.
  107. Takeshita M, Kappen LS, Grollman AP, Eisenberg M, Goldberg IH. Strand scission of deoxyribonucleic acid by neocarzinostatin, auromomycin, and bleomycin: studies on base release and nucleotide sequence specificity. Biochemistry. 1981 Dec 22; 20(26):7599-606. PMID: 6173064.
    Citations: 24     Fields:    Translation:Cells
  108. Napier MA, Holmquist B, Strydom DJ, Goldberg IH. Neocarzinostatin chromophore: purification of the major active form and characterization of its spectral and biological properties. Biochemistry. 1981 Sep 15; 20(19):5602-8. PMID: 6457635.
    Citations: 5     Fields:    Translation:HumansCells
  109. Povirk LF, Dattagupta N, Warf BC, Goldberg IH. Neocarzinostatin chromophore binds to deoxyribonucleic acid by intercalation. Biochemistry. 1981 Jul 07; 20(14):4007-14. PMID: 6456758.
    Citations: 16     Fields:    Translation:Cells
  110. Napier MA, Goldberg IH, Hensens OD, Dewey RS, Liesch JM, Albers-Schönberg G. Neocarzinostatin chromophore: presence of a cyclic carbonate subunit and its modification in the structure of other biologically active forms. Biochem Biophys Res Commun. 1981 Jun; 100(4):1703-12. PMID: 6457603.
    Citations: 4     Fields:    Translation:Cells
  111. Hatayama T, Goldberg IH. Deoxyribonucleic acid sugar damage in the action of neocarzinostatin. Biochemistry. 1980 Dec 09; 19(25):5890-8. PMID: 6450615.
    Citations: 7     Fields:    Translation:Cells
  112. Eisenstadt E, Wolf M, Goldberg IH. Mutagenesis by neocarzinostatin in Escherichia coli and Salmonella typhimurium: requirement for umuC+ or plasmid pKM101. J Bacteriol. 1980 Nov; 144(2):656-60. PMID: 6448839.
    Citations: 9     Fields:    Translation:Cells
  113. Kappen LS, Napier MA, Goldberg IH, Samy TS. Requirement for reducing agents in deoxyribonucleic acid strand scisson by the purified chromophore of auromomycin. Biochemistry. 1980 Oct 14; 19(21):4780-5. PMID: 7426628.
    Citations: 2     Fields:    Translation:HumansCells
  114. Povirk LF, Goldberg IH. Binding of the nonprotein chromophore of neocarzinostatin to deoxyribonucleic acid. Biochemistry. 1980 Oct 14; 19(21):4773-80. PMID: 6448634.
    Citations: 12     Fields:    Translation:Cells
  115. Kappen LS, Goldberg IH. Stabilization of neocarzinostatin nonprotein chromophore activity by interaction with apoprotein and with HeLa cells. Biochemistry. 1980 Oct 14; 19(21):4786-90. PMID: 6448635.
    Citations: 11     Fields:    Translation:HumansCells
  116. Albers-Schönberg G, Dewey RS, Hensens OD, Liesch JM, Napier MA, Goldberg IH. Neocarzinostatin: chemical characterization and partial structure of the non-protein chromophore. Biochem Biophys Res Commun. 1980 Aug 14; 95(3):1351-6. PMID: 6448053.
    Citations: 4     Fields:    Translation:Cells
  117. Napier MA, Kappen LS, Goldberg IH. Effect of nonprotein chromophore removal on neocarzinostatin action. Biochemistry. 1980 Apr 29; 19(9):1767-73. PMID: 6445749.
    Citations: 7     Fields:    Translation:Cells
  118. Samy TS, Kappen LS, Goldberg IH. Reversible modification of arginine residues in neocarzinostatin. Isolation of a biologically active 89-residue fragment from the tryptic hydrolysate. J Biol Chem. 1980 Apr 25; 255(8):3420-6. PMID: 6444949.
    Citations:    Fields:    Translation:Cells
  119. Kappen LS, Napier MA, Goldberg IH. Roles of chromophore and apo-protein in neocarzinostatin action. Proc Natl Acad Sci U S A. 1980 Apr; 77(4):1970-4. PMID: 6445563.
    Citations: 18     Fields:    Translation:HumansCells
  120. Goldberg IH, Hatayama T, Kappen LS, Napier MA. DNA as a target for a protein antibiotic: molecular basis of action. Mol Biol Biochem Biophys. 1980; 32:308-22. PMID: 6449657.
    Citations:    Fields:    Translation:Cells
  121. Kappen LS, Goldberg IH. Mechanism of the effect of organic solvents and other protein denaturants of neocarzinostatin activity. Biochemistry. 1979 Dec 11; 18(25):5647-53. PMID: 160246.
    Citations: 4     Fields:    Translation:Cells
  122. Kappen LS, Goldberg IH, Samy TS. Contrasts in the actions of protein antibiotics on deoxyribonucleic acid structure and function. Biochemistry. 1979 Nov 13; 18(23):5123-7. PMID: 159069.
    Citations: 4     Fields:    Translation:HumansCells
  123. Napier MA, Holmquist B, Strydom DJ, Goldberg IH. Neocarzinostatin: spectral characterization and separation of a non-protein chromophore. Biochem Biophys Res Commun. 1979 Jul 27; 89(2):635-42. PMID: 39562.
    Citations: 18     Fields:    
  124. Hatayama T, Goldberg IH. DNA damage and repair in relation to cell killing in neocarzinostatin-treated HeLa cells. Biochim Biophys Acta. 1979 Jun 20; 563(1):59-71. PMID: 159073.
    Citations: 5     Fields:    Translation:HumansCells
  125. Kappen LS, Goldberg IH. Neocarzinostatin induction of DNA repair synthesis in HeLa cells and isolated nuclei. Biochim Biophys Acta. 1978 Oct 24; 520(3):481-9. PMID: 152651.
    Citations:    Fields:    Translation:Cells
  126. Hatayama T, Goldberg IH, Takeshita M, Grollman AP. Nucleotide specificity in DNA scission by neocarzinostatin. Proc Natl Acad Sci U S A. 1978 Aug; 75(8):3603-7. PMID: 151278.
    Citations: 14     Fields:    Translation:Cells
  127. Kappen LS, Goldberg IH. Activation and inactivation of neocarzinostatin-induced cleavage of DNA. Nucleic Acids Res. 1978 Aug; 5(8):2959-67. PMID: 151264.
    Citations: 5     Fields:    Translation:Cells
  128. Kappen LS, Goldberg IH. Gaps in DNA induced by neocarzinostatin bear 3'- and 5'-phosphoryl termini. Biochemistry. 1978 Feb 21; 17(4):729-34. PMID: 146515.
    Citations: 7     Fields:    Translation:Cells
  129. Goldberg IH, Kappen LS, Beerman TA. The nature and mechanism of the damage induced in DNA by a protein antibiotic. Adv Enzyme Regul. 1977 Oct 3-4; 16:239-54. PMID: 151496.
    Citations:    Fields:    Translation:Cells
  130. Beerman TA, Goldberg IH. The relationship between DNA strand-scission and DNA synthesis inhibition in HeLa cells treated with neocarzinostatin. Biochim Biophys Acta. 1977 Mar 18; 475(2):281-93. PMID: 139166.
    Citations: 7     Fields:    Translation:Cells
  131. Beerman TA, Poon R, Goldberg IH. Single-strand nicking of DNA in vitro by neocarzinostatin and its possible relationship to the mechanism of drug action. Biochim Biophys Acta. 1977 Mar 18; 475(2):294-306. PMID: 139167.
    Citations: 7     Fields:    Translation:Cells
  132. Kappen LS, Goldberg IH. Effect of neocarzinostatin-induced strand scission on the template activity of DNA for DNA polymerase I. Biochemistry. 1977 Feb 08; 16(3):479-85. PMID: 138435.
    Citations: 4     Fields:    Translation:Cells
  133. Poon R, Beerman TA, Goldberg IH. Characterization of DNA strand breakage in vitro by the antitumor protein neocarzinostatin. Biochemistry. 1977 Feb 08; 16(3):486-93. PMID: 189801.
    Citations: 15     Fields:    Translation:Cells
  134. Kappen LS, Goldberg IH. Analysis of the two steps in polypeptide chain initiation inhibited by pactamycin. Biochemistry. 1976 Feb 24; 15(4):811-8. PMID: 1247535.
    Citations: 8     Fields:    Translation:AnimalsCells
  135. Beerman TA, Goldberg IH, Kappen LS, Poon R, Suzuki H. Molecular basis of action of cytotoxic antibiotics. Adv Enzyme Regul. 1976; 14:207-25. PMID: 9788.
    Citations:    Fields:    Translation:Cells
  136. Suzuki H, Goldberg IH. Reversal of pactamycin inhibition of methionyl-puromycin synthesis and 80S initiation complex formation by a ribosomal joining factor. Proc Natl Acad Sci U S A. 1974 Oct; 71(10):4259-63. PMID: 4530302.
    Citations: 3     Fields:    Translation:Cells
  137. Beerman TA, Goldberg IH. DNA strand scission by the antitumor protein neocarzinostatin. Biochem Biophys Res Commun. 1974 Aug 19; 59(4):1254-61. PMID: 4369938.
    Citations: 9     Fields:    Translation:HumansCells
  138. Goldberg IH. Mechanisms of action of antitumor antibiotic inhibitors of protein synthesis. Cancer Chemother Rep. 1974 Jul-Aug; 58(4):479-89. PMID: 4859409.
    Citations: 1     Fields:    Translation:AnimalsCells
  139. Goldberg IH. Potential of actinomycin in cancer control. Cancer Chemother Rep. 1974 Jan-Feb; 58(1):81-2. PMID: 4130358.
    Citations: 1     Fields:    
  140. Kappen LS, Goldberg IH. Inhibition of globin chain initiation in reticulocyte lysates by pactamycin: accumulation of methionyl-valine. Biochem Biophys Res Commun. 1973 Oct 01; 54(3):1083-91. PMID: 4753185.
    Citations: 3     Fields:    Translation:AnimalsCells
  141. Goldberg IH, Stewart ML, Ayuso M, Kappen LS. On the mechanisms of inhibition of polypeptide synthesis by the antibiotics sparsomycin and pactamycin. Fed Proc. 1973 Jun; 32(6):1688-97. PMID: 4575886.
    Citations: 7     Fields:    Translation:Cells
  142. Kappen LS, Suzuki H, Goldberg IH. Inhibition of reticulocyte peptide-chain initiation by pactamycin: accumulation of inactive ribosomal initiation complexes. Proc Natl Acad Sci U S A. 1973 Jan; 70(1):22-6. PMID: 4509656.
    Citations: 14     Fields:    Translation:AnimalsCells
  143. Ayuso, M. and Goldberg, I.H. Pactamycin inhibition of eucaryotic polypeptide synthesis dependent on added initiation factors. Biochim. Biophys. Acta. 1973; 294:118-122.
  144. Stewart, M.L. and Goldberg, I.H. Pactamycin binding to E. coli ribosomes: Interference of formation of the protein synthesizing complex with f2 viral RNA. Biochim. Biophys. Acta. 1973; 294:123-137.
  145. Stewart-Blair ML, Yanowitz IS, Goldberg IH. Inhibition of synthesis of new globin chains in reticulocyte lysates by pactamycin. Biochemistry. 1971 Nov; 10(23):4198-206. PMID: 5126935.
    Citations: 12     Fields:    Translation:AnimalsCells
  146. Morais R, Goldberg IH. Reactivation of reduced bovine pancreatic ribonuclease by subcellular fractions from calf thyroid glands. Endocrinology. 1971 Mar; 88(3):742-6. PMID: 5541311.
    Citations:    Fields:    Translation:Animals
  147. Goldberg IH, Friedman PA. Antibiotics and nucleic acids. Annu Rev Biochem. 1971; 40:775-810. PMID: 4107711.
    Citations: 38     Fields:    Translation:Cells
  148. Goldberg IH. The interaction of actinomycin with DNA. Antibiot Chemother (1971). 1971; 17:67-86. PMID: 4142574.
    Citations: 3     Fields:    Translation:Cells
  149. Goldberg IH, Friedman PA. Specificity in the mechanism of action of antibiotic inhibitors of protein and nucleic acid synthesis. Pure Appl Chem. 1971; 28(4):499-524. PMID: 5144404.
    Citations:    Fields:    Translation:Cells
  150. Joel PB, Goldberg IH. The inhibition of RNA and DNA polymerases by hedamycin. Biochim Biophys Acta. 1970 Dec 14; 224(2):361-70. PMID: 5532029.
    Citations: 2     Fields:    Translation:Animals
  151. Joel PB, Friedman PA, Goldberg IH. Interaction of kanchanomycin with nucleic acids. 3. Contrasts in the mechanisms of inhibition of ribonucleic acid and deoxyribonucleic acid polymerase reactions. Biochemistry. 1970 Oct 27; 9(22):4421-7. PMID: 4919546.
    Citations: 1     Fields:    Translation:AnimalsCells
  152. Macdonald JS, Goldberg IH. An effect of pactamycin on the initiation of protein synthesis in reticulocytes. Biochem Biophys Res Commun. 1970 Oct 09; 41(1):1-8. PMID: 5459119.
    Citations: 16     Fields:    Translation:AnimalsCells
  153. Friedman PA, Joel PB, Goldberg IH. Interaction of kanchanomycin with nucleic acids. I. Physical properties of the complex. Biochemistry. 1969 Apr; 8(4):1535-44. PMID: 4979753.
    Citations: 1     Fields:    Translation:AnimalsCells
  154. Cohen LB, Goldberg IH, Herner AE. Inhibition by pactamycin of the initiation of protein synthesis. Effect on the 30S ribosomal subunit. Biochemistry. 1969 Apr; 8(4):1327-35. PMID: 4896458.
    Citations: 4     Fields:    Translation:Cells
  155. Friedman PA, Li TK, Goldberg IH. Interaction of kanchanomycin with nucleic acids. II. Optical rotatory dispersion and circular dichroism. Biochemistry. 1969 Apr; 8(4):1545-53. PMID: 4980349.
    Citations:    Fields:    Translation:AnimalsCells
  156. Cohen LB, Herner AE, Goldberg IH. Inhibition by pactamycin of the initiation of protein synthesis. Binding of N-acetylphenylalanyl transfer ribonucleic acid and polyuridylic acid to ribosomes. Biochemistry. 1969 Apr; 8(4):1312-26. PMID: 4896457.
    Citations: 13     Fields:    Translation:Cells
  157. Herner AE, Goldberg IH, Cohen LB. Stabilization of N-acetylphenylalanyl transfer ribonucleic acid binding to ribosomes by sparsomycin. Biochemistry. 1969 Apr; 8(4):1335-44. PMID: 4896459.
    Citations: 9     Fields:    Translation:Cells
  158. Astell CR, Suzuki DT, Klett RP, Smith M, Goldberg IH. The intracellular location of the adenine- and thymine-rich component of deoxyribonucleate in testicular cells of the crab, Cancer productus. Exp Cell Res. 1969 Jan; 54(1):3-10. PMID: 4181587.
    Citations: 3     Fields:    Translation:AnimalsCells
  159. Thompson JA, Goldberg IH. Biosynthesis of thyroglobulin and its subunits in vivo in the rat thyroid gland. Endocrinology. 1968 Apr; 82(4):805-17. PMID: 5742198.
    Citations: 5     Fields:    Translation:AnimalsCells
  160. Jayaraman J, Goldberg IH. Localization of sparsomycin action to the peptide-bond-forming step. Biochemistry. 1968 Jan; 7(1):418-21. PMID: 4921281.
    Citations: 8     Fields:    Translation:Cells
  161. Cohen LB, Goldberg IH. Inhibition of peptidyl-sRNA binding to ribosomes by pactamycin. Biochem Biophys Res Commun. 1967 Dec 15; 29(5):617-22. PMID: 4865112.
    Citations: 2     Fields:    Translation:Cells
  162. Morais R, Goldberg IH. Cell-free synthesis of thyroglobulin. Biochemistry. 1967 Aug; 6(8):2538-45. PMID: 6049475.
    Citations: 1     Fields:    Translation:AnimalsCells
  163. Cerami A, Reich E, Ward DC, Goldberg IH. The interaction of actinomycin with DNA: requirement for the 2-amino group of purines. Proc Natl Acad Sci U S A. 1967 Apr; 57(4):1036-42. PMID: 5340584.
    Citations: 19     Fields:    Translation:Cells
  164. Goldberg IH, Mitsugi K. Inhibition by sparsomycin and other antibiotics of the puromycin-induced release of polypeptide from ribosomes. Biochemistry. 1967 Feb; 6(2):383-91. PMID: 4860147.
    Citations: 14     Fields:    Translation:Cells
  165. Goldberg IH, Mitsugi K. Sparsomycin inhibition of polypeptide synthesis promoted by synthetic and natural polynucleotides. Biochemistry. 1967 Feb; 6(2):372-82. PMID: 4860146.
    Citations: 10     Fields:    Translation:Cells
  166. Goldberg IH. Comments on parasite molecular biology. Mil Med. 1966 Sep; 131(9):Suppl:1092-3. PMID: 4957815.
    Citations:    Fields:    Translation:Animals
  167. Goldberg IH, Mitsugi K. Sparsomycin, an inhibitor of aminoacyl transfer to polypeptide. Biochem Biophys Res Commun. 1966 May 25; 23(4):453-9. PMID: 5335729.
    Citations: 4     Fields:    Translation:Cells
  168. Goldberg IH. Mode of action of antibiotics. II. Drugs affecting nucleic acid and protein synthesis. Am J Med. 1965 Nov; 39(5):722-52. PMID: 5319388.
    Citations: 13     Fields:    Translation:Cells
  169. Seed RW, Goldberg IH. Iodination in relation to thyroglobulin maturation and subunit aggregation. Science. 1965 Sep 17; 149(3690):1380-2. PMID: 4157517.
    Citations: 5     Fields:    Translation:AnimalsCells
  170. Ward DC, Reich E, Goldberg IH. Base specificity in the interaction of polynucleotides with antibiotic drugs. Science. 1965 Sep 10; 149(3689):1259-63. PMID: 5318292.
    Citations: 75     Fields:    Translation:AnimalsCells
  171. Goldberg IH, Seed RW. Association of isolated labeled subunits of thyroglobulin. Biochem Biophys Res Commun. 1965 May 18; 19(5):615-22. PMID: 5834713.
    Citations: 1     Fields:    Translation:Animals
  172. SELLIN HG, GOLDBERG IH. BIOSYNTHESIS OF THYROGLOBULIN. 3. INTRACELLULAR LOCALIZATION AND PROPERTIES OF LABELED THYROID PROTEINS. J Biol Chem. 1965 Feb; 240:774-81. PMID: 14275134.
    Citations: 4     Fields:    Translation:Animals
  173. SEED RW, GOLDBERG IH. BIOSYNTHESIS OF THYROGLOBULIN. II. ROLE OF SUBUNITS, IODINATION, AND RIBONUCLEIC ACID SYNTHESIS. J Biol Chem. 1965 Feb; 240:764-73. PMID: 14275133.
    Citations: 11     Fields:    Translation:AnimalsCells
  174. KO SH, RABINOWITZ M, GOLDBERG IH. PSUEDOURIDYLIC KINASE ACITIVIY IN ESCHERICHIA COLI. Biochemistry. 1964 Dec; 3:1840-3. PMID: 14269297.
    Citations:    Fields:    Translation:Cells
  175. GOLDBERG IH, REICH E. ACTINOMYCIN INHIBITION OF RNA SYNTHESIS DIRECTED BY DNA. Fed Proc. 1964 Sep-Oct; 23:958-64. PMID: 14209828.
    Citations: 37     Fields:    
  176. Reich E, Goldberg IH. Actinomycin and nucleic acid function. Prog Nucleic Acid Res Mol Biol. 1964; 3:183-234. PMID: 4157816.
    Citations: 84     Fields:    Translation:Animals
  177. SEED RW, GOLDBERG IH. BIOSYNTHESIS OF THYROGLOBULIN: RELATIONSHIP TO RNA-TEMPLATE AND PRECURSOR PROTEIN. Proc Natl Acad Sci U S A. 1963 Aug; 50:275-82. PMID: 14060644.
    Citations: 14     Fields:    Translation:Animals
  178. SASSE L, RABINOWITZ M, GOLDBERG IH. Synthesis of polypseudouridylic acid by polynucleotide phosphorylase. Biochim Biophys Acta. 1963 Jul 30; 72:353-61. PMID: 13986657.
    Citations:    Fields:    
  179. GOLDBERG IH, RABINOWITZ M. Inhibition of RNA nucleotidyltransferase by 6-azauridine triphosphate. Biochim Biophys Acta. 1963 May 28; 72:116-9. PMID: 13948671.
    Citations:    Fields:    
  180. RABINOWITZ M, GOLDBERG IH. Glycogen synthesis and other reactions of pseudouridine diphosphate glucose. J Biol Chem. 1963 May; 238:1801. PMID: 13972881.
    Citations:    Fields:    Translation:Cells
  181. GOLDBERG IH, RABINOWITZ M. Comparative utilization of pseudouridine triphosphate and uridine triphosphate by ribonucleic acid polymerase. J Biol Chem. 1963 May; 238:1793-800. PMID: 13948670.
    Citations:    Fields:    
  182. GOLDBERG IH, RABINOWITZ M, REICH E. Basis of actinomycin action. II. Effect of actinomycin on the nucleoside triphosphate-inorganic pyrophosphate exchange. Proc Natl Acad Sci U S A. 1963 Feb 15; 49:226-9. PMID: 13948668.
    Citations: 6     Fields:    Translation:Humans
  183. Goldberg, I.H., Reich, E., and Rabinowitz, M. Inhibition of ribonucleic acid-polymerase reactions by actinomycin and proflavine. Nature. 1963; 199:44-46.
  184. GOLDBERG IH, RABINOWITZ M, REICH E. Basis of actinomycin action. I. DNA binding and inhibition of RNA-polymerase synthetic reactions by actinomycin. Proc Natl Acad Sci U S A. 1962 Dec 15; 48:2094-101. PMID: 13948669.
    Citations: 91     Fields:    
  185. REICH E, GOLDBERG IH, RABINOWITZ M. Structure-activity correlations of actinomycins and their derivatives. Nature. 1962 Nov 24; 196:743-8. PMID: 13973708.
    Citations: 15     Fields:    
  186. GOLDBERG IH, RABINOWITZ M. Actionmycin D inhibition of deoxyribonucleic acid-dependent synthesis of ribonucleic acid. Science. 1962 Apr 27; 136(3513):315-6. PMID: 13899696.
    Citations: 45     Fields:    
  187. Smith, M., Rammler, D.H., Goldberg, I.H., and Khorana, H.G. Specific synthesis of the C3'-C5' inter-ribonucleotide linkage. Synthesis of uridylyl-(3'-5')-uridine and uridyl-(3'-5')-adenosine. J. amer. Chem. Soc. 1962; 84:430-440.
  188. GOLDBERG IH, RABINOWITZ M. The incorporation of 5-ribosyluracil triphosphate into RNA in nuclear extracts of mammalian cells. Biochem Biophys Res Commun. 1961 Dec 20; 6:394-8. PMID: 13899698.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  189. RABINOWITZ M, GOLDBERG IH. The formation of 5-ribosyluracil diphosphoglycosyl compounds from 5-ribosyluracil triphosphate. J Biol Chem. 1961 Dec; 236:PC79-PC80. PMID: 14489624.
    Citations:    Fields:    
  190. GOLDBERG IH, RABINOWITZ M. The enzymic synthesis of pseudouridine triphosphate. Biochim Biophys Acta. 1961 Nov 25; 54:202-4. PMID: 13899697.
    Citations: 1     Fields:    
  191. GOLDBERG IH. Ribonucleic acid synthesis in nuclear extracts of mammalian cells grown in suspension culture; effect of ionic strength and surface-active agents. Biochim Biophys Acta. 1961 Jul 22; 51:201-4. PMID: 13706452.
    Citations: 18     Fields:    Translation:HumansAnimalsCells
  192. GOLDBERG IH. The sulfolipids. J Lipid Res. 1961 Apr; 2:103-9. PMID: 13706453.
    Citations: 6     Fields:    
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