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Quanzheng Li, Ph.D.

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Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01AG052653 (LI, QUANZHENG) Aug 15, 2017 - Apr 30, 2021
    NIH/NIA
    Study of Brain Spreading Pathways of Tau and Amyloid-Beta in (pre)clinical AD
    Role: Principal Investigator
  2. R21EB018001 (MENG, LING-JIAN) Mar 1, 2014 - Feb 29, 2016
    NIH/NIBIB
    Superhigh Sensitivity SPECT Imaging with Dense Camera Arrays
    Role: Principal Investigator
  3. R01EB013293 (LI, QUANZHENG) Dec 15, 2011 - Nov 30, 2015
    NIH/NIBIB
    Quantitative Methods for Clinical Whole Body Dynamic PET
    Role: Principal Investigator
  4. R21CA149587 (LI, QUANZHENG) Mar 1, 2010 - Feb 28, 2014
    NIH/NCI
    An Integrated Statistical Framework for Lesion Detection Using Dynamic PET
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
List All   |   Timeline
  1. Sitek A, Li Q, El Fakhri G, Alpert NM. Validation of Bayesian analysis of compartmental kinetic models in medical imaging. Phys Med. 2016 Oct; 32(10):1252-1258. PMID: 27692754.
    View in: PubMed
  2. Lorsakul A, Fakhri GE, Worstell W, Ouyang J, Rakvongthai Y, Laine AF, Li Q. Numerical observer for atherosclerotic plaque classification in spectral computed tomography. J Med Imaging (Bellingham). 2016 Jul; 3(3):035501. PMID: 27429999; PMCID: PMC4940624 [Available on 07/12/17].
  3. Wang M, Guo N, Hu G, El Fakhri G, Zhang H, Li Q. A novel approach to assess the treatment response using Gaussian random field in PET. Med Phys. 2016 Feb; 43(2):833-42. PMID: 26843244.
    View in: PubMed
  4. Grogg KS, Toole T, Ouyang J, Zhu X, Normandin MD, Li Q, Johnson K, Alpert NM, El Fakhri G. National Electrical Manufacturers Association and Clinical Evaluation of a Novel Brain PET/CT Scanner. J Nucl Med. 2016 Apr; 57(4):646-52. PMID: 26697961.
    View in: PubMed
  5. Guo N, Zhang F, Zhang X, Guo J, Lang L, Kiesewetter DO, Niu G, Li Q, Chen X. Quantitative Evaluation of Tumor Early Response to a Vascular-Disrupting Agent with Dynamic PET. Mol Imaging Biol. 2015 Dec; 17(6):865-73. PMID: 25896816.
    View in: PubMed
  6. Hu C, Sepulcre J, Johnson KA, Fakhri GE, Lu YM, Li Q. Matched signal detection on graphs: Theory and application to brain imaging data classification. Neuroimage. 2016 Jan 15; 125:587-600. PMID: 26481679.
    View in: PubMed
  7. Dutta J, Huang C, Li Q, El Fakhri G. Pulmonary imaging using respiratory motion compensated simultaneous PET/MR. Med Phys. 2015 Jul; 42(7):4227-40. PMID: 26133621; PMCID: PMC4474958.
  8. Hu C, Cheng L, Sepulcre J, Johnson KA, Fakhri GE, Lu YM, Li Q. A spectral graph regression model for learning brain connectivity of Alzheimer's disease. PLoS One. 2015; 10(5):e0128136. PMID: 26024224.
    View in: PubMed
  9. Kim K, Ye JC, Worstell W, Ouyang J, Rakvongthai Y, El Fakhri G, Li Q. Sparse-view spectral CT reconstruction using spectral patch-based low-rank penalty. IEEE Trans Med Imaging. 2015 Mar; 34(3):748-60. PMID: 25532170.
    View in: PubMed
  10. Lorsakul A, Li Q, Trott CM, Hoog C, Petibon Y, Ouyang J, Laine AF, El Fakhri G. 4D numerical observer for lesion detection in respiratory-gated PET. Med Phys. 2014 Oct; 41(10):102504. PMID: 25281979; PMCID: PMC4281099.
  11. Zhu W, Li Q, Bai B, Conti PS, Leahy RM. Patlak image estimation from dual time-point list-mode PET data. IEEE Trans Med Imaging. 2014 Apr; 33(4):913-24. PMID: 24710160; PMCID: PMC4209255.
  12. Petibon Y, Huang C, Ouyang J, Reese TG, Li Q, Syrkina A, Chen YL, El Fakhri G. Relative role of motion and PSF compensation in whole-body oncologic PET-MR imaging. Med Phys. 2014 Apr; 41(4):042503. PMID: 24694156.
    View in: PubMed
  13. Bai B, Lin Y, Zhu W, Ren R, Li Q, Dahlbom M, DiFilippo F, Leahy RM. MAP reconstruction for Fourier rebinned TOF-PET data. Phys Med Biol. 2014 Feb 21; 59(4):925-49. PMID: 24504374; PMCID: PMC3980855.
  14. Hu C, El Fakhri G, Li Q. Evaluating structural symmetry of weighted brain networks via graph matching. Med Image Comput Comput Assist Interv. 2014; 17(Pt 2):733-40. PMID: 25485445.
    View in: PubMed
  15. Y. Lin, J. P. Haldar, Q. Li and R. M. Leahy. Sparse Constrained Mixture Modeling for the Estimation of Kinetic Parameters in Dynamic PET. IEEE Transactions on Medical Imaging. 2014; 33(1):173-185.
  16. Dutta J, Leahy RM, Li Q. Non-local means denoising of dynamic PET images. PLoS One. 2013; 8(12):e81390. PMID: 24339921.
    View in: PubMed
  17. Guo J, Guo N, Lang L, Kiesewetter DO, Xie Q, Li Q, Eden HS, Niu G, Chen X. (18)F-alfatide II and (18)F-FDG dual-tracer dynamic PET for parametric, early prediction of tumor response to therapy. J Nucl Med. 2014 Jan; 55(1):154-60. PMID: 24232871; PMCID: PMC4209961.
  18. Lin Y, Haldar JP, Li Q, Conti PS, Leahy RM. Sparsity Constrained Mixture Modeling for the Estimation of Kinetic Parameters in Dynamic PET. IEEE Trans Med Imaging. 2014 Jan; 33(1):173-85. PMID: 24216681; PMCID: PMC4013253.
  19. Dutta J, Ahn S, Li Q. Quantitative statistical methods for image quality assessment. Theranostics. 2013 Oct 04; 3(10):741-56. PMID: 24312148; PMCID: PMC3840409.
  20. Rakvongthai Y, Ouyang J, Guerin B, Li Q, Alpert NM, El Fakhri G. Direct reconstruction of cardiac PET kinetic parametric images using a preconditioned conjugate gradient approach. Med Phys. 2013 Oct; 40(10):102501. PMID: 24089922.
    View in: PubMed
  21. Li Q. Quantitative methods for molecular diagnostic and therapeutic imaging. Theranostics. 2013; 3(10):729-30. PMID: 24312146; PMCID: PMC3840407.
  22. Fisher BE, Li Q, Nacca A, Salem GJ, Song J, Yip J, Hui JS, Jakowec MW, Petzinger GM. Treadmill exercise elevates striatal dopamine D2 receptor binding potential in patients with early Parkinson's disease. Neuroreport. 2013 Jul 10; 24(10):509-14. PMID: 23636255.
    View in: PubMed
  23. Y. Petibon, J. Ouyang, T. G. Reese, C. Huang, X. Zhu, S. Y. Chun, Q. Li and G El Fakhri. A cardiac phantom study using simultaneous PET-MR defect detection. Physics in Medicine and Biology. 2013; 59(7):2085-2102.
  24. C. Hu, L. Cheng, J. Sepulcre, G. El Fakhri, Y. M. Lu and Q. Li. Matched Signal Detection on Graphs: Theory and Application to Brain Network Classification. Information Processing in Medical Imaging, Lecture Notes in Computer Science. 2013; 7917:1-12.
  25. Ouyang J, Li Q, El Fakhri G. Magnetic resonance-based motion correction for positron emission tomography imaging. Semin Nucl Med. 2013 Jan; 43(1):60-7. PMID: 23178089; PMCID: PMC3508789.
  26. Bai B, Li Q, Leahy RM. Magnetic resonance-guided positron emission tomography image reconstruction. Semin Nucl Med. 2013 Jan; 43(1):30-44. PMID: 23178087; PMCID: PMC3670801.
  27. Zhu L, Guo N, Li Q, Ma Y, Jacboson O, Lee S, Choi HS, Mansfield JR, Niu G, Chen X. Dynamic PET and Optical Imaging and Compartment Modeling using a Dual-labeled Cyclic RGD Peptide Probe. Theranostics. 2012; 2(8):746-56. PMID: 22916074; PMCID: PMC3425122.
  28. Ahn S, Cho S, Li Q, Lin Y, Leahy RM. Optimal rebinning of time-of-flight PET data. IEEE Trans Med Imaging. 2011 Oct; 30(10):1808-18. PMID: 21536530; PMCID: PMC3353661.
  29. Vuckovic MG, Li Q, Fisher B, Nacca A, Leahy RM, Walsh JP, Mukherjee J, Williams C, Jakowec MW, Petzinger GM. Exercise elevates dopamine D2 receptor in a mouse model of Parkinson's disease: in vivo imaging with [¹8F]fallypride. Mov Disord. 2010 Dec 15; 25(16):2777-84. PMID: 20960487; PMCID: PMC3273304.
  30. Somayajula S, Panagiotou C, Rangarajan A, Li Q, Arridge SR, Leahy RM. PET image reconstruction using information theoretic anatomical priors. IEEE Trans Med Imaging. 2011 Mar; 30(3):537-49. PMID: 20851790; PMCID: PMC3331595.
  31. Joshi AA, Pantazis D, Li Q, Damasio H, Shattuck DW, Toga AW, Leahy RM. Sulcal set optimization for cortical surface registration. Neuroimage. 2010 Apr 15; 50(3):950-9. PMID: 20056160; PMCID: PMC2832615.
  32. Li Z, Li Q, Pantazis D, Yu X, Conti PS, Leahy RM. Controlling familywise error rate for matched subspace detection in dynamic FDG PET. IEEE Trans Med Imaging. 2009 Oct; 28(10):1623-31. PMID: 19783499.
    View in: PubMed
  33. Joshi A, Pantazis D, Damasio H, Shattuck D, Li Q, Leahy R. Optimization of Landmark Selection for Cortical Surface Registration. Proc IEEE Comput Soc Conf Comput Vis Pattern Recognit. 2009 Jun 01; 20-25:699-706. PMID: 20717476.
    View in: PubMed
  34. Li Z, Li Q, Yu X, Conti PS, Leahy RM. Lesion detection in dynamic FDG-PET using matched subspace detection. IEEE Trans Med Imaging. 2009 Feb; 28(2):230-40. PMID: 19188110.
    View in: PubMed
  35. Cho S, Ahn S, Li Q, Leahy RM. Exact and approximate Fourier rebinning of PET data from time-of-flight to non time-of-flight. Phys Med Biol. 2009 Feb 07; 54(3):467-84. PMID: 19124956; PMCID: PMC4608752.
  36. Cho S, Ahn S, Li Q, Leahy RM. Analytical properties of time-of-flight PET data. Phys Med Biol. 2008 Jun 07; 53(11):2809-21. PMID: 18460746; PMCID: PMC4608751.
  37. Cho S, Li Q, Ahn S, Bai B, Leahy RM. Iterative image reconstruction using inverse Fourier rebinning for fully 3-D PET. IEEE Trans Med Imaging. 2007 May; 26(5):745-56. PMID: 17518067.
    View in: PubMed
  38. Cho S, Li Q, Ahn S, Bai B, Leahy RM. Iterative image reconstruction using inverse fourier rebinning for fully 3-D PET. IEEE Trans Med Imaging. 2007 Mar; 26(3):347-58. PMID: 17354640.
    View in: PubMed
  39. Li Q, Asma E, Ahn S, Leahy RM. A fast fully 4-D incremental gradient reconstruction algorithm for list mode PET data. IEEE Trans Med Imaging. 2007 Jan; 26(1):58-67. PMID: 17243584.
    View in: PubMed
  40. Li Q, Leahy RM. Statistical modeling and reconstruction of randoms precorrected PET data. IEEE Trans Med Imaging. 2006 Dec; 25(12):1565-72. PMID: 17167992.
    View in: PubMed
  41. Li Q, Asma E, Qi J, Bading JR, Leahy RM. Accurate estimation of the Fisher information matrix for the PET image reconstruction problem. IEEE Trans Med Imaging. 2004 Sep; 23(9):1057-64. PMID: 15377114.
    View in: PubMed
  42. Yang Y, Tai YC, Siegel S, Newport DF, Bai B, Li Q, Leahy RM, Cherry SR. Optimization and performance evaluation of the microPET II scanner for in vivo small-animal imaging. Phys Med Biol. 2004 Jun 21; 49(12):2527-45. PMID: 15272672.
    View in: PubMed
  43. B. Bai, Q. Li, C. H. Holdsworth, E. Asma, Y. C. Tai, A. Chatziioannou and R. M. Leahy. Model Based Normalization for Iterative 3D PET Reconstruction. Physics in Medicine and Biology. 47(15):2785–2797.
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Funded by the NIH/NCATS Clinical and Translational Science Award (CTSA) program, grant number UL1TR001102, and through institutional support from Harvard University, Harvard Medical School, Harvard T.H. Chan School of Public Health, Beth Israel Deaconess Medical Center, Boston Children's Hospital, Brigham and Women's Hospital, Massachusetts General Hospital and the Dana Farber Cancer Institute.