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Alan Fine, M.D.


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Mou H, Yang Y, Riehs MA, Barrios J, Shivaraju M, Haber AL, Montoro DT, Gilmore K, Haas EA, Paunovic B, Rajagopal J, Vargas SO, Haynes RL, Fine A, Cardoso WV, Ai X. Airway basal stem cells generate distinct subpopulations of PNECs. Cell Rep. 2021 04 20; 35(3):109011. PMID: 33882306; PMCID: PMC8140387.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  2. Wang W, Cohen JA, Wallrapp A, Trieu KG, Barrios J, Shao F, Krishnamoorthy N, Kuchroo VK, Jones MR, Fine A, Bai Y, Ai X. Age-Related Dopaminergic Innervation Augments T Helper 2-Type Allergic Inflammation in the Postnatal Lung. Immunity. 2019 12 17; 51(6):1102-1118.e7. PMID: 31757673.
    Citations: 21     Fields:    Translation:HumansAnimalsCells
  3. Chen F, Shao F, Hinds A, Yao S, Ram-Mohan S, Norman TA, Krishnan R, Fine A. Retinoic acid signaling is essential for airway smooth muscle homeostasis. JCI Insight. 2018 08 23; 3(16). PMID: 30135301; PMCID: PMC6141181.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  4. Swamy L, Monach P, Fine A, Breu AC. A Veteran With Fibromyalgia Presenting With Dyspnea. Fed Pract. 2018 Aug; 35(8):22-25. PMID: 30766377; PMCID: PMC6263444.
  5. Wasserman GA, Szymaniak AD, Hinds AC, Yamamoto K, Kamata H, Smith NM, Hilliard KL, Carrieri C, Labadorf AT, Quinton LJ, Ai X, Varelas X, Chen F, Mizgerd JP, Fine A, O'Carroll D, Jones MR. Expression of Piwi protein MIWI2 defines a distinct population of multiciliated cells. J Clin Invest. 2017 Oct 02; 127(10):3866-3876. PMID: 28920925; PMCID: PMC5617666.
    Citations: 7     Fields:    Translation:AnimalsCells
  6. Chen F, Fine A. Stem Cells in Lung Injury and Repair. Am J Pathol. 2016 10; 186(10):2544-50. PMID: 27524796; PMCID: PMC5222968.
    Citations: 20     Fields:    Translation:HumansAnimalsCells
  7. Rosner SR, Ram-Mohan S, Paez-Cortez JR, Lavoie TL, Dowell ML, Yuan L, Ai X, Fine A, Aird WC, Solway J, Fredberg JJ, Krishnan R. Airway contractility in the precision-cut lung slice after cryopreservation. Am J Respir Cell Mol Biol. 2014 May; 50(5):876-81. PMID: 24313705.
    Citations: 22     Fields:    Translation:AnimalsCells
  8. Chen F, Marquez H, Kim YK, Qian J, Shao F, Fine A, Cruikshank WW, Quadro L, Cardoso WV. Prenatal retinoid deficiency leads to airway hyperresponsiveness in adult mice. J Clin Invest. 2014 Feb; 124(2):801-11. PMID: 24401276; PMCID: PMC3904614.
    Citations: 35     Fields:    Translation:AnimalsCells
  9. Aven L, Paez-Cortez J, Achey R, Krishnan R, Ram-Mohan S, Cruikshank WW, Fine A, Ai X. An NT4/TrkB-dependent increase in innervation links early-life allergen exposure to persistent airway hyperreactivity. FASEB J. 2014 Feb; 28(2):897-907. PMID: 24221086.
    Citations: 31     Fields:    Translation:Animals
  10. Dixit R, Ai X, Fine A. Derivation of lung mesenchymal lineages from the fetal mesothelium requires hedgehog signaling for mesothelial cell entry. Development. 2013 Nov; 140(21):4398-406. PMID: 24130328.
    Citations: 52     Fields:    Translation:AnimalsCells
  11. Paez-Cortez J, Krishnan R, Arno A, Aven L, Ram-Mohan S, Patel KR, Lu J, King OD, Ai X, Fine A. A new approach for the study of lung smooth muscle phenotypes and its application in a murine model of allergic airway inflammation. PLoS One. 2013; 8(9):e74469. PMID: 24040256.
    Citations: 12     Fields:    Translation:HumansAnimalsCellsPHPublic Health
  12. Ohle SJ, Anandaiah A, Fabian AJ, Fine A, Kotton DN. Maintenance and repair of the lung endothelium does not involve contributions from marrow-derived endothelial precursor cells. Am J Respir Cell Mol Biol. 2012 Jul; 47(1):11-9. PMID: 22323363.
    Citations: 16     Fields:    Translation:AnimalsCells
  13. Konter JM, Parker JL, Baez E, Li SZ, Ranscht B, Denzel M, Little FF, Nakamura K, Ouchi N, Fine A, Walsh K, Summer RS. Adiponectin attenuates lipopolysaccharide-induced acute lung injury through suppression of endothelial cell activation. J Immunol. 2012 Jan 15; 188(2):854-63. PMID: 22156343; PMCID: PMC3253176.
    Citations: 53     Fields:    Translation:HumansAnimalsCells
  14. Radzikinas K, Aven L, Jiang Z, Tran T, Paez-Cortez J, Boppidi K, Lu J, Fine A, Ai X. A Shh/miR-206/BDNF cascade coordinates innervation and formation of airway smooth muscle. J Neurosci. 2011 Oct 26; 31(43):15407-15. PMID: 22031887.
    Citations: 50     Fields:    Translation:AnimalsCells
  15. Ghosh S, Paez-Cortez JR, Boppidi K, Vasconcelos M, Roy M, Cardoso W, Ai X, Fine A. Activation dynamics and signaling properties of Notch3 receptor in the developing pulmonary artery. J Biol Chem. 2011 Jun 24; 286(25):22678-87. PMID: 21536678.
    Citations: 12     Fields:    Translation:HumansAnimalsCells
  16. Langsdorf A, Schumacher V, Shi X, Tran T, Zaia J, Jain S, Taglienti M, Kreidberg JA, Fine A, Ai X. Expression regulation and function of heparan sulfate 6-O-endosulfatases in the spermatogonial stem cell niche. Glycobiology. 2011 Feb; 21(2):152-61. PMID: 20855470.
    Citations: 22     Fields:    Translation:HumansAnimalsCells
  17. Summer R, Fiack CA, Ikeda Y, Sato K, Dwyer D, Ouchi N, Fine A, Farber HW, Walsh K. Adiponectin deficiency: a model of pulmonary hypertension associated with pulmonary vascular disease. Am J Physiol Lung Cell Mol Physiol. 2009 Sep; 297(3):L432-8. PMID: 19561137.
    Citations: 62     Fields:    Translation:HumansAnimalsCells
  18. Fine A. Breathing life into the lung stem cell field. Cell Stem Cell. 2009 Jun 05; 4(6):468-9. PMID: 19497272.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  19. Summer R, Fine A. Mesenchymal progenitor cell research: limitations and recommendations. Proc Am Thorac Soc. 2008 Aug 15; 5(6):707-10. PMID: 18684722.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  20. Wilson AA, Kwok LW, Hovav AH, Ohle SJ, Little FF, Fine A, Kotton DN. Sustained expression of alpha1-antitrypsin after transplantation of manipulated hematopoietic stem cells. Am J Respir Cell Mol Biol. 2008 Aug; 39(2):133-41. PMID: 18323534.
    Citations: 32     Fields:    Translation:HumansAnimalsCells
  21. Murphy J, Summer R, Wilson AA, Kotton DN, Fine A. The prolonged life-span of alveolar macrophages. Am J Respir Cell Mol Biol. 2008 Apr; 38(4):380-5. PMID: 18192503; PMCID: PMC2274942.
    Citations: 99     Fields:    Translation:AnimalsCells
  22. Murphy J, Summer R, Fine A. Stem cells in airway smooth muscle: state of the art. Proc Am Thorac Soc. 2008 Jan 01; 5(1):11-4. PMID: 18094079.
    Citations: 12     Fields:    Translation:HumansAnimalsCells
  23. Kotton DN, Fine A. Lung stem cells. Cell Tissue Res. 2008 Jan; 331(1):145-56. PMID: 17805578.
    Citations: 31     Fields:    Translation:HumansAnimalsCells
  24. Summer R, Fitzsimmons K, Dwyer D, Murphy J, Fine A. Isolation of an adult mouse lung mesenchymal progenitor cell population. Am J Respir Cell Mol Biol. 2007 Aug; 37(2):152-9. PMID: 17395889; PMCID: PMC1976547.
    Citations: 47     Fields:    Translation:AnimalsCells
  25. Mouquet F, Pfister O, Jain M, Oikonomopoulos A, Ngoy S, Summer R, Fine A, Liao R. Restoration of cardiac progenitor cells after myocardial infarction by self-proliferation and selective homing of bone marrow-derived stem cells. Circ Res. 2005 Nov 25; 97(11):1090-2. PMID: 16269652.
    Citations: 78     Fields:    Translation:AnimalsCells
  26. Liang SX, Summer R, Sun X, Fine A. Gene expression profiling and localization of Hoechst-effluxing CD45- and CD45+ cells in the embryonic mouse lung. Physiol Genomics. 2005 Oct 17; 23(2):172-81. PMID: 16076931.
    Citations: 7     Fields:    Translation:AnimalsCells
  27. Chang JC, Summer R, Sun X, Fitzsimmons K, Fine A. Evidence that bone marrow cells do not contribute to the alveolar epithelium. Am J Respir Cell Mol Biol. 2005 Oct; 33(4):335-42. PMID: 15961725; PMCID: PMC2715342.
    Citations: 41     Fields:    Translation:HumansAnimalsCells
  28. Pfister O, Mouquet F, Jain M, Summer R, Helmes M, Fine A, Colucci WS, Liao R. CD31- but Not CD31+ cardiac side population cells exhibit functional cardiomyogenic differentiation. Circ Res. 2005 Jul 08; 97(1):52-61. PMID: 15947249.
    Citations: 180     Fields:    Translation:AnimalsCells
  29. Summer R, Kotton DN, Liang S, Fitzsimmons K, Sun X, Fine A. Embryonic lung side population cells are hematopoietic and vascular precursors. Am J Respir Cell Mol Biol. 2005 Jul; 33(1):32-40. PMID: 15802552.
    Citations: 15     Fields:    Translation:AnimalsCells
  30. Kotton DN, Summer R, Fine A. Lung stem cells: new paradigms. Exp Hematol. 2004 Apr; 32(4):340-3. PMID: 15050743.
    Citations: 10     Fields:    Translation:HumansAnimalsCells
  31. Summer R, Kotton DN, Sun X, Fitzsimmons K, Fine A. Translational physiology: origin and phenotype of lung side population cells. Am J Physiol Lung Cell Mol Physiol. 2004 Sep; 287(3):L477-83. PMID: 15047566.
    Citations: 17     Fields:    Translation:AnimalsCells
  32. Fine A. Marrow cells as progenitors of lung tissue. Blood Cells Mol Dis. 2004 Jan-Feb; 32(1):95-6. PMID: 14757420.
    Citations: 4     Fields:    Translation:HumansCells
  33. Mogi M, Yang J, Lambert JF, Colvin GA, Shiojima I, Skurk C, Summer R, Fine A, Quesenberry PJ, Walsh K. Akt signaling regulates side population cell phenotype via Bcrp1 translocation. J Biol Chem. 2003 Oct 03; 278(40):39068-75. PMID: 12851395.
    Citations: 48     Fields:    Translation:AnimalsCells
  34. Summer R, Kotton DN, Sun X, Ma B, Fitzsimmons K, Fine A. Side population cells and Bcrp1 expression in lung. Am J Physiol Lung Cell Mol Physiol. 2003 Jul; 285(1):L97-104. PMID: 12626330.
    Citations: 82     Fields:    Translation:AnimalsCells
  35. Kotton DN, Summer RS, Sun X, Ma BY, Fine A. Stem cell antigen-1 expression in the pulmonary vascular endothelium. Am J Physiol Lung Cell Mol Physiol. 2003 Jun; 284(6):L990-6. PMID: 12611818.
    Citations: 21     Fields:    Translation:Animals
  36. Izbicki G, Or R, Christensen TG, Segel MJ, Fine A, Goldstein RH, Breuer R. Bleomycin-induced lung fibrosis in IL-4-overexpressing and knockout mice. Am J Physiol Lung Cell Mol Physiol. 2002 Nov; 283(5):L1110-6. PMID: 12376365.
    Citations: 11     Fields:    Translation:Animals
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.