Harvard Catalyst Profiles

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Dario L Ferreira De Jesus, Ph.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. De Jesus DF, Orime K, Kaminska D, Kimura T, Basile G, Wang CH, Haertle L, Riemens R, Brown NK, Hu J, Männistö V, Silva AM, Dirice E, Tseng YH, Haaf T, Pihlajamäki J, Kulkarni RN. Parental metabolic syndrome epigenetically reprograms offspring hepatic lipid metabolism in mice. J Clin Invest. 2020 05 01; 130(5):2391-2407. PMID: 32250344.
    Citations: 9     Fields:    Translation:Animals
  2. Pradas-Juni M, Hansmeier NR, Link JC, Schmidt E, Larsen BD, Klemm P, Meola N, Topel H, Loureiro R, Dhaouadi I, Kiefer CA, Schwarzer R, Khani S, Oliverio M, Awazawa M, Frommolt P, Heeren J, Scheja L, Heine M, Dieterich C, Büning H, Yang L, Cao H, Jesus DF, Kulkarni RN, Zevnik B, Tröder SE, Knippschild U, Edwards PA, Lee RG, Yamamoto M, Ulitsky I, Fernandez-Rebollo E, Vallim TQA, Kornfeld JW. A MAFG-lncRNA axis links systemic nutrient abundance to hepatic glucose metabolism. Nat Commun. 2020 01 31; 11(1):644. PMID: 32005828.
    Citations: 8     Fields:    Translation:HumansAnimals
  3. Shirakawa J, Tajima K, Okuyama T, Kyohara M, Togashi Y, De Jesus DF, Basile G, Kin T, Shapiro AMJ, Kulkarni RN, Terauchi Y. Luseogliflozin increases beta cell proliferation through humoral factors that activate an insulin receptor- and IGF-1 receptor-independent pathway. Diabetologia. 2020 03; 63(3):577-587. PMID: 31897526.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  4. Zhang Z, Zhan Q, Eckert M, Zhu A, Chryplewicz A, De Jesus DF, Ren D, Kulkarni RN, Lengyel E, He C, Chen M. RADAR: differential analysis of MeRIP-seq data with a random effect model. Genome Biol. 2019 12 23; 20(1):294. PMID: 31870409.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  5. De Jesus DF, Kulkarni RN. "Omics" and "epi-omics" underlying the ß-cell adaptation to insulin resistance. Mol Metab. 2019 09; 27S:S42-S48. PMID: 31500830.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  6. De Jesus DF, Zhang Z, Kahraman S, Brown NK, Chen M, Hu J, Gupta MK, He C, Kulkarni RN. m6A mRNA Methylation Regulates Human ß-Cell Biology in Physiological States and in Type 2 Diabetes. Nat Metab. 2019 08; 1(8):765-774. PMID: 31867565.
    Citations: 28     Translation:HumansAnimalsCells
  7. Dirice E, Kahraman S, De Jesus DF, El Ouaamari A, Basile G, Baker RL, Yigit B, Piehowski PD, Kim MJ, Dwyer AJ, Ng RWS, Schuster C, Vethe H, Martinov T, Ishikawa Y, Teo AKK, Smith RD, Hu J, Haskins K, Serwold T, Qian WJ, Fife BT, Kissler S, Kulkarni RN. Increased ß-cell proliferation before immune cell invasion prevents progression of type 1 diabetes. Nat Metab. 2019 05; 1(5):509-518. PMID: 31423480.
    Citations: 10     Translation:HumansAnimalsCells
  8. Dirice E, De Jesus DF, Kahraman S, Basile G, Ng RW, El Ouaamari A, Teo AKK, Bhatt S, Hu J, Kulkarni RN. Human duct cells contribute to ß cell compensation in insulin resistance. JCI Insight. 2019 04 18; 4(8). PMID: 30996131.
    Citations: 14     Fields:    Translation:HumansAnimalsCells
  9. Jungtrakoon P, Shirakawa J, Buranasupkajorn P, Gupta MK, De Jesus DF, Pezzolesi MG, Panya A, Hastings T, Chanprasert C, Mendonca C, Kulkarni RN, Doria A. Loss-of-Function Mutation in Thiamine Transporter 1 in a Family With Autosomal Dominant Diabetes. Diabetes. 2019 05; 68(5):1084-1093. PMID: 30833467.
    Citations: 4     Fields:    Translation:Humans
  10. Gupta MK, De Jesus DF, Kahraman S, Valdez IA, Shamsi F, Yi L, Swensen AC, Tseng YH, Qian WJ, Kulkarni RN. Insulin receptor-mediated signaling regulates pluripotency markers and lineage differentiation. Mol Metab. 2018 12; 18:153-163. PMID: 30316806.
    Citations: 7     Fields:    Translation:AnimalsCells
  11. El Ouaamari A, Dirice E, Gedeon N, Hu J, Zhou JY, Shirakawa J, Hou L, Goodman J, Karampelias C, Qiang G, Boucher J, Martinez R, Gritsenko MA, De Jesus DF, Kahraman S, Bhatt S, Smith RD, Beer HD, Jungtrakoon P, Gong Y, Goldfine AB, Liew CW, Doria A, Andersson O, Qian WJ, Remold-O'Donnell E, Kulkarni RN. SerpinB1 Promotes Pancreatic ß Cell Proliferation. Cell Metab. 2016 Jan 12; 23(1):194-205. PMID: 26701651.
    Citations: 79     Fields:    Translation:HumansAnimalsCells
  12. Gupta MK, Teo AK, Rao TN, Bhatt S, Kleinridders A, Shirakawa J, Takatani T, Hu J, De Jesus DF, Windmueller R, Wagers AJ, Kulkarni RN. Excessive Cellular Proliferation Negatively Impacts Reprogramming Efficiency of Human Fibroblasts. Stem Cells Transl Med. 2015 Oct; 4(10):1101-8. PMID: 26253715.
    Citations: 7     Fields:    Translation:HumansCells
  13. El Ouaamari A, Zhou JY, Liew CW, Shirakawa J, Dirice E, Gedeon N, Kahraman S, De Jesus DF, Bhatt S, Kim JS, Clauss TR, Camp DG, Smith RD, Qian WJ, Kulkarni RN. Compensatory Islet Response to Insulin Resistance Revealed by Quantitative Proteomics. J Proteome Res. 2015 Aug 07; 14(8):3111-3122. PMID: 26151086.
    Citations: 10     Fields:    Translation:AnimalsCells
  14. Kahraman S, Dirice E, De Jesus DF, Hu J, Kulkarni RN. Maternal insulin resistance and transient hyperglycemia impact the metabolic and endocrine phenotypes of offspring. Am J Physiol Endocrinol Metab. 2014 Nov 15; 307(10):E906-18. PMID: 25249504.
    Citations: 14     Fields:    Translation:AnimalsCells
  15. De Jesus DF, Kulkarni RN. Epigenetic modifiers of islet function and mass. Trends Endocrinol Metab. 2014 Dec; 25(12):628-36. PMID: 25246382.
    Citations: 9     Fields:    Translation:HumansCells
  16. Dirice E, Kahraman S, Jiang W, El Ouaamari A, De Jesus DF, Teo AK, Hu J, Kawamori D, Gaglia JL, Mathis D, Kulkarni RN. Soluble factors secreted by T cells promote ß-cell proliferation. Diabetes. 2014 Jan; 63(1):188-202. PMID: 24089508.
    Citations: 37     Fields:    Translation:AnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.