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Nicholas Willis, Ph.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Panday A, Willis NA, Elango R, Menghi F, Duffey EE, Liu ET, Scully R. FANCM regulates repair pathway choice at stalled replication forks. Mol Cell. 2021 Apr 16. PMID: 33882298.
    Citations:    Fields:    
  2. Willis NA, Scully R. Measurement of Homologous Recombination at Stalled Mammalian Replication Forks. Methods Mol Biol. 2021; 2153:329-353. PMID: 32840790.
    Citations:    Fields:    Translation:AnimalsCells
  3. Luo ML, Zheng F, Chen W, Liang ZM, Chandramouly G, Tan J, Willis NA, Chen CH, Taveira MO, Zhou XZ, Lu KP, Scully R, Wulf GM, Hu H. Inactivation of the Prolyl Isomerase Pin1 Sensitizes BRCA1-Proficient Breast Cancer to PARP Inhibition. Cancer Res. 2020 07 15; 80(14):3033-3045. PMID: 32193285.
    Citations: 4     Fields:    Translation:HumansCells
  4. Scully R, Panday A, Elango R, Willis NA. DNA double-strand break repair-pathway choice in somatic mammalian cells. Nat Rev Mol Cell Biol. 2019 11; 20(11):698-714. PMID: 31263220.
    Citations: 110     Fields:    Translation:HumansAnimalsCells
  5. Willis NA, Panday A, Duffey EE, Scully R. Rad51 recruitment and exclusion of non-homologous end joining during homologous recombination at a Tus/Ter mammalian replication fork barrier. PLoS Genet. 2018 07; 14(7):e1007486. PMID: 30024881.
    Citations: 4     Fields:    Translation:AnimalsCells
  6. Willis NA, Frock RL, Menghi F, Duffey EE, Panday A, Camacho V, Hasty EP, Liu ET, Alt FW, Scully R. Mechanism of tandem duplication formation in BRCA1-mutant cells. Nature. 2017 11 30; 551(7682):590-595. PMID: 29168504.
    Citations: 24     Fields:    Translation:HumansAnimalsCells
  7. Smith EA, Gole B, Willis NA, Soria R, Starnes LM, Krumpelbeck EF, Jegga AG, Ali AM, Guo H, Meetei AR, Andreassen PR, Kappes F, Vinnedge LM, Daniel JA, Scully R, Wiesmüller L, Wells SI. DEK is required for homologous recombination repair of DNA breaks. Sci Rep. 2017 03 20; 7:44662. PMID: 28317934.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  8. Hartlerode AJ, Willis NA, Rajendran A, Manis JP, Scully R. Correction: Complex Breakpoints and Template Switching Associated with Non-canonical Termination of Homologous Recombination in Mammalian Cells. PLoS Genet. 2016 Dec; 12(12):e1006509. PMID: 27959912.
    Citations:    Fields:    
  9. Hartlerode AJ, Willis NA, Rajendran A, Manis JP, Scully R. Complex Breakpoints and Template Switching Associated with Non-canonical Termination of Homologous Recombination in Mammalian Cells. PLoS Genet. 2016 Nov; 12(11):e1006410. PMID: 27832076.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  10. Willis NA, Scully R. DNA Polymerase ?: Duct Tape and Zip Ties for a Fragile Genome. Mol Cell. 2016 08 18; 63(4):542-544. PMID: 27540853.
    Citations:    Fields:    Translation:HumansAnimalsCells
  11. Willis NA, Zhou C, Elia AE, Murray JM, Carr AM, Elledge SJ, Rhind N. Identification of S-phase DNA damage-response targets in fission yeast reveals conservation of damage-response networks. Proc Natl Acad Sci U S A. 2016 06 28; 113(26):E3676-85. PMID: 27298342.
    Citations: 4     Fields:    Translation:AnimalsCells
  12. Willis NA, Scully R. Spatial separation of replisome arrest sites influences homologous recombination quality at a Tus/Ter-mediated replication fork barrier. . 2016 07 17; 15(14):1812-20. PMID: 27136113.
    Citations: 2     Translation:AnimalsCells
  13. Willis NA, Rass E, Scully R. Deciphering the Code of the Cancer Genome: Mechanisms of Chromosome Rearrangement. Trends Cancer. 2015 Dec 01; 1(4):217-230. PMID: 26726318.
    Citations: 24     Fields:    
  14. Elia AE, Wang DC, Willis NA, Boardman AP, Hajdu I, Adeyemi RO, Lowry E, Gygi SP, Scully R, Elledge SJ. RFWD3-Dependent Ubiquitination of RPA Regulates Repair at Stalled Replication Forks. Mol Cell. 2015 Oct 15; 60(2):280-93. PMID: 26474068.
    Citations: 39     Fields:    Translation:HumansCells
  15. Liu P, Gan W, Guo C, Xie A, Gao D, Guo J, Zhang J, Willis N, Su A, Asara JM, Scully R, Wei W. Akt-mediated phosphorylation of XLF impairs non-homologous end-joining DNA repair. Mol Cell. 2015 Feb 19; 57(4):648-661. PMID: 25661488.
    Citations: 25     Fields:    Translation:HumansCells
  16. Willis NA, Chandramouly G, Huang B, Kwok A, Follonier C, Deng C, Scully R. BRCA1 controls homologous recombination at Tus/Ter-stalled mammalian replication forks. Nature. 2014 Jun 26; 510(7506):556-9. PMID: 24776801.
    Citations: 51     Fields:    Translation:AnimalsCells
  17. Chandramouly G, Kwok A, Huang B, Willis NA, Xie A, Scully R. BRCA1 and CtIP suppress long-tract gene conversion between sister chromatids. Nat Commun. 2013; 4:2404. PMID: 23994874.
    Citations: 27     Fields:    Translation:HumansCells
  18. Chandramouly G, Willis NA, Scully R. A protective role for BRCA2 at stalled replication forks. Breast Cancer Res. 2011 Sep 07; 13(5):314. PMID: 21996371.
    Citations: 3     Fields:    Translation:HumansCells
  19. Willis N, Rhind N. Studying G2 DNA damage checkpoints using the fission yeast Schizosaccharomyces pombe. Methods Mol Biol. 2011; 782:1-12. PMID: 21870280.
    Citations: 4     Fields:    Translation:Animals
  20. Willis N, Rhind N. Studying S-phase DNA damage checkpoints using the fission yeast Schizosaccharomyces pombe. Methods Mol Biol. 2011; 782:13-21. PMID: 21870281.
    Citations: 3     Fields:    Translation:Animals
  21. Willis N, Rhind N. The fission yeast Rad32(Mre11)-Rad50-Nbs1 complex acts both upstream and downstream of checkpoint signaling in the S-phase DNA damage checkpoint. Genetics. 2010 Apr; 184(4):887-97. PMID: 20065069.
    Citations: 3     Fields:    Translation:AnimalsCells
  22. Willis N, Rhind N. Regulation of DNA replication by the S-phase DNA damage checkpoint. Cell Div. 2009 Jul 03; 4:13. PMID: 19575778.
    Citations: 27     
  23. Willis N, Rhind N. Mus81, Rhp51(Rad51), and Rqh1 form an epistatic pathway required for the S-phase DNA damage checkpoint. Mol Biol Cell. 2009 Feb; 20(3):819-33. PMID: 19037101.
    Citations: 22     Fields:    Translation:AnimalsCells
  24. Olive KP, Tuveson DA, Ruhe ZC, Yin B, Willis NA, Bronson RT, Crowley D, Jacks T. Mutant p53 gain of function in two mouse models of Li-Fraumeni syndrome. Cell. 2004 Dec 17; 119(6):847-60. PMID: 15607980.
    Citations: 539     Fields:    Translation:AnimalsCells
  25. Tuveson DA, Shaw AT, Willis NA, Silver DP, Jackson EL, Chang S, Mercer KL, Grochow R, Hock H, Crowley D, Hingorani SR, Zaks T, King C, Jacobetz MA, Wang L, Bronson RT, Orkin SH, DePinho RA, Jacks T. Endogenous oncogenic K-ras(G12D) stimulates proliferation and widespread neoplastic and developmental defects. Cancer Cell. 2004 Apr; 5(4):375-87. PMID: 15093544.
    Citations: 356     Fields:    Translation:AnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.