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Qiurong Ding, Ph.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Shao Y, Wang L, Guo N, Wang S, Yang L, Li Y, Wang M, Yin S, Han H, Zeng L, Zhang L, Hui L, Ding Q, Zhang J, Geng H, Liu M, Li D. Correction: Cas9-nickase-mediated genome editing corrects hereditary tyrosinemia in rats. J Biol Chem. 2019 May 24; 294(21):8348. PMID: 31127060.
    Citations:    
  2. Zhao G, Gong L, Su D, Jin Y, Guo C, Yue M, Yao S, Qin Z, Ye Y, Tang Y, Wu Q, Zhang J, Cui B, Ding Q, Huang H, Hu L, Chen Y, Zhang P, Hu G, Chen L, Wong KK, Gao D, Ji H. Cullin5 deficiency promotes small-cell lung cancer metastasis by stabilizing integrin ß1. J Clin Invest. 2019 Mar 01; 129(3):972-987. PMID: 30688657.
    Citations:    Fields:    
  3. Zhao Y, Feng Z, Zhang Y, Sun Y, Chen Y, Liu X, Li S, Zhou T, Chen L, Wei Y, Ma D, Lui KO, Ying H, Chen Y, Ding Q. Gain-of-Function Mutations of SLC16A11 Contribute to the Pathogenesis of Type 2 Diabetes. Cell Rep. 2019 Jan 22; 26(4):884-892.e4. PMID: 30673611.
    Citations:    Fields:    
  4. Qiu Y, Sun Y, Xu D, Yang Y, Liu X, Wei Y, Chen Y, Feng Z, Li S, Reyad-Ul Ferdous M, Zhao Y, Xu H, Lao Y, Ding Q. Screening of FDA-approved drugs identifies sutent as a modulator of UCP1 expression in brown adipose tissue. EBioMedicine. 2018 Nov; 37:344-355. PMID: 30348622.
    Citations:    Fields:    
  5. Yuan J, Ma Y, Huang T, Chen Y, Peng Y, Li B, Li J, Zhang Y, Song B, Sun X, Ding Q, Song Y, Chang X. Genetic Modulation of RNA Splicing with a CRISPR-Guided Cytidine Deaminase. Mol Cell. 2018 10 18; 72(2):380-394.e7. PMID: 30293782.
    Citations:    Fields:    
  6. Jiang Q, Li K, Lu WJ, Li S, Chen X, Liu XJ, Yuan J, Ding Q, Lan F, Cai SQ. Identification of small-molecule ion channel modulators in C. elegans channelopathy models. Nat Commun. 2018 09 26; 9(1):3941. PMID: 30258187.
    Citations:    Fields:    Translation:HumansAnimalsCells
  7. Small KS, Todorcevic M, Civelek M, El-Sayed Moustafa JS, Wang X, Simon MM, Fernandez-Tajes J, Mahajan A, Horikoshi M, Hugill A, Glastonbury CA, Quaye L, Neville MJ, Sethi S, Yon M, Pan C, Che N, Vinuela A, Tsai PC, Nag A, Buil A, Thorleifsson G, Raghavan A, Ding Q, Morris AP, Bell JT, Thorsteinsdottir U, Stefansson K, Laakso M, Dahlman I, Arner P, Gloyn AL, Musunuru K, Lusis AJ, Cox RD, Karpe F, McCarthy MI. Author Correction: Regulatory variants at KLF14 influence type 2 diabetes risk via a female-specific effect on adipocyte size and body composition. Nat Genet. 2018 09; 50(9):1342. PMID: 30087441.
    Citations:    Fields:    
  8. Li S, Li M, Liu X, Yang Y, Wei Y, Chen Y, Qiu Y, Zhou T, Feng Z, Ma D, Fang J, Ying H, Wang H, Musunuru K, Shao Z, Zhao Y, Ding Q. Genetic and Chemical Screenings Identify HDAC3 as a Key Regulator in Hepatic Differentiation of Human Pluripotent Stem Cells. Stem Cell Reports. 2018 Jul 10; 11(1):22-31. PMID: 29861165.
    Citations:    Fields:    
  9. Small KS, Todorcevic M, Civelek M, El-Sayed Moustafa JS, Wang X, Simon MM, Fernandez-Tajes J, Mahajan A, Horikoshi M, Hugill A, Glastonbury CA, Quaye L, Neville MJ, Sethi S, Yon M, Pan C, Che N, Viñuela A, Tsai PC, Nag A, Buil A, Thorleifsson G, Raghavan A, Ding Q, Morris AP, Bell JT, Thorsteinsdottir U, Stefansson K, Laakso M, Dahlman I, Arner P, Gloyn AL, Musunuru K, Lusis AJ, Cox RD, Karpe F, McCarthy MI. Regulatory variants at KLF14 influence type 2 diabetes risk via a female-specific effect on adipocyte size and body composition. Nat Genet. 2018 04; 50(4):572-580. PMID: 29632379.
    Citations: 2     Fields:    
  10. Shao Y, Wang L, Guo N, Wang S, Yang L, Li Y, Wang M, Yin S, Han H, Zeng L, Zhang L, Hui L, Ding Q, Zhang J, Geng H, Liu M, Li D. Cas9-nickase-mediated genome editing corrects hereditary tyrosinemia in rats. J Biol Chem. 2018 05 04; 293(18):6883-6892. PMID: 29507093.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  11. Huang C, Sun M, Yang Y, Wang F, Ma X, Li J, Wang Y, Ding Q, Ying H, Song H, Wu Y, Jiang Y, Jia X, Ba Q, Wang H. Titanium dioxide nanoparticles prime a specific activation state of macrophages. Nanotoxicology. 2017 Aug; 11(6):737-750. PMID: 28669258.
    Citations: 3     Fields:    Translation:AnimalsCells
  12. Liu Y, Fan C, Zhang Y, Yu X, Wu X, Zhang X, Zhao Q, Zhang H, Xie Q, Li M, Li X, Ding Q, Ying H, Li D, Zhang H. RIP1 kinase activity-dependent roles in embryonic development of Fadd-deficient mice. Cell Death Differ. 2017 08; 24(8):1459-1469. PMID: 28574501.
    Citations: 1     Fields:    Translation:AnimalsCells
  13. Zhang YY, Li C, Yao GF, Du LJ, Liu Y, Zheng XJ, Yan S, Sun JY, Liu Y, Liu MZ, Zhang X, Wei G, Tong W, Chen X, Wu Y, Sun S, Liu S, Ding Q, Yu Y, Yin H, Duan SZ. Deletion of Macrophage Mineralocorticoid Receptor Protects Hepatic Steatosis and Insulin Resistance Through ERa/HGF/Met Pathway. Diabetes. 2017 06; 66(6):1535-1547. PMID: 28325853.
    Citations: 2     Fields:    Translation:AnimalsCells
  14. Sun Y, Ding Q. Genome engineering of stem cell organoids for disease modeling. Protein Cell. 2017 05; 8(5):315-327. PMID: 28102490.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  15. Wei Y, Chen Y, Qiu Y, Zhao H, Liu G, Zhang Y, Meng Q, Wu G, Chen Y, Cai X, Wang H, Ying H, Zhou B, Liu M, Li D, Ding Q. Prevention of Muscle Wasting by CRISPR/Cas9-mediated Disruption of Myostatin In Vivo. Mol Ther. 2016 11; 24(11):1889-1891. PMID: 27916995.
    Citations: 1     Fields:    Translation:Cells
  16. Wei Y, Qiu Y, Chen Y, Liu G, Zhang Y, Xu L, Ding Q. CRISPR/Cas9 with single guide RNA expression driven by small tRNA promoters showed reduced editing efficiency compared to a U6 promoter. RNA. 2017 01; 23(1):1-5. PMID: 27742910.
    Citations: 1     Fields:    Translation:Cells
  17. Han J, Xi Q, Meng Q, Liu J, Zhang Y, Han Y, Zhuang Q, Jiang Y, Ding Q, Wu G. Interleukin-6 promotes tumor progression in colitis-associated colorectal cancer through HIF-1a regulation. Oncol Lett. 2016 Dec; 12(6):4665-4670. PMID: 28105173.
    Citations: 3     
  18. Chen Y, Liu X, Zhang Y, Wang H, Ying H, Liu M, Li D, Lui KO, Ding Q. A Self-restricted CRISPR System to Reduce Off-target Effects. Mol Ther. 2016 09; 24(9):1508-10. PMID: 27687135.
    Citations: 6     Fields:    Translation:Humans
  19. Wang X, Raghavan A, Chen T, Qiao L, Zhang Y, Ding Q, Musunuru K. CRISPR-Cas9 Targeting of PCSK9 in Human Hepatocytes In Vivo-Brief Report. Arterioscler Thromb Vasc Biol. 2016 05; 36(5):783-6. PMID: 26941020.
    Citations: 17     Fields:    Translation:HumansAnimalsCells
  20. Han J, Meng Q, Xi Q, Zhang Y, Zhuang Q, Han Y, Jiang Y, Ding Q, Wu G. Interleukin-6 stimulates aerobic glycolysis by regulating PFKFB3 at early stage of colorectal cancer. Int J Oncol. 2016 Jan; 48(1):215-24. PMID: 26530697.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  21. Han J, Jiang Y, Liu X, Meng Q, Xi Q, Zhuang Q, Han Y, Gao Y, Ding Q, Wu G. Dietary Fat Intake and Risk of Gastric Cancer: A Meta-Analysis of Observational Studies. PLoS One. 2015; 10(9):e0138580. PMID: 26402223.
    Citations: 5     Fields:    Translation:Humans
  22. Wu YT, Yue F, Wang M, Lu YL, Dai J, Ding QL, Wang HL, Chen HF, Wang XF. Hereditary protein C deficiency caused by compound heterozygous mutants in two independent Chinese families. Pathology. 2014 Dec; 46(7):630-5. PMID: 25393254.
    Citations:    Fields:    Translation:HumansAnimalsCells
  23. Veres A, Gosis BS, Ding Q, Collins R, Ragavendran A, Brand H, Erdin S, Cowan CA, Talkowski ME, Musunuru K. Low incidence of off-target mutations in individual CRISPR-Cas9 and TALEN targeted human stem cell clones detected by whole-genome sequencing. Cell Stem Cell. 2014 Jul 03; 15(1):27-30. PMID: 24996167.
    Citations: 163     Fields:    Translation:HumansCells
  24. Ding Q, Strong A, Patel KM, Ng SL, Gosis BS, Regan SN, Cowan CA, Rader DJ, Musunuru K. Permanent alteration of PCSK9 with in vivo CRISPR-Cas9 genome editing. Circ Res. 2014 Aug 15; 115(5):488-92. PMID: 24916110.
    Citations: 78     Fields:    Translation:AnimalsCells
  25. Ding Q, Cowan CA. Liver in a dish. Cell Res. 2013 Nov; 23(11):1242-3. PMID: 23979015.
    Citations:    Fields:    Translation:HumansAnimalsCells
  26. Wu X, Lu YL, Ding QL, Dai J, Xi XD, Wang HL, Wang XF. [The binding mechanisms of F VIII Trp1707Ser mutation-associated inhibitor]. Zhonghua Xue Ye Xue Za Zhi. 2013 Aug; 34(8):691-5. PMID: 23978021.
    Citations:    Fields:    Translation:HumansCells
  27. Ding Q, Regan SN, Xia Y, Oostrom LA, Cowan CA, Musunuru K. Enhanced efficiency of human pluripotent stem cell genome editing through replacing TALENs with CRISPRs. Cell Stem Cell. 2013 Apr 04; 12(4):393-4. PMID: 23561441.
    Citations: 153     Fields:    Translation:HumansCells
  28. Ding Q, Lee YK, Schaefer EA, Peters DT, Veres A, Kim K, Kuperwasser N, Motola DL, Meissner TB, Hendriks WT, Trevisan M, Gupta RM, Moisan A, Banks E, Friesen M, Schinzel RT, Xia F, Tang A, Xia Y, Figueroa E, Wann A, Ahfeldt T, Daheron L, Zhang F, Rubin LL, Peng LF, Chung RT, Musunuru K, Cowan CA. A TALEN genome-editing system for generating human stem cell-based disease models. Cell Stem Cell. 2013 Feb 07; 12(2):238-51. PMID: 23246482.
    Citations: 187     Fields:    Translation:HumansCells
  29. Jiang LL, Cao YN, Wang XF, Ding QL, Xu GQ, Zhang LW, Dai J, Lu YL, Wang HL, Xi XD. [The phenotypic and genotypic diagnosis of three Chinese patients with von Willebrand disease]. Zhonghua Nei Ke Za Zhi. 2012 Oct; 51(10):788-92. PMID: 23290978.
    Citations:    Fields:    Translation:Humans
  30. Zhu L, Wang L, Luo X, Zhang Y, Ding Q, Jiang X, Wang X, Pan Y, Chen Y. Tollip, an intracellular trafficking protein, is a novel modulator of the transforming growth factor-ß signaling pathway. J Biol Chem. 2012 Nov 16; 287(47):39653-63. PMID: 23027871.
    Citations: 18     Fields:    Translation:HumansAnimalsCells
  31. Huang H, Jin T, He J, Ding Q, Xu D, Wang L, Zhang Y, Pan Y, Wang Z, Chen Y. Progesterone and adipoQ receptor 11 links ras signaling to cardiac development in zebrafish. Arterioscler Thromb Vasc Biol. 2012 Sep; 32(9):2158-70. PMID: 22814753.
    Citations: 2     Fields:    Translation:AnimalsCells
  32. Strong A, Ding Q, Edmondson AC, Millar JS, Sachs KV, Li X, Kumaravel A, Wang MY, Ai D, Guo L, Alexander ET, Nguyen D, Lund-Katz S, Phillips MC, Morales CR, Tall AR, Kathiresan S, Fisher EA, Musunuru K, Rader DJ. Hepatic sortilin regulates both apolipoprotein B secretion and LDL catabolism. J Clin Invest. 2012 Aug; 122(8):2807-16. PMID: 22751103.
    Citations: 56     Fields:    Translation:HumansAnimalsCells
  33. Jiang LL, Wang XF, Ding QL, Xu GQ, Zhang LW, Dai J, Lu YL, Xi XD, Wang HL. [Genotype and function analyses of four inherited dysfibrinogenemia pedigree caused by Arg16 amino acid substitution in fibrinogen Aa chain]. Zhonghua Xue Ye Xue Za Zhi. 2012 Jun; 33(6):475-9. PMID: 22967385.
    Citations:    Fields:    Translation:Humans
  34. Jin T, Xu D, Ding Q, Zhang Y, Mao C, Pan Y, Wang Z, Chen Y. Identification of the topology and functional domains of PAQR10. Biochem J. 2012 May 01; 443(3):643-53. PMID: 22339580.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  35. Xia Y, Lu QY, Lu YL, Dai J, Ding QL, Wang XF, Xi XD, Wang HL. Molecular basis of type I antithrombin deficiency in two women with recurrent venous thromboembolism in the first trimester of pregnancy. Blood Cells Mol Dis. 2012 Apr 15; 48(4):254-9. PMID: 22424603.
    Citations: 1     Fields:    Translation:HumansCells
  36. Zhu TN, Zhao YQ, Ding QL, Bai X, Wang XY, Wang XF, Yang RC, Wang ZY, Hua BL, Wel XQ, Ruan CG, Schlegel N. [The activity levels and prevalence of deficiency of protein C, protein S and antithrombin in Chinese Han population]. Zhonghua Xue Ye Xue Za Zhi. 2012 Feb; 33(2):127-30. PMID: 22730664.
    Citations:    Fields:    Translation:Humans
  37. Xia Y, Ding QL, Xu GQ, Zhang LW, Dai J, Lu YL, Wang XF, Xi XD, Wang HL. [Molecular mechanisms of recurrent venous thrombosis in two pedigrees with type I antithrombin deficiency]. Zhonghua Xue Ye Xue Za Zhi. 2011 Dec; 32(12):848-53. PMID: 22339960.
    Citations:    Fields:    Translation:Humans
  38. Jin T, Ding Q, Huang H, Xu D, Jiang Y, Zhou B, Li Z, Jiang X, He J, Liu W, Zhang Y, Pan Y, Wang Z, Thomas WG, Chen Y. PAQR10 and PAQR11 mediate Ras signaling in the Golgi apparatus. Cell Res. 2012 Apr; 22(4):661-76. PMID: 21968647.
    Citations: 6     Fields:    Translation:HumansCells
  39. Qin HH, Wang XF, Ding QL, Lu YL, Dai J, Xi XD, Wang HL. [Molecular analysis of a patient with hemophilia A caused by FVIII His99Arg mutation]. Zhonghua Xue Ye Xue Za Zhi. 2011 Sep; 32(9):587-91. PMID: 22338150.
    Citations:    Fields:    Translation:Humans
  40. Luo X, Zhang Y, Ruan X, Jiang X, Zhu L, Wang X, Ding Q, Liu W, Pan Y, Wang Z, Chen Y. Fasting-induced protein phosphatase 1 regulatory subunit contributes to postprandial blood glucose homeostasis via regulation of hepatic glycogenesis. Diabetes. 2011 May; 60(5):1435-45. PMID: 21471512.
    Citations: 19     Fields:    Translation:AnimalsCells
  41. Ouyang Q, Ding QL, Huang DD, Xu GQ, Zhang LW, Dai J, Lu YL, Wang XF, Xi XD, Wang HL. [Analysis of phenotype and genotype in three Chinese pedigrees with inherited dysfibrinogenemia]. Zhonghua Xue Ye Xue Za Zhi. 2011 Mar; 32(3):153-7. PMID: 21535951.
    Citations:    Fields:    Translation:HumansCells
  42. Qin HH, Wang XF, Ding QL, Xu GQ, Zhang LW, Dai J, Lu YL, Xi XD, Wang HL. [Phenotype and genotype analysis of three Chinese pedigrees with von Willebrand disease]. Zhonghua Xue Ye Xue Za Zhi. 2011 Feb; 32(2):99-102. PMID: 21429375.
    Citations:    Fields:    Translation:Humans
  43. Luo X, Ding Q, Wang M, Li Z, Mao K, Sun B, Pan Y, Wang Z, Zang YQ, Chen Y. In vivo disruption of TGF-beta signaling by Smad7 in airway epithelium alleviates allergic asthma but aggravates lung carcinogenesis in mouse. PLoS One. 2010 Apr 13; 5(4):e10149. PMID: 20405019.
    Citations: 10     Fields:    Translation:AnimalsCells
  44. Chen Q, Lu YL, Xu GQ, Ding QL, Wang XF, Xi XD, Wang HL. [Two new mutations of AT gene in type I inherited antithrombin deficiency.]. Zhonghua Xue Ye Xue Za Zhi. 2010 Mar; 31(3):145-8. PMID: 20510100.
    Citations:    Fields:    Translation:Humans
  45. Huang DD, Wang XF, Chen HY, Xu GQ, Zhang LW, Dai J, Lu YL, Ding QL, Xi XD, Wang HL. [Analysis of phenotype and genotype in four Chinese pedigrees with inherited coagulation factor V deficiency.]. Zhonghua Xue Ye Xue Za Zhi. 2010 Mar; 31(3):149-53. PMID: 20510101.
    Citations: 1     Fields:    Translation:Humans
  46. Qiu Y, Mao T, Zhang Y, Shao M, You J, Ding Q, Chen Y, Wu D, Xie D, Lin X, Gao X, Kaufman RJ, Li W, Liu Y. A crucial role for RACK1 in the regulation of glucose-stimulated IRE1alpha activation in pancreatic beta cells. Sci Signal. 2010 Jan 26; 3(106):ra7. PMID: 20103773.
    Citations: 57     Fields:    Translation:HumansAnimalsCells
  47. Liu HC, Mao CM, Su XY, Ruan Z, Ding QL, Wang XF, Wang HL, Xi XD. [Preparation and characterization of a monoclonal antibody against human c-Kit]. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2009 Jul; 25(7):619-22. PMID: 19737481.
    Citations:    Fields:    Translation:HumansAnimals
  48. Ding Q, Wang Z, Chen Y. Endocytosis of adiponectin receptor 1 through a clathrin- and Rab5-dependent pathway. Cell Res. 2009 Mar; 19(3):317-27. PMID: 18982021.
    Citations: 13     Fields:    Translation:HumansAnimalsCells
  49. Jin PP, Wang XF, Ding QL, Fu QH, Cai XH, Shen LS, Wang HL. Ser234Leu missense mutation in the A1 domain of factor V causing moderate factor V deficiency in a Chinese family. Pathology. 2009; 41(6):566-71. PMID: 19900106.
    Citations:    Fields:    Translation:HumansAnimalsCells
  50. Feng L, Xie X, Ding Q, Luo X, He J, Fan F, Liu W, Wang Z, Chen Y. Spatial regulation of Raf kinase signaling by RKTG. Proc Natl Acad Sci U S A. 2007 Sep 04; 104(36):14348-53. PMID: 17724343.
    Citations: 39     Fields:    Translation:HumansAnimalsCells
  51. Ding Q, Jin T, Wang Z, Chen Y. Catalase potentiates retinoic acid-induced THP-1 monocyte differentiation into macrophage through inhibition of peroxisome proliferator-activated receptor gamma. J Leukoc Biol. 2007 Jun; 81(6):1568-76. PMID: 17369494.
    Citations: 10     Fields:    Translation:HumansCells
  52. Zhou RF, Fu QH, Wang WB, Xie S, Dai J, Ding QL, Wang XF, Wang HL, Wang ZY. Molecular mechanisms of antithrombin deficiency in two Chinese families. One novel and one recurrent point mutation in the antithrombin gene causing venous thrombosis. Thromb Haemost. 2005 Dec; 94(6):1172-6. PMID: 16411389.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  53. Wang WB, Fu QH, Yin J, Wu WM, Ding QL, Zhou RF, Hu YQ, Wang XF, Wang ZY, Wang HL. Factor X Shanghai and disruption of translocation to the endoplasmic reticulum. Haematologica. 2005 Dec; 90(12):1659-64. PMID: 16330440.
    Citations: 1     Fields:    Translation:HumansCells
  54. Wang WB, Fu QH, Ding QL, Zhou RF, Wu WM, Hu YQ, Wang XF, Yan LX, Wang ZY, Wang HL. Characterization of molecular defect of 13387-9delG mutated antithrombin in inherited type I antithrombin deficiency. Blood Coagul Fibrinolysis. 2005 Mar; 16(2):149-55. PMID: 15741804.
    Citations:    Fields:    Translation:HumansAnimalsCells
  55. Ding QL, Wang HL, Wang XF, Wang MS, Fu QH, Wu WM, Hu YQ, Wang ZY. [Inherited coagulation factor VII deficiency caused by double heterozygotic mutations Arg304Gln and Arg304Trp]. Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2003 Aug; 20(4):279-83. PMID: 12903033.
    Citations:    Fields:    Translation:Humans
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.