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Gabriel Kenneth Griffin, M.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Bhattacharya R, Zekavat SM, Uddin MM, Pirruccello J, Niroula A, Gibson C, Griffin GK, Libby P, Ebert BL, Bick A, Natarajan P. Association of Diet Quality With Prevalence of Clonal Hematopoiesis and Adverse Cardiovascular Events. JAMA Cardiol. 2021 Jun 09. PMID: 34106216.
    Citations:    Fields:    
  2. Griffin GK, Wu J, Iracheta-Vellve A, Patti JC, Hsu J, Davis T, Dele-Oni D, Du PP, Halawi AG, Ishizuka JJ, Kim SY, Klaeger S, Knudsen NH, Miller BC, Nguyen TH, Olander KE, Papanastasiou M, Rachimi S, Robitschek EJ, Schneider EM, Yeary MD, Zimmer MD, Jaffe JD, Carr SA, Doench JG, Haining WN, Yates KB, Manguso RT, Bernstein BE. Epigenetic silencing by SETDB1 suppresses tumour intrinsic immunogenicity. Nature. 2021 07; 595(7866):309-314. PMID: 33953401.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  3. Griffin GK, Weirather JL, Roemer MGM, Lipschitz M, Kelley A, Chen PH, Gusenleitner D, Jeter E, Pak C, Gjini E, Chapuy B, Rosenthal MH, Xu J, Chen BJ, Sohani AR, Lovitch SB, Abramson JS, Ishizuka JJ, Kim AI, Jacobson CA, LaCasce AS, Fletcher CD, Neuberg D, Freeman GJ, Hodi FS, Wright K, Ligon AH, Jacobsen ED, Armand P, Shipp MA, Rodig SJ. Spatial signatures identify immune escape via PD-1 as a defining feature of T-cell/histiocyte-rich large B-cell lymphoma. Blood. 2021 03 11; 137(10):1353-1364. PMID: 32871584.
    Citations: 5     Fields:    Translation:HumansCells
  4. Halawi A, Griffin GK. A cytokine to remember me by. Sci Immunol. 2020 12 04; 5(54). PMID: 33277374.
    Citations:    Fields:    
  5. Honigberg MC, Zekavat SM, Niroula A, Griffin GK, Bick AG, Pirruccello JP, Nakao T, Whitsel EA, Farland LV, Laurie C, Kooperberg C, Manson JE, Gabriel S, Libby P, Reiner AP, Ebert BL, Natarajan P. Premature Menopause, Clonal Hematopoiesis, and Coronary Artery Disease in Postmenopausal Women. Circulation. 2021 Feb 02; 143(5):410-423. PMID: 33161765.
    Citations: 7     Fields:    
  6. Drokhlyansky E, Smillie CS, Van Wittenberghe N, Ericsson M, Griffin GK, Eraslan G, Dionne D, Cuoco MS, Goder-Reiser MN, Sharova T, Kuksenko O, Aguirre AJ, Boland GM, Graham D, Rozenblatt-Rosen O, Xavier RJ, Regev A. The Human and Mouse Enteric Nervous System at Single-Cell Resolution. Cell. 2020 09 17; 182(6):1606-1622.e23. PMID: 32888429.
    Citations: 25     Fields:    Translation:HumansAnimalsCells
  7. Patti JC, Griffin GK. Let's talk about sex. Sci Immunol. 2020 07 03; 5(49). PMID: 32620563.
    Citations:    Fields:    Translation:Humans
  8. Nomburg J, Bullman S, Chung SS, Togami K, Walker MA, Griffin GK, Morgan EA, LeBoeuf NR, DeCaprio JA, Meyerson M, Lane AA. Comprehensive metagenomic analysis of blastic plasmacytoid dendritic cell neoplasm. Blood Adv. 2020 03 24; 4(6):1006-1011. PMID: 32182365.
    Citations:    Fields:    Translation:HumansCells
  9. Hsu J, Griffin GK. "B"-fing up immune-mediated diseases. Sci Immunol. 2020 Jan 03; 5(43). PMID: 31901071.
    Citations:    
  10. Chapuy B, Stewart C, Dunford AJ, Kim J, Wienand K, Kamburov A, Griffin GK, Chen PH, Lako A, Redd RA, Cote CM, Ducar MD, Thorner AR, Rodig SJ, Getz G, Shipp MA. Genomic analyses of PMBL reveal new drivers and mechanisms of sensitivity to PD-1 blockade. Blood. 2019 12 26; 134(26):2369-2382. PMID: 31697821.
    Citations: 13     Fields:    Translation:Humans
  11. Patel SS, Weirather JL, Lipschitz M, Lako A, Chen PH, Griffin GK, Armand P, Shipp MA, Rodig SJ. The microenvironmental niche in classic Hodgkin lymphoma is enriched for CTLA-4-positive T cells that are PD-1-negative. Blood. 2019 12 05; 134(23):2059-2069. PMID: 31697809.
    Citations: 13     Fields:    Translation:HumansCells
  12. Bick AG, Pirruccello JP, Griffin GK, Gupta N, Gabriel S, Saleheen D, Libby P, Kathiresan S, Natarajan P. Genetic Interleukin 6 Signaling Deficiency Attenuates Cardiovascular Risk in Clonal Hematopoiesis. Circulation. 2020 01 14; 141(2):124-131. PMID: 31707836.
    Citations: 43     Fields:    Translation:HumansCells
  13. Miller BC, Sen DR, Al Abosy R, Bi K, Virkud YV, LaFleur MW, Yates KB, Lako A, Felt K, Naik GS, Manos M, Gjini E, Kuchroo JR, Ishizuka JJ, Collier JL, Griffin GK, Maleri S, Comstock DE, Weiss SA, Brown FD, Panda A, Zimmer MD, Manguso RT, Hodi FS, Rodig SJ, Sharpe AH, Haining WN. Author Correction: Subsets of exhausted CD8+ T cells differentially mediate tumor control and respond to checkpoint blockade. Nat Immunol. 2019 Nov; 20(11):1556. PMID: 31582823.
    Citations: 1     Fields:    
  14. Vickovic S, Eraslan G, Salmén F, Klughammer J, Stenbeck L, Schapiro D, Äijö T, Bonneau R, Bergenstråhle L, Navarro JF, Gould J, Griffin GK, Borg Å, Ronaghi M, Frisén J, Lundeberg J, Regev A, Ståhl PL. High-definition spatial transcriptomics for in situ tissue profiling. Nat Methods. 2019 10; 16(10):987-990. PMID: 31501547.
    Citations: 104     Fields:    Translation:HumansAnimalsCells
  15. Griffin GK. Leukemic stem cells hiding in plain sight. Sci Immunol. 2019 Aug 02; 4(38). PMID: 31375528.
    Citations:    
  16. Novikov ND, Griffin GK, Dudley G, Drew M, Rojas-Rudilla V, Lindeman NI, Dorfman DM. Utility of a Simple and Robust Flow Cytometry Assay for Rapid Clonality Testing in Mature Peripheral T-Cell Lymphomas. Am J Clin Pathol. 2019 04 02; 151(5):494-503. PMID: 30715093.
    Citations: 3     Fields:    Translation:Humans
  17. Griffin GK. T cells have seen it all before. Sci Immunol. 2019 03 01; 4(33). PMID: 30824530.
    Citations:    Fields:    
  18. van Galen P, Hovestadt V, Wadsworth Ii MH, Hughes TK, Griffin GK, Battaglia S, Verga JA, Stephansky J, Pastika TJ, Lombardi Story J, Pinkus GS, Pozdnyakova O, Galinsky I, Stone RM, Graubert TA, Shalek AK, Aster JC, Lane AA, Bernstein BE. Single-Cell RNA-Seq Reveals AML Hierarchies Relevant to Disease Progression and Immunity. Cell. 2019 03 07; 176(6):1265-1281.e24. PMID: 30827681.
    Citations: 136     Fields:    Translation:HumansCells
  19. Miller BC, Sen DR, Al Abosy R, Bi K, Virkud YV, LaFleur MW, Yates KB, Lako A, Felt K, Naik GS, Manos M, Gjini E, Kuchroo JR, Ishizuka JJ, Collier JL, Griffin GK, Maleri S, Comstock DE, Weiss SA, Brown FD, Panda A, Zimmer MD, Manguso RT, Hodi FS, Rodig SJ, Sharpe AH, Haining WN. Subsets of exhausted CD8+ T cells differentially mediate tumor control and respond to checkpoint blockade. Nat Immunol. 2019 03; 20(3):326-336. PMID: 30778252.
    Citations: 231     Fields:    Translation:HumansAnimalsCells
  20. Shanmugam V, Griffin GK, Jacobsen ED, Fletcher CDM, Sholl LM, Hornick JL. Identification of diverse activating mutations of the RAS-MAPK pathway in histiocytic sarcoma. Mod Pathol. 2019 06; 32(6):830-843. PMID: 30626916.
    Citations: 12     Fields:    Translation:HumansCells
  21. Ishizuka JJ, Manguso RT, Cheruiyot CK, Bi K, Panda A, Iracheta-Vellve A, Miller BC, Du PP, Yates KB, Dubrot J, Buchumenski I, Comstock DE, Brown FD, Ayer A, Kohnle IC, Pope HW, Zimmer MD, Sen DR, Lane-Reticker SK, Robitschek EJ, Griffin GK, Collins NB, Long AH, Doench JG, Kozono D, Levanon EY, Haining WN. Loss of ADAR1 in tumours overcomes resistance to immune checkpoint blockade. Nature. 2019 01; 565(7737):43-48. PMID: 30559380.
    Citations: 104     Fields:    Translation:AnimalsCells
  22. Griffin GK. Trypping up antigenic variation in sleeping sickness. Sci Immunol. 2018 11 02; 3(29). PMID: 30389800.
    Citations:    Fields:    
  23. Honigberg MC, Westlake AA, Griffin GK, Vaidya A, Johnson JA. A Lump in the Neck. N Engl J Med. 2018 Jul 26; 379(4):e8. PMID: 30044932.
    Citations:    Fields:    Translation:HumansPHPublic Health
  24. Griffin GK. Stemming the tide of viral infection. Sci Immunol. 2018 03 02; 3(21). PMID: 29500228.
    Citations:    Fields:    Translation:AnimalsCells
  25. Plant AS, Koyama S, Sinai C, Solomon IH, Griffin GK, Ligon KL, Bandopadhayay P, Betensky R, Emerson R, Dranoff G, Kieran MW, Ritz J. Immunophenotyping of pediatric brain tumors: correlating immune infiltrate with histology, mutational load, and survival and assessing clonal T cell response. J Neurooncol. 2018 Apr; 137(2):269-278. PMID: 29322427.
    Citations: 9     Fields:    Translation:HumansCells
  26. Griffin GK. Constant attack on T cell lymphomas. Sci Immunol. 2017 12 01; 2(18). PMID: 29196452.
    Citations:    Fields:    Translation:Humans
  27. Herrera AF, Rodig SJ, Song JY, Kim Y, Griffin GK, Yang D, Nikolaenko L, Mei M, Bedell V, Dal Cin P, Pak C, Alyea EP, Budde LE, Chen R, Chen YB, Chan WC, Cutler CS, Ho VT, Koreth J, Krishnan A, Murata-Collins JL, Nikiforow S, Palmer J, Pihan GA, Pillai R, Popplewell L, Rosen ST, Siddiqi T, Sohani AR, Zain J, Kwak LW, Weisenburger DD, Weinstock DM, Soiffer RJ, Antin JH, Forman SJ, Nademanee AP, Armand P. Outcomes after Allogeneic Stem Cell Transplantation in Patients with Double-Hit and Double-Expressor Lymphoma. Biol Blood Marrow Transplant. 2018 03; 24(3):514-520. PMID: 29196080.
    Citations: 7     Fields:    Translation:HumansCTClinical Trials
  28. Griffin GK. A recycling program that keeps PD-L1 out of the cancer cell's junkyard. Sci Immunol. 2017 Sep 01; 2(15). PMID: 28864496.
    Citations:    Fields:    
  29. Andersen EF, Paxton CN, O'Malley DP, Louissaint A, Hornick JL, Griffin GK, Fedoriw Y, Kim YS, Weiss LM, Perkins SL, South ST. Genomic analysis of follicular dendritic cell sarcoma by molecular inversion probe array reveals tumor suppressor-driven biology. Mod Pathol. 2017 09; 30(9):1321-1334. PMID: 28621320.
    Citations: 3     Fields:    Translation:HumansCells
  30. Griffin GK. PD-1 blockade: It's what's for dinner. Sci Immunol. 2017 Jun 02; 2(12). PMID: 28783659.
    Citations:    Fields:    
  31. Griffin GK. It's all in the family. Sci Immunol. 2017 Mar 03; 2(9). PMID: 28783700.
    Citations:    Fields:    
  32. Montero J, Stephansky J, Cai T, Griffin GK, Cabal-Hierro L, Togami K, Hogdal LJ, Galinsky I, Morgan EA, Aster JC, Davids MS, LeBoeuf NR, Stone RM, Konopleva M, Pemmaraju N, Letai A, Lane AA. Blastic Plasmacytoid Dendritic Cell Neoplasm Is Dependent on BCL2 and Sensitive to Venetoclax. Cancer Discov. 2017 02; 7(2):156-164. PMID: 27986708.
    Citations: 47     Fields:    Translation:HumansAnimalsCells
  33. Herrera AF, Mei M, Low L, Kim HT, Griffin GK, Song JY, Merryman RW, Bedell V, Pak C, Sun H, Paris T, Stiller T, Brown JR, Budde LE, Chan WC, Chen R, Davids MS, Freedman AS, Fisher DC, Jacobsen ED, Jacobson CA, LaCasce AS, Murata-Collins J, Nademanee AP, Palmer JM, Pihan GA, Pillai R, Popplewell L, Siddiqi T, Sohani AR, Zain J, Rosen ST, Kwak LW, Weinstock DM, Forman SJ, Weisenburger DD, Kim Y, Rodig SJ, Krishnan A, Armand P. Relapsed or Refractory Double-Expressor and Double-Hit Lymphomas Have Inferior Progression-Free Survival After Autologous Stem-Cell Transplantation. J Clin Oncol. 2017 Jan; 35(1):24-31. PMID: 28034071.
    Citations: 40     Fields:    Translation:Humans
  34. Griffin GK, Sholl LM, Lindeman NI, Fletcher CD, Hornick JL. Targeted genomic sequencing of follicular dendritic cell sarcoma reveals recurrent alterations in NF-?B regulatory genes. Mod Pathol. 2016 Jan; 29(1):67-74. PMID: 26564005.
    Citations: 14     Fields:    Translation:Humans
  35. Vodopivec I, Rinehart EM, Griffin GK, Johncilla ME, Pecora N, Yokoe DS, Feske SK, Milner DA, Folkerth RD. A Cluster of CNS Infections Due to B. cereus in the Setting of Acute Myeloid Leukemia: Neuropathology in 5 Patients. J Neuropathol Exp Neurol. 2015 Oct; 74(10):1000-11. PMID: 26352989.
    Citations: 2     Fields:    Translation:HumansCells
  36. Brown JD, Lin CY, Duan Q, Griffin G, Federation A, Paranal RM, Bair S, Newton G, Lichtman A, Kung A, Yang T, Wang H, Luscinskas FW, Croce K, Bradner JE, Plutzky J. NF-?B directs dynamic super enhancer formation in inflammation and atherogenesis. Mol Cell. 2014 Oct 23; 56(2):219-231. PMID: 25263595.
    Citations: 224     Fields:    Translation:HumansAnimalsCells
  37. Shah SM, Rosenthal MH, Griffin GK, Jacobsen ED, McCleary NJ. An aggressive presentation of colorectal cancer with an atypical lymphoproliferative pattern of metastatic disease: a case report and review of the literature. Clin Colorectal Cancer. 2014 Sep; 13(3):e5-e11. PMID: 25065654.
    Citations: 5     Fields:    Translation:Humans
  38. Amabile N, Cheng S, Renard JM, Larson MG, Ghorbani A, McCabe E, Griffin G, Guerin C, Ho JE, Shaw SY, Cohen KS, Vasan RS, Tedgui A, Boulanger CM, Wang TJ. Association of circulating endothelial microparticles with cardiometabolic risk factors in the Framingham Heart Study. Eur Heart J. 2014 Nov 07; 35(42):2972-9. PMID: 24742886.
    Citations: 48     Fields:    Translation:HumansCells
  39. Griffin GK, Lichtman AH. Two sides to every proinflammatory coin: new insights into the role of dendritic cells in the regulation of T-cell driven autoimmune myocarditis. Circulation. 2013 Jun 11; 127(23):2257-60. PMID: 23671207.
    Citations: 3     Fields:    Translation:AnimalsCells
  40. Griffin GK, Lichtman AH. Why don't macrophages leave atherosclerotic lesions? Circ Res. 2012 May 11; 110(10):1273-5. PMID: 22581919.
    Citations: 1     Fields:    Translation:AnimalsCells
  41. Griffin GK, Newton G, Tarrio ML, Bu DX, Maganto-Garcia E, Azcutia V, Alcaide P, Grabie N, Luscinskas FW, Croce KJ, Lichtman AH. IL-17 and TNF-a sustain neutrophil recruitment during inflammation through synergistic effects on endothelial activation. J Immunol. 2012 Jun 15; 188(12):6287-99. PMID: 22566565.
    Citations: 115     Fields:    Translation:AnimalsCells
  42. Maganto-García E, Bu DX, Tarrio ML, Alcaide P, Newton G, Griffin GK, Croce KJ, Luscinskas FW, Lichtman AH, Grabie N. Foxp3+-inducible regulatory T cells suppress endothelial activation and leukocyte recruitment. J Immunol. 2011 Oct 01; 187(7):3521-9. PMID: 21873519.
    Citations: 29     Fields:    Translation:AnimalsCells
  43. Bu DX, Griffin G, Lichtman AH. Mechanisms for the anti-inflammatory effects of statins. Curr Opin Lipidol. 2011 Jun; 22(3):165-70. PMID: 21412153.
    Citations: 71     Fields:    Translation:HumansAnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.