This page shows the publications co-authored by Ulf Dettmer and Nagendran Ramalingam.
Temperature is a key determinant of alpha- and beta-synuclein membrane interactions in neurons. J Biol Chem. 2021 Jan-Jun; 296:100271.
Excess membrane binding of monomeric alpha-, beta-, and gamma-synuclein is invariably associated with inclusion formation and toxicity. Hum Mol Genet. 2021 Jul 12.
Rapid Alpha-Synuclein Toxicity in a Neural Cell Model and Its Rescue by a Stearoyl-CoA Desaturase Inhibitor. Int J Mol Sci. 2020 Jul 22; 21(15).
Cell models of lipid-rich a-synuclein aggregation validate known modifiers of a-synuclein biology and identify stearoyl-CoA desaturase. Proc Natl Acad Sci U S A. 2019 10 08; 116(41):20760-20769.
Studying a-Synuclein Conformation by Intact-Cell Cross-Linking. Methods Mol Biol. 2019; 1948:77-91.
Loss of native a-synuclein multimerization by strategically mutating its amphipathic helix causes abnormal vesicle interactions in neuronal cells. Hum Mol Genet. 2017 09 15; 26(18):3466-3481.
Upregulation of Cellular Palmitoylation Mitigates a-Synuclein Accumulation and Neurotoxicity. Mov Disord. 2021 02; 36(2):348-359.
Lipidomic Analysis of a-Synuclein Neurotoxicity Identifies Stearoyl CoA Desaturase as a Target for Parkinson Treatment. Mol Cell. 2019 03 07; 73(5):1001-1014.e8.
The connection strength for co-authors is the sum of the scores for each of their shared publications.
Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.