Harvard Catalyst Profiles

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Theodore Robertson Pak, M.D., Ph.D.

Other Positions

Massachusetts General Hospital, Boston, MA06/2021Residency, Internal Medicine
Icahn School of Medicine at Mount Sinai, New York, NYMD05/2019Medicine
Icahn School of Medicine at Mount Sinai, New York, NYPhD09/2017Biomedical Sciences
Harvard College, Cambridge, MAAB06/2011Biochemical Sciences


The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. F30AI122673 (PAK, THEODORE ROBERTSON) Jun 13, 2016 - Jun 12, 2020
    Multiscale analysis of immune profiling data from dengue and chikungunya virus infections in humans
    Role: Principal Investigator

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Javaid W, Ehni J, Gonzalez-Reiche AS, Carreño JM, Hirsch E, Tan J, Khan Z, Kriti D, Ly T, Kranitzky B, Barnett B, Cera F, Prespa L, Moss M, Albrecht RA, Mustafa A, Herbison I, Hernandez MM, Pak TR, Alshammary HA, Sebra R, Smith ML, Krammer F, Gitman MR, Sordillo EM, Simon V, van Bakel H. Real-Time Investigation of a Large Nosocomial Influenza A Outbreak Informed by Genomic Epidemiology. Clin Infect Dis. 2021 12 06; 73(11):e4375-e4383. PMID: 33252647.
    Citations: 2     Fields:    
  2. Berbel Caban A, Pak TR, Obla A, Dupper AC, Chacko KI, Fox L, Mills A, Ciferri B, Oussenko I, Beckford C, Chung M, Sebra R, Smith M, Conolly S, Patel G, Kasarskis A, Sullivan MJ, Altman DR, van Bakel H. PathoSPOT genomic epidemiology reveals under-the-radar nosocomial outbreaks. Genome Med. 2020 11 16; 12(1):96. PMID: 33198787.
    Citations: 2     Fields:    Translation:HumansCellsPHPublic Health
  3. Oliveira PH, Ribis JW, Garrett EM, Trzilova D, Kim A, Sekulovic O, Mead EA, Pak T, Zhu S, Deikus G, Touchon M, Lewis-Sandari M, Beckford C, Zeitouni NE, Altman DR, Webster E, Oussenko I, Bunyavanich S, Aggarwal AK, Bashir A, Patel G, Wallach F, Hamula C, Huprikar S, Schadt EE, Sebra R, van Bakel H, Kasarskis A, Tamayo R, Shen A, Fang G. Epigenomic characterization of Clostridioides difficile finds a conserved DNA methyltransferase that mediates sporulation and pathogenesis. Nat Microbiol. 2020 01; 5(1):166-180. PMID: 31768029.
    Citations: 17     Fields:    Translation:HumansAnimalsCells
  4. Sullivan MJ, Altman DR, Chacko KI, Ciferri B, Webster E, Pak TR, Deikus G, Lewis-Sandari M, Khan Z, Beckford C, Rendo A, Samaroo F, Sebra R, Karam-Howlin R, Dingle T, Hamula C, Bashir A, Schadt E, Patel G, Wallach F, Kasarskis A, Gibbs K, van Bakel H. A Complete Genome Screening Program of Clinical Methicillin-Resistant Staphylococcus aureus Isolates Identifies the Origin and Progression of a Neonatal Intensive Care Unit Outbreak. J Clin Microbiol. 2019 12; 57(12). PMID: 31578260.
    Citations: 6     Fields:    Translation:HumansCellsPHPublic Health
  5. Altman DR, Sullivan MJ, Chacko KI, Balasubramanian D, Pak TR, Sause WE, Kumar K, Sebra R, Deikus G, Attie O, Rose H, Lewis M, Fulmer Y, Bashir A, Kasarskis A, Schadt EE, Richardson AR, Torres VJ, Shopsin B, van Bakel H. Genome Plasticity of agr-Defective Staphylococcus aureus during Clinical Infection. Infect Immun. 2018 10; 86(10). PMID: 30061376.
    Citations: 23     Fields:    Translation:HumansAnimalsCells
  6. Michlmayr D, Pak TR, Rahman AH, Amir ED, Kim EY, Kim-Schulze S, Suprun M, Stewart MG, Thomas GP, Balmaseda A, Wang L, Zhu J, Suaréz-Fariñas M, Wolinsky SM, Kasarskis A, Harris E. Comprehensive innate immune profiling of chikungunya virus infection in pediatric cases. Mol Syst Biol. 2018 08 27; 14(8):e7862. PMID: 30150281.
    Citations: 28     Fields:    Translation:HumansAnimalsCells
  7. Chacko KI, Sullivan MJ, Beckford C, Altman DR, Ciferri B, Pak TR, Sebra R, Kasarskis A, Hamula CL, van Bakel H. Genetic Basis of Emerging Vancomycin, Linezolid, and Daptomycin Heteroresistance in a Case of Persistent Enterococcus faecium Bacteremia. Antimicrob Agents Chemother. 2018 04; 62(4). PMID: 29339387.
    Citations: 7     Fields:    Translation:HumansCells
  8. Pak TR, Chacko KI, O'Donnell T, Huprikar SS, van Bakel H, Kasarskis A, Scott ER. Estimating Local Costs Associated With Clostridium difficile Infection Using Machine Learning and Electronic Medical Records. Infect Control Hosp Epidemiol. 2017 12; 38(12):1478-1486. PMID: 29103378.
    Citations: 2     Fields:    Translation:HumansCells
  9. Hamlin RE, Rahman A, Pak TR, Maringer K, Mena I, Bernal-Rubio D, Potla U, Maestre AM, Fredericks AC, Amir ED, Kasarskis A, Ramos I, Merad M, Fernandez-Sesma A. High-dimensional CyTOF analysis of dengue virus-infected human DCs reveals distinct viral signatures. JCI Insight. 2017 Jul 06; 2(13). PMID: 28679950.
    Citations: 13     Fields:    
  10. Bashir A, Attie O, Sullivan M, Sebra R, Singh KV, Altman D, Pak T, Dutta J, Chacko K, Webster E, Lewis M, Hamula C, Delli Carpini KW, Murray BE, Kasarskis A, van Bakel H, Huprikar S. Genomic confirmation of vancomycin-resistant Enterococcus transmission from deceased donor to liver transplant recipient. PLoS One. 2017; 12(3):e0170449. PMID: 28301471.
    Citations: 4     Fields:    Translation:HumansCells
  11. Pak TR, Kasarskis A. Reply to Lesho. Clin Infect Dis. 2016 Apr 15; 62(8):1053. PMID: 26908789.
    Citations: 1     Fields:    Translation:Humans
  12. Pak TR, Altman DR, Attie O, Sebra R, Hamula CL, Lewis M, Deikus G, Newman LC, Fang G, Hand J, Patel G, Wallach F, Schadt EE, Huprikar S, van Bakel H, Kasarskis A, Bashir A. Whole-genome sequencing identifies emergence of a quinolone resistance mutation in a case of Stenotrophomonas maltophilia bacteremia. Antimicrob Agents Chemother. 2015 Nov; 59(11):7117-20. PMID: 26324280.
    Citations: 9     Fields:    Translation:Cells
  13. Pak TR, Kasarskis A. How next-generation sequencing and multiscale data analysis will transform infectious disease management. Clin Infect Dis. 2015 Dec 01; 61(11):1695-702. PMID: 26251049.
    Citations: 16     Fields:    Translation:Humans
  14. Finkelstein M, Siddiqui A, Pak T, Hu K, Ciccariello C, Knabben V, Chiang D, Thomas DC, Meah YS. A user-editable web-based platform to streamline clinical information flow. Stud Health Technol Inform. 2015; 210:909-13. PMID: 25991288.
    Citations: 1     Fields:    
  15. Pak TR, Roth FP. ChromoZoom: a flexible, fluid, web-based genome browser. Bioinformatics. 2013 Feb 01; 29(3):384-6. PMID: 23220575.
    Citations: 9     Fields:    Translation:HumansAnimals
  16. Rozenblatt-Rosen O, Deo RC, Padi M, Adelmant G, Calderwood MA, Rolland T, Grace M, Dricot A, Askenazi M, Tavares M, Pevzner SJ, Abderazzaq F, Byrdsong D, Carvunis AR, Chen AA, Cheng J, Correll M, Duarte M, Fan C, Feltkamp MC, Ficarro SB, Franchi R, Garg BK, Gulbahce N, Hao T, Holthaus AM, James R, Korkhin A, Litovchick L, Mar JC, Pak TR, Rabello S, Rubio R, Shen Y, Singh S, Spangle JM, Tasan M, Wanamaker S, Webber JT, Roecklein-Canfield J, Johannsen E, Barabási AL, Beroukhim R, Kieff E, Cusick ME, Hill DE, Münger K, Marto JA, Quackenbush J, Roth FP, DeCaprio JA, Vidal M. Interpreting cancer genomes using systematic host network perturbations by tumour virus proteins. Nature. 2012 Jul 26; 487(7408):491-5. PMID: 22810586.
    Citations: 213     Fields:    Translation:HumansCells
  17. Legendre M, Pochet N, Pak T, Verstrepen KJ. Sequence-based estimation of minisatellite and microsatellite repeat variability. Genome Res. 2007 Dec; 17(12):1787-96. PMID: 17978285.
    Citations: 100     Fields:    Translation:HumansAnimalsCells
  18. Camillone N, Pak TR, Adib K, Osgood RM. Tuning molecule-surface interactions with sub-nanometer-thick covalently bound organic monolayers. J Phys Chem B. 2006 Jun 15; 110(23):11334-43. PMID: 16771404.
    Citations:    Fields:    
  19. Pak T, Cadet P, Mantione KJ, Stefano GB. Morphine via nitric oxide modulates beta-amyloid metabolism: a novel protective mechanism for Alzheimer's disease. Med Sci Monit. 2005 Oct; 11(10):BR357-66. PMID: 16192893.
    Citations: 17     Fields:    Translation:HumansCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.