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profileLior Mayo, Ph.D.

TitleResearch Fellow in Neurology (EXT)
InstitutionBrigham and Women's Hospital
DepartmentNeurology
AddressHarvard Institutes of Medicine
BWH/Neurology - 7th Floor
77 Avenue Louis Pasteur
Boston MA 02115
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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Ito Y, Ofengeim D, Najafov A, Das S, Saberi S, Li Y, Hitomi J, Zhu H, Chen H, Mayo L, Geng J, Amin P, DeWitt JP, Mookhtiar AK, Florez M, Ouchida AT, Fan JB, Pasparakis M, Kelliher MA, Ravits J, Yuan J. RIPK1 mediates axonal degeneration by promoting inflammation and necroptosis in ALS. Science. 2016 Aug 05; 353(6299):603-8. PMID: 27493188.
    View in: PubMed
  2. Mayo L, Cunha AP, Madi A, Beynon V, Yang Z, Alvarez JI, Prat A, Sobel RA, Kobzik L, Lassmann H, Quintana FJ, Weiner HL. IL-10-dependent Tr1 cells attenuate astrocyte activation and ameliorate chronic central nervous system inflammation. Brain. 2016 Jul; 139(Pt 7):1939-57. PMID: 27246324; PMCID: PMC4939696.
  3. Rothhammer V, Mascanfroni ID, Bunse L, Takenaka MC, Kenison JE, Mayo L, Chao CC, Patel B, Yan R, Blain M, Alvarez JI, Kébir H, Anandasabapathy N, Izquierdo G, Jung S, Obholzer N, Pochet N, Clish CB, Prinz M, Prat A, Antel J, Quintana FJ. Type I interferons and microbial metabolites of tryptophan modulate astrocyte activity and central nervous system inflammation via the aryl hydrocarbon receptor. Nat Med. 2016 Jun; 22(6):586-97. PMID: 27158906; PMCID: PMC4899206 [Available on 11/09/16].
  4. Mayo L, Trauger SA, Blain M, Nadeau M, Patel B, Alvarez JI, Mascanfroni ID, Yeste A, Kivisäkk P, Kallas K, Ellezam B, Bakshi R, Prat A, Antel JP, Weiner HL, Quintana FJ. Regulation of astrocyte activation by glycolipids drives chronic CNS inflammation. Nat Med. 2014 Oct; 20(10):1147-56. PMID: 25216636; PMCID: PMC4255949.
  5. Mascanfroni ID, Yeste A, Vieira SM, Burns EJ, Patel B, Sloma I, Wu Y, Mayo L, Ben-Hamo R, Efroni S, Kuchroo VK, Robson SC, Quintana FJ. IL-27 acts on DCs to suppress the T cell response and autoimmunity by inducing expression of the immunoregulatory molecule CD39. Nat Immunol. 2013 Oct; 14(10):1054-63. PMID: 23995234; PMCID: PMC3964005.
  6. Koeglsperger T, Li S, Brenneis C, Saulnier JL, Mayo L, Carrier Y, Selkoe DJ, Weiner HL. Impaired glutamate recycling and GluN2B-mediated neuronal calcium overload in mice lacking TGF-ß1 in the CNS. Glia. 2013 Jun; 61(6):985-1002. PMID: 23536313; PMCID: PMC3981075.
  7. Mayo L, Quintana FJ, Weiner HL. The innate immune system in demyelinating disease. Immunol Rev. 2012 Jul; 248(1):170-87. PMID: 22725961; PMCID: PMC3383669.
  8. Levy A, Blacher E, Vaknine H, Lund FE, Stein R, Mayo L. CD38 deficiency in the tumor microenvironment attenuates glioma progression and modulates features of tumor-associated microglia/macrophages. Neuro Oncol. 2012 Aug; 14(8):1037-49. PMID: 22700727; PMCID: PMC3408254.
  9. Mayo L, Levy A, Jacob-Hirsch J, Amariglio N, Rechavi G, Stein R. Bid regulates the immunological profile of murine microglia and macrophages. Glia. 2011 Mar; 59(3):397-412. PMID: 21264947.
    View in: PubMed
  10. Levy A, Bercovich-Kinori A, Alexandrovich AG, Tsenter J, Trembovler V, Lund FE, Shohami E, Stein R, Mayo L. CD38 facilitates recovery from traumatic brain injury. J Neurotrauma. 2009 Sep; 26(9):1521-33. PMID: 19257806; PMCID: PMC2864472.
  11. Mayo L, Jacob-Hirsch J, Amariglio N, Rechavi G, Moutin MJ, Lund FE, Stein R. Dual role of CD38 in microglial activation and activation-induced cell death. J Immunol. 2008 Jul 01; 181(1):92-103. PMID: 18566373; PMCID: PMC3683558.
  12. Mayo L, Stein R. Characterization of LPS and interferon-gamma triggered activation-induced cell death in N9 and primary microglial cells: induction of the mitochondrial gateway by nitric oxide. Cell Death Differ. 2007 Jan; 14(1):183-6. PMID: 16778833.
    View in: PubMed
  13. Rothem L, Stark M, Kaufman Y, Mayo L, Assaraf YG. Reduced folate carrier gene silencing in multiple antifolate-resistant tumor cell lines is due to a simultaneous loss of function of multiple transcription factors but not promoter methylation. J Biol Chem. 2004 Jan 02; 279(1):374-84. PMID: 14551190.
    View in: PubMed
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