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Hetal Shah, M.B.,B.S.

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Biography
2021
Young Investigator Award (ADA)
2008 - 2010
Merit Award (BUSPH)
2008 - 2010
Scholarship (BUSPH)

Overview

Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. 2 P30 DK036836-36 (SHAH, HETAL) May 1, 2022 - Apr 30, 2024
    NIH/NIDDK/Joslin DRC P&F
    Evaluating early biomarkers and factors related to cognitive decline and Alzheimer's dementia in middle-aged adults with long duration type 1 diabetes
    Role: Principal Investigator
  2. 1R01HL161864-01 (KING, GEORGE L) Dec 1, 2021 - Nov 30, 2026
    NIH/NHLBI
    Characterization of cardiovascular diseases (CVD) in people with long duration Type 1 diabetes
    Role: Co-Investigator
  3. R21HL153559 (DORIA, ALESSANDRO) Aug 1, 2020 - Jul 31, 2022
    NIH
    Genotype-dependent cardiovascular and anti-inflammatory effects of fenofibrate
    Role: Co-Investigator
  4. 3P30DK036836-34S2 (SHAH, HETAL) Jul 9, 2020 - Mar 31, 2022
    NIH/NIDDK
    Characterization of cognitive decline and Alzheimer's disease in long duration Type 1 diabetes
    Role: Principal Investigator
  5. DP3DK112192 (KING, GEORGE L) Sep 30, 2016 - Sep 29, 2019
    NIH
    Pyruvate kinase M2 levels and activation as protective factors for diabetic nephropathy
    Role: Co-Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Shah HS, Moreno LO, Morieri ML, Tang Y, Mendonca C, Jobe JM, Thacker JB, Mitri J, Monti S, Niewczas MA, Pennathur S, Doria A. Serum Orotidine: A Novel Biomarker of Increased CVD Risk in Type 2 Diabetes Discovered Through Metabolomics Studies. Diabetes Care. 2022 08 01; 45(8):1882-1892. PMID: 35696261; PMCID: PMC9346986.
    Citations:    Fields:    
  2. Park K, Li Q, Lynes MD, Yokomizo H, Maddaloni E, Shinjo T, St-Louis R, Li Q, Katagiri S, Fu J, Clermont A, Park H, Wu IH, Yu MG, Shah H, Tseng YH, King GL. Endothelial Cells Induced Progenitors Into Brown Fat to Reduce Atherosclerosis. Circ Res. 2022 07 08; 131(2):168-183. PMID: 35642564; PMCID: PMC9308716.
    Citations:    Fields:    Translation:AnimalsCells
  3. Bahour N, Cortez B, Pan H, Shah H, Doria A, Aguayo-Mazzucato C. Diabetes mellitus correlates with increased biological age as indicated by clinical biomarkers. Geroscience. 2022 02; 44(1):415-427. PMID: 34773197; PMCID: PMC8589453.
    Citations: 3     Fields:    Translation:Humans
  4. Fickweiler W, Wolfson EA, Paniagua SM, Yu MG, Adam A, Bahnam V, Sampani K, Wu IH, Musen G, Aiello LP, Shah H, Sun JK, King GL. Response to Letter to the Editor from Brunerova et al: "Association of Cognitive Function and Retinal Neural and Vascular Structure in Type 1 Diabetes". J Clin Endocrinol Metab. 2021 08 18; 106(9):e3789-e3790. PMID: 34038552; PMCID: PMC8372663.
    Citations:    Fields:    Translation:Humans
  5. Mariam A, Miller-Atkins G, Pantalone KM, Zimmerman RS, Barnard J, Kattan MW, Shah H, McLeod HL, Doria A, Wagner MJ, Buse JB, Motsinger-Reif AA, Rotroff DM. A Type 2 Diabetes Subtype Responsive to ACCORD Intensive Glycemia Treatment. Diabetes Care. 2021 06; 44(6):1410-1418. PMID: 33863751; PMCID: PMC8247498.
    Citations: 1     Fields:    Translation:Humans
  6. Fickweiler W, Wolfson EA, Paniagua SM, Yu MG, Adam A, Bahnam V, Sampani K, Wu IH, Musen G, Aiello LP, Shah H, Sun JK, King GL. Association of Cognitive Function and Retinal Neural and Vascular Structure in Type 1 Diabetes. J Clin Endocrinol Metab. 2021 03 25; 106(4):1139-1149. PMID: 33378459; PMCID: PMC7993575.
    Citations: 4     Fields:    Translation:HumansCells
  7. Tang Y, Shah H, Bueno Junior CR, Sun X, Mitri J, Sambataro M, Sambado L, Gerstein HC, Fonseca V, Doria A, Pop-Busui R. Intensive Risk Factor Management and Cardiovascular Autonomic Neuropathy in Type 2 Diabetes: The ACCORD Trial. Diabetes Care. 2021 01; 44(1):164-173. PMID: 33144354; PMCID: PMC7783932.
    Citations: 6     Fields:    Translation:Humans
  8. Pipino C, Shah H, Prudente S, Di Pietro N, Zeng L, Park K, Trischitta V, Pennathur S, Pandolfi A, Doria A. Association of the 1q25 Diabetes-Specific Coronary Heart Disease Locus With Alterations of the ?-Glutamyl Cycle and Increased Methylglyoxal Levels in Endothelial Cells. Diabetes. 2020 10; 69(10):2206-2216. PMID: 32651240; PMCID: PMC7506838.
    Citations: 3     Fields:    Translation:HumansCells
  9. Morieri ML, Shah HS, Tang Y, Doria A. Insufficient Evidence for Interaction Between Haptoglobin Phenotypes and Intensive Glycemic Control on Cardiovascular Outcomes. J Am Coll Cardiol. 2020 06 16; 75(23):2995-2996. PMID: 32527409.
    Citations:    Fields:    Translation:Humans
  10. Morieri ML, Shah HS, Sjaarda J, Lenzini PA, Campbell H, Motsinger-Reif AA, Gao H, Lovato L, Prudente S, Pandolfi A, Pezzolesi MG, Sigal RJ, Paré G, Marcovina SM, Rotroff DM, Patorno E, Mercuri L, Trischitta V, Chew EY, Kraft P, Buse JB, Wagner MJ, Cresci S, Gerstein HC, Ginsberg HN, Mychaleckyj JC, Doria A. PPARA Polymorphism Influences the Cardiovascular Benefit of Fenofibrate in Type 2 Diabetes: Findings From ACCORD-Lipid. Diabetes. 2020 04; 69(4):771-783. PMID: 31974142; PMCID: PMC7085251.
    Citations: 11     Fields:    Translation:Humans
  11. Amo Usanos C, Valenzuela PL, de la Villa P, Navarro SM, Melo Aroeira AE, Amo Usanos I, Martínez Cancio L, Cuesta Villa L, Shah H, Magerowski G, Alonso-Alonso M. Neuromodulation of the prefrontal cortex facilitates diet-induced weight loss in midlife women: a randomized, proof-of-concept clinical trial. Int J Obes (Lond). 2020 03; 44(3):568-578. PMID: 31740726.
    Citations: 3     Fields:    Translation:Humans
  12. Vaisar T, Kanter JE, Wimberger J, Irwin AD, Gauthier J, Wolfson E, Bahnam V, Wu IH, Shah H, Keenan HA, Greenbaum CJ, King GL, Heinecke JW, Bornfeldt KE. High Concentration of Medium-Sized HDL Particles and Enrichment in HDL Paraoxonase 1 Associate With Protection From Vascular Complications in People With Long-standing Type 1 Diabetes. Diabetes Care. 2020 01; 43(1):178-186. PMID: 31597668.
    Citations: 14     Fields:    Translation:Humans
  13. Copetti M, Shah H, Fontana A, Scarale MG, Menzaghi C, De Cosmo S, Garofolo M, Sorrentino MR, Lamacchia O, Penno G, Doria A, Trischitta V. Estimation of Mortality Risk in Type 2 Diabetic Patients (ENFORCE): An Inexpensive and Parsimonious Prediction Model. J Clin Endocrinol Metab. 2019 10 01; 104(10):4900-4908. PMID: 31087060; PMCID: PMC6734484.
    Citations: 5     Fields:    Translation:Humans
  14. Yu MG, Keenan HA, Shah HS, Frodsham SG, Pober D, He Z, Wolfson EA, D'Eon S, Tinsley LJ, Bonner-Weir S, Pezzolesi MG, King GL. Residual ß cell function and monogenic variants in long-duration type 1 diabetes patients. J Clin Invest. 2019 07 02; 129(8):3252-3263. PMID: 31264968; PMCID: PMC6668678.
    Citations: 29     Fields:    Translation:HumansCellsCTClinical Trials
  15. Tang Y, Lenzini PA, Pop-Busui R, Ray PR, Campbell H, Perkins BA, Callaghan B, Wagner MJ, Motsinger-Reif AA, Buse JB, Price TJ, Mychaleckyj JC, Cresci S, Shah H, Doria A. A Genetic Locus on Chromosome 2q24 Predicting Peripheral Neuropathy Risk in Type 2 Diabetes: Results From the ACCORD and BARI 2D Studies. Diabetes. 2019 08; 68(8):1649-1662. PMID: 31127053; PMCID: PMC6692816.
    Citations: 5     Fields:    Translation:HumansCells
  16. Shinjo T, Ishikado A, Hasturk H, Pober DM, Paniagua SM, Shah H, Wu IH, Tinsley LJ, Matsumoto M, Keenan HA, Van Dyke TE, Genco RJ, King GL. Characterization of periodontitis in people with type 1 diabetes of 50 years or longer duration. J Periodontol. 2019 06; 90(6):565-575. PMID: 31026349; PMCID: PMC7087383.
    Citations: 3     Fields:    Translation:HumansPHPublic Health
  17. Gordin D, Shah H, Shinjo T, St-Louis R, Qi W, Park K, Paniagua SM, Pober DM, Wu IH, Bahnam V, Brissett MJ, Tinsley LJ, Dreyfuss JM, Pan H, Dong Y, Niewczas MA, Amenta P, Sadowski T, Kannt A, Keenan HA, King GL. Characterization of Glycolytic Enzymes and Pyruvate Kinase M2 in Type 1 and 2 Diabetic Nephropathy. Diabetes Care. 2019 07; 42(7):1263-1273. PMID: 31076418.
    Citations: 28     Fields:    Translation:HumansCells
  18. Niewczas MA, Pavkov ME, Skupien J, Smiles A, Md Dom ZI, Wilson JM, Park J, Nair V, Schlafly A, Saulnier PJ, Satake E, Simeone CA, Shah H, Qiu C, Looker HC, Fiorina P, Ware CF, Sun JK, Doria A, Kretzler M, Susztak K, Duffin KL, Nelson RG, Krolewski AS. A signature of circulating inflammatory proteins and development of end-stage renal disease in diabetes. Nat Med. 2019 05; 25(5):805-813. PMID: 31011203.
    Citations: 101     Fields:    Translation:Humans
  19. Morieri ML, Gao H, Pigeyre M, Shah HS, Sjaarda J, Mendonca C, Hastings T, Buranasupkajorn P, Motsinger-Reif AA, Rotroff DM, Sigal RJ, Marcovina SM, Kraft P, Buse JB, Wagner MJ, Gerstein HC, Mychaleckyj JC, Parè G, Doria A. Genetic Tools for Coronary Risk Assessment in Type 2 Diabetes: A Cohort Study From the ACCORD Clinical Trial. Diabetes Care. 2018 Nov; 41(11):2404-2413. PMID: 30262460.
    Citations: 10     Fields:    Translation:Humans
  20. Rotroff DM, Yee SW, Zhou K, Marvel SW, Shah HS, Jack JR, Havener TM, Hedderson MM, Kubo M, Herman MA, Gao H, Mychaleckyi JC, McLeod HL, Doria A, Giacomini KM, Pearson ER, Wagner MJ, Buse JB, Motsinger-Reif AA. Genetic Variants in CPA6 and PRPF31 Are Associated With Variation in Response to Metformin in Individuals With Type 2 Diabetes. Diabetes. 2018 07; 67(7):1428-1440. PMID: 29650774; PMCID: PMC6014560.
    Citations: 14     Fields:    Translation:Humans
  21. Shah HS, Morieri ML, Marcovina SM, Sigal RJ, Gerstein HC, Wagner MJ, Motsinger-Reif AA, Buse JB, Kraft P, Mychaleckyj JC, Doria A. Modulation of GLP-1 Levels by a Genetic Variant That Regulates the Cardiovascular Effects of Intensive Glycemic Control in ACCORD. Diabetes Care. 2018 02; 41(2):348-355. PMID: 29183908.
    Citations: 7     Fields:    Translation:Humans
  22. Rotroff DM, Pijut SS, Marvel SW, Jack JR, Havener TM, Pujol A, Schluter A, Graf GA, Ginsberg HN, Shah HS, Gao H, Morieri ML, Doria A, Mychaleckyi JC, McLeod HL, Buse JB, Wagner MJ, Motsinger-Reif AA. Genetic Variants in HSD17B3, SMAD3, and IPO11 Impact Circulating Lipids in Response to Fenofibrate in Individuals With Type 2 Diabetes. Clin Pharmacol Ther. 2018 04; 103(4):712-721. PMID: 28736931; PMCID: PMC5828950.
    Citations: 15     Fields:    Translation:HumansAnimalsCells
  23. Morieri ML, Shah HS, Lovato L, Mychaleckyj JC, Ginsberg HN, Doria A. Increase in apoliporotein-A2 Levels is associated with lower cardiovascular risk in the accord lipid trial. Atherosclerosis. 2017 Aug; 263:e43. PMID: 29366108.
    Citations:    Fields:    
  24. Morieri ML, Shah H, Doria A. Variants in ANGPTL4 and the Risk of Coronary Artery Disease. N Engl J Med. 2016 12 08; 375(23):2304-2305. PMID: 28112899.
    Citations: 5     Fields:    
  25. Shah HS, Gao H, Morieri ML, Skupien J, Marvel S, Paré G, Mannino GC, Buranasupkajorn P, Mendonca C, Hastings T, Marcovina SM, Sigal RJ, Gerstein HC, Wagner MJ, Motsinger-Reif AA, Buse JB, Kraft P, Mychaleckyj JC, Doria A. Genetic Predictors of Cardiovascular Mortality During Intensive Glycemic Control in Type 2 Diabetes: Findings From the ACCORD Clinical Trial. Diabetes Care. 2016 Nov; 39(11):1915-1924. PMID: 27527847; PMCID: PMC5079609.
    Citations: 13     Fields:    Translation:Humans
  26. Prudente S, Shah H, Bailetti D, Pezzolesi M, Buranasupkajorn P, Mercuri L, Mendonca C, De Cosmo S, Niewczas M, Trischitta V, Doria A. Genetic Variant at the GLUL Locus Predicts All-Cause Mortality in Patients With Type 2 Diabetes. Diabetes. 2015 Jul; 64(7):2658-63. PMID: 25677913; PMCID: PMC4477355.
    Citations: 15     Fields:    Translation:Humans
  27. Prudente S, Morini E, Marselli L, Baratta R, Copetti M, Mendonca C, Andreozzi F, Chandalia M, Pellegrini F, Bailetti D, Alberico F, Shah H, Abate N, Sesti G, Frittitta L, Marchetti P, Doria A, Trischitta V. Joint effect of insulin signaling genes on insulin secretion and glucose homeostasis. J Clin Endocrinol Metab. 2013 Jun; 98(6):E1143-7. PMID: 23633196; PMCID: PMC6618023.
    Citations: 9     Fields:    Translation:HumansCells
  28. De Cosmo S, Prudente S, Lamacchia O, Lucchesi D, Shah H, Mendonca C, Pucci L, Mercuri L, Gervino EV, Hauser TH, Bailetti D, Penno G, Cignarelli M, Doria A, Trischitta V. The 9p21 coronary artery disease locus and kidney dysfunction in patients with Type 2 diabetes mellitus. Nephrol Dial Transplant. 2012 Dec; 27(12):4411-3. PMID: 22622453.
    Citations: 3     Fields:    Translation:HumansCells
  29. Sharma R, Prudente S, Andreozzi F, Powers C, Mannino G, Bacci S, Gervino EV, Hauser TH, Succurro E, Mercuri L, Goheen EH, Shah H, Trischitta V, Sesti G, Doria A. The type 2 diabetes and insulin-resistance locus near IRS1 is a determinant of HDL cholesterol and triglycerides levels among diabetic subjects. Atherosclerosis. 2011 May; 216(1):157-60. PMID: 21353221.
    Citations: 13     Fields:    Translation:Humans
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.