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Shahrokh Charles Khani, Ph.D., M.D.


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  1. R01EY013600 (KHANI, SHAHROKH C) Aug 1, 2003 - Jul 31, 2009
    Transcriptional Regulation of Rhodopsin Kinase Gene
    Role: Principal Investigator

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Sakurai K, Chen J, Khani SC, Kefalov VJ. Regulation of mammalian cone phototransduction by recoverin and rhodopsin kinase. J Biol Chem. 2015 Apr 03; 290(14):9239-50. PMID: 25673692.
    Citations: 15     Fields:    Translation:AnimalsCells
  2. Sakurai K, Young JE, Kefalov VJ, Khani SC. Variation in rhodopsin kinase expression alters the dim flash response shut off and the light adaptation in rod photoreceptors. Invest Ophthalmol Vis Sci. 2011 Aug 29; 52(9):6793-800. PMID: 21474765.
    Citations: 10     Fields:    Translation:AnimalsCells
  3. Pawlyk BS, Bulgakov OV, Liu X, Xu X, Adamian M, Sun X, Khani SC, Berson EL, Sandberg MA, Li T. Replacement gene therapy with a human RPGRIP1 sequence slows photoreceptor degeneration in a murine model of Leber congenital amaurosis. Hum Gene Ther. 2010 Aug; 21(8):993-1004. PMID: 20384479.
    Citations: 39     Fields:    Translation:HumansAnimalsCells
  4. Semple-Rowland SL, Coggin WE, Geesey M, Eccles KS, Abraham L, Pachigar K, Ludlow R, Khani SC, Smith WC. Expression characteristics of dual-promoter lentiviral vectors targeting retinal photoreceptors and Müller cells. Mol Vis. 2010 May 27; 16:916-34. PMID: 20517486.
    Citations: 9     Fields:    Translation:AnimalsCells
  5. Whitcomb T, Sakurai K, Brown BM, Young JE, Sheflin L, Dlugos C, Craft CM, Kefalov VJ, Khani SC. Effect of g protein-coupled receptor kinase 1 (Grk1) overexpression on rod photoreceptor cell viability. Invest Ophthalmol Vis Sci. 2010 Mar; 51(3):1728-37. PMID: 19834036.
    Citations: 8     Fields:    Translation:AnimalsCellsPHPublic Health
  6. Khani SC, Pawlyk BS, Bulgakov OV, Kasperek E, Young JE, Adamian M, Sun X, Smith AJ, Ali RR, Li T. AAV-mediated expression targeting of rod and cone photoreceptors with a human rhodopsin kinase promoter. Invest Ophthalmol Vis Sci. 2007 Sep; 48(9):3954-61. PMID: 17724172.
    Citations: 56     Fields:    Translation:AnimalsCells
  7. Young JE, Kasperek EM, Vogt TM, Lis A, Khani SC. Conserved interactions of a compact highly active enhancer/promoter upstream of the rhodopsin kinase (GRK1) gene. Genomics. 2007 Aug; 90(2):236-48. PMID: 17524610.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  8. Young JE, Gross KW, Khani SC. Conserved structure and spatiotemporal function of the compact rhodopsin kinase (GRK1) enhancer/promoter. Mol Vis. 2005 Dec 07; 11:1041-51. PMID: 16357827.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  9. Young JE, Vogt T, Gross KW, Khani SC. A short, highly active photoreceptor-specific enhancer/promoter region upstream of the human rhodopsin kinase gene. Invest Ophthalmol Vis Sci. 2003 Sep; 44(9):4076-85. PMID: 12939331.
    Citations: 20     Fields:    Translation:HumansAnimalsCells
  10. Khani SC, Karoukis AJ, Young JE, Ambasudhan R, Burch T, Stockton R, Lewis RA, Sullivan LS, Daiger SP, Reichel E, Ayyagari R. Late-onset autosomal dominant macular dystrophy with choroidal neovascularization and nonexudative maculopathy associated with mutation in the RDS gene. Invest Ophthalmol Vis Sci. 2003 Aug; 44(8):3570-7. PMID: 12882809.
    Citations: 10     Fields:    Translation:HumansCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.