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Khalid Hanafy, Ph.D., M.D.

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Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01NS109174 (HANAFY, KHALID A.) Dec 15, 2018 - Nov 30, 2023
    NIH/NINDS
    Modulation of the TLR4-Lyn interaction in SAH
    Role: Principal Investigator
  2. R21NS099606 (HANAFY, KHALID A.) Jun 15, 2017 - May 31, 2019
    NIH/NINDS
    The role of TLR4-dependent sterile inflammation in mediating adverse outcomes after SAH
    Role: Principal Investigator
  3. K08NS078048 (HANAFY, KHALID A.) Sep 30, 2012 - Jun 30, 2017
    NIH/NINDS
    Microglial Signal Transduction in Fever and Vasospasm after Subarachnoid Hemorrha
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Hanafy KA, Gomes JA, Selim M. Rationale and Current Evidence for Testing Iron Chelators for Treating Stroke. Curr Cardiol Rep. 2019 Mar 04; 21(4):20. PMID: 30828740.
    Citations:    
  2. Hedblom A, Hejazi SM, Canesin G, Choudhury R, Hanafy KA, Csizmadia E, Persson JL, Wegiel B. Heme detoxification by heme oxygenase-1 reinstates proliferative and immune balances upon genotoxic tissue injury. Cell Death Dis. 2019 Jan 25; 10(2):72. PMID: 30683864.
    Citations:    Fields:    
  3. Thomas AJ, Ogilvy CS, Griessenauer CJ, Hanafy KA. Macrophage CD163 expression in cerebrospinal fluid: association with subarachnoid hemorrhage outcome. J Neurosurg. 2018 Jul 01; 1-7. PMID: 30028262.
    Citations:    Fields:    
  4. Griessenauer CJ, Chua MH, Hanafy KA, Baffour YT, Chen R, LeBlanc RH, Patel AS, Salem M, Karumanchi SA, Xu D, Thadhani R, Ogilvy CS, Thomas AJ. Soluble Fms-Like Tyrosine Kinase 1 (sFlt-1) and Risk of Cerebral Vasospasm After Aneurysmal Subarachnoid Hemorrhage. World Neurosurg. 2017 Dec; 108:84-89. PMID: 28867315.
    Citations:    Fields:    Translation:Humans
  5. Schallner N, Lieberum JL, Gallo D, LeBlanc RH, Fuller PM, Hanafy KA, Otterbein LE. Carbon Monoxide Preserves Circadian Rhythm to Reduce the Severity of Subarachnoid Hemorrhage in Mice. Stroke. 2017 09; 48(9):2565-2573. PMID: 28747460.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  6. Boone MD, Jinadasa SP, Mueller A, Shaefi S, Kasper EM, Hanafy KA, O'Gara BP, Talmor DS. The Effect of Positive End-Expiratory Pressure on Intracranial Pressure and Cerebral Hemodynamics. Neurocrit Care. 2017 04; 26(2):174-181. PMID: 27848125.
    Citations: 3     Fields:    Translation:Humans
  7. LeBlanc RH, Chen R, Selim MH, Hanafy KA. Heme oxygenase-1-mediated neuroprotection in subarachnoid hemorrhage via intracerebroventricular deferoxamine. J Neuroinflammation. 2016 09 13; 13(1):244. PMID: 27618864.
    Citations: 2     Fields:    Translation:AnimalsCells
  8. Lioutas VA, Hanafy KA, Kumar S. Predictors of extubation success in acute ischemic stroke patients. J Neurol Sci. 2016 Sep 15; 368:191-4. PMID: 27538631.
    Citations: 1     Fields:    Translation:Humans
  9. Schallner N, Pandit R, LeBlanc R, Thomas AJ, Ogilvy CS, Zuckerbraun BS, Gallo D, Otterbein LE, Hanafy KA. Microglia regulate blood clearance in subarachnoid hemorrhage by heme oxygenase-1. J Clin Invest. 2015 Jul 01; 125(7):2609-25. PMID: 26011640.
    Citations: 28     Fields:    Translation:HumansAnimalsCells
  10. Schomer AC, Hanafy K. Neuromonitoring in the ICU. Int Anesthesiol Clin. 2015; 53(1):107-22. PMID: 25551745.
    Citations: 1     Fields:    Translation:Humans
  11. Kurtz P, Claassen J, Schmidt JM, Helbok R, Hanafy KA, Presciutti M, Lantigua H, Connolly ES, Lee K, Badjatia N, Mayer SA. Reduced brain/serum glucose ratios predict cerebral metabolic distress and mortality after severe brain injury. Neurocrit Care. 2013 Dec; 19(3):311-9. PMID: 24081837.
    Citations: 7     Fields:    Translation:Humans
  12. Hanafy KA. The role of microglia and the TLR4 pathway in neuronal apoptosis and vasospasm after subarachnoid hemorrhage. J Neuroinflammation. 2013 Jul 13; 10:83. PMID: 23849248.
    Citations: 36     Fields:    Translation:AnimalsCells
  13. Krishnan V, Tarula E, Anderson MP, Hanafy KA, Herman ST. Postictal bradyarrhythmia following an isolated seizure in a patient with left hemisphere stroke. Seizure. 2013 Dec; 22(10):908-10. PMID: 23849848.
    Citations:    Fields:    Translation:Humans
  14. Hanafy KA, Oh J, Otterbein LE. Carbon Monoxide and the brain: time to rethink the dogma. Curr Pharm Des. 2013; 19(15):2771-5. PMID: 23092321.
    Citations: 10     Fields:    Translation:Humans
  15. Hanafy KA, Selim MH. Antioxidant strategies in neurocritical care. Neurotherapeutics. 2012 Jan; 9(1):44-55. PMID: 22135010.
    Citations: 5     Fields:    Translation:Humans
  16. Hanafy KA, Sloane JA. Regulation of remyelination in multiple sclerosis. FEBS Lett. 2011 Dec 01; 585(23):3821-8. PMID: 21443876.
    Citations: 14     Fields:    Translation:HumansAnimalsCells
  17. Helbok R, Schmidt JM, Kurtz P, Hanafy KA, Fernandez L, Stuart RM, Presciutti M, Ostapkovich ND, Connolly ES, Lee K, Badjatia N, Mayer SA, Claassen J. Systemic glucose and brain energy metabolism after subarachnoid hemorrhage. Neurocrit Care. 2010 Jun; 12(3):317-23. PMID: 20135362.
    Citations: 24     Fields:    Translation:Humans
  18. Hanafy KA, Stuart RM, Khandji AG, Connolly ES, Badjatia N, Mayer SA, Schindler C. Relationship between brain interstitial fluid tumor necrosis factor-a and cerebral vasospasm after aneurysmal subarachnoid hemorrhage. J Clin Neurosci. 2010 Jul; 17(7):853-6. PMID: 20471835.
    Citations: 8     Fields:    Translation:HumansCells
  19. Hanafy KA, Grobelny B, Fernandez L, Kurtz P, Connolly ES, Mayer SA, Schindler C, Badjatia N. Brain interstitial fluid TNF-alpha after subarachnoid hemorrhage. J Neurol Sci. 2010 Apr 15; 291(1-2):69-73. PMID: 20110094.
    Citations: 18     Fields:    Translation:HumansCells
  20. Hanafy KA, Morgan Stuart R, Fernandez L, Schmidt JM, Claassen J, Lee K, Sander Connolly E, Mayer SA, Badjatia N. Cerebral inflammatory response and predictors of admission clinical grade after aneurysmal subarachnoid hemorrhage. J Clin Neurosci. 2010 Jan; 17(1):22-5. PMID: 20004102.
    Citations: 9     Fields:    Translation:Humans
  21. Kurtz P, Hanafy KA, Claassen J. Continuous EEG monitoring: is it ready for prime time? Curr Opin Crit Care. 2009 Apr; 15(2):99-109. PMID: 19578320.
    Citations: 11     Fields:    Translation:Humans
  22. Hanafy KA, Martin E, Murad F. CCTeta, a novel soluble guanylyl cyclase-interacting protein. J Biol Chem. 2004 Nov 05; 279(45):46946-53. PMID: 15347653.
    Citations: 15     Fields:    Translation:AnimalsCells
  23. Krumenacker JS, Hanafy KA, Murad F. Regulation of nitric oxide and soluble guanylyl cyclase. Brain Res Bull. 2004 Feb 15; 62(6):505-15. PMID: 15036565.
    Citations: 39     Fields:    Translation:HumansAnimals
  24. Hanafy KA, Krumenacker JS, Murad F. NO, nitrotyrosine, and cyclic GMP in signal transduction. Med Sci Monit. 2001 Jul-Aug; 7(4):801-19. PMID: 11433215.
    Citations: 45     Fields:    Translation:HumansAnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.