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Henry Lee, M.Phil.

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UCL, LondonPhD05/2009Neuroscience
HKUST, Hong KongMPhil2003Neuroscience
Young Investigator Award
Research Program Grant
2010 - 2012
Croucher Foundation post-doctoral fellowship
2009 - 2010
Founder's Affiliate AHA post-doctoral fellowship
- 2009
Doctor of Philosophy (Neuroscience, Physiology and Pharmacology)
2007 - 2008
AES pre-doctoral research training fellowship
- 2003
Master of Philosophy (Molecular Neurobiology)
- 2001
First Class Honors, Bachelor of Science (Biochemistry)
2000 - 2001
Sir Edward Youde Memorial Scholarship
1999 - 2000
The George K Lee Foundation Scholarship
1998 - 1999
Wu Ti Hsien Science and Education Foundation Fund Scholarship
- 1998
Distinction (A) in Chemistry, Biology; Merits (B) in Physics in Hong Kong Advanced Level Examination
- 1996
Flute, practical examination (Grade 8)
1990 - 1991
KCOBA Jubilee Memorial Scholarship


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Lee HHC, McGinty GE, Pearl PL, Rotenberg A. Understanding the Molecular Mechanisms of Succinic Semialdehyde Dehydrogenase Deficiency (SSADHD): Towards the Development of SSADH-Targeted Medicine. Int J Mol Sci. 2022 Feb 26; 23(5). PMID: 35269750; PMCID: PMC8910003.
    Citations:    Fields:    Translation:HumansAnimals
  2. Lee HHC, Pearl PL, Rotenberg A. Enzyme Replacement Therapy for Succinic Semialdehyde Dehydrogenase Deficiency: Relevance in ?-Aminobutyric Acid Plasticity. J Child Neurol. 2021 11; 36(13-14):1200-1209. PMID: 33624531; PMCID: PMC8382780.
    Citations: 1     Fields:    Translation:Animals
  3. MacMullin P, Hodgson N, Damar U, Lee HHC, Hameed MQ, Dhamne SC, Hyde D, Conley GM, Morriss N, Qiu J, Mannix R, Hensch TK, Rotenberg A. Increase in Seizure Susceptibility After Repetitive Concussion Results from Oxidative Stress, Parvalbumin-Positive Interneuron Dysfunction and Biphasic Increases in Glutamate/GABA Ratio. Cereb Cortex. 2020 11 03; 30(12):6108-6120. PMID: 32676666.
    Citations: 4     Fields:    Translation:AnimalsCells
  4. Hameed MQ, Hsieh TH, Morales-Quezada L, Lee HHC, Damar U, MacMullin PC, Hensch TK, Rotenberg A. Ceftriaxone Treatment Preserves Cortical Inhibitory Interneuron Function via Transient Salvage of GLT-1 in a Rat Traumatic Brain Injury Model. Cereb Cortex. 2019 12 17; 29(11):4506-4518. PMID: 30590449.
    Citations: 10     Fields:    Translation:AnimalsCells
  5. Hsieh TH, Lee HHC, Hameed MQ, Pascual-Leone A, Hensch TK, Rotenberg A. Trajectory of Parvalbumin Cell Impairment and Loss of Cortical Inhibition in Traumatic Brain Injury. Cereb Cortex. 2017 12 01; 27(12):5509-5524. PMID: 27909008; PMCID: PMC6075565.
    Citations: 35     Fields:    Translation:AnimalsCells
  6. Lee HHC, Bernard C, Ye Z, Acampora D, Simeone A, Prochiantz A, Di Nardo AA, Hensch TK. Genetic Otx2 mis-localization delays critical period plasticity across brain regions. Mol Psychiatry. 2017 05; 22(5):680-688. PMID: 28194008; PMCID: PMC5400722.
    Citations: 31     Fields:    Translation:AnimalsCells
  7. Bei F, Lee HHC, Liu X, Gunner G, Jin H, Ma L, Wang C, Hou L, Hensch TK, Frank E, Sanes JR, Chen C, Fagiolini M, He Z. Restoration of Visual Function by Enhancing Conduction in Regenerated Axons. Cell. 2016 Jan 14; 164(1-2):219-232. PMID: 26771493.
    Citations: 94     Fields:    Translation:AnimalsCells
  8. Silayeva L, Deeb TZ, Hines RM, Kelley MR, Munoz MB, Lee HH, Brandon NJ, Dunlop J, Maguire J, Davies PA, Moss SJ. KCC2 activity is critical in limiting the onset and severity of status epilepticus. Proc Natl Acad Sci U S A. 2015 Mar 17; 112(11):3523-8. PMID: 25733865; PMCID: PMC4371976.
    Citations: 59     Fields:    Translation:AnimalsCells
  9. Spatazza J, Lee HH, Di Nardo AA, Tibaldi L, Joliot A, Hensch TK, Prochiantz A. Choroid-plexus-derived Otx2 homeoprotein constrains adult cortical plasticity. Cell Rep. 2013 Jun 27; 3(6):1815-23. PMID: 23770240.
    Citations: 88     Fields:    Translation:HumansAnimals
  10. Beurdeley M, Spatazza J, Lee HH, Sugiyama S, Bernard C, Di Nardo AA, Hensch TK, Prochiantz A. Otx2 binding to perineuronal nets persistently regulates plasticity in the mature visual cortex. J Neurosci. 2012 Jul 04; 32(27):9429-37. PMID: 22764251.
    Citations: 166     Fields:    Translation:AnimalsCells
  11. Deeb TZ, Lee HH, Walker JA, Davies PA, Moss SJ. Hyperpolarizing GABAergic transmission depends on KCC2 function and membrane potential. Channels (Austin). 2011 Nov-Dec; 5(6):475-81. PMID: 22082832.
    Citations: 10     Fields:    Translation:HumansCells
  12. Lee HH, Deeb TZ, Walker JA, Davies PA, Moss SJ. NMDA receptor activity downregulates KCC2 resulting in depolarizing GABAA receptor-mediated currents. Nat Neurosci. 2011 Jun; 14(6):736-43. PMID: 21532577.
    Citations: 143     Fields:    Translation:AnimalsCells
  13. Lee HH, Jurd R, Moss SJ. Tyrosine phosphorylation regulates the membrane trafficking of the potassium chloride co-transporter KCC2. Mol Cell Neurosci. 2010 Oct; 45(2):173-9. PMID: 20600929.
    Citations: 79     Fields:    Translation:HumansAnimalsCells
  14. Lee HH, Walker JA, Williams JR, Goodier RJ, Payne JA, Moss SJ. Direct protein kinase C-dependent phosphorylation regulates the cell surface stability and activity of the potassium chloride cotransporter KCC2. J Biol Chem. 2007 Oct 12; 282(41):29777-84. PMID: 17693402.
    Citations: 137     Fields:    Translation:HumansCells
  15. Houston CM, Lee HH, Hosie AM, Moss SJ, Smart TG. Identification of the sites for CaMK-II-dependent phosphorylation of GABA(A) receptors. J Biol Chem. 2007 Jun 15; 282(24):17855-65. PMID: 17442679.
    Citations: 26     Fields:    Translation:HumansAnimalsCells
  16. Lee HH, Choi RC, Ting AK, Siow NL, Jiang JX, Massoulié J, Tsim KW. Transcriptional regulation of acetylcholinesterase-associated collagen ColQ: differential expression in fast and slow twitch muscle fibers is driven by distinct promoters. J Biol Chem. 2004 Jun 25; 279(26):27098-107. PMID: 15102835.
    Citations: 12     Fields:    Translation:HumansAnimalsCells
  17. Jiang JX, Choi RC, Siow NL, Lee HH, Wan DC, Tsim KW. Muscle induces neuronal expression of acetylcholinesterase in neuron-muscle co-culture: transcriptional regulation mediated by cAMP-dependent signaling. J Biol Chem. 2003 Nov 14; 278(46):45435-44. PMID: 12963741.
    Citations: 15     Fields:    Translation:HumansAnimalsCells
  18. Tsim KW, Choi RC, Siow NL, Cheng AW, Ling KK, Jiang JX, Tung EK, Lee HH, Xie QH, Simon J, Barnard EA. ATP induces post-synaptic gene expressions in vertebrate skeletal neuromuscular junctions. J Neurocytol. 2003 Jun-Sep; 32(5-8):603-17. PMID: 15034256.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.