Ranjna Sharma, M.D.
|Title||Assistant Professor of Surgery|
|Institution||Beth Israel Deaconess Medical Center|
|Address||Beth Israel Deaconess Medical Center|
BreastCare Center, Shapiro 5
330 Brookline Ave
Boston MA 02215
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|1994 - 1998||Ohio Academic Scholarship|
|1997||Psi Chi International Honor Society in Psychology|
|1997||Golden Key International Honor Society|
|1998||Alpha Phi Leadership Scholarship|
|2000 - 2002||College of Medicine Scholarship|
|2005||Resident Research Competition, 3rd place|
My clinical research interests include oncoplastic reconstruction of partial mastectomy defects, evaluating clinical outcomes in the octogenarian patient population diagnosed with invasive carcinoma, and identifying radiologic and pathologic features that contribute to an upgrade of common breast atypias to carcinoma. Our Group has developed a protocol to retrospectively study prospectively collected patient data examining the oncoplastic reconstruction of partial mastectomy defects. To date, approximately 10 patients have undergone oncoplastic reconstruction following lumpectomy under the direction of our Plastic Surgery colleagues. Our Group is developing a protocol to retrospectively study the treatment decisions and clinical outcomes in the octogenarian patient population, as compared to younger patients, diagnosed with early breast cancer. Our Group has also developed a Database to retrospectively review the upgrade rate from atypia to carcinoma in patients with atypical ductal hyperplasia (ADH), atypical lobular hyperplasia (ALH), and lobular carcinoma in situ (LCIS).
My translational research interests include breast cancer stem cell identification to elucidate diagnostic and therapeutic strategies, novel techniques to more accurately evaluate margins of surgical resection specimens, and evaluating the clinical efficacy of a breast cancer targeted vaccine.
I am also active in the education of surgical residents in the Department of Surgery at Beth Israel Deaconess Medical Center and Harvard Medical School students rotating on our surgical service as part of their third-year clerkship experience. I provide didactic lectures on the diagnosis and treatment of breast cancer. I have also developed our Service’s rotation-specific skills simulation curriculum and model, utilizing a gelatin breast model to teach principles of surgical resection during a wire-localized partial mastectomy.
Clinically, my practice involves the care of patients with benign and malignant breast disease. After completing a Fellowship in breast surgical oncology, this is my area of expertise. I perform advanced breast surgical oncology procedures to offer leading-edge care to our patient population.
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