Harvard Catalyst Profiles

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Elliot L. Chaikof, Ph.D., M.D.

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Biography
1976
Ann Shepard Biology Award, University College, University of Toronto
1977
Ann Shepard Zoology Award, University College, University of Toronto
1979
Phi Beta Kappa, Johns Hopkins University
1982
Alpha Omega Alpha, Johns Hopkins School of Medicine
1988
Sigma Xi, MIT
1996
E.J. Wylie Fellowship, Society for Vascular Surgery
1999
Distinguished Fellow, Society for Vascular Surgery
2002
Woodruff Fund Teaching Award, Emory University
2003
Harvard-Longwood Visiting Professor
2004
Member, Southern Surgical Association
2005
Fellow, American Institute of Medical and Biological Engineering
2006
Member, American Surgical Association
2008
John Mannick Visiting Professor, Brigham and Women's Hospital
2008 - 2010
President, International Society of Applied Cardiovascular Biology
2010
Milton F. Bryant Lecture, University of Michigan
2011
Inaugural Brandi Rutherford Lecture, Johns Hopkins School of Medicine
2011
Emile Holman Lecture, Stanford University
2012
Charles B. Huggins Lecture, University of Chicago
2012
Robert B. Smith, III Lecture, Emory University
2013
Robert O. Gregg Lecture, SUNY-Upstate
2013
Paul D. Abramson Lecture, Louisiana State University
2013
Clemson Award for Applied Research, Society for Biomaterials
2014
Wiliam H. Baker Lecture, Loyola University
2014
Institute of Medicine, National Academy of Medicine
2014
Ori Rotstein Lecture, University of Toronto
2014
Visiting Professor, Chinese PLA Medical School, Beijing, China
2016
John Mannick Visiting Professor in Surgery, Brigham and Women’s Hospital
2016
Edelstone-Bendix Visiting Professor, Northwestern University
2017
Fraser Gurd Visiting Professor, McGill University

Overview
Dr. Chaikof was born and raised in Toronto and earned BA and MD degrees at the Johns Hopkins University in Baltimore. He completed a residency in general surgery at the Massachusetts General Hospital and while a surgical resident, received a PhD in Chemical Engineering at the Massachusetts Institute of Technology with a focus on artificial organs and the design of biomaterials for reconstructive surgery. Following his surgical training in Boston, he completed additional training in Vascular Surgery at the Emory University School of Medicine where he joined the surgical faculty, most recently holding the John E. Skandalakis Chair of Surgery at Emory University, serving as Chief of Vascular Surgery and Director of the Residency in Vascular Surgery. While at Emory University, Dr. Chaikof held secondary appointments as an Adjunct Professor in the School of Chemical and Biomolecular Engineering at the Georgia Institute of Technology and was a member of the faculty in the Department of Biomedical Engineering.

In 2010, Dr. Chaikof was appointed as the Johnson and Johnson Professor of Surgery at Harvard Medical School and Chairman of the Department of Surgery and Surgeon-in-Chief of the Beth Israel Deaconess Medical Center. A surgeon and biomedical engineer, he is a member of the Wyss Institute of Biological Inspired Engineering and the Harvard Stem Cell Institute. He is internationally recognized for his many original and innovative contributions to vascular surgery through his basic science, clinical, and translational studies. He has changed the way in which patient with aortic aneurysms are evaluated and treated. His work in biomedical engineering and materials science has lead to the development of an advance generation of cardiovascular materials, devices, cell based therapies and pharmacotherapeutics based upon the principles of biomimetics, molecular and tissue engineering, as well as micro- and nanofabrication technologies. In 2013, he was the recipient of the Clemson Award for Applied Research from the Society for Biomaterials. Dr. Chaikof is the Editor of the Atlas of Vascular Surgery and Endovascular Therapy: Anatomy and Technique, published by Elsevier in English, Portuguese, and Mandarin editions. In 2014, Dr. Chaikof was elected to the Institute of Medicine of the National Academies.

Lab web site: http://chaikoflab.org/

Mentoring
Available: 09/01/11, Expires: 08/31/19

The control of blood clot formation on molecularly engineered surfaces remains a hurdle in the development of a small diameter arterial prosthesis critical to the fields of cardiac, plastic, and vascular surgery, as well as to the development of a permanently implantable artificial kidney, liver, or lung. We postulate that a clinically durable blood contacting surface can achieved by incorporating onto or within the material actively anti-thrombogenic mechanisms that are operative under a range of hemodynamic conditions. Ongoing research in our lab is directed at (i) engineering molecularly defined surfaces that prevent blood clotting in vitro and in vivo; and (ii) development of computational FEM models using MatchCad and Comsol programs that describe surface induced coagulation events under flow as a design tool for this effort.

Available: 09/01/11, Expires: 08/31/19

At the beginning of the twenty-first century, we are witnessing a remarkable convergence of our synthetic and physical technologies with the world of molecular biology, which will provide unprecedented opportunities for the creation of novel, functional biomolecules using biosynthetic and chemical strategies. Our group is involved in the design of living artificial organs. Most applications are directed at the fabrication of cardiovascular organs (e.g. tissue engineered blood vessels).

Engineering collagen-based arterial substitutes that recapitulate native vessel structural and functional properties
Soma Weiss, 04/01/22 - 12/28/18

Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. U01HL143365 (ZWICKER, JEFFREY) Aug 1, 2018 - Jul 31, 2023
    NIH/NHLBI
    Biomarkers and mechanisms in cancer associated thrombosis
    Role: Co-Principal Investigator
  2. K12HL141953 (SACKSTEIN, ROBERT) Jul 1, 2018 - Jun 30, 2023
    NIH/NHLBI
    Forging Translational Glycobiologists: Intermeshing Glycoscience Training and Clinical Education
    Role: Co-Principal Investigator
  3. R01DK107405 (CHAIKOF, ELLIOT) Mar 1, 2016 - Feb 29, 2020
    NIH/NIDDK
    A PSGL-1 Glycopeptide Mimetic for Treatment of Metabolic Syndrome
    Role: Principal Investigator
  4. U01GM116196 (CHAIKOF, ELLIOT) Sep 1, 2015 - May 31, 2019
    NIH/NIGMS
    Facile Synthesis of Glycosulfopeptides and Related Bioconjugates
    Role: Principal Investigator
  5. R01HL128237 (CHAIKOF, ELLIOT) Aug 1, 2015 - May 31, 2019
    NIH/NHLBI
    A PSGL-1 Glycopeptide Mimetic for Treatment of Venous Thromboembolism
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Lagoo J, Berry WR, Miller K, Neal BJ, Sato L, Lillemoe KD, Doherty GM, Kasser JR, Chaikof EL, Gawande AA, Haynes AB. Multisource Evaluation of Surgeon Behavior Is Associated With Malpractice Claims. Ann Surg. 2019 Jul; 270(1):84-90. PMID: 29578910.
    Citations:    Fields:    
  2. Maitz MF, Martins MCL, Grabow N, Matschegewski C, Huang N, Chaikof EL, Barbosa MA, Werner C, Sperling C. The blood compatibility challenge. Part 4: Surface modification for hemocompatible materials: Passive and active approaches to guide blood-material interactions. Acta Biomater. 2019 Jun 19. PMID: 31226481.
    Citations:    
  3. Tsikis S, Fleishman A, Chaikof EL, Rodrigue JR. Design and Implementation of an Infrastructure Program to Support Clinical Research in Surgery. J Surg Res. 2019 Sep; 241:264-270. PMID: 31035141.
    Citations:    
  4. Chaikof EL. Reply. J Vasc Surg. 2019 Mar; 69(3):975-976. PMID: 30798849.
    Citations:    
  5. McCallum JC, Wyers MC, Soden PA, Eidt JF, Guzman RJ, Schermerhorn ML, Chaikof EL, Hamdan AD. Vascular fellow and resident experience performing infrapopliteal revascularization with endovascular procedures and vein bypass during training. J Vasc Surg. 2018 11; 68(5):1533-1537. PMID: 30360842.
    Citations:    Fields:    
  6. Cauley R, Wu WW, Doval A, Chaikof E, Ho KKL, Iorio ML. Identifying Complications and Optimizing Consultations following Transradial Arterial Access for Cardiac Procedures. Ann Vasc Surg. 2019 Apr; 56:87-96. PMID: 30342206.
    Citations:    Fields:    
  7. Hanjaya-Putra D, Haller C, Wang X, Dai E, Lim B, Liu L, Jaminet P, Yao J, Searle A, Bonnard T, Hagemeyer CE, Peter K, Chaikof EL. Platelet-targeted dual pathway antithrombotic inhibits thrombosis with preserved hemostasis. JCI Insight. 2018 Aug 09; 3(15). PMID: 30089712.
    Citations:    Fields:    
  8. Sardar MYR, Mandhapati AR, Park S, Wever WJ, Cummings RD, Chaikof EL. Convergent Synthesis of Sialyl LewisX- O-Core-1 Threonine. J Org Chem. 2018 05 04; 83(9):4963-4972. PMID: 29638128.
    Citations:    Fields:    
  9. Kudelka MR, Nairn AV, Sardar MY, Sun X, Chaikof EL, Ju T, Moremen KW, Cummings RD. Isotopic labeling with cellular O-glycome reporter/amplification (ICORA) for comparative O-glycomics of cultured cells. Glycobiology. 2018 04 01; 28(4):214-222. PMID: 29390058.
    Citations:    Fields:    Translation:HumansCells
  10. Patel MS, Tomich D, Kent TS, Chaikof EL, Rodrigue JR. A Program for Promoting Clinical Scholarship in General Surgery. J Surg Educ. 2018 Jul - Aug; 75(4):854-860. PMID: 29398630.
    Citations:    Fields:    
  11. Chaikof EL, Dalman RL, Eskandari MK, Jackson BM, Lee WA, Mansour MA, Mastracci TM, Mell M, Murad MH, Nguyen LL, Oderich GS, Patel MS, Schermerhorn ML, Starnes BW. The Society for Vascular Surgery practice guidelines on the care of patients with an abdominal aortic aneurysm. J Vasc Surg. 2018 01; 67(1):2-77.e2. PMID: 29268916.
    Citations: 7     Fields:    Translation:Humans
  12. Ayala P, Dai E, Hawes M, Liu L, Chaudhuri O, Haller CA, Mooney DJ, Chaikof EL. Evaluation of a bioengineered construct for tissue engineering applications. J Biomed Mater Res B Appl Biomater. 2018 Aug; 106(6):2345-2354. PMID: 29130596.
    Citations: 1     Fields:    
  13. Sardar MYR, Krishnamurthy VR, Park S, Mandhapati AR, Wever WJ, Park D, Cummings RD, Chaikof EL. Synthesis of LewisX-O-Core-1 threonine: A building block for O-linked LewisX glycopeptides. Carbohydr Res. 2017 Nov 27; 452:47-53. PMID: 29065342.
    Citations:    Fields:    Translation:Cells
  14. Morikis VA, Chase S, Wun T, Chaikof EL, Magnani JL, Simon SI. Selectin catch-bonds mechanotransduce integrin activation and neutrophil arrest on inflamed endothelium under shear flow. Blood. 2017 11 09; 130(19):2101-2110. PMID: 28811304.
    Citations: 4     Fields:    Translation:HumansCellsCTClinical Trials
  15. Zaiem F, Almasri J, Tello M, Prokop LJ, Chaikof EL, Murad MH. A systematic review of surveillance after endovascular aortic repair. J Vasc Surg. 2018 01; 67(1):320-331.e37. PMID: 28662928.
    Citations:    Fields:    Translation:Humans
  16. Patel MS, Chaikof EL. Ruptured aneurysm systems of care: A national imperative to improve clinical outcomes. J Vasc Surg. 2017 03; 65(3):589-590. PMID: 28236911.
    Citations:    Fields:    Translation:Humans
  17. Patel MS, Miranda-Nieves D, Chen J, Haller CA, Chaikof EL. Targeting P-selectin glycoprotein ligand-1/P-selectin interactions as a novel therapy for metabolic syndrome. Transl Res. 2017 05; 183:1-13. PMID: 28034759.
    Citations: 1     Fields:    Translation:Humans
  18. Patel MS, Chaikof EL. Disclosing Industry Relationships-A Patient-Centered Approach. JAMA Surg. 2016 10 01; 151(10):895-896. PMID: 27366991.
    Citations:    Fields:    Translation:Humans
  19. Chen J, Haller CA, Chaikof EL. Immune checkpoint regulator: a new assignment proposed for the classic adhesion molecule P-selectin glycoprotein ligand-1. Transl Cancer Res. 2016 Oct; 5(Suppl 4):S668-S671. PMID: 30613475.
    Citations:    
  20. Chen J, Howell C, Haller CA, Patel MS, Ayala P, Moravec KA, Dai E, Liu L, Sotiri I, Aizenberg M, Aizenberg J, Chaikof EL. An immobilized liquid interface prevents device associated bacterial infection in vivo. Biomaterials. 2017 01; 113:80-92. PMID: 27810644.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  21. Patel MS, Chaikof EL. Promoting Creativity and Innovation in a Structured Learning Environment. Ann Surg. 2016 Jul; 264(1):39-40. PMID: 26835984.
    Citations:    Fields:    Translation:Humans
  22. Angsana J, Chen J, Liu L, Haller CA, Chaikof EL. Efferocytosis as a regulator of macrophage chemokine receptor expression and polarization. Eur J Immunol. 2016 07; 46(7):1592-9. PMID: 27139187.
    Citations: 4     Fields:    Translation:AnimalsCells
  23. Ham HO, Qu Z, Haller CA, Dorr BM, Dai E, Kim W, Liu DR, Chaikof EL. In situ regeneration of bioactive coatings enabled by an evolved Staphylococcus aureus sortase A. Nat Commun. 2016 Apr 13; 7:11140. PMID: 27073027.
    Citations: 2     Fields:    Translation:AnimalsCells
  24. Gruzdys V, Tang J, Chaikof E, Sun XL. Synthesis of Chain-End Functionalized Glycopolymers via Cyanoxyl-Mediated Free Radical Polymerization (CMFRP). Methods Mol Biol. 2016; 1367:3-12. PMID: 26537460.
    Citations:    Fields:    Translation:Cells
  25. Dydek EV, Chaikof EL. Simulated thrombin responses in venous valves. J Vasc Surg Venous Lymphat Disord. 2016 07; 4(3):329-35. PMID: 27318053.
    Citations: 1     Fields:    Translation:Humans
  26. Ayala P, Caves J, Dai E, Siraj L, Liu L, Chaudhuri O, Haller CA, Mooney DJ, Chaikof EL. Engineered composite fascia for stem cell therapy in tissue repair applications. Acta Biomater. 2015 Oct; 26:1-12. PMID: 26283165.
    Citations: 1     Fields:    Translation:HumansAnimals
  27. Naik N, Hanjaya-Putra D, Haller CA, Allen MG, Chaikof EL. Rapid homogeneous endothelialization of high aspect ratio microvascular networks. Biomed Microdevices. 2015 Aug; 17(4):83. PMID: 26227213.
    Citations:    Fields:    Translation:HumansCells
  28. Patsch C, Challet-Meylan L, Thoma EC, Urich E, Heckel T, O'Sullivan JF, Grainger SJ, Kapp FG, Sun L, Christensen K, Xia Y, Florido MH, He W, Pan W, Prummer M, Warren CR, Jakob-Roetne R, Certa U, Jagasia R, Freskgård PO, Adatto I, Kling D, Huang P, Zon LI, Chaikof EL, Gerszten RE, Graf M, Iacone R, Cowan CA. Generation of vascular endothelial and smooth muscle cells from human pluripotent stem cells. Nat Cell Biol. 2015 Aug; 17(8):994-1003. PMID: 26214132.
    Citations: 51     Fields:    Translation:HumansAnimalsCells
  29. Nurudeen SM, Kwakye G, Berry WR, Chaikof EL, Lillemoe KD, Millham F, Rubin M, Schwaitzberg S, Shamberger RC, Zinner MJ, Sato L, Lipsitz S, Gawande AA, Haynes AB. Can 360-Degree Reviews Help Surgeons? Evaluation of Multisource Feedback for Surgeons in a Multi-Institutional Quality Improvement Project. J Am Coll Surg. 2015 Oct; 221(4):837-44. PMID: 26272014.
    Citations: 3     Fields:    Translation:Humans
  30. Dydek EV, Chaikof EL. Simulated Thrombin Generation in the Presence of Surface-Bound Heparin and Circulating Tissue Factor. Ann Biomed Eng. 2016 Apr; 44(4):1072-84. PMID: 26168717.
    Citations: 2     Fields:    
  31. Krishnamurthy VR, Sardar MY, Ying Y, Song X, Haller C, Dai E, Wang X, Hanjaya-Putra D, Sun L, Morikis V, Simon SI, Woods RJ, Cummings RD, Chaikof EL. Glycopeptide analogues of PSGL-1 inhibit P-selectin in vitro and in vivo. Nat Commun. 2015 Mar 31; 6:6387. PMID: 25824568.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  32. Angsana J, Chen J, Smith S, Xiao J, Wen J, Liu L, Haller CA, Chaikof EL. Syndecan-1 modulates the motility and resolution responses of macrophages. Arterioscler Thromb Vasc Biol. 2015 Feb; 35(2):332-40. PMID: 25550207.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  33. Kim W, Haller C, Dai E, Wang X, Hagemeyer CE, Liu DR, Peter K, Chaikof EL. Targeted antithrombotic protein micelles. Angew Chem Int Ed Engl. 2015 Jan 26; 54(5):1461-5. PMID: 25504546.
    Citations: 3     Fields:    Translation:HumansCells
  34. Dorr BM, Ham HO, An C, Chaikof EL, Liu DR. Reprogramming the specificity of sortase enzymes. Proc Natl Acad Sci U S A. 2014 Sep 16; 111(37):13343-8. PMID: 25187567.
    Citations: 18     Fields:    Translation:HumansCells
  35. Chaikof EL, Cambria RP (Eds). Atlas of Vascular Surgery and Endovascular Therapy: Anatomy and Technique. 2014; 856.
  36. Kumar VA, Martinez AW, Caves JM, Naik N, Haller CA, Chaikof EL. Microablation of collagen-based substrates for soft tissue engineering. Biomed Mater. 2014 Feb; 9(1):011002. PMID: 24457193.
    Citations: 3     Fields:    Translation:AnimalsCells
  37. Kumar VA, Caves JM, Haller CA, Dai E, Li L, Grainger S, Chaikof EL. Collagen-Based Substrates with Tunable Strength for Soft Tissue Engineering. Biomater Sci. 2013 Nov 01; 1(11). PMID: 24349707.
    Citations: 5     Fields:    
  38. Gagner JE, Kim W, Chaikof EL. Designing protein-based biomaterials for medical applications. Acta Biomater. 2014 Apr; 10(4):1542-57. PMID: 24121196.
    Citations: 10     Fields:    Translation:HumansAnimals
  39. Lo RC, Bensley RP, Dahlberg SE, Matyal R, Hamdan AD, Wyers M, Chaikof EL, Schermerhorn ML. Presentation, treatment, and outcome differences between men and women undergoing revascularization or amputation for lower extremity peripheral arterial disease. J Vasc Surg. 2014 Feb; 59(2):409-418.e3. PMID: 24080134.
    Citations: 16     Fields:    Translation:Humans
  40. Gilmore D, Dib M, Evenson A, Schermerhorn M, Wyers M, Chaikof E, Hamdan A. Endovascular management of critical limb ischemia in renal transplant patients. Ann Vasc Surg. 2014 Jan; 28(1):159-63. PMID: 24011817.
    Citations: 1     Fields:    Translation:Humans
  41. Martinez AW, Caves JM, Ravi S, Li W, Chaikof EL. Effects of crosslinking on the mechanical properties, drug release and cytocompatibility of protein polymers. Acta Biomater. 2014 Jan; 10(1):26-33. PMID: 23993944.
    Citations: 7     Fields:    Translation:HumansCells
  42. Naik N, Caves J, Chaikof EL, Allen MG. Generation of spatially aligned collagen fiber networks through microtransfer molding. Adv Healthc Mater. 2014 Mar; 3(3):367-74. PMID: 24039146.
    Citations: 3     Fields:    Translation:AnimalsCells
  43. Glaser JD, Bensley RP, Hurks R, Dahlberg S, Hamdan AD, Wyers MC, Chaikof EL, Schermerhorn ML. Fate of the contralateral limb after lower extremity amputation. J Vasc Surg. 2013 Dec; 58(6):1571-1577.e1. PMID: 23921246.
    Citations: 3     Fields:    Translation:Humans
  44. Liang P, Hurks R, Bensley RP, Hamdan A, Wyers M, Chaikof E, Schermerhorn ML. The rise and fall of renal artery angioplasty and stenting in the United States, 1988-2009. J Vasc Surg. 2013 Nov; 58(5):1331-8.e1. PMID: 23810297.
    Citations: 5     Fields:    Translation:Humans
  45. Qu Z, Krishnamurthy V, Haller CA, Dorr BM, Marzec UM, Hurst S, Hinds MT, Hanson SR, Liu DR, Chaikof EL. Immobilization of actively thromboresistant assemblies on sterile blood-contacting surfaces. Adv Healthc Mater. 2014 Jan; 3(1):30-5. PMID: 23788402.
    Citations: 5     Fields:    Translation:AnimalsCells
  46. Kumar VA, Caves JM, Haller CA, Dai E, Liu L, Grainger S, Chaikof EL. Acellular vascular grafts generated from collagen and elastin analogs. Acta Biomater. 2013 Sep; 9(9):8067-74. PMID: 23743129.
    Citations: 17     Fields:    Translation:AnimalsCells
  47. Bensley RP, Curran T, Hurks R, Lo RC, Wyers MC, Hamdan AD, Chaikof EL, Schermerhorn ML. Open repair of intact thoracoabdominal aortic aneurysms in the American College of Surgeons National Surgical Quality Improvement Program. J Vasc Surg. 2013 Oct; 58(4):894-900. PMID: 23642916.
    Citations: 2     Fields:    Translation:HumansPHPublic Health
  48. Yoshida S, Bensley RP, Glaser JD, Nabzdyk CS, Hamdan AD, Wyers MC, Chaikof EL, Schermerhorn ML. The current national criteria for carotid artery stenting overestimate its efficacy in patients who are symptomatic and at high risk. J Vasc Surg. 2013 Jul; 58(1):120-7. PMID: 23566490.
    Citations: 2     Fields:    Translation:Humans
  49. Bensley RP, Yoshida S, Lo RC, Fokkema M, Hamdan AD, Wyers MC, Chaikof EL, Schermerhorn ML. Accuracy of administrative data versus clinical data to evaluate carotid endarterectomy and carotid stenting. J Vasc Surg. 2013 Aug; 58(2):412-9. PMID: 23490294.
    Citations: 10     Fields:    Translation:Humans
  50. Hohmann JD, Wang X, Krajewski S, Selan C, Haller CA, Straub A, Chaikof EL, Nandurkar HH, Hagemeyer CE, Peter K. Delayed targeting of CD39 to activated platelet GPIIb/IIIa via a single-chain antibody: breaking the link between antithrombotic potency and bleeding? Blood. 2013 Apr 18; 121(16):3067-75. PMID: 23380744.
    Citations: 12     Fields:    Translation:HumansAnimalsCells
  51. Siracuse JJ, Nandivada P, Giles KA, Hamdan AD, Wyers MC, Chaikof EL, Pomposelli FB, Schermerhorn ML. Prosthetic graft infections involving the femoral artery. J Vasc Surg. 2013 Mar; 57(3):700-5. PMID: 23312940.
    Citations: 6     Fields:    Translation:HumansCells
  52. Lee AM, Chaikof EL. Is the abdominal aortic aneurysm rupture rate decreasing? Adv Surg. 2013; 47:271-86. PMID: 24298856.
    Citations: 1     Fields:    Translation:Humans
  53. Lee AM, Chaikof EL. Is the abdominal aortic aneurysm rupture rate decreasing? Adv Surg. 2013; 47(1):271-86. PMID: 25293465.
    Citations:    
  54. Ravi S, Caves JM, Martinez AW, Haller CA, Chaikof EL. Incorporation of fibronectin to enhance cytocompatibility in multilayer elastin-like protein scaffolds for tissue engineering. J Biomed Mater Res A. 2013 Jul; 101(7):1915-25. PMID: 23225639.
    Citations: 8     Fields:    Translation:AnimalsCells
  55. Callery MP, Pratt WB, Kent TS, Chaikof EL, Vollmer CM. A prospectively validated clinical risk score accurately predicts pancreatic fistula after pancreatoduodenectomy. J Am Coll Surg. 2013 Jan; 216(1):1-14. PMID: 23122535.
    Citations: 105     Fields:    Translation:Humans
  56. Schermerhorn ML, Bensley RP, Giles KA, Hurks R, O'malley AJ, Cotterill P, Chaikof E, Landon BE. Changes in abdominal aortic aneurysm rupture and short-term mortality, 1995-2008: a retrospective observational study. Ann Surg. 2012 Oct; 256(4):651-8. PMID: 22964737.
    Citations: 33     Fields:    Translation:Humans
  57. Mets JM, Wilson JT, Cui W, Chaikof EL. An automated process for layer-by-layer assembly of polyelectrolyte multilayer thin films on viable cell aggregates. Adv Healthc Mater. 2013 Feb; 2(2):266-70. PMID: 23184761.
    Citations: 3     Fields:    Translation:Animals
  58. Ravi S, Caves JM, Martinez AW, Xiao J, Wen J, Haller CA, Davis ME, Chaikof EL. Effect of bone marrow-derived extracellular matrix on cardiac function after ischemic injury. Biomaterials. 2012 Nov; 33(31):7736-45. PMID: 22819498.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  59. Jordan SW, Corriere MA, Vossen CY, Rosendaal FR, Chaikof EL. Flow-simulated thrombin generation profiles as a predictor of thrombotic risk among pre-menopausal women. Thromb Haemost. 2012 Aug; 108(2):258-65. PMID: 22688389.
    Citations: 1     Fields:    Translation:Humans
  60. Nandivada P, Lagisetty KH, Giles K, Pomposelli FB, Chaikof EL, Schermerhorn ML, Wyers MC, Hamdan AD. The impact of endovascular procedures on fellowship training in lower extremity revascularization. J Vasc Surg. 2012 Jun; 55(6):1814-20. PMID: 22608046.
    Citations: 2     Fields:    Translation:Humans
  61. Chaikof EL. Invited commentary. J Vasc Surg. 2012 May; 55(5):1304-5. PMID: 22542342.
    Citations:    Fields:    Translation:HumansPHPublic Health
  62. Kim W, Brady C, Chaikof EL. Amphiphilic protein micelles for targeted in vivo imaging. Acta Biomater. 2012 Jul; 8(7):2476-82. PMID: 22504077.
    Citations: 4     Fields:    Translation:AnimalsCells
  63. Bensley RP, Hurks R, Huang Z, Pomposelli F, Hamdan A, Wyers M, Chaikof E, Schermerhorn ML. Ultrasound-guided percutaneous endovascular aneurysm repair success is predicted by access vessel diameter. J Vasc Surg. 2012 Jun; 55(6):1554-61. PMID: 22360918.
    Citations: 11     Fields:    Translation:Humans
  64. Siracuse JJ, Giles KA, Pomposelli FB, Hamdan AD, Wyers MC, Chaikof EL, Nedeau AE, Schermerhorn ML. Results for primary bypass versus primary angioplasty/stent for intermittent claudication due to superficial femoral artery occlusive disease. J Vasc Surg. 2012 Apr; 55(4):1001-7. PMID: 22301210.
    Citations: 16     Fields:    Translation:Humans
  65. Ravi S, Haller CA, Sallach RE, Chaikof EL. Cell behavior on a CCN1 functionalized elastin-mimetic protein polymer. Biomaterials. 2012 Mar; 33(8):2431-8. PMID: 22212194.
    Citations: 3     Fields:    Translation:HumansCells
  66. Xiao J, Angsana J, Wen J, Smith SV, Park PW, Ford ML, Haller CA, Chaikof EL. Syndecan-1 displays a protective role in aortic aneurysm formation by modulating T cell-mediated responses. Arterioscler Thromb Vasc Biol. 2012 Feb; 32(2):386-96. PMID: 22173227.
    Citations: 9     Fields:    Translation:AnimalsCells
  67. Krishna UM, Martinez AW, Caves JM, Chaikof EL. Hydrazone self-crosslinking of multiphase elastin-like block copolymer networks. Acta Biomater. 2012 Mar; 8(3):988-97. PMID: 22154858.
    Citations: 2     Fields:    Translation:HumansAnimals
  68. Kim W, Xiao J, Chaikof EL. Recombinant amphiphilic protein micelles for drug delivery. Langmuir. 2011 Dec 06; 27(23):14329-34. PMID: 21973265.
    Citations: 7     Fields:    Translation:Animals
  69. Ravi S, Krishnamurthy VR, Caves JM, Haller CA, Chaikof EL. Maleimide-thiol coupling of a bioactive peptide to an elastin-like protein polymer. Acta Biomater. 2012 Feb; 8(2):627-35. PMID: 22061108.
    Citations: 11     Fields:    Translation:HumansAnimalsCells
  70. Qu Z, Muthukrishnan S, Urlam MK, Haller CA, Jordan SW, Kumar VA, Marzec UM, Elkasabi Y, Lahann J, Hanson SR, Chaikof EL. A biologically active surface enzyme assembly that attenuates thrombus formation. Adv Funct Mater. 2011 Dec 20; 21(24):4736-4743. PMID: 23532366.
    Citations: 5