Harvard Catalyst Profiles

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Andre Kleber, M.D.


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Kléber AG, Rosen MR, Janse MJ, Noble D. Edward E. Carmeliet, MD, PhD (January 4, 1930-April 5, 2021): A pioneer in cardiac cellular electrophysiology. Heart Rhythm. 2021 Aug; 18(8):1460-1461. PMID: 34334159.
    Citations:    Fields:    
  2. Kleber AG, Wit AL. The Interaction Between Na+ and Ca2+ Inward Currents in Cardiac Propagation. Circ Res. 2020 12 04; 127(12):1549-1551. PMID: 33270548.
    Citations:    Fields:    
  3. Yadid M, Lind JU, Ardoña HAM, Sheehy SP, Dickinson LE, Eweje F, Bastings MMC, Pope B, O'Connor BB, Straubhaar JR, Budnik B, Kleber AG, Parker KK. Endothelial extracellular vesicles contain protective proteins and rescue ischemia-reperfusion injury in a human heart-on-chip. Sci Transl Med. 2020 10 14; 12(565). PMID: 33055246.
    Citations: 6     Fields:    Translation:HumansCells
  4. Xiao S, Shimura D, Baum R, Hernandez DM, Agvanian S, Nagaoka Y, Katsumata M, Lampe PD, Kleber AG, Hong T, Shaw RM. Auxiliary trafficking subunit GJA1-20k protects connexin-43 from degradation and limits ventricular arrhythmias. J Clin Invest. 2020 09 01; 130(9):4858-4870. PMID: 32525845.
    Citations: 7     Fields:    Translation:AnimalsCells
  5. Anter E, Neuzil P, Reddy VY, Petru J, Park KM, Sroubek J, Leshem E, Zimetbaum PJ, Buxton AE, Kleber AG, Shen C, Wit AL. Ablation of Reentry-Vulnerable Zones Determined by Left Ventricular Activation From Multiple Directions: A Novel Approach for Ventricular Tachycardia Ablation: A Multicenter Study (PHYSIO-VT). Circ Arrhythm Electrophysiol. 2020 06; 13(6):e008625. PMID: 32372657.
    Citations: 3     Fields:    Translation:Humans
  6. Ghazizadeh Z, Kiviniemi T, Olafsson S, Plotnick D, Beerens ME, Zhang K, Gillon L, Steinbaugh MJ, Barrera V, Sui SH, Werdich AA, Kapur S, Eranti A, Gunn J, Jalkanen J, Airaksinen J, Kleber AG, Hollmén M, MacRae CA. Metastable Atrial State Underlies the Primary Genetic Substrate for MYL4 Mutation-Associated Atrial Fibrillation. Circulation. 2020 01 28; 141(4):301-312. PMID: 31735076.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  7. Rottmann M, Kleber AG, Barkagan M, Sroubek J, Leshem E, Shapira-Daniels A, Buxton AE, Anter E. Activation During Sinus Rhythm in Ventricles With Healed Infarction: Differentiation Between Arrhythmogenic and Nonarrhythmogenic Scar. Circ Arrhythm Electrophysiol. 2019 10; 12(10):e007879. PMID: 31597477.
    Citations: 1     Fields:    Translation:Animals
  8. Park SJ, Zhang D, Qi Y, Li Y, Lee KY, Bezzerides VJ, Yang P, Xia S, Kim SL, Liu X, Lu F, Pasqualini FS, Campbell PH, Geva J, Roberts AE, Kleber AG, Abrams DJ, Pu WT, Parker KK. Insights Into the Pathogenesis of Catecholaminergic Polymorphic Ventricular Tachycardia From Engineered Human Heart Tissue. Circulation. 2019 07 30; 140(5):390-404. PMID: 31311300.
    Citations: 25     Fields:    Translation:HumansCells
  9. Anter E, Kleber AG, Rottmann M, Leshem E, Barkagan M, Tschabrunn CM, Contreras-Valdes FM, Buxton AE. Infarct-Related Ventricular Tachycardia: Redefining the Electrophysiological Substrate of the Isthmus During Sinus Rhythm. JACC Clin Electrophysiol. 2018 08; 4(8):1033-1048. PMID: 30139485.
    Citations: 17     Fields:    Translation:Animals
  10. Basheer WA, Xiao S, Epifantseva I, Fu Y, Kleber AG, Hong T, Shaw RM. GJA1-20k Arranges Actin to Guide Cx43 Delivery to Cardiac Intercalated Discs. Circ Res. 2017 Oct 13; 121(9):1069-1080. PMID: 28923791.
    Citations: 29     Fields:    Translation:HumansAnimalsCells
  11. Kucera JP, Rohr S, Kleber AG. Microstructure, Cell-to-Cell Coupling, and Ion Currents as Determinants of Electrical Propagation and Arrhythmogenesis. Circ Arrhythm Electrophysiol. 2017 09; 10(9). PMID: 28912204.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  12. Chelko SP, Asimaki A, Andersen P, Bedja D, Amat-Alarcon N, DeMazumder D, Jasti R, MacRae CA, Leber R, Kleber AG, Saffitz JE, Judge DP. Central role for GSK3ß in the pathogenesis of arrhythmogenic cardiomyopathy. JCI Insight. 2016 Apr 21; 1(5). PMID: 27170944.
    Citations: 44     Fields:    
  13. Melman YF, Shah R, Danielson K, Xiao J, Simonson B, Barth A, Chakir K, Lewis GD, Lavender Z, Truong QA, Kleber A, Das R, Rosenzweig A, Wang Y, Kass D, Singh JP, Das S. Response to Letter Regarding Article, "Circulating MicroRNA-30d Is Associated With Response to Cardiac Resynchronization Therapy in Heart Failure and Regulates Cardiomyocyte Apoptosis: A Translational Pilot Study". Circulation. 2016 Feb 09; 133(6):e389-e390. PMID: 26858296.
    Citations:    Fields:    Translation:HumansAnimalsCells
  14. Asimaki A, Protonotarios A, James CA, Chelko SP, Tichnell C, Murray B, Tsatsopoulou A, Anastasakis A, te Riele A, Kléber AG, Judge DP, Calkins H, Saffitz JE. Characterizing the Molecular Pathology of Arrhythmogenic Cardiomyopathy in Patient Buccal Mucosa Cells. Circ Arrhythm Electrophysiol. 2016 Feb; 9(2):e003688. PMID: 26850880.
    Citations: 12     Fields:    Translation:HumansCells
  15. Melman YF, Shah R, Danielson K, Xiao J, Simonson B, Barth A, Chakir K, Lewis GD, Lavender Z, Truong QA, Kleber A, Das R, Rosenzweig A, Wang Y, Kass D, Singh JP, Das S. Circulating MicroRNA-30d Is Associated With Response to Cardiac Resynchronization Therapy in Heart Failure and Regulates Cardiomyocyte Apoptosis: A Translational Pilot Study. Circulation. 2015 Jun 23; 131(25):2202-2216. PMID: 25995320.
    Citations: 61     Fields:    Translation:HumansAnimalsCells
  16. Asimaki A, Kleber AG, Saffitz JE. Pathogenesis of Arrhythmogenic Cardiomyopathy. Can J Cardiol. 2015 Nov; 31(11):1313-24. PMID: 26199027.
    Citations: 11     Fields:    Translation:Humans
  17. Kleber AG, Saffitz JE. Role of the intercalated disc in cardiac propagation and arrhythmogenesis. Front Physiol. 2014; 5:404. PMID: 25368581.
    Citations: 22     
  18. Asimaki A, Kapoor S, Plovie E, Karin Arndt A, Adams E, Liu Z, James CA, Judge DP, Calkins H, Churko J, Wu JC, MacRae CA, Kléber AG, Saffitz JE. Identification of a new modulator of the intercalated disc in a zebrafish model of arrhythmogenic cardiomyopathy. Sci Transl Med. 2014 Jun 11; 6(240):240ra74. PMID: 24920660.
    Citations: 93     Fields:    Translation:AnimalsCells
  19. McCain ML, Desplantez T, Kléber AG. Engineering cardiac cell junctions in vitro to study the intercalated disc. Cell Commun Adhes. 2014 Jun; 21(3):181-91. PMID: 24754499.
    Citations: 1     Fields:    Translation:HumansCells
  20. Wolf A, Baumbach JI, Kleber A, Maurer F, Maddula S, Favrod P, Jang M, Fink T, Volk T, Kreuer S. Multi-capillary column-ion mobility spectrometer (MCC-IMS) breath analysis in ventilated rats: a model with the feasibility of long-term measurements. J Breath Res. 2014 Mar; 8(1):016006. PMID: 24566204.
    Citations: 3     Fields:    Translation:HumansAnimals
  21. Zhang SS, Hong S, Kléber AG, Lee LP, Shaw RM. A micropatterning approach for imaging dynamic Cx43 trafficking to cell-cell borders. FEBS Lett. 2014 Apr 17; 588(8):1439-45. PMID: 24444605.
    Citations: 11     Fields:    Translation:HumansAnimalsCells
  22. Opthof T, Janse MJ, Kléber AG, Wellens HJ, Wilde AA, Coronel R. The works of Dirk Durrer (1918-1984). Neth Heart J. 2012 Oct; 20(10):430-3. PMID: 22875727.
    Citations: 5     
  23. Saffitz JE, Kléber AG. Gap junctions, slow conduction, and ventricular tachycardia after myocardial infarction. J Am Coll Cardiol. 2012 Sep 18; 60(12):1111-3. PMID: 22883635.
    Citations: 9     Fields:    Translation:Animals
  24. McCain ML, Lee H, Aratyn-Schaus Y, Kléber AG, Parker KK. Cooperative coupling of cell-matrix and cell-cell adhesions in cardiac muscle. Proc Natl Acad Sci U S A. 2012 Jun 19; 109(25):9881-6. PMID: 22675119.
    Citations: 57     Fields:    Translation:AnimalsCells
  25. Beauchamp P, Desplantez T, McCain ML, Li W, Asimaki A, Rigoli G, Parker KK, Saffitz JE, Kleber AG. Electrical coupling and propagation in engineered ventricular myocardium with heterogeneous expression of connexin43. Circ Res. 2012 May 25; 110(11):1445-53. PMID: 22518032.
    Citations: 18     Fields:    Translation:AnimalsCells
  26. Kondratyev AA, Didon JP, Hinnen-Oberer H, Lemay M, Kucera JP, Kleber AG. Virtual sources and sinks during extracellular field shocks in cardiac cell cultures: effects of source-sink interactions between adjacent tissue boundaries. Circ Arrhythm Electrophysiol. 2012 Apr; 5(2):391-9. PMID: 22387879.
    Citations:    Fields:    Translation:AnimalsCells
  27. Desplantez T, McCain ML, Beauchamp P, Rigoli G, Rothen-Rutishauser B, Parker KK, Kleber AG. Connexin43 ablation in foetal atrial myocytes decreases electrical coupling, partner connexins, and sodium current. Cardiovasc Res. 2012 Apr 01; 94(1):58-65. PMID: 22287588.
    Citations: 28     Fields:    Translation:AnimalsCells
  28. McCain ML, Desplantez T, Geisse NA, Rothen-Rutishauser B, Oberer H, Parker KK, Kleber AG. Cell-to-cell coupling in engineered pairs of rat ventricular cardiomyocytes: relation between Cx43 immunofluorescence and intercellular electrical conductance. Am J Physiol Heart Circ Physiol. 2012 Jan; 302(2):H443-50. PMID: 22081700.
    Citations: 24     Fields:    Translation:AnimalsCells
  29. Kléber AG. Gap junctions and conduction of cardiac excitation. Heart Rhythm. 2011 Dec; 8(12):1981-4. PMID: 21835153.
    Citations: 3     Fields:    Translation:HumansCells
  30. Kléber AG. The discovery of calcium ion channels in the heart was a landmark for the worldwide development of cardiovascular drugs. Eur Heart J. 2010 Jun; 31(11):1291-2. PMID: 20527708.
    Citations:    Fields:    
  31. Kléber AG. Na+ channel transfection to rescue propagation. Heart Rhythm. 2010 Aug; 7(8):1111-2. PMID: 20466071.
    Citations:    Fields:    Translation:AnimalsCells
  32. Kléber AG. Crosstalk between theoretical and experimental studies for the understanding of cardiac electrical impulse propagation. J Electrocardiol. 2007 Nov-Dec; 40(6 Suppl):S136-41. PMID: 17993310.
    Citations:    Fields:    Translation:HumansAnimals
  33. Muñoz V, Grzeda KR, Desplantez T, Pandit SV, Mironov S, Taffet SM, Rohr S, Kléber AG, Jalife J. Adenoviral expression of IKs contributes to wavebreak and fibrillatory conduction in neonatal rat ventricular cardiomyocyte monolayers. Circ Res. 2007 Aug 31; 101(5):475-83. PMID: 17626898.
    Citations: 33     Fields:    Translation:AnimalsCells
  34. Kléber AG. Cardiac cell-to-cell junctions as an origin of inherited arrhythmogenic disorders. Heart Rhythm. 2007 Sep; 4(9):1206-7. PMID: 17765622.
    Citations:    Fields:    Translation:HumansAnimalsCells
  35. Armbruster C, Tevaearai H, Kleber A, Carrel T, Giraud M. Strategies to induce cardiac differentiation of Mesenchymal Stem Cells. J Stem Cells Regen Med. 2007; 2(1):210-1. PMID: 24693006.
  36. Beauchamp P, Yamada KA, Baertschi AJ, Green K, Kanter EM, Saffitz JE, Kléber AG. Relative contributions of connexins 40 and 43 to atrial impulse propagation in synthetic strands of neonatal and fetal murine cardiomyocytes. Circ Res. 2006 Nov 24; 99(11):1216-24. PMID: 17053190.
    Citations: 41     Fields:    Translation:AnimalsCells
  37. Eschenhagen T, Zimmermann WH, Kléber AG. Electrical coupling of cardiac myocyte cell sheets to the heart. Circ Res. 2006 Mar 17; 98(5):573-5. PMID: 16543504.
    Citations: 10     Fields:    Translation:HumansAnimalsCells
  38. Kléber AG, Niggli E, McGuigan JA, Weingart R. The early years of cellular cardiac electrophysiology and Silvio Weidmann (1921-2005). Heart Rhythm. 2006 Mar; 3(3):353-9. PMID: 16500311.
    Citations: 1     Fields:    Translation:Humans
  39. Kléber AG. The shape of the electrical action-potential upstroke: a new aspect from optical measurements on the surface of the heart. Circ Res. 2005 Aug 05; 97(3):204-6. PMID: 16081874.
    Citations: 6     Fields:    Translation:Animals
  40. Beauchamp P, Choby C, Desplantez T, de Peyer K, Green K, Yamada KA, Weingart R, Saffitz JE, Kléber AG. Electrical propagation in synthetic ventricular myocyte strands from germline connexin43 knockout mice. Circ Res. 2004 Jul 23; 95(2):170-8. PMID: 15192022.
    Citations: 43     Fields:    Translation:AnimalsCells
  41. Kléber AG, Rudy Y. Basic mechanisms of cardiac impulse propagation and associated arrhythmias. Physiol Rev. 2004 Apr; 84(2):431-88. PMID: 15044680.
    Citations: 327     Fields:    Translation:HumansAnimalsCells
  42. Saffitz JE, Kléber AG. Effects of mechanical forces and mediators of hypertrophy on remodeling of gap junctions in the heart. Circ Res. 2004 Mar 19; 94(5):585-91. PMID: 15031271.
    Citations: 24     Fields:    Translation:AnimalsCells
  43. Kleber AG. From the needle to the optrode: assessment of cardiac intramural electrical activity. J Cardiovasc Electrophysiol. 2003 Nov; 14(11):1203-4. PMID: 14678135.
    Citations:    Fields:    Translation:Animals
  44. Kléber AG. Cell-to-cell coupling between host and donor cells in the in situ myocardium. Circ Res. 2003 Jun 13; 92(11):1176-8. PMID: 12805234.
    Citations:    Fields:    Translation:AnimalsCells
  45. Thomas SP, Kucera JP, Bircher-Lehmann L, Rudy Y, Saffitz JE, Kléber AG. Impulse propagation in synthetic strands of neonatal cardiac myocytes with genetically reduced levels of connexin43. Circ Res. 2003 Jun 13; 92(11):1209-16. PMID: 12730095.
    Citations: 51     Fields:    Translation:AnimalsCells
  46. Pimentel RC, Yamada KA, Kléber AG, Saffitz JE. Autocrine regulation of myocyte Cx43 expression by VEGF. Circ Res. 2002 Apr 05; 90(6):671-7. PMID: 11934834.
    Citations: 36     Fields:    Translation:AnimalsCells
  47. Baader AP, Büchler L, Bircher-Lehmann L, Kléber AG. Real time, confocal imaging of Ca(2+) waves in arterially perfused rat hearts. Cardiovasc Res. 2002 Jan; 53(1):105-15. PMID: 11744018.
    Citations: 7     Fields:    Translation:AnimalsCells
  48. Allessie MA, Boyden PA, Camm AJ, Kléber AG, Lab MJ, Legato MJ, Rosen MR, Schwartz PJ, Spooner PM, Van Wagoner DR, Waldo AL. Pathophysiology and prevention of atrial fibrillation. Circulation. 2001 Feb 06; 103(5):769-77. PMID: 11156892.
    Citations: 136     Fields:    Translation:HumansCells
  49. Kucera JP, Kléber AG, Rohr S. Slow conduction in cardiac tissue: insights from optical mapping at the cellular level. J Electrocardiol. 2001; 34 Suppl:57-64. PMID: 11781937.
    Citations: 5     Fields:    Translation:AnimalsCells
  50. Kleber AG. The fibrillating atrial myocardium. What can the detection of wave breaks tell us? Cardiovasc Res. 2000 Nov; 48(2):181-4. PMID: 11054463.
    Citations: 1     Fields:    Translation:HumansAnimals
  51. Beardslee MA, Lerner DL, Tadros PN, Laing JG, Beyer EC, Yamada KA, Kléber AG, Schuessler RB, Saffitz JE. Dephosphorylation and intracellular redistribution of ventricular connexin43 during electrical uncoupling induced by ischemia. Circ Res. 2000 Oct 13; 87(8):656-62. PMID: 11029400.
    Citations: 162     Fields:    Translation:AnimalsCells
  52. Tung L, Kléber AG. Virtual sources associated with linear and curved strands of cardiac cells. . 2000 Oct; 279(4):H1579-90. PMID: 11009444.
    Citations: 6     Translation:AnimalsCells
  53. Thomas SP, Bircher-Lehmann L, Thomas SA, Zhuang J, Saffitz JE, Kléber AG. Synthetic strands of neonatal mouse cardiac myocytes: structural and electrophysiological properties. Circ Res. 2000 Sep 15; 87(6):467-73. PMID: 10988238.
    Citations: 29     Fields:    Translation:AnimalsCells
  54. Zhuang J, Yamada KA, Saffitz JE, Kléber AG. Pulsatile stretch remodels cell-to-cell communication in cultured myocytes. Circ Res. 2000 Aug 18; 87(4):316-22. PMID: 10948066.
    Citations: 55     Fields:    Translation:AnimalsCells
  55. Gillis AM, Fast VG, Rohr S, Kléber AG. Mechanism of ventricular defibrillation. The role of tissue geometry in the changes in transmembrane potential in patterned myocyte cultures. Circulation. 2000 May 23; 101(20):2438-45. PMID: 10821823.
    Citations: 7     Fields:    Translation:AnimalsCells
  56. Kléber AG. ST-segment elevation in the electrocardiogram: a sign of myocardial ischemia. Cardiovasc Res. 2000 Jan 01; 45(1):111-8. PMID: 10728321.
    Citations: 16     Fields:    Translation:HumansAnimals
  57. Rohr S, Kléber AG, Kucera JP. Optical recording of impulse propagation in designer cultures. Cardiac tissue architectures inducing ultra-slow conduction. Trends Cardiovasc Med. 1999 Oct; 9(7):173-9. PMID: 10881747.
    Citations: 3     Fields:    Translation:AnimalsCells
  58. Kléber AG. Discontinuous propagation of the cardiac impulse and arrhythmogenesis. J Cardiovasc Electrophysiol. 1999 Jul; 10(7):1025-7. PMID: 10413383.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  59. Priori SG, Barhanin J, Hauer RN, Haverkamp W, Jongsma HJ, Kleber AG, McKenna WJ, Roden DM, Rudy Y, Schwartz K, Schwartz PJ, Towbin JA, Wilde AM. Genetic and molecular basis of cardiac arrhythmias: impact on clinical management part III. Circulation. 1999 Feb 09; 99(5):674-81. PMID: 9950666.
    Citations: 15     Fields:    Translation:Humans
  60. Priori SG, Barhanin J, Hauer RN, Haverkamp W, Jongsma HJ, Kleber AG, McKenna WJ, Roden DM, Rudy Y, Schwartz K, Schwartz PJ, Towbin JA, Wilde AM. Genetic and molecular basis of cardiac arrhythmias: impact on clinical management parts I and II. Circulation. 1999 Feb 02; 99(4):518-28. PMID: 9927398.
    Citations: 33     Fields:    Translation:Humans
  61. Priori SG, Barhanin J, Hauer RN, Haverkamp W, Jongsma HJ, Kleber AG, McKenna WJ, Roden DM, Rudy Y, Schwartz K, Schwartz PJ, Towbin JA, Wilde A. Genetic and molecular basis of cardiac arrhythmias; impact on clinical management. Study group on molecular basis of arrhythmias of the working group on arrhythmias of the european society of cardiology. Eur Heart J. 1999 Feb; 20(3):174-95. PMID: 10082151.
    Citations: 20     Fields:    Translation:HumansCells
  62. Kucera JP, Kléber AG, Rohr S. Slow conduction in cardiac tissue, II: effects of branching tissue geometry. Circ Res. 1998 Oct 19; 83(8):795-805. PMID: 9776726.
    Citations: 21     Fields:    Translation:AnimalsCells
  63. Rohr S, Kucera JP, Kléber AG. Slow conduction in cardiac tissue, I: effects of a reduction of excitability versus a reduction of electrical coupling on microconduction. Circ Res. 1998 Oct 19; 83(8):781-94. PMID: 9776725.
    Citations: 71     Fields:    Translation:AnimalsCells
  64. Janse MJ, Opthof T, Kléber AG. Animal models of cardiac arrhythmias. Cardiovasc Res. 1998 Jul; 39(1):165-77. PMID: 9764198.
    Citations: 18     Fields:    Translation:HumansAnimals
  65. Fast VG, Rohr S, Gillis AM, Kléber AG. Activation of cardiac tissue by extracellular electrical shocks: formation of 'secondary sources' at intercellular clefts in monolayers of cultured myocytes. Circ Res. 1998 Feb 23; 82(3):375-85. PMID: 9486666.
    Citations: 32     Fields:    Translation:AnimalsCells
  66. Rohr S, Kucera JP, Fast VG, Kléber AG. Paradoxical improvement of impulse conduction in cardiac tissue by partial cellular uncoupling. Science. 1997 Feb 07; 275(5301):841-4. PMID: 9012353.
    Citations: 85     Fields:    Translation:AnimalsCells
  67. Fast VG, Kléber AG. Role of wavefront curvature in propagation of cardiac impulse. Cardiovasc Res. 1997 Feb; 33(2):258-71. PMID: 9074688.
    Citations: 44     Fields:    Translation:Humans
  68. Kleber AG, Fast V. Molecular and cellular aspects of re-entrant arrhythmias. Basic Res Cardiol. 1997; 92 Suppl 1:111-9. PMID: 9202851.
    Citations: 2     Fields:    Translation:HumansAnimals
  69. Gillis AM, Fast VG, Rohr S, Kléber AG. Spatial changes in transmembrane potential during extracellular electrical shocks in cultured monolayers of neonatal rat ventricular myocytes. Circ Res. 1996 Oct; 79(4):676-90. PMID: 8831491.
    Citations: 13     Fields:    Translation:AnimalsCells
  70. Darrow BJ, Fast VG, Kléber AG, Beyer EC, Saffitz JE. Functional and structural assessment of intercellular communication. Increased conduction velocity and enhanced connexin expression in dibutyryl cAMP-treated cultured cardiac myocytes. Circ Res. 1996 Aug; 79(2):174-83. PMID: 8755993.
    Citations: 42     Fields:    Translation:AnimalsCells
  71. Fast VG, Darrow BJ, Saffitz JE, Kléber AG. Anisotropic activation spread in heart cell monolayers assessed by high-resolution optical mapping. Role of tissue discontinuities. Circ Res. 1996 Jul; 79(1):115-27. PMID: 8925559.
    Citations: 22     Fields:    Translation:AnimalsCells
  72. Kléber AG, Fast VG, Kucera J, Rohr S. [Physiology and pathophysiology of cardiac impulse conduction]. Z Kardiol. 1996; 85 Suppl 6:25-33. PMID: 9064973.
    Citations: 2     Fields:    Translation:HumansCells
  73. Yan GX, Chen J, Yamada KA, Kléber AG, Corr PB. Contribution of shrinkage of extracellular space to extracellular K+ accumulation in myocardial ischaemia of the rabbit. J Physiol. 1996 Jan 01; 490 ( Pt 1):215-28. PMID: 8745289.
    Citations: 8     Fields:    Translation:AnimalsCells
  74. Allessie A, Avkiran M, Borggrefe M, Carmeliet E, Cobbe SM, Dhein S, Haverkamp W, Hindricks G, Janse MJ, Kléber AG, et al. The role of basic arrhythmia research. The continued need for experiments in the intact heart and organism. Eur Heart J. 1995 Nov; 16(11):1469-75. PMID: 8881837.
    Citations: 1     Fields:    Translation:HumansAnimals
  75. Fast VG, Kléber AG. Block of impulse propagation at an abrupt tissue expansion: evaluation of the critical strand diameter in 2- and 3-dimensional computer models. Cardiovasc Res. 1995 Sep; 30(3):449-59. PMID: 7585837.
    Citations: 29     Fields:    Translation:Animals
  76. Fleischhauer J, Lehmann L, Kléber AG. Electrical resistances of interstitial and microvascular space as determinants of the extracellular electrical field and velocity of propagation in ventricular myocardium. Circulation. 1995 Aug 01; 92(3):587-94. PMID: 7634473.
    Citations: 21     Fields:    Translation:AnimalsCells
  77. Fast VG, Kléber AG. Cardiac tissue geometry as a determinant of unidirectional conduction block: assessment of microscopic excitation spread by optical mapping in patterned cell cultures and in a computer model. Cardiovasc Res. 1995 May; 29(5):697-707. PMID: 7606760.
    Citations: 40     Fields:    Translation:AnimalsCells
  78. Fast VG, Kléber AG. Anisotropic conduction in monolayers of neonatal rat heart cells cultured on collagen substrate. Circ Res. 1994 Sep; 75(3):591-5. PMID: 8062430.
    Citations: 22     Fields:    Translation:AnimalsCells
  79. Kleber AG. IK1 blockade as an antiarrhythmic mechanism. Cardiovasc Res. 1994 May; 28(5):720. PMID: 8068130.
    Citations: 1     Fields:    Translation:Humans
  80. Yamada KA, McHowat J, Yan GX, Donahue K, Peirick J, Kléber AG, Corr PB. Cellular uncoupling induced by accumulation of long-chain acylcarnitine during ischemia. Circ Res. 1994 Jan; 74(1):83-95. PMID: 8261598.
    Citations: 23     Fields:    Translation:Animals
  81. Fast VG, Kléber AG. Microscopic conduction in cultured strands of neonatal rat heart cells measured with voltage-sensitive dyes. Circ Res. 1993 Nov; 73(5):914-25. PMID: 8403261.
    Citations: 36     Fields:    Translation:AnimalsCells
  82. Clarke K, Stewart LC, Neubauer S, Balschi JA, Smith TW, Ingwall JS, Nédélec JF, Humphrey SM, Kléber AG, Springer CS. Extracellular volume and transsarcolemmal proton movement during ischemia and reperfusion: a 31P NMR spectroscopic study of the isovolumic rat heart. NMR Biomed. 1993 Jul-Aug; 6(4):278-86. PMID: 8217528.
    Citations: 7     Fields:    Translation:AnimalsCells
  83. Yan GX, Yamada KA, Kléber AG, McHowat J, Corr PB. Dissociation between cellular K+ loss, reduction in repolarization time, and tissue ATP levels during myocardial hypoxia and ischemia. Circ Res. 1993 Mar; 72(3):560-70. PMID: 8431984.
    Citations: 12     Fields:    Translation:AnimalsCells
  84. Kleber AG. [Elevation of the ST-segment in the electrocardiogram and ischemic injury current]. Schweiz Rundsch Med Prax. 1992 Sep 22; 81(39):1142-6. PMID: 1410997.
    Citations:    Fields:    
  85. Yan GX, Kléber AG. Changes in extracellular and intracellular pH in ischemic rabbit papillary muscle. Circ Res. 1992 Aug; 71(2):460-70. PMID: 1628400.
    Citations: 34     Fields:    Translation:AnimalsCells
  86. Kléber AG. [The mechanism of tachycardic arrhythmias]. Ther Umsch. 1992 Aug; 49(8):504-10. PMID: 1381526.
    Citations:    Fields:    Translation:HumansAnimals
  87. Cascio WE, Yan GX, Kléber AG. Early changes in extracellular potassium in ischemic rabbit myocardium. The role of extracellular carbon dioxide accumulation and diffusion. Circ Res. 1992 Feb; 70(2):409-22. PMID: 1735138.
    Citations: 14     Fields:    Translation:AnimalsCells
  88. Wilde AA, Kléber AG. Effect of norepinephrine and heart rate on intracellular sodium activity and membrane potential in beating guinea pig ventricular muscle. Circ Res. 1991 May; 68(5):1482-9. PMID: 2019003.
    Citations: 5     Fields:    Translation:Animals
  89. Rohr S, Schölly DM, Kléber AG. Patterned growth of neonatal rat heart cells in culture. Morphological and electrophysiological characterization. Circ Res. 1991 Jan; 68(1):114-30. PMID: 1984856.
    Citations: 65     Fields:    Translation:AnimalsCells
  90. Kléber AG. Mechanisms of ventricular arrhythmias: a perspective. J Cardiovasc Pharmacol. 1991; 17 Suppl 6:S1-8. PMID: 1723111.
    Citations: 2     Fields:    Translation:HumansAnimals
  91. Kléber AG. Consequences of acute ischemia for the electrical and mechanical function of the ventricular myocardium. A brief review. Experientia. 1990 Dec 01; 46(11-12):1162-7. PMID: 2253715.
    Citations: 6     Fields:    
  92. Cascio WE, Yan GX, Kléber AG. Passive electrical properties, mechanical activity, and extracellular potassium in arterially perfused and ischemic rabbit ventricular muscle. Effects of calcium entry blockade or hypocalcemia. Circ Res. 1990 Jun; 66(6):1461-73. PMID: 2344662.
    Citations: 16     Fields:    Translation:AnimalsCells
  93. Yan GX, Kleber AG, Cascio WE. [Electrical cell-to-cell coupling in the myocardium]. Sheng Li Ke Xue Jin Zhan. 1989 Oct; 20(4):294-300. PMID: 2561221.
    Citations:    Fields:    Translation:HumansAnimals
  94. Riegger CB, Alperovich G, Kléber AG. Effect of oxygen withdrawal on active and passive electrical properties of arterially perfused rabbit ventricular muscle. Circ Res. 1989 Mar; 64(3):532-41. PMID: 2917379.
    Citations: 7     Fields:    Translation:Animals
  95. Kléber AG. Conduction of the impulse in the ischemic myocardium--implications for malignant ventricular arrhythmias. Experientia. 1987 Oct 15; 43(10):1056-61. PMID: 3311794.
    Citations: 7     Fields:    Translation:Animals
  96. Kléber AG, Riegger CB, Janse MJ. Extracellular K+ and H+ shifts in early ischemia: mechanisms and relation to changes in impulse propagation. J Mol Cell Cardiol. 1987 Oct; 19 Suppl 5:35-44. PMID: 2448490.
    Citations: 11     Fields:    Translation:AnimalsCells
  97. Kléber AG, Riegger CB, Janse MJ. Electrical uncoupling and increase of extracellular resistance after induction of ischemia in isolated, arterially perfused rabbit papillary muscle. Circ Res. 1987 Aug; 61(2):271-9. PMID: 3621491.
    Citations: 67     Fields:    Translation:AnimalsCells
  98. Kléber AG, Riegger CB. Electrical constants of arterially perfused rabbit papillary muscle. J Physiol. 1987 Apr; 385:307-24. PMID: 3656162.
    Citations: 36     Fields:    Translation:AnimalsCells
  99. Kleber AG, Wilde AA. Regulation of intracellular sodium ions in acute reversible myocardial ischemia--a perspective. J Mol Cell Cardiol. 1986 Oct; 18 Suppl 4:27-30. PMID: 3023645.
    Citations: 1     Fields:    Translation:AnimalsCells
  100. Janse MJ, Kleber AG, Capucci A, Coronel R, Wilms-Schopman F. Electrophysiological basis for arrhythmias caused by acute ischemia. Role of the subendocardium. J Mol Cell Cardiol. 1986 Apr; 18(4):339-55. PMID: 3712446.
    Citations: 21     Fields:    Translation:Animals
  101. Wilde AA, Kléber AG. The combined effects of hypoxia, high K+, and acidosis on the intracellular sodium activity and resting potential in guinea pig papillary muscle. Circ Res. 1986 Feb; 58(2):249-56. PMID: 3948342.
    Citations: 14     Fields:    Translation:AnimalsCells
  102. Kléber AG, Janse MJ, Wilms-Schopmann FJ, Wilde AA, Coronel R. Changes in conduction velocity during acute ischemia in ventricular myocardium of the isolated porcine heart. Circulation. 1986 Jan; 73(1):189-98. PMID: 3940667.
    Citations: 43     Fields:    Translation:Animals
  103. Kléber AG. Extracellular potassium accumulation in acute myocardial ischemia. J Mol Cell Cardiol. 1984 May; 16(5):389-94. PMID: 6737481.
    Citations: 37     Fields:    Translation:AnimalsCells
  104. Kléber AG. [Basic principles of tachycardia arrhythmias]. Schweiz Rundsch Med Prax. 1984 Jan 17; 73(3):55-8. PMID: 6701413.
    Citations:    Fields:    Translation:Humans
  105. Kléber AG. Resting membrane potential, extracellular potassium activity, and intracellular sodium activity during acute global ischemia in isolated perfused guinea pig hearts. Circ Res. 1983 Apr; 52(4):442-50. PMID: 6831660.
    Citations: 68     Fields:    Translation:Animals
  106. Janse MJ, Kléber AG. Electrophysiological changes and ventricular arrhythmias in the early phase of regional myocardial ischemia. Circ Res. 1981 Nov; 49(5):1069-81. PMID: 7028311.
    Citations: 43     Fields:    Translation:Animals
  107. Janse MJ, van Capelle FJ, Morsink H, Kléber AG, Wilms-Schopman F, Cardinal R, d'Alnoncourt CN, Durrer D. Flow of "injury" current and patterns of excitation during early ventricular arrhythmias in acute regional myocardial ischemia in isolated porcine and canine hearts. Evidence for two different arrhythmogenic mechanisms. Circ Res. 1980 Aug; 47(2):151-65. PMID: 7397948.
    Citations: 75     Fields:    Translation:Animals
  108. Janse MJ, Cinca J, Moréna H, Fiolet JW, Kléber AG, de Vries GP, Becker AE, Durrer D. The "border zone" in myocardial ischemia. An electrophysiological, metabolic, and histochemical correlation in the pig heart. Circ Res. 1979 Apr; 44(4):576-88. PMID: 428053.
    Citations: 26     Fields:    Translation:Animals
  109. Kléber AG, Janse MJ, van Capelle FJ, Durrer D. Mechanism and time course of S-T and T-Q segment changes during acute regional myocardial ischemia in the pig heart determined by extracellular and intracellular recordings. Circ Res. 1978 May; 42(5):603-13. PMID: 639183.
    Citations: 53     Fields:    Translation:Animals
  110. Kléber AG, Janse MJ, Downar E, Durrer D. [Change in the TQ and ST/T segments in the electrocardiogram and its relationship to ventricular arrhythmias during acute transmural ischemia]. Schweiz Med Wochenschr. 1977 Nov 26; 107(47):1700-5. PMID: 73217.
    Citations:    Fields:    Translation:HumansAnimals
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.