Harvard Catalyst Profiles

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Rohit N. Kulkarni, Ph.D., M.D.

Co-Author

This page shows the publications co-authored by Rohit Kulkarni and C. Kahn.
Connection Strength

4.206
  1. Ephs and ephrins keep pancreatic Beta cells connected. Cell. 2007 Apr 20; 129(2):241-3.
    View in: PubMed
    Score: 0.369
  2. PDX-1 haploinsufficiency limits the compensatory islet hyperplasia that occurs in response to insulin resistance. J Clin Invest. 2004 Sep; 114(6):828-36.
    View in: PubMed
    Score: 0.307
  3. Molecular biology. HNFs--linking the liver and pancreatic islets in diabetes. Science. 2004 Feb 27; 303(5662):1311-2.
    View in: PubMed
    Score: 0.296
  4. Impact of genetic background on development of hyperinsulinemia and diabetes in insulin receptor/insulin receptor substrate-1 double heterozygous mice. Diabetes. 2003 Jun; 52(6):1528-34.
    View in: PubMed
    Score: 0.282
  5. beta-cell-specific deletion of the Igf1 receptor leads to hyperinsulinemia and glucose intolerance but does not alter beta-cell mass. Nat Genet. 2002 May; 31(1):111-5.
    View in: PubMed
    Score: 0.260
  6. Differential roles of FOXO transcription factors on insulin action in brown and white adipose tissue. J Clin Invest. 2021 Aug 24.
    View in: PubMed
    Score: 0.249
  7. Knockout mice challenge our concepts of glucose homeostasis and the pathogenesis of diabetes mellitus. J Pediatr Endocrinol Metab. 2000; 13 Suppl 6:1377-84.
    View in: PubMed
    Score: 0.222
  8. Altered function of insulin receptor substrate-1-deficient mouse islets and cultured beta-cell lines. J Clin Invest. 1999 Dec; 104(12):R69-75.
    View in: PubMed
    Score: 0.221
  9. Tissue-specific knockout of the insulin receptor in pancreatic beta cells creates an insulin secretory defect similar to that in type 2 diabetes. Cell. 1999 Feb 05; 96(3):329-39.
    View in: PubMed
    Score: 0.209
  10. Adipocyte Dynamics and Reversible Metabolic Syndrome in Mice with an Inducible Adipocyte-Specific Deletion of the Insulin Receptor. Cell Metab. 2017 02 07; 25(2):448-462.
    View in: PubMed
    Score: 0.181
  11. Differential Roles of Insulin and IGF-1 Receptors in Adipose Tissue Development and Function. Diabetes. 2016 08; 65(8):2201-13.
    View in: PubMed
    Score: 0.173
  12. p85a deficiency protects ß-cells from endoplasmic reticulum stress-induced apoptosis. Proc Natl Acad Sci U S A. 2014 Jan 21; 111(3):1192-7.
    View in: PubMed
    Score: 0.147
  13. Absence of diabetes and pancreatic exocrine dysfunction in a transgenic model of carboxyl-ester lipase-MODY (maturity-onset diabetes of the young). PLoS One. 2013; 8(4):e60229.
    View in: PubMed
    Score: 0.139
  14. New role of bone morphogenetic protein 7 in brown adipogenesis and energy expenditure. Nature. 2008 Aug 21; 454(7207):1000-4.
    View in: PubMed
    Score: 0.101
  15. Total insulin and IGF-I resistance in pancreatic beta cells causes overt diabetes. Nat Genet. 2006 May; 38(5):583-8.
    View in: PubMed
    Score: 0.086
  16. Loss of ARNT/HIF1beta mediates altered gene expression and pancreatic-islet dysfunction in human type 2 diabetes. Cell. 2005 Aug 12; 122(3):337-49.
    View in: PubMed
    Score: 0.082
  17. Glucose homeostasis and tissue transcript content of insulin signaling intermediates in four inbred strains of mice: C57BL/6, C57BLKS/6, DBA/2, and 129X1. Endocrinology. 2004 Jul; 145(7):3307-23.
    View in: PubMed
    Score: 0.074
  18. Identification of interactive loci linked to insulin and leptin in mice with genetic insulin resistance. Diabetes. 2003 Jun; 52(6):1535-43.
    View in: PubMed
    Score: 0.070
  19. Lipoatrophic diabetes in Irs1(-/-)/Irs3(-/-) double knockout mice. Genes Dev. 2002 Dec 15; 16(24):3213-22.
    View in: PubMed
    Score: 0.068
  20. Knockout models are useful tools to dissect the pathophysiology and genetics of insulin resistance. Clin Endocrinol (Oxf). 2002 Jul; 57(1):1-9.
    View in: PubMed
    Score: 0.066
  21. Comprehensive Search for Novel Circulating miRNAs and Axon Guidance Pathway Proteins Associated with Risk of ESKD in Diabetes. J Am Soc Nephrol. 2021 Sep; 32(9):2331-2351.
    View in: PubMed
    Score: 0.061
  22. Evidence for a circulating islet cell growth factor in insulin-resistant states. Proc Natl Acad Sci U S A. 2001 Jun 19; 98(13):7475-80.
    View in: PubMed
    Score: 0.061
  23. A model to explore the interaction between muscle insulin resistance and beta-cell dysfunction in the development of type 2 diabetes. Diabetes. 2000 Dec; 49(12):2126-34.
    View in: PubMed
    Score: 0.059
  24. Loss of insulin signaling in hepatocytes leads to severe insulin resistance and progressive hepatic dysfunction. Mol Cell. 2000 Jul; 6(1):87-97.
    View in: PubMed
    Score: 0.058
  25. Attenuation of PKCd enhances metabolic activity and promotes expansion of blood progenitors. EMBO J. 2018 12 14; 37(24).
    View in: PubMed
    Score: 0.051
  26. Insulin augmentation of glucose-stimulated insulin secretion is impaired in insulin-resistant humans. Diabetes. 2012 Feb; 61(2):301-9.
    View in: PubMed
    Score: 0.032
  27. Class IA phosphatidylinositol 3-kinase in pancreatic ß cells controls insulin secretion by multiple mechanisms. Cell Metab. 2010 Dec 01; 12(6):619-32.
    View in: PubMed
    Score: 0.030
  28. Pancreatic function in carboxyl-ester lipase knockout mice. Pancreatology. 2010; 10(4):467-76.
    View in: PubMed
    Score: 0.029
  29. Hypoxia-inducible factor-1alpha regulates beta cell function in mouse and human islets. J Clin Invest. 2010 Jun; 120(6):2171-83.
    View in: PubMed
    Score: 0.028
  30. Insulin enhances glucose-stimulated insulin secretion in healthy humans. Proc Natl Acad Sci U S A. 2010 Mar 09; 107(10):4770-5.
    View in: PubMed
    Score: 0.028
  31. A patient with type B insulin resistance syndrome, responsive to immune therapy. Nat Clin Pract Endocrinol Metab. 2007 Dec; 3(12):835-40.
    View in: PubMed
    Score: 0.024
  32. Skeletal muscle-selective knockout of LKB1 increases insulin sensitivity, improves glucose homeostasis, and decreases TRB3. Mol Cell Biol. 2006 Nov; 26(22):8217-27.
    View in: PubMed
    Score: 0.022
  33. Regulation of vascular endothelial growth factor expression and vascularization in the myocardium by insulin receptor and PI3K/Akt pathways in insulin resistance and ischemia. Arterioscler Thromb Vasc Biol. 2006 Apr; 26(4):787-93.
    View in: PubMed
    Score: 0.021
  34. Targeted elimination of peroxisome proliferator-activated receptor gamma in beta cells leads to abnormalities in islet mass without compromising glucose homeostasis. Mol Cell Biol. 2003 Oct; 23(20):7222-9.
    View in: PubMed
    Score: 0.018
  35. Reduced beta-cell mass and altered glucose sensing impair insulin-secretory function in betaIRKO mice. Am J Physiol Endocrinol Metab. 2004 Jan; 286(1):E41-9.
    View in: PubMed
    Score: 0.018
  36. Characterization of multiple signaling pathways of insulin in the regulation of vascular endothelial growth factor expression in vascular cells and angiogenesis. J Biol Chem. 2003 Aug 22; 278(34):31964-71.
    View in: PubMed
    Score: 0.018
  37. Effect of the insulin mimetic L-783,281 on intracellular Ca2+ and insulin secretion from pancreatic beta-cells. Diabetes. 2002 Feb; 51 Suppl 1:S43-9.
    View in: PubMed
    Score: 0.016
  38. Selective insulin signaling through A and B insulin receptors regulates transcription of insulin and glucokinase genes in pancreatic beta cells. Mol Cell. 2001 Mar; 7(3):559-70.
    View in: PubMed
    Score: 0.015
  39. Roles of insulin receptor substrate-1, phosphatidylinositol 3-kinase, and release of intracellular Ca2+ stores in insulin-stimulated insulin secretion in beta -cells. J Biol Chem. 2000 Jul 21; 275(29):22331-8.
    View in: PubMed
    Score: 0.014
Connection Strength
The connection strength for co-authors is the sum of the scores for each of their shared publications.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.