Harvard Catalyst Profiles

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Yubao Wang, Ph.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Wang Y, Manokaran C, Wu S, Roberts TM. The Mediator captures CDK7, an attractive transcriptional target in cancer. Cancer Cell. 2021 09 13; 39(9):1184-1186. PMID: 34416166.
    Citations:    Fields:    Translation:HumansAnimalsCells
  2. Zarei M, Du H, Nassar AH, Yan RE, Giannikou K, Johnson SH, Lam HC, Henske EP, Wang Y, Zhang T, Asara J, Kwiatkowski DJ. Tumors with TSC mutations are sensitive to CDK7 inhibition through NRF2 and glutathione depletion. J Exp Med. 2019 11 04; 216(11):2635-2652. PMID: 31506280; PMCID: PMC6829598.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  3. Sun B, Mason S, Wilson RC, Hazard SE, Wang Y, Fang R, Wang Q, Yeh ES, Yang M, Roberts TM, Zhao JJ, Wang Q. Inhibition of the transcriptional kinase CDK7 overcomes therapeutic resistance in HER2-positive breast cancers. Oncogene. 2020 01; 39(1):50-63. PMID: 31462705.
    Citations: 15     Fields:    Translation:HumansCells
  4. Wang Y, Li BB, Li J, Roberts TM, Zhao JJ. A Conditional Dependency on MELK for the Proliferation of Triple-Negative Breast Cancer Cells. iScience. 2018 Nov 30; 9:149-160. PMID: 30391850; PMCID: PMC6215964.
    Citations: 8     
  5. Wang Y, Begley M, Li Q, Huang HT, Lako A, Eck MJ, Gray NS, Mitchison TJ, Cantley LC, Zhao JJ. Mitotic MELK-eIF4B signaling controls protein synthesis and tumor cell survival. Proc Natl Acad Sci U S A. 2016 08 30; 113(35):9810-5. PMID: 27528663; PMCID: PMC5024598.
    Citations: 33     Fields:    Translation:HumansAnimalsCells
  6. Wang Y, Zhang T, Kwiatkowski N, Abraham BJ, Lee TI, Xie S, Yuzugullu H, Von T, Li H, Lin Z, Stover DG, Lim E, Wang ZC, Iglehart JD, Young RA, Gray NS, Zhao JJ. CDK7-dependent transcriptional addiction in triple-negative breast cancer. Cell. 2015 Sep 24; 163(1):174-86. PMID: 26406377.
    Citations: 183     Fields:    Translation:HumansAnimalsCells
  7. Wang Y, Lee YM, Baitsch L, Huang A, Xiang Y, Tong H, Lako A, Von T, Choi C, Lim E, Min J, Li L, Stegmeier F, Schlegel R, Eck MJ, Gray NS, Mitchison TJ, Zhao JJ. MELK is an oncogenic kinase essential for mitotic progression in basal-like breast cancer cells. Elife. 2014 May 20; 3:e01763. PMID: 24844244; PMCID: PMC4059381.
    Citations: 59     Fields:    Translation:HumansAnimalsCells
  8. Wang Y, Karnataki A, Parsons M, Weiss LM, Orlofsky A. 3-Methyladenine blocks Toxoplasma gondii division prior to centrosome replication. Mol Biochem Parasitol. 2010 Oct; 173(2):142-53. PMID: 20609430.
    Citations: 13     Fields:    Translation:AnimalsCells
  9. Wang Y, Weiss LM, Orlofsky A. Coordinate control of host centrosome position, organelle distribution, and migratory response by Toxoplasma gondii via host mTORC2. J Biol Chem. 2010 May 14; 285(20):15611-15618. PMID: 20236941; PMCID: PMC2865287.
    Citations: 18     Fields:    Translation:HumansAnimalsCells
  10. Deng L, Zhou JF, Sellers RS, Li JF, Nguyen AV, Wang Y, Orlofsky A, Liu Q, Hume DA, Pollard JW, Augenlicht L, Lin EY. A novel mouse model of inflammatory bowel disease links mammalian target of rapamycin-dependent hyperproliferation of colonic epithelium to inflammation-associated tumorigenesis. Am J Pathol. 2010 Feb; 176(2):952-67. PMID: 20042677; PMCID: PMC2808099.
    Citations: 102     Fields:    Translation:HumansAnimalsCells
  11. Wang Y, Weiss LM, Orlofsky A. Intracellular parasitism with Toxoplasma gondii stimulates mammalian-target-of-rapamycin-dependent host cell growth despite impaired signalling to S6K1 and 4E-BP1. Cell Microbiol. 2009 Jun; 11(6):983-1000. PMID: 19302577; PMCID: PMC2880858.
    Citations: 19     Fields:    Translation:HumansAnimalsCells
  12. Wang Y, Weiss LM, Orlofsky A. Host cell autophagy is induced by Toxoplasma gondii and contributes to parasite growth. J Biol Chem. 2009 Jan 16; 284(3):1694-701. PMID: 19028680; PMCID: PMC2615531.
    Citations: 66     Fields:    Translation:HumansAnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.