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Tianhong Dai, Ph.D.

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Biography
2009
Bullock-Wellman Fellowship Award, Massachusetts General Hospital/Harvard Medical School
2011
Extremity Trauma Research Award, Airlift Research Foundation
2012
Member Research Grant Award, Orthopaedic Trauma Association
2012
ECOR Deliberative Interim Support Fund, Massachusetts General Hospital
2013
CIMIT-DoD Award, Center for the Integration of Medicine and Technology & Department of Defense
2013
ECOR Deliberative Interim Support Fund, Massachusetts General Hospital
2014
ASLMS Research Grant, American Society for Laser Medicine and Surgery
2014
Smith Infectious Disease Foundation Research Grant Award, Smith Infectious Disease Foundation
2014
NIH Exploratory/Developmental Research Grant Award (R21), National Institutes of Health
2014
CIMIT-DoD Award, Center for the Integration of Medicine and Technology & Department of Defense
2016
Member Research Grant Award, Orthopaedic Trauma Association
2016
Military Medical Photonics Program Grant, Department of Defense
2016
NIH Research Project Grant (R01), National Institutes of Health
2017
Military Medical Photonics Program Grant, Department of Defense
2019
NIH Conference Grant Award (R13), National Institutes of Health
2020
Military Medical Photonics Program Grant, Department of Defense
2020
NIH Conference Grant Award (R13), National Institutes of Health
2021
ECOR Interim Support Fund, Massachusetts General Hospital

Overview

Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R13AI150097 (DAI, TIANHONG) Feb 1, 2020 - Jan 31, 2021
    NIH
    Photonic Diagnosis, Monitoring, Prevention, and Treatment of Infectious Diseases
    Role: Principal Investigator
  2. R13AI143109 (DAI, TIANHONG) Feb 1, 2019 - Jan 31, 2020
    NIH/NIAID
    Photonic diagnosis and treatment of infections and inflammatory diseases
    Role: Principal Investigator
  3. R01AI123312 (DAI, TIANHONG) Mar 1, 2016 - Feb 28, 2021
    NIH
    Antimicrobial blue light inactivation of pathogenic microbes
    Role: Principal Investigator
  4. R21AI109172 (DAI, TIANHONG) Jun 1, 2014 - Aug 31, 2016
    NIH
    Blue light for drug resistant skin and soft tissue infections
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Leanse LG, Dos Anjos C, Wang Y, Murray CK, Hooper DC, Dai T. Effective treatment of cutaneous mold infections by antimicrobial blue light that is potentiated by quinine. J Infect Dis. 2021 Feb 02. PMID: 33528496.
    Citations:    Fields:    
  2. Leanse LG, Zeng X, Dai T. Potentiated antimicrobial blue light killing of methicillin resistant Staphylococcus aureus by pyocyanin. J Photochem Photobiol B. 2021 Feb; 215:112109. PMID: 33486397.
    Citations:    Fields:    
  3. Lu M, Wang S, Wang T, Hu S, Bhayana B, Ishii M, Kong Y, Cai Y, Dai T, Cui W, Wu MX. Bacteria-specific phototoxic reactions triggered by blue light and phytochemical carvacrol. Sci Transl Med. 2021 Jan 06; 13(575). PMID: 33408183.
    Citations:    Fields:    
  4. Wu M, Rubin AE, Dai T, Schloss R, Usta OB, Golberg A, Yarmush M. High-Voltage, Pulsed Electric Fields Eliminate Pseudomonas aeruginosa Stable Infection in a Mouse Burn Model. Adv Wound Care (New Rochelle). 2020 Dec 18. PMID: 33066719.
    Citations:    
  5. Gao J, Wang S, Dong X, Leanse LG, Dai T, Wang Z. Co-delivery of resolvin D1 and antibiotics with nanovesicles to lungs resolves inflammation and clears bacteria in mice. Commun Biol. 2020 Nov 16; 3(1):680. PMID: 33199819.
    Citations: 2     
  6. Sabino CP, Ball AR, Baptista MS, Dai T, Hamblin MR, Ribeiro MS, Santos AL, Sellera FP, Tegos GP, Wainwright M. Light-based technologies for management of COVID-19 pandemic crisis. J Photochem Photobiol B. 2020 Nov; 212:111999. PMID: 32855026.
    Citations: 2     Fields:    Translation:HumansCellsPHPublic Health
  7. Magana M, Pushpanathan M, Santos AL, Leanse L, Fernandez M, Ioannidis A, Giulianotti MA, Apidianakis Y, Bradfute S, Ferguson AL, Cherkasov A, Seleem MN, Pinilla C, de la Fuente-Nunez C, Lazaridis T, Dai T, Houghten RA, Hancock REW, Tegos GP. The value of antimicrobial peptides in the age of resistance. Lancet Infect Dis. 2020 09; 20(9):e216-e230. PMID: 32653070.
    Citations: 27     Fields:    Translation:Cells
  8. Leanse LG, Goh XS, Cheng JX, Hooper DC, Dai T. Dual-wavelength photo-killing of methicillin-resistant Staphylococcus aureus. JCI Insight. 2020 06 04; 5(11). PMID: 32493838.
    Citations: 2     Fields:    
  9. Liu X, Chang Q, Ferrer-Espada R, Leanse LG, Goh XS, Wang X, Gelfand JA, Dai T. Photoinactivation of Moraxella catarrhalis Using 405-nm Blue Light: Implications for the Treatment of Otitis Media. Photochem Photobiol. 2020 05; 96(3):611-617. PMID: 32105346.
    Citations: 1     Fields:    Translation:HumansCells
  10. Leanse LG, Dong PT, Goh XS, Lu M, Cheng JX, Hooper DC, Dai T. Quinine Enhances Photo-Inactivation of Gram-Negative Bacteria. J Infect Dis. 2020 02 03; 221(4):618-626. PMID: 31565732.
    Citations: 3     Fields:    Translation:AnimalsCells
  11. Leanse LG, Goh XS, Dai T. Quinine Improves the Fungicidal Effects of Antimicrobial Blue Light: Implications for the Treatment of Cutaneous Candidiasis. Lasers Surg Med. 2020 07; 52(6):569-575. PMID: 31746024.
    Citations:    Fields:    
  12. Ferrer-Espada R, Wang Y, Goh XS, Dai T. Antimicrobial Blue Light Inactivation of Microbial Isolates in Biofilms. Lasers Surg Med. 2020 06; 52(5):472-478. PMID: 31536154.
    Citations: 5     Fields:    
  13. Chu Z, Hu X, Wang X, Wu J, Dai T, Wang X. Inactivation of Cronobacter sakazakii by blue light illumination and the resulting oxidative damage to fatty acids. Can J Microbiol. 2019 Dec; 65(12):922-929. PMID: 31525298.
    Citations: 3     Fields:    Translation:Cells
  14. Lu M, Dai T, Hu S, Zhang Q, Bhayana B, Wang L, Wu MX. Antimicrobial blue light for decontamination of platelets during storage. J Biophotonics. 2020 01; 13(1):e201960021. PMID: 31407467.
    Citations:    Fields:    
  15. Wang Y, Ferrer-Espada R, Baglo Y, Goh XS, Held KD, Grad YH, Gu Y, Gelfand JA, Dai T. Photoinactivation of Neisseria gonorrhoeae: A Paradigm-Changing Approach for Combating Antibiotic-Resistant Gonococcal Infection. J Infect Dis. 2019 07 31; 220(5):873-881. PMID: 30629196.
    Citations: 5     Fields:    Translation:HumansCells
  16. Wang Y, Ferrer-Espada R, Baglo Y, Gu Y, Dai T. Antimicrobial Blue Light Inactivation of Neisseria gonorrhoeae: Roles of Wavelength, Endogenous Photosensitizer, Oxygen, and Reactive Oxygen Species. Lasers Surg Med. 2019 11; 51(9):815-823. PMID: 31157931.
    Citations: 3     Fields:    Translation:HumansCells
  17. Ferrer-Espada R, Liu X, Goh XS, Dai T. Antimicrobial Blue Light Inactivation of Polymicrobial Biofilms. Front Microbiol. 2019; 10:721. PMID: 31024499.
    Citations: 8     
  18. Dong PT, Mohammad H, Hui J, Leanse LG, Li J, Liang L, Dai T, Seleem MN, Cheng JX. Photolysis of Staphyloxanthin in Methicillin-Resistant Staphylococcus aureus Potentiates Killing by Reactive Oxygen Species. Adv Sci (Weinh). 2019 Jun 05; 6(11):1900030. PMID: 31179216.
    Citations: 6     
  19. Wu J, Chu Z, Ruan Z, Wang X, Dai T, Hu X. Changes of Intracellular Porphyrin, Reactive Oxygen Species, and Fatty Acids Profiles During Inactivation of Methicillin-Resistant Staphylococcus aureus by Antimicrobial Blue Light. Front Physiol. 2018; 9:1658. PMID: 30546315.
    Citations: 8     
  20. Leanse LG, Harrington OD, Fang Y, Ahmed I, Goh XS, Dai T. Evaluating the Potential for Resistance Development to Antimicrobial Blue Light (at 405 nm) in Gram-Negative Bacteria: In vitro and in vivo Studies. Front Microbiol. 2018; 9:2403. PMID: 30459719.
    Citations: 9     
  21. Lu M, Dai T, Murray CK, Wu MX. Bactericidal Property of Oregano Oil Against Multidrug-Resistant Clinical Isolates. Front Microbiol. 2018; 9:2329. PMID: 30344513.
    Citations: 13     
  22. Ahmed I, Fang Y, Lu M, Yan Q, El-Hussein A, Hamblin MR, Dai T. Recent Patents on Light-Based Anti-Infective Approaches. Recent Pat Antiinfect Drug Discov. 2018; 13(1):70-88. PMID: 29119936.
    Citations: 3     Fields:    Translation:Humans
  23. Wang Y, Ferrer-Espada R, Gu Y, Dai T. Antimicrobial Blue Light: An Alternative Therapeutic for Multidrug-Resistant Gonococcal Infections? MOJ Sol Photoenergy Syst. 2017; 1(2). PMID: 31435621.
    Citations:    
  24. Narita K, Asano K, Morimoto Y, Igarashi T, Hamblin MR, Dai T, Nakane A. Disinfection and healing effects of 222-nm UVC light on methicillin-resistant Staphylococcus aureus infection in mouse wounds. J Photochem Photobiol B. 2018 Jan; 178:10-18. PMID: 29101868.
    Citations: 10     Fields:    Translation:AnimalsCellsPHPublic Health
  25. Wang Y, Wang Y, Wang Y, Murray CK, Hamblin MR, Hooper DC, Dai T. Antimicrobial blue light inactivation of pathogenic microbes: State of the art. Drug Resist Updat. 2017 11; 33-35:1-22. PMID: 29145971.
    Citations: 38     Fields:    Translation:HumansAnimalsCells
  26. Dai T, Hamblin MR. Visible Blue Light is Capable of Inactivating Candida albicans and Other Fungal Species. Photomed Laser Surg. 2017 07; 35(7):345-346. PMID: 28613980.
    Citations: 5     Fields:    Translation:HumansAnimals
  27. Wang Y, Harrington OD, Wang Y, Murray CK, Hamblin MR, Dai T. In Vivo Investigation of Antimicrobial Blue Light Therapy for Multidrug-resistant Acinetobacter baumannii Burn Infections Using Bioluminescence Imaging. J Vis Exp. 2017 04 28; (122). PMID: 28518072.
    Citations: 5     Fields:    Translation:AnimalsCells
  28. Dai T. The antimicrobial effect of blue light: What are behind? Virulence. 2017 08 18; 8(6):649-652. PMID: 28051916.
    Citations: 11     Fields:    Translation:Humans
  29. Zhu H, Kochevar IE, Behlau I, Zhao J, Wang F, Wang Y, Sun X, Hamblin MR, Dai T. Antimicrobial Blue Light Therapy for Infectious Keratitis: Ex Vivo and In Vivo Studies. Invest Ophthalmol Vis Sci. 2017 01 01; 58(1):586-593. PMID: 28129422.
    Citations: 6     Fields:    Translation:AnimalsCells
  30. Kim M, An J, Kim KS, Choi M, Humar M, Kwok SJ, Dai T, Yun SH. Optical lens-microneedle array for percutaneous light delivery. Biomed Opt Express. 2016 Oct 01; 7(10):4220-4227. PMID: 27867727.
    Citations: 10     
  31. Zhang Y, Zhu Y, Chen J, Wang Y, Sherwood ME, Murray CK, Vrahas MS, Hooper DC, Hamblin MR, Dai T. Antimicrobial blue light inactivation of Candida albicans: In vitro and in vivo studies. Virulence. 2016 07 03; 7(5):536-45. PMID: 26909654.
    Citations: 23     Fields:    Translation:HumansAnimalsCells
  32. Amin RM, Bhayana B, Hamblin MR, Dai T. Antimicrobial blue light inactivation of Pseudomonas aeruginosa by photo-excitation of endogenous porphyrins: In vitro and in vivo studies. Lasers Surg Med. 2016 07; 48(5):562-8. PMID: 26891084.
    Citations: 33     Fields:    Translation:AnimalsCellsPHPublic Health
  33. Wang Y, Wu X, Chen J, Amin R, Lu M, Bhayana B, Zhao J, Murray CK, Hamblin MR, Hooper DC, Dai T. Antimicrobial Blue Light Inactivation of Gram-Negative Pathogens in Biofilms: In Vitro and In Vivo Studies. J Infect Dis. 2016 May 01; 213(9):1380-7. PMID: 26908743.
    Citations: 30     Fields:    Translation:AnimalsCellsPHPublic Health
  34. Zhang Y, Dai T, Wang M, Vecchio D, Chiang LY, Hamblin MR. Potentiation of antimicrobial photodynamic inactivation mediated by a cationic fullerene by added iodide: in vitro and in vivo studies. Nanomedicine (Lond). 2015 Mar; 10(4):603-14. PMID: 25723093.
    Citations: 31     Fields:    Translation:HumansAnimalsCells
  35. Zhang Y, Zhu Y, Gupta A, Huang Y, Murray CK, Vrahas MS, Sherwood ME, Baer DG, Hamblin MR, Dai T. Antimicrobial blue light therapy for multidrug-resistant Acinetobacter baumannii infection in a mouse burn model: implications for prophylaxis and treatment of combat-related wound infections. J Infect Dis. 2014 Jun 15; 209(12):1963-71. PMID: 24381206.
    Citations: 42     Fields:    Translation:AnimalsCells
  36. Gupta A, Avci P, Dai T, Huang YY, Hamblin MR. Ultraviolet Radiation in Wound Care: Sterilization and Stimulation. Adv Wound Care (New Rochelle). 2013 Oct; 2(8):422-437. PMID: 24527357.
    Citations: 22     
  37. Yin R, Dai T, Avci P, Jorge AE, de Melo WC, Vecchio D, Huang YY, Gupta A, Hamblin MR. Light based anti-infectives: ultraviolet C irradiation, photodynamic therapy, blue light, and beyond. Curr Opin Pharmacol. 2013 Oct; 13(5):731-62. PMID: 24060701.
    Citations: 38     Fields:    Translation:HumansAnimals
  38. de Melo WC, Avci P, de Oliveira MN, Gupta A, Vecchio D, Sadasivam M, Chandran R, Huang YY, Yin R, Perussi LR, Tegos GP, Perussi JR, Dai T, Hamblin MR. Photodynamic inactivation of biofilm: taking a lightly colored approach to stubborn infection. Expert Rev Anti Infect Ther. 2013 Jul; 11(7):669-93. PMID: 23879608.
    Citations: 29     Fields:    Translation:Humans
  39. Huang L, Wang M, Dai T, Sperandio FF, Huang YY, Xuan Y, Chiang LY, Hamblin MR. Antimicrobial photodynamic therapy with decacationic monoadducts and bisadducts of [70]fullerene: in vitro and in vivo studies. Nanomedicine (Lond). 2014 Feb; 9(2):253-66. PMID: 23738632.
    Citations: 17     Fields:    Translation:AnimalsCells
  40. Gupta A, Dai T, Hamblin MR. Effect of red and near-infrared wavelengths on low-level laser (light) therapy-induced healing of partial-thickness dermal abrasion in mice. Lasers Med Sci. 2014 Jan; 29(1):257-65. PMID: 23619627.
    Citations: 29     Fields:    Translation:Animals
  41. Tanaka M, Mroz P, Dai T, Huang L, Morimoto Y, Kinoshita M, Yoshihara Y, Shinomiya N, Seki S, Nemoto K, Hamblin MR. Linezolid and vancomycin decrease the therapeutic effect of methylene blue-photodynamic therapy in a mouse model of MRSA bacterial arthritis. Photochem Photobiol. 2013 May-Jun; 89(3):679-82. PMID: 23311407.
    Citations: 4     Fields:    Translation:AnimalsCells
  42. Dai T, Gupta A, Huang YY, Sherwood ME, Murray CK, Vrahas MS, Kielian T, Hamblin MR. Blue light eliminates community-acquired methicillin-resistant Staphylococcus aureus in infected mouse skin abrasions. Photomed Laser Surg. 2013 Nov; 31(11):531-8. PMID: 23406384.
    Citations: 33     Fields:    Translation:AnimalsCells
  43. Xuan W, Vatansever F, Huang L, Wu Q, Xuan Y, Dai T, Ando T, Xu T, Huang YY, Hamblin MR. Transcranial low-level laser therapy improves neurological performance in traumatic brain injury in mice: effect of treatment repetition regimen. PLoS One. 2013; 8(1):e53454. PMID: 23308226.
    Citations: 42     Fields:    Translation:AnimalsCells
  44. Dai T, Gupta A, Huang YY, Yin R, Murray CK, Vrahas MS, Sherwood ME, Tegos GP, Hamblin MR. Blue light rescues mice from potentially fatal Pseudomonas aeruginosa burn infection: efficacy, safety, and mechanism of action. Antimicrob Agents Chemother. 2013 Mar; 57(3):1238-45. PMID: 23262998.
    Citations: 52     Fields:    Translation:AnimalsCells
  45. Sperandio FF, Sharma SK, Wang M, Jeon S, Huang YY, Dai T, Nayka S, de Sousa SC, Chiang LY, Hamblin MR. Photoinduced electron-transfer mechanisms for radical-enhanced photodynamic therapy mediated by water-soluble decacationic C70 and C84O2 Fullerene Derivatives. Nanomedicine. 2013 May; 9(4):570-9. PMID: 23117043.
    Citations: 10     Fields:    Translation:HumansCells
  46. St Denis TG, Dai T, Hamblin MR. Killing bacterial spores with blue light: when innate resistance meets the power of light. Photochem Photobiol. 2013 Jan-Feb; 89(1):2-4. PMID: 22946878.
    Citations: 3     Fields:    Translation:Cells
  47. Vecchio D, Dai T, Huang L, Fantetti L, Roncucci G, Hamblin MR. Antimicrobial photodynamic therapy with RLP068 kills methicillin-resistant Staphylococcus aureus and improves wound healing in a mouse model of infected skin abrasion PDT with RLP068/Cl in infected mouse skin abrasion. J Biophotonics. 2013 Sep; 6(9):733-42. PMID: 22987338.
    Citations: 25     Fields:    Translation:AnimalsCells
  48. Dai T, Murray CK, Vrahas MS, Baer DG, Tegos GP, Hamblin MR. Ultraviolet C light for Acinetobacter baumannii wound infections in mice: potential use for battlefield wound decontamination? J Trauma Acute Care Surg. 2012 Sep; 73(3):661-7. PMID: 22929495.
    Citations: 8     Fields:    Translation:AnimalsCellsPHPublic Health
  49. Sharma SK, Mroz P, Dai T, Huang YY, St Denis TG, Hamblin MR. Photodynamic Therapy for Cancer and for Infections: What Is the Difference? Isr J Chem. 2012 Sep; 52(8-9):691-705. PMID: 23248387.
    Citations: 18     
  50. Baxter RM, Dai T, Kimball J, Wang E, Hamblin MR, Wiesmann WP, McCarthy SJ, Baker SM. Chitosan dressing promotes healing in third degree burns in mice: gene expression analysis shows biphasic effects for rapid tissue regeneration and decreased fibrotic signaling. J Biomed Mater Res A. 2013 Feb; 101(2):340-8. PMID: 22847951.
    Citations: 10     Fields:    Translation:AnimalsCells
  51. Dai T, Gupta A, Murray CK, Vrahas MS, Tegos GP, Hamblin MR. Blue light for infectious diseases: Propionibacterium acnes, Helicobacter pylori, and beyond? Drug Resist Updat. 2012 Aug; 15(4):223-36. PMID: 22846406.
    Citations: 73     Fields:    Translation:HumansAnimalsCells
  52. Tanaka M, Mroz P, Dai T, Huang L, Morimoto Y, Kinoshita M, Yoshihara Y, Nemoto K, Shinomiya N, Seki S, Hamblin MR. Photodynamic therapy can induce a protective innate immune response against murine bacterial arthritis via neutrophil accumulation. PLoS One. 2012; 7(6):e39823. PMID: 22761911.
    Citations: 15     Fields:    Translation:AnimalsCells
  53. Dai T, Garcia B, Murray CK, Vrahas MS, Hamblin MR. UVC light prophylaxis for cutaneous wound infections in mice. Antimicrob Agents Chemother. 2012 Jul; 56(7):3841-8. PMID: 22564833.
    Citations: 15     Fields:    Translation:AnimalsCells
  54. Dai T, Fuchs BB, Coleman JJ, Prates RA, Astrakas C, St Denis TG, Ribeiro MS, Mylonakis E, Hamblin MR, Tegos GP. Concepts and principles of photodynamic therapy as an alternative antifungal discovery platform. Front Microbiol. 2012; 3:120. PMID: 22514547.
    Citations: 37     
  55. Huang YY, Sharma SK, Dai T, Chung H, Yaroslavsky A, Garcia-Diaz M, Chang J, Chiang LY, Hamblin MR. Can nanotechnology potentiate photodynamic therapy? Nanotechnol Rev. 2012 Mar; 1(2):111-146. PMID: 26361572.
    Citations: 26     
  56. Vera DM, Haynes MH, Ball AR, Dai T, Astrakas C, Kelso MJ, Hamblin MR, Tegos GP. Strategies to potentiate antimicrobial photoinactivation by overcoming resistant phenotypes. Photochem Photobiol. 2012 May-Jun; 88(3):499-511. PMID: 22242675.
    Citations: 20     Fields:    Translation:HumansAnimalsCells
  57. Dai T, Vrahas MS, Murray CK, Hamblin MR. Ultraviolet C irradiation: an alternative antimicrobial approach to localized infections? Expert Rev Anti Infect Ther. 2012 Feb; 10(2):185-95. PMID: 22339192.
    Citations: 41     Fields:    Translation:HumansAnimalsCells
  58. Chung H, Dai T, Sharma SK, Huang YY, Carroll JD, Hamblin MR. The nuts and bolts of low-level laser (light) therapy. Ann Biomed Eng. 2012 Feb; 40(2):516-33. PMID: 22045511.
    Citations: 217     Fields:    Translation:HumansAnimals
  59. St Denis TG, Dai T, Izikson L, Astrakas C, Anderson RR, Hamblin MR, Tegos GP. All you need is light: antimicrobial photoinactivation as an evolving and emerging discovery strategy against infectious disease. Virulence. 2011 Nov-Dec; 2(6):509-20. PMID: 21971183.
    Citations: 47     Fields:    Translation:HumansAnimalsCells
  60. Tanaka M, Kinoshita M, Yoshihara Y, Shinomiya N, Seki S, Nemoto K, Hirayama T, Dai T, Huang L, Hamblin MR, Morimoto Y. Optimal photosensitizers for photodynamic therapy of infections should kill bacteria but spare neutrophils. Photochem Photobiol. 2012 Jan-Feb; 88(1):227-32. PMID: 21950417.
    Citations: 18     Fields:    Translation:HumansAnimalsCells
  61. Ando T, Xuan W, Xu T, Dai T, Sharma SK, Kharkwal GB, Huang YY, Wu Q, Whalen MJ, Sato S, Obara M, Hamblin MR. Comparison of therapeutic effects between pulsed and continuous wave 810-nm wavelength laser irradiation for traumatic brain injury in mice. PLoS One. 2011; 6(10):e26212. PMID: 22028832.
    Citations: 43     Fields:    Translation:Animals
  62. Dai T, Bil de Arce VJ, Tegos GP, Hamblin MR. Blue dye and red light, a dynamic combination for prophylaxis and treatment of cutaneous Candida albicans infections in mice. Antimicrob Agents Chemother. 2011 Dec; 55(12):5710-7. PMID: 21930868.
    Citations: 29     Fields:    Translation:HumansAnimals
  63. Kharkwal GB, Sharma SK, Huang YY, Dai T, Hamblin MR. Photodynamic therapy for infections: clinical applications. Lasers Surg Med. 2011 Sep; 43(7):755-67. PMID: 22057503.
    Citations: 79     Fields:    Translation:Humans
  64. Dai T, Tanaka M, Huang YY, Hamblin MR. Chitosan preparations for wounds and burns: antimicrobial and wound-healing effects. Expert Rev Anti Infect Ther. 2011 Jul; 9(7):857-79. PMID: 21810057.
    Citations: 108     Fields:    Translation:HumansAnimalsCells
  65. Dai T, Kharkwal GB, Tanaka M, Huang YY, Bil de Arce VJ, Hamblin MR. Animal models of external traumatic wound infections. Virulence. 2011 Jul-Aug; 2(4):296-315. PMID: 21701256.
    Citations: 38     Fields:    Translation:HumansAnimals
  66. Mroz P, Xia Y, Asanuma D, Konopko A, Zhiyentayev T, Huang YY, Sharma SK, Dai T, Khan UJ, Wharton T, Hamblin MR. Intraperitoneal photodynamic therapy mediated by a fullerene in a mouse model of abdominal dissemination of colon adenocarcinoma. Nanomedicine. 2011 Dec; 7(6):965-74. PMID: 21645643.
    Citations: 19     Fields:    Translation:HumansAnimalsCells
  67. Huang L, Dai T, Xuan Y, Tegos GP, Hamblin MR. Synergistic combination of chitosan acetate with nanoparticle silver as a topical antimicrobial: efficacy against bacterial burn infections. Antimicrob Agents Chemother. 2011 Jul; 55(7):3432-8. PMID: 21502618.
    Citations: 37     Fields:    Translation:Animals
  68. Wainwright M, Dai T, Hamblin MR. Antimicrobial photodynamic therapy in the colon: delivering a light punch to the guts? Photochem Photobiol. 2011 Jul-Aug; 87(4):754-6. PMID: 21418077.
    Citations: 1     Fields:    Translation:HumansCells
  69. St Denis TG, Huang L, Dai T, Hamblin MR. Analysis of the bacterial heat shock response to photodynamic therapy-mediated oxidative stress. Photochem Photobiol. 2011 May-Jun; 87(3):707-13. PMID: 21261628.
    Citations: 10     Fields:    Translation:Cells
  70. Dai T, Kharkwal GB, Zhao J, St Denis TG, Wu Q, Xia Y, Huang L, Sharma SK, d'Enfert C, Hamblin MR. Ultraviolet-C light for treatment of Candida albicans burn infection in mice. Photochem Photobiol. 2011 Mar-Apr; 87(2):342-9. PMID: 21208209.
    Citations: 19     Fields:    Translation:HumansAnimalsCells
  71. Sharma SK, Dai T, Kharkwal GB, Huang YY, Huang L, De Arce VJ, Tegos GP, Hamblin MR. Drug discovery of antimicrobial photosensitizers using animal models. Curr Pharm Des. 2011; 17(13):1303-19. PMID: 21504410.
    Citations: 31     Fields:    Translation:HumansAnimals
  72. Lu Z, Dai T, Huang L, Kurup DB, Tegos GP, Jahnke A, Wharton T, Hamblin MR. Photodynamic therapy with a cationic functionalized fullerene rescues mice from fatal wound infections. Nanomedicine (Lond). 2010 Dec; 5(10):1525-33. PMID: 21143031.
    Citations: 42     Fields:    Translation:AnimalsCells
  73. Dai T, Tegos GP, St Denis TG, Anderson D, Sinofsky E, Hamblin MR. Ultraviolet-C irradiation for prevention of central venous catheter-related infections: an in vitro study. Photochem Photobiol. 2011 Jan-Feb; 87(1):250-5. PMID: 21073470.
    Citations: 5     Fields:    Translation:HumansPHPublic Health
  74. Ragàs X, Sánchez-García D, Ruiz-González R, Dai T, Agut M, Hamblin MR, Nonell S. Cationic porphycenes as potential photosensitizers for antimicrobial photodynamic therapy. J Med Chem. 2010 Nov 11; 53(21):7796-803. PMID: 20936792.
    Citations: 20     Fields:    Translation:AnimalsCells
  75. Katz TM, Glaich AS, Goldberg LH, Firoz BF, Dai T, Friedman PM. Treatment of melasma using fractional photothermolysis: a report of eight cases with long-term follow-up. Dermatol Surg. 2010 Aug; 36(8):1273-80. PMID: 20666816.
    Citations: 6     Fields:    Translation:Humans
  76. Ragàs X, Dai T, Tegos GP, Agut M, Nonell S, Hamblin MR. Photodynamic inactivation of Acinetobacter baumannii using phenothiazinium dyes: in vitro and in vivo studies. Lasers Surg Med. 2010 Jul; 42(5):384-90. PMID: 20583252.
    Citations: 29     Fields:    Translation:AnimalsCells
  77. Hamblin MR, Dai T. Can surgical site infections be treated by photodynamic therapy? Photodiagnosis Photodyn Ther. 2010 Jun; 7(2):134-6. PMID: 20510311.
    Citations: 8     Fields:    Translation:Humans
  78. Dai T, Huang YY, Sharma SK, Hashmi JT, Kurup DB, Hamblin MR. Topical antimicrobials for burn wound infections. Recent Pat Antiinfect Drug Discov. 2010 Jun; 5(2):124-51. PMID: 20429870.
    Citations: 42     Fields:    Translation:HumansAnimals
  79. Dai T, Tegos GP, Zhiyentayev T, Mylonakis E, Hamblin MR. Photodynamic therapy for methicillin-resistant Staphylococcus aureus infection in a mouse skin abrasion model. Lasers Surg Med. 2010 Jan; 42(1):38-44. PMID: 20077489.
    Citations: 70     Fields:    Translation:AnimalsCells
  80. Huang L, Dai T, Hamblin MR. Antimicrobial photodynamic inactivation and photodynamic therapy for infections. Methods Mol Biol. 2010; 635:155-73. PMID: 20552347.
    Citations: 27     Fields:    Translation:AnimalsCells
  81. Dai T, Huang YY, Hamblin MR. Photodynamic therapy for localized infections--state of the art. Photodiagnosis Photodyn Ther. 2009 Sep-Dec; 6(3-4):170-88. PMID: 19932449.
    Citations: 126     Fields:    Translation:Humans
  82. Dai T, Tegos GP, Lu Z, Huang L, Zhiyentayev T, Franklin MJ, Baer DG, Hamblin MR. Photodynamic therapy for Acinetobacter baumannii burn infections in mice. Antimicrob Agents Chemother. 2009 Sep; 53(9):3929-34. PMID: 19564369.
    Citations: 62     Fields:    Translation:AnimalsCells
  83. Dai T, Tegos GP, Burkatovskaya M, Castano AP, Hamblin MR. Chitosan acetate bandage as a topical antimicrobial dressing for infected burns. Antimicrob Agents Chemother. 2009 Feb; 53(2):393-400. PMID: 19015341.
    Citations: 28     Fields:    Translation:AnimalsCells
  84. Dai T, Tegos GP, Rolz-Cruz G, Cumbie WE, Hamblin MR. Ultraviolet C inactivation of dermatophytes: implications for treatment of onychomycosis. Br J Dermatol. 2008 Jun; 158(6):1239-46. PMID: 18410410.
    Citations: 12     Fields:    Translation:HumansAnimals
  85. Glaich AS, Goldberg LH, Dai T, Kunishige JH, Friedman PM. Fractional resurfacing: a new therapeutic modality for Becker's nevus. Arch Dermatol. 2007 Dec; 143(12):1488-90. PMID: 18086996.
    Citations: 8     Fields:    Translation:Humans
  86. Castano AP, Dai T, Yaroslavsky I, Cohen R, Apruzzese WA, Smotrich MH, Hamblin MR. Low-level laser therapy for zymosan-induced arthritis in rats: Importance of illumination time. Lasers Surg Med. 2007 Jul; 39(6):543-50. PMID: 17659584.
    Citations: 32     Fields:    Translation:Animals
  87. Glaich AS, Goldberg LH, Dai T, Friedman PM. Fractional photothermolysis for the treatment of telangiectatic matting: a case report. J Cosmet Laser Ther. 2007 Jun; 9(2):101-3. PMID: 17558760.
    Citations: 2     Fields:    Translation:Humans
  88. Dai T, Yaseen MA, Diagaradjane P, Chang DW, Anvari B. Comparative study of cryogen spray cooling with R-134a and R-404a: implications for laser treatment of dark human skin. J Biomed Opt. 2006 Jul-Aug; 11(4):041116. PMID: 16965144.
    Citations:    Fields:    Translation:HumansAnimalsPHPublic Health
  89. Behroozan DS, Goldberg LH, Dai T, Geronemus RG, Friedman PM. Fractional photothermolysis for the treatment of surgical scars: a case report. J Cosmet Laser Ther. 2006 Apr; 8(1):35-8. PMID: 16581684.
    Citations: 6     Fields:    Translation:Humans
  90. Behroozan DS, Goldberg LH, Glaich AS, Dai T, Friedman PM. Fractional photothermolysis for treatment of poikiloderma of civatte. Dermatol Surg. 2006 Feb; 32(2):298-301. PMID: 16442059.
    Citations: 8     Fields:    Translation:Humans
  91. Dai T, Diagaradjane P, Yaseen MA, Pikkula BM, Thomsen S, Anvari B. Laser-induced thermal injury to dermal blood vessels: analysis of wavelength (585 nm vs. 595 nm), cryogen spray cooling, and wound healing effects. Lasers Surg Med. 2005 Sep; 37(3):210-8. PMID: 16175632.
    Citations: 4     Fields:    Translation:Animals
  92. Pikkula BM, Chang DW, Dai T, Anvari B. Epidermal and vascular damage analysis of in vivo human skin in response to 595 nm pulsed laser irradiation. Lasers Surg Med. 2005 Jul; 37(1):19-28. PMID: 15971245.
    Citations:    Fields:    Translation:Humans
  93. Dai T, Pikkula BM, Wang LV, Anvari B. Comparison of human skin opto-thermal response to near-infrared and visible laser irradiations: a theoretical investigation. Phys Med Biol. 2004 Nov 07; 49(21):4861-77. PMID: 15584524.
    Citations: 9     Fields:    Translation:Humans
  94. Dai T, Pikkula BM, Tunnell JW, Chang DW, Anvari B. Thermal response of human skin epidermis to 595-nm laser irradiation at high incident dosages and long pulse durations in conjunction with cryogen spray cooling: an ex-vivo study. Lasers Surg Med. 2003; 33(1):16-24. PMID: 12866117.
    Citations: 7     Fields:    Translation:Humans
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.