Harvard Catalyst Profiles

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Ashwin N Ananthakrishnan, M.B.,B.S.

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Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R03DK112909 (ANANTHAKRISHNAN, ASHWIN N) Apr 15, 2017 - Mar 31, 2019
    NIH/NIDDK
    Genetic predictors of calprotectin response with anti-TNF and anti-integrin therapy in inflammatory bowel diseases
    Role: Principal Investigator
  2. K23DK097142 (ANANTHAKRISHNAN, ASHWIN N) Sep 15, 2012 - May 31, 2017
    NIH/NIDDK
    Genetic predictors of anti-TNF treatment response and infections in IBD
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Sheriff MZ, Mansoor E, Luther J, Ananthakrishnan AN, Abou Saleh M, Ho E, Briggs FBS, Dave M. Opportunistic Infections Are More Prevalent in Crohn's Disease and Ulcerative Colitis: A Large Population-Based Study. Inflamm Bowel Dis. 2020 Jan 06; 26(2):291-300. PMID: 31314891.
    Citations:    
  2. Yu A, Friedman S, Ananthakrishnan AN. Incidence and Predictors of Flares in the Postpartum Year Among Women With Inflammatory Bowel Disease. Inflamm Bowel Dis. 2020 Jan 02. PMID: 31895410.
    Citations:    
  3. Sasson AN, Ananthakrishnan AN, Raman M. Diet in treatment of Inflammatory Bowel Diseases. Clin Gastroenterol Hepatol. 2019 Dec 05. PMID: 31812656.
    Citations:    
  4. Cheng D, Chakrabortty A, Ananthakrishnan AN, Cai T. Estimating average treatment effects with a double-index propensity score. Biometrics. 2019 Dec 04. PMID: 31797368.
    Citations:    
  5. Zhang Y, Cai T, Yu S, Cho K, Hong C, Sun J, Huang J, Ho YL, Ananthakrishnan AN, Xia Z, Shaw SY, Gainer V, Castro V, Link N, Honerlaw J, Huang S, Gagnon D, Karlson EW, Plenge RM, Szolovits P, Savova G, Churchill S, O'Donnell C, Murphy SN, Gaziano JM, Kohane I, Cai T, Liao KP. High-throughput phenotyping with electronic medical record data using a common semi-supervised approach (PheCAP). Nat Protoc. 2019 Dec; 14(12):3426-3444. PMID: 31748751.
    Citations:    
  6. Cushing KC, Tan W, Alpers DH, Deshpande V, Ananthakrishnan AN. Complete histologic normalisation is associated with reduced risk of relapse among patients with ulcerative colitis in complete endoscopic remission. Aliment Pharmacol Ther. 2019 Nov 07. PMID: 31696961.
    Citations:    
  7. Long GH, Tatro AR, Oh YS, Reddy SR, Ananthakrishnan AN. Analysis of Safety, Medical Resource Utilization, and Treatment Costs by Drug Class for Management of Inflammatory Bowel Disease in the United States Based on Insurance Claims Data. Adv Ther. 2019 Nov; 36(11):3079-3095. PMID: 31562607.
    Citations:    
  8. Ma C, Sandborn WJ, D'Haens GR, Zou G, Stitt LW, Singh S, Ananthakrishnan AN, Dulai PS, Khanna R, Jairath V, Feagan BG. Discordance Between Patient-Reported Outcomes and Mucosal Inflammation in Patients With Mild to Moderate Ulcerative Colitis. Clin Gastroenterol Hepatol. 2019 Sep 20. PMID: 31546056.
    Citations:    
  9. Borren NZ, Tan W, Colizzo FP, Luther J, Garber JJ, Khalili H, van der Woude CJ, Ananthakrishnan AN. Longitudinal trajectory of fatigue with initiation of biologic therapy in inflammatory bowel diseases: A prospective cohort study. J Crohns Colitis. 2019 Aug 26. PMID: 31504365.
    Citations:    
  10. Borren NZ, Luther J, Colizzo FP, Garber JG, Khalili H, Ananthakrishnan AN. Low-dose Methotrexate has Similar Outcomes to High-dose Methotrexate in Combination with Anti-TNF Therapy in Inflammatory Bowel Diseases. J Crohns Colitis. 2019 Aug 14; 13(8):990-995. PMID: 30888405.
    Citations:    
  11. Ananthakrishnan AN, Cagan A, Cai T, Gainer VS, Savova G, Shaw SY, Churchill S, Burke KE, Karlson EW, Murphy SN, Kohane I, Liao KP, Xavier RJ. Use of Narrative Concepts in Electronic Health Records to Validate Associations Between Genetic Factors and Response to Treatment of Inflammatory Bowel Diseases. Clin Gastroenterol Hepatol. 2019 Aug 09. PMID: 31404664.
    Citations:    
  12. Burke KE, Nayor J, Campbell EJ, Ananthakrishnan AN, Khalili H, Richter JM. Interval Colorectal Cancer in Inflammatory Bowel Disease: The Role of Guideline Adherence. Dig Dis Sci. 2020 Jan; 65(1):111-118. PMID: 31367882.
    Citations:    
  13. Smillie CS, Biton M, Ordovas-Montanes J, Sullivan KM, Burgin G, Graham DB, Herbst RH, Rogel N, Slyper M, Waldman J, Sud M, Andrews E, Velonias G, Haber AL, Jagadeesh K, Vickovic S, Yao J, Stevens C, Dionne D, Nguyen LT, Villani AC, Hofree M, Creasey EA, Huang H, Rozenblatt-Rosen O, Garber JJ, Khalili H, Desch AN, Daly MJ, Ananthakrishnan AN, Shalek AK, Xavier RJ, Regev A. Intra- and Inter-cellular Rewiring of the Human Colon during Ulcerative Colitis. Cell. 2019 Jul 25; 178(3):714-730.e22. PMID: 31348891.
    Citations:    
  14. Faye AS, Wen T, Ananthakrishnan AN, Lichtiger S, Kaplan GG, Friedman AM, Lawlor G, Wright JD, Attenello FJ, Mack WJ, Lebwohl B. Acute Venous Thromboembolism Risk Highest Within 60 Days After Discharge From the Hospital in Patients With Inflammatory Bowel Diseases. Clin Gastroenterol Hepatol. 2019 Jul 20. PMID: 31336196.
    Citations:    
  15. Axelrad JE, Bazarbashi A, Zhou J, Castañeda D, Gujral A, Sperling D, Glass J, Agrawal M, Hong S, Lawlor G, Hudesman D, Chang S, Shah S, Yajnik V, Ananthakrishnan A, Khalili H, Colombel JF, Itzkowitz S. Hormone Therapy for Cancer Is a Risk Factor for Relapse of Inflammatory Bowel Diseases. Clin Gastroenterol Hepatol. 2019 Jul 11. PMID: 31302306.
    Citations:    
  16. Le Berre C, Ananthakrishnan AN, Danese S, Singh S, Peyrin-Biroulet L. Ulcerative Colitis and Crohn's Disease Have Similar Burden and Goals for Treatment. Clin Gastroenterol Hepatol. 2020 Jan; 18(1):14-23. PMID: 31301452.
    Citations:    
  17. Boden EK, Canavan JB, Moran CJ, McCann K, Dunn WA, Farraye FA, Ananthakrishnan AN, Yajnik V, Gandhi R, Nguyen DD, Bhan AK, Weiner HL, Korzenik JR, Snapper SB. Immunologic Alterations Associated With Oral Delivery of Anti-CD3 (OKT3) Monoclonal Antibodies in Patients With Moderate-to-Severe Ulcerative Colitis. Crohns Colitis 360. 2019 Jul; 1(2):otz009. PMID: 31423487.
    Citations:    
  18. Lloyd-Price J, Arze C, Ananthakrishnan AN, Schirmer M, Avila-Pacheco J, Poon TW, Andrews E, Ajami NJ, Bonham KS, Brislawn CJ, Casero D, Courtney H, Gonzalez A, Graeber TG, Hall AB, Lake K, Landers CJ, Mallick H, Plichta DR, Prasad M, Rahnavard G, Sauk J, Shungin D, Vázquez-Baeza Y, White RA, Braun J, Denson LA, Jansson JK, Knight R, Kugathasan S, McGovern DPB, Petrosino JF, Stappenbeck TS, Winter HS, Clish CB, Franzosa EA, Vlamakis H, Xavier RJ, Huttenhower C. Multi-omics of the gut microbial ecosystem in inflammatory bowel diseases. Nature. 2019 05; 569(7758):655-662. PMID: 31142855.
    Citations:    
  19. Ona S, James K, Ananthakrishnan AN, Long MD, Martin C, Chen W, Mitchell CM. Association Between Vulvovaginal Discomfort and Activity of Inflammatory Bowel Diseases. Clin Gastroenterol Hepatol. 2019 May 18. PMID: 31108226.
    Citations:    
  20. Liu PH, Lebwohl B, Burke KE, Ivey KL, Ananthakrishnan AN, Lochhead P, Olen O, Ludvigsson JF, Richter JM, Chan AT, Khalili H. Correction: Dietary Gluten Intake and Risk of Microscopic Colitis Among US Women Without Celiac Disease: A Prospective Cohort Study. Am J Gastroenterol. 2019 05; 114(5):837. PMID: 31082842.
    Citations:    
  21. Ananthakrishnan AN. Reply. Clin Gastroenterol Hepatol. 2019 Aug; 17(9):1919. PMID: 30965106.
    Citations:    
  22. Deepak P, Axelrad JE, Ananthakrishnan AN. The Role of the Radiologist in Determining Disease Severity in Inflammatory Bowel Diseases. Gastrointest Endosc Clin N Am. 2019 Jul; 29(3):447-470. PMID: 31078247.
    Citations:    
  23. Borren NZ, van der Woude CJ, Ananthakrishnan AN. Fatigue in IBD: epidemiology, pathophysiology and management. Nat Rev Gastroenterol Hepatol. 2019 04; 16(4):247-259. PMID: 30531816.
    Citations:    Fields:    
  24. Borren NZ, Khalili H, Luther J, Colizzo FP, Garber JJ, Ananthakrishnan AN. Second-Look Endoscopy in Hospitalized Severe Ulcerative Colitis: A Retrospective Cohort Study. Inflamm Bowel Dis. 2019 03 14; 25(4):750-755. PMID: 30204864.
    Citations:    Fields:    
  25. Rubin DT, Ananthakrishnan AN, Siegel CA, Sauer BG, Long MD. ACG Clinical Guideline: Ulcerative Colitis in Adults. Am J Gastroenterol. 2019 03; 114(3):384-413. PMID: 30840605.
    Citations:    
  26. Nazarenkov N, Seeger K, Beeken L, Ananthakrishnan AN, Khalili H, Lewis JD, Konijeti GG. Implementing Dietary Modifications and Assessing Nutritional Adequacy of Diets for Inflammatory Bowel Disease. Gastroenterol Hepatol (N Y). 2019 Mar; 15(3):133-144. PMID: 31061655.
    Citations:    
  27. Walker GJ, Harrison JW, Heap GA, Voskuil MD, Andersen V, Anderson CA, Ananthakrishnan AN, Barrett JC, Beaugerie L, Bewshea CM, Cole AT, Cummings FR, Daly MJ, Ellul P, Fedorak RN, Festen EAM, Florin TH, Gaya DR, Halfvarson J, Hart AL, Heerasing NM, Hendy P, Irving PM, Jones SE, Koskela J, Lindsay JO, Mansfield JC, McGovern D, Parkes M, Pollok RCG, Ramakrishnan S, Rampton DS, Rivas MA, Russell RK, Schultz M, Sebastian S, Seksik P, Singh A, So K, Sokol H, Subramaniam K, Todd A, Annese V, Weersma RK, Xavier R, Ward R, Weedon MN, Goodhand JR, Kennedy NA, Ahmad T. Association of Genetic Variants in NUDT15 With Thiopurine-Induced Myelosuppression in Patients With Inflammatory Bowel Disease. JAMA. 2019 02 26; 321(8):773-785. PMID: 30806694.
    Citations:    
  28. Cushing KC, Kordbacheh H, Gee MS, Kambadakone A, Ananthakrishnan AN. CT-Visualized Colonic Mural Stratification Independently Predicts the Need for Medical or Surgical Rescue Therapy in Hospitalized Ulcerative Colitis Patients. Dig Dis Sci. 2019 Aug; 64(8):2265-2272. PMID: 30796684.
    Citations:    
  29. Adar T, Faleck D, Sasidharan S, Cushing K, Borren NZ, Nalagatla N, Ungaro R, Sy W, Owen SC, Patel A, Cohen BL, Ananthakrishnan AN. Comparative safety and effectiveness of tumor necrosis factor a antagonists and vedolizumab in elderly IBD patients: a multicentre study. Aliment Pharmacol Ther. 2019 04; 49(7):873-879. PMID: 30773667.
    Citations:    
  30. Vedamurthy A, Ananthakrishnan AN. Influence of Environmental Factors in the Development and Outcomes of Inflammatory Bowel Disease. Gastroenterol Hepatol (N Y). 2019 Feb; 15(2):72-82. PMID: 31011301.
    Citations:    
  31. Ng SC, Ananthakrishnan AN. New approaches along the IBD course: diet, tight control and stem cells. Nat Rev Gastroenterol Hepatol. 2019 02; 16(2):82-84. PMID: 30464302.
    Citations:    Fields:    
  32. Lavoie S, Conway KL, Lassen KG, Jijon HB, Pan H, Chun E, Michaud M, Lang JK, Gallini Comeau CA, Dreyfuss JM, Glickman JN, Vlamakis H, Ananthakrishnan A, Kostic A, Garrett WS, Xavier RJ. The Crohn's disease polymorphism, ATG16L1 T300A, alters the gut microbiota and enhances the local Th1/Th17 response. Elife. 2019 01 22; 8. PMID: 30666959.
    Citations:    Fields:    
  33. Kelly CR, Ananthakrishnan AN. Manipulating the Microbiome With Fecal Transplantation to Treat Ulcerative Colitis. JAMA. 2019 01 15; 321(2):151-152. PMID: 30644970.
    Citations:    Fields:    
  34. Burke KE, Ananthakrishnan AN. Tofacitinib: A Jak of All Trades. Clin Gastroenterol Hepatol. 2019 Jul; 17(8):1438-1440. PMID: 30625401.
    Citations:    Fields:    
  35. Levy A, Borren NZ, Maxner B, Tan W, Bellavance D, Staller K, Chung D, Khalili H, Ananthakrishnan AN. Cancer risk in microscopic colitis: a retrospective cohort study. BMC Gastroenterol. 2019 Jan 05; 19(1):1. PMID: 30611218.
    Citations:    Fields:    Translation:Humans
  36. Lee GC, Deery SE, Kunitake H, Hicks CW, Olariu AG, Savitt LR, Ananthakrishnan AN, Ricciardi R, Hodin RA, Bordeianou LG. Comparable perioperative outcomes, long-term outcomes, and quality of life in a retrospective analysis of ulcerative colitis patients following 2-stage versus 3-stage proctocolectomy with ileal pouch-anal anastomosis. Int J Colorectal Dis. 2019 Mar; 34(3):491-499. PMID: 30610435.
    Citations:    Fields:    
  37. Borren NZ, Ananthakrishnan AN. Safety of Biologic Therapy in Older Patients With Immune-Mediated Diseases: A Systematic Review and Meta-analysis. Clin Gastroenterol Hepatol. 2019 Aug; 17(9):1736-1743.e4. PMID: 30616024.
    Citations:    Fields:    
  38. Liu PH, Lebwohl B, Burke KE, Ivey KL, Ananthakrishnan AN, Lochhead P, Olen O, Ludvigsson JF, Richter JM, Chan AT, Khalili H. Dietary Gluten Intake and Risk of Microscopic Colitis Among US Women without Celiac Disease: A Prospective Cohort Study. Am J Gastroenterol. 2019 01; 114(1):127-134. PMID: 30181535.
    Citations:    Fields:    
  39. Liu PH, Burke KE, Ananthakrishnan AN, Lochhead P, Olen O, Ludvigsson JF, Richter JM, Chan AT, Khalili H. Obesity and Weight Gain Since Early Adulthood Are Associated With a Lower Risk of Microscopic Colitis. Clin Gastroenterol Hepatol. 2019 Nov; 17(12):2523-2532.e1. PMID: 30529732.
    Citations:    Fields:    
  40. Barnes EL, Kochar B, Long MD, Pekow J, Ananthakrishnan A, Anyane-Yeboa A, Martin C, Galanko J, Herfarth HH, Kappelman MD, Sandler RS. Lack of Difference in Treatment Patterns and Clinical Outcomes Between Black and White Patients With Inflammatory Bowel Disease. Inflamm Bowel Dis. 2018 11 29; 24(12):2634-2640. PMID: 29788063.
    Citations:    Fields:    
  41. Cushing KC, Kordbacheh H, Gee MS, Kambadakone A, Ananthakrishnan AN. Reply to 'Comment on Sarcopenia is a Novel Predictor of the Need for Rescue Therapy in Hospitalized Ulcerative Colitis Patients'. J Crohns Colitis. 2018 Nov 09; 12(10):1256. PMID: 29939235.
    Citations:    Fields:    
  42. Ghorbani S, Chandradas S, Wayman C, Diamant J, Ananthakrishnan AN, Konijeti GG. Patient age determines adherence to preventive care measures among patients with ulcerative colitis. Dig Liver Dis. 2019 01; 51(1):178-179. PMID: 30503295.
    Citations:    Fields:    
  43. Ananthakrishnan AN, Singal AG, Chang L. The Gut Microbiome and Digestive Health - A New Frontier. Clin Gastroenterol Hepatol. 2019 01; 17(2):215-217. PMID: 30385328.
    Citations:    Fields:    
  44. de Silva PS, O'Toole A, Marc LG, Ulysse CA, Testa MA, Julsgaard M, Ngyuen D, Ananthakrishnan A, Laursen T, Højgaard A, Christensen LA, Korzenik J, Friedman S. Development of a Sexual Dysfunction Scale for Women With Inflammatory Bowel Disease. Inflamm Bowel Dis. 2018 10 12; 24(11):2350-2359. PMID: 30165525.
    Citations:    Fields:    
  45. Lindoso L, Mondal K, Venkateswaran S, Somineni HK, Ballengee C, Walters TD, Griffiths A, Noe JD, Crandall W, Snapper S, Rabizadeh S, Rosh JR, LeLeiko N, Guthery S, Mack D, Kellermayer R, Gulati AS, Pfefferkorn MD, Moulton DE, Keljo D, Cohen S, Oliva-Hemker M, Heyman MB, Otley A, Baker SS, Evans JS, Kirschner BS, Patel AS, Ziring D, Stephens MC, Baldassano R, Dubinsky MC, Markowitz J, Denson LA, Hyams J, Kugathasan S, Ananthakrishnan AN. The Effect of Early-Life Environmental Exposures on Disease Phenotype and Clinical Course of Crohn's Disease in Children. Am J Gastroenterol. 2018 10; 113(10):1524-1529. PMID: 30267029.
    Citations:    Fields:    
  46. Cai T, Lin TC, Bond A, Huang J, Kane-Wanger G, Cagan A, Murphy SN, Ananthakrishnan AN, Liao KP. The Association Between Arthralgia and Vedolizumab Using Natural Language Processing. Inflamm Bowel Dis. 2018 09 15; 24(10):2242-2246. PMID: 29846617.
    Citations:    Fields:    
  47. Simon TG, Van Der Sloot KWJ, Chin SB, Joshi AD, Lochhead P, Ananthakrishnan AN, Xavier R, Chung RT, Khalili H. IRGM Gene Variants Modify the Relationship Between Visceral Adipose Tissue and NAFLD in Patients With Crohn's Disease. Inflamm Bowel Dis. 2018 09 15; 24(10):2247-2257. PMID: 29788077.
    Citations:    Fields:    
  48. Khalili H, Chan SSM, Lochhead P, Ananthakrishnan AN, Hart AR, Chan AT. The role of diet in the aetiopathogenesis of inflammatory bowel disease. Nat Rev Gastroenterol Hepatol. 2018 09; 15(9):525-535. PMID: 29789682.
    Citations:    Fields:    
  49. Ananthakrishnan AN. Bugs and drugs: Predicting response to therapy. J Gastroenterol Hepatol. 2018 Sep; 33 Suppl 3:27. PMID: 30187562.
    Citations:    Fields:    
  50. Ananthakrishnan AN. Making sense of clinical predictors. J Gastroenterol Hepatol. 2018 Sep; 33 Suppl 3:7-8. PMID: 30187548.
    Citations:    Fields:    
  51. Ananthakrishnan AN. Debate session: So what causes inflammatory bowel disease? It's all in the environment. J Gastroenterol Hepatol. 2018 Sep; 33 Suppl 3:24. PMID: 30187567.
    Citations:    Fields:    
  52. Cushing KC, Kordbacheh H, Gee MS, Kambadakone A, Ananthakrishnan AN. Sarcopenia is a Novel Predictor of the Need for Rescue Therapy in Hospitalized Ulcerative Colitis Patients. J Crohns Colitis. 2018 Aug 29; 12(9):1036-1041. PMID: 29762697.
    Citations:    Fields:    
  53. Burke KE, Ananthakrishnan AN, Lochhead P, Liu PH, Olen O, Ludvigsson JF, Richter JM, Tworoger SS, Chan AT, Khalili H. Identification of Menopausal and Reproductive Risk Factors for Microscopic Colitis-Results From the Nurses' Health Study. Gastroenterology. 2018 12; 155(6):1764-1775.e2. PMID: 30144433.
    Citations:    Fields:    Translation:Humans
  54. Gurry T, Gibbons SM, Nguyen LTT, Kearney SM, Ananthakrishnan A, Jiang X, Duvallet C, Kassam Z, Alm EJ. Predictability and persistence of prebiotic dietary supplementation in a healthy human cohort. Sci Rep. 2018 08 23; 8(1):12699. PMID: 30139999.
    Citations:    Fields:    
  55. Takahashi MK, Tan X, Dy AJ, Braff D, Akana RT, Furuta Y, Donghia N, Ananthakrishnan A, Collins JJ. A low-cost paper-based synthetic biology platform for analyzing gut microbiota and host biomarkers. Nat Commun. 2018 08 21; 9(1):3347. PMID: 30131493.
    Citations:    Fields:    Translation:HumansCells
  56. Luther J, Gala MK, Borren N, Masia R, Goodman RP, Moeller IH, DiGiacomo E, Ehrlich A, Warren A, Yarmush ML, Ananthakrishnan A, Corey K, Kaplan LM, Bhatia S, Chung RT, Patel SJ. Hepatic connexin 32 associates with nonalcoholic fatty liver disease severity. Hepatol Commun. 2018 Jul; 2(7):786-797. PMID: 30202815.
    Citations:    
  57. Burke KE, Khalili H, Garber JJ, Haritunians T, McGovern DPB, Xavier RJ, Ananthakrishnan AN. Genetic Markers Predict Primary Nonresponse and Durable Response to Anti-Tumor Necrosis Factor Therapy in Ulcerative Colitis. Inflamm Bowel Dis. 2018 07 12; 24(8):1840-1848. PMID: 29718226.
    Citations:    Fields:    
  58. Ananthakrishnan AN, Ng SC. Reply. Clin Gastroenterol Hepatol. 2018 07; 16(7):1177. PMID: 29914642.
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  59. Vedamurthy A, Xu L, Luther J, Colizzo F, Garber JJ, Khalili H, Ananthakrishnan AN. Long-Term Outcomes of Immunosuppression-Naïve Steroid Responders Following Hospitalization for Ulcerative Colitis. Dig Dis Sci. 2018 10; 63(10):2740-2746. PMID: 29951797.
    Citations:    Fields:    Translation:Humans
  60. Nalagatla N, Falloon K, Tran G, Borren NZ, Avalos D, Luther J, Colizzo F, Garber J, Khalili H, Melia J, Bohm M, Ananthakrishnan AN. Effect of Accelerated Infliximab Induction on Short- and Long-term Outcomes of Acute Severe Ulcerative Colitis: A Retrospective Multicenter Study and Meta-analysis. Clin Gastroenterol Hepatol. 2019 02; 17(3):502-509.e1. PMID: 29944926.
    Citations:    Fields:    
  61. Chandradas S, Khalili H, Ananthakrishnan A, Wayman C, Reidel W, Waalen J, Konijeti GG. Does Obesity Influence the Risk of Clostridium difficile Infection Among Patients with Ulcerative Colitis? Dig Dis Sci. 2018 09; 63(9):2445-2450. PMID: 29779082.
    Citations:    Fields:    Translation:Humans
  62. Staller K, Barshop K, Kuo B, Ananthakrishnan AN. Depression but Not Symptom Severity is Associated With Work and School Absenteeism in Refractory Chronic Constipation. J Clin Gastroenterol. 2018 May/Jun; 52(5):407-412. PMID: 28059936.
    Citations:    Fields:    
  63. Burke KE, Ananthakrishnan AN, Lochhead P, Olen O, Ludvigsson JF, Richter JM, Chan AT, Khalili H. Smoking is Associated with an Increased Risk of Microscopic Colitis: Results From Two Large Prospective Cohort Studies of US Women. J Crohns Colitis. 2018 Apr 27; 12(5):559-567. PMID: 29370359.
    Citations:    Fields:    Translation:Humans
  64. Borren NZ, Conway G, Garber JJ, Khalili H, Budree S, Mallick H, Yajnik V, Xavier RJ, Ananthakrishnan AN. Differences in Clinical Course, Genetics, and the Microbiome Between Familial and Sporadic Inflammatory Bowel Diseases. J Crohns Colitis. 2018 Apr 27; 12(5):525-531. PMID: 29145572.
    Citations: 1     Fields:    Translation:Humans
  65. Ananthakrishnan AN, Martin C, Kane S, Sandler RS, Long MD. Paternal Disease Activity Is Associated With Difficulty in Conception Among Men With Inflammatory Bowel Diseases. Clin Gastroenterol Hepatol. 2019 01; 17(1):203-204. PMID: 29653290.
    Citations:    Fields:    
  66. Luther J, Gala M, Patel SJ, Dave M, Borren N, Xavier RJ, Ananthakrishnan AN. Loss of Response to Anti-Tumor Necrosis Factor Alpha Therapy in Crohn's Disease Is Not Associated with Emergence of Novel Inflammatory Pathways. Dig Dis Sci. 2018 03; 63(3):738-745. PMID: 29372477.
    Citations:    Fields:    Translation:Humans
  67. Schirmer M, Franzosa EA, Lloyd-Price J, McIver LJ, Schwager R, Poon TW, Ananthakrishnan AN, Andrews E, Barron G, Lake K, Prasad M, Sauk J, Stevens B, Wilson RG, Braun J, Denson LA, Kugathasan S, McGovern DPB, Vlamakis H, Xavier RJ, Huttenhower C. Dynamics of metatranscription in the inflammatory bowel disease gut microbiome. Nat Microbiol. 2018 03; 3(3):337-346. PMID: 29311644.
    Citations: 4     Fields:    
  68. Arora U, Ananthakrishnan AN, Kedia S, Bopanna S, Mouli PV, Yadav DP, Makharia GK, Yajnik V, Ahuja V. Effect of oral tobacco use and smoking on outcomes of Crohn's disease in India. J Gastroenterol Hepatol. 2018 Jan; 33(1):134-140. PMID: 28475826.
    Citations: 4     Fields:    Translation:Humans
  69. Yu S, Ma Y, Gronsbell J, Cai T, Ananthakrishnan AN, Gainer VS, Churchill SE, Szolovits P, Murphy SN, Kohane IS, Liao KP, Cai T. Enabling phenotypic big data with PheNorm. J Am Med Inform Assoc. 2018 01 01; 25(1):54-60. PMID: 29126253.
    Citations: 2     Fields:    Translation:Humans
  70. Staller K, Barshop K, Ananthakrishnan AN, Kuo B. Number of retained radiopaque markers on a colonic transit study does not correlate with symptom severity or quality of life in chronic constipation. Neurogastroenterol Motil. 2018 05; 30(5):e13269. PMID: 29251404.
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  71. Feathers A, Swaminath A, Ananthakrishnan AN, Falzon L, Li Ferry S. Letter: reproducible evidence shows that exclusive enteral nutrition significantly reduces faecal calprotectin concentrations in children with active Crohn's disease-Authors' reply. Aliment Pharmacol Ther. 2017 12; 46(11-12):1121. PMID: 29105134.
    Citations:    Fields:    Translation:Humans
  72. Hall AB, Yassour M, Sauk J, Garner A, Jiang X, Arthur T, Lagoudas GK, Vatanen T, Fornelos N, Wilson R, Bertha M, Cohen M, Garber J, Khalili H, Gevers D, Ananthakrishnan AN, Kugathasan S, Lander ES, Blainey P, Vlamakis H, Xavier RJ, Huttenhower C. A novel Ruminococcus gnavus clade enriched in inflammatory bowel disease patients. Genome Med. 2017 Nov 28; 9(1):103. PMID: 29183332.
    Citations: 3     Fields:    Translation:HumansCells
  73. Kochar B, Barnes EL, Herfarth HH, Martin CF, Ananthakrishnan AN, McGovern D, Long M, Sandler RS. Asians have more perianal Crohn disease and ocular manifestations compared with white Americans. Inflamm Intest Dis. 2018 Mar; 2(3):147-153. PMID: 29876356.
    Citations:    
  74. Gupta A, Agarwal R, Ananthakrishnan AN. "Weekend Effect" in Patients With Upper Gastrointestinal Hemorrhage: A Systematic Review and Meta-analysis. Am J Gastroenterol. 2018 01; 113(1):13-21. PMID: 29134968.
    Citations:    Fields:    
  75. Feathers A, Swaminath A, Ananthakrishnan AN, Falzon L, Li Ferry S. Letter: enteral nutrition therapy for the induction of remission in paediatric Crohn's disease-Authors' reply. Aliment Pharmacol Ther. 2017 11; 46(10):1026-1027. PMID: 29052855.
    Citations:    Fields:    Translation:Humans
  76. Ananthakrishnan AN, Khalili H, Song M, Higuchi LM, Lochhead P, Richter JM, Chan AT. Genetic Polymorphisms in Fatty Acid Metabolism Modify the Association Between Dietary n3: n6 Intake and Risk of Ulcerative Colitis: A Prospective Cohort Study. Inflamm Bowel Dis. 2017 11; 23(11):1898-1904. PMID: 28991856.
    Citations: 2     Fields:    Translation:Humans
  77. Ananthakrishnan AN, Bernstein CN, Iliopoulos D, Macpherson A, Neurath MF, Ali RAR, Vavricka SR, Fiocchi C. Environmental triggers in IBD: a review of progress and evidence. Nat Rev Gastroenterol Hepatol. 2018 Jan; 15(1):39-49. PMID: 29018271.
    Citations: 6     Fields:    Translation:Humans
  78. Xu L, Lochhead P, Ko Y, Claggett B, Leong RW, Ananthakrishnan AN. Systematic review with meta-analysis: breastfeeding and the risk of Crohn's disease and ulcerative colitis. Aliment Pharmacol Ther. 2017 11; 46(9):780-789. PMID: 28892171.
    Citations:    Fields:    Translation:Humans
  79. Beaulieu DB, Ananthakrishnan AN, Martin C, Cohen RD, Kane SV, Mahadevan U. Use of Biologic Therapy by Pregnant Women With Inflammatory Bowel Disease Does Not Affect Infant Response to Vaccines. Clin Gastroenterol Hepatol. 2018 Jan; 16(1):99-105. PMID: 28870657.
    Citations:    Fields:    Translation:HumansCells
  80. Swaminath A, Feathers A, Ananthakrishnan AN, Falzon L, Li Ferry S. Systematic review with meta-analysis: enteral nutrition therapy for the induction of remission in paediatric Crohn's disease. Aliment Pharmacol Ther. 2017 10; 46(7):645-656. PMID: 28815649.
    Citations: 1     Fields:    Translation:Humans
  81. Kochar B, Long MD, Galanko J, Raffals LE, Ananthakrishnan A, Sandler RS. Inflammatory Bowel Disease is Similar in Patients with Older Onset and Younger Onset. Inflamm Bowel Dis. 2017 07; 23(7):1187-1194. PMID: 28410340.
    Citations: 1     Fields:    Translation:Humans
  82. Borren NZ, Conway G, Tan W, Andrews E, Garber JJ, Yajnik V, Ananthakrishnan AN. Distance to Specialist Care and Disease Outcomes in Inflammatory Bowel Disease. Inflamm Bowel Dis. 2017 07; 23(7):1234-1239. PMID: 28520589.
    Citations: 1     Fields:    Translation:Humans
  83. Khalili H, de Silva PS, Ananthakrishnan AN, Lochhead P, Joshi A, Garber JJ, Richter JR, Sauk J, Chan AT. Dietary Iron and Heme Iron Consumption, Genetic Susceptibility, and Risk of Crohn's Disease and Ulcerative Colitis. Inflamm Bowel Dis. 2017 07; 23(7):1088-1095. PMID: 28604414.
    Citations:    Fields:    Translation:Humans
  84. Shi HY, Levy AN, Trivedi HD, Chan FKL, Ng SC, Ananthakrishnan AN. Ethnicity Influences Phenotype and Outcomes in Inflammatory Bowel Disease: A Systematic Review and Meta-analysis of Population-based Studies. Clin Gastroenterol Hepatol. 2018 02; 16(2):190-197.e11. PMID: 28603049.
    Citations: 2     Fields:    
  85. Ananthakrishnan AN, Donaldson T, Lasch K, Yajnik V. Management of Inflammatory Bowel Disease in the Elderly Patient: Challenges and Opportunities. Inflamm Bowel Dis. 2017 06; 23(6):882-893. PMID: 28375885.
    Citations: 2     Fields:    Translation:Humans
  86. Ananthakrishnan AN. Issue Highlights. Clin Gastroenterol Hepatol. 2017 May 12. PMID: 28506650.
    Citations:    
  87. Ananthakrishnan AN, Luo C, Yajnik V, Khalili H, Garber JJ, Stevens BW, Cleland T, Xavier RJ. Gut Microbiome Function Predicts Response to Anti-integrin Biologic Therapy in Inflammatory Bowel Diseases. Cell Host Microbe. 2017 May 10; 21(5):603-610.e3. PMID: 28494241.
    Citations: 8     Fields:    Translation:Humans
  88. Ananthakrishnan AN, Sakuraba A, Barnes EL, Pekow J, Raffals L, Long MD, Sandler RS. The benefit of combination therapy depends on disease phenotype and duration in Crohn's disease. Aliment Pharmacol Ther. 2017 07; 46(2):162-168. PMID: 28470787.
    Citations:    Fields:    Translation:Humans
  89. Borren NZ, Ghadermarzi S, Hutfless S, Ananthakrishnan AN. The emergence of Clostridium difficile infection in Asia: A systematic review and meta-analysis of incidence and impact. PLoS One. 2017; 12(5):e0176797. PMID: 28463987.
    Citations: 5     Fields:    Translation:HumansCells
  90. Burke KE, Boumitri C, Ananthakrishnan AN. Modifiable Environmental Factors in Inflammatory Bowel Disease. Curr Gastroenterol Rep. 2017 May; 19(5):21. PMID: 28397132.
    Citations: 3     Fields:    Translation:Humans
  91. Yu S, Chakrabortty A, Liao KP, Cai T, Ananthakrishnan AN, Gainer VS, Churchill SE, Szolovits P, Murphy SN, Kohane IS, Cai T. Surrogate-assisted feature extraction for high-throughput phenotyping. J Am Med Inform Assoc. 2017 Apr 01; 24(e1):e143-e149. PMID: 27632993.
    Citations: 1     Fields:    Translation:Humans
  92. Ananthakrishnan AN. Editorial: co-existing immune-mediated disease in inflammatory bowel diseases - a new disease severity indicator? Author's reply. Aliment Pharmacol Ther. 2017 04; 45(8):1168. PMID: 28326587.
    Citations:    Fields:    Translation:Humans
  93. Allegretti JR, Barnes EL, Stevens B, Storm M, Ananthakrishnan A, Yajnik V, Korzenik J. Predictors of Clinical Response and Remission at 1 Year Among a Multicenter Cohort of Patients with Inflammatory Bowel Disease Treated with Vedolizumab. Dig Dis Sci. 2017 06; 62(6):1590-1596. PMID: 28357697.
    Citations: 2     Fields:    Translation:Humans
  94. Cholapranee A, Hazlewood GS, Kaplan GG, Peyrin-Biroulet L, Ananthakrishnan AN. Systematic review with meta-analysis: comparative efficacy of biologics for induction and maintenance of mucosal healing in Crohn's disease and ulcerative colitis controlled trials. Aliment Pharmacol Ther. 2017 May; 45(10):1291-1302. PMID: 28326566.
    Citations: 14     Fields:    Translation:Humans
  95. Bopanna S, Ananthakrishnan AN, Kedia S, Yajnik V, Ahuja V. Risk of colorectal cancer in Asian patients with ulcerative colitis: a systematic review and meta-analysis. Lancet Gastroenterol Hepatol. 2017 04; 2(4):269-276. PMID: 28404156.
    Citations: 4     Fields:    Translation:Humans
  96. Sasidharan S, Yajnik V, Khalili H, Garber J, Xavier R, Ananthakrishnan AN. Genetic risk factors for serious infections in inflammatory bowel diseases. Scand J Gastroenterol. 2017 May; 52(5):570-576. PMID: 28162010.
    Citations: 1     Fields:    Translation:Humans
  97. Borren N, Goel G, Lassen K, Devaney K, Cleland T, Garber J, Khalili H, Yajnik V, Xavier R, Ananthakrishnan A. P023 Fatigue in quiescent inflammatory bowel disease is associated with low GM-CSF levels and metabolomic alterations. J Crohns Colitis. 2017 Feb 01; 11(suppl_1):S91-S92. PMID: 28174948.
    Citations:    
  98. Chen Y, Furuya-Kanamori L, Doi SA, Ananthakrishnan AN, Kirk M. Clostridium difficile Infection and Risk of Colectomy in Patients with Inflammatory Bowel Disease: A Bias-adjusted Meta-analysis. Inflamm Bowel Dis. 2017 02; 23(2):200-207. PMID: 28079620.
    Citations: 2     Fields:    Translation:HumansCells
  99. Velonias G, Conway G, Andrews E, Garber JJ, Khalili H, Yajnik V, Ananthakrishnan AN. Older Age- and Health-related Quality of Life in Inflammatory Bowel Diseases. Inflamm Bowel Dis. 2017 02; 23(2):283-288. PMID: 28079625.
    Citations:    Fields:    Translation:Humans
  100. Borren N, Conway G, Garber J, Khalili H, Yajnik V, Xavier R, Ananthakrishnan A. P688 Crohn's disease patients with a concordant family history are diagnosed earlier and are at increased risk for complicated disease. J Crohns Colitis. 2017 Feb 01; 11(suppl_1):S431-S432. PMID: 28172996.
    Citations:    
  101. Borren N, Tan W, Andrews E, Khalili H, Garber J, Yajnik V, Ananthakrishnan A. P704 The impact of travel distance on disease outcomes in inflammatory bowel disease. J Crohns Colitis. 2017 Feb 01; 11(suppl_1):S441. PMID: 28175236.
    Citations:    
  102. Stevens BW, Borren NZ, Velonias G, Conway G, Cleland T, Andrews E, Khalili H, Garber JJ, Xavier RJ, Yajnik V, Ananthakrishnan AN. Erratum to: Vedolizumab Therapy Is Associated with an Improvement in Sleep Quality and Mood in Inflammatory Bowel Diseases. Dig Dis Sci. 2017 02; 62(2):552. PMID: 27864657.
    Citations:    Fields:    
  103. Singh P, Ananthakrishnan A, Ahuja V. Pivot to Asia: inflammatory bowel disease burden. Intest Res. 2017 Jan; 15(1):138-141. PMID: 28239326.
    Citations: 12     
  104. Conway G, Velonias G, Andrews E, Garber JJ, Yajnik V, Ananthakrishnan AN. The impact of co-existing immune-mediated diseases on phenotype and outcomes in inflammatory bowel diseases. Aliment Pharmacol Ther. 2017 Mar; 45(6):814-823. PMID: 28105709.
    Citations: 3     Fields:    
  105. Van Der Sloot KW, Joshi AD, Bellavance DR, Gilpin KK, Stewart KO, Lochhead P, Garber JJ, Giallourakis C, Yajnik V, Ananthakrishnan AN, Alizadeh BZ, Xavier RJ, Khalili H. Visceral Adiposity, Genetic Susceptibility, and Risk of Complications Among Individuals with Crohn's Disease. Inflamm Bowel Dis. 2017 01; 23(1):82-88. PMID: 27893544.
    Citations: 5     Fields:    Translation:Humans
  106. Ananthakrishnan AN. Filgotinib for Crohn's disease-expanding treatment options. Lancet. 2017 01 21; 389(10066):228-229. PMID: 27988141.
    Citations: 2     Fields:    Translation:Humans
  107. Khalili H, Malik S, Ananthakrishnan AN, Garber JJ, Higuchi LM, Joshi A, Peloquin J, Richter JM, Stewart KO, Curhan GC, Awasthi A, Yajnik V, Chan AT. Identification and Characterization of a Novel Association between Dietary Potassium and Risk of Crohn's Disease and Ulcerative Colitis. Front Immunol. 2016; 7:554. PMID: 28003811.
    Citations: 3     
  108. Shelton E, Ananthakrishnan AN. Reply. Gastroenterology. 2017 01; 152(1):306. PMID: 27893976.
    Citations:    Fields:    
  109. Mao EJ, Hazlewood GS, Kaplan GG, Peyrin-Biroulet L, Ananthakrishnan AN. Systematic review with meta-analysis: comparative efficacy of immunosuppressants and biologics for reducing hospitalisation and surgery in Crohn's disease and ulcerative colitis. Aliment Pharmacol Ther. 2017 01; 45(1):3-13. PMID: 27862107.
    Citations: 7     Fields:    Translation:Humans
  110. Rodrigues R, Barber GE, Ananthakrishnan AN. A Comprehensive Study of Costs Associated With Recurrent Clostridium difficile Infection. Infect Control Hosp Epidemiol. 2017 02; 38(2):196-202. PMID: 27817758.
    Citations: 5     Fields:    Translation:HumansCells
  111. Pratap Mouli V, Munot K, Ananthakrishnan A, Kedia S, Addagalla S, Garg SK, Benjamin J, Singla V, Dhingra R, Tiwari V, Bopanna S, Hutfless S, Makharia G, Ahuja V. Endoscopic and clinical responses to anti-tubercular therapy can differentiate intestinal tuberculosis from Crohn's disease. Aliment Pharmacol Ther. 2017 01; 45(1):27-36. PMID: 27813111.
    Citations: 6     Fields:    Translation:Humans
  112. Stevens BW, Borren NZ, Velonias G, Conway G, Cleland T, Andrews E, Khalili H, Garber JG, Xavier RJ, Yajnik V, Ananthakrishnan AN. Vedolizumab Therapy Is Associated with an Improvement in Sleep Quality and Mood in Inflammatory Bowel Diseases. Dig Dis Sci. 2017 01; 62(1):197-206. PMID: 27796768.
    Citations:    Fields:    Translation:Humans
  113. Rivas MA, Graham D, Sulem P, Stevens C, Desch AN, Goyette P, Gudbjartsson D, Jonsdottir I, Thorsteinsdottir U, Degenhardt F, Mucha S, Kurki MI, Li D, D'Amato M, Annese V, Vermeire S, Weersma RK, Halfvarson J, Paavola-Sakki P, Lappalainen M, Lek M, Cummings B, Tukiainen T, Haritunians T, Halme L, Koskinen LL, Ananthakrishnan AN, Luo Y, Heap GA, Visschedijk MC, MacArthur DG, Neale BM, Ahmad T, Anderson CA, Brant SR, Duerr RH, Silverberg MS, Cho JH, Palotie A, Saavalainen P, Kontula K, Färkkilä M, McGovern DP, Franke A, Stefansson K, Rioux JD, Xavier RJ, Daly MJ. Erratum: A protein-truncating R179X variant in RNF186 confers protection against ulcerative colitis. Nat Commun. 2016 09 13; 7:12869. PMID: 27619887.
    Citations:    Fields:    
  114. Barber GE, Yajnik V, Khalili H, Giallourakis C, Garber J, Xavier R, Ananthakrishnan AN. Genetic Markers Predict Primary Non-Response and Durable Response To Anti-TNF Biologic Therapies in Crohn's Disease. Am J Gastroenterol. 2016 12; 111(12):1816-1822. PMID: 27596696.
    Citations: 5     Fields:    Translation:Humans
  115. Cholapranee A, Ananthakrishnan AN. Environmental Hygiene and Risk of Inflammatory Bowel Diseases: A Systematic Review and Meta-analysis. Inflamm Bowel Dis. 2016 09; 22(9):2191-9. PMID: 27482977.
    Citations: 3     Fields:    Translation:HumansAnimalsPHPublic Health
  116. Law CC, Sasidharan S, Rodrigues R, Nguyen DD, Sauk J, Garber J, Giallourakis C, Xavier R, Khalili H, Yajnik V, Ananthakrishnan AN. Impact of Specialized Inpatient IBD Care on Outcomes of IBD Hospitalizations: A Cohort Study. Inflamm Bowel Dis. 2016 09; 22(9):2149-57. PMID: 27482978.
    Citations: 2     Fields:    Translation:Humans
  117. Rivas MA, Graham D, Sulem P, Stevens C, Desch AN, Goyette P, Gudbjartsson D, Jonsdottir I, Thorsteinsdottir U, Degenhardt F, Mucha S, Kurki MI, Li D, D'Amato M, Annese V, Vermeire S, Weersma RK, Halfvarson J, Paavola-Sakki P, Lappalainen M, Lek M, Cummings B, Tukiainen T, Haritunians T, Halme L, Koskinen LL, Ananthakrishnan AN, Luo Y, Heap GA, Visschedijk MC, MacArthur DG, Neale BM, Ahmad T, Anderson CA, Brant SR, Duerr RH, Silverberg MS, Cho JH, Palotie A, Saavalainen P, Kontula K, Färkkilä M, McGovern DP, Franke A, Stefansson K, Rioux JD, Xavier RJ, Daly MJ, Barrett J, de Lane K, Edwards C, Hart A, Hawkey C, Jostins L, Kennedy N, Lamb C, Lee J, Lees C, Mansfield J, Mathew C, Mowatt C, Newman B, Nimmo E, Parkes M, Pollard M, Prescott N, Randall J, Rice D, Satsangi J, Simmons A, Tremelling M, Uhlig H, Wilson D, Abraham C, Achkar JP, Bitton A, Boucher G, Croitoru K, Fleshner P, Glas J, Kugathasan S, Limbergen JV, Milgrom R, Proctor D, Regueiro M, Schumm PL, Sharma Y, Stempak JM, Targan SR, Wang MH. A protein-truncating R179X variant in RNF186 confers protection against ulcerative colitis. Nat Commun. 2016 08 09; 7:12342. PMID: 27503255.
    Citations: 5     Fields:    Translation:Humans
  118. Rajbhandari R, Simon RE, Chung RT, Ananthakrishnan AN. Racial Disparities in Inhospital Outcomes for Hepatocellular Carcinoma in the United States. Mayo Clin Proc. 2016 Sep; 91(9):1173-82. PMID: 27497857.
    Citations: 2     Fields:    Translation:Humans
  119. Li D, Achkar JP, Haritunians T, Jacobs JP, Hui KY, D'Amato M, Brand S, Radford-Smith G, Halfvarson J, Niess JH, Kugathasan S, Büning C, Schumm LP, Klei L, Ananthakrishnan A, Aumais G, Baidoo L, Dubinsky M, Fiocchi C, Glas J, Milgrom R, Proctor DD, Regueiro M, Simms LA, Stempak JM, Targan SR, Törkvist L, Sharma Y, Devlin B, Borneman J, Hakonarson H, Xavier RJ, Daly M, Brant SR, Rioux JD, Silverberg MS, Cho JH, Braun J, McGovern DP, Duerr RH. A Pleiotropic Missense Variant in SLC39A8 Is Associated With Crohn's Disease and Human Gut Microbiome Composition. Gastroenterology. 2016 10; 151(4):724-32. PMID: 27492617.
    Citations: 14     Fields:    Translation:Humans
  120. Ananthakrishnan AN. Vitamin D and Inflammatory Bowel Disease. Gastroenterol Hepatol (N Y). 2016 Aug; 12(8):513-515.