Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Jennifer Rose Gatchel, M.D.


The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. K23AG058805 (GATCHEL, JENNIFER ROSE) Apr 1, 2018 - Mar 31, 2023
    Depressive symptoms in the pathogenesis of preclinical Alzheimer's Disease
    Role: Principal Investigator
  2. F30MH072117 (GATCHEL, JENNIFER R) Sep 27, 2004 - Sep 26, 2008
    Studying the Mechanism of Neuronal Dysfunction in SCA7
    Role: Principal Investigator

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Eikelboom WS, Pan M, Ossenkoppele R, Coesmans M, Gatchel JR, Ismail Z, Lanctôt KL, Fischer CE, Mortby ME, van den Berg E, Papma JM. Sex differences in neuropsychiatric symptoms in Alzheimer's disease dementia: a meta-analysis. Alzheimers Res Ther. 2022 04 04; 14(1):48. PMID: 35379344; PMCID: PMC8978393.
    Citations:    Fields:    Translation:Humans
  2. Willey B, Mimmack K, Gagliardi G, Dossett ML, Wang S, Udeogu OJ, Donovan NJ, Gatchel JR, Quiroz YT, Amariglio R, Liu CH, Hyun S, ElTohamy A, Rentz D, Sperling RA, Marshall GA, Vannini P. Racial and socioeconomic status differences in stress, posttraumatic growth, and mental health in an older adult cohort during the COVID-19 pandemic. EClinicalMedicine. 2022 Mar; 45:101343. PMID: 35291556; PMCID: PMC8917957.
  3. Munro CE, Buckley R, Vannini P, DeMuro C, Sperling R, Rentz DM, Johnson K, Gatchel JR, Amariglio R. Longitudinal Trajectories of Participant- and Study Partner-Rated Cognitive Decline, in Relation to Alzheimer's Disease Biomarkers and Mood Symptoms. Front Aging Neurosci. 2021; 13:806432. PMID: 35173601; PMCID: PMC8841868.
  4. Montejo L, Torrent C, Jiménez E, Martínez-Arán A, Blumberg HP, Burdick KE, Chen P, Dols A, Eyler LT, Forester BP, Gatchel JR, Gildengers A, Kessing LV, Miskowiak KW, Olagunju AT, Patrick RE, Schouws S, Radua J, Bonnín CDM, Vieta E. Cognition in older adults with bipolar disorder: An ISBD task force systematic review and meta-analysis based on a comprehensive neuropsychological assessment. Bipolar Disord. 2022 03; 24(2):115-136. PMID: 34978124.
    Citations: 1     Fields:    Translation:Humans
  5. Agüera-Ortiz L, Babulal GM, Bruneau MA, Creese B, D'Antonio F, Fischer CE, Gatchel JR, Ismail Z, Kumar S, McGeown WJ, Mortby ME, Nuñez NA, de Oliveira FF, Pereiro AX, Ravona-Springer R, Rouse HJ, Wang H, Lanctôt KL. Psychosis as a Treatment Target in Dementia: A Roadmap for Designing Interventions. J Alzheimers Dis. 2022; 88(4):1203-1228. PMID: 35786651; PMCID: PMC9484097.
    Citations:    Fields:    
  6. Vannini P, Gagliardi GP, Kuppe M, Dossett ML, Donovan NJ, Gatchel JR, Quiroz YT, Premnath PY, Amariglio R, Sperling RA, Marshall GA. Corrigendum to "Stress, resilience, and coping strategies in a sample of community-dwelling older adults during COVID-19" [J. Psychiatr. Res. 138 (2021) 176-185]. J Psychiatr Res. 2021 Oct; 142:167-170. PMID: 34359011.
    Citations:    Fields:    
  7. Martinez JE, Pardilla-Delgado E, Guzmán-Vélez E, Vila-Castelar C, Amariglio R, Gatchel J, Aguirre-Acevedo DC, Bocanegra Y, Baena A, Henao E, Tirado V, Muñoz C, Giraldo-Chica M, Lopera F, Quiroz YT. Subjective Cognitive Decline and its Relation to Verbal Memory and Sex in Cognitively Unimpaired Individuals from a Colombian Cohort with Autosomal-Dominant Alzheimer's Disease. J Int Neuropsychol Soc. 2022 07; 28(6):541-549. PMID: 34187609; PMCID: PMC8716677.
    Citations: 1     Fields:    Translation:Humans
  8. Babulal GM, Torres VL, Acosta D, Agüero C, Aguilar-Navarro S, Amariglio R, Ussui JA, Baena A, Bocanegra Y, Brucki SMD, Bustin J, Cabrera DM, Custodio N, Diaz MM, Peñailillo LD, Franco I, Gatchel JR, Garza-Naveda AP, González Lara M, Gutiérrez-Gutiérrez L, Guzmán-Vélez E, Hanseeuw BJ, Jimenez-Velazquez IZ, Rodríguez TL, Llibre-Guerra J, Marquine MJ, Martinez J, Medina LD, Miranda-Castillo C, Morlett Paredes A, Munera D, Nuñez-Herrera A, de Oliveira MO, Palmer-Cancel SJ, Pardilla-Delgado E, Perales-Puchalt J, Pluim C, Ramirez-Gomez L, Rentz DM, Rivera-Fernández C, Rosselli M, Serrano CM, Suing-Ortega MJ, Slachevsky A, Soto-Añari M, Sperling RA, Torrente F, Thumala D, Vannini P, Vila-Castelar C, Yañez-Escalante T, Quiroz YT. The impact of COVID-19 on the well-being and cognition of older adults living in the United States and Latin America. EClinicalMedicine. 2021 May; 35:100848. PMID: 33997742; PMCID: PMC8100067.
    Citations: 5     
  9. Vannini P, Gagliardi GP, Kuppe M, Dossett ML, Donovan NJ, Gatchel JR, Quiroz YT, Premnath PY, Amariglio R, Sperling RA, Marshall GA. Stress, resilience, and coping strategies in a sample of community-dwelling older adults during COVID-19. J Psychiatr Res. 2021 06; 138:176-185. PMID: 33862301; PMCID: PMC8369528.
    Citations: 9     Fields:    Translation:HumansCellsPHPublic Health
  10. Tommasi NS, Gonzalez C, Briggs D, Properzi MJ, Gatchel JR, Marshall GA. Affective symptoms and regional cerebral tau burden in early-stage Alzheimer's disease. Int J Geriatr Psychiatry. 2021 07; 36(7):1050-1058. PMID: 33682933; PMCID: PMC8187284.
    Citations:    Fields:    Translation:Humans
  11. Guzmán-Vélez E, Zetterberg H, Fox-Fuller JT, Vila-Castelar C, Sanchez JS, Baena A, Garcia-Ospina G, Aguillon D, Pardilla-Delgado E, Gatchel JR, Sperling RA, Johnson K, Reiman EM, Blennow K, Lopera F, Quiroz YT. Associations between plasma neurofilament light, in vivo brain pathology, and cognition in non-demented individuals with autosomal-dominant Alzheimer's disease. Alzheimers Dement. 2021 05; 17(5):813-821. PMID: 33527648; PMCID: PMC8158654.
    Citations: 4     Fields:    Translation:Humans
  12. Sanchez JS, Hanseeuw BJ, Lopera F, Sperling RA, Baena A, Bocanegra Y, Aguillon D, Guzmán-Vélez E, Pardilla-Delgado E, Ramirez-Gomez L, Vila-Castelar C, Martinez JE, Fox-Fuller JT, Ramos C, Ochoa-Escudero M, Alvarez S, Jacobs HIL, Schultz AP, Gatchel JR, Becker JA, Katz SR, Mayblyum DV, Price JC, Reiman EM, Johnson KA, Quiroz YT. Longitudinal amyloid and tau accumulation in autosomal dominant Alzheimer's disease: findings from the Colombia-Boston (COLBOS) biomarker study. Alzheimers Res Ther. 2021 01 15; 13(1):27. PMID: 33451357.
    Citations: 11     Fields:    Translation:Humans
  13. Baena A, Bocanegra Y, Torres V, Vila-Castelar C, Guzmán-Vélez E, Fox-Fuller JT, Gatchel JR, Sánchez J, Pluim CF, Ramirez-Gómez L, Martínez J, Pineda D, Lopera F, Quiroz YT. Neuroticism Is Associated with Tau Pathology in Cognitively Unimpaired Individuals with Autosomal Dominant Alzheimer's Disease. J Alzheimers Dis. 2021; 82(4):1809-1822. PMID: 34219716; PMCID: PMC9113533.
    Citations: 1     Fields:    Translation:Humans
  14. Olagunju AT, Morgan JA, Aftab A, Gatchel JR, Chen P, Dols A, Sajatovic M, Regenold WT. A Review of the Evidence Base for Nutrition and Nutritional Supplements in Older Adults with Bipolar Disorder: A report from the OABD task force. J Frailty Aging. 2021; 10(3):241-246. PMID: 34105708; PMCID: PMC8715337.
    Citations: 2     Fields:    Translation:Humans
  15. Amariglio RE, Sikkes SAM, Marshall GA, Buckley RF, Gatchel JR, Johnson KA, Rentz DM, Donohue MC, Raman R, Sun CK, Yaari R, Holdridge KC, Sims JR, Grill JD, Aisen PS, Sperling RA. Item-Level Investigation of Participant and Study Partner Report on the Cognitive Function Index from the A4 Study Screening Data. J Prev Alzheimers Dis. 2021; 8(3):257-262. PMID: 34101781; PMCID: PMC8240963.
    Citations: 3     Fields:    Translation:Humans
  16. Vannini P, Hanseeuw BJ, Gatchel JR, Sikkes SAM, Alzate D, Zuluaga Y, Moreno S, Mendez L, Baena A, Ospina-Lopera P, Tirado V, Henao E, Acosta-Baena N, Giraldo M, Lopera F, Quiroz YT. Trajectory of Unawareness of Memory Decline in Individuals With Autosomal Dominant Alzheimer Disease. JAMA Netw Open. 2020 12 01; 3(12):e2027472. PMID: 33263761.
    Citations: 6     Fields:    Translation:Humans
  17. Gatchel JR. Late-Life Depression and Alzheimer's Disease Pathology: An Ounce of Prevention, a Pound of Cure. Am J Geriatr Psychiatry. 2021 05; 29(5):458-461. PMID: 33293249.
    Citations:    Fields:    Translation:Humans
  18. Marshall GA, Sikkes SAM, Amariglio RE, Gatchel JR, Rentz DM, Johnson KA, Langford O, Sun CK, Donohue MC, Raman R, Aisen PS, Sperling RA, Galasko DR. Instrumental activities of daily living, amyloid, and cognition in cognitively normal older adults screening for the A4 Study. Alzheimers Dement (Amst). 2020; 12(1):e12118. PMID: 33163609; PMCID: PMC7596668.
    Citations: 2     
  19. Blanken MAJT, Oudega ML, Schouws SNTM, van Zanten JS, Gatchel JR, Regenold WT, Dols A. Is ECT a viable option to treat depression in older adults with bipolar disorder who are vulnerable to cognitive side effects? Bipolar Disord. 2021 Mar; 23(2):218-220. PMID: 32985049; PMCID: PMC7984253.
    Citations:    Fields:    Translation:Humans
  20. Rabin JS, Shirzadi Z, Swardfager W, MacIntosh BJ, Schultz A, Yang HS, Buckley RF, Gatchel JR, Kirn D, Pruzin JJ, Hedden T, Lipsman N, Rentz DM, Black SE, Johnson KA, Sperling RA, Chhatwal JP. Amyloid-beta burden predicts prospective decline in body mass index in clinically normal adults. Neurobiol Aging. 2020 09; 93:124-130. PMID: 32249013.
    Citations: 6     Fields:    Translation:Humans
  21. Gatchel JR, Lopera F, Norton DJ, Baena A, Guzman-Velez E, Sanchez JS, d'Oleire Uquillas F, Schultz A, Vannini P, Artola A, Amariglio RE, Rentz DM, Tariot PN, Reiman EM, Johnson KA, Sperling RA, Marshall GA, Quiroz YT. Association of subjective cognitive decline with markers of brain pathology in preclinical autosomal dominant Alzheimer's disease. J Neurol Neurosurg Psychiatry. 2020 03; 91(3):330-332. PMID: 31874859; PMCID: PMC7397724.
    Citations: 5     Fields:    Translation:Humans
  22. Hanseeuw BJ, Scott MR, Sikkes SAM, Properzi M, Gatchel JR, Salmon E, Marshall GA, Vannini P. Evolution of anosognosia in alzheimer's disease and its relationship to amyloid. Ann Neurol. 2020 02; 87(2):267-280. PMID: 31750553; PMCID: PMC6980336.
    Citations: 18     Fields:    Translation:Humans
  23. Vannini P, d'Oleire Uquillas F, Jacobs HIL, Sepulcre J, Gatchel J, Amariglio RE, Hanseeuw B, Papp KV, Hedden T, Rentz DM, Pascual-Leone A, Johnson KA, Sperling RA. Decreased meta-memory is associated with early tauopathy in cognitively unimpaired older adults. Neuroimage Clin. 2019; 24:102097. PMID: 31795044.
    Citations: 3     Fields:    Translation:Humans
  24. Gatchel JR. Late-Life Neuropsychiatric Symptoms: Windows Into Cognitive Decline? Am J Geriatr Psychiatry. 2020 01; 28(1):72-74. PMID: 31526547.
    Citations: 1     Fields:    Translation:Humans
  25. Gatchel JR, Rabin JS, Buckley RF, Locascio JJ, Quiroz YT, Yang HS, Vannini P, Amariglio RE, Rentz DM, Properzi M, Donovan NJ, Blacker D, Johnson KA, Sperling RA, Marshall GA. Longitudinal Association of Depression Symptoms With Cognition and Cortical Amyloid Among Community-Dwelling Older Adults. JAMA Netw Open. 2019 08 02; 2(8):e198964. PMID: 31397865.
    Citations: 24     Fields:    Translation:Humans
  26. Capuano AW, Wilson RS, Honer WG, Petyuk VA, Leurgans SE, Yu L, Gatchel JR, Arnold S, Bennett DA, Arvanitakis Z. Brain IGFBP-5 modifies the relation of depressive symptoms to decline in cognition in older persons. J Affect Disord. 2019 05 01; 250:313-318. PMID: 30875674.
    Citations: 4     Fields:    Translation:Humans
  27. Hanseeuw BJ, Lopera F, Sperling RA, Norton DJ, Guzman-Velez E, Baena A, Pardilla-Delgado E, Schultz AP, Gatchel J, Jin D, Chen K, Reiman EM, Johnson KA, Quiroz YT. Striatal amyloid is associated with tauopathy and memory decline in familial Alzheimer's disease. Alzheimers Res Ther. 2019 02 04; 11(1):17. PMID: 30717814; PMCID: PMC6362587.
    Citations: 10     Fields:    Translation:Humans
  28. Halawa OA, Gatchel JR, Amariglio RE, Rentz DM, Sperling RA, Johnson KA, Marshall GA. Inferior and medial temporal tau and cortical amyloid are associated with daily functional impairment in Alzheimer's disease. Alzheimers Res Ther. 2019 01 31; 11(1):14. PMID: 30704519; PMCID: PMC6357436.
    Citations: 9     Fields:    Translation:Humans
  29. Sperling RA, Mormino EC, Schultz AP, Betensky RA, Papp KV, Amariglio RE, Hanseeuw BJ, Buckley R, Chhatwal J, Hedden T, Marshall GA, Quiroz YT, Donovan NJ, Jackson J, Gatchel JR, Rabin JS, Jacobs H, Yang HS, Properzi M, Kirn DR, Rentz DM, Johnson KA. The impact of amyloid-beta and tau on prospective cognitive decline in older individuals. Ann Neurol. 2019 02; 85(2):181-193. PMID: 30549303.
    Citations: 68     Fields:    Translation:Humans
  30. Rabin JS, Yang HS, Schultz AP, Hanseeuw BJ, Hedden T, Viswanathan A, Gatchel JR, Marshall GA, Kilpatrick E, Klein H, Rao V, Buckley RF, Yau WW, Kirn DR, Rentz DM, Johnson KA, Sperling RA, Chhatwal JP. Vascular Risk and ß-Amyloid Are Synergistically Associated with Cortical Tau. Ann Neurol. 2019 02; 85(2):272-279. PMID: 30565287.
    Citations: 33     Fields:    Translation:Humans
  31. Yang HS, Chhatwal JP, Xu J, White CC, Hanseeuw B, Rabin JS, Papp KV, Buckley RF, Schultz AP, Properzi MJ, Gatchel JR, Amariglio RE, Donovan NJ, Mormino EC, Hedden T, Marshall GA, Rentz DM, Johnson KA, De Jager PL, Sperling RA. An UNC5C Allele Predicts Cognitive Decline and Hippocampal Atrophy in Clinically Normal Older Adults. J Alzheimers Dis. 2019; 68(3):1161-1170. PMID: 30883345; PMCID: PMC6571137.
    Citations: 1     Fields:    Translation:Humans
  32. Fuller JT, Cronin-Golomb A, Gatchel JR, Norton DJ, Guzmán-Vélez E, Jacobs HIL, Hanseeuw B, Pardilla-Delgado E, Artola A, Baena A, Bocanegra Y, Kosik KS, Chen K, Tariot PN, Johnson K, Sperling RA, Reiman EM, Lopera F, Quiroz YT. Biological and Cognitive Markers of Presenilin1 E280A Autosomal Dominant Alzheimer's Disease: A Comprehensive Review of the Colombian Kindred. J Prev Alzheimers Dis. 2019; 6(2):112-120. PMID: 30756118.
    Citations: 19     Fields:    Translation:Humans
  33. Marshall GA, Gatchel JR, Donovan NJ, Muniz MC, Schultz AP, Becker JA, Chhatwal JP, Hanseeuw BJ, Papp KV, Amariglio RE, Rentz DM, Sperling RA, Johnson KA. Regional Tau Correlates of Instrumental Activities of Daily Living and Apathy in Mild Cognitive Impairment and Alzheimer's Disease Dementia. J Alzheimers Dis. 2019; 67(2):757-768. PMID: 30689584; PMCID: PMC6352915.
    Citations: 11     Fields:    Translation:Humans
  34. Ismail Z, Gatchel J, Bateman DR, Barcelos-Ferreira R, Cantillon M, Jaeger J, Donovan NJ, Mortby ME. Affective and emotional dysregulation as pre-dementia risk markers: exploring the mild behavioral impairment symptoms of depression, anxiety, irritability, and euphoria - CORRIGENDUM. Int Psychogeriatr. 2019 01; 31(1):157. PMID: 30461372; PMCID: PMC7864664.
    Citations: 4     Fields:    
  35. Donovan NJ, Locascio JJ, Marshall GA, Gatchel J, Hanseeuw BJ, Rentz DM, Johnson KA, Sperling RA. Longitudinal Association of Amyloid Beta and Anxious-Depressive Symptoms in Cognitively Normal Older Adults. Am J Psychiatry. 2018 06 01; 175(6):530-537. PMID: 29325447; PMCID: PMC5988933.
    Citations: 66     Fields:    Translation:Humans
  36. Ehrenberg AJ, Suemoto CK, França Resende EP, Petersen C, Leite REP, Rodriguez RD, Ferretti-Rebustini REL, You M, Oh J, Nitrini R, Pasqualucci CA, Jacob-Filho W, Kramer JH, Gatchel JR, Grinberg LT. Neuropathologic Correlates of Psychiatric Symptoms in Alzheimer's Disease. J Alzheimers Dis. 2018; 66(1):115-126. PMID: 30223398; PMCID: PMC6381997.
    Citations: 44     Fields:    Translation:Humans
  37. Rej S, Quayle W, Forester BP, Dols A, Gatchel J, Chen P, Gough S, Fox R, Sajatovic M, Strejilevich SA, Eyler LT. Measurement tools for assessment of older age bipolar disorder: A systematic review of the recent global literature. Bipolar Disord. 2018 06; 20(4):359-369. PMID: 29108106.
    Citations: 1     Fields:    Translation:Humans
  38. Ismail Z, Gatchel J, Bateman DR, Barcelos-Ferreira R, Cantillon M, Jaeger J, Donovan NJ, Mortby ME. Affective and emotional dysregulation as pre-dementia risk markers: exploring the mild behavioral impairment symptoms of depression, anxiety, irritability, and euphoria. Int Psychogeriatr. 2018 02; 30(2):185-196. PMID: 28899446.
    Citations: 48     Fields:    Translation:Humans
  39. Wang S, Wu Y, Ungvari GS, Ng CH, Forester BP, Gatchel JR, Chiu HFK, Kou C, Fu Y, Qi Y, Yu Y, Li B, Xiang YT. Sleep duration and its association with demographics, lifestyle factors, poor mental health and chronic diseases in older Chinese adults. Psychiatry Res. 2017 11; 257:212-218. PMID: 28777953.
    Citations: 13     Fields:    Translation:Humans
  40. Gatchel JR, Forester BP. Editorial Comment: Running Out of Time: Clock Copying as a Psychometric to Predict Mortality in Vulnerable Older Adults? Am J Geriatr Psychiatry. 2017 09; 25(9):1017-1018. PMID: 28600125.
    Citations:    Fields:    Translation:Humans
  41. Mormino EC, Papp KV, Rentz DM, Donohue MC, Amariglio R, Quiroz YT, Chhatwal J, Marshall GA, Donovan N, Jackson J, Gatchel JR, Hanseeuw BJ, Schultz AP, Aisen PS, Johnson KA, Sperling RA. Early and late change on the preclinical Alzheimer's cognitive composite in clinically normal older individuals with elevated amyloid ß. Alzheimers Dement. 2017 Sep; 13(9):1004-1012. PMID: 28253478; PMCID: PMC5573651.
    Citations: 74     Fields:    Translation:Humans
  42. Gatchel JR, Donovan NJ, Locascio JJ, Becker JA, Rentz DM, Sperling RA, Johnson KA, Marshall GA. Regional 18F-Fluorodeoxyglucose Hypometabolism is Associated with Higher Apathy Scores Over Time in Early Alzheimer Disease. Am J Geriatr Psychiatry. 2017 Jul; 25(7):683-693. PMID: 28410856.
    Citations: 12     Fields:    Translation:Humans
  43. Gatchel JR. Positive Psychiatry: A Clinical Handbook, Edited by Dilip V. Jeste and Barton W. Palmer. Psychiatry. 2017; 80(2):203-205. PMID: 28767334.
  44. Gatchel JR, Donovan NJ, Locascio JJ, Schultz AP, Becker JA, Chhatwal J, Papp KV, Amariglio RE, Rentz DM, Blacker D, Sperling RA, Johnson KA, Marshall GA. Depressive Symptoms and Tau Accumulation in the Inferior Temporal Lobe and Entorhinal Cortex in Cognitively Normal Older Adults: A Pilot Study. J Alzheimers Dis. 2017; 59(3):975-985. PMID: 28697559; PMCID: PMC5577564.
    Citations: 31     Fields:    Translation:Humans
  45. Lokko HN, Gatchel JR, Becker MA, Stern TA. The Art and Science of Learning, Teaching, and Delivering Feedback in Psychosomatic Medicine. Psychosomatics. 2016 Jan-Feb; 57(1):31-40. PMID: 26683348.
    Citations:    Fields:    Translation:Humans
  46. Gatchel J, Legesse B, Tayeb S, Murray E, Price B. Neurosyphilis in psychiatric practice: a case-based discussion of clinical evaluation and diagnosis. Gen Hosp Psychiatry. 2015 Sep-Oct; 37(5):459-63. PMID: 26022384.
    Citations: 1     Fields:    Translation:Humans
  47. Forester BP, Gatchel JR. Medical co-morbidity, brain disease, and the future of geriatric psychiatry. Am J Geriatr Psychiatry. 2014 Nov; 22(11):1061-5. PMID: 25307312.
    Citations:    Fields:    Translation:Humans
  48. Perroud B, Jafar-Nejad P, Wikoff WR, Gatchel JR, Wang L, Barupal DK, Crespo-Barreto J, Fiehn O, Zoghbi HY, Kaddurah-Daouk R. Pharmacometabolomic signature of ataxia SCA1 mouse model and lithium effects. PLoS One. 2013; 8(8):e70610. PMID: 23936457.
    Citations: 5     Fields:    Translation:Animals
  49. Chen YC, Gatchel JR, Lewis RW, Mao CA, Grant PA, Zoghbi HY, Dent SY. Gcn5 loss-of-function accelerates cerebellar and retinal degeneration in a SCA7 mouse model. Hum Mol Genet. 2012 Jan 15; 21(2):394-405. PMID: 22002997.
    Citations: 32     Fields:    Translation:AnimalsCells
  50. Lee Y, Samaco RC, Gatchel JR, Thaller C, Orr HT, Zoghbi HY. miR-19, miR-101 and miR-130 co-regulate ATXN1 levels to potentially modulate SCA1 pathogenesis. Nat Neurosci. 2008 Oct; 11(10):1137-9. PMID: 18758459; PMCID: PMC2574629.
    Citations: 100     Fields:    Translation:HumansAnimalsCells
  51. Gatchel JR, Watase K, Thaller C, Carson JP, Jafar-Nejad P, Shaw C, Zu T, Orr HT, Zoghbi HY. The insulin-like growth factor pathway is altered in spinocerebellar ataxia type 1 and type 7. Proc Natl Acad Sci U S A. 2008 Jan 29; 105(4):1291-6. PMID: 18216249.
    Citations: 44     Fields:    Translation:AnimalsCells
  52. Watase K, Gatchel JR, Sun Y, Emamian E, Atkinson R, Richman R, Mizusawa H, Orr HT, Shaw C, Zoghbi HY. Lithium therapy improves neurological function and hippocampal dendritic arborization in a spinocerebellar ataxia type 1 mouse model. PLoS Med. 2007 May; 4(5):e182. PMID: 17535104; PMCID: PMC1880853.
    Citations: 72     Fields:    Translation:AnimalsCells
  53. Gatchel JR, Zoghbi HY. Diseases of unstable repeat expansion: mechanisms and common principles. Nat Rev Genet. 2005 Oct; 6(10):743-55. PMID: 16205714.
    Citations: 327     Fields:    Translation:HumansCells
  54. Varga AW, Yuan LL, Anderson AE, Schrader LA, Wu GY, Gatchel JR, Johnston D, Sweatt JD. Calcium-calmodulin-dependent kinase II modulates Kv4.2 channel expression and upregulates neuronal A-type potassium currents. J Neurosci. 2004 Apr 07; 24(14):3643-54. PMID: 15071113; PMCID: PMC6729731.
    Citations: 68     Fields:    Translation:AnimalsCells
  55. Gazo BM, Murphy P, Gatchel JR, Browning KS. A novel interaction of Cap-binding protein complexes eukaryotic initiation factor (eIF) 4F and eIF(iso)4F with a region in the 3'-untranslated region of satellite tobacco necrosis virus. J Biol Chem. 2004 Apr 02; 279(14):13584-92. PMID: 14729906.
    Citations: 46     Fields:    Translation:Cells
  56. Bick RJ, Poindexter BJ, Tong S, Kalis NN, Van der Merwe P, Gatchel J, Young DC. Effects of IgM from rheumatic fever patients on intracellular calcium levels of neonatal rat cardiac myocytes. Life Sci. 2003 Sep 05; 73(16):2101-11. PMID: 12899933.
    Citations:    Fields:    Translation:HumansAnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.