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John Froehlich, Ph.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Wang HS, Cho PS, Zhi H, Kostel SA, DiMartino S, Dagher AM, Davis KH, Cabour LD, Shimmel A, Lee J, Froehlich JW, Zurakowski D, Moses MA, Lee RS. Association between urinary biomarkers MMP-7/TIMP-2 and reduced renal function in children with ureteropelvic junction obstruction. PLoS One. 2022; 17(7):e0270018. PMID: 35834547; PMCID: PMC9282603.
    Citations:    Fields:    Translation:Humans
  2. Froehlich JW, Wang HS, Logvinenko T, Kostel S, DiMartino S, van Bokhoven A, Moses MA, Lee RS. The Urinary Proteomic Profile Implicates Key Regulators for Urologic Chronic Pelvic Pain Syndrome (UCPPS): A MAPP Research Network Study. Mol Cell Proteomics. 2022 01; 21(1):100176. PMID: 34774759; PMCID: PMC8733275.
    Citations:    Fields:    Translation:Humans
  3. Daisy CC, Varinos S, Howell DR, Kaplan K, Mannix R, Meehan WP, Wang F, Berkstresser B, Lee RS, Froehlich JW, Zurakowski D, Moses MA. Proteomic Discovery of Noninvasive Biomarkers Associated With Sport-Related Concussions. Neurology. 2022 01 11; 98(2):e186-e198. PMID: 34675105; PMCID: PMC8762586.
    Citations: 1     Fields:    Translation:HumansCTClinical Trials
  4. Li H, Kostel SA, DiMartino SE, Hashemi Gheinani A, Froehlich JW, Lee RS. Uromodulin Isolation and Its N-Glycosylation Analysis by NanoLC-MS/MS. J Proteome Res. 2021 05 07; 20(5):2662-2672. PMID: 33650863.
    Citations: 1     Fields:    Translation:HumansCells
  5. Vitko D, Cho PS, Kostel SA, DiMartino SE, Cabour LD, Migliozzi MA, Logvinenko T, Warren PG, Froehlich JW, Lee RS. Characterizing Patients with Recurrent Urinary Tract Infections in Vesicoureteral Reflux: A Pilot Study of the Urinary Proteome. Mol Cell Proteomics. 2020 Mar; 19(3):456-466. PMID: 33451681.
    Citations:    Fields:    
  6. Roy R, Stephens AJ, Daisy C, Merritt L, Newcomb CW, Yang J, Dagher A, Curatolo A, Sachdev M, McNeish B, Landis R, van Bokhoven A, El-Hayek A, Froehlich J, Pontari MA, Zurakowski D, Lee RS, Moses MA. Association of Longitudinal Changes in Symptoms and Urinary Biomarkers in Patients with Urological Chronic Pelvic Pain Syndrome: A MAPP Research Network Study. J Urol. 2021 02; 205(2):514-523. PMID: 33026902; PMCID: PMC8139408.
    Citations: 2     Fields:    Translation:Humans
  7. De Leoz MLA, Duewer DL, Fung A, Liu L, Yau HK, Potter O, Staples GO, Furuki K, Frenkel R, Hu Y, Sosic Z, Zhang P, Altmann F, Grunwald-Grube C, Shao C, Zaia J, Evers W, Pengelley S, Suckau D, Wiechmann A, Resemann A, Jabs W, Beck A, Froehlich JW, Huang C, Li Y, Liu Y, Sun S, Wang Y, Seo Y, An HJ, Reichardt NC, Ruiz JE, Archer-Hartmann S, Azadi P, Bell L, Lakos Z, An Y, Cipollo JF, Pucic-Bakovic M, Štambuk J, Lauc G, Li X, Wang PG, Bock A, Hennig R, Rapp E, Creskey M, Cyr TD, Nakano M, Sugiyama T, Leung PA, Link-Lenczowski P, Jaworek J, Yang S, Zhang H, Kelly T, Klapoetke S, Cao R, Kim JY, Lee HK, Lee JY, Yoo JS, Kim SR, Suh SK, de Haan N, Falck D, Lageveen-Kammeijer GSM, Wuhrer M, Emery RJ, Kozak RP, Liew LP, Royle L, Urbanowicz PA, Packer NH, Song X, Everest-Dass A, Lattová E, Cajic S, Alagesan K, Kolarich D, Kasali T, Lindo V, Chen Y, Goswami K, Gau B, Amunugama R, Jones R, Stroop CJM, Kato K, Yagi H, Kondo S, Yuen CT, Harazono A, Shi X, Magnelli PE, Kasper BT, Mahal L, Harvey DJ, O'Flaherty R, Rudd PM, Saldova R, Hecht ES, Muddiman DC, Kang J, Bhoskar P, Menard D, Saati A, Merle C, Mast S, Tep S, Truong J, Nishikaze T, Sekiya S, Shafer A, Funaoka S, Toyoda M, de Vreugd P, Caron C, Pradhan P, Tan NC, Mechref Y, Patil S, Rohrer JS, Chakrabarti R, Dadke D, Lahori M, Zou C, Cairo C, Reiz B, Whittal RM, Lebrilla CB, Wu L, Guttman A, Szigeti M, Kremkow BG, Lee KH, Sihlbom C, Adamczyk B, Jin C, Karlsson NG, Örnros J, Larson G, Nilsson J, Meyer B, Wiegandt A, Komatsu E, Perreault H, Bodnar ED, Said N, Francois YN, Leize-Wagner E, Maier S, Zeck A, Heck AJR, Yang Y, Haselberg R, Yu YQ, Alley W, Leone JW, Yuan H, Stein SE. NIST Interlaboratory Study on Glycosylation Analysis of Monoclonal Antibodies: Comparison of Results from Diverse Analytical Methods. Mol Cell Proteomics. 2020 Jan; 19(1):11-30. PMID: 33451547.
    Citations:    Fields:    
  8. Li H, Patel V, DiMartino SE, Froehlich JW, Lee RS. An in-depth Comparison of the Pediatric and Adult Urinary N-glycomes. Mol Cell Proteomics. 2020 11; 19(11):1767-1776. PMID: 32737218.
    Citations: 2     Fields:    Translation:HumansCells
  9. Vitko D, Cho PS, Kostel SA, DiMartino SE, Cabour LD, Migliozzi MA, Logvinenko T, Warren PG, Froehlich JW, Lee RS. Characterizing Patients with Recurrent Urinary Tract Infections in Vesicoureteral Reflux: A Pilot Study of the Urinary Proteome. Mol Cell Proteomics. 2020 03; 19(3):456-466. PMID: 31896675.
    Citations: 4     Fields:    Translation:Humans
  10. De Leoz MLA, Duewer DL, Fung A, Liu L, Yau HK, Potter O, Staples GO, Furuki K, Frenkel R, Hu Y, Sosic Z, Zhang P, Altmann F, Grunwald-Grube C, Shao C, Zaia J, Evers W, Pengelley S, Suckau D, Wiechmann A, Resemann A, Jabs W, Beck A, Froehlich JW, Huang C, Li Y, Liu Y, Sun S, Wang Y, Seo Y, An HJ, Reichardt NC, Ruiz JE, Archer-Hartmann S, Azadi P, Bell L, Lakos Z, An Y, Cipollo JF, Pucic-Bakovic M, Štambuk J, Lauc G, Li X, Wang PG, Bock A, Hennig R, Rapp E, Creskey M, Cyr TD, Nakano M, Sugiyama T, Leung PA, Link-Lenczowski P, Jaworek J, Yang S, Zhang H, Kelly T, Klapoetke S, Cao R, Kim JY, Lee HK, Lee JY, Yoo JS, Kim SR, Suh SK, de Haan N, Falck D, Lageveen-Kammeijer GSM, Wuhrer M, Emery RJ, Kozak RP, Liew LP, Royle L, Urbanowicz PA, Packer NH, Song X, Everest-Dass A, Lattová E, Cajic S, Alagesan K, Kolarich D, Kasali T, Lindo V, Chen Y, Goswami K, Gau B, Amunugama R, Jones R, Stroop CJM, Kato K, Yagi H, Kondo S, Yuen CT, Harazono A, Shi X, Magnelli PE, Kasper BT, Mahal L, Harvey DJ, O'Flaherty R, Rudd PM, Saldova R, Hecht ES, Muddiman DC, Kang J, Bhoskar P, Menard D, Saati A, Merle C, Mast S, Tep S, Truong J, Nishikaze T, Sekiya S, Shafer A, Funaoka S, Toyoda M, de Vreugd P, Caron C, Pradhan P, Tan NC, Mechref Y, Patil S, Rohrer JS, Chakrabarti R, Dadke D, Lahori M, Zou C, Cairo C, Reiz B, Whittal RM, Lebrilla CB, Wu L, Guttman A, Szigeti M, Kremkow BG, Lee KH, Sihlbom C, Adamczyk B, Jin C, Karlsson NG, Örnros J, Larson G, Nilsson J, Meyer B, Wiegandt A, Komatsu E, Perreault H, Bodnar ED, Said N, Francois YN, Leize-Wagner E, Maier S, Zeck A, Heck AJR, Yang Y, Haselberg R, Yu YQ, Alley W, Leone JW, Yuan H, Stein SE. NIST Interlaboratory Study on Glycosylation Analysis of Monoclonal Antibodies: Comparison of Results from Diverse Analytical Methods. Mol Cell Proteomics. 2020 01; 19(1):11-30. PMID: 31591262; PMCID: PMC6944243.
    Citations: 27     Fields:    Translation:HumansCells
  11. Dagher A, Curatolo A, Sachdev M, Stephens AJ, Mullins C, Landis JR, van Bokhoven A, El-Hayek A, Froehlich JW, Briscoe AC, Roy R, Yang J, Pontari MA, Zurakowski D, Lee RS, Moses MA. Identification of novel non-invasive biomarkers of urinary chronic pelvic pain syndrome: findings from the Multidisciplinary Approach to the Study of Chronic Pelvic Pain (MAPP) Research Network. BJU Int. 2017 07; 120(1):130-142. PMID: 28263447.
    Citations: 16     Fields:    Translation:Humans
  12. Froehlich JW, Kostel SA, Cho PS, Briscoe AC, Steen H, Vaezzadeh AR, Lee RS. Urinary Proteomics Yield Pathological Insights for Ureteropelvic Junction Obstruction. Mol Cell Proteomics. 2016 08; 15(8):2607-15. PMID: 27215552.
    Citations: 8     Fields:    Translation:Humans
  13. Bennike T, Ayturk U, Haslauer CM, Froehlich JW, Proffen BL, Barnaby O, Birkelund S, Murray MM, Warman ML, Stensballe A, Steen H. A normative study of the synovial fluid proteome from healthy porcine knee joints. J Proteome Res. 2014 Oct 03; 13(10):4377-87. PMID: 25160569.
    Citations: 29     Fields:    Translation:AnimalsCells
  14. Zhou H, Warren PG, Froehlich JW, Lee RS. Dual modifications strategy to quantify neutral and sialylated N-glycans simultaneously by MALDI-MS. Anal Chem. 2014 Jul 01; 86(13):6277-84. PMID: 24766348.
    Citations: 12     Fields:    Translation:HumansAnimalsCells
  15. Zhou H, Froehlich JW, Briscoe AC, Lee RS. The GlycoFilter: a simple and comprehensive sample preparation platform for proteomics, N-glycomics and glycosylation site assignment. Mol Cell Proteomics. 2013 Oct; 12(10):2981-91. PMID: 23820512.
    Citations: 15     Fields:    Translation:HumansAnimalsCells
  16. Froehlich JW, Vaezzadeh AR, Kirchner M, Briscoe AC, Hofmann O, Hide W, Steen H, Lee RS. An in-depth comparison of the male pediatric and adult urinary proteomes. Biochim Biophys Acta. 2014 May; 1844(5):1044-50. PMID: 23707565.
    Citations: 6     Fields:    Translation:HumansCells
  17. Serang O, Froehlich JW, Muntel J, McDowell G, Steen H, Lee RS, Steen JA. SweetSEQer, simple de novo filtering and annotation of glycoconjugate mass spectra. Mol Cell Proteomics. 2013 Jun; 12(6):1735-40. PMID: 23443135.
    Citations: 9     Fields:    Translation:Humans
  18. Froehlich JW, Dodds ED, Wilhelm M, Serang O, Steen JA, Lee RS. A classifier based on accurate mass measurements to aid large scale, unbiased glycoproteomics. Mol Cell Proteomics. 2013 Apr; 12(4):1017-25. PMID: 23438733.
    Citations: 17     Fields:    Translation:HumansAnimalsCells
  19. Zhou H, Briscoe AC, Froehlich JW, Lee RS. PNGase F catalyzes de-N-glycosylation in a domestic microwave. Anal Biochem. 2012 Aug 01; 427(1):33-5. PMID: 22516523.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  20. Barboza M, Pinzon J, Wickramasinghe S, Froehlich JW, Moeller I, Smilowitz JT, Ruhaak LR, Huang J, Lönnerdal B, German JB, Medrano JF, Weimer BC, Lebrilla CB. Glycosylation of human milk lactoferrin exhibits dynamic changes during early lactation enhancing its role in pathogenic bacteria-host interactions. Mol Cell Proteomics. 2012 Jun; 11(6):M111.015248. PMID: 22261723.
    Citations: 49     Fields:    Translation:HumansCells
  21. Froehlich JW, Barboza M, Chu C, Lerno LA, Clowers BH, Zivkovic AM, German JB, Lebrilla CB. Nano-LC-MS/MS of glycopeptides produced by nonspecific proteolysis enables rapid and extensive site-specific glycosylation determination. Anal Chem. 2011 Jul 15; 83(14):5541-7. PMID: 21661761.
    Citations: 20     Fields:    Translation:HumansAnimalsCells
  22. Froehlich JW, Chu CS, Tang N, Waddell K, Grimm R, Lebrilla CB. Label-free liquid chromatography-tandem mass spectrometry analysis with automated phosphopeptide enrichment reveals dynamic human milk protein phosphorylation during lactation. Anal Biochem. 2011 Jan 01; 408(1):136-46. PMID: 20804719.
    Citations: 3     Fields:    Translation:HumansCells
  23. Froehlich JW, Dodds ED, Barboza M, McJimpsey EL, Seipert RR, Francis J, An HJ, Freeman S, German JB, Lebrilla CB. Glycoprotein expression in human milk during lactation. J Agric Food Chem. 2010 May 26; 58(10):6440-8. PMID: 20415418.
    Citations: 29     Fields:    Translation:HumansCells
  24. An HJ, Froehlich JW, Lebrilla CB. Determination of glycosylation sites and site-specific heterogeneity in glycoproteins. Curr Opin Chem Biol. 2009 Oct; 13(4):421-6. PMID: 19700364.
    Citations: 84     Fields:    Translation:HumansAnimalsCells
  25. Froehlich JE, Wilkerson CG, Ray WK, McAndrew RS, Osteryoung KW, Gage DA, Phinney BS. Proteomic study of the Arabidopsis thaliana chloroplastic envelope membrane utilizing alternatives to traditional two-dimensional electrophoresis. J Proteome Res. 2003 Jul-Aug; 2(4):413-25. PMID: 12938931.
    Citations: 77     Fields:    Translation:AnimalsCells
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