Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Sarah Uhler Morton, M.D.,Ph.D.

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Mentoring
Available: 01/10/22, Expires: 03/01/24

Congenital heart disease (CHD) is the most common severe malformation. As improvements in medical and surgical management have led to increased survival, patients with congenital heart disease face additional lifelong health risks. Neurodevelopmental delay or impairment is the most common extracardiac complication of CHD. To better understand the mechanisms of neurodevelopmental risk in patients with CHD, we have recently completed a clinical trial that collected genetic, clinical, and neuropsychological testing data. There are a broad range of potential analyses, and we would design a project together based on your interests.

Available: 01/10/22, Expires: 03/01/24

Nutrition has profound impact on neurodevelopment, but the mechanisms are only partly understood. We are studying the connections between maternal diet, breastmilk contents, infant brain development and child neurodevelopment. There are multiple analyses possible, and we would identify a focus together based on your interests.

Available: 12/02/22, Expires: 12/01/24

The group will focus on how early nutritional status affects neurodevelopment and health of infants with the goal of improving knowledge and personalized care through observational studies. Opportunities include computational projects analyzing brain MRI and machine learning models. Duration may be flexible - we will use a combination of your goals and your availability to craft a project that will result in a research product such as manuscript and/or meeting abstract.

Infant Feeding Ability [login at prompt]
Available: 12/02/22, Expires: 12/01/24

The group will focus on the how infant develop the important skill of oral feeding with the goal of improving diagnosis and personalized care through quantitative EMG assessment of infant feeding, advanced computational analytics, and identifying biomarkers of neonatal outcomes. Opportunities include computational projects, retrospective chart review, and work with patients. Duration may be flexible - we will use a combination of your goals and your availability to craft a project that will result in a research product such as manuscript and/or meeting abstract.

Available: 12/02/22, Expires: 12/01/24

The group will focus on the genetics of congenital heart disease with the goal of improving diagnosis and personalized care through gene discovery, functional analysis of patient variants, and identifying biomarkers of neonatal outcomes. Opportunities include computational biology projects, cell culture projects, and work with patient samples. Duration may be flexible - we will use a combination of your goals and your availability to craft a project that will result in a research product such as manuscript and/or meeting abstract.


Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Hehnly C, Shi A, Ssentongo P, Zhang L, Isaacs A, Morton SU, Streck N, Erdmann-Gilmore P, Tolstoy I, Townsend RR, Limbrick DD, Paulson JN, Ericson JE, Galperin MY, Schiff SJ, Broach JR. Type IV Pili Are a Critical Virulence Factor in Clinical Isolates of Paenibacillus thiaminolyticus. mBio. 2022 Nov 14; e0268822. PMID: 36374038.
    Citations:    Fields:    
  2. Patt E, Singhania A, Roberts AE, Morton SU. The genetics of neurodevelopment in congenital heart disease. Can J Cardiol. 2022 Sep 29. PMID: 36183910.
    Citations:    Fields:    
  3. Tung S, Heffernan J, Morton SU, Aziz-Bose R, Estroff JA. Fetal Disseminated Malignant Rhabdoid Tumor. Neoreviews. 2022 08 01; 23(8):e595-e602. PMID: 35909108.
    Citations:    Fields:    Translation:Humans
  4. Morton SU, Leyshon BJ, Tamilia E, Vyas R, Sisitsky M, Ladha I, Lasekan JB, Kuchan MJ, Grant PE, Ou Y. A Role for Data Science in Precision Nutrition and Early Brain Development. Front Psychiatry. 2022; 13:892259. PMID: 35815018; PMCID: PMC9259898.
    Citations:    
  5. Movassagh M, Morton SU, Hehnly C, Smith J, Doan TT, Irizarry R, Broach JR, Schiff SJ, Bailey JA, Paulson JN. mirTarRnaSeq: An R/Bioconductor Statistical Package for miRNA-mRNA Target Identification and Interaction Analysis. BMC Genomics. 2022 Jun 13; 23(1):439. PMID: 35698050; PMCID: PMC9191533.
    Citations:    Fields:    Translation:HumansCells
  6. Morton SU, Schnur M, Kerper R, Young V, O'Connell AE. Premature Infants Have Normal Maturation of the T Cell Receptor Repertoire at Term. Front Immunol. 2022; 13:854414. PMID: 35707545; PMCID: PMC9189380.
    Citations:    Fields:    Translation:Humans
  7. D'Souza EE, Vyas R, Sisitsky M, Feldman HA, Gagoski B, Litt J, Larsen RJ, Kuchan MJ, Lasekan JB, Sutton BP, Grant PE, Ou Y, Morton SU. Increased Breastfeeding Proportion Is Associated with Improved Gross Motor Skills at 3-5 Years of Age: A Pilot Study. Nutrients. 2022 May 26; 14(11). PMID: 35684014; PMCID: PMC9182886.
    Citations:    Fields:    Translation:Humans
  8. Quiat D, Kim SW, Zhang Q, Morton SU, Pereira AC, DePalma SR, Willcox JAL, McDonough B, DeLaughter DM, Gorham JM, Curran JJ, Tumblin M, Nicolau Y, Artunduaga MA, Quintanilla-Dieck L, Osorno G, Serrano L, Hamdan U, Eavey RD, Seidman CE, Seidman JG. An ancient founder mutation located between ROBO1 and ROBO2 is responsible for increased microtia risk in Amerindigenous populations. Proc Natl Acad Sci U S A. 2022 05 24; 119(21):e2203928119. PMID: 35584116; PMCID: PMC9173816.
    Citations:    Fields:    Translation:Humans
  9. Willcox JAL, Geiger JT, Morton SU, McKean D, Quiat D, Gorham JM, Tai AC, DePalma S, Bernstein D, Brueckner M, Chung WK, Giardini A, Goldmuntz E, Kaltman JR, Kim R, Newburger JW, Shen Y, Srivastava D, Tristani-Firouzi M, Gelb B, Porter GA, Seidman JG, Seidman CE. Neither cardiac mitochondrial DNA variation nor copy number contribute to congenital heart disease risk. Am J Hum Genet. 2022 05 05; 109(5):961-966. PMID: 35397206; PMCID: PMC9118105.
    Citations: 1     Fields:    Translation:HumansCells
  10. Morton SU, Christodoulou J, Costain G, Muntoni F, Wakeling E, Wojcik MH, French CE, Szuto A, Dowling JJ, Cohn RD, Raymond FL, Darras BT, Williams DA, Lunke S, Stark Z, Rowitch DH, Agrawal PB. Multicenter Consensus Approach to Evaluation of Neonatal Hypotonia in the Genomic Era: A Review. JAMA Neurol. 2022 04 01; 79(4):405-413. PMID: 35254387.
    Citations:    Fields:    Translation:Humans
  11. Gonzalez-Teran B, Pittman M, Felix F, Thomas R, Richmond-Buccola D, Hüttenhain R, Choudhary K, Moroni E, Costa MW, Huang Y, Padmanabhan A, Alexanian M, Lee CY, Maven BEJ, Samse-Knapp K, Morton SU, McGregor M, Gifford CA, Seidman JG, Seidman CE, Gelb BD, Colombo G, Conklin BR, Black BL, Bruneau BG, Krogan NJ, Pollard KS, Srivastava D. Transcription factor protein interactomes reveal genetic determinants in heart disease. Cell. 2022 03 03; 185(5):794-814.e30. PMID: 35182466; PMCID: PMC8923057.
    Citations: 1     Fields:    Translation:Animals
  12. Sen S, Levy PT, Hamrick SEG, Ali N, Osborne SW, Rios DR, Morton SU, Ashrafi AH, Backes CJ, McNamara PJ, Ball MK. Training pathways and careers for neonatologists interested in cardiovascular care. J Perinatol. 2022 04; 42(4):534-539. PMID: 35181763.
    Citations:    Fields:    Translation:Humans
  13. Hehnly C, Ssentongo P, Bebell LM, Burgoine K, Bazira J, Fronterre C, Kumbakumba E, Mulondo R, Mbabazi-Kabachelor E, Morton SU, Ngonzi J, Ochora M, Olupot-Olupot P, Mugamba J, Onen J, Roberts DJ, Sheldon K, Sinnar SA, Smith J, Ssenyonga P, Kiwanuka J, Paulson JN, Meier FA, Ericson JE, Broach JR, Schiff SJ. Cytomegalovirus infections in infants in Uganda: Newborn-mother pairs, neonates with sepsis, and infants with hydrocephalus. Int J Infect Dis. 2022 May; 118:24-33. PMID: 35150915; PMCID: PMC9058984.
    Citations:    Fields:    Translation:Humans
  14. Morton SU, Pereira AC, Quiat D, Richter F, Kitaygorodsky A, Hagen J, Bernstein D, Brueckner M, Goldmuntz E, Kim RW, Lifton RP, Porter GA, Tristani-Firouzi M, Chung WK, Roberts A, Gelb BD, Shen Y, Newburger JW, Seidman JG, Seidman CE. Genome-Wide De Novo Variants in Congenital Heart Disease Are Not Associated With Maternal Diabetes or Obesity. Circ Genom Precis Med. 2022 04; 15(2):e003500. PMID: 35130025; PMCID: PMC9295870.
    Citations: 1     Fields:    Translation:HumansCTClinical Trials
  15. Al-Hassan A, Vyas R, Zhang Y, Sisitsky M, Gagoski B, Litt JS, Larsen RJ, Kuchan MJ, Lasekan JB, Sutton BP, Grant PE, Ou Y, Morton SU. Assessment of Maternal Macular Pigment Optical Density (MPOD) as a Potential Marker for Dietary Carotenoid Intake during Lactation in Humans. Nutrients. 2021 Dec 31; 14(1). PMID: 35011057; PMCID: PMC8746783.
    Citations: 1     Fields:    Translation:Humans
  16. Morton SU, Labrecque M, Moline M, Hansen A, Leeman K. Reducing Benzodiazepine Exposure by Instituting a Guideline for Dexmedetomidine Usage in the NICU. Pediatrics. 2021 11 01; 148(5). PMID: 34982832.
    Citations:    Fields:    Translation:Humans
  17. Morton SU, Labrecque M, Moline M, Hansen A, Leeman K. Reducing Benzodiazepine Exposure by Instituting a Guideline for Dexmedetomidine Usage in the NICU. Pediatrics. 2021 11; 148(5). PMID: 34610948.
    Citations:    Fields:    Translation:Humans
  18. Morton SU, Maleyeff L, Wypij D, Yun HJ, Rollins CK, Watson CG, Newburger JW, Bellinger DC, Roberts AE, Rivkin MJ, Grant PE, Im K. Abnormal Right-Hemispheric Sulcal Patterns Correlate with Executive Function in Adolescents with Tetralogy of Fallot. Cereb Cortex. 2021 08 26; 31(10):4670-4680. PMID: 34009260; PMCID: PMC8408447.
    Citations: 1     Fields:    Translation:Humans
  19. Morton SU, Quiat D, Seidman JG, Seidman CE. Genomic frontiers in congenital heart disease. Nat Rev Cardiol. 2022 01; 19(1):26-42. PMID: 34272501; PMCID: PMC9236191.
    Citations: 12     Fields:    Translation:Humans
  20. Larsen RJ, Gagoski B, Morton SU, Ou Y, Vyas R, Litt J, Grant PE, Sutton BP. Quantification of magnetic resonance spectroscopy data using a combined reference: Application in typically developing infants. NMR Biomed. 2021 07; 34(7):e4520. PMID: 33913194.
    Citations: 2     Fields:    Translation:Humans
  21. Morton SU, Shimamura A, Newburger PE, Opotowsky AR, Quiat D, Pereira AC, Jin SC, Gurvitz M, Brueckner M, Chung WK, Shen Y, Bernstein D, Gelb BD, Giardini A, Goldmuntz E, Kim RW, Lifton RP, Porter GA, Srivastava D, Tristani-Firouzi M, Newburger JW, Seidman JG, Seidman CE. Association of Damaging Variants in Genes With Increased Cancer Risk Among Patients With Congenital Heart Disease. JAMA Cardiol. 2021 04 01; 6(4):457-462. PMID: 33084842; PMCID: PMC7578917.
    Citations: 10     Fields:    Translation:Humans
  22. Isaacs AM, Morton SU, Movassagh M, Zhang Q, Hehnly C, Zhang L, Morales DM, Sinnar SA, Ericson JE, Mbabazi-Kabachelor E, Ssenyonga P, Onen J, Mulondo R, Hornig M, Warf BC, Broach JR, Townsend RR, Limbrick DD, Paulson JN, Schiff SJ. Immune activation during Paenibacillus brain infection in African infants with frequent cytomegalovirus co-infection. iScience. 2021 Apr 23; 24(4):102351. PMID: 33912816; PMCID: PMC8065213.
    Citations: 1     
  23. Morton SU, Sefton CR, Zhang H, Dai M, Turner DL, Uhler MD, Agrawal PB. microRNA-mRNA Profile of Skeletal Muscle Differentiation and Relevance to Congenital Myotonic Dystrophy. Int J Mol Sci. 2021 Mar 07; 22(5). PMID: 33799993.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  24. Ward T, Tai W, Morton S, Impens F, Van Damme P, Van Haver D, Timmerman E, Venturini G, Zhang K, Jang MY, Willcox JAL, Haghighi A, Gelb BD, Chung WK, Goldmuntz E, Porter GA, Lifton RP, Brueckner M, Yost HJ, Bruneau BG, Gorham J, Kim Y, Pereira A, Homsy J, Benson CC, DePalma SR, Varland S, Chen CS, Arnesen T, Gevaert K, Seidman C, Seidman JG. Mechanisms of Congenital Heart Disease Caused by NAA15 Haploinsufficiency. Circ Res. 2021 04 16; 128(8):1156-1169. PMID: 33557580; PMCID: PMC8048381.
    Citations: 6     Fields:    Translation:HumansCellsCTClinical Trials
  25. Martin-Trujillo A, Patel N, Richter F, Jadhav B, Garg P, Morton SU, McKean DM, DePalma SR, Goldmuntz E, Gruber D, Kim R, Newburger JW, Porter GA, Giardini A, Bernstein D, Tristani-Firouzi M, Seidman JG, Seidman CE, Chung WK, Gelb BD, Sharp AJ. Rare genetic variation at transcription factor binding sites modulates local DNA methylation profiles. PLoS Genet. 2020 11; 16(11):e1009189. PMID: 33216750.
    Citations: 6     Fields:    Translation:HumansCells
  26. Sharma A, Wasson LK, Willcox JA, Morton SU, Gorham JM, DeLaughter DM, Neyazi M, Schmid M, Agarwal R, Jang MY, Toepfer CN, Ward T, Kim Y, Pereira AC, DePalma SR, Tai A, Kim S, Conner D, Bernstein D, Gelb BD, Chung WK, Goldmuntz E, Porter G, Tristani-Firouzi M, Srivastava D, Seidman JG, Seidman CE. GATA6 mutations in hiPSCs inform mechanisms for maldevelopment of the heart, pancreas, and diaphragm. Elife. 2020 10 15; 9. PMID: 33054971.
    Citations: 9     Fields:    Translation:HumansCells
  27. Paulson JN, Williams BL, Hehnly C, Mishra N, Sinnar SA, Zhang L, Ssentongo P, Mbabazi-Kabachelor E, Wijetunge DSS, von Bredow B, Mulondo R, Kiwanuka J, Bajunirwe F, Bazira J, Bebell LM, Burgoine K, Couto-Rodriguez M, Ericson JE, Erickson T, Ferrari M, Gladstone M, Guo C, Haran M, Hornig M, Isaacs AM, Kaaya BN, Kangere SM, Kulkarni AV, Kumbakumba E, Li X, Limbrick DD, Magombe J, Morton SU, Mugamba J, Ng J, Olupot-Olupot P, Onen J, Peterson MR, Roy F, Sheldon K, Townsend R, Weeks AD, Whalen AJ, Quackenbush J, Ssenyonga P, Galperin MY, Almeida M, Atkins H, Warf BC, Lipkin WI, Broach JR, Schiff SJ. Paenibacillus infection with frequent viral coinfection contributes to postinfectious hydrocephalus in Ugandan infants. Sci Transl Med. 2020 09 30; 12(563). PMID: 32998967; PMCID: PMC7774825.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  28. Morton SU, Brettin K, Feldman HA, Leeman KT. Association of nucleated red blood cell count with mortality among neonatal intensive care unit patients. Pediatr Neonatol. 2020 12; 61(6):592-597. PMID: 32771363.
    Citations: 2     Fields:    Translation:Humans
  29. Boskovski MT, Homsy J, Nathan M, Sleeper LA, Morton S, Manheimer KB, Tai A, Gorham J, Lewis M, Swartz M, Alfieris GM, Bacha EA, Karimi M, Meyer D, Nguyen K, Bernstein D, Romano-Adesman A, Porter GA, Goldmuntz E, Chung WK, Srivastava D, Kaltman JR, Tristani-Firouzi M, Lifton R, Roberts AE, Gaynor JW, Gelb BD, Kim R, Seidman JG, Brueckner M, Mayer JE, Newburger JW, Seidman CE. De Novo Damaging Variants, Clinical Phenotypes, and Post-Operative Outcomes in Congenital Heart Disease. Circ Genom Precis Med. 2020 08; 13(4):e002836. PMID: 32812804.
    Citations: 9     Fields:    Translation:HumansCells
  30. Richter F, Morton SU, Kim SW, Kitaygorodsky A, Wasson LK, Chen KM, Zhou J, Qi H, Patel N, DePalma SR, Parfenov M, Homsy J, Gorham JM, Manheimer KB, Velinder M, Farrell A, Marth G, Schadt EE, Kaltman JR, Newburger JW, Giardini A, Goldmuntz E, Brueckner M, Kim R, Porter GA, Bernstein D, Chung WK, Srivastava D, Tristani-Firouzi M, Troyanskaya OG, Dickel DE, Shen Y, Seidman JG, Seidman CE, Gelb BD. Genomic analyses implicate noncoding de novo variants in congenital heart disease. Nat Genet. 2020 08; 52(8):769-777. PMID: 32601476.
    Citations: 26     Fields:    Translation:HumansAnimalsCellsCTClinical Trials
  31. Morton SU, Agarwal R, Madden JA, Genetti CA, Brownstein CA, López-Giráldez F, Choi J, Seidman CE, Seidman JG, Lyon GJ, Agrawal PB. Congenital Heart Defects Due to TAF1 Missense Variants. Circ Genom Precis Med. 2020 06; 13(3):e002843. PMID: 32396742; PMCID: PMC7329268.
    Citations: 2     Fields:    Translation:Humans
  32. Hsieh A, Morton SU, Willcox JAL, Gorham JM, Tai AC, Qi H, DePalma S, McKean D, Griffin E, Manheimer KB, Bernstein D, Kim RW, Newburger JW, Porter GA, Srivastava D, Tristani-Firouzi M, Brueckner M, Lifton RP, Goldmuntz E, Gelb BD, Chung WK, Seidman CE, Seidman JG, Shen Y. EM-mosaic detects mosaic point mutations that contribute to congenital heart disease. Genome Med. 2020 04 29; 12(1):42. PMID: 32349777.
    Citations: 8     Fields:    Translation:Humans
  33. Morton SU, Vyas R, Gagoski B, Vu C, Litt J, Larsen RJ, Kuchan MJ, Lasekan JB, Sutton BP, Grant PE, Ou Y. Maternal Dietary Intake of Omega-3 Fatty Acids Correlates Positively with Regional Brain Volumes in 1-Month-Old Term Infants. Cereb Cortex. 2020 04 14; 30(4):2057-2069. PMID: 31711132.
    Citations: 9     Fields:    Translation:Humans
  34. Morton SU, Maleyeff L, Wypij D, Yun HJ, Newburger JW, Bellinger DC, Roberts AE, Rivkin MJ, Seidman JG, Seidman CE, Grant PE, Im K. Abnormal Left-Hemispheric Sulcal Patterns Correlate with Neurodevelopmental Outcomes in Subjects with Single Ventricular Congenital Heart Disease. Cereb Cortex. 2020 03 21; 30(2):476-487. PMID: 31216004.
    Citations: 7     Fields:    Translation:Humans
  35. Morton SU, Yuen JC, Feldman HA, Hashim E, Rudie C, Lindamood KE, Caughey D, Moline M, Sims JK, Sola-Visner MC, Leeman KT. Screening With Reticulocyte Hemoglobin Increased Iron Sufficiency Among NICU Patients. Pediatr Qual Saf. 2020 Mar-Apr; 5(2):e258. PMID: 32426625; PMCID: PMC7190262.
    Citations: 1     
  36. Barrero-Castillero A, Morton SU, Nelson CA, Smith VC. Psychosocial Stress and Adversity: Effects from the Perinatal Period to Adulthood. Neoreviews. 2019 12; 20(12):e686-e696. PMID: 31792156.
    Citations: 15     Fields:    Translation:Humans
  37. Richter F, Hoffman GE, Manheimer KB, Patel N, Sharp AJ, McKean D, Morton SU, DePalma S, Gorham J, Kitaygorodksy A, Porter GA, Giardini A, Shen Y, Chung WK, Seidman JG, Seidman CE, Schadt EE, Gelb BD. ORE identifies extreme expression effects enriched for rare variants. Bioinformatics. 2019 10 15; 35(20):3906-3912. PMID: 30903145.
    Citations: 1     Fields:    Translation:Humans
  38. Taylor JL, Debost JPG, Morton SU, Wigdor EM, Heyne HO, Lal D, Howrigan DP, Bloemendal A, Larsen JT, Kosmicki JA, Weiner DJ, Homsy J, Seidman JG, Seidman CE, Agerbo E, McGrath JJ, Mortensen PB, Petersen L, Daly MJ, Robinson EB. Paternal-age-related de novo mutations and risk for five disorders. Nat Commun. 2019 07 10; 10(1):3043. PMID: 31292440.
    Citations: 19     Fields:    Translation:Humans
  39. O'Connell AE, Gerashchenko MV, O'Donohue MF, Rosen SM, Huntzinger E, Gleeson D, Galli A, Ryder E, Cao S, Murphy Q, Kazerounian S, Morton SU, Schmitz-Abe K, Gladyshev VN, Gleizes PE, Séraphin B, Agrawal PB. Mammalian Hbs1L deficiency causes congenital anomalies and developmental delay associated with Pelota depletion and 80S monosome accumulation. PLoS Genet. 2019 02; 15(2):e1007917. PMID: 30707697; PMCID: PMC6373978.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  40. Minoche AE, Horvat C, Johnson R, Gayevskiy V, Morton SU, Drew AP, Woo K, Statham AL, Lundie B, Bagnall RD, Ingles J, Semsarian C, Seidman JG, Seidman CE, Dinger ME, Cowley MJ, Fatkin D. Response to Brodehl et al. Genet Med. 2019 05; 21(5):1248-1249. PMID: 30262924.
    Citations:    Fields:    Translation:HumansCells
  41. Shaaban S, MacKinnon S, Andrews C, Staffieri SE, Maconachie GDE, Chan WM, Whitman MC, Morton SU, Yazar S, MacGregor S, Elder JE, Traboulsi EI, Gottlob I, Hewitt AW, Hunter DG, Mackey DA, Engle EC. Genome-Wide Association Study Identifies a Susceptibility Locus for Comitant Esotropia and Suggests a Parent-of-Origin Effect. Invest Ophthalmol Vis Sci. 2018 08 01; 59(10):4054-4064. PMID: 30098192; PMCID: PMC6088800.
    Citations: 7     Fields:    Translation:Humans
  42. Minoche AE, Horvat C, Johnson R, Gayevskiy V, Morton SU, Drew AP, Woo K, Statham AL, Lundie B, Bagnall RD, Ingles J, Semsarian C, Seidman JG, Seidman CE, Dinger ME, Cowley MJ, Fatkin D. Genome sequencing as a first-line genetic test in familial dilated cardiomyopathy. Genet Med. 2019 03; 21(3):650-662. PMID: 29961767; PMCID: PMC7271716.
    Citations: 19     Fields:    Translation:HumansCells
  43. Morton SU, Belfort MB, Kahlon PS, Hajizadeh Barfjani S, Rudie C, Hashim E, Hansen A, Huh SY. Reducing time to initiation and advancement of enteral feeding in an all-referral neonatal intensive care unit. J Perinatol. 2018 07; 38(7):936-943. PMID: 29740193.
    Citations: 2     Fields:    Translation:Humans
  44. Jin SC, Homsy J, Zaidi S, Lu Q, Morton S, DePalma SR, Zeng X, Qi H, Chang W, Sierant MC, Hung WC, Haider S, Zhang J, Knight J, Bjornson RD, Castaldi C, Tikhonoa IR, Bilguvar K, Mane SM, Sanders SJ, Mital S, Russell MW, Gaynor JW, Deanfield J, Giardini A, Porter GA, Srivastava D, Lo CW, Shen Y, Watkins WS, Yandell M, Yost HJ, Tristani-Firouzi M, Newburger JW, Roberts AE, Kim R, Zhao H, Kaltman JR, Goldmuntz E, Chung WK, Seidman JG, Gelb BD, Seidman CE, Lifton RP, Brueckner M. Contribution of rare inherited and de novo variants in 2,871 congenital heart disease probands. Nat Genet. 2017 Nov; 49(11):1593-1601. PMID: 28991257.
    Citations: 250     Fields:    Translation:Humans
  45. Cao S, Smith LL, Padilla-Lopez SR, Guida BS, Blume E, Shi J, Morton SU, Brownstein CA, Beggs AH, Kruer MC, Agrawal PB. Homozygous EEF1A2 mutation causes dilated cardiomyopathy, failure to thrive, global developmental delay, epilepsy and early death. Hum Mol Genet. 2017 09 15; 26(18):3545-3552. PMID: 28911200; PMCID: PMC5886049.
    Citations: 10     Fields:    Translation:HumansAnimals
  46. Morton SU, Prabhu SP, Lidov HGW, Shi J, Anselm I, Brownstein CA, Bainbridge MN, Beggs AH, Vargas SO, Agrawal PB. AIFM1 mutation presenting with fatal encephalomyopathy and mitochondrial disease in an infant. Cold Spring Harb Mol Case Stud. 2017 03; 3(2):a001560. PMID: 28299359.
    Citations: 16     Fields:    Translation:HumansCells
  47. Morton SU, Neilan EG, Peake RWA, Shi J, Schmitz-Abe K, Towne M, Markianos K, Prabhu SP, Agrawal PB. Hyperammonemia as a Presenting Feature in Two Siblings with FBXL4 Variants. JIMD Rep. 2017; 35:7-15. PMID: 27858371; PMCID: PMC5585110.
    Citations: 3     
  48. Schiff SJ, Kiwanuka J, Riggio G, Nguyen L, Mu K, Sproul E, Bazira J, Mwanga-Amumpaire J, Tumusiime D, Nyesigire E, Lwanga N, Bogale KT, Kapur V, Broach JR, Morton SU, Warf BC, Poss M. Separating Putative Pathogens from Background Contamination with Principal Orthogonal Decomposition: Evidence for Leptospira in the Ugandan Neonatal Septisome. Front Med (Lausanne). 2016; 3:22. PMID: 27379237; PMCID: PMC4904006.
    Citations: 3     
  49. Morton SU, Brodsky D. Fetal Physiology and the Transition to Extrauterine Life. Clin Perinatol. 2016 Sep; 43(3):395-407. PMID: 27524443.
    Citations: 42     Fields:    Translation:Humans
  50. Morton SU, Smith VC. Treatment options for apnoea of prematurity. Arch Dis Child Fetal Neonatal Ed. 2016 Jul; 101(4):F352-6. PMID: 27010019.
    Citations: 12     Fields:    Translation:Humans
  51. Morton SU, Joshi M, Savic T, Beggs AH, Agrawal PB. Skeletal muscle microRNA and messenger RNA profiling in cofilin-2 deficient mice reveals cell cycle dysregulation hindering muscle regeneration. PLoS One. 2015; 10(4):e0123829. PMID: 25874796.
    Citations: 2     Fields:    Translation:Animals
  52. Cordes KR, Sheehy NT, White MP, Berry EC, Morton SU, Muth AN, Lee TH, Miano JM, Ivey KN, Srivastava D. miR-145 and miR-143 regulate smooth muscle cell fate and plasticity. Nature. 2009 Aug 06; 460(7256):705-10. PMID: 19578358; PMCID: PMC2769203.
    Citations: 703     Fields:    Translation:AnimalsCells
  53. Morton SU, Scherz PJ, Cordes KR, Ivey KN, Stainier DY, Srivastava D. microRNA-138 modulates cardiac patterning during embryonic development. Proc Natl Acad Sci U S A. 2008 Nov 18; 105(46):17830-5. PMID: 19004786.
    Citations: 85     Fields:    Translation:AnimalsCells
  54. Fish JE, Santoro MM, Morton SU, Yu S, Yeh RF, Wythe JD, Ivey KN, Bruneau BG, Stainier DY, Srivastava D. miR-126 regulates angiogenic signaling and vascular integrity. Dev Cell. 2008 Aug; 15(2):272-84. PMID: 18694566; PMCID: PMC2604134.
    Citations: 690     Fields:    Translation:HumansAnimalsCells
  55. Mitchell DA, Morton SU, Fernhoff NB, Marletta MA. Thioredoxin is required for S-nitrosation of procaspase-3 and the inhibition of apoptosis in Jurkat cells. Proc Natl Acad Sci U S A. 2007 Jul 10; 104(28):11609-14. PMID: 17606900; PMCID: PMC1913894.
    Citations: 64     Fields:    Translation:HumansCells
  56. Anderson FW, Morton SU, Naik S, Gebrian B. Maternal mortality and the consequences on infant and child survival in rural Haiti. Matern Child Health J. 2007 Jul; 11(4):395-401. PMID: 17265193.
    Citations: 23     Fields:    Translation:Humans
  57. Mitchell DA, Morton SU, Marletta MA. Design and characterization of an active site selective caspase-3 transnitrosating agent. ACS Chem Biol. 2006 Nov 21; 1(10):659-65. PMID: 17168570.
    Citations: 4     Fields:    Translation:HumansCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.