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Joel Adler, M.D.

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Biography
University of Wisconsin, MadisonBA05/2005Spanish Languages and Literature
University of Wisconsin School of Medicine and Public Health, MadisonMD05/2010
Harvard T. H. Chan School of Public Health, BostonMPH05/2015

Overview
I am a kidney and pancreas transplant surgeon at Brigham and Women's Hospital, where my clinical practice is dedicated to clinical care, teaching, research, and service to the community of patients with end stage organ disease. My research is devoted to enhancing access to transplantation by ameliorating disparities, incentivizing more efficient utilization of organs, and improving transplantation as a healthcare system to ensure a fair and equitable process for all.

My areas of expertise include health services research in transplantation that translate to actionable items in national organ allocation policy. My work has focused on economic incentives and market competition among transplant centers in a geographic area; as the national organ allocation policies have changed, this work was featured prominently in the discussions of how transplant centers would behave under different geographic sharing arrangements. Past training in Geographic Information Systems has enabled study of the role that geography, density, and distance play in this complex system.

A significant portion of my clinical time is spent teaching residents and medical students about kidney and pancreas transplantation. This includes teaching on rounds, in formal and informal lectures, and in the operating room. I also spend a considerable amount of time mentoring and teaching research fellows in my role as core faculty at the Center for Surgery and Public Health at Brigham and Women's Hospital. Clinically, my expertise is in patients who are particularly difficult to transplant due to immunologic barriers, as well as patients who are surgically challenging due to technical reasons.

Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. ASTS-CareDx Enhancing Organ Donation and Transplan (Joel T. Adler, MD, MPH) Jul 1, 2020 - Jun 30, 2022
    American Society of Transplant Surgeons
    Development of the Hospital Organ donation Performance Score (HOPS)
    Role Description: The goal of this study is to devise an innovative, risk-adjusted score to rank deceased organ donor hospital performance. By using this score, we hope to define targets for quality improvement to increase deceased organ donation.
    Role: Principal Investigator

Featured Content

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Castillo-Angeles M, Li G, Bain PA, Stinebring J, Salim A, Adler JT. Systematic review of hospital-level metrics and interventions to increase deceased organ donation. Transplant Rev (Orlando). 2021 Mar 06; 35(3):100613. PMID: 33744820.
    Citations:    Fields:    
  2. Efe O, McGrath MM, Hu FY, Ramanathan V, Cotton RT, Adler JT, Azzi J. Urinoma From Surgical Cyst Rupture and Page Kidney Phenomenon in a Kidney Transplant Recipient. Kidney Med. 2021 Mar-Apr; 3(2):307-308. PMID: 33851129.
    Citations:    
  3. Sokas C, Cooper Z, Salim A, Rodrigue JR, Adler JT. Wait expectations: The impact of delisting as an outcome from the kidney transplant waitlist. Clin Transplant. 2021 Feb 09; e14250. PMID: 33565145.
    Citations:    Fields:    
  4. Diamond JM, Courtwright AM, Balar P, Oyster M, Zaleski D, Adler J, Brown M, Hays SR, Sutter N, Garvey C, Kukreja J, Gao Y, Bruun A, Smith PJ, Singer JP. Mobile health technology to improve emergent frailty after lung transplantation. Clin Transplant. 2021 Apr; 35(4):e14236. PMID: 33527520.
    Citations:    Fields:    
  5. Adler JT, Tsai TC, Jin G, Cron DC, Ross-Driscoll KH, Malek SK, Tullius SG, Weissman JS. Association of balanced abdominal organ transplant center volumes with patient outcomes. Clin Transplant. 2021 Apr; 35(4):e14217. PMID: 33405324.
    Citations:    Fields:    
  6. Adler JT, Husain SA, King KL, Mohan S. Greater complexity and monitoring of the new Kidney Allocation System: Implications and unintended consequences of concentric circle kidney allocation on network complexity. Am J Transplant. 2020 Dec 12. PMID: 33314637.
    Citations:    Fields:    
  7. Bababekov YJ, Hung YC, Chang DC, Rickert CG, Adler JT, Bethea E, Pomfret EA, Pomposelli JJ, Yeh H. Do Social Determinants Define "Too Sick" to Transplant in Patients With End-stage Liver Disease? Transplantation. 2020 02; 104(2):280-284. PMID: 31335769.
    Citations:    Fields:    Translation:Humans
  8. Adler JT, Redfield RR, Kaufman DB, Odorico JS. Isolated pancreas transplantation: Is rank list position related to outcomes of imported grafts? Am J Transplant. 2019 11; 19(11):3124-3130. PMID: 30963706.
    Citations:    Fields:    Translation:HumansCTClinical Trials
  9. Adler JT, Zaborek N, Redfield RR, Kaufman DB, Odorico JS, Sollinger HW. Enteric conversion after bladder-drained pancreas transplantation is not associated with worse allograft survival. Am J Transplant. 2019 09; 19(9):2543-2549. PMID: 30838785.
    Citations: 2     Fields:    Translation:Humans
  10. Henderson ML, Adler JT, Van Pilsum Rasmussen SE, Thomas AG, Herron PD, Waldram MM, Ruck JM, Purnell TS, DiBrito SR, Holscher CM, Haugen CE, Alimi Y, Konel JM, Eno AK, Garonzik Wang JM, Gordon EJ, Lentine KL, Schaffer RL, Cameron AM, Segev DL. How Should Social Media Be Used in Transplantation? A Survey of the American Society of Transplant Surgeons. Transplantation. 2019 03; 103(3):573-580. PMID: 29684002.
    Citations: 2     Fields:    Translation:Humans
  11. Bababekov YJ, Hung YC, Rickert CG, Njoku FC, Cao B, Adler JT, Brega AG, Pomposelli JJ, Chang DC, Yeh H. Health Literacy Burden Is Associated With Access to Liver Transplantation. Transplantation. 2019 03; 103(3):522-528. PMID: 30431496.
    Citations: 1     Fields:    Translation:Humans
  12. Michelakos T, Xourafas D, Qadan M, Pieretti-Vanmarcke R, Cai L, Patel MS, Adler JT, Fontan F, Basit U, Vagefi PA, Elias N, Tanabe KK, Berger D, Yeh H, Markmann JF, Chang DC, Ferrone CR. Hepatocellular Carcinoma in Transplantable Child-Pugh A Cirrhotics: Should Cost Affect Resection vs Transplantation? J Gastrointest Surg. 2019 06; 23(6):1135-1142. PMID: 30218342.
    Citations: 1     Fields:    Translation:Humans
  13. Cao B, Adler JT, Bababekov YJ, Markmann JF, Chang DC, Yeh H. Pediatric kidney transplantation and mortality: Distance to transplant center matters. Pediatr Transplant. 2018 03; 22(2). PMID: 29316061.
    Citations: 2     Fields:    Translation:Humans
  14. Mueller JL, Guyer RA, Adler JT, Mullen JT. Metastatic renal cell carcinoma to the small bowel: three cases of GI bleeding and a literature review. CEN Case Rep. 2018 May; 7(1):39-43. PMID: 29185198.
    Citations: 2     Fields:    
  15. Adler JT, Yeh H, Barbesino G, Lubitz CC. Reassessing risks and benefits of living kidney donors with a history of thyroid cancer. Clin Transplant. 2017 Nov; 31(11). PMID: 28963768.
    Citations: 1     Fields:    Translation:Humans
  16. Alvino DML, Chang DC, Adler JT, Noorbakhsh A, Jin G, Mullen JT. How Far Are Patients Willing to Travel for Gastrectomy? Ann Surg. 2017 06; 265(6):1172-1177. PMID: 27280507.
    Citations: 11     Fields:    Translation:Humans
  17. Subramanian A, Adler JT, Shah ND, Hyder JA. Hospital Rating Systems and Implications For Patient Travel to Better-rated Hospitals. Ann Surg. 2017 03; 265(3):e23-e25. PMID: 27849669.
    Citations:    Fields:    Translation:Humans
  18. Olufajo OA, Adler JT, Yeh H, Zeliadt SB, Hernandez RA, Tullius SG, Backhus L, Salim A. Disparities in kidney transplantation across the United States: Does residential segregation play a role? Am J Surg. 2017 Apr; 213(4):656-661. PMID: 28228248.
    Citations:    Fields:    Translation:Humans
  19. Adler JT, Bababekov YJ, Markmann JF, Chang DC, Yeh H. Distance is associated with mortality on the waitlist in pediatric liver transplantation. Pediatr Transplant. 2017 Mar; 21(2). PMID: 27804189.
    Citations: 3     Fields:    Translation:Humans
  20. Adler JT, Chang DC, Chan AT, Faiz O, Maguire LH. Seasonal Variation in Diverticulitis: Evidence From Both Hemispheres. Dis Colon Rectum. 2016 Sep; 59(9):870-7. PMID: 27505116.
    Citations: 3     Fields:    Translation:Humans
  21. Adler JT, Markmann JF, Yeh H. Renal allograft thrombosis after living donor transplantation: risk factors and obstacles to retransplantation. Clin Transplant. 2016 08; 30(8):864-71. PMID: 27101358.
    Citations: 2     Fields:    Translation:Humans
  22. Adler JT, Chang DC. Implications of Market Competition, Technology Adoption, and Cost for Surgical Patients. JAMA Surg. 2016 07 01; 151(7):621. PMID: 26886881.
    Citations: 2     Fields:    Translation:Humans
  23. Adler JT, Yeh H, Markmann JF, Axelrod DA. Is Donor Service Area Market Competition Associated With Organ Procurement Organization Performance? Transplantation. 2016 06; 100(6):1349-55. PMID: 26516674.
    Citations: 2     Fields:    Translation:Humans
  24. Adler JT, Hyder JA, Markmann JF, Axelrod DA, Yeh H. Socioeconomic gradients between locally transplanted and exported liver donors and recipients. Liver Transpl. 2016 Apr; 22(4):557-8. PMID: 26845498.
    Citations:    Fields:    Translation:Humans
  25. Adler JT, Yeh H, Markmann JF, Nguyen LL. Temporal Analysis of Market Competition and Density in Renal Transplantation Volume and Outcome. Transplantation. 2016 Mar; 100(3):670-7. PMID: 26574684.
    Citations: 1     Fields:    Translation:Humans
  26. Adler JT, Axelrod DA. Regulations' Impact on Donor and Recipient Selection for Liver Transplantation: How Should Outcomes be Measured and MELD Exception Scores be Considered? AMA J Ethics. 2016 Feb 01; 18(2):133-42. PMID: 26894809.
    Citations: 1     Fields:    Translation:Humans
  27. Adler JT, Yeh H. Social determinants in liver transplantation. Clin Liver Dis (Hoboken). 2016 Jan; 7(1):15-17. PMID: 31041019.
    Citations: 1     
  28. Adler JT, Yeh H. Identification of Race and Ethnicity in Large Databases. JAMA Surg. 2015 Nov; 150(11):1099. PMID: 26287810.
    Citations:    Fields:    Translation:Humans
  29. Adler JT, Yeh H, Markmann JF, Nguyen LL. Market Competition and Density in Liver Transplantation: Relationship to Volume and Outcomes. J Am Coll Surg. 2015 Aug; 221(2):524-31. PMID: 26206649.
    Citations: 1     Fields:    Translation:Humans
  30. Adler JT, Dong N, Markmann JF, Schoenfeld D, Yeh H. Role of Patient Factors and Practice Patterns in Determining Access to Liver Waitlist. Am J Transplant. 2015 Jul; 15(7):1836-42. PMID: 25931200.
    Citations: 4     Fields:    Translation:Humans
  31. Hyder JA, Wakeam E, Adler JT, DeBord Smith A, Lipsitz SR, Nguyen LL. Comparing Preoperative Targets to Failure-to-Rescue for Surgical Mortality Improvement. J Am Coll Surg. 2015 Jun; 220(6):1096-106. PMID: 25863680.
    Citations: 2     Fields:    Translation:Humans
  32. Adler JT, Hyder JA, Elias N, Nguyen LL, Markmann JF, Delmonico FL, Yeh H. Socioeconomic status and ethnicity of deceased donor kidney recipients compared to their donors. Am J Transplant. 2015 Apr; 15(4):1061-7. PMID: 25758952.
    Citations: 2     Fields:    Translation:Humans
  33. Adler JT, Sethi RK, Yeh H, Markmann JF, Nguyen LL. Market competition influences renal transplantation risk and outcomes. Ann Surg. 2014 Sep; 260(3):550-6; discussion 556-7. PMID: 25115431.
    Citations: 5     Fields:    Translation:Humans
  34. Adler JT, Chen H, Schaefer S, Sippel RS. What is the added benefit of cervical ultrasound to ??mTc-sestamibi scanning in primary hyperparathyroidism? Ann Surg Oncol. 2011 Oct; 18(10):2907-11. PMID: 21509629.
    Citations: 5     Fields:    Translation:Humans
  35. Adler JT, Sippel RS, Chen H. New trends in parathyroid surgery. Curr Probl Surg. 2010 Dec; 47(12):958-1017. PMID: 21044730.
    Citations: 14     Fields:    Translation:Humans
  36. Adler JT, Chen H, Schaefer S, Sippel RS. Does routine use of ultrasound result in additional thyroid procedures in patients with primary hyperparathyroidism? J Am Coll Surg. 2010 Oct; 211(4):536-9. PMID: 20822743.
    Citations: 8     Fields:    Translation:Humans
  37. Adler JT, Sippel RS, Chen H. 25-hydroxyvitamin D status does not affect intraoperative parathyroid hormone dynamics in patients with primary hyperparathyroidism. Ann Surg Oncol. 2010 Nov; 17(11):2958-62. PMID: 20544293.
    Citations: 5     Fields:    Translation:Humans
  38. Adler JT, Chen H. Is endocrine surgery research dying? Am J Transl Res. 2010 Feb 15; 2(2):129-34. PMID: 20407602.
    Citations: 2     
  39. Adler JT, Hottinger DG, Kunnimalaiyaan M, Chen H. Inhibition of the PI3K pathway suppresses hormonal secretion and limits growth in pheochromocytoma cells. World J Surg. 2009 Nov; 33(11):2452-7. PMID: 19669229.
    Citations: 4     Fields:    Translation:HumansCells
  40. Ballian N, Adler JT, Sippel RS, Chen H. Revisiting adrenal mass size as an indication for adrenalectomy. J Surg Res. 2009 Sep; 156(1):16-20. PMID: 19592028.
    Citations: 4     Fields:    Translation:Humans
  41. Adler JT, Cook M, Luo Y, Pitt SC, Ju J, Li W, Shen B, Kunnimalaiyaan M, Chen H. Tautomycetin and tautomycin suppress the growth of medullary thyroid cancer cells via inhibition of glycogen synthase kinase-3beta. . 2009 Apr; 8(4):914-20. PMID: 19372564.
    Citations: 15     Translation:HumansCells
  42. Pinchot SN, Adler JT, Luo Y, Ju J, Li W, Shen B, Kunnimalaiyaan M, Chen H. Tautomycin suppresses growth and neuroendocrine hormone markers in carcinoid cells through activation of the Raf-1 pathway. Am J Surg. 2009 Mar; 197(3):313-9. PMID: 19245907.
    Citations: 9     Fields:    Translation:HumansCells
  43. Adler JT, Sippel RS, Schaefer S, Chen H. Surgery improves quality of life in patients with "mild" hyperparathyroidism. Am J Surg. 2009 Mar; 197(3):284-90. PMID: 19245902.
    Citations: 13     Fields:    Translation:Humans
  44. Adler JT, Hottinger DG, Kunnimalaiyaan M, Chen H. Histone deacetylase inhibitors upregulate Notch-1 and inhibit growth in pheochromocytoma cells. Surgery. 2008 Dec; 144(6):956-61; discussion 961-2. PMID: 19041003.
    Citations: 19     Fields:    Translation:AnimalsCells
  45. Adler JT, Hottinger DG, Kunnimalaiyaan M, Chen H. Combination therapy with histone deacetylase inhibitors and lithium chloride: a novel treatment for carcinoid tumors. Ann Surg Oncol. 2009 Feb; 16(2):481-6. PMID: 19030935.
    Citations: 17     Fields:    Translation:HumansCells
  46. Adler JT, Sippel RS, Schaefer S, Chen H. Preserving function and quality of life after thyroid and parathyroid surgery. Lancet Oncol. 2008 Nov; 9(11):1069-75. PMID: 19012855.
    Citations: 10     Fields:    Translation:Humans
  47. Adler JT, Hottinger DG, Kunnimalaiyaan M, Chen H. Inhibition of growth in medullary thyroid cancer cells with histone deacetylase inhibitors and lithium chloride. J Surg Res. 2010 Apr; 159(2):640-4. PMID: 19394967.
    Citations: 12     Fields:    Translation:HumansCells
  48. Zhang YW, Greenblatt DY, Repplinger D, Bargren A, Adler JT, Sippel RS, Chen H. Older age and larger tumor size predict malignancy in hürthle cell neoplasms of the thyroid. Ann Surg Oncol. 2008 Oct; 15(10):2842-6. PMID: 18665423.
    Citations: 16     Fields:    Translation:Humans
  49. Adler JT, Meyer-Rochow GY, Chen H, Benn DE, Robinson BG, Sippel RS, Sidhu SB. Pheochromocytoma: current approaches and future directions. Oncologist. 2008 Jul; 13(7):779-93. PMID: 18617683.
    Citations: 55     Fields:    Translation:Humans
  50. Greenblatt DY, Cayo MA, Adler JT, Ning L, Haymart MR, Kunnimalaiyaan M, Chen H. Valproic acid activates Notch1 signaling and induces apoptosis in medullary thyroid cancer cells. Ann Surg. 2008 Jun; 247(6):1036-40. PMID: 18520232.
    Citations: 36     Fields:    Translation:HumansCells
  51. Adler JT, Sippel RS, Chen H. The influence of surgical approach on quality of life after parathyroid surgery. Ann Surg Oncol. 2008 Jun; 15(6):1559-65. PMID: 18379849.
    Citations: 3     Fields:    Translation:Humans
  52. Repplinger D, Bargren A, Zhang YW, Adler JT, Haymart M, Chen H. Is Hashimoto's thyroiditis a risk factor for papillary thyroid cancer? J Surg Res. 2008 Nov; 150(1):49-52. PMID: 17996901.
    Citations: 62     Fields:    Translation:Humans
  53. Egan KR, Adler JT, Olson JE, Chen H. Parathyroidectomy for primary hyperparathyroidism in octogenarians and nonagenarians: a risk-benefit analysis. J Surg Res. 2007 Jun 15; 140(2):194-8. PMID: 17509264.
    Citations: 14     Fields:    Translation:Humans
  54. Adler JT, Mack E, Chen H. Isolated adrenal mass in patients with a history of cancer: remember pheochromocytoma. Ann Surg Oncol. 2007 Aug; 14(8):2358-62. PMID: 17505857.
    Citations: 8     Fields:    Translation:Humans
  55. Adler JT, Mack E, Chen H. Equal oncologic results for laparoscopic and open resection of adrenal metastases. J Surg Res. 2007 Jun 15; 140(2):159-64. PMID: 17196989.
    Citations: 13     Fields:    Translation:Humans
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.