Harvard Catalyst Profiles

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Katherine S Yang, Ph.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Fraser K, Jo A, Giedt J, Vinegoni C, Yang KS, Peruzzi P, Chiocca EA, Breakefield XO, Lee H, Weissleder R. Characterization of single microvesicles in plasma from glioblastoma patients. Neuro Oncol. 2019 May 06; 21(5):606-615. PMID: 30561734.
    Citations:    Fields:    
  2. Yang KS, Im H, Hong S, Pergolini I, Del Castillo AF, Wang R, Clardy S, Huang CH, Pille C, Ferrone S, Yang R, Castro CM, Lee H, Del Castillo CF, Weissleder R. Multiparametric plasma EV profiling facilitates diagnosis of pancreatic malignancy. Sci Transl Med. 2017 05 24; 9(391). PMID: 28539469.
    Citations: 8     Fields:    Translation:Humans
  3. Arlauckas SP, Garris CS, Kohler RH, Kitaoka M, Cuccarese MF, Yang KS, Miller MA, Carlson JC, Freeman GJ, Anthony RM, Weissleder R, Pittet MJ. In vivo imaging reveals a tumor-associated macrophage-mediated resistance pathway in anti-PD-1 therapy. Sci Transl Med. 2017 05 10; 9(389). PMID: 28490665.
    Citations: 23     Fields:    Translation:HumansAnimalsCells
  4. Giedt RJ, Fumene Feruglio P, Pathania D, Yang KS, Kilcoyne A, Vinegoni C, Mitchison TJ, Weissleder R. Computational imaging reveals mitochondrial morphology as a biomarker of cancer phenotype and drug response. Sci Rep. 2016 09 09; 6:32985. PMID: 27609668.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  5. Miller MA, Gadde S, Pfirschke C, Engblom C, Sprachman MM, Kohler RH, Yang KS, Laughney AM, Wojtkiewicz G, Kamaly N, Bhonagiri S, Pittet MJ, Farokhzad OC, Weissleder R. Predicting therapeutic nanomedicine efficacy using a companion magnetic resonance imaging nanoparticle. Sci Transl Med. 2015 Nov 18; 7(314):314ra183. PMID: 26582898.
    Citations: 41     Fields:    Translation:HumansAnimalsCells
  6. Miller MA, Zheng YR, Gadde S, Pfirschke C, Zope H, Engblom C, Kohler RH, Iwamoto Y, Yang KS, Askevold B, Kolishetti N, Pittet M, Lippard SJ, Farokhzad OC, Weissleder R. Tumour-associated macrophages act as a slow-release reservoir of nano-therapeutic Pt(IV) pro-drug. Nat Commun. 2015 Oct 27; 6:8692. PMID: 26503691.
    Citations: 39     Fields:    Translation:HumansAnimalsCells
  7. Kim E, Yang KS, Kohler RH, Dubach JM, Mikula H, Weissleder R. Optimized Near-IR Fluorescent Agents for in Vivo Imaging of Btk Expression. Bioconjug Chem. 2015 Aug 19; 26(8):1513-8. PMID: 26017814.
    Citations: 9     Fields:    Translation:HumansCells
  8. Yang KS, Kohler RH, Landon M, Giedt R, Weissleder R. Single cell resolution in vivo imaging of DNA damage following PARP inhibition. Sci Rep. 2015 May 18; 5:10129. PMID: 25984718.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  9. Giedt RJ, Sprachman MM, Yang KS, Weissleder R. Imaging cellular distribution of Bcl inhibitors using small molecule drug conjugates. Bioconjug Chem. 2014 Nov 19; 25(11):2081-5. PMID: 25333750.
    Citations: 1     Fields:    Translation:HumansCells
  10. Kim E, Yang KS, Giedt RJ, Weissleder R. Red Si-rhodamine drug conjugates enable imaging in GFP cells. Chem Commun (Camb). 2014 May 04; 50(34):4504-7. PMID: 24663433.
    Citations: 7     Fields:    Translation:HumansCells
  11. Thurber GM, Reiner T, Yang KS, Kohler RH, Weissleder R. Effect of small-molecule modification on single-cell pharmacokinetics of PARP inhibitors. Mol Cancer Ther. 2014 Apr; 13(4):986-95. PMID: 24552776.
    Citations: 18     Fields:    Translation:HumansAnimalsCells
  12. Miller MA, Askevold B, Yang KS, Kohler RH, Weissleder R. Platinum compounds for high-resolution in vivo cancer imaging. ChemMedChem. 2014 Jun; 9(6):1131-5. PMID: 24504646.
    Citations: 12     Fields:    Translation:HumansAnimalsCells
  13. Kim E, Yang KS, Weissleder R. Bioorthogonal small molecule imaging agents allow single-cell imaging of MET. PLoS One. 2013; 8(11):e81275. PMID: 24265843.
    Citations: 7     Fields:    Translation:HumansCells
  14. Yang KS, Budin G, Tassa C, Kister O, Weissleder R. Bioorthogonal approach to identify unsuspected drug targets in live cells. Angew Chem Int Ed Engl. 2013 Sep 27; 52(40):10593-7. PMID: 23960025.
    Citations: 7     Fields:    Translation:Humans
  15. Yang KS, Budin G, Reiner T, Vinegoni C, Weissleder R. Bioorthogonal imaging of aurora kinase A in live cells. Angew Chem Int Ed Engl. 2012 Jul 02; 51(27):6598-603. PMID: 22644700.
    Citations: 23     Fields:    Translation:Humans
  16. Reiner T, Lacy J, Keliher EJ, Yang KS, Ullal A, Kohler RH, Vinegoni C, Weissleder R. Imaging therapeutic PARP inhibition in vivo through bioorthogonally developed companion imaging agents. Neoplasia. 2012 Mar; 14(3):169-77. PMID: 22496617.
    Citations: 39     Fields:    Translation:HumansAnimalsCells
  17. Adak S, Yang KS, Macdonald-Obermann J, Pike LJ. The membrane-proximal intracellular domain of the epidermal growth factor receptor underlies negative cooperativity in ligand binding. J Biol Chem. 2011 Dec 30; 286(52):45146-55. PMID: 22069315.
    Citations: 11     Fields:    Translation:HumansAnimalsCells
  18. Ullal AV, Reiner T, Yang KS, Gorbatov R, Min C, Issadore D, Lee H, Weissleder R. Nanoparticle-mediated measurement of target-drug binding in cancer cells. ACS Nano. 2011 Nov 22; 5(11):9216-24. PMID: 21962084.
    Citations: 3     Fields:    Translation:HumansCells
  19. Budin G, Yang KS, Reiner T, Weissleder R. Bioorthogonal probes for polo-like kinase 1 imaging and quantification. Angew Chem Int Ed Engl. 2011 Sep 26; 50(40):9378-81. PMID: 21948435.
    Citations: 19     Fields:    Translation:HumansCells
  20. Yang KS, Macdonald-Obermann JL, Piwnica-Worms D, Pike LJ. Asp-960/Glu-961 controls the movement of the C-terminal tail of the epidermal growth factor receptor to regulate asymmetric dimer formation. J Biol Chem. 2010 Jul 30; 285(31):24014-22. PMID: 20507979.
    Citations: 5     Fields:    Translation:AnimalsCells
  21. Yang RY, Yang KS, Pike LJ, Marshall GR. Targeting the dimerization of epidermal growth factor receptors with small-molecule inhibitors. Chem Biol Drug Des. 2010 Jul; 76(1):1-9. PMID: 20456371.
    Citations: 7     Fields:    Translation:HumansCells
  22. Marzinke MA, Henderson EM, Yang KS, See AW, Knutson DC, Clagett-Dame M. Calmin expression in embryos and the adult brain, and its regulation by all-trans retinoic acid. Dev Dyn. 2010 Feb; 239(2):610-9. PMID: 20014094.
    Citations:    Fields:    Translation:AnimalsCells
  23. Yang KS, Ilagan MX, Piwnica-Worms D, Pike LJ. Luciferase fragment complementation imaging of conformational changes in the epidermal growth factor receptor. J Biol Chem. 2009 Mar 20; 284(12):7474-82. PMID: 19171934.
    Citations: 23     Fields:    Translation:AnimalsCells
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Funded by the NIH/NCATS Clinical and Translational Science Award (CTSA) program, grant number UL1TR001102, and through institutional support from Harvard University, Harvard Medical School, Harvard T.H. Chan School of Public Health, Beth Israel Deaconess Medical Center, Boston Children's Hospital, Brigham and Women's Hospital, Massachusetts General Hospital and the Dana Farber Cancer Institute.