Harvard Catalyst Profiles

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Katherine S Yang, Ph.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Surucu Y, Bengur FB, Yang KS, Schilling BK, Baker JS, Shabbir S, Fisher R, Epperly MW, Greenberger JS, Rubin JP, Ejaz A. Establishment of a Robust and Reproducible Model of Radiation-Induced Skin and Muscle Fibrosis. J Vis Exp. 2022 08 31; (186). PMID: 36121259.
    Citations:    Fields:    Translation:HumansAnimals
  2. Ferguson S, Yang KS, Weissleder R. Single extracellular vesicle analysis for early cancer detection. Trends Mol Med. 2022 08; 28(8):681-692. PMID: 35624008; PMCID: PMC9339504.
    Citations:    Fields:    
  3. Ferguson S, Yang KS, Zelga P, Liss AS, Carlson JCT, Del Castillo CF, Weissleder R. Single-EV analysis (sEVA) of mutated proteins allows detection of stage 1 pancreatic cancer. Sci Adv. 2022 04 22; 8(16):eabm3453. PMID: 35452280; PMCID: PMC9032977.
    Citations:    Fields:    Translation:HumansCells
  4. Chinnapaka S, Yang KS, Flowers Q, Faisal M, Nerone WV, Rubin JP, Ejaz A. Metformin Improves Stemness of Human Adipose-Derived Stem Cells by Downmodulation of Mechanistic Target of Rapamycin (mTOR) and Extracellular Signal-Regulated Kinase (ERK) Signaling. Biomedicines. 2021 Nov 27; 9(12). PMID: 34944598.
    Citations: 1     
  5. Chinnapaka S, Yang KS, Samadi Y, Epperly MW, Hou W, Greenberger JS, Ejaz A, Rubin JP. Allogeneic adipose-derived stem cells mitigate acute radiation syndrome by the rescue of damaged bone marrow cells from apoptosis. Stem Cells Transl Med. 2021 07; 10(7):1095-1114. PMID: 33724714; PMCID: PMC8235137.
    Citations: 3     Fields:    Translation:AnimalsCellsPHPublic Health
  6. Yang KS, Ciprani D, O'Shea A, Liss AS, Yang R, Fletcher-Mercaldo S, Mino-Kenudson M, Fern√°ndez-Del Castillo C, Weissleder R. Extracellular Vesicle Analysis Allows for Identification of Invasive IPMN. Gastroenterology. 2021 03; 160(4):1345-1358.e11. PMID: 33301777; PMCID: PMC7956058.
    Citations: 14     Fields:    Translation:HumansAnimalsCells
  7. Ejaz A, Yang KS, Venkatesh KP, Chinnapaka S, Kokai LE, Rubin JP. The Impact of Human Lipoaspirate and Adipose Tissue-Derived Stem Cells Contact Culture on Breast Cancer Cells: Implications in Breast Reconstruction. Int J Mol Sci. 2020 Dec 01; 21(23). PMID: 33271950.
    Citations: 3     Fields:    Translation:HumansCells
  8. Yang KS, Lin HY, Curley C, Welch MW, Wolpin BM, Lee H, Weissleder R, Im H, Castro CM. Bead-Based Extracellular Vesicle Analysis Using Flow Cytometry. Adv Biosyst. 2020 12; 4(12):e2000203. PMID: 33103361; PMCID: PMC7718389.
    Citations: 3     Fields:    Translation:HumansCells
  9. Fraser K, Jo A, Giedt J, Vinegoni C, Yang KS, Peruzzi P, Chiocca EA, Breakefield XO, Lee H, Weissleder R. Characterization of single microvesicles in plasma from glioblastoma patients. Neuro Oncol. 2019 05 06; 21(5):606-615. PMID: 30561734.
    Citations: 34     Fields:    Translation:HumansAnimalsCells
  10. Yang KS, Im H, Hong S, Pergolini I, Del Castillo AF, Wang R, Clardy S, Huang CH, Pille C, Ferrone S, Yang R, Castro CM, Lee H, Del Castillo CF, Weissleder R. Multiparametric plasma EV profiling facilitates diagnosis of pancreatic malignancy. Sci Transl Med. 2017 05 24; 9(391). PMID: 28539469.
    Citations: 81     Fields:    Translation:Humans
  11. Arlauckas SP, Garris CS, Kohler RH, Kitaoka M, Cuccarese MF, Yang KS, Miller MA, Carlson JC, Freeman GJ, Anthony RM, Weissleder R, Pittet MJ. In vivo imaging reveals a tumor-associated macrophage-mediated resistance pathway in anti-PD-1 therapy. Sci Transl Med. 2017 05 10; 9(389). PMID: 28490665; PMCID: PMC5734617.
    Citations: 230     Fields:    Translation:HumansAnimalsCells
  12. Giedt RJ, Fumene Feruglio P, Pathania D, Yang KS, Kilcoyne A, Vinegoni C, Mitchison TJ, Weissleder R. Computational imaging reveals mitochondrial morphology as a biomarker of cancer phenotype and drug response. Sci Rep. 2016 09 09; 6:32985. PMID: 27609668.
    Citations: 25     Fields:    Translation:HumansAnimalsCells
  13. Miller MA, Gadde S, Pfirschke C, Engblom C, Sprachman MM, Kohler RH, Yang KS, Laughney AM, Wojtkiewicz G, Kamaly N, Bhonagiri S, Pittet MJ, Farokhzad OC, Weissleder R. Predicting therapeutic nanomedicine efficacy using a companion magnetic resonance imaging nanoparticle. Sci Transl Med. 2015 Nov 18; 7(314):314ra183. PMID: 26582898.
    Citations: 113     Fields:    Translation:HumansAnimalsCells
  14. Miller MA, Zheng YR, Gadde S, Pfirschke C, Zope H, Engblom C, Kohler RH, Iwamoto Y, Yang KS, Askevold B, Kolishetti N, Pittet M, Lippard SJ, Farokhzad OC, Weissleder R. Tumour-associated macrophages act as a slow-release reservoir of nano-therapeutic Pt(IV) pro-drug. Nat Commun. 2015 Oct 27; 6:8692. PMID: 26503691; PMCID: PMC4711745.
    Citations: 135     Fields:    Translation:HumansAnimalsCells
  15. Kim E, Yang KS, Kohler RH, Dubach JM, Mikula H, Weissleder R. Optimized Near-IR Fluorescent Agents for in Vivo Imaging of Btk Expression. Bioconjug Chem. 2015 Aug 19; 26(8):1513-8. PMID: 26017814; PMCID: PMC4772718.
    Citations: 22     Fields:    Translation:HumansCells
  16. Yang KS, Kohler RH, Landon M, Giedt R, Weissleder R. Single cell resolution in vivo imaging of DNA damage following PARP inhibition. Sci Rep. 2015 May 18; 5:10129. PMID: 25984718.
    Citations: 24     Fields:    Translation:HumansAnimalsCells
  17. Giedt RJ, Sprachman MM, Yang KS, Weissleder R. Imaging cellular distribution of Bcl inhibitors using small molecule drug conjugates. Bioconjug Chem. 2014 Nov 19; 25(11):2081-5. PMID: 25333750.
    Citations: 3     Fields:    Translation:HumansCells
  18. Kim E, Yang KS, Giedt RJ, Weissleder R. Red Si-rhodamine drug conjugates enable imaging in GFP cells. Chem Commun (Camb). 2014 May 04; 50(34):4504-7. PMID: 24663433.
    Citations: 12     Fields:    Translation:HumansCells
  19. Thurber GM, Reiner T, Yang KS, Kohler RH, Weissleder R. Effect of small-molecule modification on single-cell pharmacokinetics of PARP inhibitors. Mol Cancer Ther. 2014 Apr; 13(4):986-95. PMID: 24552776.
    Citations: 26     Fields:    Translation:HumansAnimalsCells
  20. Miller MA, Askevold B, Yang KS, Kohler RH, Weissleder R. Platinum compounds for high-resolution in vivo cancer imaging. ChemMedChem. 2014 Jun; 9(6):1131-5. PMID: 24504646.
    Citations: 26     Fields:    Translation:HumansAnimalsCells
  21. Kim E, Yang KS, Weissleder R. Bioorthogonal small molecule imaging agents allow single-cell imaging of MET. PLoS One. 2013; 8(11):e81275. PMID: 24265843.
    Citations: 8     Fields:    Translation:HumansCells
  22. Yang KS, Budin G, Tassa C, Kister O, Weissleder R. Bioorthogonal approach to identify unsuspected drug targets in live cells. Angew Chem Int Ed Engl. 2013 Sep 27; 52(40):10593-7. PMID: 23960025.
    Citations: 16     Fields:    Translation:Humans
  23. Yang KS, Budin G, Reiner T, Vinegoni C, Weissleder R. Bioorthogonal imaging of aurora kinase A in live cells. Angew Chem Int Ed Engl. 2012 Jul 02; 51(27):6598-603. PMID: 22644700; PMCID: PMC3523717.
    Citations: 29     Fields:    Translation:Humans
  24. Reiner T, Lacy J, Keliher EJ, Yang KS, Ullal A, Kohler RH, Vinegoni C, Weissleder R. Imaging therapeutic PARP inhibition in vivo through bioorthogonally developed companion imaging agents. Neoplasia. 2012 Mar; 14(3):169-77. PMID: 22496617.
    Citations: 59     Fields:    Translation:HumansAnimalsCells
  25. Adak S, Yang KS, Macdonald-Obermann J, Pike LJ. The membrane-proximal intracellular domain of the epidermal growth factor receptor underlies negative cooperativity in ligand binding. J Biol Chem. 2011 Dec 30; 286(52):45146-55. PMID: 22069315.
    Citations: 13     Fields:    Translation:HumansAnimalsCells
  26. Ullal AV, Reiner T, Yang KS, Gorbatov R, Min C, Issadore D, Lee H, Weissleder R. Nanoparticle-mediated measurement of target-drug binding in cancer cells. ACS Nano. 2011 Nov 22; 5(11):9216-24. PMID: 21962084.
    Citations: 7     Fields:    Translation:HumansCells
  27. Budin G, Yang KS, Reiner T, Weissleder R. Bioorthogonal probes for polo-like kinase 1 imaging and quantification. Angew Chem Int Ed Engl. 2011 Sep 26; 50(40):9378-81. PMID: 21948435; PMCID: PMC3187564.
    Citations: 27     Fields:    Translation:HumansCells
  28. Yang KS, Macdonald-Obermann JL, Piwnica-Worms D, Pike LJ. Asp-960/Glu-961 controls the movement of the C-terminal tail of the epidermal growth factor receptor to regulate asymmetric dimer formation. J Biol Chem. 2010 Jul 30; 285(31):24014-22. PMID: 20507979.
    Citations: 6     Fields:    Translation:AnimalsCells
  29. Yang RY, Yang KS, Pike LJ, Marshall GR. Targeting the dimerization of epidermal growth factor receptors with small-molecule inhibitors. Chem Biol Drug Des. 2010 Jul; 76(1):1-9. PMID: 20456371.
    Citations: 12     Fields:    Translation:HumansCells
  30. Marzinke MA, Henderson EM, Yang KS, See AW, Knutson DC, Clagett-Dame M. Calmin expression in embryos and the adult brain, and its regulation by all-trans retinoic acid. Dev Dyn. 2010 Feb; 239(2):610-9. PMID: 20014094.
    Citations: 2     Fields:    Translation:AnimalsCells
  31. Yang KS, Ilagan MX, Piwnica-Worms D, Pike LJ. Luciferase fragment complementation imaging of conformational changes in the epidermal growth factor receptor. J Biol Chem. 2009 Mar 20; 284(12):7474-82. PMID: 19171934.
    Citations: 25     Fields:    Translation:AnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.