Harvard Catalyst Profiles

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Jennifer Lo, M.D.

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Research
research activities and funding
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  1. F30ES025626 (LO, JENNIFER A) May 1, 2015 - Apr 30, 2017
    NIH
    The roles of UV, neoantigens, and epitope spreading in vitiligo and melanoma
    Role: Principal Investigator

Bibliographic
selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Trinidad J, Gabel CK, Han JJ, Bonomo L, Cartron A, Chand S, Coburn W, Daveluy S, Davis M, DeNiro KL, Guggina LM, Hennessy K, Hoffman M, Katz K, Keller JJ, Kim SJ, Konda S, Lake E, Lincoln FN, Lo JA, Markova A, Marvin EK, Micheletti RG, Newman S, Nutan FNU, Nguyen CV, Pahalyants V, Patel J, Rahnama-Moghadam S, Rambhatla PV, Riegert M, Reingold RE, Robinson DB, Rrapi R, Sartori-Valinotti JC, Seminario-Vidal L, Sharif-Sidi Z, Smogorzewski J, Spaccarelli N, Stewart JR, Tuttle SD, Ulrich MN, Wanat KA, Di Xia F, Kaffenberger B, Kroshinsky D. Telemedicine and dermatology hospital consultations during the COVID-19 pandemic: a multi-centre observational study on resource utilization and conversion to in-person consultations during the COVID-19 pandemic. J Eur Acad Dermatol Venereol. 2022 05; 36(5):e323-e325. PMID: 34932237.
    Citations:    Fields:    Translation:HumansPHPublic Health
  2. Yokoyama S, Takahashi A, Kikuchi R, Nishibu S, Lo JA, Hejna M, Moon WM, Kato S, Zhou Y, Hodi FS, Song JS, Sakurai H, Fisher DE, Hayakawa Y. SOX10 Regulates Melanoma Immunogenicity through an IRF4-IRF1 Axis. Cancer Res. 2021 12 15; 81(24):6131-6141. PMID: 34728538; PMCID: PMC8678351.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  3. Rrapi R, Chand S, Lo JA, Gabel CK, Song S, Holcomb Z, Iriarte C, Moore K, Shi CR, Song H, Xia FD, Yanes D, Gandhi R, Triant VA, Kroshinsky D. The significance of exanthems in COVID-19 patients hospitalized at a tertiary care centre. J Eur Acad Dermatol Venereol. 2021 Oct; 35(10):e640-e642. PMID: 34146347; PMCID: PMC8447347.
    Citations:    Fields:    Translation:HumansCells
  4. Rrapi R, Chand S, Gaffney R, Lo JA, Smith JS, Xia FD, Chen ST, Duncan LM, Foreman RK, Hartman RI, Hoang MP, Piris A, Walls AC, Kroshinsky D. Cutaneous mucormycosis arising in the skin folds of immunocompromised patients: A case series. JAAD Case Rep. 2021 Nov; 17:92-95. PMID: 34746347; PMCID: PMC8551783.
    Citations: 1     
  5. Allouche J, Rachmin I, Adhikari K, Pardo LM, Lee JH, McConnell AM, Kato S, Fan S, Kawakami A, Suita Y, Wakamatsu K, Igras V, Zhang J, Navarro PP, Lugo CM, Noonan HR, Christie KA, Itin K, Mujahid N, Lo JA, Won CH, Evans CL, Weng QY, Wang H, Osseiran S, Lovas A, Németh I, Cozzio A, Navarini AA, Hsiao JJ, Nguyen N, Kemény LV, Iliopoulos O, Berking C, Ruzicka T, Gonzalez-José R, Bortolini MC, Canizales-Quinteros S, Acuna-Alonso V, Gallo C, Poletti G, Bedoya G, Rothhammer F, Ito S, Schiaffino MV, Chao LH, Kleinstiver BP, Tishkoff S, Zon LI, Nijsten T, Ruiz-Linares A, Fisher DE, Roider E. NNT mediates redox-dependent pigmentation via a UVB- and MITF-independent mechanism. Cell. 2021 08 05; 184(16):4268-4283.e20. PMID: 34233163; PMCID: PMC8349839.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  6. Kemény LV, Robinson KC, Hermann AL, Walker DM, Regan S, Yew YW, Lai YC, Theodosakis N, Rivera PD, Ding W, Yang L, Beyer T, Loh YE, Lo JA, van der Sande AAJ, Sarnie W, Kotler D, Hsiao JJ, Su MY, Kato S, Kotler J, Bilbo SD, Chopra V, Salomon MP, Shen S, Hoon DSB, Asgari MM, Wakeman SE, Nestler EJ, Fisher DE. Vitamin D deficiency exacerbates UV/endorphin and opioid addiction. Sci Adv. 2021 06; 7(24). PMID: 34117054; PMCID: PMC8195487.
    Citations: 4     Fields:    Translation:HumansAnimals
  7. Rrapi R, Chand S, Lo JA, Gabel CK, Song S, Holcomb Z, Iriarte C, Moore K, Shi CR, Song H, Di Xia F, Yanes D, Gandhi R, Triant VA, Kroshinsky D. The significance of pressure injuries and purpura in COVID-19 patients hospitalized at a large urban academic medical center: A retrospective cohort study. J Am Acad Dermatol. 2021 08; 85(2):462-464. PMID: 33753253; PMCID: PMC7979268.
    Citations:    Fields:    Translation:HumansCells
  8. Lo JA, Kawakubo M, Juneja VR, Su MY, Erlich TH, LaFleur MW, Kemeny LV, Rashid M, Malehmir M, Rabi SA, Raghavan R, Allouche J, Kasumova G, Frederick DT, Pauken KE, Weng QY, Pereira da Silva M, Xu Y, van der Sande AAJ, Silkworth W, Roider E, Browne EP, Lieb DJ, Wang B, Garraway LA, Wu CJ, Flaherty KT, Brinckerhoff CE, Mullins DW, Adams DJ, Hacohen N, Hoang MP, Boland GM, Freeman GJ, Sharpe AH, Manstein D, Fisher DE. Epitope spreading toward wild-type melanocyte-lineage antigens rescues suboptimal immune checkpoint blockade responses. Sci Transl Med. 2021 02 17; 13(581). PMID: 33597266.
    Citations: 20     Fields:    Translation:HumansAnimalsCells
  9. Chand S, Rrapi R, Lo JA, Song S, Gabel CK, Desai N, Hoang MP, Kroshinsky D. Purpuric ulcers associated with COVID-19: A case series. JAAD Case Rep. 2021 May; 11:13-19. PMID: 33558846; PMCID: PMC7857020.
    Citations: 2     
  10. Elowitz M, Sivaraman B, Hendrix A, Lo JI, Chou SL, Cheng BM, Sekhar BNR, Mason NJ. Possible detection of hydrazine on Saturn's moon Rhea. Sci Adv. 2021 Jan; 7(4). PMID: 33523937.
    Citations:    Fields:    
  11. Kato S, Weng QY, Insco ML, Chen KY, Muralidhar S, Pozniak J, Diaz JMS, Drier Y, Nguyen N, Lo JA, van Rooijen E, Kemeny LV, Zhan Y, Feng Y, Silkworth W, Powell CT, Liau BB, Xiong Y, Jin J, Newton-Bishop J, Zon LI, Bernstein BE, Fisher DE. Gain-of-Function Genetic Alterations of G9a Drive Oncogenesis. Cancer Discov. 2020 07; 10(7):980-997. PMID: 32269030; PMCID: PMC7334057.
    Citations: 16     Fields:    Translation:HumansCells
  12. Rosenbaum SR, Knecht M, Mollaee M, Zhong Z, Erkes DA, McCue PA, Chervoneva I, Berger AC, Lo JA, Fisher DE, Gershenwald JE, Davies MA, Purwin TJ, Aplin AE. FOXD3 Regulates VISTA Expression in Melanoma. Cell Rep. 2020 01 14; 30(2):510-524.e6. PMID: 31940493; PMCID: PMC6995351.
    Citations: 18     Fields:    Translation:HumansAnimalsCells
  13. Chen ST, Molina GE, Lo JA, Durbin S, Cohen JV, Reynolds KL, Kroshinsky D. Dermatology consultation reduces interruption of oncologic management among hospitalized patients with immune-related adverse events: A retrospective cohort study. J Am Acad Dermatol. 2020 04; 82(4):994-996. PMID: 31560981.
    Citations: 8     Fields:    Translation:Humans
  14. Chow MT, Ozga AJ, Servis RL, Frederick DT, Lo JA, Fisher DE, Freeman GJ, Boland GM, Luster AD. Intratumoral Activity of the CXCR3 Chemokine System Is Required for the Efficacy of Anti-PD-1 Therapy. Immunity. 2019 06 18; 50(6):1498-1512.e5. PMID: 31097342.
    Citations: 157     Fields:    Translation:HumansAnimalsCells
  15. Manguso RT, Pope HW, Zimmer MD, Brown FD, Yates KB, Miller BC, Collins NB, Bi K, LaFleur MW, Juneja VR, Weiss SA, Lo J, Fisher DE, Miao D, Van Allen E, Root DE, Sharpe AH, Doench JG, Haining WN. In vivo CRISPR screening identifies Ptpn2 as a cancer immunotherapy target. Nature. 2017 07 27; 547(7664):413-418. PMID: 28723893; PMCID: PMC5924693.
    Citations: 346     Fields:    Translation:HumansAnimalsCells
  16. Lo JA, Fisher DE, Flaherty KT. Prognostic Significance of Cutaneous Adverse Events Associated With Pembrolizumab Therapy. JAMA Oncol. 2015 Dec; 1(9):1340-1. PMID: 26270186; PMCID: PMC4679487.
    Citations: 25     Fields:    Translation:Humans
  17. Lo JA, Fisher DE. The melanoma revolution: from UV carcinogenesis to a new era in therapeutics. Science. 2014 Nov 21; 346(6212):945-9. PMID: 25414302.
    Citations: 147     Fields:    Translation:HumansCells
  18. Miller SB, Yildiz FZ, Lo JA, Wang B, D'Souza VM. A structure-based mechanism for tRNA and retroviral RNA remodelling during primer annealing. Nature. 2014 Nov 27; 515(7528):591-5. PMID: 25209668.
    Citations: 23     Fields:    Translation:HumansAnimalsCells
  19. Cooper ZA, Juneja VR, Sage PT, Frederick DT, Piris A, Mitra D, Lo JA, Hodi FS, Freeman GJ, Bosenberg MW, McMahon M, Flaherty KT, Fisher DE, Sharpe AH, Wargo JA. Response to BRAF inhibition in melanoma is enhanced when combined with immune checkpoint blockade. Cancer Immunol Res. 2014 Jul; 2(7):643-54. PMID: 24903021.
    Citations: 118     Fields:    Translation:HumansAnimalsCells
  20. Mitra D, Luo X, Morgan A, Wang J, Hoang MP, Lo J, Guerrero CR, Lennerz JK, Mihm MC, Wargo JA, Robinson KC, Devi SP, Vanover JC, D'Orazio JA, McMahon M, Bosenberg MW, Haigis KM, Haber DA, Wang Y, Fisher DE. An ultraviolet-radiation-independent pathway to melanoma carcinogenesis in the red hair/fair skin background. Nature. 2012 Nov 15; 491(7424):449-53. PMID: 23123854.
    Citations: 160     Fields:    Translation:AnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.