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Emiri T Mandeville, Ph.D., M.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Esposito E, Li W, Mandeville ET, Park JH, Sencan I, Guo S, Shi J, Lan J, Lee J, Hayakawa K, Sakadžic S, Ji X, Lo EH. Author Correction: Potential circadian effects on translational failure for neuroprotection. Nature. 2020 Jul; 583(7814):E14. PMID: 32533095.
    Citations:    
  2. Esposito E, Ahn BJ, Shi J, Nakamura Y, Park JH, Mandeville ET, Yu Z, Chan SJ, Desai R, Hayakawa A, Ji X, Lo EH, Hayakawa K. Brain-to-cervical lymph node signaling after stroke. Nat Commun. 2019 11 22; 10(1):5306. PMID: 31757960.
    Citations:    
  3. Lim TC, Mandeville E, Weng D, Wang LS, Kurisawa M, Leite-Morris K, Selim MH, Lo EH, Spector M. Hydrogel-Based Therapy for Brain Repair After Intracerebral Hemorrhage. Transl Stroke Res. 2020 Jun; 11(3):412-417. PMID: 31432328.
    Citations:    
  4. Hayakawa K, Chan SJ, Mandeville ET, Park JH, Bruzzese M, Montaner J, Arai K, Rosell A, Lo EH. Protective Effects of Endothelial Progenitor Cell-Derived Extracellular Mitochondria in Brain Endothelium. Stem Cells. 2018 09; 36(9):1404-1410. PMID: 29781122.
    Citations: 3     Fields:    
  5. Cooley CZ, Mandeville JB, Mason EE, Mandeville ET, Wald LL. Rodent Cerebral Blood Volume (CBV) changes during hypercapnia observed using Magnetic Particle Imaging (MPI) detection. Neuroimage. 2018 09; 178:713-720. PMID: 29738908.
    Citations:    Fields:    
  6. Lu D, Jiang Y, Ji Y, Zhou IY, Mandeville E, Lo EH, Wang X, Sun PZ. JOURNAL CLUB: Evaluation of Diffusion Kurtosis Imaging of Stroke Lesion With Hemodynamic and Metabolic MRI in a Rodent Model of Acute Stroke. AJR Am J Roentgenol. 2018 Apr; 210(4):720-727. PMID: 29470156.
    Citations:    Fields:    
  7. Maki T, Choi YK, Miyamoto N, Shindo A, Liang AC, Ahn BJ, Mandeville ET, Kaji S, Itoh K, Seo JH, Gelman IH, Lok J, Takahashi R, Kim KW, Lo EH, Arai K. A-Kinase Anchor Protein 12 Is Required for Oligodendrocyte Differentiation in Adult White Matter. Stem Cells. 2018 05; 36(5):751-760. PMID: 29314444.
    Citations: 2     Fields:    
  8. Yang S, Gu C, Mandeville ET, Dong Y, Esposito E, Zhang Y, Yang G, Shen Y, Fu X, Lo EH, Xie Z. Anesthesia and Surgery Impair Blood-Brain Barrier and Cognitive Function in Mice. Front Immunol. 2017; 8:902. PMID: 28848542.
    Citations: 3     
  9. Zhou IY, Guo Y, Igarashi T, Wang Y, Mandeville E, Chan ST, Wen L, Vangel M, Lo EH, Ji X, Sun PZ. Fast diffusion kurtosis imaging (DKI) with Inherent COrrelation-based Normalization (ICON) enhances automatic segmentation of heterogeneous diffusion MRI lesion in acute stroke. NMR Biomed. 2016 12; 29(12):1670-1677. PMID: 27696558.
    Citations: 4     Fields:    Translation:Animals
  10. Choi YK, Maki T, Mandeville ET, Koh SH, Hayakawa K, Arai K, Kim YM, Whalen MJ, Xing C, Wang X, Kim KW, Lo EH. Dual effects of carbon monoxide on pericytes and neurogenesis in traumatic brain injury. Nat Med. 2016 11; 22(11):1335-1341. PMID: 27668935.
    Citations: 12     Fields:    Translation:HumansAnimalsCells
  11. Mandeville ET, Ayata C, Zheng Y, Mandeville JB. Translational MR Neuroimaging of Stroke and Recovery. Transl Stroke Res. 2017 02; 8(1):22-32. PMID: 27578048.
    Citations: 5     Fields:    Translation:HumansAnimals
  12. Fujiwara N, Som AT, Pham LD, Lee BJ, Mandeville ET, Lo EH, Arai K. A free radical scavenger edaravone suppresses systemic inflammatory responses in a rat transient focal ischemia model. Neurosci Lett. 2016 10 28; 633:7-13. PMID: 27589890.
    Citations: 4     Fields:    Translation:AnimalsCells
  13. Guo Y, Zhou IY, Chan ST, Wang Y, Mandeville ET, Igarashi T, Lo EH, Ji X, Sun PZ. pH-sensitive MRI demarcates graded tissue acidification during acute stroke - pH specificity enhancement with magnetization transfer and relaxation-normalized amide proton transfer (APT) MRI. Neuroimage. 2016 Nov 01; 141:242-249. PMID: 27444569.
    Citations: 11     Fields:    Translation:Animals
  14. Shindo A, Maki T, Mandeville ET, Liang AC, Egawa N, Itoh K, Itoh N, Borlongan M, Holder JC, Chuang TT, McNeish JD, Tomimoto H, Lok J, Lo EH, Arai K. Astrocyte-Derived Pentraxin 3 Supports Blood-Brain Barrier Integrity Under Acute Phase of Stroke. Stroke. 2016 Apr; 47(4):1094-100. PMID: 26965847.
    Citations: 9     Fields:    Translation:AnimalsCells
  15. Liang AC, Mandeville ET, Maki T, Shindo A, Som AT, Egawa N, Itoh K, Chuang TT, McNeish JD, Holder JC, Lok J, Lo EH, Arai K. Effects of Aging on Neural Stem/Progenitor Cells and Oligodendrocyte Precursor Cells After Focal Cerebral Ischemia in Spontaneously Hypertensive Rats. Cell Transplant. 2016; 25(4):705-14. PMID: 26811151.
    Citations: 1     Fields:    Translation:AnimalsCells
  16. Lin H, Fang H, Wang J, Meng Q, Dai X, Wu S, Luo J, Pu D, Chen L, Minick D, Arai K, Mandeville ET, Lo E, Holder JC, Chuang TT, Zhao J. Discovery of a novel 2,3,11,11a-tetrahydro-1H-pyrazino[1,2-b]isoquinoline-1,4(6H)-dione series promoting neurogenesis of human neural progenitor cells. Bioorg Med Chem Lett. 2015 Sep 01; 25(17):3748-53. PMID: 26142946.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  17. Gagnon L, Sakadžic S, Lesage F, Mandeville ET, Fang Q, Yaseen MA, Boas DA. Multimodal reconstruction of microvascular-flow distributions using combined two-photon microscopy and Doppler optical coherence tomography. Neurophotonics. 2015 Jan; 2(1):015008. PMID: 26157987.
    Citations: 4     
  18. Gagnon L, Sakadžic S, Lesage F, Musacchia JJ, Lefebvre J, Fang Q, Yücel MA, Evans KC, Mandeville ET, Cohen-Adad J, Polimeni JR, Yaseen MA, Lo EH, Greve DN, Buxton RB, Dale AM, Devor A, Boas DA. Quantifying the microvascular origin of BOLD-fMRI from first principles with two-photon microscopy and an oxygen-sensitive nanoprobe. J Neurosci. 2015 Feb 25; 35(8):3663-75. PMID: 25716864.
    Citations: 28     Fields:    Translation:HumansAnimals
  19. Sakadžic S, Mandeville ET, Gagnon L, Musacchia JJ, Yaseen MA, Yucel MA, Lefebvre J, Lesage F, Dale AM, Eikermann-Haerter K, Ayata C, Srinivasan VJ, Lo EH, Devor A, Boas DA. Large arteriolar component of oxygen delivery implies a safe margin of oxygen supply to cerebral tissue. Nat Commun. 2014 Dec 08; 5:5734. PMID: 25483924.
    Citations: 33     Fields:    Translation:AnimalsCells
  20. Sun PZ, Wang Y, Mandeville E, Chan ST, Lo EH, Ji X. Validation of fast diffusion kurtosis MRI for imaging acute ischemia in a rodent model of stroke. NMR Biomed. 2014 Nov; 27(11):1413-8. PMID: 25208309.
    Citations: 13     Fields:    Translation:Animals
  21. Xing C, Wang X, Cheng C, Montaner J, Mandeville E, Leung W, van Leyen K, Lok J, Wang X, Lo EH. Neuronal production of lipocalin-2 as a help-me signal for glial activation. Stroke. 2014 Jul; 45(7):2085-92. PMID: 24916903.
    Citations: 15     Fields:    Translation:HumansAnimalsCells
  22. Wang X, Fan X, Yu Z, Liao Z, Zhao J, Mandeville E, Guo S, Lo EH, Wang X. Effects of tissue plasminogen activator and annexin A2 combination therapy on long-term neurological outcomes of rat focal embolic stroke. Stroke. 2014 Feb; 45(2):619-22. PMID: 24368559.
    Citations: 9     Fields:    Translation:Animals
  23. Esposito E, Mandeville ET, Lo EH. Lower doses of isoflurane treatment has no beneficial effects in a rat model of intracerebral hemorrhage. BMC Neurosci. 2013 Oct 20; 14:129. PMID: 24138708.
    Citations: 1     Fields:    Translation:Animals
  24. Miyamoto N, Maki T, Pham LD, Hayakawa K, Seo JH, Mandeville ET, Mandeville JB, Kim KW, Lo EH, Arai K. Oxidative stress interferes with white matter renewal after prolonged cerebral hypoperfusion in mice. Stroke. 2013 Dec; 44(12):3516-21. PMID: 24072001.
    Citations: 36     Fields:    Translation:AnimalsCells
  25. Li Q, Atochin D, Kashiwagi S, Earle J, Wang A, Mandeville E, Hayakawa K, d'Uscio LV, Lo EH, Katusic Z, Sessa W, Huang PL. Deficient eNOS phosphorylation is a mechanism for diabetic vascular dysfunction contributing to increased stroke size. Stroke. 2013 Nov; 44(11):3183-8. PMID: 23988642.
    Citations: 15     Fields:    Translation:AnimalsCells
  26. Esposito E, Mandeville ET, Hayakawa K, Singhal AB, Lo EH. Effects of normobaric oxygen on the progression of focal cerebral ischemia in rats. Exp Neurol. 2013 Nov; 249:33-8. PMID: 23958492.
    Citations: 8     Fields:    Translation:Animals
  27. Srinivasan VJ, Mandeville ET, Can A, Blasi F, Climov M, Daneshmand A, Lee JH, Yu E, Radhakrishnan H, Lo EH, Sakadžic S, Eikermann-Haerter K, Ayata C. Multiparametric, longitudinal optical coherence tomography imaging reveals acute injury and chronic recovery in experimental ischemic stroke. PLoS One. 2013; 8(8):e71478. PMID: 23940761.
    Citations: 18     Fields:    Translation:Animals
  28. Foerch C, Rosidi NL, Schlunk F, Lauer A, Cianchetti FA, Mandeville E, Arai K, Yigitkanli K, Fan X, Wang X, van Leyen K, Steinmetz H, Schaffer CB, Lo EH. Intravenous tPA therapy does not worsen acute intracerebral hemorrhage in mice. PLoS One. 2013; 8(2):e54203. PMID: 23408937.
    Citations: 3     Fields:    Translation:Animals
  29. Esipova TV, Ye X, Collins JE, Sakadžic S, Mandeville ET, Murray CB, Vinogradov SA. Dendritic upconverting nanoparticles enable in vivo multiphoton microscopy with low-power continuous wave sources. Proc Natl Acad Sci U S A. 2012 Dec 18; 109(51):20826-31. PMID: 23213211.
    Citations: 7     Fields:    Translation:AnimalsCells
  30. Yigitkanli K, Pekcec A, Karatas H, Pallast S, Mandeville E, Joshi N, Smirnova N, Gazaryan I, Ratan RR, Witztum JL, Montaner J, Holman TR, Lo EH, van Leyen K. Inhibition of 12/15-lipoxygenase as therapeutic strategy to treat stroke. Ann Neurol. 2013 Jan; 73(1):129-35. PMID: 23192915.
    Citations: 30     Fields:    Translation:HumansAnimals
  31. Goergen CJ, Radhakrishnan H, Sakadžic S, Mandeville ET, Lo EH, Sosnovik DE, Srinivasan VJ. Optical coherence tractography using intrinsic contrast. Opt Lett. 2012 Sep 15; 37(18):3882-4. PMID: 23041891.
    Citations: 14     Fields:    Translation:AnimalsCells
  32. Srinivasan VJ, Radhakrishnan H, Lo EH, Mandeville ET, Jiang JY, Barry S, Cable AE. OCT methods for capillary velocimetry. Biomed Opt Express. 2012 Mar 01; 3(3):612-29. PMID: 22435106.
    Citations: 31     
  33. Cheung JS, Wang E, Zhang X, Mandeville E, Lo EH, Sorensen AG, Sun PZ. Fast radio-frequency enforced steady state (FRESS) spin echo MRI for quantitative T2 mapping: minimizing the apparent repetition time (TR) dependence for fast T2 measurement. NMR Biomed. 2012 Feb; 25(2):189-94. PMID: 21755552.
    Citations: 9     Fields:    Translation:Animals
  34. Sakadžic S, Roussakis E, Yaseen MA, Mandeville ET, Srinivasan VJ, Arai K, Ruvinskaya S, Wu W, Devor A, Lo EH, Vinogradov SA, Boas DA. Cerebral blood oxygenation measurement based on oxygen-dependent quenching of phosphorescence. J Vis Exp. 2011 May 04; (51). PMID: 21587157.
    Citations: 4     Fields:    Translation:Animals
  35. Fujiwara N, Mandeville ET, Geng X, Luo Y, Arai K, Wang X, Ji X, Singhal AB, Lo EH. Effect of normobaric oxygen therapy in a rat model of intracerebral hemorrhage. Stroke. 2011 May; 42(5):1469-72. PMID: 21415401.
    Citations: 4     Fields:    Translation:Animals
  36. Sakadzic S, Roussakis E, Yaseen MA, Mandeville ET, Srinivasan VJ, Arai K, Ruvinskaya S, Devor A, Lo EH, Vinogradov SA, Boas DA. Two-photon high-resolution measurement of partial pressure of oxygen in cerebral vasculature and tissue. Nat Methods. 2010 Sep; 7(9):755-9. PMID: 20693997.
    Citations: 84     Fields:    Translation:Animals
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.