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profileAdrienne G. Randolph, M.D.

TitleProfessor of Anaesthesia
InstitutionBoston Children's Hospital
DepartmentAnaesthesia
AddressChildrens Hospital
Anesthesia/MICU -FA 108
300 Longwood Ave
Boston MA 02115
Phone617/355-7327
Fax617/734-3863
vCardDownload vCard (login for email)
Other Positions
TitleProfessor of Pediatrics
InstitutionBoston Children's Hospital
DepartmentPediatrics


Collapse Mentoring 
Collapse current student opportunities
Available: 01/26/16, Expires: 12/23/16

Using a dataset from a multicenter study, the student will verify clinical data and perform preliminary analyses on clinical, genetic and cytokine data to evaluate the factors influencing the immune response to influenza and other severe infections.


Collapse Research 
Collapse research activities and funding
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
Most Recent  |  List All
R01AI084011     (RANDOLPH, ADRIENNE G)Jun 11, 2010 - May 31, 2014
NIH/NIAID
Genetic Epidemiology of Life-Threatening Influenza in Children
Role: Principal Investigator
R56AI084011     (RANDOLPH, ADRIENNE G)Sep 17, 2009 - Jun 10, 2010
NIH/NIAID
Genetic Epidemiology of Life-Threatening Influenza Infection in Children
Role: Principal Investigator
K23HL004278     (RANDOLPH, ADRIENNE G)Apr 1, 2000 - Mar 31, 2006
NIH/NHLBI
GENETIC EPIDEMIOLOGY OF RSV BRONCHIOLITIS AND ASTHMA
Role: Principal Investigator
F32HS000106     (RANDOLPH, ADRIENNE G)Sep 1, 1995
AHRQ
COMPUTERIZED PROTOCOL FOR MECHANICAL VENTILATION
Role: Principal Investigator

Collapse Bibliographic 
Collapse selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
List All   |   Timeline
  1. Choong K, Duffett M, Cook DJ, Randolph AG. The Impact of Clinical Trials Conducted by Research Networks in Pediatric Critical Care. Pediatr Crit Care Med. 2016 Sep; 17(9):837-44. PMID: 27351267.
    View in: PubMed
  2. Tasker RC, Randolph AG. The authors reply. Pediatr Crit Care Med. 2016 Jun; 17(6):583-4. PMID: 27261660.
    View in: PubMed
  3. Lee J, Faraoni D, Lee S, Brown M, Odegard K, Randolph A, DiNardo JA, Yuki K. Incidence and risk factors for postoperative vomiting following atrial septal defect repair in children. Paediatr Anaesth. 2016 Jun; 26(6):644-8. PMID: 27091811.
    View in: PubMed
  4. Randolph AG, Agan AA, Flanagan RF, Meece JK, Fitzgerald JC, Loftis LL, Truemper EJ, Li S, Ferdinands JM. Optimizing Virus Identification in Critically Ill Children Suspected of Having an Acute Severe Viral Infection. Pediatr Crit Care Med. 2016 Apr; 17(4):279-86. PMID: 26895562.
    View in: PubMed
  5. Randolph AG. Pragmatic trials in critically ill children are CATCHing on. Lancet. 2016 Apr 23; 387(10029):1697-8. PMID: 26946924.
    View in: PubMed
  6. Zgleszewski SE, Graham DA, Hickey PR, Brustowicz RM, Odegard KC, Koka R, Seefelder C, Navedo AT, Randolph AG. Anesthesiologist- and System-Related Risk Factors for Risk-Adjusted Pediatric Anesthesia-Related Cardiac Arrest. Anesth Analg. 2016 Feb; 122(2):482-9. PMID: 26554463.
    View in: PubMed
  7. Tasker RC, Randolph AG. Severity-of-Illness Scoring in Pediatric Critical Care: Quo Vadis? Pediatr Crit Care Med. 2016 Jan; 17(1):83-5. PMID: 26731320.
    View in: PubMed
  8. Torgerson DG, Giri T, Druley TE, Zheng J, Huntsman S, Seibold MA, Young AL, Schweiger T, Yin-Declue H, Sajol GD, Schechtman KB, Hernandez RD, Randolph AG, Bacharier LB, Castro M. Pooled Sequencing of Candidate Genes Implicates Rare Variants in the Development of Asthma Following Severe RSV Bronchiolitis in Infancy. PLoS One. 2015; 10(11):e0142649. PMID: 26587832; PMCID: PMC4654486.
    View in: PubMed, PubMed Central
  9. Madden K, Feldman HA, Chun RF, Smith EM, Sullivan RM, Agan AA, Keisling SM, Panoskaltsis-Mortari A, Randolph AG. Critically Ill Children Have Low Vitamin D-Binding Protein, Influencing Bioavailability of Vitamin D. Ann Am Thorac Soc. 2015 Nov; 12(11):1654-61. PMID: 26356094.
    View in: PubMed
  10. Geva A, Tasker RC, Randolph AG. Therapeutic Hypothermia in Children. N Engl J Med. 2015 Sep 3; 373(10):979. PMID: 26332559.
    View in: PubMed
  11. Tasker RC, Randolph AG. Pediatric Pulseless Arrest With "Nonshockable" Rhythm: Does Faster Time to Epinephrine Improve Outcome? JAMA. 2015 Aug 25; 314(8):776-7. PMID: 26305646.
    View in: PubMed
  12. Yealy DM, Huang DT, Delaney A, Knight M, Randolph AG, Daniels R, Nutbeam T. Recognizing and managing sepsis: what needs to be done? BMC Med. 2015; 13:98. PMID: 25927426; PMCID: PMC4410741.
    View in: PubMed, PubMed Central
  13. Randolph AG. The tremendous burden of sepsis on China's youngest children. Pediatr Crit Care Med. 2014 Nov; 15(9):896-7. PMID: 25370055.
    View in: PubMed
  14. Higgerson RA, Olsho LE, Christie LM, Rehder K, Doksum T, Gedeit R, Giuliano JS, Brennan B, Wendlandt R, Randolph AG. Variability in IRBs regarding parental acceptance of passive consent. Pediatrics. 2014 Aug; 134(2):e496-503. PMID: 25002659.
    View in: PubMed
  15. Faustino EV, Hanson S, Spinella PC, Tucci M, O'Brien SH, Nunez AR, Yung M, Truemper E, Qin L, Li S, Marohn K, Randolph AG. A multinational study of thromboprophylaxis practice in critically ill children. Crit Care Med. 2014 May; 42(5):1232-40. PMID: 24351371; PMCID: PMC4293013.
    View in: PubMed, PubMed Central
  16. Randolph AG, Kornetsky S. More consistent site institutional review board (IRB) input-more consistent site IRB output. Crit Care Med. 2014 May; 42(5):1292-3. PMID: 24736342.
    View in: PubMed
  17. Ferdinands JM, Olsho LE, Agan AA, Bhat N, Sullivan RM, Hall M, Mourani PM, Thompson M, Randolph AG. Effectiveness of influenza vaccine against life-threatening RT-PCR-confirmed influenza illness in US children, 2010-2012. J Infect Dis. 2014 Sep 1; 210(5):674-83. PMID: 24676207.
    View in: PubMed
  18. Randolph AG, Yip WK, Falkenstein-Hagander K, Weiss ST, Janssen R, Keisling S, Bont L. Vitamin D-binding protein haplotype is associated with hospitalization for RSV bronchiolitis. Clin Exp Allergy. 2014 Feb; 44(2):231-7. PMID: 24447085.
    View in: PubMed
  19. Valentine SL, Lightdale JR, Tran CM, Jiang H, Sloan SR, Kleinman ME, Randolph AG. Assessment of hemoglobin threshold for packed RBC transfusion in a medical-surgical PICU. Pediatr Crit Care Med. 2014 Feb; 15(2):e89-94. PMID: 24335991.
    View in: PubMed
  20. Goldstein B, Randolph AG. The authors reply. Pediatr Crit Care Med. 2014 Feb; 15(2):183. PMID: 24492192.
    View in: PubMed
  21. Randolph AG. Rigorous scoping review of randomized trials in pediatric critical care highlights need for a rigorous rethink. Crit Care. 2013; 17(6):1024. PMID: 24359621; PMCID: PMC4056752.
    View in: PubMed, PubMed Central
  22. Randolph AG, McCulloh RJ. Pediatric sepsis: important considerations for diagnosing and managing severe infections in infants, children, and adolescents. Virulence. 2014 Jan 1; 5(1):179-89. PMID: 24225404; PMCID: PMC3916372.
    View in: PubMed, PubMed Central
  23. Carcillo JA, Randolph AG, Hazelzet JA, Dellinger RP. The authors reply. Crit Care Med. 2013 Oct; 41(10):e295. PMID: 24060797.
    View in: PubMed
  24. Santschi M, Randolph AG, Rimensberger PC, Jouvet P. Mechanical ventilation strategies in children with acute lung injury: a survey on stated practice pattern*. Pediatr Crit Care Med. 2013 Sep; 14(7):e332-7. PMID: 23842587.
    View in: PubMed
  25. Valentine S, Sapru A, Randolph A. The authors reply. Crit Care Med. 2013 May; 41(5):e49. PMID: 23591230.
    View in: PubMed
  26. Hall MW, Geyer SM, Guo CY, Panoskaltsis-Mortari A, Jouvet P, Ferdinands J, Shay DK, Nateri J, Greathouse K, Sullivan R, Tran T, Keisling S, Randolph AG. Innate immune function and mortality in critically ill children with influenza: a multicenter study. Crit Care Med. 2013 Jan; 41(1):224-36. PMID: 23222256; PMCID: PMC3705720.
    View in: PubMed, PubMed Central
  27. Thomas NJ, Guardia CG, Moya FR, Cheifetz IM, Markovitz B, Cruces P, Barton P, Segal R, Simmons P, Randolph AG. A pilot, randomized, controlled clinical trial of lucinactant, a peptide-containing synthetic surfactant, in infants with acute hypoxemic respiratory failure. Pediatr Crit Care Med. 2012 Nov; 13(6):646-53. PMID: 22791092.
    View in: PubMed
  28. Eriksson CO, Graham DA, Uyeki TM, Randolph AG. Risk factors for mechanical ventilation in U.S. children hospitalized with seasonal influenza and 2009 pandemic influenza A*. Pediatr Crit Care Med. 2012 Nov; 13(6):625-31. PMID: 22895006.
    View in: PubMed
  29. Valentine SL, Sapru A, Higgerson RA, Spinella PC, Flori HR, Graham DA, Brett M, Convery M, Christie LM, Karamessinis L, Randolph AG. Fluid balance in critically ill children with acute lung injury. Crit Care Med. 2012 Oct; 40(10):2883-9. PMID: 22824936; PMCID: PMC3455114.
    View in: PubMed, PubMed Central
  30. Madden K, Feldman HA, Smith EM, Gordon CM, Keisling SM, Sullivan RM, Hollis BW, Agan AA, Randolph AG. Vitamin D deficiency in critically ill children. Pediatrics. 2012 Sep; 130(3):421-8. PMID: 22869836; PMCID: PMC4074622.
    View in: PubMed, PubMed Central
  31. Rice TW, Rubinson L, Uyeki TM, Vaughn FL, John BB, Miller RR, Higgs E, Randolph AG, Smoot BE, Thompson BT. Critical illness from 2009 pandemic influenza A virus and bacterial coinfection in the United States. Crit Care Med. 2012 May; 40(5):1487-98. PMID: 22511131; PMCID: PMC3653183.
    View in: PubMed, PubMed Central
  32. Lightdale JR, Randolph AG, Tran CM, Jiang H, Colon A, Houlahan K, Billet A, Sloan S, Lehmann LE. Impact of a conservative red blood cell transfusion strategy in children undergoing hematopoietic stem cell transplantation. Biol Blood Marrow Transplant. 2012 May; 18(5):813-7. PMID: 22080050.
    View in: PubMed
  33. Randolph AG, Vaughn F, Sullivan R, Rubinson L, Thompson BT, Yoon G, Smoot E, Rice TW, Loftis LL, Helfaer M, Doctor A, Paden M, Flori H, Babbitt C, Graciano AL, Gedeit R, Sanders RC, Giuliano JS, Zimmerman J, Uyeki TM. Critically ill children during the 2009-2010 influenza pandemic in the United States. Pediatrics. 2011 Dec; 128(6):e1450-8. PMID: 22065262; PMCID: PMC3387899.
    View in: PubMed, PubMed Central
  34. Faustino EV, Patel S, Thiagarajan RR, Cook DJ, Northrup V, Randolph AG. Survey of pharmacologic thromboprophylaxis in critically ill children. Crit Care Med. 2011 Jul; 39(7):1773-8. PMID: 21423003; PMCID: PMC3118917.
    View in: PubMed, PubMed Central
  35. O'Grady NP, Alexander M, Burns LA, Dellinger EP, Garland J, Heard SO, Lipsett PA, Masur H, Mermel LA, Pearson ML, Raad II, Randolph AG, Rupp ME, Saint S. Summary of recommendations: Guidelines for the Prevention of Intravascular Catheter-related Infections. Clin Infect Dis. 2011 May; 52(9):1087-99. PMID: 21467014; PMCID: PMC3106267.
    View in: PubMed, PubMed Central
  36. O'Grady NP, Alexander M, Burns LA, Dellinger EP, Garland J, Heard SO, Lipsett PA, Masur H, Mermel LA, Pearson ML, Raad II, Randolph AG, Rupp ME, Saint S. Guidelines for the prevention of intravascular catheter-related infections. Am J Infect Control. 2011 May; 39(4 Suppl 1):S1-34. PMID: 21511081.
    View in: PubMed
  37. O'Grady NP, Alexander M, Burns LA, Dellinger EP, Garland J, Heard SO, Lipsett PA, Masur H, Mermel LA, Pearson ML, Raad II, Randolph AG, Rupp ME, Saint S. Guidelines for the prevention of intravascular catheter-related infections. Clin Infect Dis. 2011 May; 52(9):e162-93. PMID: 21460264; PMCID: PMC3106269.
    View in: PubMed, PubMed Central
  38. Massicotte MP, Randolph A, Bauman M. Central venous line thromboprophylaxis: transforming "experience-based care" into "evidence-based care". J Intensive Care Med. 2011 Sep-Oct; 26(5):341-2. PMID: 21345882.
    View in: PubMed
  39. Santschi M, Jouvet P, Leclerc F, Gauvin F, Newth CJ, Carroll CL, Flori H, Tasker RC, Rimensberger PC, Randolph AG. Acute lung injury in children: therapeutic practice and feasibility of international clinical trials. Pediatr Crit Care Med. 2010 Nov; 11(6):681-9. PMID: 20228688.
    View in: PubMed
  40. Wylie MC, Graham DA, Potter-Bynoe G, Kleinman ME, Randolph AG, Costello JM, Sandora TJ. Risk factors for central line-associated bloodstream infection in pediatric intensive care units. Infect Control Hosp Epidemiol. 2010 Oct; 31(10):1049-56. PMID: 20731595.
    View in: PubMed
  41. Ventre K, Randolph A. WITHDRAWN: Ribavirin for respiratory syncytial virus infection of the lower respiratory tract in infants and young children. Cochrane Database Syst Rev. 2010; (5):CD000181. PMID: 20464715.
    View in: PubMed
  42. Karam O, Tucci M, Bateman ST, Ducruet T, Spinella PC, Randolph AG, Lacroix J. Association between length of storage of red blood cell units and outcome of critically ill children: a prospective observational study. Crit Care. 2010; 14(2):R57. PMID: 20377853; PMCID: PMC2887178.
    View in: PubMed, PubMed Central
  43. Fowler RA, Webb SA, Rowan KM, Sprung CL, Thompson BT, Randolph AG, Jouvet P, Lapinsky S, Rubinson L, Rello J, Cobb JP, Rice TW, Uyeki T, Marshall JC. Early observational research and registries during the 2009-2010 influenza A pandemic. Crit Care Med. 2010 Apr; 38(4 Suppl):e120-32. PMID: 20101176; PMCID: PMC3705715.
    View in: PubMed, PubMed Central
  44. Khemani RG, Randolph A, Markovitz B. Steroids for post extubation stridor: pediatric evidence is still inconclusive. Intensive Care Med. 2010 Jul; 36(7):1276-7. PMID: 20237767.
    View in: PubMed
  45. Spragg RG, Bernard GR, Checkley W, Curtis JR, Gajic O, Guyatt G, Hall J, Israel E, Jain M, Needham DM, Randolph AG, Rubenfeld GD, Schoenfeld D, Thompson BT, Ware LB, Young D, Harabin AL. Beyond mortality: future clinical research in acute lung injury. Am J Respir Crit Care Med. 2010 May 15; 181(10):1121-7. PMID: 20224063; PMCID: PMC2874454.
    View in: PubMed, PubMed Central
  46. Herscu P, Hoover TA, Randolph AG. Clinical prediction rules: new opportunities for pharma. Drug Discov Today. 2009 Dec; 14(23-24):1143-9. PMID: 19853059.
    View in: PubMed
  47. Halpern SD, Randolph AG, Angus DC. No child left behind: Enrolling children and adults simultaneously in critical care randomized trials. Crit Care Med. 2009 Sep; 37(9):2638-41. PMID: 19602971; PMCID: PMC2903616.
    View in: PubMed, PubMed Central
  48. Randolph AG. Management of acute lung injury and acute respiratory distress syndrome in children. Crit Care Med. 2009 Aug; 37(8):2448-54. PMID: 19531940.
    View in: PubMed
  49. Khemani RG, Randolph A, Markovitz B. Corticosteroids for the prevention and treatment of post-extubation stridor in neonates, children and adults. Cochrane Database Syst Rev. 2009; (3):CD001000. PMID: 19588321.
    View in: PubMed
  50. Randolph AG. The unique challenges of enrolling patients into multiple clinical trials. Crit Care Med. 2009 Jan; 37(1 Suppl):S107-11. PMID: 19104209.
    View in: PubMed
  51. Calhoun AW, Guyatt GH, Cabana MD, Lu D, Turner DA, Valentine S, Randolph AG. Addressing the unit of analysis in medical care studies: a systematic review. Med Care. 2008 Jun; 46(6):635-43. PMID: 18520319.
    View in: PubMed
  52. Bateman ST, Lacroix J, Boven K, Forbes P, Barton R, Thomas NJ, Jacobs B, Markovitz B, Goldstein B, Hanson JH, Li HA, Randolph AG. Anemia, blood loss, and blood transfusions in North American children in the intensive care unit. Am J Respir Crit Care Med. 2008 Jul 1; 178(1):26-33. PMID: 18420962.
    View in: PubMed
  53. Markovitz BP, Randolph AG, Khemani RG. Corticosteroids for the prevention and treatment of post-extubation stridor in neonates, children and adults. Cochrane Database Syst Rev. 2008; (2):CD001000. PMID: 18425866.
    View in: PubMed
  54. Waisbren SE, Bowles H, Hasan T, Zou KH, Emans SJ, Goldberg C, Gould S, Levine D, Lieberman E, Loeken M, Longtine J, Nadelson C, Patenaude AF, Quinn D, Randolph AG, Solet JM, Ullrich N, Walensky R, Weitzman P, Christou H. Gender differences in research grant applications and funding outcomes for medical school faculty. J Womens Health (Larchmt). 2008 Mar; 17(2):207-14. PMID: 18321172.
    View in: PubMed
  55. Randolph AG, Ogawa S. The financial impact of underestimating personnel needs associated with implementing a computerized patient record in the intensive care unit. J Crit Care. 2007 Mar; 22(1):34-9. PMID: 17371743.
    View in: PubMed
  56. Ventre K, Randolph AG. Ribavirin for respiratory syncytial virus infection of the lower respiratory tract in infants and young children. Cochrane Database Syst Rev. 2007; (1):CD000181. PMID: 17253446.
    View in: PubMed
  57. Zhang Y, Silvers CT, Randolph AG. Real-time evaluation of patient monitoring algorithms for critical care at the bedside. Conf Proc IEEE Eng Med Biol Soc. 2007; 2007:2783-6. PMID: 18002572.
    View in: PubMed
  58. Duffett M, Choong K, Ng V, Randolph A, Cook DJ. Surfactant therapy for acute respiratory failure in children: a systematic review and meta-analysis. Crit Care. 2007; 11(3):R66. PMID: 17573963; PMCID: PMC2206432.
    View in: PubMed, PubMed Central
  59. Durall AL, Laussen PC, Randolph AG. Potential for donation after cardiac death in a children's hospital. Pediatrics. 2007 Jan; 119(1):e219-24. PMID: 17200246.
    View in: PubMed
  60. Randolph AG, Forbes PW, Gedeit RG, Arnold JH, Wetzel RC, Luckett PM, O'Neil ME, Venkataraman ST, Meert KL, Cheifetz IM, Cox PN, Hanson JH. Cumulative fluid intake minus output is not associated with ventilator weaning duration or extubation outcomes in children. Pediatr Crit Care Med. 2005 Nov; 6(6):642-7. PMID: 16276328.
    View in: PubMed
  61. Randolph AG, Lange C, Silverman EK, Lazarus R, Weiss ST. Extended haplotype in the tumor necrosis factor gene cluster is associated with asthma and asthma-related phenotypes. Am J Respir Crit Care Med. 2005 Sep 15; 172(6):687-92. PMID: 15976383; PMCID: PMC2718550.
    View in: PubMed, PubMed Central
  62. Dahmer MK, Randolph A, Vitali S, Quasney MW. Genetic polymorphisms in sepsis. Pediatr Crit Care Med. 2005 May; 6(3 Suppl):S61-73. PMID: 15857562.
    View in: PubMed
  63. Vitali SH, Randolph AG. Assessing the quality of case-control association studies on the genetic basis of sepsis. Pediatr Crit Care Med. 2005 May; 6(3 Suppl):S74-7. PMID: 15857563; PMCID: PMC3705716.
    View in: PubMed, PubMed Central
  64. Randolph AG, Brun-Buisson C, Goldmann D. Identification of central venous catheter-related infections in infants and children. Pediatr Crit Care Med. 2005 May; 6(3 Suppl):S19-24. PMID: 15857552.
    View in: PubMed
  65. Goldstein B, Giroir B, Randolph A. International pediatric sepsis consensus conference: definitions for sepsis and organ dysfunction in pediatrics. Pediatr Crit Care Med. 2005 Jan; 6(1):2-8. PMID: 15636651.
    View in: PubMed
  66. Randolph AG, Reder L, Englund JA. Risk of bacterial infection in previously healthy respiratory syncytial virus-infected young children admitted to the intensive care unit. Pediatr Infect Dis J. 2004 Nov; 23(11):990-4. PMID: 15545852; PMCID: PMC3705636.
    View in: PubMed, PubMed Central
  67. Ventre K, Randolph A. Ribavirin for respiratory syncytial virus infection of the lower respiratory tract in infants and young children. Cochrane Database Syst Rev. 2004; (4):CD000181. PMID: 15494991.
    View in: PubMed
  68. Al-Majed SI, Thompson JE, Watson KF, Randolph AG. Effect of lung compliance and endotracheal tube leakage on measurement of tidal volume. Crit Care. 2004 Dec; 8(6):R398-402. PMID: 15566583; PMCID: PMC1065056.
    View in: PubMed, PubMed Central
  69. Davison C, Ventre KM, Luchetti M, Randolph AG. Efficacy of interventions for bronchiolitis in critically ill infants: a systematic review and meta-analysis. Pediatr Crit Care Med. 2004 Sep; 5(5):482-9. PMID: 15329166; PMCID: PMC3867796.
    View in: PubMed, PubMed Central
  70. Randolph AG, Lange C, Silverman EK, Lazarus R, Silverman ES, Raby B, Brown A, Ozonoff A, Richter B, Weiss ST. The IL12B gene is associated with asthma. Am J Hum Genet. 2004 Oct; 75(4):709-15. PMID: 15322986; PMCID: PMC1182059.
    View in: PubMed, PubMed Central
  71. Randolph AG, Gonzales CA, Cortellini L, Yeh TS. Growth of pediatric intensive care units in the United States from 1995 to 2001. J Pediatr. 2004 Jun; 144(6):792-8. PMID: 15192628.
    View in: PubMed
  72. Venkataraman S, Randolph A, Hanson J, Forbes P, Cheifetz I, Gedeit R, Luckett P. All roses are flowers, but not all flowers are roses. Am J Respir Crit Care Med. 2004 Apr 15; 169(8):969. PMID: 15072986.
    View in: PubMed
  73. Randolph AG. How are children mechanically ventilated in pediatric intensive care units? Intensive Care Med. 2004 May; 30(5):746-7. PMID: 14991084.
    View in: PubMed
  74. Lyon H, Lange C, Lake S, Silverman EK, Randolph AG, Kwiatkowski D, Raby BA, Lazarus R, Weiland KM, Laird N, Weiss ST. IL10 gene polymorphisms are associated with asthma phenotypes in children. Genet Epidemiol. 2004 Feb; 26(2):155-65. PMID: 14748015; PMCID: PMC3705717.
    View in: PubMed, PubMed Central
  75. Lyon H, Lange C, Lake S, Silverman EK, Randolph AG, Kwiatkowski D, Raby BA, Lazarus R, Weiland KM, Laird N, Weiss ST. IL-10 gene polymorphisms are associated with asthma phenotypes in children. Genetic Edidemiol. 2004; 26:155-65.
  76. Randolph AG. How are children mechanically ventilated in PICUs?. Intensive Care Med. 2004; 30:746.
  77. Goldstein B, Giroir B, Randolph A. . International Pediatric Sepsis Consensus Conference: Definitions for sepsis and organ dysfunction in pediatrics. Pediatr Crit Care Med, in press. 2004.
  78. Al-Majed SI, Thompson JE, Watson KF, Randolph AG. Effect of endotracheal tube leak and lung compliance on measurement of tidal volume in children. Citical Care. 2004; 8:398-402.
  79. Randolph AG. A practical approach to evidence-based medicine: lessons learned from developing ventilator management protocols. Crit Care Clin. 2003 Jul; 19(3):515-27. PMID: 12848318.
    View in: PubMed
  80. Randolph AG. Central line complications in an infant. AHRQ Web M&M Spotlight Commentary. 2003; (http://webmm.ahrq.gov).
  81. Nicholson CE, Gans BM, Chang AC, Pollack MM, Blackman J, Giroir BP, Wilson D, Zimmerman JJ, Whyte J, Dalton HJ, Carcillo JA, Randolph AG, Kochanek PM. Pediatric critical care medicine: planning for our research future. Pediatr Crit Care Med. 2003 Apr; 4(2):196-202. PMID: 12749652.
    View in: PubMed
  82. Randolph AG, Meert KL, O'Neil ME, Hanson JH, Luckett PM, Arnold JH, Gedeit RG, Cox PN, Roberts JS, Venkataraman ST, Forbes PW, Cheifetz IM. The feasibility of conducting clinical trials in infants and children with acute respiratory failure. Am J Respir Crit Care Med. 2003 May 15; 167(10):1334-40. PMID: 12615617.
    View in: PubMed
  83. Randolph AG, Lange C, Silverman EK, Weiss ST. Association between IL12B polymorphisms in the CAMP study. Amer J Resp Crit Care Med. 2003; 167:A750.
  84. Randolph AG, Meert KL, O’Neil ME, Hanson JH, Luckett PM, Arnold JH, Gedeit RG, Cox PN, Roberts JS, Venkataraman ST, Forbes PW, Cheifetz IM. for the Pediatric Acute Lung Injury and Sepsis Investigator’s Network. The feasibility of conducting clinical trials in infants and children with acute respiratory failure. Am J Resp Crit Care Med. 2003; 167:1334-40.
  85. Cooper M, Randolph AG. Preventing central venous catheter-related complications. In Evidence-Based Resource in Anaesthesia and Analgesia, Editor: Martin R. Tramer. BMJ Books, London UK. 2003; 126-139.
  86. O'Grady NP, Alexander M, Dellinger EP, Gerberding JL, Heard SO, Maki DG, Masur H, McCormick RD, Mermel LA, Pearson ML, Raad II, Randolph A, Weinstein RA. Guidelines for the prevention of intravascular catheter-related infections. Clin Infect Dis. 2002 Dec 1; 35(11):1281-307. PMID: 12439791.
    View in: PubMed
  87. O'Grady NP, Alexander M, Dellinger EP, Gerberding JL, Heard SO, Maki DG, Masur H, McCormick RD, Mermel LA, Pearson ML, Raad II, Randolph A, Weinstein RA. Guidelines for the prevention of intravascular catheter-related infections. Infect Control Hosp Epidemiol. 2002 Dec; 23(12):759-69. PMID: 12517020.
    View in: PubMed
  88. O'grady NP, Alexander M, Dellinger EP, Gerberding JL, Heard SO, Maki DG, Masur H, McCormick RD, Mermel LA, Pearson ML, Raad II, Randolph A, Weinstein RA. Guidelines for the prevention of intravascular catheter-related infections. Am J Infect Control. 2002 Dec; 30(8):476-89. PMID: 12461511.
    View in: PubMed
  89. Randolph AG, Wypij D, Venkataraman ST, Hanson JH, Gedeit RG, Meert KL, Luckett PM, Forbes P, Lilley M, Thompson J, Cheifetz IM, Hibberd P, Wetzel R, Cox PN, Arnold JH. Effect of mechanical ventilator weaning protocols on respiratory outcomes in infants and children: a randomized controlled trial. JAMA. 2002 Nov 27; 288(20):2561-8. PMID: 12444863.
    View in: PubMed
  90. O'Grady NP, Alexander M, Dellinger EP, Gerberding JL, Heard SO, Maki DG, Masur H, McCormick RD, Mermel LA, Pearson ML, Raad II, Randolph A, Weinstein RA. Guidelines for the prevention of intravascular catheter-related infections. The Hospital Infection Control Practices Advisory Committee, Center for Disease Control and Prevention, U.S. Pediatrics. 2002 Nov; 110(5):e51. PMID: 12415057.
    View in: PubMed
  91. O'Grady NP, Alexander M, Dellinger EP, Gerberding JL, Heard SO, Maki DG, Masur H, McCormick RD, Mermel LA, Pearson ML, Raad II, Randolph A, Weinstein RA. Guidelines for the prevention of intravascular catheter-related infections. Centers for Disease Control and Prevention. MMWR Recomm Rep. 2002 Aug 9; 51(RR-10):1-29. PMID: 12233868.
    View in: PubMed
  92. Randolph AG. What underlies race and sex differences in acute respiratory distress syndrome-associated mortality? Crit Care Med. 2002 Aug; 30(8):1907-9. PMID: 12163816.
    View in: PubMed
  93. Markovitz BP, Randolph AG. Corticosteroids for the prevention of reintubation and postextubation stridor in pediatric patients: A meta-analysis. Pediatr Crit Care Med. 2002 Jul; 3(3):223-226. PMID: 12780960.
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  94. Randolph AG. Mining for the genetic determinants of septic shock: when is it really gold? Crit Care Med. 2002 May; 30(5):1161-3. PMID: 12006822.
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  95. Randolph AG, Pronovost P. Reorganizing the delivery of intensive care could improve efficiency and save lives. J Eval Clin Pract. 2002 Feb; 8(1):1-8. PMID: 11882096.
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  96. Randolph AG, Pronovost P. Reorganising the delivery of intensive care could improve efficiency and save lives. J Eval Clin Practice. 2002; 8:1-8.
  97. Randolph AG, Lacroix J. Randomized clinical trials in pediatric critical care: Rarely done but desperately needed. Pediatr Crit Care Med. 2002 Apr; 3(2):102-106. PMID: 12780976.
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  98. Al-Majed S, Thompson JE, Watson KF, Palmer L, Randolph AG. Measured tidal volume is influenced by lung compliance. Amer J Resp Crit Care Med. 2002; 165:A376.
  99. Randolph AG. What underlies racial and gender differences in ARDS-associated mortality?. Crit Care Med. 2002; 3:1907-1909.
  100. Randolph AG, Graham R. Measuring the health status of pediatric intensive care unit survivors. 2002 Yearbook of Intensive Care and Emergency Medicine, Ed. J.L. Vincent, in press. 2002.
  101. O'Grady NP, Alexander M, Dellinger EP, Gerberding JL, Heard SO, Maki DG, Masur H, McCormick RD, Mermel LA, Pearson ML, Raad II, Randolph A, Weinstein RA. . Guidelines for the prevention of intravascular catheter-related infections. Pediatrics. 2002; 110:e51.
  102. Markovitz B, Randolph AG. Corticosteroids for the prevention of reintubation and post-extubation stridor in pediatric patients: a meta-analysis. Pediatr Crit Care Med. 2002; 3:223-226.
  103. Randolph AG, Venkataraman ST, Gedeit R, Hanson JH, Meert K, Luckett PM, Arnold J, Lilley M, Thompson J, Cheifetz IM, Wetzel R, Cox P, Roberts J. for the Pediatric Acute Lung Injury and Sepsis Investigator’s Network. Weaning critically ill children from ventilator support: a randomized trial comparing two protocols to standard care. Amer J Resp Crit Care Med. 2002; 165:A156.
  104. Randolph AG. Upper gastrointestinal bleeding in the pediatric intensive care unit: clinically important but questionably preventable. Pediatr Crit Care Med. 2001 Oct; 2(4):349-50. PMID: 12813241.
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  105. Randolph AG. Randomized clinical trials in pediatric critical care. 2001 Yearbook of Intensive Care and Emergency Medicine, Ed. J.-L. Vincent. 2001; 676-684.
  106. Davison C, Luchetti M, Randolph AG. Systematic review of treatments for critically ill infants with bronchiolitis. Crit Care Med. 2001; 29:A144.
  107. Randolph A, Haynes B, Wyatt J, Cook D, Guyatt G. Therapy and validity: Computer Decision Support Systems. In: Guyatt G, Rennie D, editors. Users’ guides to the medical literature. Chicago: AMA Press. 2001; 291-308.
  108. Randolph AG, Venkataraman S, Hanson J, Luckett P, Gedeit R, Meert K, Wetzel R, Cheifetz I, Cox P, Roberts J, Lilley M, Thompson J, Arnold J. Evaluation of a pediatric extubation readiness test. Crit Care Med. 2001; 29:A142.
  109. Randolph A, Bucher H, Richardson WS, Wells G, Tugwell P, Guyatt G. Prognosis. In: Guyatt G, Rennie D, editors. Users’ guides to the medical literature. Chicago: AMA Press. 2001; 141-54.
  110. Al-Majed SI, Thompson JE, Watson KF, Palmer L, Randolph AG. Tidal volume (VT) is most accurately measured at the endotracheal tube when lung compliance is poor. Crit Care Med. 2001; 29:A69.
  111. Markovitz BP, Randolph AG. Corticosteroids for the prevention and treatment of post-extubation stridor in neonates, children and adults. Cochrane Database Syst Rev. 2000; (2):CD001000. PMID: 10796576.
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  112. Randolph AG, Wang EE. Ribavirin for respiratory syncytial virus infection of the lower respiratory tract. Cochrane Database Syst Rev. 2000; (2):CD000181. PMID: 10796503.
    View in: PubMed
  113. Randolph AG, Haynes RB, Wyatt JC, Cook DJ, Guyatt GH. Users' Guides to the Medical Literature: XVIII. How to use an article evaluating the clinical impact of a computer-based clinical decision support system. JAMA. 1999 Jul 7; 282(1):67-74. PMID: 10404914.
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  114. Randolph AG. Reorganizing the delivery of intensive care may improve patient outcomes. JAMA. 1999 Apr 14; 281(14):1330-1. PMID: 10208151.
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  115. Randolph AG, Zollo MB, Egger MJ, Guyatt GH, Nelson RM, Stidham GL. Variability in physician opinion on limiting pediatric life support. Pediatrics. 1999 Apr; 103(4):e46. PMID: 10103338.
    View in: PubMed
  116. Truog RD, Robinson W, Randolph A, Morris A. Is informed consent always necessary for randomized, controlled trials? . N Engl J Med. 1999 Mar 11; 340(10):804-7. PMID: 10072420.
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  117. Bateman S, Randolph AG. Efficacy of continuous vs. intermittent furosemide. Crit Care Med. 1999; 27:A59.
  118. Randolph AG, Cook DJ. Antiseptic hub connectors reduce central venous catheter-related sepsis. Crit Care Med. 1999; 27:A141.
  119. Randolph AG, DeJonghe B, Merrer J, Cook DJ. Single versus multilumen central venous catheters: a critical appraisal of the infection risk. Crit Care Med. 1999; 27:A141.
  120. Markovitz B, Randolph AG. The Pediatric Critical Care Evidence-Based Internet Journal Club: interim evaluation. Crit Care Med. 1999; 27:A99.
  121. Ackerman KG, Creery D, Randolph AG. Outcome of out-of-hospital pediatric pulseless arrest. Crit Care Med. 1999; 27:A65.
  122. Randolph AG. Weaning from mechanical ventilation. New Horiz. 1999; 7:374-385.
  123. Randolph AG, Clemmer TP, East TD, Kinder AT, Orme JF, Wallace CJ, Morris AH. Evaluation of compliance with a computerized protocol: weaning from mechanical ventilator support using pressure support. Comput Methods Programs Biomed. 1998 Nov; 57(3):201-15. PMID: 9822857.
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  124. Randolph AG, Guyatt GH, Calvin JE, Doig G, Richardson WS. Understanding articles describing clinical prediction tools. Evidence Based Medicine in Critical Care Group. Crit Care Med. 1998 Sep; 26(9):1603-12. PMID: 9751601.
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  125. Randolph AG, Cook DJ, Gonzales CA, Brun-Buisson C. Tunneling short-term central venous catheters to prevent catheter-related infection: a meta-analysis of randomized, controlled trials. Crit Care Med. 1998 Aug; 26(8):1452-7. PMID: 9710109.
    View in: PubMed
  126. Randolph AG. An evidence-based approach to central venous catheter management to prevent catheter-related infection in critically ill patients. Crit Care Clin. 1998 Jul; 14(3):411-21. PMID: 9700439.
    View in: PubMed
  127. Randolph AG, Guyatt GH, Richardson WS. Prognosis in the intensive care unit: finding accurate and useful estimates for counseling patients. Crit Care Med. 1998 Apr; 26(4):767-72. PMID: 9559618.
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  128. Randolph AG, Guyatt GH, Carlet J. Understanding articles comparing outcomes among intensive care units to rate quality of care. Evidence Based Medicine in Critical Care Group. Crit Care Med. 1998 Apr; 26(4):773-81. PMID: 9559619.
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  129. Randolph AG, Cook DJ, Gonzales CA, Andrew M. Benefit of heparin in peripheral venous and arterial catheters: systematic review and meta-analysis of randomised controlled trials. BMJ. 1998 Mar 28; 316(7136):969-75. PMID: 9550955; PMCID: PMC28499.
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  130. Randolph AG, Guyatt GH, Calvin JE, Doig G. Understanding articles describing clinical prediction tools. Crit Care Med. 1998; 26:1603-12.
  131. McGinn T, Randolph A, Richardson S, Sackett D. Clinical Prediction Guidelines. Evidence Based Medicine. 1998; 3:5-6.
  132. Randolph AG, Cook DJ, Gonzales CA, Andrew M. Benefit of heparin in central venous and pulmonary artery catheters: a meta-analysis of randomized controlled trials. Chest. 1998 Jan; 113(1):165-71. PMID: 9440585.
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  133. Randolph AG, Zollo MB, Egger JM, Guyatt GH, Nelson RM, Stidham GL. Variability in physician opinion on limiting pediatric life support. URL http://www.pediatrics.org/cgi/content/full/103/4/e46. Pediatrics. 1998; 103:807.
  134. McGinn T, Randolph A, Richardson S, Sackett D. Clinical prediction guides. ACP J Club. 1998 Jan-Feb; 128(1):A14-5. PMID: 9442199.
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  135. Randolph AG. An evidence based approach to central venous catheter management. Crit Care Clinics. 1998; 14:411-21.
  136. Randolph AG, Cook DJ, Gonzales CA, Brun-Buisson C. Tunneling of central venous catheters: a meta-analysis of randomized controlled trials. Crit Care Med. 1998; 26:1452-7.
  137. Randolph AG, Goldmann DA. Cost-effectiveness of 10 strategies for managing suspected central venous catheter-related infections. Pediatr Res. 1998; 43:155A.
  138. Azzam MA, Randolph AG, Butt W. Positive predictive value of bilateral absence of somatosensory evoked potentials in severe traumatic brain injury. Pediatr Res. 1998; 43:33A.
  139. Randolph AG, Kane J. Potential for meeting clinician information requirements in an intensive care unit (ICU) via the web. Proc AMIA Symp. 1998; 96-100. PMID: 9929189; PMCID: PMC2232111.
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  140. Cook D, Randolph A, Kernerman P, Cupido C, King D, Soukup C, Brun-Buisson C. Central venous catheter replacement strategies: a systematic review of the literature. Crit Care Med. 1997 Aug; 25(8):1417-24. PMID: 9267959.
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  141. Randolph AG, Zollo MB, Wigton RS, Yeh TS. Factors explaining variability among caregivers in the intent to restrict life-support interventions in a pediatric intensive care unit. Crit Care Med. 1997 Mar; 25(3):435-9. PMID: 9118659.
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  142. Randolph AG. Paediatric index of mortality (PIM): do we need another paediatric mortality prediction score? Intensive Care Med. 1997 Feb; 23(2):141-2. PMID: 9068997.
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  143. Randolph AG. Critical appraisal of “Dexamethasone in the prevention of postextubation stridor in children” by DW Tellez et al. PedsCCM Evidence-Based Journal Club. 1997; http://PedsCCM.wustl.edu/EBJ/T.
  144. Randolph AG. Critical appraisal of “Outcome of out-of-hospital cardiac or respiratory arrest in children” by MB Schindler et al. PedsCCM Evidence-Based Journal Club. 1997; http://PedsCCM.wustl.edu/EBJ/P.
  145. Randolph AG, Markovitz B. Resources for applying evidence based medicine in the Pediatric Intensive Care Unit (PICU). J Int Care Med. 1997; 12:316-320.
  146. Randolph AG. Critical appraisal of “Dexamethasone for the prevention of postextubation airway obstruction: a prospective, randomized, double-blind, placebo-controlled trial” by O. Anene et al. PedsCCM Evidence-Based Journal Club. 1997; http://PedsCCM.wustl.edu/EBJ/T.
  147. Randolph AG. Critical appraisal of “Diagnosis and treatment of ventilator-associated pneumonia—impact on survival” by TR Sterling et al. PedsCCM Evidence-Based Journal Club. 1997; http://PedsCCM.wustl.edu/EBJ/D.
  148. Randolph AG. The critical care database of randomized controlled trials: A resource to facilitate evidence-based practice in the intensive care unit. Critical Care. 1997; 0:25-8.
  149. Cook DJ, Randolph AG, Kernerman P, Cupido C, Soukup M, King D, Brun-Buisson C. Central venous catheter exchange strategies: a meta-analysis of randomized controlled trials. Crit Care Med. 1997; 25:1417-24.
  150. Gonzalez CA, Randolph AG, Perloff WH, Yeh TS. Pediatric intensive care units in 1995;numbers, characteristics, and distribution. Pediatrics. 1997; 100(3):449.
  151. Randolph AG. Critical appraisal of “UK collaborative randomized trial of neonatal extracorporeal membrane oxygenation” by the UK Collaborative ECMO Trial Group. PedsCCM Evidence-Based Journal Club. 1997; http://PedsCCM.wustl.edu/EBJ/T.
  152. Randolph AG, Cook DJ, Gonzales CA, Pribble CG. Ultrasound guidance for placement of central venous catheters: a meta-analysis of the literature. Crit Care Med. 1996 Dec; 24(12):2053-8. PMID: 8968276.
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  153. Randolph AG, Hartshorn RM, Washington AE. Acyclovir prophylaxis in late pregnancy to prevent neonatal herpes: a cost-effectiveness analysis. Obstet Gynecol. 1996 Oct; 88(4 Pt 1):603-10. PMID: 8841227.
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  154. Randolph AG, Wang EE. Ribavirin for respiratory syncytial virus lower respiratory tract infection. A systematic overview. Arch Pediatr Adolesc Med. 1996 Sep; 150(9):942-7. PMID: 8790125.
    View in: PubMed
  155. Randolph AG. A computerized protocol for weaning patients from mechanical ventilation using the pressure support mode. 1996.
  156. Randolph AG, Wang EEL. Ribavirin for respiratory syncytial virus lower respiratory tract infection: a systematic overview. Arch Pediatr Adol Med. 1996; 150:942-7.
  157. Sailors RM, East TD, Wallace CJ, Carlson DA, Franklin MA, Heermann LK, Kinder AT, Bradshaw RL, Randolph AG, Morris AH. Testing and validation of computerized decision support systems. Proc AMIA Annu Fall Symp. 1996; 234-8. PMID: 8947663; PMCID: PMC2233208.
    View in: PubMed, PubMed Central
  158. Randolph AG. Learning airway management skills: guidelines for pediatrics. Arch Pediatr Adolesc Med. 1994 Feb; 148(2):227-8. PMID: 8118549.
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  159. Randolph AG. Learning airway management skills: guidelines for pediatrics. Arch Pediatr Adoles Med. 1994; 148:227-8.
  160. Randolph AG, Washington AE, Prober CG. Cesarean delivery for women presenting with genital herpes lesions. Efficacy, risks, and costs. JAMA. 1993 Jul 7; 270(1):77-82. PMID: 8510301.
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  161. Randolph AG, Washington AE. Screening for Chlamydia trachomatis in adolescent males: a cost-based decision analysis. Am J Public Health. 1990 May; 80(5):545-50. PMID: 2109544; PMCID: PMC1404639.
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  162. Randolph AG, Washington AE. Screening for Chlamydia trachomatis in adolescent males: cost and benefits of the leukocyte esterase urine dipstick test. Am J Pub Health. 1990; 80:545-50.
  163. Randolph AG. Cerebral hemisphere involvement in recognizing nonsense words, and in matching picture patterns and facial emotions. 1985.
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