Harvard Catalyst Profiles

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Adrienne G. Randolph, M.D.

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Other Positions
Title
Institution
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Research
research activities and funding
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
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  1. R01AI154470 (RANDOLPH, ADRIENNE G) Sep 18, 2020 - Aug 31, 2024
    NIH
    Immunobiology of Influenza Virus-related Critical Illness in Young Hosts
    Role: Principal Investigator
  2. R21HD095228 (RANDOLPH, ADRIENNE G) Aug 17, 2018 - Jul 31, 2021
    NIH
    Genes Associated with MODS in Children with Severe Acute Respiratory Infections
    Role: Principal Investigator
  3. R01AI084011 (RANDOLPH, ADRIENNE G) Jun 11, 2010 - May 31, 2016
    NIH
    Genetic Epidemiology of Life-Threatening Influenza in Children
    Role: Principal Investigator
  4. R56AI084011 (RANDOLPH, ADRIENNE G) Sep 17, 2009 - Jun 10, 2010
    NIH
    Genetic Epidemiology of Life-Threatening Influenza Infection in Children
    Role: Principal Investigator
  5. K23HL004278 (RANDOLPH, ADRIENNE G) Apr 1, 2000 - Mar 31, 2006
    NIH
    GENETIC EPIDEMIOLOGY OF RSV BRONCHIOLITIS AND ASTHMA
    Role: Principal Investigator

Bibliographic
selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Emeriaud G, López-Fernández YM, Iyer NP, Bembea MM, Agulnik A, Barbaro RP, Baudin F, Bhalla A, Brunow de Carvalho W, Carroll CL, Cheifetz IM, Chisti MJ, Cruces P, Curley MAQ, Dahmer MK, Dalton HJ, Erickson SJ, Essouri S, Fernández A, Flori HR, Grunwell JR, Jouvet P, Killien EY, Kneyber MCJ, Kudchadkar SR, Korang SK, Lee JH, Macrae DJ, Maddux A, Modesto I Alapont V, Morrow BM, Nadkarni VM, Napolitano N, Newth CJL, Pons-Odena M, Quasney MW, Rajapreyar P, Rambaud J, Randolph AG, Rimensberger P, Rowan CM, Sanchez-Pinto LN, Sapru A, Sauthier M, Shein SL, Smith LS, Steffen K, Takeuchi M, Thomas NJ, Tse SM, Valentine S, Ward S, Watson RS, Yehya N, Zimmerman JJ, Khemani RG. Executive Summary of the Second International Guidelines for the Diagnosis and Management of Pediatric Acute Respiratory Distress Syndrome (PALICC-2). Pediatr Crit Care Med. 2023 Feb 01; 24(2):143-168. PMID: 36661420; PMCID: PMC9848214.
    Citations:    Fields:    
  2. Rowan CM, Randolph AG, Iyer NP, Korang SK, Kneyber MCJ. Pulmonary Specific Ancillary Treatment for Pediatric Acute Respiratory Distress Syndrome: From the Second Pediatric Acute Lung Injury Consensus Conference. Pediatr Crit Care Med. 2023 Feb 01; 24(Supplement 1 2S):S99-S111. PMID: 36661439.
    Citations:    Fields:    
  3. Sahajpal NS, Hastie AR, Schieck M, Mondal AK, Felde M, van der Made CI, Chou JS, Randolph AG, Illig T, Zody MC, Brownstein CA, Beggs AH, Hoischen A, Chaubey A, Kolhe R. Genetic Predisposition to Neurological Complications in Patients with COVID-19. Biomolecules. 2023 Jan 09; 13(1). PMID: 36671517; PMCID: PMC9855758.
    Citations:    Fields:    
  4. Yonker LM, Swank Z, Bartsch YC, Burns MD, Kane A, Boribong BP, Davis JP, Loiselle M, Novak T, Senussi Y, Cheng CA, Burgess E, Edlow AG, Chou J, Dionne A, Balaguru D, Lahoud-Rahme M, Arditi M, Julg B, Randolph AG, Alter G, Fasano A, Walt DR. Circulating Spike Protein Detected in Post-COVID-19 mRNA Vaccine Myocarditis. Circulation. 2023 Jan 04. PMID: 36597886.
    Citations:    Fields:    
  5. Ledderose C, Valsami EA, Newhams M, Elevado MJ, Novak T, Randolph AG, Junger WG. ATP breakdown in plasma of children limits the antimicrobial effectiveness of their neutrophils. Purinergic Signal. 2023 Jan 04. PMID: 36596963.
    Citations:    Fields:    
  6. Benamar M, Chen Q, Chou J, Julé AM, Boudra R, Contini P, Crestani E, Lai PS, Wang M, Fong J, Rockwitz S, Lee P, Chan TMF, Altun EZ, Kepenekli E, Karakoc-Aydiner E, Ozen A, Boran P, Aygun F, Onal P, Sakalli AAK, Cokugras H, Gelmez MY, Oktelik FB, Cetin EA, Zhong Y, Taylor ML, Irby K, Halasa NB, Mack EH, Signa S, Prigione I, Gattorno M, Cotugno N, Amodio D, Geha RS, Son MB, Newburger J, Agrawal PB, Volpi S, Palma P, Kiykim A, Randolph AG, Deniz G, Baris S, De Palma R, Schmitz-Abe K, Charbonnier LM, Henderson LA, Chatila TA. The Notch1/CD22 signaling axis disrupts Treg function in SARS-CoV-2-associated multisystem inflammatory syndrome in children. J Clin Invest. 2023 01 03; 133(1). PMID: 36282598; PMCID: PMC9797337.
    Citations: 1     Fields:    Translation:HumansCells
  7. LaRovere KL, Poussaint TY, Young CC, Newhams MM, Kucukak S, Irby K, Kong M, Schwartz SP, Walker TC, Bembea MM, Wellnitz K, Havlin KM, Cvijanovich NZ, Hall MW, Fitzgerald JC, Schuster JE, Hobbs CV, Halasa NB, Singh AR, Mack EH, Bradford TT, Gertz SJ, Schwarz AJ, Typpo KV, Loftis LL, Giuliano JS, Horwitz SM, Biagas KV, Clouser KN, Rowan CM, Maddux AB, Soma VL, Babbitt CJ, Aguiar CL, Kolmar AR, Heidemann SM, Harvey H, Zambrano LD, Campbell AP, Randolph AG. Changes in Distribution of Severe Neurologic Involvement in US Pediatric Inpatients With COVID-19 or Multisystem Inflammatory Syndrome in Children in 2021 vs 2020. JAMA Neurol. 2023 Jan 01; 80(1):91-98. PMID: 36342679; PMCID: PMC9641594.
    Citations:    Fields:    Translation:HumansCellsPHPublic Health
  8. Hahn G, Lee S, Prokopenko D, Abraham J, Novak T, Hecker J, Cho M, Khurana S, Baden LR, Randolph AG, Weiss ST, Lange C. Unsupervised outlier detection applied to SARS-CoV-2 nucleotide sequences can identify sequences of common variants and other variants of interest. BMC Bioinformatics. 2022 Dec 19; 23(1):547. PMID: 36536276; PMCID: PMC9761049.
    Citations:    Fields:    Translation:HumansCells
  9. Morris AH, Horvat C, Stagg B, Grainger DW, Lanspa M, Orme J, Clemmer TP, Weaver LK, Thomas FO, Grissom CK, Hirshberg E, East TD, Wallace CJ, Young MP, Sittig DF, Suchyta M, Pearl JE, Pesenti A, Bombino M, Beck E, Sward KA, Weir C, Phansalkar S, Bernard GR, Thompson BT, Brower R, Truwit J, Steingrub J, Hiten RD, Willson DF, Zimmerman JJ, Nadkarni V, Randolph AG, Curley MAQ, Newth CJL, Lacroix J, Agus MSD, Lee KH, deBoisblanc BP, Moore FA, Evans RS, Sorenson DK, Wong A, Boland MV, Dere WH, Crandall A, Facelli J, Huff SM, Haug PJ, Pielmeier U, Rees SE, Karbing DS, Andreassen S, Fan E, Goldring RM, Berger KI, Oppenheimer BW, Ely EW, Pickering BW, Schoenfeld DA, Tocino I, Gonnering RS, Pronovost PJ, Savitz LA, Dreyfuss D, Slutsky AS, Crapo JD, Pinsky MR, James B, Berwick DM. Computer clinical decision support that automates personalized clinical care: a challenging but needed healthcare delivery strategy. J Am Med Inform Assoc. 2022 Dec 13; 30(1):178-194. PMID: 36125018; PMCID: PMC9748596.
    Citations:    Fields:    
  10. Bodansky A, Vazquez SE, Chou J, Novak T, Al-Musa A, Young C, Newhams M, Kucukak S, Zambrano LD, Mitchell A, Wang CY, Moffitt K, Halasa NB, Loftis LL, Schwartz SP, Walker TC, Mack EH, Fitzgerald JC, Gertz SJ, Rowan CM, Irby K, Sanders RC, Kong M, Schuster JE, Staat MA, Zinter MS, Cvijanovich NZ, Tarquinio KM, Coates BM, Flori HR, Dahmer MK, Crandall H, Cullimore ML, Levy ER, Chatani B, Nofziger R, Geha RS, DeRisi J, Campbell AP, Anderson M, Randolph AG. NFKB2 haploinsufficiency identified via screening for IFNa2 autoantibodies in children and adolescents hospitalized with SARS-CoV-2-related complications. J Allergy Clin Immunol. 2022 Dec 09. PMID: 36509151; PMCID: PMC9733962.
    Citations:    Fields:    
  11. Lee S, Zhang Y, Newhams M, Novak T, Thomas PG, Mourani PM, Hall MW, Loftis LL, Cvijanovich NZ, Tarquinio KM, Schwarz AJ, Weiss SL, Thomas NJ, Markovitz B, Cullimore ML, Sanders RC, Zinter MS, Sullivan JE, Halasa NB, Bembea MM, Giuliano JS, Typpo KV, Nofziger RA, Shein SL, Kong M, Coates BM, Weiss ST, Lange C, Su HC, Randolph AG. DDX58 Is Associated With Susceptibility to Severe Influenza Virus Infection in Children and Adolescents. J Infect Dis. 2022 11 28; 226(11):2030-2036. PMID: 35986912.
    Citations:    Fields:    Translation:Humans
  12. Maddux AB, Grunwell JR, Newhams MM, Chen SR, Olson SM, Halasa NB, Weiss SL, Coates BM, Schuster JE, Hall MW, Nofziger RA, Flori HR, Gertz SJ, Kong M, Sanders RC, Irby K, Hume JR, Cullimore ML, Shein SL, Thomas NJ, Miller K, Patel M, Fitzpatrick AM, Phipatanakul W, Randolph AG. Association of Asthma With Treatments and Outcomes in Children With Critical Influenza. J Allergy Clin Immunol Pract. 2022 Nov 12. PMID: 36379408.
    Citations:    Fields:    
  13. Randolph AG, Bembea MM, Cheifetz IM, Curley MAQ, Flori HR, Khemani RG, Kudchadkar SR, Nishisaki A, Watson RS, Tucci M, Lacroix J, Thompson AE, Thomas NJ. Pediatric Acute Lung Injury and Sepsis Investigators (PALISI): Evolution of an Investigator-Initiated Research Network. Pediatr Crit Care Med. 2022 12 01; 23(12):1056-1066. PMID: 36454002; PMCID: PMC9747245.
    Citations:    Fields:    Translation:Humans
  14. Son MBF, Berbert L, Young C, Dallas J, Newhams M, Chen S, Ardoin SP, Basiaga ML, Canny SP, Crandall H, Dhakal S, Dhanrajani A, Sagcal-Gironella ACP, Hobbs CV, Huie L, James K, Jones M, Kim S, Lionetti G, Mannion ML, Muscal E, Prahalad S, Schulert GS, Tejtel KS, Villacis-Nunez DS, Wu EY, Zambrano LD, Campbell AP, Patel MM, Randolph AG. Postdischarge Glucocorticoid Use and Clinical Outcomes of Multisystem Inflammatory Syndrome in Children. JAMA Netw Open. 2022 11 01; 5(11):e2241622. PMID: 36367723; PMCID: PMC9652757.
    Citations:    Fields:    Translation:HumansPHPublic Health
  15. Sahni LC, Price AM, Olson SM, Newhams MM, Pannaraj PS, Maddux AB, Halasa NB, Bline KE, Cameron MA, Schwartz SP, Walker TC, Irby K, Chiotos K, Nofziger RA, Mack EH, Smallcomb L, Bradford TT, Kamidani S, Tarquinio KM, Cvijanovich NZ, Schuster JE, Bhumbra SS, Levy ER, Hobbs CV, Cullimore ML, Coates BM, Heidemann SM, Gertz SJ, Kong M, Flori HR, Staat MA, Zinter MS, Hume JR, Chatani BM, Gaspers MG, Maamari M, Randolph AG, Patel MM, Boom JA. Factors associated with COVID-19 non-vaccination in adolescents hospitalized without COVID-19. J Pediatric Infect Dis Soc. 2022 Oct 30. PMID: 36309873.
    Citations:    Fields:    
  16. Dionne A, Friedman KG, Young CC, Newhams MM, Kucukak S, Jackson AM, Fitzgerald JC, Smallcomb LS, Heidemann S, McLaughlin GE, Irby K, Bradford TT, Horwitz SM, Loftis LL, Soma VL, Rowan CM, Kong M, Halasa NB, Tarquinio KM, Schwarz AJ, Hume JR, Gertz SJ, Clouser KN, Carroll CL, Wellnitz K, Cullimore ML, Doymaz S, Levy ER, Typpo KV, Lansell AN, Butler AD, Kuebler JD, Zambrano LD, Campbell AP, Patel MM, Randolph AG, Newburger JW. Tachyarrhythmias During Hospitalization for COVID-19 or Multisystem Inflammatory Syndrome in Children and Adolescents. J Am Heart Assoc. 2022 10 18; 11(20):e025915. PMID: 36250670; PMCID: PMC9673680.
    Citations:    Fields:    Translation:Humans
  17. Sigal GB, Novak T, Mathew A, Chou J, Zhang Y, Manjula N, Bathala P, Joe J, Padmanabhan N, Romero D, Allegri-Machado G, Joerger J, Loftis LL, Schwartz SP, Walker TC, Fitzgerald JC, Tarquinio KM, Zinter MS, Schuster JE, Halasa NB, Cullimore ML, Maddux AB, Staat MA, Irby K, Flori HR, Coates BM, Crandall H, Gertz SJ, Randolph AG, Pollock NR. Measurement of Severe Acute Respiratory Syndrome Coronavirus 2 Antigens in Plasma of Pediatric Patients With Acute Coronavirus Disease 2019 or Multisystem Inflammatory Syndrome in Children Using an Ultrasensitive and Quantitative Immunoassay. Clin Infect Dis. 2022 10 12; 75(8):1351-1358. PMID: 35213684; PMCID: PMC8903440.
    Citations: 3     Fields:    
  18. Britto C, Mohorianu I, Yeung T, Cheung E, Novak T, Hall MW, Mourani PM, Weiss SL, Thomas NJ, Markovitz B, Randolph AG, Moffitt KL. Host Respiratory Transcriptome Signature Associated with Poor Outcome in Children with Influenza-Staphylococcus aureus Pneumonia. J Infect Dis. 2022 09 28; 226(7):1286-1294. PMID: 35899844.
    Citations:    Fields:    
  19. Pierce CA, Herold KC, Herold BC, Chou J, Randolph A, Kane B, McFarland S, Gurdasani D, Pagel C, Hotez P, Cobey S, Hensley SE. COVID-19 and children. Science. 2022 09 09; 377(6611):1144-1149. PMID: 36074833.
    Citations: 5     Fields:    Translation:HumansCellsPHPublic Health
  20. Zambrano LD, Ly KN, Link-Gelles R, Newhams MM, Akande M, Wu MJ, Feldstein LR, Tarquinio KM, Sahni LC, Riggs BJ, Singh AR, Fitzgerald JC, Schuster JE, Giuliano JS, Englund JA, Hume JR, Hall MW, Osborne CM, Doymaz S, Rowan CM, Babbitt CJ, Clouser KN, Horwitz SM, Chou J, Patel MM, Hobbs C, Randolph AG, Campbell AP. Investigating Health Disparities Associated With Multisystem Inflammatory Syndrome in Children After SARS-CoV-2 Infection. Pediatr Infect Dis J. 2022 11 01; 41(11):891-898. PMID: 36102740; PMCID: PMC9555608.
    Citations: 1     Fields:    Translation:HumansCells
  21. Maddux AB, Berbert L, Young CC, Feldstein LR, Zambrano LD, Kucukak S, Newhams MM, Miller K, FitzGerald MM, He J, Halasa NB, Cvijanovich NZ, Loftis LL, Walker TC, Schwartz SP, Gertz SJ, Tarquinio KM, Fitzgerald JC, Kong M, Schuster JE, Mack EH, Hobbs CV, Rowan CM, Staat MA, Zinter MS, Irby K, Crandall H, Flori H, Cullimore ML, Nofziger RA, Shein SL, Gaspers MG, Hume JR, Levy ER, Chen SR, Patel MM, Tenforde MW, Weller E, Campbell AP, Randolph AG. Health Impairments in Children and Adolescents After Hospitalization for Acute COVID-19 or MIS-C. Pediatrics. 2022 09 01; 150(3). PMID: 35765138.
    Citations:    Fields:    
  22. Lam KP, Chiñas M, Julé AM, Taylor M, Ohashi M, Benamar M, Crestani E, Son MBF, Chou J, Gebhart C, Chatila T, Newburger J, Randolph A, Gutierrez-Arcelus M, Henderson LA. SARS-CoV-2-specific T cell responses in patients with multisystem inflammatory syndrome in children. Clin Immunol. 2022 Oct; 243:109106. PMID: 36049601; PMCID: PMC9423880.
    Citations: 2     Fields:    Translation:HumansCells
  23. Olson SM, Newhams MM, Halasa NB, Feldstein LR, Novak T, Weiss SL, Coates BM, Schuster JE, Schwarz AJ, Maddux AB, Hall MW, Nofziger RA, Flori HR, Gertz SJ, Kong M, Sanders RC, Irby K, Hume JR, Cullimore ML, Shein SL, Thomas NJ, Stewart LS, Barnes JR, Patel MM, Randolph AG. Vaccine Effectiveness Against Life-Threatening Influenza Illness in US Children. Clin Infect Dis. 2022 08 25; 75(2):230-238. PMID: 35024795.
    Citations: 2     Fields:    
  24. Tang J, Novak T, Hecker J, Grubbs G, Zahra FT, Bellusci L, Pourhashemi S, Chou J, Moffitt K, Halasa NB, Schwartz SP, Walker TC, Tarquinio KM, Zinter MS, Staat MA, Gertz SJ, Cvijanovich NZ, Schuster JE, Loftis LL, Coates BM, Mack EH, Irby K, Fitzgerald JC, Rowan CM, Kong M, Flori HR, Maddux AB, Shein SL, Crandall H, Hume JR, Hobbs CV, Tremoulet AH, Shimizu C, Burns JC, Chen SR, Moon HK, Lange C, Randolph AG, Khurana S. Author Correction: Cross-reactive immunity against the SARS-CoV-2 Omicron variant is low in pediatric patients with prior COVID-19 or MIS-C. Nat Commun. 2022 Aug 12; 13(1):4732. PMID: 35961980.
    Citations:    Fields:    
  25. Zambrano LD, Newhams MM, Olson SM, Halasa NB, Price AM, Orzel AO, Young CC, Boom JA, Sahni LC, Maddux AB, Bline KE, Kamidani S, Tarquinio KM, Chiotos K, Schuster JE, Cullimore ML, Heidemann SM, Hobbs CV, Nofziger RA, Pannaraj PS, Cameron MA, Walker TC, Schwartz SP, Michelson KN, Coates BM, Flori HR, Mack EH, Smallcomb L, Gertz SJ, Bhumbra SS, Bradford TT, Levy ER, Kong M, Irby K, Cvijanovich NZ, Zinter MS, Bowens C, Crandall H, Hume JR, Patel MM, Campbell AP, Randolph AG. BNT162b2 mRNA Vaccination Against COVID-19 is Associated with Decreased Likelihood of Multisystem Inflammatory Syndrome in U.S. Children Ages 5-18 Years. Clin Infect Dis. 2022 Aug 04. PMID: 35924406.
    Citations: 1     Fields:    
  26. Melgar M, Seaby EG, McArdle AJ, Young CC, Campbell AP, Murray NL, Patel MM, Levin M, Randolph AG, Son MBF. Treatment of Multisystem Inflammatory Syndrome in Children: Understanding Differences in Results of Comparative Effectiveness Studies. ACR Open Rheumatol. 2022 Sep; 4(9):804-810. PMID: 35759535; PMCID: PMC9469482.
    Citations:    
  27. Halasa NB, Olson SM, Staat MA, Newhams MM, Price AM, Pannaraj PS, Boom JA, Sahni LC, Chiotos K, Cameron MA, Bline KE, Hobbs CV, Maddux AB, Coates BM, Michelson KN, Heidemann SM, Irby K, Nofziger RA, Mack EH, Smallcomb L, Schwartz SP, Walker TC, Gertz SJ, Schuster JE, Kamidani S, Tarquinio KM, Bhumbra SS, Maamari M, Hume JR, Crandall H, Levy ER, Zinter MS, Bradford TT, Flori HR, Cullimore ML, Kong M, Cvijanovich NZ, Gilboa SM, Polen KN, Campbell AP, Randolph AG, Patel MM. Maternal Vaccination and Risk of Hospitalization for Covid-19 among Infants. N Engl J Med. 2022 07 14; 387(2):109-119. PMID: 35731908; PMCID: PMC9342588.
    Citations: 1     Fields:    Translation:HumansCellsPHPublic Health
  28. Halasa NB, Spieker AJ, Young CC, Olson SM, Newhams MM, Amarin JZ, Moffitt KL, Nakamura MM, Levy ER, Soma VL, Talj R, Weiss SL, Fitzgerald JC, Mack EH, Maddux AB, Schuster JE, Coates BM, Hall MW, Schwartz SP, Schwarz AJ, Kong M, Spinella PC, Loftis LL, McLaughlin GE, Hobbs CV, Rowan CM, Bembea MM, Nofziger RA, Babbitt CJ, Bowens C, Flori HR, Gertz SJ, Zinter MS, Giuliano JS, Hume JR, Cvijanovich NZ, Singh AR, Crandall HA, Thomas NJ, Cullimore ML, Patel MM, Randolph AG. Life-Threatening Complications of Influenza versus COVID-19 in U.S. Children. Clin Infect Dis. 2022 Jun 19. PMID: 35717646; PMCID: PMC9384330.
    Citations:    Fields:    
  29. Schuster JE, Halasa NB, Nakamura M, Levy ER, Fitzgerald JC, Young CC, Newhams MM, Bourgeois F, Staat MA, Hobbs CV, Dapul H, Feldstein LR, Jackson AM, Mack EH, Walker TC, Maddux AB, Spinella PC, Loftis LL, Kong M, Rowan CM, Bembea MM, McLaughlin GE, Hall MW, Babbitt CJ, Maamari M, Zinter MS, Cvijanovich NZ, Michelson KN, Gertz SJ, Carroll CL, Thomas NJ, Giuliano JS, Singh AR, Hymes SR, Schwarz AJ, McGuire JK, Nofziger RA, Flori HR, Clouser KN, Wellnitz K, Cullimore ML, Hume JR, Patel M, Randolph AG. A Description of COVID-19-Directed Therapy in Children Admitted to US Intensive Care Units 2020. J Pediatric Infect Dis Soc. 2022 May 30; 11(5):191-198. PMID: 35022779; PMCID: PMC8807297.
    Citations:    Fields:    Translation:Humans
  30. Tang J, Novak T, Hecker J, Grubbs G, Zahra FT, Bellusci L, Pourhashemi S, Chou J, Moffitt K, Halasa NB, Schwartz SP, Walker TC, Tarquinio KM, Zinter MS, Staat MA, Gertz SJ, Cvijanovich NZ, Schuster JE, Loftis LL, Coates BM, Mack EH, Irby K, Fitzgerald JC, Rowan CM, Kong M, Flori HR, Maddux AB, Shein SL, Crandall H, Hume JR, Hobbs CV, Tremoulet AH, Shimizu C, Burns JC, Chen SR, Moon HK, Lange C, Randolph AG, Khurana S. Cross-reactive immunity against the SARS-CoV-2 Omicron variant is low in pediatric patients with prior COVID-19 or MIS-C. Nat Commun. 2022 05 27; 13(1):2979. PMID: 35624101; PMCID: PMC9142524.
    Citations:    Fields:    Translation:HumansCells
  31. Chatila TA, Benamar M, Chen Q, Chou J, Julé A, Boudra R, Contini P, Crestani E, Wang M, Fong J, Lai P, Rockwitz S, Lee P, Chan TMF, Altun EZ, Kepenekli E, Karakoc-Aydiner E, Ozen A, Boran P, Aygun F, Onal P, Sakalli AAK, Cokugras H, Gelmez M, Öktelik F, Cetin EA, Zhong Y, Taylor M, Irby K, Halasa N, Signa S, Prigione I, Gattorno M, Cotugno N, Amodio D, Geha R, Son MB, Newburger J, Agrawal P, Volpi S, Palma P, Kiykim A, Randolph A, Deniz G, Baris S, De Palma R, Schmitz-Abe K, Charbonnier LM, Henderson L. Notch1-CD22-Dependent Immune Dysregulation in the SARS-CoV2-Associated Multisystem Inflammatory Syndrome in Children. Res Sq. 2022 Apr 11. PMID: 35441180; PMCID: PMC9016654.
    Citations:    
  32. Price AM, Olson SM, Newhams MM, Halasa NB, Boom JA, Sahni LC, Pannaraj PS, Irby K, Bline KE, Maddux AB, Nofziger RA, Cameron MA, Walker TC, Schwartz SP, Mack EH, Smallcomb L, Schuster JE, Hobbs CV, Kamidani S, Tarquinio KM, Bradford TT, Levy ER, Chiotos K, Bhumbra SS, Cvijanovich NZ, Heidemann SM, Cullimore ML, Gertz SJ, Coates BM, Staat MA, Zinter MS, Kong M, Chatani BM, Hume JR, Typpo KV, Maamari M, Flori HR, Tenforde MW, Zambrano LD, Campbell AP, Patel MM, Randolph AG. BNT162b2 Protection against the Omicron Variant in Children and Adolescents. N Engl J Med. 2022 05 19; 386(20):1899-1909. PMID: 35353976; PMCID: PMC9006785.
    Citations: 8     Fields:    Translation:HumansCells
  33. Ostermann M, Randolph AG. Resuscitation Fluid Composition and Acute Kidney Injury in Critical Illness. N Engl J Med. 2022 03 03; 386(9):888-889. PMID: 35235731.
    Citations: 1     Fields:    Translation:Humans
  34. Hobbs CV, Woodworth K, Young CC, Jackson AM, Newhams MM, Dapul H, Maamari M, Hall MW, Maddux AB, Singh AR, Schuster JE, Rowan CM, Fitzgerald JC, Irby K, Kong M, Mack EH, Staat MA, Cvijanovich NZ, Bembea MM, Coates BM, Halasa NB, Walker TC, McLaughlin GE, Babbitt CJ, Nofziger RA, Loftis LL, Bradford TT, Campbell AP, Patel MM, Randolph AG. Frequency, Characteristics and Complications of COVID-19 in Hospitalized Infants. Pediatr Infect Dis J. 2022 03 01; 41(3):e81-e86. PMID: 34955519; PMCID: PMC8828316.
    Citations: 4     Fields:    Translation:HumansCellsPHPublic Health
  35. Zinter MS, McArthur J, Duncan C, Adams R, Kreml E, Dalton H, Abdel-Azim H, Rowan CM, Gertz SJ, Mahadeo KM, Randolph AG, Rajapreyar P, Steiner ME, Lehmann L. Candidacy for Extracorporeal Life Support in Children After Hematopoietic Cell Transplantation: A Position Paper From the Pediatric Acute Lung Injury and Sepsis Investigators Network's Hematopoietic Cell Transplant and Cancer Immunotherapy Subgroup. Pediatr Crit Care Med. 2022 03 01; 23(3):205-213. PMID: 34878420; PMCID: PMC8897218.
    Citations:    Fields:    Translation:Humans
  36. Halasa NB, Olson SM, Staat MA, Newhams MM, Price AM, Boom JA, Sahni LC, Cameron MA, Pannaraj PS, Bline KE, Bhumbra SS, Bradford TT, Chiotos K, Coates BM, Cullimore ML, Cvijanovich NZ, Flori HR, Gertz SJ, Heidemann SM, Hobbs CV, Hume JR, Irby K, Kamidani S, Kong M, Levy ER, Mack EH, Maddux AB, Michelson KN, Nofziger RA, Schuster JE, Schwartz SP, Smallcomb L, Tarquinio KM, Walker TC, Zinter MS, Gilboa SM, Polen KN, Campbell AP, Randolph AG, Patel MM. Effectiveness of Maternal Vaccination with mRNA COVID-19 Vaccine During Pregnancy Against COVID-19-Associated Hospitalization in Infants Aged <6 Months - 17 States, July 2021-January 2022. MMWR Morb Mortal Wkly Rep. 2022 Feb 18; 71(7):264-270. PMID: 35176002; PMCID: PMC8853480.
    Citations: 15     Fields:    Translation:HumansCells
  37. Tang J, Randolph AG, Novak T, Walker TC, Loftis LL, Zinter MS, Irby K, Khurana S. Systemic and Lower Respiratory Tract Immunity to SARS-CoV-2 Omicron and Variants in Pediatric Severe COVID-19 and Mis-C. Vaccines (Basel). 2022 Feb 10; 10(2). PMID: 35214728; PMCID: PMC8879098.
    Citations:    
  38. Chou J, Thomas PG, Randolph AG. Immunology of SARS-CoV-2 infection in children. Nat Immunol. 2022 02; 23(2):177-185. PMID: 35105983; PMCID: PMC8981222.
    Citations: 6     Fields:    Translation:HumansCells
  39. Zambrano LD, Newhams MM, Olson SM, Halasa NB, Price AM, Boom JA, Sahni LC, Kamidani S, Tarquinio KM, Maddux AB, Heidemann SM, Bhumbra SS, Bline KE, Nofziger RA, Hobbs CV, Bradford TT, Cvijanovich NZ, Irby K, Mack EH, Cullimore ML, Pannaraj PS, Kong M, Walker TC, Gertz SJ, Michelson KN, Cameron MA, Chiotos K, Maamari M, Schuster JE, Orzel AO, Patel MM, Campbell AP, Randolph AG. Effectiveness of BNT162b2 (Pfizer-BioNTech) mRNA Vaccination Against Multisystem Inflammatory Syndrome in Children Among Persons Aged 12-18 Years - United States, July-December 2021. MMWR Morb Mortal Wkly Rep. 2022 Jan 14; 71(2):52-58. PMID: 35025852; PMCID: PMC8757620.
    Citations: 41     Fields:    Translation:HumansCells
  40. Olson SM, Newhams MM, Halasa NB, Price AM, Boom JA, Sahni LC, Pannaraj PS, Irby K, Walker TC, Schwartz SP, Maddux AB, Mack EH, Bradford TT, Schuster JE, Nofziger RA, Cameron MA, Chiotos K, Cullimore ML, Gertz SJ, Levy ER, Kong M, Cvijanovich NZ, Staat MA, Kamidani S, Chatani BM, Bhumbra SS, Bline KE, Gaspers MG, Hobbs CV, Heidemann SM, Maamari M, Flori HR, Hume JR, Zinter MS, Michelson KN, Zambrano LD, Campbell AP, Patel MM, Randolph AG. Effectiveness of BNT162b2 Vaccine against Critical Covid-19 in Adolescents. N Engl J Med. 2022 02 24; 386(8):713-723. PMID: 35021004; PMCID: PMC8781318.
    Citations: 17     Fields:    Translation:HumansCells
  41. Blatz AM, Randolph AG. Severe COVID-19 and Multisystem Inflammatory Syndrome in Children in Children and Adolescents. Crit Care Clin. 2022 Jul; 38(3):571-586. PMID: 35667744; PMCID: PMC8743385.
    Citations:    Fields:    Translation:HumansCells
  42. Sahajpal NS, Jill Lai CY, Hastie A, Mondal AK, Dehkordi SR, van der Made CI, Fedrigo O, Al-Ajli F, Jalnapurkar S, Byrska-Bishop M, Kanagal-Shamanna R, Levy B, Schieck M, Illig T, Bacanu SA, Chou JS, Randolph AG, Rojiani AM, Zody MC, Brownstein CA, Beggs AH, Bafna V, Jarvis ED, Hoischen A, Chaubey A, Kolhe R. Optical genome mapping identifies rare structural variations as predisposition factors associated with severe COVID-19. iScience. 2022 Feb 18; 25(2):103760. PMID: 35036860; PMCID: PMC8744399.
    Citations: 1     
  43. Dionne A, Son MBF, Randolph AG. An Update on Multisystem Inflammatory Syndrome in Children Related to SARS-CoV-2. Pediatr Infect Dis J. 2022 01 01; 41(1):e6-e9. PMID: 34889873; PMCID: PMC8658063.
    Citations: 2     Fields:    Translation:Humans
  44. Poussaint TY, LaRovere KL, Newburger JW, Chou J, Nigrovic LE, Novak T, Randolph AG. Multisystem Inflammatory-like Syndrome in a Child Following COVID-19 mRNA Vaccination. Vaccines (Basel). 2021 Dec 30; 10(1). PMID: 35062704; PMCID: PMC8781649.
    Citations: 4     
  45. Feldstein LR, Ferdinands JM, Self WH, Randolph AG, Aboodi M, Baughman AH, Brown SM, Exline MC, Clark Files D, Gibbs K, Ginde AA, Gong MN, Grijalva CG, Halasa N, Khan A, Lindsell CJ, Newhams M, Peltan ID, Prekker ME, Rice TW, Shapiro NI, Steingrub J, Talbot HK, Halloran ME, Patel M. Modeling the Impacts of Clinical Influenza Testing on Influenza Vaccine Effectiveness Estimates. J Infect Dis. 2021 12 15; 224(12):2035-2042. PMID: 34013330; PMCID: PMC8967445.
    Citations: 2     Fields:    Translation:HumansPHPublic Health
  46. Sigal GB, Novak T, Mathew A, Chou J, Zhang Y, Manjula N, Bathala P, Joe J, Padmanabhan N, Romero D, Allegri-Machado G, Joerger J, Loftis LL, Schwartz SP, Walker TC, Fitzgerald JC, Tarquinio KM, Zinter MS, Schuster JE, Halasa NB, Cullimore ML, Maddux AB, Staat MA, Irby K, Flori HR, Coates BM, Crandall H, Gertz SJ, Randolph AG, Pollock NR. Measurement of SARS-CoV-2 antigens in plasma of pediatric patients with acute COVID-19 or MIS-C using an ultrasensitive and quantitative immunoassay. medRxiv. 2021 Dec 09. PMID: 34909787; PMCID: PMC8669854.
    Citations: 1     
  47. Chakrabarti A, Nguyen A, Newhams MM, Ohlson MB, Yang X, Ulufatu S, Liu S, Park S, Xu M, Jiang J, Halpern WG, Anania VG, McBride JM, Rosenberger CM, Randolph AG. Surfactant protein D is a biomarker of influenza-related pediatric lung injury. Pediatr Pulmonol. 2022 02; 57(2):519-528. PMID: 34842360; PMCID: PMC8792225.
    Citations:    Fields:    Translation:HumansAnimals
  48. Olson SM, Newhams MM, Halasa NB, Price AM, Boom JA, Sahni LC, Irby K, Walker TC, Schwartz SP, Pannaraj PS, Maddux AB, Bradford TT, Nofziger RA, Boutselis BJ, Cullimore ML, Mack EH, Schuster JE, Gertz SJ, Cvijanovich NZ, Kong M, Cameron MA, Staat MA, Levy ER, Chatani BM, Chiotos K, Zambrano LD, Campbell AP, Patel MM, Randolph AG. Effectiveness of Pfizer-BioNTech mRNA Vaccination Against COVID-19 Hospitalization Among Persons Aged 12-18 Years - United States, June-September 2021. MMWR Morb Mortal Wkly Rep. 2021 Oct 22; 70(42):1483-1488. PMID: 34673751; PMCID: PMC9361838.
    Citations: 27     Fields:    Translation:Humans
  49. Sauthier M, Tuli G, Jouvet PA, Brownstein JS, Randolph AG. Estimated Pao2: A Continuous and Noninvasive Method to Estimate Pao2 and Oxygenation Index. Crit Care Explor. 2021 Oct; 3(10):e0546. PMID: 34604787.
    Citations: 1     
  50. Geva A, Patel MM, Newhams MM, Young CC, Son MBF, Kong M, Maddux AB, Hall MW, Riggs BJ, Singh AR, Giuliano JS, Hobbs CV, Loftis LL, McLaughlin GE, Schwartz SP, Schuster JE, Babbitt CJ, Halasa NB, Gertz SJ, Doymaz S, Hume JR, Bradford TT, Irby K, Carroll CL, McGuire JK, Tarquinio KM, Rowan CM, Mack EH, Cvijanovich NZ, Fitzgerald JC, Spinella PC, Staat MA, Clouser KN, Soma VL, Dapul H, Maamari M, Bowens C, Havlin KM, Mourani PM, Heidemann SM, Horwitz SM, Feldstein LR, Tenforde MW, Newburger JW, Mandl KD, Randolph AG. Data-driven clustering identifies features distinguishing multisystem inflammatory syndrome from acute COVID-19 in children and adolescents. EClinicalMedicine. 2021 Oct; 40:101112. PMID: 34485878; PMCID: PMC8405351.
    Citations: 8     
  51. Son MBF, Newburger JW, Randolph AG. Therapy for Multisystem Inflammatory Syndrome in Children. Reply. N Engl J Med. 2021 09 23; 385(13):e42. PMID: 34379921.
    Citations:    Fields:    Translation:Humans
  52. Whitworth H, Sartain SE, Kumar R, Armstrong K, Ballester L, Betensky M, Cohen CT, Diaz R, Diorio C, Goldenberg NA, Jaffray J, Keegan J, Malone K, Randolph AG, Rifkin-Zenenberg S, Leung WS, Sochet A, Srivaths L, Zia A, Raffini L. Rate of thrombosis in children and adolescents hospitalized with COVID-19 or MIS-C. Blood. 2021 07 15; 138(2):190-198. PMID: 33895804; PMCID: PMC8079262.
    Citations: 33     Fields:    Translation:HumansCells
  53. Chou J, Platt CD, Habiballah S, Nguyen AA, Elkins M, Weeks S, Peters Z, Day-Lewis M, Novak T, Armant M, Williams L, Rockowitz S, Sliz P, Williams DA, Randolph AG, Geha RS. Mechanisms underlying genetic susceptibility to multisystem inflammatory syndrome in children (MIS-C). J Allergy Clin Immunol. 2021 09; 148(3):732-738.e1. PMID: 34224783; PMCID: PMC8252701.
    Citations: 23     Fields:    Translation:HumansCells
  54. Hahn G, Wu CM, Lee S, Lutz SM, Khurana S, Baden LR, Haneuse S, Qiao D, Hecker J, DeMeo DL, Tanzi RE, Choudhary MC, Etemad B, Mohammadi A, Esmaeilzadeh E, Cho MH, Li JZ, Randolph AG, Laird NM, Weiss ST, Silverman EK, Ribbeck K, Lange C. Genome-wide association analysis of COVID-19 mortality risk in SARS-CoV-2 genomes identifies mutation in the SARS-CoV-2 spike protein that colocalizes with P.1 of the Brazilian strain. Genet Epidemiol. 2021 10; 45(7):685-693. PMID: 34159627; PMCID: PMC8426743.
    Citations: 4     Fields:    Translation:HumansCells
  55. Son MBF, Murray N, Friedman K, Young CC, Newhams MM, Feldstein LR, Loftis LL, Tarquinio KM, Singh AR, Heidemann SM, Soma VL, Riggs BJ, Fitzgerald JC, Kong M, Doymaz S, Giuliano JS, Keenaghan MA, Hume JR, Hobbs CV, Schuster JE, Clouser KN, Hall MW, Smith LS, Horwitz SM, Schwartz SP, Irby K, Bradford TT, Maddux AB, Babbitt CJ, Rowan CM, McLaughlin GE, Yager PH, Maamari M, Mack EH, Carroll CL, Montgomery VL, Halasa NB, Cvijanovich NZ, Coates BM, Rose CE, Newburger JW, Patel MM, Randolph AG. Multisystem Inflammatory Syndrome in Children - Initial Therapy and Outcomes. N Engl J Med. 2021 07 01; 385(1):23-34. PMID: 34133855; PMCID: PMC8220972.
    Citations: 69     Fields:    Translation:HumansPHPublic Health
  56. Morris AH, Stagg B, Lanspa M, Orme J, Clemmer TP, Weaver LK, Thomas F, Grissom CK, Hirshberg E, East TD, Wallace CJ, Young MP, Sittig DF, Pesenti A, Bombino M, Beck E, Sward KA, Weir C, Phansalkar SS, Bernard GR, Taylor Thompson B, Brower R, Truwit JD, Steingrub J, Duncan Hite R, Willson DF, Zimmerman JJ, Nadkarni VM, Randolph A, Curley MAQ, Newth CJL, Lacroix J, Agus MSD, Lee KH, deBoisblanc BP, Scott Evans R, Sorenson DK, Wong A, Boland MV, Grainger DW, Dere WH, Crandall AS, Facelli JC, Huff SM, Haug PJ, Pielmeier U, Rees SE, Karbing DS, Andreassen S, Fan E, Goldring RM, Berger KI, Oppenheimer BW, Wesley Ely E, Gajic O, Pickering B, Schoenfeld DA, Tocino I, Gonnering RS, Pronovost PJ, Savitz LA, Dreyfuss D, Slutsky AS, Crapo JD, Angus D, Pinsky MR, James B, Berwick D. Enabling a learning healthcare system with automated computer protocols that produce replicable and personalized clinician actions. J Am Med Inform Assoc. 2021 06 12; 28(6):1330-1344. PMID: 33594410; PMCID: PMC8661391.
    Citations: 4     Fields:    Translation:Humans
  57. Toomey V, Randolph A, Bourgeois F, Graham D. Variation in Intravenous Acetaminophen Use in Pediatric Hospitals: Priorities for Standardization. Hosp Pediatr. 2021 07; 11(7):734-742. PMID: 34099460.
    Citations:    Fields:    Translation:Humans
  58. Payne AB, Gilani Z, Godfred-Cato S, Belay ED, Feldstein LR, Patel MM, Randolph AG, Newhams M, Thomas D, Magleby R, Hsu K, Burns M, Dufort E, Maxted A, Pietrowski M, Longenberger A, Bidol S, Henderson J, Sosa L, Edmundson A, Tobin-D'Angelo M, Edison L, Heidemann S, Singh AR, Giuliano JS, Kleinman LC, Tarquinio KM, Walsh RF, Fitzgerald JC, Clouser KN, Gertz SJ, Carroll RW, Carroll CL, Hoots BE, Reed C, Dahlgren FS, Oster ME, Pierce TJ, Curns AT, Langley GE, Campbell AP, Balachandran N, Murray TS, Burkholder C, Brancard T, Lifshitz J, Leach D, Charpie I, Tice C, Coffin SE, Perella D, Jones K, Marohn KL, Yager PH, Fernandes ND, Flori HR, Koncicki ML, Walker KS, Di Pentima MC, Li S, Horwitz SM, Gaur S, Coffey DC, Harwayne-Gidansky I, Hymes SR, Thomas NJ, Ackerman KG, Cholette JM. Incidence of Multisystem Inflammatory Syndrome in Children Among US Persons Infected With SARS-CoV-2. JAMA Netw Open. 2021 06 01; 4(6):e2116420. PMID: 34110391; PMCID: PMC8193431.
    Citations: 62     Fields:    Translation:HumansCells
  59. Feldstein LR, Self WH, Ferdinands JM, Randolph AG, Aboodi M, Baughman AH, Brown SM, Exline MC, Files DC, Gibbs K, Ginde AA, Gong MN, Grijalva CG, Halasa N, Khan A, Lindsell CJ, Newhams M, Peltan ID, Prekker ME, Rice TW, Shapiro NI, Steingrub J, Talbot HK, Halloran ME, Patel M. Incorporating Real-time Influenza Detection Into the Test-negative Design for Estimating Influenza Vaccine Effectiveness: The Real-time Test-negative Design (rtTND). Clin Infect Dis. 2021 05 04; 72(9):1669-1675. PMID: 32974644.
    Citations: 3     Fields:    Translation:HumansPHPublic Health
  60. LaRovere KL, Riggs BJ, Poussaint TY, Young CC, Newhams MM, Maamari M, Walker TC, Singh AR, Dapul H, Hobbs CV, McLaughlin GE, Son MBF, Maddux AB, Clouser KN, Rowan CM, McGuire JK, Fitzgerald JC, Gertz SJ, Shein SL, Munoz AC, Thomas NJ, Irby K, Levy ER, Staat MA, Tenforde MW, Feldstein LR, Halasa NB, Giuliano JS, Hall MW, Kong M, Carroll CL, Schuster JE, Doymaz S, Loftis LL, Tarquinio KM, Babbitt CJ, Nofziger RA, Kleinman LC, Keenaghan MA, Cvijanovich NZ, Spinella PC, Hume JR, Wellnitz K, Mack EH, Michelson KN, Flori HR, Patel MM, Randolph AG. Neurologic Involvement in Children and Adolescents Hospitalized in the United States for COVID-19 or Multisystem Inflammatory Syndrome. JAMA Neurol. 2021 05 01; 78(5):536-547. PMID: 33666649; PMCID: PMC7936352.
    Citations: 81     Fields:    Translation:Humans
  61. DeMerle KM, Angus DC, Baillie JK, Brant E, Calfee CS, Carcillo J, Chang CH, Dickson R, Evans I, Gordon AC, Kennedy J, Knight JC, Lindsell CJ, Liu V, Marshall JC, Randolph AG, Scicluna BP, Shankar-Hari M, Shapiro NI, Sweeney TE, Talisa VB, Tang B, Thompson BT, Tsalik EL, van der Poll T, van Vught LA, Wong HR, Yende S, Zhao H, Seymour CW. Sepsis Subclasses: A Framework for Development and Interpretation. Crit Care Med. 2021 05 01; 49(5):748-759. PMID: 33591001; PMCID: PMC8627188.
    Citations: 21     Fields:    Translation:Humans
  62. Feldstein LR, Tenforde MW, Friedman KG, Newhams M, Rose EB, Dapul H, Soma VL, Maddux AB, Mourani PM, Bowens C, Maamari M, Hall MW, Riggs BJ, Giuliano JS, Singh AR, Li S, Kong M, Schuster JE, McLaughlin GE, Schwartz SP, Walker TC, Loftis LL, Hobbs CV, Halasa NB, Doymaz S, Babbitt CJ, Hume JR, Gertz SJ, Irby K, Clouser KN, Cvijanovich NZ, Bradford TT, Smith LS, Heidemann SM, Zackai SP, Wellnitz K, Nofziger RA, Horwitz SM, Carroll RW, Rowan CM, Tarquinio KM, Mack EH, Fitzgerald JC, Coates BM, Jackson AM, Young CC, Son MBF, Patel MM, Newburger JW, Randolph AG. Characteristics and Outcomes of US Children and Adolescents With Multisystem Inflammatory Syndrome in Children (MIS-C) Compared With Severe Acute COVID-19. JAMA. 2021 03 16; 325(11):1074-1087. PMID: 33625505; PMCID: PMC7905703.
    Citations: 174     Fields:    Translation:Humans
  63. Boyd DF, Allen EK, Randolph AG, Guo XJ, Weng Y, Sanders CJ, Bajracharya R, Lee NK, Guy CS, Vogel P, Guan W, Li Y, Liu X, Novak T, Newhams MM, Fabrizio TP, Wohlgemuth N, Mourani PM, Wight TN, Schultz-Cherry S, Cormier SA, Shaw-Saliba K, Pekosz A, Rothman RE, Chen KF, Yang Z, Webby RJ, Zhong N, Crawford JC, Thomas PG. Publisher Correction: Exuberant fibroblast activity compromises lung function via ADAMTS4. Nature. 2020 Dec; 588(7836):E5. PMID: 33208953.
    Citations:    Fields:    
  64. Boyd DF, Allen EK, Randolph AG, Guo XJ, Weng Y, Sanders CJ, Bajracharya R, Lee NK, Guy CS, Vogel P, Guan W, Li Y, Liu X, Novak T, Newhams MM, Fabrizio TP, Wohlgemuth N, Mourani PM, Wight TN, Schultz-Cherry S, Cormier SA, Shaw-Saliba K, Pekosz A, Rothman RE, Chen KF, Yang Z, Webby RJ, Zhong N, Crawford JC, Thomas PG. Exuberant fibroblast activity compromises lung function via ADAMTS4. Nature. 2020 11; 587(7834):466-471. PMID: 33116313.
    Citations: 32     Fields:    Translation:HumansAnimalsCells
  65. Feldstein LR, Rose EB, Randolph AG. Multisystem Inflammatory Syndrome in Children in the United States. Reply. N Engl J Med. 2020 10 29; 383(18):1794-1795. PMID: 33085854.
    Citations: 7     Fields:    Translation:HumansPHPublic Health
  66. Horak RV, Alexander PM, Amirnovin R, Klein MJ, Bronicki RA, Markovitz BP, McBride ME, Randolph AG, Thiagarajan RR. Pediatric Cardiac Intensive Care Distribution, Service Delivery, and Staffing in the United States in 2018. Pediatr Crit Care Med. 2020 09; 21(9):797-803. PMID: 32886459.
    Citations: 1     Fields:    Translation:Humans
  67. Hwang TJ, Randolph AG, Bourgeois FT. Inclusion of Children in Clinical Trials of Treatments for Coronavirus Disease 2019 (COVID-19). JAMA Pediatr. 2020 Sep 01; 174(9):825-826. PMID: 32379296.
    Citations: 11     Fields:    Translation:HumansPHPublic Health
  68. Lee PY, Platt CD, Weeks S, Grace RF, Maher G, Gauthier K, Devana S, Vitali S, Randolph AG, McDonald DR, Geha RS, Chou J. Immune dysregulation and multisystem inflammatory syndrome in children (MIS-C) in individuals with haploinsufficiency of SOCS1. J Allergy Clin Immunol. 2020 11; 146(5):1194-1200.e1. PMID: 32853638; PMCID: PMC7445138.
    Citations: 31     Fields:    Translation:HumansCellsPHPublic Health
  69. Sauthier MS, Jouvet PA, Newhams MM, Randolph AG. Machine Learning Predicts Prolonged Acute Hypoxemic Respiratory Failure in Pediatric Severe Influenza. Crit Care Explor. 2020 Aug; 2(8):e0175. PMID: 32832912; PMCID: PMC7417145.
    Citations: 5     
  70. Feldstein LR, Rose EB, Horwitz SM, Collins JP, Newhams MM, Son MBF, Newburger JW, Kleinman LC, Heidemann SM, Martin AA, Singh AR, Li S, Tarquinio KM, Jaggi P, Oster ME, Zackai SP, Gillen J, Ratner AJ, Walsh RF, Fitzgerald JC, Keenaghan MA, Alharash H, Doymaz S, Clouser KN, Giuliano JS, Gupta A, Parker RM, Maddux AB, Havalad V, Ramsingh S, Bukulmez H, Bradford TT, Smith LS, Tenforde MW, Carroll CL, Riggs BJ, Gertz SJ, Daube A, Lansell A, Coronado Munoz A, Hobbs CV, Marohn KL, Halasa NB, Patel MM, Randolph AG. Multisystem Inflammatory Syndrome in U.S. Children and Adolescents. N Engl J Med. 2020 07 23; 383(4):334-346. PMID: 32598831; PMCID: PMC7346765.
    Citations: 764     Fields:    Translation:HumansCellsPHPublic Health
  71. Anania VG, Randolph AG, Yang X, Nguyen A, Newhams MM, Mathews WR, Rosenberger CM, McBride JM. Early Amplified Respiratory Bioactive Lipid Response Is Associated With Worse Outcomes in Pediatric Influenza-Related Respiratory Failure. Open Forum Infect Dis. 2020 May; 7(5):ofaa122. PMID: 32420403; PMCID: PMC7216777.
    Citations: 1     
  72. Novak T, Hall MW, McDonald DR, Newhams MM, Mistry AJ, Panoskaltsis-Mortari A, Mourani PM, Loftis LL, Weiss SL, Tarquinio KM, Markovitz B, Hartman ME, Schwarz A, Junger WG, Randolph AG. RIG-I and TLR4 responses and adverse outcomes in pediatric influenza-related critical illness. J Allergy Clin Immunol. 2020 06; 145(6):1673-1680.e11. PMID: 32035159; PMCID: PMC7323584.
    Citations: 2     Fields:    Translation:HumansCells
  73. Weiss SL, Peters MJ, Alhazzani W, Agus MSD, Flori HR, Inwald DP, Nadel S, Schlapbach LJ, Tasker RC, Argent AC, Brierley J, Carcillo J, Carrol ED, Carroll CL, Cheifetz IM, Choong K, Cies JJ, Cruz AT, De Luca D, Deep A, Faust SN, De Oliveira CF, Hall MW, Ishimine P, Javouhey E, Joosten KFM, Joshi P, Karam O, Kneyber MCJ, Lemson J, MacLaren G, Mehta NM, Møller MH, Newth CJL, Nguyen TC, Nishisaki A, Nunnally ME, Parker MM, Paul RM, Randolph AG, Ranjit S, Romer LH, Scott HF, Tume LN, Verger JT, Williams EA, Wolf J, Wong HR, Zimmerman JJ, Kissoon N, Tissieres P. Executive Summary: Surviving Sepsis Campaign International Guidelines for the Management of Septic Shock and Sepsis-Associated Organ Dysfunction in Children. Pediatr Crit Care Med. 2020 02; 21(2):186-195. PMID: 32032264.
    Citations: 9     Fields:    Translation:Humans
  74. Weiss SL, Peters MJ, Alhazzani W, Agus MSD, Flori HR, Inwald DP, Nadel S, Schlapbach LJ, Tasker RC, Argent AC, Brierley J, Carcillo J, Carrol ED, Carroll CL, Cheifetz IM, Choong K, Cies JJ, Cruz AT, De Luca D, Deep A, Faust SN, De Oliveira CF, Hall MW, Ishimine P, Javouhey E, Joosten KFM, Joshi P, Karam O, Kneyber MCJ, Lemson J, MacLaren G, Mehta NM, Møller MH, Newth CJL, Nguyen TC, Nishisaki A, Nunnally ME, Parker MM, Paul RM, Randolph AG, Ranjit S, Romer LH, Scott HF, Tume LN, Verger JT, Williams EA, Wolf J, Wong HR, Zimmerman JJ, Kissoon N, Tissieres P. Surviving Sepsis Campaign International Guidelines for the Management of Septic Shock and Sepsis-Associated Organ Dysfunction in Children. Pediatr Crit Care Med. 2020 02; 21(2):e52-e106. PMID: 32032273.
    Citations: 123     Fields:    Translation:Humans
  75. Weiss SL, Peters MJ, Alhazzani W, Agus MSD, Flori HR, Inwald DP, Nadel S, Schlapbach LJ, Tasker RC, Argent AC, Brierley J, Carcillo J, Carrol ED, Carroll CL, Cheifetz IM, Choong K, Cies JJ, Cruz AT, De Luca D, Deep A, Faust SN, De Oliveira CF, Hall MW, Ishimine P, Javouhey E, Joosten KFM, Joshi P, Karam O, Kneyber MCJ, Lemson J, MacLaren G, Mehta NM, Møller MH, Newth CJL, Nguyen TC, Nishisaki A, Nunnally ME, Parker MM, Paul RM, Randolph AG, Ranjit S, Romer LH, Scott HF, Tume LN, Verger JT, Williams EA, Wolf J, Wong HR, Zimmerman JJ, Kissoon N, Tissieres P. Executive summary: surviving sepsis campaign international guidelines for the management of septic shock and sepsis-associated organ dysfunction in children. Intensive Care Med. 2020 02; 46(Suppl 1):1-9. PMID: 32030528.
    Citations: 9     Fields:    Translation:Humans
  76. Weiss SL, Peters MJ, Alhazzani W, Agus MSD, Flori HR, Inwald DP, Nadel S, Schlapbach LJ, Tasker RC, Argent AC, Brierley J, Carcillo J, Carrol ED, Carroll CL, Cheifetz IM, Choong K, Cies JJ, Cruz AT, De Luca D, Deep A, Faust SN, De Oliveira CF, Hall MW, Ishimine P, Javouhey E, Joosten KFM, Joshi P, Karam O, Kneyber MCJ, Lemson J, MacLaren G, Mehta NM, Møller MH, Newth CJL, Nguyen TC, Nishisaki A, Nunnally ME, Parker MM, Paul RM, Randolph AG, Ranjit S, Romer LH, Scott HF, Tume LN, Verger JT, Williams EA, Wolf J, Wong HR, Zimmerman JJ, Kissoon N, Tissieres P. Surviving sepsis campaign international guidelines for the management of septic shock and sepsis-associated organ dysfunction in children. Intensive Care Med. 2020 02; 46(Suppl 1):10-67. PMID: 32030529.
    Citations: 89     Fields:    Translation:Humans
  77. Shein SL, Kong M, Toltzis P, Randolph AG. The authors reply. Pediatr Crit Care Med. 2019 08; 20(8):795-796. PMID: 31397821.
    Citations:    Fields:    Translation:HumansCells
  78. Horak RV, Griffin JF, Brown AM, Nett ST, Christie LM, Forbes ML, Kubis S, Li S, Singleton MN, Verger JT, Markovitz BP, Burns JP, Chung SA, Randolph AG. Growth and Changing Characteristics of Pediatric Intensive Care 2001-2016. Crit Care Med. 2019 08; 47(8):1135-1142. PMID: 31162205.
    Citations: 13     Fields:    Translation:Humans
  79. Cohen L, Fiore-Gartland A, Randolph AG, Panoskaltsis-Mortari A, Wong SS, Ralston J, Wood T, Seeds R, Huang QS, Webby RJ, Thomas PG, Hertz T. A Modular Cytokine Analysis Method Reveals Novel Associations With Clinical Phenotypes and Identifies Sets of Co-signaling Cytokines Across Influenza Natural Infection Cohorts and Healthy Controls. Front Immunol. 2019; 10:1338. PMID: 31275311.
    Citations: 13     Fields:    Translation:HumansCells
  80. Levy ER, Yip WK, Super M, Ferdinands JM, Mistry AJ, Newhams MM, Zhang Y, Su HC, McLaughlin GE, Sapru A, Loftis LL, Weiss SL, Hall MW, Cvijanovich N, Schwarz A, Tarquinio KM, Mourani PM, Randolph AG. Evaluation of Mannose Binding Lectin Gene Variants in Pediatric Influenza Virus-Related Critical Illness. Front Immunol. 2019; 10:1005. PMID: 31139182.
    Citations:    Fields:    Translation:HumansCellsCTClinical Trials
  81. Bourgeois FT, Graham DA, Kesselheim AS, Randolph AG. Cost Implications of Escalating Intravenous Acetaminophen Use in Children. JAMA Pediatr. 2019 05 01; 173(5):489-491. PMID: 30855654; PMCID: PMC6503505.
    Citations: 4     Fields:    Translation:Humans
  82. Matthay MA, Zemans RL, Zimmerman GA, Arabi YM, Beitler JR, Mercat A, Herridge M, Randolph AG, Calfee CS. Acute respiratory distress syndrome. Nat Rev Dis Primers. 2019 03 14; 5(1):18. PMID: 30872586; PMCID: PMC6709677.
    Citations: 465     Fields:    Translation:Humans
  83. Shein SL, Kong M, McKee B, O'Riordan M, Toltzis P, Randolph AG. Antibiotic Prescription in Young Children With Respiratory Syncytial Virus-Associated Respiratory Failure and Associated Outcomes. Pediatr Crit Care Med. 2019 02; 20(2):101-109. PMID: 30720644.
    Citations: 4     Fields:    Translation:Humans
  84. Randolph AG, Xu R, Novak T, Newhams MM, Bubeck Wardenburg J, Weiss SL, Sanders RC, Thomas NJ, Hall MW, Tarquinio KM, Cvijanovich N, Gedeit RG, Truemper EJ, Markovitz B, Hartman ME, Ackerman KG, Giuliano JS, Shein SL, Moffitt KL. Vancomycin Monotherapy May Be Insufficient to Treat Methicillin-resistant Staphylococcus aureus Coinfection in Children With Influenza-related Critical Illness. Clin Infect Dis. 2019 01 18; 68(3):365-372. PMID: 29893805.
    Citations: 18     Fields:    Translation:HumansCells
  85. Fiore-Gartland A, Panoskaltsis-Mortari A, Agan AA, Mistry AJ, Thomas PG, Matthay MA, Hertz T, Randolph AG. Cytokine Profiles of Severe Influenza Virus-Related Complications in Children. Front Immunol. 2017; 8:1423. PMID: 29163498; PMCID: PMC5681736.
    Citations: 16     Fields:    
  86. Randolph AG. A Biosignature Predicting Complicated Course in Children Presenting with Septic Shock. Why PERSEVERE? Am J Respir Crit Care Med. 2017 08 15; 196(4):411-413. PMID: 28809515; PMCID: PMC5564677.
    Citations:    Fields:    Translation:Humans
  87. Allen EK, Randolph AG, Bhangale T, Dogra P, Ohlson M, Oshansky CM, Zamora AE, Shannon JP, Finkelstein D, Dressen A, DeVincenzo J, Caniza M, Youngblood B, Rosenberger CM, Thomas PG. SNP-mediated disruption of CTCF binding at the IFITM3 promoter is associated with risk of severe influenza in humans. Nat Med. 2017 Aug; 23(8):975-983. PMID: 28714988; PMCID: PMC5702558.
    Citations: 84     Fields:    Translation:HumansCells
  88. Randolph AG, Yip WK, Allen EK, Rosenberger CM, Agan AA, Ash SA, Zhang Y, Bhangale TR, Finkelstein D, Cvijanovich NZ, Mourani PM, Hall MW, Su HC, Thomas PG. Evaluation of IFITM3 rs12252 Association With Severe Pediatric Influenza Infection. J Infect Dis. 2017 07 01; 216(1):14-21. PMID: 28531322; PMCID: PMC5853450.
    Citations: 31     Fields:    Translation:HumansCells
  89. Geva A, Landrigan CP, van der Velden MG, Randolph AG. Simulation of a Novel Schedule for Intensivist Staffing to Improve Continuity of Patient Care and Reduce Physician Burnout. Crit Care Med. 2017 Jul; 45(7):1138-1144. PMID: 28362643; PMCID: PMC5474184.
    Citations: 2     Fields:    Translation:Humans
  90. Randolph AG. Why So Few Randomized Trials in Pediatric Critical Care Medicine? Ask the Trialists. Pediatr Crit Care Med. 2017 05; 18(5):486-487. PMID: 28475531.
    Citations: 1     Fields:    Translation:Humans
  91. Madsen EC, Levy ER, Madden K, Agan AA, Sullivan RM, Graham DA, Randolph AG. Mannose-Binding Lectin Levels in Critically Ill Children With Severe Infections. Pediatr Crit Care Med. 2017 02; 18(2):103-111. PMID: 27820718.
    Citations: 2     Fields:    Translation:HumansCTClinical Trials
  92. Levy E, Zinter M, Madden K, Randolph A. 1444: MANNOSE-BINDING LECTIN AND PEDIATRIC SEPSIS SUSCEPTIBILITY: A SYSTEMATIC REVIEW AND META-ANALYSIS. Crit Care Med. 2016 Dec; 44(12 Suppl 1):436. PMID: 27851080.
    Citations:    
  93. Shein S, Kong M, McKee B, O'Riordan M, Randolph A. 933: ASSOCIATIONS BETWEEN PNEUMONIA AND CLINICAL OUTCOMES IN PICU PATIENTS WITH RSV BRONCHIOLITIS. Crit Care Med. 2016 Dec; 44(12 Suppl 1):309. PMID: 27850571.
    Citations:    
  94. Randolph AG. Enterovirus D68 Reemerges Globally as a Severe Pathogen Targeting Children. Pediatr Crit Care Med. 2016 11; 17(11):1088-1089. PMID: 27814328; PMCID: PMC6581449.
    Citations:    Fields:    Translation:HumansCellsPHPublic Health
  95. Roumeliotis N, Ducruet T, Bateman ST, Randolph AG, Lacroix J, Emeriaud G. Determinants of red blood cell transfusion in pediatric trauma patients admitted to the intensive care unit. Transfusion. 2017 01; 57(1):187-194. PMID: 27696446.
    Citations:    Fields:    Translation:HumansCTClinical Trials
  96. Yu KO, Randolph AG, Agan AA, Yip WK, Truemper EJ, Weiss SL, Ackerman KG, Schwarz AJ, Giuliano JS, Hall MW, Bubeck Wardenburg J. Staphylococcus aureus a-Toxin Response Distinguishes Respiratory Virus-Methicillin-Resistant S. aureus Coinfection in Children. J Infect Dis. 2016 Dec 01; 214(11):1638-1646. PMID: 27651418; PMCID: PMC5144732.
    Citations: 13     Fields:    Translation:HumansAnimalsCells
  97. Choong K, Duffett M, Cook DJ, Randolph AG. The Impact of Clinical Trials Conducted by Research Networks in Pediatric Critical Care. Pediatr Crit Care Med. 2016 09; 17(9):837-44. PMID: 27351267.
    Citations: 8     Fields:    Translation:Humans
  98. Skeens MA, McArthur J, Cheifetz IM, Duncan C, Randolph AG, Stanek J, Lehman L, Bajwa R. High Variability in the Reported Management of Hepatic Veno-Occlusive Disease in Children after Hematopoietic Stem Cell Transplantation. Biol Blood Marrow Transplant. 2016 10; 22(10):1823-1828. PMID: 27496218.
    Citations: 2     Fields:    Translation:Humans
  99. Tasker RC, Randolph AG. The authors reply. Pediatr Crit Care Med. 2016 06; 17(6):583-4. PMID: 27261660.
    Citations:    Fields:    
  100. Lee J, Faraoni D, Lee S, Brown M, Odegard K, Randolph A, DiNardo JA, Yuki K. Incidence and risk factors for postoperative vomiting following atrial septal defect repair in children. Paediatr Anaesth. 2016 Jun; 26(6):644-8. PMID: 27091811.
    Citations: 3     Fields:    Translation:Humans
  101. Randolph AG, Agan AA, Flanagan RF, Meece JK, Fitzgerald JC, Loftis LL, Truemper EJ, Li S, Ferdinands JM. Optimizing Virus Identification in Critically Ill Children Suspected of Having an Acute Severe Viral Infection. Pediatr Crit Care Med. 2016 Apr; 17(4):279-86. PMID: 26895562.
    Citations: 4     Fields:    Translation:HumansCells
  102. Randolph AG. Pragmatic trials in critically ill children are CATCHing on. Lancet. 2016 Apr 23; 387(10029):1697-8. PMID: 26946924.
    Citations: 2     Fields:    Translation:Humans
  103. Zgleszewski SE, Graham DA, Hickey PR, Brustowicz RM, Odegard KC, Koka R, Seefelder C, Navedo AT, Randolph AG. Anesthesiologist- and System-Related Risk Factors for Risk-Adjusted Pediatric Anesthesia-Related Cardiac Arrest. Anesth Analg. 2016 Feb; 122(2):482-9. PMID: 26554463.
    Citations: 3     Fields:    Translation:Humans
  104. Tasker RC, Randolph AG. Severity-of-Illness Scoring in Pediatric Critical Care: Quo Vadis? Pediatr Crit Care Med. 2016 Jan; 17(1):83-5. PMID: 26731320.
    Citations: 2     Fields:    Translation:Humans
  105. Torgerson DG, Giri T, Druley TE, Zheng J, Huntsman S, Seibold MA, Young AL, Schweiger T, Yin-Declue H, Sajol GD, Schechtman KB, Hernandez RD, Randolph AG, Bacharier LB, Castro M. Pooled Sequencing of Candidate Genes Implicates Rare Variants in the Development of Asthma Following Severe RSV Bronchiolitis in Infancy. PLoS One. 2015; 10(11):e0142649. PMID: 26587832; PMCID: PMC4654486.
    Citations: 7     Fields:    Translation:HumansCells
  106. Madden K, Feldman HA, Chun RF, Smith EM, Sullivan RM, Agan AA, Keisling SM, Panoskaltsis-Mortari A, Randolph AG. Critically Ill Children Have Low Vitamin D-Binding Protein, Influencing Bioavailability of Vitamin D. Ann Am Thorac Soc. 2015 Nov; 12(11):1654-61. PMID: 26356094.
    Citations: 25     Fields:    Translation:Humans
  107. Geva A, Tasker RC, Randolph AG. Therapeutic Hypothermia in Children. N Engl J Med. 2015 09 03; 373(10):979. PMID: 26332559.
    Citations:    Fields:    Translation:Humans
  108. Tasker RC, Randolph AG. Pediatric Pulseless Arrest With "Nonshockable" Rhythm: Does Faster Time to Epinephrine Improve Outcome? JAMA. 2015 Aug 25; 314(8):776-7. PMID: 26305646.
    Citations:    Fields:    Translation:Humans
  109. Yealy DM, Huang DT, Delaney A, Knight M, Randolph AG, Daniels R, Nutbeam T. Recognizing and managing sepsis: what needs to be done? BMC Med. 2015 Apr 27; 13:98. PMID: 25927426; PMCID: PMC4410741.
    Citations: 17     Fields:    Translation:Humans
  110. Randolph AG. The tremendous burden of sepsis on China's youngest children. Pediatr Crit Care Med. 2014 Nov; 15(9):896-7. PMID: 25370055.
    Citations:    Fields:    Translation:Humans
  111. Higgerson RA, Olsho LE, Christie LM, Rehder K, Doksum T, Gedeit R, Giuliano JS, Brennan B, Wendlandt R, Randolph AG. Variability in IRBs regarding parental acceptance of passive consent. Pediatrics. 2014 Aug; 134(2):e496-503. PMID: 25002659.
    Citations: 7     Fields:    Translation:Humans
  112. Faustino EV, Hanson S, Spinella PC, Tucci M, O'Brien SH, Nunez AR, Yung M, Truemper E, Qin L, Li S, Marohn K, Randolph AG. A multinational study of thromboprophylaxis practice in critically ill children. Crit Care Med. 2014 May; 42(5):1232-40. PMID: 24351371; PMCID: PMC4293013.
    Citations: 11     Fields:    Translation:Humans
  113. Randolph AG, Kornetsky S. More consistent site institutional review board (IRB) input-more consistent site IRB output. Crit Care Med. 2014 May; 42(5):1292-3. PMID: 24736342.
    Citations:    Fields:    Translation:Humans
  114. Ferdinands JM, Olsho LE, Agan AA, Bhat N, Sullivan RM, Hall M, Mourani PM, Thompson M, Randolph AG. Effectiveness of influenza vaccine against life-threatening RT-PCR-confirmed influenza illness in US children, 2010-2012. J Infect Dis. 2014 Sep 01; 210(5):674-83. PMID: 24676207.
    Citations: 53     Fields:    Translation:HumansAnimalsCells
  115. Goldstein B, Randolph AG. The authors reply. Pediatr Crit Care Med. 2014 Feb; 15(2):183. PMID: 24492192.
    Citations:    Fields:    Translation:Humans
  116. Valentine SL, Lightdale JR, Tran CM, Jiang H, Sloan SR, Kleinman ME, Randolph AG. Assessment of hemoglobin threshold for packed RBC transfusion in a medical-surgical PICU. Pediatr Crit Care Med. 2014 Feb; 15(2):e89-94. PMID: 24335991.
    Citations: 2     Fields:    Translation:Humans
  117. Randolph AG, Yip WK, Falkenstein-Hagander K, Weiss ST, Janssen R, Keisling S, Bont L. Vitamin D-binding protein haplotype is associated with hospitalization for RSV bronchiolitis. Clin Exp Allergy. 2014 Feb; 44(2):231-7. PMID: 24447085.
    Citations: 14     Fields:    Translation:HumansCells
  118. Randolph AG. Rigorous scoping review of randomized trials in pediatric critical care highlights need for a rigorous rethink. Crit Care. 2013 Dec 20; 17(6):1024. PMID: 24359621.
    Citations:    Fields:    Translation:Humans
  119. Randolph AG, McCulloh RJ. Pediatric sepsis: important considerations for diagnosing and managing severe infections in infants, children, and adolescents. Virulence. 2014 Jan 01; 5(1):179-89. PMID: 24225404.
    Citations: 46     Fields:    Translation:Humans