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Koichi Yuki, M.D.

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Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01GM127600 (YUKI, KOICHI) May 1, 2020 - Apr 30, 2023
    NIH/NIGMS
    Surgical site infections and the role of anesthesia and bacterial ion transporters
    Role: Principal Investigator
  2. R21HD099194 (YUKI, KOICHI) Apr 3, 2020 - Mar 31, 2022
    NIH/NICHD
    Neutrophil-mediated multiple organ dysfunction during sepsis
    Role: Principal Investigator
  3. R01GM118277 (YUKI, KOICHI) Apr 1, 2016 - Mar 31, 2021
    NIH/NIGMS
    The impact of anesthetic selection on sepsis outcome and its mechanism
    Role: Principal Investigator
  4. K08GM101345 (YUKI, KOICHI) Apr 1, 2012 - Mar 31, 2017
    NIH/NIGMS
    Immunomodulatory mechanism of volatile anesthetics
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Koutsogiannaki S, Bu W, Hou L, Shibamura-Fujiogi M, Ishida H, Ohto U, Eckenhoff RG, Yuki K. The effect of anesthetics on toll like receptor 9. FASEB J. 2020 Sep 09. PMID: 32901993.
    Citations:    
  2. Brustowicz RM, Yuki K. A Simple Screening Test of Filtration Efficiency for Protecting the Gas Sampling Line from CoronavirusUsing Fluorescent Microspheres. Paediatr Anaesth. 2020 Aug 04. PMID: 32748414.
    Citations:    
  3. Mitsui Y, Hou L, Huang X, Odegard KC, Pereira LM, Yuki K. Volatile Anesthetic Sevoflurane Attenuates Toll-Like Receptor 1/2 Activation. Anesth Analg. 2020 08; 131(2):631-639. PMID: 32149756.
    Citations:    
  4. Hou L, Yuki K. SerpinB1 expression in Th17 cells depends on hypoxia-inducible factor 1-alpha. Int Immunopharmacol. 2020 Oct; 87:106826. PMID: 32717567.
    Citations:    
  5. Yuki K, Hou L. Role of ß2 Integrins in Neutrophils and Sepsis. Infect Immun. 2020 May 20; 88(6). PMID: 32205406.
    Citations:    
  6. Shaw R, Tighe N, Odegard KC, Alexander P, Emani S, Yuki K. Intubation precautions in a pediatric patient with severe COVID-19. J Pediatr Surg Case Rep. 2020 Jul; 58:101495. PMID: 32455111.
    Citations:    
  7. Mitsui Y, Koutsogiannaki S, Fujiogi M, Yuki K. In Vitro Model of Stretch-Induced Lung Injury to Study Different Lung Ventilation Regimens and the Role of Sedatives. Transl Perioper Pain Med. 2020; 7(3):258-264. PMID: 32542183.
    Citations:    
  8. Yuki K, Fujiogi M, Koutsogiannaki S. COVID-19 pathophysiology: A review. Clin Immunol. 2020 06; 215:108427. PMID: 32325252.
    Citations:    
  9. Yuki K. Anesthetic Management for Heart Transplantation in Adults with Congenital Heart Disease. Transl Perioper Pain Med. 2020; 7(3):248-252. PMID: 32377555.
    Citations:    
  10. Yuki K, Bu W, Eckenhoff RG, Yokomizo T, Okuno T. The role of propofol hydroxyl group in 5-lipoxygenase recognition. Biochem Biophys Res Commun. 2020 May 14; 525(4):909-914. PMID: 32171526.
    Citations:    
  11. Yuki K, Scholl R. Should we Routinely Reverse Neuromuscular Blockade with Sugammadex in Patients with a History of Heart Transplantation? Transl Perioper Pain Med. 2020; 7(2):185-189. PMID: 32039284.
    Citations:    
  12. Lee Y, Banooni A, Yuki K, Staffa SJ, DiNardo JA, Brown ML. Incidence and predictors of postoperative nausea and vomiting in children undergoing electrophysiology ablation procedures. Paediatr Anaesth. 2020 02; 30(2):147-152. PMID: 31869854.
    Citations:    
  13. Okuno T, Koutsogiannaki S, Hou L, Bu W, Ohto U, Eckenhoff RG, Yokomizo T, Yuki K. Volatile anesthetics isoflurane and sevoflurane directly target and attenuate Toll-like receptor 4 system. FASEB J. 2019 12; 33(12):14528-14541. PMID: 31675483.
    Citations:    
  14. Hou L, Rao DA, Yuki K, Cooley J, Henderson LA, Jonsson AH, Kaiserman D, Gorman MP, Nigrovic PA, Bird PI, Becher B, Remold-O'Donnell E. SerpinB1 controls encephalitogenic T helper cells in neuroinflammation. Proc Natl Acad Sci U S A. 2019 10 08; 116(41):20635-20643. PMID: 31548399.
    Citations:    
  15. Koutsogiannaki S, Hou L, Babazada H, Okuno T, Blazon-Brown N, Soriano SG, Yokomizo T, Yuki K. The volatile anesthetic sevoflurane reduces neutrophil apoptosis via Fas death domain-Fas-associated death domain interaction. FASEB J. 2019 11; 33(11):12668-12679. PMID: 31513427.
    Citations:    
  16. Kwon R, Koutsogiannaki S, Staffa SJ, Yuki K. The Outcomes of Pediatric Hematopoietic Stem Cell Transplantation Recipients Requiring Intensive Care Unit Admission- A Single Center Experience. Transl Perioper Pain Med. 2019; 6(3):75-80. PMID: 31304194.
    Citations:    
  17. Zha H, Matsunami E, Blazon-Brown N, Koutsogiannaki S, Hou L, Bu W, Babazada H, Odegard KC, Liu R, Eckenhoff RG, Yuki K. Volatile anesthetics affect macrophage phagocytosis. PLoS One. 2019; 14(5):e0216163. PMID: 31071106.
    Citations:    
  18. Koutsogiannaki S, Shimaoka M, Yuki K. The Use of Volatile Anesthetics as Sedatives for Acute Respiratory Distress Syndrome. Transl Perioper Pain Med. 2019; 6(2):27-38. PMID: 30923729.
    Citations:    
  19. Koutsogiannaki S, Bernier R, Tazawa K, Yuki K. Volatile Anesthetic Attenuates Phagocyte Function and Worsens Bacterial Loads in Wounds. J Surg Res. 2019 01; 233:323-330. PMID: 30502266.
    Citations:    Fields:    
  20. Lee S, Reddington E, Koutsogiannaki S, Hernandez MR, Odegard KC, DiNardo JA, Yuki K. Incidence and Risk Factors for Perioperative Cardiovascular and Respiratory Adverse Events in Pediatric Patients With Congenital Heart Disease Undergoing Noncardiac Procedures. Anesth Analg. 2018 09; 127(3):724-729. PMID: 29734243.
    Citations:    Fields:    
  21. Yuki K, Lee S, Staffa SJ, DiNardo JA. Induction techniques for pediatric patients with congenital heart disease undergoing noncardiac procedures are influenced by cardiac functional status and residual lesion burden. J Clin Anesth. 2018 Nov; 50:14-17. PMID: 29936283.
    Citations:    Fields:    
  22. Koutsogiannaki S, Zha H, Yuki K. Volatile Anesthetic Isoflurane Attenuates Liver Injury in Experimental Polymicrobial Sepsis Model. Transl Perioper Pain Med. 2018; 5(3):63-74. PMID: 29977977.
    Citations:    
  23. Yuki K, Koutsogiannaki S, Lee S, DiNardo JA. Unanticipated hospital admission in pediatric patients with congenital heart disease undergoing ambulatory noncardiac surgical procedures. Paediatr Anaesth. 2018 07; 28(7):607-611. PMID: 29777565.
    Citations:    Fields:    
  24. Aubrey J, Zha H, Yuki K. Incidence and Risk Factors of Perioperative Mortality in Pediatric ICU Patients. Transl Perioper Pain Med. 2018; 5(2):49-54. PMID: 29977976.
    Citations:    
  25. Sen M, Koksal AC, Yuki K, Wang J, Springer TA. Ligand- and cation-induced structural alterations of the leukocyte integrin LFA-1. J Biol Chem. 2018 04 27; 293(17):6565-6577. PMID: 29507098.
    Citations:    Fields:    Translation:HumansCells
  26. Fang ZA, Ghelani SJ, Koutsogiannaki S, DiNardo JA, Yuki K. Validation of a Mathematical Model of Bidirectional Glenn Circulation With Aortopulmonary Collaterals and the Implications for QP/QS Calculation. J Cardiothorac Vasc Anesth. 2018 02; 32(1):395-401. PMID: 29174747.
    Citations:    Fields:    Translation:Humans
  27. Koutsogiannaki S, Schaefers MM, Okuno T, Ohba M, Yokomizo T, Priebe GP, DiNardo JA, Sulpicio SG, Yuki K. From the Cover: Prolonged Exposure to Volatile Anesthetic Isoflurane Worsens the Outcome of Polymicrobial Abdominal Sepsis. Toxicol Sci. 2017 04 01; 156(2):402-411. PMID: 28003439.
    Citations: 2     Fields:    Translation:Animals
  28. Ferradal SL, Yuki K, Vyas R, Ha CG, Yi F, Stopp C, Wypij D, Cheng HH, Newburger JW, Kaza AK, Franceschini MA, Kussman BD, Grant PE. Non-invasive Assessment of Cerebral Blood Flow and Oxygen Metabolism in Neonates during Hypothermic Cardiopulmonary Bypass: Feasibility and Clinical Implications. Sci Rep. 2017 03 09; 7:44117. PMID: 28276534.
    Citations: 3     Fields:    Translation:HumansCTClinical Trials
  29. Chamberlain M, Koutsogiannaki S, Schaefers M, Babazada H, Liu R, Yuki K. The Differential Effects of Anesthetics on Bacterial Behaviors. PLoS One. 2017; 12(1):e0170089. PMID: 28099463.
    Citations:    Fields:    Translation:Cells
  30. Okuno T, Koutsogiannaki S, Ohba M, Chamberlain M, Bu W, Lin FY, Eckenhoff RG, Yokomizo T, Yuki K. Intravenous anesthetic propofol binds to 5-lipoxygenase and attenuates leukotriene B4 production. FASEB J. 2017 04; 31(4):1584-1594. PMID: 28069825.
    Citations:    Fields:    Translation:HumansAnimalsCells
  31. Yuki K, Matsunami E, Tazawa K, Wang W, DiNardo JA, Koutsogiannaki S. Pediatric Perioperative Stress Responses and Anesthesia. Transl Perioper Pain Med. 2017; 2(1):1-12. PMID: 28217718.
    Citations: 1     
  32. Tazawa K, Koutsogiannaki S, Chamberlain M, Yuki K. The effect of different anesthetics on tumor cytotoxicity by natural killer cells. Toxicol Lett. 2017 Jan 15; 266:23-31. PMID: 27940100.
    Citations:    Fields:    Translation:HumansCells
  33. Williams MR, Atkinson DB, Bezzerides VJ, Yuki K, Franklin K, Casta A, Alexander ME. Pausing With the Gauze: Inhibition of Temporary Pacemakers by Radiofrequency Scan During Cardiac Surgery. Anesth Analg. 2016 11; 123(5):1143-1148. PMID: 27644061.
    Citations:    Fields:    Translation:Humans
  34. Liu JR, Yuki K, Baek C, Han XH, Soriano SG. Dexmedetomidine-Induced Neuroapoptosis Is Dependent on Its Cumulative Dose. Anesth Analg. 2016 10; 123(4):1008-17. PMID: 27529322.
    Citations: 2     Fields:    Translation:AnimalsCells
  35. Yuki K, Eckenhoff RG. Mechanisms of the Immunological Effects of Volatile Anesthetics: A Review. Anesth Analg. 2016 08; 123(2):326-35. PMID: 27308954.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  36. Lee J, Faraoni D, Lee S, Brown M, Odegard K, Randolph A, DiNardo JA, Yuki K. Incidence and risk factors for postoperative vomiting following atrial septal defect repair in children. Paediatr Anaesth. 2016 Jun; 26(6):644-8. PMID: 27091811.
    Citations:    Fields:    Translation:Humans
  37. Faraoni D, Zurakowski D, Vo D, Goobie SM, Yuki K, Brown ML, DiNardo JA. Post-Operative Outcomes in Children With and Without Congenital Heart Disease Undergoing Noncardiac Surgery. J Am Coll Cardiol. 2016 Feb 23; 67(7):793-801. PMID: 26892415.
    Citations: 5     Fields:    Translation:Humans
  38. Greenwald E, Yuki K. A translational consideration of intercellular adhesion molecule-1 biology in the perioperative setting. Transl Perioper Pain Med. 2016; 1(2):17-23. PMID: 27182533.
    Citations: 1     
  39. Liu JR, Han X, Soriano SG, Yuki K. Leukocyte function-associated antigen-1 deficiency impairs responses to polymicrobial sepsis. World J Clin Cases. 2015 Sep 16; 3(9):793-806. PMID: 26380827.
    Citations: 2     
  40. Whiting D, Yuki K, DiNardo JA. Cardiopulmonary bypass in the pediatric population. Best Pract Res Clin Anaesthesiol. 2015 Jun; 29(2):241-56. PMID: 26060033.
    Citations: 1     Fields:    Translation:Humans
  41. Jung S, Yuki K. Differential effects of volatile anesthetics on leukocyte integrin macrophage-1 antigen. J Immunotoxicol. 2016; 13(2):148-56. PMID: 25746395.
    Citations: 3     Fields:    Translation:HumansCells
  42. Yuki K, Murakami N. Sepsis pathophysiology and anesthetic consideration. Cardiovasc Hematol Disord Drug Targets. 2015; 15(1):57-69. PMID: 25567335.
    Citations: 1     Fields:    Translation:HumansAnimals
  43. Liu JR, Han X, Soriano SG, Yuki K. The role of macrophage 1 antigen in polymicrobial sepsis. Shock. 2014 Dec; 42(6):532-9. PMID: 25075642.
    Citations: 6     Fields:    Translation:AnimalsCells
  44. Yuki K, DiNardo JA. Comparison of actual oxygen delivery kinetics to those predicted by mathematical modeling following stage 1 palliation just prior to superior cavopulmonary anastomosis. Paediatr Anaesth. 2015 Feb; 25(2):174-9. PMID: 25164862.
    Citations:    Fields:    Translation:Humans
  45. Bu W, Pereira LM, Eckenhoff RG, Yuki K. Stereoselectivity of isoflurane in adhesion molecule leukocyte function-associated antigen-1. PLoS One. 2014; 9(5):e96649. PMID: 24801074.
    Citations: 1     Fields:    Translation:HumansCells
  46. Kollmann CS, Bai X, Tsai CH, Yang H, Lind KE, Skinner SR, Zhu Z, Israel DI, Cuozzo JW, Morgan BA, Yuki K, Xie C, Springer TA, Shimaoka M, Evindar G. Application of encoded library technology (ELT) to a protein-protein interaction target: discovery of a potent class of integrin lymphocyte function-associated antigen 1 (LFA-1) antagonists. Bioorg Med Chem. 2014 Apr 01; 22(7):2353-65. PMID: 24593905.
    Citations: 10     Fields:    Translation:HumansCells
  47. Sen M, Yuki K, Springer TA. An internal ligand-bound, metastable state of a leukocyte integrin, aXß2. J Cell Biol. 2013 Nov 25; 203(4):629-42. PMID: 24385486.
    Citations: 18     Fields:    Translation:HumansAnimalsCells
  48. Yuki K, Bu W, Xi J, Shimaoka M, Eckenhoff R. Propofol shares the binding site with isoflurane and sevoflurane on leukocyte function-associated antigen-1. Anesth Analg. 2013 Oct; 117(4):803-11. PMID: 23960033.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  49. Yuki K, Bu W, Shimaoka M, Eckenhoff R. Volatile anesthetics, not intravenous anesthetic propofol bind to and attenuate the activation of platelet receptor integrin aIIbß3. PLoS One. 2013; 8(4):e60415. PMID: 23573252.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  50. Bertolizio G, Yuki K, Odegard K, Collard V, Dinardo J. Cardiac arrest and neuromuscular blockade reversal agents in the transplanted heart. J Cardiothorac Vasc Anesth. 2013 Dec; 27(6):1374-8. PMID: 23164506.
    Citations: 2     Fields:    Translation:Humans
  51. Carbo C, Yuki K, Demers M, Wagner DD, Shimaoka M. Isoflurane inhibits neutrophil recruitment in the cutaneous Arthus reaction model. J Anesth. 2013 Apr; 27(2):261-8. PMID: 23096126.
    Citations: 11     Fields:    Translation:Animals
  52. Yuki K, Bu W, Xi J, Sen M, Shimaoka M, Eckenhoff RG. Isoflurane binds and stabilizes a closed conformation of the leukocyte function-associated antigen-1. FASEB J. 2012 Nov; 26(11):4408-17. PMID: 22815384.
    Citations: 16     Fields:    Translation:HumansCells
  53. Yuki K, Emani S, DiNardo JA. A mathematical model of transitional circulation toward biventricular repair in hypoplastic left heart syndrome. Anesth Analg. 2012 Sep; 115(3):618-26. PMID: 22729965.
    Citations: 1     Fields:    Translation:Humans
  54. Yuki K, Sharma R, DiNardo J. Ventricular-assist device therapy in children. Best Pract Res Clin Anaesthesiol. 2012 Jun; 26(2):247-64. PMID: 22910093.
    Citations:    Fields:    Translation:Humans
  55. Ishigaki D, Okuyama H, Yuki K, Sato Y, Ogawa N, Hirono O, Kubota I. Serial evaluation of left ventricular contraction and relaxation in Takotsubo cardiomyopathy by 2D speckle tracking echocardiography. J Med Ultrason (2001). 2012 Oct; 39(4):265-9. PMID: 27279115.
    Citations: 1     Fields:    
  56. Collard V, Segura LG, Daaboul DG, Yuki K. Retrograde intubation during laryngeal cleft repair on cardiopulmonary bypass. J Anesth. 2012 Apr; 26(2):273-4. PMID: 22302106.
    Citations: 1     Fields:    Translation:Humans
  57. Yuki K, Chilson K, DiNardo JA. Improvement of PaO2 during one-lung ventilation with partial left-heart bypass in pediatric patients is caused by increased blood flow to the dependent lung. J Cardiothorac Vasc Anesth. 2013 Jun; 27(3):542-5. PMID: 22285126.
    Citations:    Fields:    Translation:Humans
  58. Yuki K. Cell-free ligand-binding assays for integrin LFA-1. Methods Mol Biol. 2012; 757:73-8. PMID: 21909907.
    Citations:    Fields:    Translation:HumansCells
  59. Koeberle A, Shindou H, Harayama T, Yuki K, Shimizu T. Polyunsaturated fatty acids are incorporated into maturating male mouse germ cells by lysophosphatidic acid acyltransferase 3. FASEB J. 2012 Jan; 26(1):169-80. PMID: 21968070.
    Citations: 12     Fields:    Translation:AnimalsCells
  60. Wesley MC, Yuki K, Daaboul DG, Dinardo JA. Blood utilization in neonates and infants undergoing cardiac surgery requiring cardiopulmonary bypass. World J Pediatr Congenit Heart Surg. 2011 Jul 01; 2(3):382-92. PMID: 23803991.
    Citations: 1     Fields:    
  61. Daaboul DG, Yuki K, Wesley MC, Dinardo JA. Anesthetic and cardiopulmonary bypass considerations for cardiac surgery in unique pediatric patient populations: sickle cell disease and cold agglutinin disease. World J Pediatr Congenit Heart Surg. 2011 Jul 01; 2(3):364-70. PMID: 23803987.
    Citations:    Fields:    
  62. Yuki K, Daaboul DG. Postoperative maladaptive behavioral changes in children. Middle East J Anaesthesiol. 2011 Jun; 21(2):183-9. PMID: 22435270.
    Citations: 3     Fields:    Translation:Humans
  63. Yuki K, Soriano SG, Shimaoka M. Sedative drug modulates T-cell and lymphocyte function-associated antigen-1 function. Anesth Analg. 2011 Apr; 112(4):830-8. PMID: 21385989.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  64. Yuki K, Casta A, Uezono S. Anesthetic management of noncardiac surgery for patients with single ventricle physiology. J Anesth. 2011 Apr; 25(2):247-56. PMID: 21197552.
    Citations: 5     Fields:    Translation:Humans
  65. Yuki K, Astrof NS, Bracken C, Soriano SG, Shimaoka M. Sevoflurane binds and allosterically blocks integrin lymphocyte function-associated antigen-1. Anesthesiology. 2010 Sep; 113(3):600-9. PMID: 20693879.
    Citations: 18     Fields:    Translation:HumansCells
  66. Okuyama H, Hirono O, Ishigaki D, Yuki K, Kubota I. Percutaneous transvenous stent implantation to external iliac vein stenosis in a patient with retroperitoneal fibrosis. Intern Med. 2010; 49(10):913-8. PMID: 20467176.
    Citations:    Fields:    Translation:Humans
  67. Yuki K, Sakuramoto C, Matsumoto C, Hoshino M, Niimi Y. The effect of left heart bypass on pulmonary blood flow and arterial oxygenation during one-lung ventilation in patients undergoing descending thoracic aortic surgery. J Clin Anesth. 2009 Dec; 21(8):562-6. PMID: 20122587.
    Citations:    Fields:    Translation:Humans
  68. Yuki K, Casta A. Management of difficult airway in pediatric patients with right ventricular outflow tract obstruction. J Anesth. 2009; 23(2):281-3. PMID: 19444572.
    Citations:    Fields:    Translation:Humans
  69. Yuki K, Shindou H, Hishikawa D, Shimizu T. Characterization of mouse lysophosphatidic acid acyltransferase 3: an enzyme with dual functions in the testis. J Lipid Res. 2009 May; 50(5):860-9. PMID: 19114731.
    Citations: 19     Fields:    Translation:AnimalsCells
  70. Shindou H, Hishikawa D, Harayama T, Yuki K, Shimizu T. Recent progress on acyl CoA: lysophospholipid acyltransferase research. J Lipid Res. 2009 Apr; 50 Suppl:S46-51. PMID: 18931347.
    Citations: 75     Fields:    Translation:HumansAnimals
  71. Yuki K, Astrof NS, Bracken C, Yoo R, Silkworth W, Soriano SG, Shimaoka M. The volatile anesthetic isoflurane perturbs conformational activation of integrin LFA-1 by binding to the allosteric regulatory cavity. FASEB J. 2008 Dec; 22(12):4109-16. PMID: 18708587.
    Citations: 21     Fields:    Translation:HumansCells
  72. Yuki K, Chilson K, Odegard KC, DiNardo JA. Trendelenburg position, simulated Valsalva maneuver, and liver compression do not alter the size of the right internal jugular vein in patients with a bidirectional Glenn shunt. Anesth Analg. 2007 Aug; 105(2):365-8. PMID: 17646491.
    Citations:    Fields:    Translation:Humans
  73. Yuki K, Shamberger RC, McGowan FX, Seefelder C. The perioperative management of a patient with Fontan physiology for pheochromocytoma resection. J Cardiothorac Vasc Anesth. 2008 Oct; 22(5):748-50. PMID: 18922437.
    Citations: 4     Fields:    Translation:Humans
  74. Casta A, Brown DW, Yuki K. Induction of supraventricular tachycardia during transesophageal echocardiography: an unusual complication. J Cardiothorac Vasc Anesth. 2008 Aug; 22(4):592-3. PMID: 18662640.
    Citations: 1     Fields:    Translation:Humans
  75. Kakinuma Y, Miyauchi T, Suzuki T, Yuki K, Murakoshi N, Goto K, Yamaguchi I. Enhancement of glycolysis in cardiomyocytes elevates endothelin-1 expression through the transcriptional factor hypoxia-inducible factor-1 alpha. Clin Sci (Lond). 2002 Aug; 103 Suppl 48:210S-214S. PMID: 12193088.
    Citations: 5     Fields:    Translation:AnimalsCells
  76. Yuki K, Suzuki T, Katoh S, Kakinuma Y, Miyauchi T, Mitsui Y. Endothelin-1 stimulates cardiomyocyte injury during mitochondrial dysfunction in culture. Eur J Pharmacol. 2001 Nov 16; 431(2):163-70. PMID: 11728422.
    Citations: 2     Fields:    Translation:AnimalsCells
  77. Fujiwara S, Takeishi Y, Hirono O, Fukui A, Okuyama M, Yamaguchi S, Ito M, Kaneko K, Shishido T, Miyamoto T, Yuki K, Miyashita T, Takahashi K, Minamihaba O, Tomoike H, Yamauchi S, Fatema K. Reverse redistribution of 99m Tc-sestamibi after direct percutaneous transluminal coronary angioplasty in acute myocardial infarction: relationship with wall motion and functional response to dobutamine stimulation. Nucl Med Commun. 2001 Nov; 22(11):1223-30. PMID: 11606888.
    Citations: 6     Fields:    Translation:Humans
  78. Kumagai Y, Hayashi T, Miyauchi T, Endo A, Iguchi A, Kiriya-Sakai M, Sakai S, Yuki K, Kikushima M, Shimojo N. Phenanthraquinone inhibits eNOS activity and suppresses vasorelaxation. . 2001 Jul; 281(1):R25-30. PMID: 11404275.
    Citations: 3     Fields:    Translation:Animals
  79. Kakinuma Y, Miyauchi T, Yuki K, Murakoshi N, Goto K, Yamaguchi I. Novel molecular mechanism of increased myocardial endothelin-1 expression in the failing heart involving the transcriptional factor hypoxia-inducible factor-1alpha induced for impaired myocardial energy metabolism. Circulation. 2001 May 15; 103(19):2387-94. PMID: 11352889.
    Citations: 16     Fields:    Translation:AnimalsCells
  80. Murakoshi N, Miyauchi T, Kakinuma Y, Yuki K, Goto K, Yamaguchi I. Impairment of cardiac energy metabolism in vivo causes hemodynamic abnormality and increases cardiac expression of preproendothelin-1 mRNA. J Cardiovasc Pharmacol. 2000 Nov; 36(5 Suppl 1):S128-31. PMID: 11078357.
    Citations: 1     Fields:    Translation:Animals
  81. Yuki K, Miyauchi T, Kakinuma Y, Murakoshi N, Suzuki T, Hayashi J, Goto K, Yamaguchi I. Mitochondrial dysfunction increases expression of endothelin-1 and induces apoptosis through caspase-3 activation in rat cardiomyocytes in vitro. J Cardiovasc Pharmacol. 2000 Nov; 36(5 Suppl 1):S205-8. PMID: 11078378.
    Citations: 2     Fields:    Translation:AnimalsCells
  82. Kakinuma Y, Miyauchi T, Yuki K, Murakoshi N, Goto K, Yamaguchi I. Mitochondrial dysfunction of cardiomyocytes causing impairment of cellular energy metabolism induces apoptosis, and concomitant increase in cardiac endothelin-1 expression. J Cardiovasc Pharmacol. 2000 Nov; 36(5 Suppl 1):S201-4. PMID: 11078377.
    Citations: 5     Fields:    Translation:AnimalsCells
  83. Iemitsu M, Miyauchi T, Maeda S, Yuki K, Kobayashi T, Kumagai Y, Shimojo N, Yamaguchi I, Matsuda M. Intense exercise causes decrease in expression of both endothelial NO synthase and tissue NOx level in hearts. . 2000 Sep; 279(3):R951-9. PMID: 10956253.
    Citations: 4     Fields:    Translation:Animals
  84. Pi J, Kumagai Y, Sun G, Yamauchi H, Yoshida T, Iso H, Endo A, Yu L, Yuki K, Miyauchi T, Shimojo N. Decreased serum concentrations of nitric oxide metabolites among Chinese in an endemic area of chronic arsenic poisoning in inner Mongolia. Free Radic Biol Med. 2000 Apr 01; 28(7):1137-42. PMID: 10832076.
    Citations: 28     Fields:    Translation:Humans
  85. Nagai S, Abe S, Sato T, Hozawa K, Yuki K, Hanashima K, Tomoike H. Ultrasonic assessment of vascular complications in coronary angiography and angioplasty after transradial approach. Am J Cardiol. 1999 Jan 15; 83(2):180-6. PMID: 10073818.
    Citations: 24     Fields:    Translation:HumansCTClinical Trials
  86. Kakinuma Y, Miyauchi T, Kobayashi T, Yuki K, Maeda S, Sakai S, Goto K, Yamaguchi I. Myocardial expression of endothelin-2 is altered reciprocally to that of endothelin-1 during ischemia of cardiomyocytes in vitro and during heart failure in vivo. Life Sci. 1999; 65(16):1671-83. PMID: 10573185.
    Citations: 3     Fields:    Translation:AnimalsCells
  87. Naito H, Miyoshi A, Nakatsuka M, Yuki K, Yamada H, Kobayashi Y, Tanimoto Y. [A case of unruptured aneurysm of the sinus of Valsalva producing a right ventricular outflow obstruction]. Kokyu To Junkan. 1985 Apr; 33(4):581-5. PMID: 4012087.
    Citations:    Fields:    Translation:Humans
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.