Harvard Catalyst Profiles

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Joji Fujisaki, Ph.D., M.D.

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Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01DK121889 (FUJISAKI, JOJI) Apr 1, 2020 - Jan 31, 2024
    NIH
    Identification of unique nitric oxide-expressing hematopoietic stem cells and their special vascular niche
    Role: Principal Investigator
  2. R01HL145154 (FUJISAKI, JOJI) Aug 15, 2019 - May 31, 2023
    NIH
    Roles and therapeutic potential of CD150high niche-associated regulatory T cells in bone marrow injury and engraftment
    Role: Principal Investigator
  3. R01HL129506 (FUJISAKI, JOJI) Jul 1, 2016 - Mar 31, 2021
    NIH
    Immune privilege of the hematopoieitic stem cell niche
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Kakiuchi M, Hirata Y, Robson SC, Fujisaki J. Transfer of stem cell niche-residential regulatory T cells prevents post-irradiation bone marrow injury. Haematologica. 2021 03 01; 106(3):891-893. PMID: 32554561.
    Citations:    Fields:    Translation:Cells
  2. Kakiuchi M, Hirata Y, Robson SC, Fujisaki J. Paradoxical Regulation of Allogeneic Bone Marrow Engraftment and Immune Privilege by Mesenchymal Cells and Adenosine. Transplant Cell Ther. 2021 Jan; 27(1):92.e1-92.e5. PMID: 32961376.
    Citations: 1     
  3. Hirata Y, Kakiuchi M, Robson SC, Fujisaki J. CD150high CD4 T cells and CD150high regulatory T cells regulate hematopoietic stem cell quiescence via CD73. Haematologica. 2019 06; 104(6):1136-1142. PMID: 30545927.
    Citations: 5     Fields:    Translation:AnimalsCells
  4. Hirata Y, Furuhashi K, Ishii H, Li HW, Pinho S, Ding L, Robson SC, Frenette PS, Fujisaki J. CD150high Bone Marrow Tregs Maintain Hematopoietic Stem Cell Quiescence and Immune Privilege via Adenosine. Cell Stem Cell. 2018 03 01; 22(3):445-453.e5. PMID: 29456159.
    Citations: 51     Fields:    Translation:AnimalsCells
  5. Sawai CM, Babovic S, Upadhaya S, Knapp DJHF, Lavin Y, Lau CM, Goloborodko A, Feng J, Fujisaki J, Ding L, Mirny LA, Merad M, Eaves CJ, Reizis B. Hematopoietic Stem Cells Are the Major Source of Multilineage Hematopoiesis in Adult Animals. Immunity. 2016 09 20; 45(3):597-609. PMID: 27590115.
    Citations: 109     Fields:    Translation:AnimalsCells
  6. Hirata Y, Li HW, Takahashi K, Ishii H, Sykes M, Fujisaki J. MHC Class I Expression by Donor Hematopoietic Stem Cells Is Required to Prevent NK Cell Attack in Allogeneic, but Not Syngeneic Recipient Mice. PLoS One. 2015; 10(11):e0141785. PMID: 26544200.
    Citations: 1     Fields:    Translation:AnimalsCells
  7. Carlson AL, Fujisaki J, Wu J, Runnels JM, Turcotte R, Spencer JA, Celso CL, Scadden DT, Strom TB, Lin CP. Tracking single cells in live animals using a photoconvertible near-infrared cell membrane label. PLoS One. 2013; 8(8):e69257. PMID: 23990881.
    Citations: 18     Fields:    Translation:AnimalsCells
  8. Miller PG, Al-Shahrour F, Hartwell KA, Chu LP, Järås M, Puram RV, Puissant A, Callahan KP, Ashton J, McConkey ME, Poveromo LP, Cowley GS, Kharas MG, Labelle M, Shterental S, Fujisaki J, Silberstein L, Alexe G, Al-Hajj MA, Shelton CA, Armstrong SA, Root DE, Scadden DT, Hynes RO, Mukherjee S, Stegmaier K, Jordan CT, Ebert BL. In Vivo RNAi screening identifies a leukemia-specific dependence on integrin beta 3 signaling. Cancer Cell. 2013 Jul 08; 24(1):45-58. PMID: 23770013.
    Citations: 74     Fields:    Translation:HumansAnimalsCells
  9. Park D, Spencer JA, Koh BI, Kobayashi T, Fujisaki J, Clemens TL, Lin CP, Kronenberg HM, Scadden DT. Endogenous bone marrow MSCs are dynamic, fate-restricted participants in bone maintenance and regeneration. Cell Stem Cell. 2012 Mar 02; 10(3):259-72. PMID: 22385654.
    Citations: 247     Fields:    Translation:HumansAnimalsCells
  10. Fujisaki J, Wu J, Carlson AL, Silberstein L, Putheti P, Larocca R, Gao W, Saito TI, Lo Celso C, Tsuyuzaki H, Sato T, Côté D, Sykes M, Strom TB, Scadden DT, Lin CP. In vivo imaging of Treg cells providing immune privilege to the haematopoietic stem-cell niche. Nature. 2011 Jun 08; 474(7350):216-9. PMID: 21654805.
    Citations: 211     Fields:    Translation:HumansAnimalsCells
  11. Saito TI, Fujisaki J, Carlson AL, Lin CP, Sykes M. Persistence of donor-derived protein in host myeloid cells after induced rejection of engrafted allogeneic bone marrow cells. Exp Hematol. 2010 Apr; 38(4):333-9. PMID: 20167247.
    Citations:    Fields:    Translation:AnimalsCells
  12. Lo Celso C, Fleming HE, Wu JW, Zhao CX, Miake-Lye S, Fujisaki J, Côté D, Rowe DW, Lin CP, Scadden DT. Live-animal tracking of individual haematopoietic stem/progenitor cells in their niche. Nature. 2009 Jan 01; 457(7225):92-6. PMID: 19052546.
    Citations: 354     Fields:    Translation:AnimalsCells
  13. Fujisaki J, Tanaka T, Kato J, Saito T, Yano K, Shimizu Y, Sada T, Kitazume K, Fujita A, Kira Y. Primary cardiac lymphoma presenting clinically as restrictive cardiomyopathy. Circ J. 2005 Feb; 69(2):249-52. PMID: 15671623.
    Citations: 4     Fields:    Translation:Humans
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.