Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Robert Edgardo Gerszten, M.D.

Title
Institution
Department
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Research
research activities and funding
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
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  1. R01HL157530 (YEH, ROBERT) Apr 1, 2021 - Mar 31, 2025
    NIH
    A Multi-Dimensional Linked Registry to Identify Biological, Clinical, Health System, and Socioeconomic Risk Factors for COVID-19-Related Cardiovascular Events
    Role: Co-Principal Investigator
  2. R01NR019628 (GERSZTEN, ROBERT E) Mar 3, 2021 - Dec 31, 2025
    NIH
    Biochemical profiling to identify cardiometabolic responsiveness to an endurance exercise intervention
    Role: Principal Investigator
  3. R01HL144483 (PSATY, BRUCE M) Jul 15, 2019 - Jun 30, 2023
    NIH
    Plasma proteomics in CHS and population biology
    Role: Co-Principal Investigator
  4. R01AG063507 (RAMACHANDRAN, VASAN S) Jul 1, 2019 - Apr 30, 2024
    NIH/NIA
    Plasma Proteome and Risk of Alzheimer Dementia and Related Endophenotypes in the Framingham Study
    Role: Co-Principal Investigator
  5. RF1AG063507 (RAMACHANDRAN, VASAN S) Jul 1, 2019 - Mar 31, 2024
    NIH
    Plasma Proteome and Risk of Alzheimer Dementia and Related Endophenotypes in the Framingham Study
    Role: Co-Principal Investigator

Bibliographic
selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Chen ZZ, Gao Y, Keyes MJ, Deng S, Mi M, Farrell LA, Shen D, Tahir UA, Cruz DE, Ngo D, Benson MD, Robbins JM, Correa A, Wilson JG, Gerszten RE. Protein Markers of Diabetes Discovered in an African American Cohort. Diabetes. 2023 Apr 01; 72(4):532-543. PMID: 36630488.
    Citations:    Fields:    
  2. Wang S, Yazawa E, Keating E, Mazumdar N, Hauschild A, Ma Q, Wu H, Xu Y, Shi X, Strathdee D, Gerszten RE, Schlame M, Pu WT. Genetic modifiers modulate phenotypic expression of tafazzin deficiency in a mouse model of Barth syndrome. Hum Mol Genet. 2023 Mar 14. PMID: 36917259.
    Citations:    Fields:    
  3. Cronjé HT, Mi MY, Austin TR, Biggs ML, Siscovick DS, Lemaitre RN, Psaty BM, Tracy RP, Djoussé L, Kizer JR, Ix JH, Rao P, Robbins JM, Barber JL, Sarzynski MA, Clish CB, Bouchard C, Mukamal KJ, Gerszten RE, Jensen MK. Plasma proteomic risk markers of incident type 2 diabetes reflect physiologically distinct components of glucose-insulin homeostasis. Diabetes. 2023 Feb 07. PMID: 36749929.
    Citations:    Fields:    
  4. Bebarta VS, Shi X, Zheng S, Hendry-Hofer TB, Severance CC, Behymer MM, Boss GR, Mahon S, Brenner M, Knipp GT, Davisson VJ, Peterson RT, MacRae CA, Rutter J, Gerszten RE, Nath AK. Intramuscular administration of glyoxylate rescues swine from lethal cyanide poisoning and ameliorates the biochemical sequalae of cyanide intoxication. Toxicol Sci. 2023 01 31; 191(1):90-105. PMID: 36326479; PMCID: PMC9887668.
    Citations:    Fields:    Translation:Animals
  5. Mi MY, Whitlock M, Shi X, Farrell LA, Bhambhani VM, Quadir J, Blatnik M, Wald KP, Tierney B, Kim A, Loudon P, Chen ZZ, Correa A, Gao Y, Carson AP, Bertoni AG, Roth Flach RJ, Gerszten RE. Mixed meal tolerance testing highlights in diabetes altered branched-chain ketoacid metabolism and pathways associated with all-cause mortality. Am J Clin Nutr. 2023 Mar; 117(3):529-539. PMID: 36811472.
    Citations:    Fields:    Translation:Humans
  6. Liu J, Lane S, Lall R, Russo M, Farrell L, Debreli Coskun M, Curtin C, Araujo-Gutierrez R, Scherrer-Crosbie M, Trachtenberg BH, Kim J, Tolosano E, Ghigo A, Gerszten RE, Asnani A. Circulating hemopexin modulates anthracycline cardiac toxicity in patients and in mice. Sci Adv. 2022 12 23; 8(51):eadc9245. PMID: 36563141; PMCID: PMC9788780.
    Citations:    Fields:    Translation:Animals
  7. Zhang Y, Ngo D, Yu B, Shah NA, Chen H, Ramos AR, Zee PC, Tracy R, Durda P, Kaplan R, Daviglus ML, Rich SS, Rotter JI, Cai J, Clish C, Gerszten R, Kristal BS, Gharib SA, Redline S, Sofer T. Development and validation of a metabolite index for obstructive sleep apnea across race/ethnicities. Sci Rep. 2022 12 16; 12(1):21805. PMID: 36526671; PMCID: PMC9758170.
    Citations:    Fields:    Translation:Humans
  8. Bersell KR, Yang T, Mosley JD, Glazer AM, Hale AT, Kryshtal DO, Kim K, Steimle JD, Brown JD, Salem JE, Campbell CC, Hong CC, Wells QS, Johnson AN, Short L, Blair MA, Behr ER, Petropoulou E, Jamshidi Y, Benson MD, Keyes MJ, Ngo D, Vasan RS, Yang Q, Gerszten RE, Shaffer C, Parikh S, Sheng Q, Kannankeril PJ, Moskowitz IP, York JD, Wang TJ, Knollmann BC, Roden DM. Transcriptional Dysregulation Underlies Both Monogenic Arrhythmia Syndrome and Common Modifiers of Cardiac Repolarization. Circulation. 2023 Mar 07; 147(10):824-840. PMID: 36524479; PMCID: PMC9992308.
    Citations:    Fields:    Translation:HumansAnimalsCells
  9. Kaserman JE, Werder RB, Wang F, Matte T, Higgins MI, Dodge M, Lindstrom-Vautrin J, Bawa P, Hinds A, Bullitt E, Caballero IS, Shi X, Gerszten RE, Brunetti-Pierri N, Liesa M, Villacorta-Martin C, Hollenberg AN, Kotton DN, Wilson AA. Human iPSC-hepatocyte modeling of alpha-1 antitrypsin heterozygosity reveals metabolic dysregulation and cellular heterogeneity. Cell Rep. 2022 12 06; 41(10):111775. PMID: 36476855; PMCID: PMC9780780.
    Citations: 1     Fields:    Translation:HumansCells
  10. McClain KM, Sampson JN, Petrick JL, Mazzilli KM, Gerszten RE, Clish CB, Purdue MP, Lipworth L, Moore SC. Metabolomic Analysis of Renal Cell Carcinoma in the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial. Metabolites. 2022 Nov 29; 12(12). PMID: 36557227; PMCID: PMC9785244.
    Citations:    
  11. Bhave VM, Ament Z, Patki A, Gao Y, Kijpaisalratana N, Guo B, Chaudhary NS, Guarniz AG, Gerszten R, Correa A, Cushman M, Judd S, Irvin MR, Kimberly WT. Plasma Metabolites Link Dietary Patterns to Stroke Risk. Ann Neurol. 2023 03; 93(3):500-510. PMID: 36373825; PMCID: PMC9974740.
    Citations:    Fields:    Translation:Humans
  12. Regan JA, Truby LK, Tahir UA, Katz DH, Nguyen M, Kwee LC, Deng S, Wilson JG, Mentz RJ, Kraus WE, Hernandez AF, Gerszten RE, Peterson ED, Holman RR, Shah SH. Protein biomarkers of cardiac remodeling and inflammation associated with HFpEF and incident events. Sci Rep. 2022 11 22; 12(1):20072. PMID: 36418363; PMCID: PMC9684116.
    Citations:    Fields:    Translation:Humans
  13. Liu X, Pan S, Xanthakis V, Vasan RS, Psaty BM, Austin TR, Newman AB, Sanders JL, Wu C, Tracy RP, Gerszten RE, Odden MC. Plasma proteomic signature of decline in gait speed and grip strength. Aging Cell. 2022 Dec; 21(12):e13736. PMID: 36333824; PMCID: PMC9741503.
    Citations: 2     Fields:    Translation:Humans
  14. Chow LS, Gerszten RE, Taylor JM, Pedersen BK, van Praag H, Trappe S, Febbraio MA, Galis ZS, Gao Y, Haus JM, Lanza IR, Lavie CJ, Lee CH, Lucia A, Moro C, Pandey A, Robbins JM, Stanford KI, Thackray AE, Villeda S, Watt MJ, Xia A, Zierath JR, Goodpaster BH, Snyder M. Reply to 'Lactate as a major myokine and exerkine'. Nat Rev Endocrinol. 2022 11; 18(11):713. PMID: 35915255.
    Citations: 1     Fields:    Translation:HumansCells
  15. Chen ZZ, Pacheco JA, Gao Y, Deng S, Peterson B, Shi X, Zheng S, Tahir UA, Katz DH, Cruz DE, Ngo D, Benson MD, Robbins JM, Guo X, Del Rocio Sevilla Gonzalez M, Manning A, Correa A, Meigs JB, Taylor KD, Rich SS, Goodarzi MO, Rotter JI, Wilson JG, Clish CB, Gerszten RE. Nontargeted and Targeted Metabolomic Profiling Reveals Novel Metabolite Biomarkers of Incident Diabetes in African Americans. Diabetes. 2022 11 01; 71(11):2426-2437. PMID: 35998269; PMCID: PMC9630088.
    Citations:    Fields:    Translation:Humans
  16. Gonzalez Izundegui D, Miller PE, Shah RV, Clish CB, Walker ME, Mitchell GF, Gerszten RE, Larson MG, Vasan RS, Nayor M. Response of circulating metabolites to an oral glucose challenge and risk of cardiovascular disease and mortality in the community. Cardiovasc Diabetol. 2022 10 15; 21(1):213. PMID: 36243866; PMCID: PMC9568897.
    Citations:    Fields:    Translation:Humans
  17. Kahn D, Macias E, Zarini S, Garfield A, Zemski Berry K, MacLean P, Gerszten RE, Libby A, Solt C, Schoen J, Bergman BC. Exploring Visceral and Subcutaneous Adipose Tissue Secretomes in Human Obesity: Implications for Metabolic Disease. Endocrinology. 2022 10 11; 163(11). PMID: 36036084; PMCID: PMC9761573.
    Citations: 2     Fields:    Translation:HumansAnimals
  18. Pan XF, Chen ZZ, Wang TJ, Shu X, Cai H, Cai Q, Clish CB, Shi X, Zheng W, Gerszten RE, Shu XO, Yu D. Plasma metabolomic signatures of obesity and risk of type 2 diabetes. Obesity (Silver Spring). 2022 11; 30(11):2294-2306. PMID: 36161775; PMCID: PMC9633360.
    Citations:    Fields:    Translation:Humans
  19. Hu J, Yao J, Deng S, Balasubramanian R, Jiménez MC, Li J, Guo X, Cruz DE, Gao Y, Huang T, Zeleznik OA, Ngo D, Liu S, Rosal MC, Nassir R, Paynter NP, Albert CM, Tracy RP, Durda P, Liu Y, Taylor KD, Johnson WC, Sun Q, Rimm EB, Eliassen AH, Rich SS, Rotter JI, Gerszten RE, Clish CB, Rexrode KM. Differences in Metabolomic Profiles Between Black and White Women and Risk of Coronary Heart Disease: an Observational Study of Women From Four US Cohorts. Circ Res. 2022 09 16; 131(7):601-615. PMID: 36052690; PMCID: PMC9473718.
    Citations: 3     Fields:    Translation:Humans
  20. Paranjpe MD, Chaffin M, Zahid S, Ritchie S, Rotter JI, Rich SS, Gerszten R, Guo X, Heckbert S, Tracy R, Danesh J, Lander ES, Inouye M, Kathiresan S, Butterworth AS, Khera AV. Neurocognitive trajectory and proteomic signature of inherited risk for Alzheimer's disease. PLoS Genet. 2022 09; 18(9):e1010294. PMID: 36048760; PMCID: PMC9436054.
    Citations:    Fields:    Translation:Humans
  21. Zheng H, Gerszten RE, Corey KE. Visualizing biomarkers and their association with clinical outcomes: A machine learning approach. Comput Biol Med. 2022 10; 149:106005. PMID: 36067630.
    Citations:    Fields:    Translation:Humans
  22. Tahir UA, Katz DH, Avila-Pachecho J, Bick AG, Pampana A, Robbins JM, Yu Z, Chen ZZ, Benson MD, Cruz DE, Ngo D, Deng S, Shi X, Zheng S, Eisman AS, Farrell L, Hall ME, Correa A, Tracy RP, Durda P, Taylor KD, Liu Y, Johnson WC, Guo X, Yao J, Chen YI, Manichaikul AW, Ruberg FL, Blaner WS, Jain D, Bouchard C, Sarzynski MA, Rich SS, Rotter JI, Wang TJ, Wilson JG, Clish CB, Natarajan P, Gerszten RE. Whole Genome Association Study of the Plasma Metabolome Identifies Metabolites Linked to Cardiometabolic Disease in Black Individuals. Nat Commun. 2022 08 22; 13(1):4923. PMID: 35995766; PMCID: PMC9395431.
    Citations: 1     Fields:    Translation:Humans
  23. Katz DH, Robbins JM, Deng S, Tahir UA, Bick AG, Pampana A, Yu Z, Ngo D, Benson MD, Chen ZZ, Cruz DE, Shen D, Gao Y, Bouchard C, Sarzynski MA, Correa A, Natarajan P, Wilson JG, Gerszten RE. Proteomic profiling platforms head to head: Leveraging genetics and clinical traits to compare aptamer- and antibody-based methods. Sci Adv. 2022 08 19; 8(33):eabm5164. PMID: 35984888; PMCID: PMC9390994.
    Citations: 6     Fields:    Translation:Humans
  24. Kahn D, Macias E, Zarini S, Garfield A, Zemski Berry K, Gerszten R, Schoen J, Cree-Green M, Bergman BC. Quantifying the inflammatory secretome of human intermuscular adipose tissue. Physiol Rep. 2022 08; 10(16):e15424. PMID: 35980018; PMCID: PMC9387112.
    Citations:    Fields:    Translation:Humans
  25. Austin TR, McHugh CP, Brody JA, Bis JC, Sitlani CM, Bartz TM, Biggs ML, Bansal N, Buzkova P, Carr SA, deFilippi CR, Elkind MSV, Fink HA, Floyd JS, Fohner AE, Gerszten RE, Heckbert SR, Katz DH, Kizer JR, Lemaitre RN, Longstreth WT, McKnight B, Mei H, Mukamal KJ, Newman AB, Ngo D, Odden MC, Vasan RS, Shojaie A, Simon N, Smith GD, Davies NM, Siscovick DS, Sotoodehnia N, Tracy RP, Wiggins KL, Zheng J, Psaty BM. Proteomics and Population Biology in the Cardiovascular Health Study (CHS): design of a study with mentored access and active data sharing. Eur J Epidemiol. 2022 Jul; 37(7):755-765. PMID: 35790642; PMCID: PMC9255954.
    Citations: 1     Fields:    Translation:Humans
  26. Ooka T, Raita Y, Fujiogi M, Freishtat RJ, Gerszten RE, Mansbach JM, Zhu Z, Camargo CA, Hasegawa K. Proteomics endotyping of infants with severe bronchiolitis and risk of childhood asthma. Allergy. 2022 11; 77(11):3350-3361. PMID: 35620861; PMCID: PMC9617778.
    Citations: 1     Fields:    Translation: