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Gerszten, Robert
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Robert Edgardo Gerszten, M.D.
Title
Herman Dana Professor of Medicine
Institution
Beth Israel Deaconess Medical Center
Department
Medicine
Address
Beth Israel Deaconess Medical Center
330 Brookline Ave
Boston MA 02215
Fax
617/643-3451
research activities and funding
|
selected publications
|
Research
research activities and funding
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can
login
to make corrections and additions.
Most Recent
|
List All
R01HL157530
(YEH, ROBERT)
Apr 1, 2021 - Mar 31, 2025
NIH
A Multi-Dimensional Linked Registry to Identify Biological, Clinical, Health System, and Socioeconomic Risk Factors for COVID-19-Related Cardiovascular Events
Role: Co-Principal Investigator
R01NR019628
(GERSZTEN, ROBERT E)
Mar 3, 2021 - Dec 31, 2025
NIH
Biochemical profiling to identify cardiometabolic responsiveness to an endurance exercise intervention
Role: Principal Investigator
R01HL144483
(PSATY, BRUCE M)
Jul 15, 2019 - Jun 30, 2023
NIH
Plasma proteomics in CHS and population biology
Role: Co-Principal Investigator
R01AG063507
(RAMACHANDRAN, VASAN S)
Jul 1, 2019 - Apr 30, 2024
NIH/NIA
Plasma Proteome and Risk of Alzheimer Dementia and Related Endophenotypes in the Framingham Study
Role: Co-Principal Investigator
RF1AG063507
(RAMACHANDRAN, VASAN S)
Jul 1, 2019 - Mar 31, 2024
NIH
Plasma Proteome and Risk of Alzheimer Dementia and Related Endophenotypes in the Framingham Study
Role: Co-Principal Investigator
R01HL133870
(GERSZTEN, ROBERT E)
Apr 1, 2017 - Feb 28, 2021
NIH
Aptamer Proteomics of Cardiometabolic and Renal Traits in African Americans
Role: Co-Principal Investigator
U24DK112340
(GERSZTEN, ROBERT E)
Dec 14, 2016 - Nov 30, 2022
NIH
A Biochemical Roadmap of Exercise Signaling
Role: Co-Principal Investigator
R01HL132320
(GERSZTEN, ROBERT E)
Jul 1, 2016 - Apr 30, 2021
NIH
Proteomic Pathway Discovery in Cardiovascular Disease
Role: Principal Investigator
R01DK108159
(WANG, THOMAS J.)
Apr 1, 2016 - Mar 31, 2021
NIH
Metabolite profiles and the risk of diabetes in Asians
Role: Principal Investigator
U54NS079201
(MACRAE, CALUM A.)
Sep 30, 2012 - Aug 31, 2018
NIH
A Discovery and Development Pipeline for Cyanide Countermeasures
Role: Co-Principal Investigator
R24DK092158
(POLLAK, MARTIN R.)
Sep 19, 2011 - Aug 31, 2013
NIH
Clinical characterization of the APOL1-associated phenotype
Role: Co-Principal Investigator
U01HL107440
(COWAN, CHAD ALBERT)
Jul 5, 2011 - Jun 30, 2017
NIH
Integrating lipid genotyes and phenotypes in iPS derived hepatocytes/adipocytes
Role: Co-Principal Investigator
R01HL098280
(GERSZTEN, ROBERT E)
Mar 15, 2010 - Jan 31, 2016
NIH
Metabolomic Biomarkers of Early Myocardial Injury
Role: Principal Investigator
R01HL096738
(GERSZTEN, ROBERT E)
Aug 1, 2009 - Jun 30, 2014
NIH
Discovery & Application of Proteomics-Based Biomarkers of Early Myocardial Injury
Role: Co-Principal Investigator
R01DK081572
(GERSZTEN, ROBERT E)
Aug 1, 2008 - Aug 31, 2026
NIH
Metabolomic predictors of insulin resistance and diabetes
Role: Principal Investigator
U01HL081341
(GERSZTEN, ROBERT E)
Aug 25, 2005 - Jun 30, 2009
NIH
Novel Markers: Pathways, Prognosis, &Pharmacoproteomics
Role: Principal Investigator
R01HL072872
(GERSZTEN, ROBERT E)
Sep 25, 2002 - Jul 31, 2007
NIH
Clinical Evaluation of Novel Markers of MI
Role: Principal Investigator
K02HL067768
(GERSZTEN, ROBERT E)
Sep 1, 2001 - Aug 31, 2006
NIH
Chemokine Signaling in Monocyte Recruitment In Vivo
Role: Principal Investigator
R01HL065584
(GERSZTEN, ROBERT E)
Jul 1, 2000 - Jan 31, 2011
NIH
Role of ILK in Leukocyte Recruitment
Role: Principal Investigator
K08HL003348
(GERSZTEN, ROBERT E)
Aug 1, 1996 - Jul 31, 2001
NIH
MOLECULAR SIGNALS IN MONOCYTE RECRUITMENT
Role: Principal Investigator
T32HL007208
(ROSENZWEIG, ANTHONY)
Jul 1, 1976 - Jun 30, 2023
NIH
Integrated, Multidisciplinary Training in Cardiovascular Research
Role: Co-Principal Investigator
Bibliographic
selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can
login
to make corrections and additions.
Newest
|
Oldest
|
Most Cited
|
Most Discussed
|
Timeline
|
Field Summary
|
Plain Text
PMC Citations
indicate the number of times the publication was cited by articles in PubMed Central, and the
Altmetric
score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.)
Fields
are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication.
Translation
tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
Chen ZZ
, Gao Y, Keyes MJ, Deng S,
Mi M
, Farrell LA, Shen D,
Tahir UA
,
Cruz DE
, Ngo D,
Benson MD
,
Robbins JM
, Correa A, Wilson JG,
Gerszten RE
. Protein Markers of Diabetes Discovered in an African American Cohort. Diabetes. 2023 Apr 01; 72(4):532-543.
PMID:
36630488
.
Citations:
Fields:
End
Endocrinology
Wang S,
Yazawa E
, Keating E, Mazumdar N, Hauschild A, Ma Q, Wu H, Xu Y, Shi X, Strathdee D,
Gerszten RE
, Schlame M,
Pu WT
. Genetic modifiers modulate phenotypic expression of tafazzin deficiency in a mouse model of Barth syndrome. Hum Mol Genet. 2023 Mar 14.
PMID:
36917259
.
Citations:
Fields:
Gen
Genetics
Mol
Molecular Biology
Cronjé HT,
Mi MY
, Austin TR, Biggs ML, Siscovick DS, Lemaitre RN, Psaty BM, Tracy RP, Djoussé L, Kizer JR, Ix JH,
Rao P
,
Robbins JM
,
Barber JL
, Sarzynski MA, Clish CB, Bouchard C,
Mukamal KJ
,
Gerszten RE
,
Jensen MK
. Plasma proteomic risk markers of incident type 2 diabetes reflect physiologically distinct components of glucose-insulin homeostasis. Diabetes. 2023 Feb 07.
PMID:
36749929
.
Citations:
Fields:
End
Endocrinology
Bebarta VS, Shi X, Zheng S, Hendry-Hofer TB, Severance CC, Behymer MM, Boss GR, Mahon S, Brenner M, Knipp GT, Davisson VJ, Peterson RT,
MacRae CA
, Rutter J,
Gerszten RE
, Nath AK. Intramuscular administration of glyoxylate rescues swine from lethal cyanide poisoning and ameliorates the biochemical sequalae of cyanide intoxication. Toxicol Sci. 2023 01 31; 191(1):90-105.
PMID:
36326479
; PMCID:
PMC9887668
.
Citations:
Fields:
Tox
Toxicology
Translation:
Animals
Mi MY
, Whitlock M, Shi X, Farrell LA, Bhambhani VM, Quadir J, Blatnik M, Wald KP, Tierney B, Kim A, Loudon P,
Chen ZZ
, Correa A, Gao Y, Carson AP, Bertoni AG, Roth Flach RJ,
Gerszten RE
. Mixed meal tolerance testing highlights in diabetes altered branched-chain ketoacid metabolism and pathways associated with all-cause mortality. Am J Clin Nutr. 2023 Mar; 117(3):529-539.
PMID:
36811472
.
Citations:
Fields:
Nut
Nutritional Sciences
Translation:
Humans
Liu J, Lane S, Lall R, Russo M, Farrell L, Debreli Coskun M, Curtin C, Araujo-Gutierrez R, Scherrer-Crosbie M, Trachtenberg BH, Kim J, Tolosano E, Ghigo A,
Gerszten RE
,
Asnani A
. Circulating hemopexin modulates anthracycline cardiac toxicity in patients and in mice. Sci Adv. 2022 12 23; 8(51):eadc9245.
PMID:
36563141
; PMCID:
PMC9788780
.
Citations:
Fields:
Sci
Science
Translation:
Animals
Zhang Y, Ngo D, Yu B, Shah NA, Chen H, Ramos AR, Zee PC, Tracy R, Durda P, Kaplan R, Daviglus ML, Rich SS, Rotter JI, Cai J, Clish C,
Gerszten R
,
Kristal BS
, Gharib SA,
Redline S
,
Sofer T
. Development and validation of a metabolite index for obstructive sleep apnea across race/ethnicities. Sci Rep. 2022 12 16; 12(1):21805.
PMID:
36526671
; PMCID:
PMC9758170
.
Citations:
Fields:
Sci
Science
Translation:
Humans
Bersell KR
, Yang T, Mosley JD, Glazer AM, Hale AT, Kryshtal DO, Kim K, Steimle JD, Brown JD, Salem JE, Campbell CC, Hong CC, Wells QS, Johnson AN, Short L, Blair MA, Behr ER, Petropoulou E, Jamshidi Y, Benson MD, Keyes MJ, Ngo D, Vasan RS, Yang Q,
Gerszten RE
, Shaffer C, Parikh S, Sheng Q, Kannankeril PJ, Moskowitz IP, York JD, Wang TJ, Knollmann BC, Roden DM. Transcriptional Dysregulation Underlies Both Monogenic Arrhythmia Syndrome and Common Modifiers of Cardiac Repolarization. Circulation. 2023 Mar 07; 147(10):824-840.
PMID:
36524479
; PMCID:
PMC9992308
.
Citations:
Fields:
Car
Cardiology
Vas
Vascular Diseases
Translation:
Humans
Animals
Cells
Kaserman JE, Werder RB, Wang F, Matte T, Higgins MI, Dodge M, Lindstrom-Vautrin J, Bawa P, Hinds A, Bullitt E, Caballero IS, Shi X,
Gerszten RE
, Brunetti-Pierri N, Liesa M, Villacorta-Martin C, Hollenberg AN, Kotton DN, Wilson AA. Human iPSC-hepatocyte modeling of alpha-1 antitrypsin heterozygosity reveals metabolic dysregulation and cellular heterogeneity. Cell Rep. 2022 12 06; 41(10):111775.
PMID:
36476855
; PMCID:
PMC9780780
.
Citations:
1
Fields:
Cel
Cell Biology
Mol
Molecular Biology
Translation:
Humans
Cells
McClain KM, Sampson JN, Petrick JL, Mazzilli KM,
Gerszten RE
, Clish CB, Purdue MP, Lipworth L, Moore SC. Metabolomic Analysis of Renal Cell Carcinoma in the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial. Metabolites. 2022 Nov 29; 12(12).
PMID:
36557227
; PMCID:
PMC9785244
.
Citations:
Bhave VM,
Ament Z
, Patki A, Gao Y, Kijpaisalratana N, Guo B, Chaudhary NS, Guarniz AG,
Gerszten R
, Correa A, Cushman M, Judd S, Irvin MR,
Kimberly WT
. Plasma Metabolites Link Dietary Patterns to Stroke Risk. Ann Neurol. 2023 03; 93(3):500-510.
PMID:
36373825
; PMCID:
PMC9974740
.
Citations:
Fields:
Neu
Neurology
Translation:
Humans
Regan JA, Truby LK,
Tahir UA
, Katz DH, Nguyen M, Kwee LC, Deng S, Wilson JG, Mentz RJ, Kraus WE, Hernandez AF,
Gerszten RE
, Peterson ED, Holman RR, Shah SH. Protein biomarkers of cardiac remodeling and inflammation associated with HFpEF and incident events. Sci Rep. 2022 11 22; 12(1):20072.
PMID:
36418363
; PMCID:
PMC9684116
.
Citations:
Fields:
Sci
Science
Translation:
Humans
Liu X, Pan S, Xanthakis V, Vasan RS, Psaty BM, Austin TR, Newman AB, Sanders JL, Wu C, Tracy RP,
Gerszten RE
, Odden MC. Plasma proteomic signature of decline in gait speed and grip strength. Aging Cell. 2022 Dec; 21(12):e13736.
PMID:
36333824
; PMCID:
PMC9741503
.
Citations:
2
Fields:
Cel
Cell Biology
Translation:
Humans
Chow LS,
Gerszten RE
, Taylor JM, Pedersen BK, van Praag H, Trappe S, Febbraio MA, Galis ZS, Gao Y, Haus JM, Lanza IR, Lavie CJ, Lee CH, Lucia A, Moro C, Pandey A,
Robbins JM
, Stanford KI, Thackray AE, Villeda S, Watt MJ, Xia A, Zierath JR, Goodpaster BH, Snyder M. Reply to 'Lactate as a major myokine and exerkine'. Nat Rev Endocrinol. 2022 11; 18(11):713.
PMID:
35915255
.
Citations:
1
Fields:
End
Endocrinology
Translation:
Humans
Cells
Chen ZZ
, Pacheco JA, Gao Y, Deng S, Peterson B, Shi X, Zheng S,
Tahir UA
, Katz DH,
Cruz DE
, Ngo D,
Benson MD
,
Robbins JM
, Guo X, Del Rocio Sevilla Gonzalez M,
Manning A
, Correa A,
Meigs JB
, Taylor KD, Rich SS, Goodarzi MO, Rotter JI, Wilson JG, Clish CB,
Gerszten RE
. Nontargeted and Targeted Metabolomic Profiling Reveals Novel Metabolite Biomarkers of Incident Diabetes in African Americans. Diabetes. 2022 11 01; 71(11):2426-2437.
PMID:
35998269
; PMCID:
PMC9630088
.
Citations:
Fields:
End
Endocrinology
Translation:
Humans
Gonzalez Izundegui D, Miller PE, Shah RV, Clish CB, Walker ME, Mitchell GF,
Gerszten RE
, Larson MG, Vasan RS, Nayor M. Response of circulating metabolites to an oral glucose challenge and risk of cardiovascular disease and mortality in the community. Cardiovasc Diabetol. 2022 10 15; 21(1):213.
PMID:
36243866
; PMCID:
PMC9568897
.
Citations:
Fields:
Car
Cardiology
End
Endocrinology
Vas
Vascular Diseases
Translation:
Humans
Kahn D, Macias E, Zarini S, Garfield A, Zemski Berry K, MacLean P,
Gerszten RE
, Libby A, Solt C, Schoen J, Bergman BC. Exploring Visceral and Subcutaneous Adipose Tissue Secretomes in Human Obesity: Implications for Metabolic Disease. Endocrinology. 2022 10 11; 163(11).
PMID:
36036084
; PMCID:
PMC9761573
.
Citations:
2
Fields:
End
Endocrinology
Translation:
Humans
Animals
Pan XF,
Chen ZZ
, Wang TJ, Shu X, Cai H, Cai Q, Clish CB, Shi X, Zheng W,
Gerszten RE
, Shu XO, Yu D. Plasma metabolomic signatures of obesity and risk of type 2 diabetes. Obesity (Silver Spring). 2022 11; 30(11):2294-2306.
PMID:
36161775
; PMCID:
PMC9633360
.
Citations:
Fields:
Met
Metabolism
Nut
Nutritional Sciences
Phy
Physiology
Translation:
Humans
Hu J
, Yao J, Deng S, Balasubramanian R, Jiménez MC, Li J, Guo X,
Cruz DE
, Gao Y,
Huang T
,
Zeleznik OA
, Ngo D, Liu S, Rosal MC, Nassir R, Paynter NP, Albert CM, Tracy RP, Durda P, Liu Y, Taylor KD, Johnson WC, Sun Q,
Rimm EB
,
Eliassen AH
, Rich SS, Rotter JI,
Gerszten RE
, Clish CB,
Rexrode KM
. Differences in Metabolomic Profiles Between Black and White Women and Risk of Coronary Heart Disease: an Observational Study of Women From Four US Cohorts. Circ Res. 2022 09 16; 131(7):601-615.
PMID:
36052690
; PMCID:
PMC9473718
.
Citations:
3
Fields:
Car
Cardiology
Vas
Vascular Diseases
Translation:
Humans
Paranjpe MD, Chaffin M, Zahid S, Ritchie S, Rotter JI, Rich SS,
Gerszten R
, Guo X, Heckbert S, Tracy R, Danesh J,
Lander ES
, Inouye M,
Kathiresan S
, Butterworth AS,
Khera AV
. Neurocognitive trajectory and proteomic signature of inherited risk for Alzheimer's disease. PLoS Genet. 2022 09; 18(9):e1010294.
PMID:
36048760
; PMCID:
PMC9436054
.
Citations:
Fields:
Gen
Genetics
Translation:
Humans
Zheng H,
Gerszten RE
,
Corey KE
. Visualizing biomarkers and their association with clinical outcomes: A machine learning approach. Comput Biol Med. 2022 10; 149:106005.
PMID:
36067630
.
Citations:
Fields:
Bio
Biology
Med
Medical Informatics
Med
Medicine (General)
Translation:
Humans
Tahir UA
, Katz DH, Avila-Pachecho J, Bick AG, Pampana A,
Robbins JM
, Yu Z,
Chen ZZ
,
Benson MD
,
Cruz DE
, Ngo D, Deng S, Shi X, Zheng S, Eisman AS, Farrell L, Hall ME, Correa A, Tracy RP, Durda P, Taylor KD, Liu Y, Johnson WC, Guo X, Yao J, Chen YI, Manichaikul AW, Ruberg FL, Blaner WS, Jain D, Bouchard C, Sarzynski MA, Rich SS, Rotter JI, Wang TJ, Wilson JG, Clish CB,
Natarajan P
,
Gerszten RE
. Whole Genome Association Study of the Plasma Metabolome Identifies Metabolites Linked to Cardiometabolic Disease in Black Individuals. Nat Commun. 2022 08 22; 13(1):4923.
PMID:
35995766
; PMCID:
PMC9395431
.
Citations:
1
Fields:
Bio
Biology
Sci
Science
Translation:
Humans
Katz DH,
Robbins JM
, Deng S,
Tahir UA
, Bick AG, Pampana A, Yu Z, Ngo D,
Benson MD
,
Chen ZZ
,
Cruz DE
, Shen D, Gao Y, Bouchard C, Sarzynski MA, Correa A,
Natarajan P
, Wilson JG,
Gerszten RE
. Proteomic profiling platforms head to head: Leveraging genetics and clinical traits to compare aptamer- and antibody-based methods. Sci Adv. 2022 08 19; 8(33):eabm5164.
PMID:
35984888
; PMCID:
PMC9390994
.
Citations:
6
Fields:
Sci
Science
Translation:
Humans
Kahn D, Macias E, Zarini S, Garfield A, Zemski Berry K,
Gerszten R
, Schoen J, Cree-Green M, Bergman BC. Quantifying the inflammatory secretome of human intermuscular adipose tissue. Physiol Rep. 2022 08; 10(16):e15424.
PMID:
35980018
; PMCID:
PMC9387112
.
Citations:
Fields:
Phy
Physiology
Translation:
Humans
Austin TR, McHugh CP, Brody JA, Bis JC, Sitlani CM, Bartz TM, Biggs ML, Bansal N, Buzkova P, Carr SA, deFilippi CR, Elkind MSV, Fink HA, Floyd JS, Fohner AE,
Gerszten RE
, Heckbert SR, Katz DH, Kizer JR, Lemaitre RN, Longstreth WT, McKnight B, Mei H,
Mukamal KJ
, Newman AB, Ngo D, Odden MC, Vasan RS, Shojaie A, Simon N, Smith GD, Davies NM, Siscovick DS, Sotoodehnia N, Tracy RP, Wiggins KL, Zheng J, Psaty BM. Proteomics and Population Biology in the Cardiovascular Health Study (CHS): design of a study with mentored access and active data sharing. Eur J Epidemiol. 2022 Jul; 37(7):755-765.
PMID:
35790642
; PMCID:
PMC9255954
.
Citations:
1
Fields:
Epi
Epidemiology
Translation:
Humans
Ooka T, Raita Y, Fujiogi M, Freishtat RJ,
Gerszten RE
,
Mansbach JM
,
Zhu Z
,
Camargo CA
,
Hasegawa K
. Proteomics endotyping of infants with severe bronchiolitis and risk of childhood asthma. Allergy. 2022 11; 77(11):3350-3361.
PMID:
35620861
; PMCID:
PMC9617778
.
Citations:
1
Fields:
All
Allergy and Immunology
Translation: