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John Ioannidis, Ph.D., M.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Wallach JD, Boyack KW, Ioannidis JPA. Reproducible research practices, transparency, and open access data in the biomedical literature, 2015-2017. PLoS Biol. 2018 Nov; 16(11):e2006930. PMID: 30457984.
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  2. Schuit E, Li AH, Ioannidis JPA. How often can meta-analyses of individual-level data individualize treatment? A meta-epidemiologic study. Int J Epidemiol. 2018 Nov 15. PMID: 30445577.
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  3. Ewald H, Speich B, Ladanie A, Bucher HC, Ioannidis JP, Hemkens LG. Marginal structural models and other analyses allow multiple estimates of treatment effects in randomized clinical trials: meta-epidemiological analysis. J Clin Epidemiol. 2018 Nov 10. PMID: 30423375.
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  4. Janiaud P, Cristea IA, Ioannidis JPA. Correction to: Industry-funded versus non-profit-funded critical care research: a meta-epidemiological overview. Intensive Care Med. 2018 Nov 08. PMID: 30406805.
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  5. Desai K, Carroll I, Asch S, Hernandez-Boussard T, Ioannidis JPA. Extremely large outlier treatment effects may be a footprint of bias in trials from less developed countries: randomized trials of gabapentinoids. J Clin Epidemiol. 2018 Oct 23. PMID: 30366063.
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  6. Guloksuz S, Rutten BPF, Pries LK, Ten Have M, de Graaf R, van Dorsselaer S, Klingenberg B, van Os J, Ioannidis JPA. The Complexities of Evaluating the Exposome in Psychiatry: A Data-Driven Illustration of Challenges and Some Propositions for Amendments. Schizophr Bull. 2018 Oct 17; 44(6):1175-1179. PMID: 30169883.
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  7. Manrai AK, Patel CJ, Ioannidis JPA. Using Big Data to Determine Reference Values for Laboratory Tests-Reply. JAMA. 2018 10 09; 320(14):1496. PMID: 30304422.
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  8. He Y, Li X, Gasevic D, Brunt E, McLachlan F, Millenson M, Timofeeva M, Ioannidis JPA, Campbell H, Theodoratou E. Statins and Multiple Noncardiovascular Outcomes: Umbrella Review of Meta-analyses of Observational Studies and Randomized Controlled Trials. Ann Intern Med. 2018 Oct 16; 169(8):543-553. PMID: 30304368.
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  9. Ioannidis JPA. Massive citations to misleading methods and research tools: Matthew effect, quotation error and citation copying. Eur J Epidemiol. 2018 Nov; 33(11):1021-1023. PMID: 30291530.
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  10. Cristea IA, Ioannidis JPA. Disclosures Can Always Be Improved-Reply. JAMA Psychiatry. 2018 Oct 03. PMID: 30285040.
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  11. Ioannidis JPA. Guidelines Do Not Entangle Practitioners With Unavoidable Conflicts as Authors, and When There Is No Evidence, Just Say So. Circ Cardiovasc Qual Outcomes. 2018 Oct; 11(10):e005205. PMID: 30354581.
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  12. Ioannidis JPA. Professional Societies Should Abstain From Authorship of Guidelines and Disease Definition Statements. Circ Cardiovasc Qual Outcomes. 2018 Oct; 11(10):e004889. PMID: 30354582.
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  13. Maggio LA, Thomas A, Chen HC, Ioannidis JPA, Kanter SL, Norton C, Tannery NH, Artino AR. Examining the readiness of best evidence in medical education guides for integration into educational practice: A meta-synthesis. Perspect Med Educ. 2018 Oct; 7(5):292-301. PMID: 30229529.
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  14. Djulbegovic B, Ioannidis JPA. Precision medicine for individual patients should use population group averages and larger, not smaller, groups. Eur J Clin Invest. 2018 Sep 25; e13031. PMID: 30251305.
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  15. Ishihara M, Harel D, Levis B, Levis AW, Riehm KE, Saadat N, Azar M, Rice DB, Sanchez TA, Chiovitti MJ, Cuijpers P, Gilbody S, Ioannidis JPA, Kloda LA, McMillan D, Patten SB, Shrier I, Arroll B, Bombardier CH, Butterworth P, Carter G, Clover K, Conwell Y, Goodyear-Smith F, Greeno CG, Hambridge J, Harrison PA, Hudson M, Jetté N, Kiely KM, McGuire A, Pence BW, Rooney AG, Sidebottom A, Simning A, Turner A, White J, Whooley MA, Winkley K, Benedetti A, Thombs BD. Shortening self-report mental health symptom measures through optimal test assembly methods: Development and validation of the Patient Health Questionnaire-Depression-4. Depress Anxiety. 2018 Sep 20. PMID: 30238571.
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  16. Cipriani A, Salanti G, Furukawa TA, Turner E, Ioannidis JPA, Geddes JR. Network meta-analysis of antidepressants - Authors' reply. Lancet. 2018 09 22; 392(10152):1012-1013. PMID: 30264703.
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  17. Ladanie A, Speich B, Naudet F, Agarwal A, Pereira TV, Sclafani F, Martin-Liberal J, Schmid T, Ewald H, Ioannidis JPA, Bucher HC, Kasenda B, Hemkens LG. The Comparative Effectiveness of Innovative Treatments for Cancer (CEIT-Cancer) project: Rationale and design of the database and the collection of evidence available at approval of novel drugs. Trials. 2018 Sep 19; 19(1):505. PMID: 30231912.
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  18. Ioannidis JPA. Rethink Funding. Sci Am. 2018 Sep 18; 319(4):52-55. PMID: 30273303.
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  19. Ioannidis JPA. The Challenge of Reforming Nutritional Epidemiologic Research. JAMA. 2018 Sep 11; 320(10):969-970. PMID: 30422271.
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  20. Ioannidis JPA. Lowering the P Value Threshold-Reply. JAMA. 2018 09 04; 320(9):937-938. PMID: 30193273.
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  21. Ioannidis JPA, Klavans R, Boyack KW. Thousands of scientists publish a paper every five days. Nature. 2018 Sep; 561(7722):167-169. PMID: 30209384.
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  22. Janiaud P, Dal-Ré R, Ioannidis JPA. Assessment of Pragmatism in Recently Published Randomized Clinical Trials. JAMA Intern Med. 2018 Sep 01; 178(9):1278-1280. PMID: 30039169.
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  23. Janiaud P, Cristea IA, Ioannidis JPA. Industry-funded versus non-profit-funded critical care research: a meta-epidemiological overview. Intensive Care Med. 2018 Oct; 44(10):1613-1627. PMID: 30151688.
    View in: PubMed
  24. Sotiriadis A, Makrydimas G, Papatheodorou S, Ioannidis JP, McGoldrick E. Corticosteroids for preventing neonatal respiratory morbidity after elective caesarean section at term. Cochrane Database Syst Rev. 2018 08 03; 8:CD006614. PMID: 30075059.
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  25. Hardwicke TE, Ioannidis JPA. Populating the Data Ark: An attempt to retrieve, preserve, and liberate data from the most highly-cited psychology and psychiatry articles. PLoS One. 2018; 13(8):e0201856. PMID: 30071110.
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  26. Shokraneh F, Adams CE, Clarke M, Amato L, Bastian H, Beller E, Brassey J, Buchbinder R, Davoli M, Del Mar C, Glasziou P, Gluud C, Heneghan C, Hoffmann T, Ioannidis JP, Jayaram M, Kwong J, Moher D, Ota E, Sheriff RS, Vale L, Goldacre B. Why Cochrane should prioritise sharing data. BMJ. 2018 Jul 30; 362:k3229. PMID: 30061322.
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  27. Machado MO, Veronese N, Sanches M, Stubbs B, Koyanagi A, Thompson T, Tzoulaki I, Solmi M, Vancampfort D, Schuch FB, Maes M, Fava GA, Ioannidis JPA, Carvalho AF. The association of depression and all-cause and cause-specific mortality: an umbrella review of systematic reviews and meta-analyses. BMC Med. 2018 07 20; 16(1):112. PMID: 30025524.
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  28. Solmi M, Correll CU, Carvalho AF, Ioannidis JPA. The role of meta-analyses and umbrella reviews in assessing the harms of psychotropic medications: beyond qualitative synthesis. Epidemiol Psychiatr Sci. 2018 Dec; 27(6):537-542. PMID: 30008278.
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  29. Ioannidis JPA, Trepanowski JF. Conflict of Interest in Nutrition Research-Reply. JAMA. 2018 07 03; 320(1):94-95. PMID: 29971394.
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  30. Trepanowski JF, Ioannidis JPA. Perspective: Limiting Dependence on Nonrandomized Studies and Improving Randomized Trials in Human Nutrition Research: Why and How. Adv Nutr. 2018 Jul 01; 9(4):367-377. PMID: 30032218.
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  31. Solmi M, Köhler CA, Stubbs B, Koyanagi A, Bortolato B, Monaco F, Vancampfort D, Machado MO, Maes M, Tzoulaki I, Firth J, Ioannidis JPA, Carvalho AF. Environmental risk factors and nonpharmacological and nonsurgical interventions for obesity: An umbrella review of meta-analyses of cohort studies and randomized controlled trials. Eur J Clin Invest. 2018 Jun 20; e12982. PMID: 29923186.
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  32. O'Sullivan JW, Muntinga T, Grigg S, Ioannidis JPA. Prevalence and outcomes of incidental imaging findings: umbrella review. BMJ. 2018 Jun 18; 361:k2387. PMID: 29914908.
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  33. Davies C, Cipriani A, Ioannidis JPA, Radua J, Stahl D, Provenzani U, McGuire P, Fusar-Poli P. Lack of evidence to favor specific preventive interventions in psychosis: a network meta-analysis. World Psychiatry. 2018 Jun; 17(2):196-209. PMID: 29856551.
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  34. Cristea IA, Ioannidis JPA. Improving Disclosure of Financial Conflicts of Interest for Research on Psychosocial Interventions. JAMA Psychiatry. 2018 Jun 01; 75(6):541-542. PMID: 29641818.
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  35. Köhler CA, Evangelou E, Stubbs B, Solmi M, Veronese N, Belbasis L, Bortolato B, Melo MCA, Coelho CA, Fernandes BS, Olfson M, Ioannidis JPA, Carvalho AF. Mapping risk factors for depression across the lifespan: An umbrella review of evidence from meta-analyses and Mendelian randomization studies. J Psychiatr Res. 2018 Aug; 103:189-207. PMID: 29886003.
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  36. Ladanie A, Ioannidis JPA, Stafford RS, Ewald H, Bucher HC, Hemkens LG, Hemkens LG. Off-label prescription: experience is a gloomy lantern that does not even illuminate its bearer. Author response. J Clin Epidemiol. 2018 Sep; 101:127-128. PMID: 29800688.
    View in: PubMed
  37. Cristea IA, Ioannidis JPA. P values in display items are ubiquitous and almost invariably significant: A survey of top science journals. PLoS One. 2018; 13(5):e0197440. PMID: 29763472.
    View in: PubMed
  38. Manrai AK, Patel CJ, Ioannidis JPA. In the Era of Precision Medicine and Big Data, Who Is Normal? JAMA. 2018 May 15; 319(19):1981-1982. PMID: 29710130.
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  39. Ioannidis JPA. All science should inform policy and regulation. PLoS Med. 2018 May; 15(5):e1002576. PMID: 29723196.
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  40. Levis B, Benedetti A, Riehm KE, Saadat N, Levis AW, Azar M, Rice DB, Chiovitti MJ, Sanchez TA, Cuijpers P, Gilbody S, Ioannidis JPA, Kloda LA, McMillan D, Patten SB, Shrier I, Steele RJ, Ziegelstein RC, Akena DH, Arroll B, Ayalon L, Baradaran HR, Baron M, Beraldi A, Bombardier CH, Butterworth P, Carter G, Chagas MH, Chan JCN, Cholera R, Chowdhary N, Clover K, Conwell Y, de Man-van Ginkel JM, Delgadillo J, Fann JR, Fischer FH, Fischler B, Fung D, Gelaye B, Goodyear-Smith F, Greeno CG, Hall BJ, Hambridge J, Harrison PA, Hegerl U, Hides L, Hobfoll SE, Hudson M, Hyphantis T, Inagaki M, Ismail K, Jetté N, Khamseh ME, Kiely KM, Lamers F, Liu SI, Lotrakul M, Loureiro SR, Löwe B, Marsh L, McGuire A, Mohd Sidik S, Munhoz TN, Muramatsu K, Osório FL, Patel V, Pence BW, Persoons P, Picardi A, Rooney AG, Santos IS, Shaaban J, Sidebottom A, Simning A, Stafford L, Sung S, Tan PLL, Turner A, van der Feltz-Cornelis CM, van Weert HC, Vöhringer PA, White J, Whooley MA, Winkley K, Yamada M, Zhang Y, Thombs BD. Probability of major depression diagnostic classification using semi-structured versus fully structured diagnostic interviews. Br J Psychiatry. 2018 Jun; 212(6):377-385. PMID: 29717691.
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  41. Ioannidis JPA, Khoury MJ. Evidence-based medicine and big genomic data. Hum Mol Genet. 2018 May 01; 27(R1):R2-R7. PMID: 29474574.
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  42. Azad TD, Veeravagu A, Mittal V, Esparza R, Johnson E, Ioannidis JPA, Grant GA. Neurosurgical Randomized Controlled Trials-Distance Travelled. Neurosurgery. 2018 May 01; 82(5):604-612. PMID: 28645203.
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  43. Patel CJ, Bhattacharya J, Ioannidis JPA, Bendavid E. Systematic identification of correlates of HIV infection: an X-wide association study. AIDS. 2018 Apr 24; 32(7):933-943. PMID: 29424772.
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  44. Ioannidis JPA. Randomized controlled trials: Often flawed, mostly useless, clearly indispensable: A commentary on Deaton and Cartwright. Soc Sci Med. 2018 Aug; 210:53-56. PMID: 29776687.
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  45. David SP, Naudet F, Laude J, Radua J, Fusar-Poli P, Chu I, Stefanick ML, Ioannidis JPA. Potential Reporting Bias in Neuroimaging Studies of Sex Differences. Sci Rep. 2018 Apr 17; 8(1):6082. PMID: 29666377.
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  46. Møller MH, Ioannidis JPA, Darmon M. Are systematic reviews and meta-analyses still useful research? We are not sure. Intensive Care Med. 2018 04; 44(4):518-520. PMID: 29663048.
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  47. Ioannidis JPA. The Proposal to Lower P Value Thresholds to .005. JAMA. 2018 04 10; 319(14):1429-1430. PMID: 29566133.
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  48. Cipriani A, Salanti G, Furukawa TA, Egger M, Leucht S, Ruhe HG, Turner EH, Atkinson LZ, Chaimani A, Higgins JPT, Ogawa Y, Takeshima N, Hayasaka Y, Imai H, Shinohara K, Tajika A, Ioannidis JPA, Geddes JR. Antidepressants might work for people with major depression: where do we go from here? Lancet Psychiatry. 2018 Jun; 5(6):461-463. PMID: 29628364.
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  49. Dal-Ré R, Janiaud P, Ioannidis JPA. Real-world evidence: How pragmatic are randomized controlled trials labeled as pragmatic? BMC Med. 2018 04 03; 16(1):49. PMID: 29615035.
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  50. Flegal KM, Ioannidis JPA. The Obesity Paradox: A Misleading Term That Should Be Abandoned. Obesity (Silver Spring). 2018 04; 26(4):629-630. PMID: 29570246.
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  51. Moher D, Naudet F, Cristea IA, Miedema F, Ioannidis JPA, Goodman SN. Assessing scientists for hiring, promotion, and tenure. PLoS Biol. 2018 Mar; 16(3):e2004089. PMID: 29596415.
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  52. Ioannidis JPA. Meta-analyses in environmental and occupational health. Occup Environ Med. 2018 Jun; 75(6):443-445. PMID: 29574405.
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  53. Ioannidis JPA. Meta-research: Why research on research matters. PLoS Biol. 2018 Mar; 16(3):e2005468. PMID: 29534060.
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  54. Kim SK, Ioannidis JPA, Ahmed MA, Avins AL, Kleimeyer JP, Fredericson M, Dragoo JL. Two Genetic Variants Associated with Plantar Fascial Disorders. Int J Sports Med. 2018 Apr; 39(4):314-321. PMID: 29534260.
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  55. Stergiou GS, Alpert B, Mieke S, Asmar R, Atkins N, Eckert S, Frick G, Friedman B, Graßl T, Ichikawa T, Ioannidis JP, Lacy P, McManus R, Murray A, Myers M, Palatini P, Parati G, Quinn D, Sarkis J, Shennan A, Usuda T, Wang J, Wu CO, O'Brien E. A universal standard for the validation of blood pressure measuring devices: Association for the Advancement of Medical Instrumentation/European Society of Hypertension/International Organization for Standardization (AAMI/ESH/ISO) Collaboration Statement. J Hypertens. 2018 Mar; 36(3):472-478. PMID: 29384983.
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  56. Fanelli D, Ioannidis JPA, Goodman S. Improving the integrity of published science: An expanded taxonomy of retractions and corrections. Eur J Clin Invest. 2018 Apr; 48(4). PMID: 29369337.
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  57. Cipriani A, Furukawa TA, Salanti G, Chaimani A, Atkinson LZ, Ogawa Y, Leucht S, Ruhe HG, Turner EH, Higgins JPT, Egger M, Takeshima N, Hayasaka Y, Imai H, Shinohara K, Tajika A, Ioannidis JPA, Geddes JR. Comparative efficacy and acceptability of 21 antidepressant drugs for the acute treatment of adults with major depressive disorder: a systematic review and network meta-analysis. Lancet. 2018 04 07; 391(10128):1357-1366. PMID: 29477251.
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  58. Gardner CD, Trepanowski JF, Del Gobbo LC, Hauser ME, Rigdon J, Ioannidis JPA, Desai M, King AC. Effect of Low-Fat vs Low-Carbohydrate Diet on 12-Month Weight Loss in Overweight Adults and the Association With Genotype Pattern or Insulin Secretion: The DIETFITS Randomized Clinical Trial. JAMA. 2018 02 20; 319(7):667-679. PMID: 29466592.
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  59. Ioannidis JPA, Trepanowski JF. Disclosures in Nutrition Research: Why It Is Different. JAMA. 2018 02 13; 319(6):547-548. PMID: 29222543.
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  60. Naudet F, Sakarovitch C, Janiaud P, Cristea I, Fanelli D, Moher D, Ioannidis JPA. Data sharing and reanalysis of randomized controlled trials in leading biomedical journals with a full data sharing policy: survey of studies published in The BMJ and PLOS Medicine. BMJ. 2018 02 13; 360:k400. PMID: 29440066.
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  61. Djulbegovic B, Glasziou P, Klocksieben FA, Reljic T, VanDenBergh M, Mhaskar R, Ioannidis JPA, Chalmers I. Larger effect sizes in nonrandomized studies are associated with higher rates of EMA licensing approval. J Clin Epidemiol. 2018 Jun; 98:24-32. PMID: 29432860.
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  62. Radua J, Ramella-Cravaro V, Ioannidis JPA, Reichenberg A, Phiphopthatsanee N, Amir T, Yenn Thoo H, Oliver D, Davies C, Morgan C, McGuire P, Murray RM, Fusar-Poli P. What causes psychosis? An umbrella review of risk and protective factors. World Psychiatry. 2018 Feb; 17(1):49-66. PMID: 29352556.
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  63. Stergiou GS, Alpert B, Mieke S, Asmar R, Atkins N, Eckert S, Frick G, Friedman B, Graßl T, Ichikawa T, Ioannidis JP, Lacy P, McManus R, Murray A, Myers M, Palatini P, Parati G, Quinn D, Sarkis J, Shennan A, Usuda T, Wang J, Wu CO, O'Brien E. A Universal Standard for the Validation of Blood Pressure Measuring Devices: Association for the Advancement of Medical Instrumentation/European Society of Hypertension/International Organization for Standardization (AAMI/ESH/ISO) Collaboration Statement. Hypertension. 2018 Mar; 71(3):368-374. PMID: 29386350.
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  64. Rattray NJW, Deziel NC, Wallach JD, Khan SA, Vasiliou V, Ioannidis JPA, Johnson CH. Beyond genomics: understanding exposotypes through metabolomics. Hum Genomics. 2018 01 26; 12(1):4. PMID: 29373992.
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  65. Serghiou S, Ioannidis JPA. Altmetric Scores, Citations, and Publication of Studies Posted as Preprints. JAMA. 2018 01 23; 319(4):402-404. PMID: 29362788.
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  66. Flacco ME, Manzoli L, Rosso A, Marzuillo C, Bergamini M, Stefanati A, Cultrera R, Villari P, Ricciardi W, Ioannidis JPA, Contopoulos-Ioannidis DG. Immunogenicity and safety of the multicomponent meningococcal B vaccine (4CMenB) in children and adolescents: a systematic review and meta-analysis. Lancet Infect Dis. 2018 Apr; 18(4):461-472. PMID: 29371070.
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  67. Mc Cord KA, Al-Shahi Salman R, Treweek S, Gardner H, Strech D, Whiteley W, Ioannidis JPA, Hemkens LG. Routinely collected data for randomized trials: promises, barriers, and implications. Trials. 2018 Jan 11; 19(1):29. PMID: 29325575.
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  68. Parish AJ, Boyack KW, Ioannidis JPA. Dynamics of co-authorship and productivity across different fields of scientific research. PLoS One. 2018; 13(1):e0189742. PMID: 29320509.
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  69. Grimes DR, Bauch CT, Ioannidis JPA. Modelling science trustworthiness under publish or perish pressure. R Soc Open Sci. 2018 Jan; 5(1):171511. PMID: 29410855.
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  70. Ioannidis JPA. Diagnosis and Treatment of Hypertension in the 2017 ACC/AHA Guidelines and in the Real World. JAMA. 2018 Jan 09; 319(2):115-116. PMID: 29242891.
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  71. Moubayed SP, Ioannidis JPA, Saltychev M, Most SP. The 10-Item Standardized Cosmesis and Health Nasal Outcomes Survey (SCHNOS) for Functional and Cosmetic Rhinoplasty. JAMA Facial Plast Surg. 2018 Jan 01; 20(1):37-42. PMID: 28880988.
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  72. Roos TR, Roos AK, Avins AL, Ahmed MA, Kleimeyer JP, Fredericson M, Ioannidis JPA, Dragoo JL, Kim SK. Genome-wide association study identifies a locus associated with rotator cuff injury. PLoS One. 2017; 12(12):e0189317. PMID: 29228018.
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  73. Shenkin SD, Harrison JK, Wilkinson T, Dodds RM, Ioannidis JPA. Corrigendum: Systematic reviews: guidance relevant for studies of older people. Age Ageing. 2017 Dec 02; 1. PMID: 29211824.
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  74. Naudet F, Schuit E, Ioannidis JPA. Overlapping network meta-analyses on the same topic: survey of published studies. Int J Epidemiol. 2017 12 01; 46(6):1999-2008. PMID: 29040566.
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  75. Tedesco D, Farid-Kapadia M, Offringa M, Bhutta ZA, Maldonado Y, Ioannidis JPA, Contopoulos-Ioannidis DG. Comparative evidence on harms in pediatric randomized clinical trials from less developed versus more developed countries is limited. J Clin Epidemiol. 2018 Mar; 95:63-72. PMID: 29191447.
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  76. Steyerberg EW, Uno H, Ioannidis JPA, van Calster B. Poor performance of clinical prediction models: the harm of commonly applied methods. J Clin Epidemiol. 2018 Jun; 98:133-143. PMID: 29174118.
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  77. Rezende LFM, Sá TH, Markozannes G, Rey-López JP, Lee IM, Tsilidis KK, Ioannidis JPA, Eluf-Neto J. Physical activity and cancer: an umbrella review of the literature including 22 major anatomical sites and 770?000 cancer cases. Br J Sports Med. 2018 Jul; 52(13):826-833. PMID: 29146752.
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  78. Ladanie A, Ioannidis JPA, Stafford RS, Ewald H, Bucher HC, Hemkens LG. Off-label treatments were not consistently better or worse than approved drug treatments in randomized trials. J Clin Epidemiol. 2018 Feb; 94:35-45. PMID: 29146289.
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  79. Ioannidis JPA. Greece: Crisis, smoking and tobacco conflicts in social media. Eur J Clin Invest. 2017 12; 47(12). PMID: 28981138.
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  80. Goldfeder RL, Wall DP, Khoury MJ, Ioannidis JPA, Ashley EA. Human Genome Sequencing at the Population Scale: A Primer on High-Throughput DNA Sequencing and Analysis. Am J Epidemiol. 2017 Oct 15; 186(8):1000-1009. PMID: 29040395.
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  81. Kim SK, Ahmed MA, Avins AL, Ioannidis JPA. A Genetic Marker Associated with De Quervain's Tenosynovitis. Int J Sports Med. 2017 Nov; 38(12):942-948. PMID: 28985641.
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  82. Kim SK, Kleimeyer JP, Ahmed MA, Avins AL, Fredericson M, Dragoo JL, Ioannidis JPA. Two genetic loci associated with ankle injury. PLoS One. 2017; 12(9):e0185355. PMID: 28957384.
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  83. Ioannidis JPA, Stuart ME, Brownlee S, Strite SA. How to survive the medical misinformation mess. Eur J Clin Invest. 2017 Nov; 47(11):795-802. PMID: 28881000.
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  84. Hemkens LG, Ewald H, Naudet F, Ladanie A, Shaw JG, Sajeev G, Ioannidis JPA. Interpretation of epidemiologic studies very often lacked adequate consideration of confounding. J Clin Epidemiol. 2018 Jan; 93:94-102. PMID: 28943377.
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  85. Shenkin SD, Harrison JK, Wilkinson T, Dodds RM, Ioannidis JPA. Systematic reviews: guidance relevant for studies of older people. Age Ageing. 2017 09 01; 46(5):722-728. PMID: 28655142.
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  86. Theodoratou E, Timofeeva M, Li X, Meng X, Ioannidis JPA. Nature, Nurture, and Cancer Risks: Genetic and Nutritional Contributions to Cancer. Annu Rev Nutr. 2017 08 21; 37:293-320. PMID: 28826375.
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  87. Knowles JW, Zarafshar S, Pavlovic A, Goldstein BA, Tsai S, Li J, McConnell MV, Absher D, Ashley EA, Kiernan M, Ioannidis JPA, Assimes TL. Impact of a Genetic Risk Score for Coronary Artery Disease on Reducing Cardiovascular Risk: A Pilot Randomized Controlled Study. Front Cardiovasc Med. 2017; 4:53. PMID: 28856136.
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  88. Szucs D, Ioannidis JPA. When Null Hypothesis Significance Testing Is Unsuitable for Research: A Reassessment. Front Hum Neurosci. 2017; 11:390. PMID: 28824397.
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  89. Ioannidis JPA. Inconsistent Guideline Recommendations for Cardiovascular Prevention and the Debate About Zeroing in on and Zeroing LDL-C Levels With PCSK9 Inhibitors. JAMA. 2017 Aug 01; 318(5):419-420. PMID: 28738115.
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  90. Hoffmann TC, Oxman AD, Ioannidis JP, Moher D, Lasserson TJ, Tovey DI, Stein K, Sutcliffe K, Ravaud P, Altman DG, Perera R, Glasziou P. Enhancing the usability of systematic reviews by improving the consideration and description of interventions. BMJ. 2017 07 20; 358:j2998. PMID: 28729459.
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  91. Magni P, Bier DM, Pecorelli S, Agostoni C, Astrup A, Brighenti F, Cook R, Folco E, Fontana L, Gibson RA, Guerra R, Guyatt GH, Ioannidis JP, Jackson AS, Klurfeld DM, Makrides M, Mathioudakis B, Monaco A, Patel CJ, Racagni G, Schünemann HJ, Shamir R, Zmora N, Peracino A. Perspective: Improving Nutritional Guidelines for Sustainable Health Policies: Current Status and Perspectives. Adv Nutr. 2017 Jul; 8(4):532-545. PMID: 28710141.
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  92. Simoneau G, Levis B, Cuijpers P, Ioannidis JPA, Patten SB, Shrier I, Bombardier CH, de Lima Osório F, Fann JR, Gjerdingen D, Lamers F, Lotrakul M, Löwe B, Shaaban J, Stafford L, van Weert HCPM, Whooley MA, Wittkampf KA, Yeung AS, Thombs BD, Benedetti A. A comparison of bivariate, multivariate random-effects, and Poisson correlated gamma-frailty models to meta-analyze individual patient data of ordinal scale diagnostic tests. Biom J. 2017 Nov; 59(6):1317-1338. PMID: 28692782.
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  93. Ioannidis JPA. Defending Biomedical Science in an Era of Threatened Funding. JAMA. 2017 Jun 27; 317(24):2483-2484. PMID: 28459974.
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  94. Ioannidis JPA. Nonreproducibility of Preclinical Research-Reply. JAMA. 2017 06 20; 317(23):2453. PMID: 28632861.
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  95. Li X, Meng X, Timofeeva M, Tzoulaki I, Tsilidis KK, Ioannidis JP, Campbell H, Theodoratou E. Serum uric acid levels and multiple health outcomes: umbrella review of evidence from observational studies, randomised controlled trials, and Mendelian randomisation studies. BMJ. 2017 06 07; 357:j2376. PMID: 28592419.
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  96. Naci H, Wouters OJ, Gupta R, Ioannidis JPA. Timing and Characteristics of Cumulative Evidence Available on Novel Therapeutic Agents Receiving Food and Drug Administration Accelerated Approval. Milbank Q. 2017 06; 95(2):261-290. PMID: 28589600.
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  97. Kim S, Kleimeyer JP, Ahmed MA, Avins AL, Fredericson M, Dragoo JL, Ioannidis JPA. Int J Sports Med. 2017 Jul; 38(7):508-514. PMID: 28521375.
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  98. Levis B, Benedetti A, Levis AW, Ioannidis JPA, Shrier I, Cuijpers P, Gilbody S, Kloda LA, McMillan D, Patten SB, Steele RJ, Ziegelstein RC, Bombardier CH, de Lima Osório F, Fann JR, Gjerdingen D, Lamers F, Lotrakul M, Loureiro SR, Löwe B, Shaaban J, Stafford L, van Weert HCPM, Whooley MA, Williams LS, Wittkampf KA, Yeung AS, Thombs BD. Selective Cutoff Reporting in Studies of Diagnostic Test Accuracy: A Comparison of Conventional and Individual-Patient-Data Meta-Analyses of the Patient Health Questionnaire-9 Depression Screening Tool. Am J Epidemiol. 2017 05 15; 185(10):954-964. PMID: 28419203.
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  99. Roos AK, Avins AL, Ahmed MA, Kleimeyer JP, Roos TR, Fredericson M, Ioannidis JPA, Dragoo JL, Kim S. Two Genetic Loci associated with Medial Collateral Ligament Injury. Int J Sports Med. 2017 Jul; 38(7):501-507. PMID: 28482362.
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  100. Gall T, Ioannidis JPA, Maniadis Z. The credibility crisis in research: Can economics tools help? PLoS Biol. 2017 04; 15(4):e2001846. PMID: 28445470.
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  101. Flegal KM, Ioannidis JPA. A meta-analysis but not a systematic review: an evaluation of the Global BMI Mortality Collaboration. J Clin Epidemiol. 2017 08; 88:21-29. PMID: 28435099.
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  102. Flegal KM, Ioannidis JPA. A meta-analysis of individual participant data constructed to align with prior expert views: comments on Bhupathiraju et al. J Clin Epidemiol. 2017 08; 88:33-36. PMID: 28411080.
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  103. Ioannidis JPA. Hijacked evidence-based medicine: stay the course and throw the pirates overboard. J Clin Epidemiol. 2017 Apr; 84:11-13. PMID: 28532611.
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  104. Wallach JD, Sullivan PG, Trepanowski JF, Sainani KL, Steyerberg EW, Ioannidis JP. Evaluation of Evidence of Statistical Support and Corroboration of Subgroup Claims in Randomized Clinical Trials. JAMA Intern Med. 2017 04 01; 177(4):554-560. PMID: 28192563.
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  105. Ioannidis JP. Meta-analyses Can Be Credible and Useful: A New Standard. JAMA Psychiatry. 2017 04 01; 74(4):311-312. PMID: 28241194.
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  106. Kim SK, Roos TR, Roos AK, Kleimeyer JP, Ahmed MA, Goodlin GT, Fredericson M, Ioannidis JP, Avins AL, Dragoo JL. Genome-wide association screens for Achilles tendon and ACL tears and tendinopathy. PLoS One. 2017; 12(3):e0170422. PMID: 28358823.
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  107. Lipworth W, Mason PH, Kerridge I, Ioannidis JPA. Ethics and Epistemology in Big Data Research. J Bioeth Inq. 2017 Dec; 14(4):489-500. PMID: 28321561.
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  108. Fanelli D, Costas R, Ioannidis JP. Meta-assessment of bias in science. Proc Natl Acad Sci U S A. 2017 04 04; 114(14):3714-3719. PMID: 28320937.
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  109. Bourgeois FT, Orenstein L, Ballakur S, Mandl KD, Ioannidis JPA. Exclusion of Elderly People from Randomized Clinical Trials of Drugs for Ischemic Heart Disease. J Am Geriatr Soc. 2017 Nov; 65(11):2354-2361. PMID: 28306144.
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  110. Ioannidis JPA. The Reproducibility Wars: Successful, Unsuccessful, Uninterpretable, Exact, Conceptual, Triangulated, Contested Replication. Clin Chem. 2017 05; 63(5):943-945. PMID: 28298413.
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  111. Ioannidis JP. Acknowledging and Overcoming Nonreproducibility in Basic and Preclinical Research. JAMA. 2017 Mar 14; 317(10):1019-1020. PMID: 28192565.
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  112. Neumann K, Grittner U, Piper SK, Rex A, Florez-Vargas O, Karystianis G, Schneider A, Wellwood I, Siegerink B, Ioannidis JP, Kimmelman J, Dirnagl U. Increasing efficiency of preclinical research by group sequential designs. PLoS Biol. 2017 03; 15(3):e2001307. PMID: 28282371.
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  113. van Ravenzwaaij D, Ioannidis JP. A simulation study of the strength of evidence in the recommendation of medications based on two trials with statistically significant results. PLoS One. 2017; 12(3):e0173184. PMID: 28273140.
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  114. Ioannidis JPA, Bossuyt PMM. Waste, Leaks, and Failures in the Biomarker Pipeline. Clin Chem. 2017 05; 63(5):963-972. PMID: 28270433.
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  115. Szucs D, Ioannidis JP. Empirical assessment of published effect sizes and power in the recent cognitive neuroscience and psychology literature. PLoS Biol. 2017 03; 15(3):e2000797. PMID: 28253258.
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  116. Holubar M, Stavroulakis MC, Maldonado Y, Ioannidis JP, Contopoulos-Ioannidis D. Impact of vaccine herd-protection effects in cost-effectiveness analyses of childhood vaccinations. A quantitative comparative analysis. PLoS One. 2017; 12(3):e0172414. PMID: 28249046.
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  117. Ioannidis J. Next-generation systematic reviews: prospective meta-analysis, individual-level data, networks and umbrella reviews. Br J Sports Med. 2017 Oct; 51(20):1456-1458. PMID: 28223307.
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  118. Ioannidis JP, Caplan AL, Dal-Ré R. Outcome reporting bias in clinical trials: why monitoring matters. BMJ. 2017 Feb 14; 356:j408. PMID: 28196819.
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  119. Ioannidis JP. Does evidence-based hearsay determine the use of medical treatments? Soc Sci Med. 2017 03; 177:256-258. PMID: 28190627.
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  120. Stanley TD, Doucouliagos H, Ioannidis JP. Finding the power to reduce publication bias. Stat Med. 2017 05 10; 36(10):1580-1598. PMID: 28127782.
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  121. Joyner MJ, Paneth N, Ioannidis JP. Underperforming Big Ideas in Biomedical Research-Reply. JAMA. 2017 01 17; 317(3):322. PMID: 28114549.
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  122. Saini V, Garcia-Armesto S, Klemperer D, Paris V, Elshaug AG, Brownlee S, Ioannidis JPA, Fisher ES. Drivers of poor medical care. Lancet. 2017 07 08; 390(10090):178-190. PMID: 28077235.
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  123. Karczewski KJ, Tatonetti NP, Manrai AK, Patel CJ, Titus Brown C, Ioannidis JPA. METHODS TO ENSURE THE REPRODUCIBILITY OF BIOMEDICAL RESEARCH. Pac Symp Biocomput. 2017; 22:117-119. PMID: 27896967.
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  124. Stanton MV, Robinson JL, Kirkpatrick SM, Farzinkhou S, Avery EC, Rigdon J, Offringa LC, Trepanowski JF, Hauser ME, Hartle JC, Cherin RJ, King AC, Ioannidis JP, Desai M, Gardner CD. DIETFITS study (diet intervention examining the factors interacting with treatment success) - Study design and methods. Contemp Clin Trials. 2017 02; 53:151-161. PMID: 28027950.
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  125. Annesley T, Scott M, Bastian H, Fonseca V, Ioannidis JP, Keller MA, Polka J. Biomedical Journals and Preprint Services: Friends or Foes? Clin Chem. 2017 Feb; 63(2):453-458. PMID: 27998906.
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  126. Hemkens LG, Contopoulos-Ioannidis DG, Ioannidis JP. Authors' reply to Pérol and colleagues. BMJ. 2016 12 16; 355:i6747. PMID: 27986652.
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  127. Stavropoulou C, Parmar D, Ioannidis JP. Research authors' reply to Barlow and Barr and Taylor-Robinson. BMJ. 2016 12 16; 355:i6639. PMID: 27986758.
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  128. Stodden V, McNutt M, Bailey DH, Deelman E, Gil Y, Hanson B, Heroux MA, Ioannidis JP, Taufer M. Enhancing reproducibility for computational methods. Science. 2016 12 09; 354(6317):1240-1241. PMID: 27940837.
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  129. Schuit E, Ioannidis JP. Network meta-analyses performed by contracting companies and commissioned by industry. Syst Rev. 2016 11 25; 5(1):198. PMID: 27884175.
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  130. Wallach JD, Sullivan PG, Trepanowski JF, Steyerberg EW, Ioannidis JP. Sex based subgroup differences in randomized controlled trials: empirical evidence from Cochrane meta-analyses. BMJ. 2016 Nov 24; 355:i5826. PMID: 27884869.
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  131. Doufas AG, Panagiotou OA, Panousis P, Wong SS, Ioannidis JP. Insomnia From Drug Treatments: Evidence From Meta-analyses of Randomized Trials and Concordance With Prescribing Information. Mayo Clin Proc. 2017 Jan; 92(1):72-87. PMID: 27842706.
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  132. Laliotis I, Ioannidis JPA, Stavropoulou C. Total and cause-specific mortality before and after the onset of the Greek economic crisis: an interrupted time-series analysis. Lancet Public Health. 2016 12; 1(2):e56-e65. PMID: 29253418.
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  133. Markozannes G, Tzoulaki I, Karli D, Evangelou E, Ntzani E, Gunter MJ, Norat T, Ioannidis JP, Tsilidis KK. Diet, body size, physical activity and risk of prostate cancer: An umbrella review of the evidence. Eur J Cancer. 2016 12; 69:61-69. PMID: 27816833.
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  134. Nagendran M, Pereira TV, Kiew G, Altman DG, Maruthappu M, Ioannidis JP, McCulloch P. Very large treatment effects in randomised trials as an empirical marker to indicate whether subsequent trials are necessary: meta-epidemiological assessment. BMJ. 2016 Oct 27; 355:i5432. PMID: 27789483.
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  135. Joyner MJ, Paneth N, Ioannidis JP. What Happens When Underperforming Big Ideas in Research Become Entrenched? JAMA. 2016 Oct 04; 316(13):1355-1356. PMID: 27467098.
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  136. Macciocchi D, Lanini S, Vairo F, Zumla A, Figueiredo LT, Lauria FN, Strada G, Brouqui P, Puro V, Krishna S, Kremsner P, Scognamiglio P, Köhler C, Nicastri E, Di Caro A, Cieri RM, Ioannidis JP, Kobinger G, Burattini MN, Ippolito G. Short-term economic impact of the Zika virus outbreak. New Microbiol. 2016 Oct; 39(4):287-289. PMID: 28004846.
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  137. Sweeney TE, Haynes WA, Vallania F, Ioannidis JP, Khatri P. Methods to increase reproducibility in differential gene expression via meta-analysis. Nucleic Acids Res. 2017 01 09; 45(1):e1. PMID: 27634930.
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  138. Parmar D, Stavropoulou C, Ioannidis JP. Health outcomes during the 2008 financial crisis in Europe: systematic literature review. BMJ. 2016 Sep 06; 354:i4588. PMID: 27601477; PMCID: PMC5013230.
  139. Ioannidis JP, Boyack K, Wouters PF. Citation Metrics: A Primer on How (Not) to Normalize. PLoS Biol. 2016 09; 14(9):e1002542. PMID: 27599158.
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  140. Bellou V, Belbasis L, Tzoulaki I, Middleton LT, Ioannidis JPA, Evangelou E. Systematic evaluation of the associations between environmental risk factors and dementia: An umbrella review of systematic reviews and meta-analyses. Alzheimers Dement. 2017 Apr; 13(4):406-418. PMID: 27599208.
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  141. Ioannidis JP. The Mass Production of Redundant, Misleading, and Conflicted Systematic Reviews and Meta-analyses. Milbank Q. 2016 09; 94(3):485-514. PMID: 27620683.
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  142. Ioannidis JP. Making Optimal Use of and Extending beyond Polygenic Additive Liability Models. Hum Hered. 2015; 80(4):158-61. PMID: 27576754.
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  143. Sullivan PG, Wallach JD, Ioannidis JP. Meta-Analysis Comparing Established Risk Prediction Models (EuroSCORE II, STS Score, and ACEF Score) for Perioperative Mortality During Cardiac Surgery. Am J Cardiol. 2016 Nov 15; 118(10):1574-1582. PMID: 27687052.
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  144. Ioannidis JP, Klavans R, Boyack KW. Correction: Multiple Citation Indicators and Their Composite across Scientific Disciplines. PLoS Biol. 2016 Aug; 14(8):e1002548. PMID: 27548059.
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  145. Donadeu FX, Mohammed BT, Ioannidis J. A miRNA target network putatively involved in follicular atresia. Domest Anim Endocrinol. 2017 01; 58:76-83. PMID: 27664382.
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  146. Debray TP, Schuit E, Efthimiou O, Reitsma JB, Ioannidis JP, Salanti G, Moons KG. An overview of methods for network meta-analysis using individual participant data: when do benefits arise? Stat Methods Med Res. 2018 May; 27(5):1351-1364. PMID: 27487843.
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  147. Patel CJ, Ji J, Sundquist J, Ioannidis JP, Sundquist K. Systematic assessment of pharmaceutical prescriptions in association with cancer risk: a method to conduct a population-wide medication-wide longitudinal study. Sci Rep. 2016 08 10; 6:31308. PMID: 27507038.
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  148. Ioannidis JP. Stealth Research and Theranos: Reflections and Update 1 Year Later. JAMA. 2016 Jul 26; 316(4):389-90. PMID: 27191700.
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  149. Kennedy AE, Khoury MJ, Ioannidis JP, Brotzman M, Miller A, Lane C, Lai GY, Rogers SD, Harvey C, Elena JW, Seminara D. The Cancer Epidemiology Descriptive Cohort Database: A Tool to Support Population-Based Interdisciplinary Research. Cancer Epidemiol Biomarkers Prev. 2016 10; 25(10):1392-1401. PMID: 27439404.
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  150. IntHout J, Ioannidis JP, Rovers MM, Goeman JJ. Plea for routinely presenting prediction intervals in meta-analysis. BMJ Open. 2016 07 12; 6(7):e010247. PMID: 27406637; PMCID: PMC4947751.
  151. Flacco ME, Manzoli L, Boccia S, Puggina A, Rosso A, Marzuillo C, Scaioli G, Gualano MR, Ricciardi W, Villari P, Ioannidis JP. Registered Randomized Trials Comparing Generic and Brand-Name Drugs: A Survey. Mayo Clin Proc. 2016 Aug; 91(8):1021-34. PMID: 27402583.
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  152. Ebrahim S, Montoya L, Kamal El Din M, Sohani ZN, Agarwal A, Bance S, Saquib J, Saquib N, Ioannidis JP. Randomized trials are frequently fragmented in multiple secondary publications. J Clin Epidemiol. 2016 11; 79:130-139. PMID: 27387965.
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  153. Ioannidis JP, Klavans R, Boyack KW. Multiple Citation Indicators and Their Composite across Scientific Disciplines. PLoS Biol. 2016 07; 14(7):e1002501. PMID: 27367269.
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  154. Verghese A, Charlton B, Kassirer JP, Ramsey M, Ioannidis JP. The Reply. Am J Med. 2016 07; 129(7):e85. PMID: 27320713.
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  155. Serghiou S, Kyriakopoulou A, Ioannidis JP. Long noncoding RNAs as novel predictors of survival in human cancer: a systematic review and meta-analysis. Mol Cancer. 2016 06 28; 15(1):50. PMID: 27352941; PMCID: PMC4924330.
  156. Ioannidis JP. Why Most Clinical Research Is Not Useful. PLoS Med. 2016 06; 13(6):e1002049. PMID: 27328301.
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  157. Kaw R, Hernandez AV, Pasupuleti V, Deshpande A, Nagarajan V, Bueno H, Coleman CI, Ioannidis JP, Bhatt DL, Blackstone EH. Effect of diastolic dysfunction on postoperative outcomes after cardiovascular surgery: A systematic review and meta-analysis. J Thorac Cardiovasc Surg. 2016 10; 152(4):1142-53. PMID: 27364601.
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  158. Goodman SN, Fanelli D, Ioannidis JP. What does research reproducibility mean? Sci Transl Med. 2016 06 01; 8(341):341ps12. PMID: 27252173.
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  159. Clutter DS, Fessel WJ, Rhee SY, Hurley LB, Klein DB, Ioannidis JP, Silverberg MJ, Shafer RW. Response to Therapy in Antiretroviral Therapy-Naive Patients With Isolated Nonnucleoside Reverse Transcriptase Inhibitor-Associated Transmitted Drug Resistance. J Acquir Immune Defic Syndr. 2016 06 01; 72(2):171-6. PMID: 26855248.
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  160. Bourgeois FT, Olson KL, Tse T, Ioannidis JP, Mandl KD. Prevalence and Characteristics of Interventional Trials Conducted Exclusively in Elderly Persons: A Cross-Sectional Analysis of Registered Clinical Trials. PLoS One. 2016; 11(5):e0155948. PMID: 27196289.
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  161. Goldstein BA, Navar AM, Pencina MJ, Ioannidis JP. Opportunities and challenges in developing risk prediction models with electronic health records data: a systematic review. J Am Med Inform Assoc. 2017 01; 24(1):198-208. PMID: 27189013.
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  162. Ioannidis JP. We need more randomized trials in nutrition-preferably large, long-term, and with negative results. Am J Clin Nutr. 2016 06; 103(6):1385-6. PMID: 27146649.
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  163. Thombs BD, Benedetti A, Kloda LA, Levis B, Azar M, Riehm KE, Saadat N, Cuijpers P, Gilbody S, Ioannidis JP, McMillan D, Patten SB, Shrier I, Steele RJ, Ziegelstein RC, Loiselle CG, Henry M, Ismail Z, Mitchell N, Tonelli M. Diagnostic accuracy of the Depression subscale of the Hospital Anxiety and Depression Scale (HADS-D) for detecting major depression: protocol for a systematic review and individual patient data meta-analyses. BMJ Open. 2016 Apr 13; 6(4):e011913. PMID: 27075844; PMCID: PMC4838677.
  164. Hemkens LG, Contopoulos-Ioannidis DG, Ioannidis JP. Current use of routinely collected health data to complement randomized controlled trials: a meta-epidemiological survey. CMAJ Open. 2016 Apr-Jun; 4(2):E132-40. PMID: 27398355; PMCID: PMC4933635.
  165. Contopoulos-Ioannidis D, Tseretopoulou X, Ancker M, Walterspiel JN, Panagiotou OA, Maldonado Y, Ioannidis JP. Comparative rates of harms in randomized trials from more developed versus less developed countries may be different. J Clin Epidemiol. 2016 10; 78:10-21. PMID: 27063207.
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  166. Ioannidis JP. Biases in obesity research: Identify, correct, endorse, or abandon effort? Obesity (Silver Spring). 2016 04; 24(4):767-8. PMID: 27028277.
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  167. Ippolito G, Lanini S, Brouqui P, Di Caro A, Vairo F, Fusco FM, Krishna S, Capobianchi MR, Kyobe-Bosa H, Puro V, Wölfel R, Avsic-Zupanc T, Ioannidis JP, Portella G, Kremsner P, Dar O, Bates M, Zumla A. Non-randomised Ebola trials--lessons for optimal outbreak research. Lancet Infect Dis. 2016 Apr; 16(4):407-8. PMID: 27036341.
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  168. Fleming PS, Koletsi D, Ioannidis JP, Pandis N. High quality of the evidence for medical and other health-related interventions was uncommon in Cochrane systematic reviews. J Clin Epidemiol. 2016 10; 78:34-42. PMID: 27032875.
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  169. Lu Y, Ioannidis JP. Transparent Communication of Radiology Research: Reporting Guidelines and Beyond. Acad Radiol. 2016 May; 23(5):529-30. PMID: 27017133.
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  170. Moher D, Goodman SN, Ioannidis JP. Academic criteria for appointment, promotion and rewards in medical research: where's the evidence? Eur J Clin Invest. 2016 May; 46(5):383-5. PMID: 26924551.
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  171. Chavalarias D, Wallach JD, Li AH, Ioannidis JP. Evolution of Reporting P Values in the Biomedical Literature, 1990-2015. JAMA. 2016 Mar 15; 315(11):1141-8. PMID: 26978209.
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  172. Ioannidis JP. Most psychotherapies do not really work, but those that might work should be assessed in biased studies. Epidemiol Psychiatr Sci. 2016 Oct; 25(5):436-438. PMID: 26952766.
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  173. Ioannidis JP. Evidence-based medicine has been hijacked: a report to David Sackett. J Clin Epidemiol. 2016 05; 73:82-6. PMID: 26934549.
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  174. Manrai AK, Ioannidis JP, Kohane IS. Clinical Genomics: From Pathogenicity Claims to Quantitative Risk Estimates. JAMA. 2016 Mar 22-29; 315(12):1233-4. PMID: 26925924.
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  175. Bruns SB, Ioannidis JP. p-Curve and p-Hacking in Observational Research. PLoS One. 2016; 11(2):e0149144. PMID: 26886098; PMCID: PMC4757561.
  176. Ioannidis JP. Commentary: Salt and the assault of opinion on evidence. Int J Epidemiol. 2016 Feb; 45(1):264-5. PMID: 26888871.
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  177. Hemkens LG, Contopoulos-Ioannidis DG, Ioannidis JP. Routinely collected data and comparative effectiveness evidence: promises and limitations. CMAJ. 2016 May 17; 188(8):E158-64. PMID: 26883316; PMCID: PMC4868623 [Available on 05/17/17].
  178. Donadeu FX, Sontakke SD, Ioannidis J. MicroRNA indicators of follicular steroidogenesis. Reprod Fertil Dev. 2016 Feb 11. PMID: 26863388.
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  179. Hemkens LG, Contopoulos-Ioannidis DG, Ioannidis JP. Agreement of treatment effects for mortality from routinely collected data and subsequent randomized trials: meta-epidemiological survey. BMJ. 2016 Feb 08; 352:i493. PMID: 26858277.
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  180. Zorzela L, Loke YK, Ioannidis JP, Golder S, Santaguida P, Altman DG, Moher D, Vohra S. PRISMA harms checklist: improving harms reporting in systematic reviews. BMJ. 2016 Feb 01; 352:i157. PMID: 26830668.
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  181. Iqbal SA, Wallach JD, Khoury MJ, Schully SD, Ioannidis JP. Reproducible Research Practices and Transparency across the Biomedical Literature. PLoS Biol. 2016 Jan; 14(1):e1002333. PMID: 26726926; PMCID: PMC4699702.
  182. Hsing A, Ioannidis JP. Korean National Health Insurance Database--Reply. JAMA Intern Med. 2016 Jan; 176(1):138-9. PMID: 26747668.
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  183. Manrai AK, Patel CJ, Gehlenborg N, Tatonetti NP, Ioannidis JP, Kohane IS. METHODS TO ENHANCE THE REPRODUCIBILITY OF PRECISION MEDICINE. Pac Symp Biocomput. 2016; 21:180-2. PMID: 26776184.
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  184. Manrai AK, Patel CJ, Gehlenborg N, Tatonetti NP, Ioannidis JP, Kohane IS. METHODS TO ENHANCE THE REPRODUCIBILITY OF PRECISION MEDICINE. Pac Symp Biocomput. 2016; 21:180-182. PMID: 28004011.
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  185. Bellou V, Belbasis L, Tzoulaki I, Evangelou E, Ioannidis JP. Environmental risk factors and Parkinson's disease: An umbrella review of meta-analyses. Parkinsonism Relat Disord. 2016 Feb; 23:1-9. PMID: 26739246.
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  186. Kypreou KP, Stefanaki I, Antonopoulou K, Karagianni F, Ntritsos G, Zaras A, Nikolaou V, Kalfa I, Chasapi V, Polydorou D, Gogas H, Spyrou GM, Bertram L, Lill CM, Ioannidis JPA, Antoniou C, Evangelou E, Stratigos AI. Prediction of Melanoma Risk in a Southern European Population Based on a Weighted Genetic Risk Score. J Invest Dermatol. 2016 Mar; 136(3):690-695. PMID: 27015455.
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  187. Ioannidis JP. Exposure-wide epidemiology: revisiting Bradford Hill. Stat Med. 2016 May 20; 35(11):1749-62. PMID: 26646432.
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  188. Flacco ME, Manzoli L, Ioannidis JP. Noninferiority is almost certain with lenient noninferiority margins. J Clin Epidemiol. 2016 Mar; 71:118. PMID: 26607237.
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  189. Manzoli L, Flacco ME, Boccia S, D'Andrea E, Panic N, Marzuillo C, Siliquini R, Ricciardi W, Villari P, Ioannidis JP. Generic versus brand-name drugs used in cardiovascular diseases. Eur J Epidemiol. 2016 04; 31(4):351-68. PMID: 26620809.
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  190. Siontis KC, Ioannidis JPA, Katritsis GD, Noseworthy PA, Packer DL, Hummel JD, Jais P, Krittayaphong R, Mont L, Morillo CA, Nielsen JC, Oral H, Pappone C, Santinelli V, Weerasooriya R, Wilber DJ, Gersh BJ, Josephson ME, Katritsis DG. Radiofrequency Ablation Versus Antiarrhythmic Drug Therapy for Atrial Fibrillation: Meta-Analysis of Quality of Life, Morbidity, and Mortality. JACC Clin Electrophysiol. 2016 Apr; 2(2):170-180. PMID: 29766867.
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  191. Ioannidis JP. Failure to Replicate: Sound the Alarm. Cerebrum. 2015 Nov-Dec; 2015. PMID: 27420921; PMCID: PMC4938249.
  192. Naci H, Ioannidis JP. Comparative effectiveness of exercise and drug interventions on mortality outcomes: metaepidemiological study. Br J Sports Med. 2015 Nov; 49(21):1414-22. PMID: 26476429; PMCID: PMC4680125.
  193. Thombs BD, Benedetti A, Kloda LA, Levis B, Riehm KE, Azar M, Cuijpers P, Gilbody S, Ioannidis JP, McMillan D, Patten SB, Shrier I, Steele RJ, Ziegelstein RC, Tonelli M, Mitchell N, Comeau L, Schinazi J, Vigod S. Diagnostic accuracy of the Edinburgh Postnatal Depression Scale (EPDS) for detecting major depression in pregnant and postnatal women: protocol for a systematic review and individual patient data meta-analyses. BMJ Open. 2015 Oct 20; 5(10):e009742. PMID: 26486977; PMCID: PMC4620163.
  194. Ioannidis JP, Fanelli D, Dunne DD, Goodman SN. Meta-research: Evaluation and Improvement of Research Methods and Practices. PLoS Biol. 2015 Oct; 13(10):e1002264. PMID: 26431313; PMCID: PMC4592065.
  195. Serghiou S, Patel CJ, Tan YY, Koay P, Ioannidis JP. Field-wide meta-analyses of observational associations can map selective availability of risk factors and the impact of model specifications. J Clin Epidemiol. 2016 Mar; 71:58-67. PMID: 26415577.
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  196. Ioannidis J. John Ioannidis: Uncompromising gentle maniac. BMJ. 2015 Sep 24; 351:h4992. PMID: 26404555.
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  197. Ebrahim S, Bance S, Athale A, Malachowski C, Ioannidis JP. Meta-analyses with industry involvement are massively published and report no caveats for antidepressants. J Clin Epidemiol. 2016 Feb; 70:155-63. PMID: 26399904.
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  198. Boccia S, Rothman KJ, Panic N, Flacco ME, Rosso A, Pastorino R, Manzoli L, La Vecchia C, Villari P, Boffetta P, Ricciardi W, Ioannidis JP. Registration practices for observational studies on ClinicalTrials.gov indicated low adherence. J Clin Epidemiol. 2016 Feb; 70:176-82. PMID: 26386325.
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  199. Ioannidis JP. Is It Possible to Recognize a Major Scientific Discovery? JAMA. 2015 Sep 15; 314(11):1135-7. PMID: 26372580.
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  200. Hsing AW, Ioannidis JP. Nationwide Population Science: Lessons From the Taiwan National Health Insurance Research Database. JAMA Intern Med. 2015 Sep; 175(9):1527-9. PMID: 26192815.
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  201. Nalls MA, McLean CY, Rick J, Eberly S, Hutten SJ, Gwinn K, Sutherland M, Martinez M, Heutink P, Williams NM, Hardy J, Gasser T, Brice A, Price TR, Nicolas A, Keller MF, Molony C, Gibbs JR, Chen-Plotkin A, Suh E, Letson C, Fiandaca MS, Mapstone M, Federoff HJ, Noyce AJ, Morris H, Van Deerlin VM, Weintraub D, Zabetian C, Hernandez DG, Lesage S, Mullins M, Conley ED, Northover CA, Frasier M, Marek K, Day-Williams AG, Stone DJ, Ioannidis JP, Singleton AB. Diagnosis of Parkinson's disease on the basis of clinical and genetic classification: a population-based modelling study. Lancet Neurol. 2015 Oct; 14(10):1002-9. PMID: 26271532.
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  202. Naci H, Ioannidis JP. Evaluation of Wellness Determinants and Interventions by Citizen Scientists. JAMA. 2015 Jul 14; 314(2):121-2. PMID: 26068643.
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  203. Ioannidis JP. Anticipating consequences of sharing raw data and code and of awarding badges for sharing. J Clin Epidemiol. 2016 Feb; 70:258-60. PMID: 26163123.
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  204. Goldstein BA, Knowles JW, Salfati E, Ioannidis JP, Assimes TL. Corrigendum: Simple, standardized incorporation of genetic risk into non-genetic risk prediction tools for complex traits: coronary heart disease as an example. Front Genet. 2015; 6:231. PMID: 26217377; PMCID: PMC4493401.
  205. Verghese A, Charlton B, Kassirer JP, Ramsey M, Ioannidis JP. Inadequacies of Physical Examination as a Cause of Medical Errors and Adverse Events: A Collection of Vignettes. Am J Med. 2015 Dec; 128(12):1322-4.e3. PMID: 26144103.
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  206. Siontis KC, Siontis GC, Contopoulos-Ioannidis DG, Ioannidis JP. Reply to letter by Ferrante di Ruffano et al.: Patient outcomes in randomized comparisons of diagnostic tests are still the ultimate judge. J Clin Epidemiol. 2016 Jan; 69:267-8. PMID: 26130596.
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  207. Patel CJ, Burford B, Ioannidis JP. Assessment of vibration of effects due to model specification can demonstrate the instability of observational associations. J Clin Epidemiol. 2015 Sep; 68(9):1046-58. PMID: 26279400; PMCID: PMC4555355.
  208. Hutton B, Salanti G, Caldwell DM, Chaimani A, Schmid CH, Cameron C, Ioannidis JP, Straus S, Thorlund K, Jansen JP, Mulrow C, Catalá-López F, Gøtzsche PC, Dickersin K, Boutron I, Altman DG, Moher D. The PRISMA extension statement for reporting of systematic reviews incorporating network meta-analyses of health care interventions: checklist and explanations. Ann Intern Med. 2015 Jun 02; 162(11):777-84. PMID: 26030634.
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  209. Rhee SY, Blanco JL, Jordan MR, Taylor J, Lemey P, Varghese V, Hamers RL, Bertagnolio S, de Wit TF, Aghokeng AF, Albert J, Avi R, Avila-Rios S, Bessong PO, Brooks JI, Boucher CA, Brumme ZL, Busch MP, Bussmann H, Chaix ML, Chin BS, D'Aquin TT, De Gascun CF, Derache A, Descamps D, Deshpande AK, Djoko CF, Eshleman SH, Fleury H, Frange P, Fujisaki S, Harrigan PR, Hattori J, Holguin A, Hunt GM, Ichimura H, Kaleebu P, Katzenstein D, Kiertiburanakul S, Kim JH, Kim SS, Li Y, Lutsar I, Morris L, Ndembi N, Kee PN, Paranjape RS, Peeters M, Poljak M, Price MA, Ragonnet-Cronin ML, Reyes-Terán G, Rolland M, Sirivichayakul S, Smith DM, Soares MA, Soriano VV, Ssemwanga D, Stanojevic M, Stefani MA, Sugiura W, Sungkanuparph S, Tanuri A, Tee KK, Truong HM, van de Vijver DA, Vidal N, Yang C, Yang R, Yebra G, Ioannidis JP, Vandamme AM, Shafer RW. Correction: Geographic and Temporal Trends in the Molecular Epidemiology and Genetic Mechanisms of Transmitted HIV-1 Drug Resistance: An Individual-Patient- and Sequence-Level Meta-Analysis. PLoS Med. 2015 Jun; 12(6):e1001845. PMID: 26030872; PMCID: PMC4452696.
  210. Karassa FB, Ioannidis JP. Clinical trials: A transparent future for clinical trial reporting. Nat Rev Rheumatol. 2015 Jun; 11(6):324-6. PMID: 25939418.
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  211. Lanini S, Zumla A, Ioannidis JP, Di Caro A, Krishna S, Gostin L, Girardi E, Pletschette M, Strada G, Baritussio A, Portella G, Apolone G, Cavuto S, Satolli R, Kremsner P, Vairo F, Ippolito G. Are adaptive randomised trials or non-randomised studies the best way to address the Ebola outbreak in west Africa? Lancet Infect Dis. 2015 Jun; 15(6):738-45. PMID: 25881871.
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  212. Rhee SY, Blanco JL, Jordan MR, Taylor J, Lemey P, Varghese V, Hamers RL, Bertagnolio S, Rinke de Wit TF, Aghokeng AF, Albert J, Avi R, Avila-Rios S, Bessong PO, Brooks JI, Boucher CA, Brumme ZL, Busch MP, Bussmann H, Chaix ML, Chin BS, D'Aquin TT, De Gascun CF, Derache A, Descamps D, Deshpande AK, Djoko CF, Eshleman SH, Fleury H, Frange P, Fujisaki S, Harrigan PR, Hattori J, Holguin A, Hunt GM, Ichimura H, Kaleebu P, Katzenstein D, Kiertiburanakul S, Kim JH, Kim SS, Li Y, Lutsar I, Morris L, Ndembi N, Ng KP, Paranjape RS, Peeters M, Poljak M, Price MA, Ragonnet-Cronin ML, Reyes-Terán G, Rolland M, Sirivichayakul S, Smith DM, Soares MA, Soriano VV, Ssemwanga D, Stanojevic M, Stefani MA, Sugiura W, Sungkanuparph S, Tanuri A, Tee KK, Truong HM, van de Vijver DA, Vidal N, Yang C, Yang R, Yebra G, Ioannidis JP, Vandamme AM, Shafer RW. Geographic and temporal trends in the molecular epidemiology and genetic mechanisms of transmitted HIV-1 drug resistance: an individual-patient- and sequence-level meta-analysis. PLoS Med. 2015 Apr; 12(4):e1001810. PMID: 25849352; PMCID: PMC4388826.
  213. IntHout J, Ioannidis JP, Borm GF, Goeman JJ. Small studies are more heterogeneous than large ones: a meta-meta-analysis. J Clin Epidemiol. 2015 Aug; 68(8):860-9. PMID: 25959635.
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  214. Djulbegovic B, Hozo I, Ioannidis J. Modern health care as a game theory problem: reply. Eur J Clin Invest. 2015 Apr; 45(4):443. PMID: 25630659.
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  215. Dal-Ré R, Bracken MB, Ioannidis JP. Call to improve transparency of trials of non-regulated interventions. BMJ. 2015 Mar 27; 350:h1323. PMID: 25820265.
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  216. Mischak H, Critselis E, Hanash S, Gallagher WM, Vlahou A, Ioannidis JP. Epidemiologic design and analysis for proteomic studies: a primer on -omic technologies. Am J Epidemiol. 2015 May 01; 181(9):635-47. PMID: 25792606.
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  217. Ioannidis JP. Preventing tooth loss with biannual dental visits and genetic testing: does it work? J Am Dent Assoc. 2015 Mar; 146(3):141-3. PMID: 25726336.
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  218. Ioannidis JP. Translational research may be most successful when it fails. Hastings Cent Rep. 2015 Mar-Apr; 45(2):39-40. PMID: 25739779.
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  219. Koretz RL, Lin KW, Ioannidis JP, Lenzer J. Authors' reply to Selvapatt and colleagues, Matthews and colleagues, Badrinath, and Ward and Lee. BMJ. 2015 Feb 24; 350:h674. PMID: 25711896.
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  220. Koretz RL, Lin KW, Ioannidis JP, Lenzer J. Authors' reply to Foster and colleagues. BMJ. 2015 Feb 24; 350:h1000. PMID: 25711887.
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  221. Ioannidis JP. Stealth research: is biomedical innovation happening outside the peer-reviewed literature? JAMA. 2015 Feb 17; 313(7):663-4. PMID: 25688775.
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  222. Tsilidis KK, Ioannidis JP. Authors' reply to editorial linked to their umbrella review of meta-analyses of observational studies on type 2 diabetes and cancer. BMJ. 2015 Feb 11; 350:h711. PMID: 25673332.
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  223. Flacco ME, Manzoli L, Boccia S, Capasso L, Aleksovska K, Rosso A, Scaioli G, De Vito C, Siliquini R, Villari P, Ioannidis JP. Head-to-head randomized trials are mostly industry sponsored and almost always favor the industry sponsor. J Clin Epidemiol. 2015 Jul; 68(7):811-20. PMID: 25748073.
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  224. Belbasis L, Bellou V, Evangelou E, Ioannidis JP, Tzoulaki I. Environmental risk factors and multiple sclerosis: an umbrella review of systematic reviews and meta-analyses. Lancet Neurol. 2015 Mar; 14(3):263-73. PMID: 25662901.
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  225. Siontis GC, Ioannidis JP. Response to letter by Forike et al.: more rigorous, not less, external validation is needed. J Clin Epidemiol. 2016 Jan; 69:250-1. PMID: 25724895.
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  226. Ioannidis JP, Horbar JD, Ovelman CM, Brosseau Y, Thorlund K, Buus-Frank ME, Mills EJ, Soll RF. Completeness of main outcomes across randomized trials in entire discipline: survey of chronic lung disease outcomes in preterm infants. BMJ. 2015 Jan 26; 350:h72. PMID: 25623087.
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  227. Lara-Pezzi E, Menasché P, Trouvin JH, Badimón L, Ioannidis JP, Wu JC, Hill JA, Koch WJ, De Felice AF, de Waele P, Steenwinckel V, Hajjar RJ, Zeiher AM. Guidelines for translational research in heart failure. J Cardiovasc Transl Res. 2015 Feb; 8(1):3-22. PMID: 25604959.
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  228. Saquib N, Saquib J, Ioannidis JP. Does screening for disease save lives in asymptomatic adults? Systematic review of meta-analyses and randomized trials. Int J Epidemiol. 2015 Feb; 44(1):264-77. PMID: 25596211.
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  229. Patel CJ, Ioannidis JP, Cullen MR, Rehkopf DH. Systematic assessment of the correlations of household income with infectious, biochemical, physiological, and environmental factors in the United States, 1999-2006. Am J Epidemiol. 2015 Feb 01; 181(3):171-9. PMID: 25589242; PMCID: PMC4312426.
  230. Koretz RL, Lin KW, Ioannidis JP, Lenzer J. Is widespread screening for hepatitis C justified? BMJ. 2015 Jan 13; 350:g7809. PMID: 25587052.
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  231. Moons KG, Altman DG, Reitsma JB, Ioannidis JP, Macaskill P, Steyerberg EW, Vickers AJ, Ransohoff DF, Collins GS. Transparent Reporting of a multivariable prediction model for Individual Prognosis or Diagnosis (TRIPOD): explanation and elaboration. Ann Intern Med. 2015 Jan 06; 162(1):W1-73. PMID: 25560730.
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  232. Ebrahim S, Ioannidis JP. Reanalyses of trial results--reply. JAMA. 2015 Jan 06; 313(1):93. PMID: 25562278.
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  233. Tsilidis KK, Kasimis JC, Lopez DS, Ntzani EE, Ioannidis JP. Type 2 diabetes and cancer: umbrella review of meta-analyses of observational studies. BMJ. 2015 Jan 02; 350:g7607. PMID: 25555821.
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  234. Begley CG, Ioannidis JP. Reproducibility in science: improving the standard for basic and preclinical research. Circ Res. 2015 Jan 02; 116(1):116-26. PMID: 25552691.
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  235. Djulbegovic B, Hozo I, Ioannidis JP. Modern health care as a game theory problem. Eur J Clin Invest. 2015 Jan; 45(1):1-12. PMID: 25413314.
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  236. Ioannidis JP. Handling the fragile vase of scientific practices. Addiction. 2015 Jan; 110(1):9-10. PMID: 25515825.
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  237. Banglawala SM, Lawrence LA, Franko-Tobin E, Soler ZM, Schlosser RJ, Ioannidis J. Recent randomized controlled trials in otolaryngology. Otolaryngol Head Neck Surg. 2015 Mar; 152(3):418-23. PMID: 25550226.
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  238. Ioannidis JP. Clinical trials: what a waste. BMJ. 2014 Dec 10; 349:g7089. PMID: 25499097.
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  239. Ioannidis J, Ashworth C, Raue R, Donadeu X. 103 CIRCULATING microRNAs FOR EARLY DIAGNOSIS OF BOVINE PREGNANCY. Reprod Fertil Dev. 2014 Dec; 27(1):144-5. PMID: 25472152.
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  240. Khoury MJ, Ioannidis JP. Medicine. Big data meets public health. Science. 2014 Nov 28; 346(6213):1054-5. PMID: 25430753; PMCID: PMC4684636.
  241. Papatheodorou SI, Tsilidis KK, Evangelou E, Ioannidis JP. Application of credibility ceilings probes the robustness of meta-analyses of biomarkers and cancer risk. J Clin Epidemiol. 2015 Feb; 68(2):163-74. PMID: 25433443.
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  242. Ioannidis JP. A generalized view of self-citation: direct, co-author, collaborative, and coercive induced self-citation. J Psychosom Res. 2015 Jan; 78(1):7-11. PMID: 25466321.
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  243. Antonopoulou K, Stefanaki I, Lill CM, Chatzinasiou F, Kypreou KP, Karagianni F, Athanasiadis E, Spyrou GM, Ioannidis JPA, Bertram L, Evangelou E, Stratigos AJ. Updated field synopsis and systematic meta-analyses of genetic association studies in cutaneous melanoma: the MelGene database. J Invest Dermatol. 2015 Apr; 135(4):1074-1079. PMID: 25407435.
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  244. Athanasiadis EI, Antonopoulou K, Chatzinasiou F, Lill CM, Bourdakou MM, Sakellariou A, Kypreou K, Stefanaki I, Evangelou E, Ioannidis JP, Bertram L, Stratigos AJ, Spyrou GM. A Web-based database of genetic association studies in cutaneous melanoma enhanced with network-driven data exploration tools. Database (Oxford). 2014; 2014. PMID: 25380778; PMCID: PMC4224266.
  245. Ioannidis JP, Boyack KW, Small H, Sorensen AA, Klavans R. Bibliometrics: Is your most cited work your best? Nature. 2014 Oct 30; 514(7524):561-2. PMID: 25355346.
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  246. Thombs BD, Benedetti A, Kloda LA, Levis B, Nicolau I, Cuijpers P, Gilbody S, Ioannidis JP, McMillan D, Patten SB, Shrier I, Steele RJ, Ziegelstein RC. The diagnostic accuracy of the Patient Health Questionnaire-2 (PHQ-2), Patient Health Questionnaire-8 (PHQ-8), and Patient Health Questionnaire-9 (PHQ-9) for detecting major depression: protocol for a systematic review and individual patient data meta-analyses. Syst Rev. 2014 Oct 27; 3:124. PMID: 25348422; PMCID: PMC4218786.
  247. Siontis GC, Tzoulaki I, Castaldi PJ, Ioannidis JP. External validation of new risk prediction models is infrequent and reveals worse prognostic discrimination. J Clin Epidemiol. 2015 Jan; 68(1):25-34. PMID: 25441703.
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  248. Chang CQ, Tingle SR, Filipski KK, Khoury MJ, Lam TK, Schully SD, Ioannidis JP. An overview of recommendations and translational milestones for genomic tests in cancer. Genet Med. 2015 Jun; 17(6):431-40. PMID: 25341115; PMCID: PMC4686861.
  249. Ioannidis JP. How to make more published research true. PLoS Med. 2014 Oct; 11(10):e1001747. PMID: 25334033; PMCID: PMC4204808.
  250. Trinquart L, Ioannidis JP, Chatellier G, Ravaud P. A test for reporting bias in trial networks: simulation and case studies. BMC Med Res Methodol. 2014 Sep 27; 14:112. PMID: 25262204; PMCID: PMC4193287.
  251. Ebrahim S, Sohani ZN, Montoya L, Agarwal A, Thorlund K, Mills EJ, Ioannidis JP. Reanalyses of randomized clinical trial data. JAMA. 2014 Sep 10; 312(10):1024-32. PMID: 25203082.
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  252. Brown AW, Ioannidis JP, Cope MB, Bier DM, Allison DB. Unscientific beliefs about scientific topics in nutrition. Adv Nutr. 2014 Sep; 5(5):563-5. PMID: 25469397; PMCID: PMC4188234.
  253. Gwinn M, Ioannidis JP, Little J, Khoury MJ. Editorial: Updated guidance on human genome epidemiology (HuGE) reviews and meta-analyses of genetic associations. Am J Epidemiol. 2014 Sep 15; 180(6):559-61. PMID: 25164421.
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  254. Naci H, Ioannidis JP. How good is "evidence" from clinical studies of drug effects and why might such evidence fail in the prediction of the clinical utility of drugs? Annu Rev Pharmacol Toxicol. 2015; 55:169-89. PMID: 25149917.
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  255. Ioannidis JP, Khoury MJ. Assessing value in biomedical research: the PQRST of appraisal and reward. JAMA. 2014 Aug 06; 312(5):483-4. PMID: 24911291; PMCID: PMC4687964.
  256. Goldstein BA, Knowles JW, Salfati E, Ioannidis JP, Assimes TL. Simple, standardized incorporation of genetic risk into non-genetic risk prediction tools for complex traits: coronary heart disease as an example. Front Genet. 2014; 5:254. PMID: 25136350; PMCID: PMC4117937.
  257. Nalls MA, Pankratz N, Lill CM, Do CB, Hernandez DG, Saad M, DeStefano AL, Kara E, Bras J, Sharma M, Schulte C, Keller MF, Arepalli S, Letson C, Edsall C, Stefansson H, Liu X, Pliner H, Lee JH, Cheng R, Ikram MA, Ioannidis JP, Hadjigeorgiou GM, Bis JC, Martinez M, Perlmutter JS, Goate A, Marder K, Fiske B, Sutherland M, Xiromerisiou G, Myers RH, Clark LN, Stefansson K, Hardy JA, Heutink P, Chen H, Wood NW, Houlden H, Payami H, Brice A, Scott WK, Gasser T, Bertram L, Eriksson N, Foroud T, Singleton AB. Large-scale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson's disease. Nat Genet. 2014 Sep; 46(9):989-93. PMID: 25064009.
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  258. Ramos YF, Metrustry S, Arden N, Bay-Jensen AC, Beekman M, de Craen AJ, Cupples LA, Esko T, Evangelou E, Felson DT, Hart DJ, Ioannidis JP, Karsdal M, Kloppenburg M, Lafeber F, Metspalu A, Panoutsopoulou K, Slagboom PE, Spector TD, van Spil EW, Uitterlinden AG, Zhu Y, Valdes AM, van Meurs JB, Meulenbelt I. Meta-analysis identifies loci affecting levels of the potential osteoarthritis biomarkers sCOMP and uCTX-II with genome wide significance. J Med Genet. 2014 Sep; 51(9):596-604. PMID: 25057126.
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  259. Ioannidis JP. Modeling and research on research. Clin Chem. 2014 Sep; 60(9):1238-9. PMID: 25037936.
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  260. Fleurence RL, Forsythe LP, Lauer M, Rotter J, Ioannidis JP, Beal A, Frank L, Selby JV. Engaging patients and stakeholders in research proposal review: the patient-centered outcomes research institute. Ann Intern Med. 2014 Jul 15; 161(2):122-30. PMID: 25023251.
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  261. Ioannidis JP, Boyack KW, Klavans R. Estimates of the continuously publishing core in the scientific workforce. PLoS One. 2014; 9(7):e101698. PMID: 25007173; PMCID: PMC4090124.
  262. Murad MH, Montori VM, Ioannidis JP, Jaeschke R, Devereaux PJ, Prasad K, Neumann I, Carrasco-Labra A, Agoritsas T, Hatala R, Meade MO, Wyer P, Cook DJ, Guyatt G. How to read a systematic review and meta-analysis and apply the results to patient care: users' guides to the medical literature. JAMA. 2014 Jul; 312(2):171-9. PMID: 25005654.
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  263. Tzoulaki I, Ebbels TM, Valdes A, Elliott P, Ioannidis JP. Design and analysis of metabolomics studies in epidemiologic research: a primer on -omic technologies. Am J Epidemiol. 2014 Jul 15; 180(2):129-39. PMID: 24966222.
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  264. Nair VS, Pritchard CC, Tewari M, Ioannidis JP. Design and Analysis for Studying microRNAs in Human Disease: A Primer on -Omic Technologies. Am J Epidemiol. 2014 Jul 15; 180(2):140-52. PMID: 24966218; PMCID: PMC4082346.
  265. Zintzaras E, Ioannidis JP. HELOW: a program for testing extreme homogeneity in meta-analysis. Comput Methods Programs Biomed. 2014 Nov; 117(2):383-6. PMID: 25023534.
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  266. Patel CJ, Ioannidis JP. Placing epidemiological results in the context of multiplicity and typical correlations of exposures. J Epidemiol Community Health. 2014 Nov; 68(11):1096-100. PMID: 24923805; PMCID: PMC4545966.
  267. Tsilidis KK, Capothanassi D, Allen NE, Rizos EC, Lopez DS, van Veldhoven K, Sacerdote C, Ashby D, Vineis P, Tzoulaki I, Ioannidis JP. Metformin does not affect cancer risk: a cohort study in the U.K. Clinical Practice Research Datalink analyzed like an intention-to-treat trial. Diabetes Care. 2014 Sep; 37(9):2522-32. PMID: 24898303.
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  268. Ioannidis JP. Guidelines for cardiovascular risk assessment and cholesterol treatment--reply. JAMA. 2014 Jun 04; 311(21):2235-6. PMID: 24893099.
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  269. Patel CJ, Ioannidis JP. Studying the elusive environment in large scale. JAMA. 2014 Jun 04; 311(21):2173-4. PMID: 24893084; PMCID: PMC4110965.
  270. Ioannidis JP. Errors (my very own) and the fearful uncertainty of numbers. Eur J Clin Invest. 2014 Jul; 44(7):617-8. PMID: 24785138.
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  271. Rifai N, Bossuyt PM, Ioannidis JP, Bray KR, McShane LM, Golub RM, Hooft L. Registering diagnostic and prognostic trials of tests: is it the right thing to do? Clin Chem. 2014 Sep; 60(9):1146-52. PMID: 24855278.
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  272. Ioannidis JP, Hozo I, Djulbegovic B. Study design and the drug development process--reply. JAMA. 2014 May 21; 311(19):2023-4. PMID: 24846045.
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  273. Sigounas DE, Christodoulou DK, Karamoutsios A, Tatsioni A, Dova L, Vartholomatos G, Kolaitis N, Katsanos KH, Zervou E, Ioannidis JP, Tsianos EV. Changes of serum adhesion molecules and cytokines in post-ERCP pancreatitis: adhesion molecules and cytokines in acute pancreatitis. Clin Biochem. 2014 Sep; 47(13-14):1245-9. PMID: 24845714.
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  274. Manzoli L, Flacco ME, D'Addario M, Capasso L, De Vito C, Marzuillo C, Villari P, Ioannidis JP. Non-publication and delayed publication of randomized trials on vaccines: survey. BMJ. 2014 May 16; 348:g3058. PMID: 24838102.
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  275. Di Meo A, Diamandis EP, Rodriguez H, Hoofnagle AN, Ioannidis J, Lopez M. What is wrong with clinical proteomics? Clin Chem. 2014 Oct; 60(10):1258-66. PMID: 24831563.
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  276. Theodoratou E, Ioannidis JP. Authors' reply to Boucher. BMJ. 2014 Apr 29; 348:g2927. PMID: 24780520.
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  277. Ioannidis JP, Mullard A. John P. A. Ioannidis. Nat Rev Drug Discov. 2014 May; 13(5):328-9. PMID: 24751817.
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  278. Kaw R, Pasupuleti V, Wayne Overby D, Deshpande A, Coleman CI, Ioannidis JP, Hernandez AV. Inferior vena cava filters and postoperative outcomes in patients undergoing bariatric surgery: a meta-analysis. Surg Obes Relat Dis. 2014 Jul-Aug; 10(4):725-33. PMID: 25224168.
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  279. Ashbury FD, Little J, Ioannidis JP, Kreiger N, Palmer LJ, Relton C, Taylor P. A vision for chronic disease prevention intervention research: report from a workshop. Can J Public Health. 2014 Apr 17; 105(2):e150-3. PMID: 24886853.
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  280. Theodoratou E, Tzoulaki I, Zgaga L, Ioannidis JP. Vitamin D and multiple health outcomes: umbrella review of systematic reviews and meta-analyses of observational studies and randomised trials. BMJ. 2014 Apr 01; 348:g2035. PMID: 24690624.
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  281. Evans JA, Shim JM, Ioannidis JP. Attention to local health burden and the global disparity of health research. PLoS One. 2014; 9(4):e90147. PMID: 24691431.
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  282. Rodriguez-Fontenla C, Calaza M, Evangelou E, Valdes AM, Arden N, Blanco FJ, Carr A, Chapman K, Deloukas P, Doherty M, Esko T, Garcés Aletá CM, Gomez-Reino Carnota JJ, Helgadottir H, Hofman A, Jonsdottir I, Kerkhof HJ, Kloppenburg M, McCaskie A, Ntzani EE, Ollier WE, Oreiro N, Panoutsopoulou K, Ralston SH, Ramos YF, Riancho JA, Rivadeneira F, Slagboom PE, Styrkarsdottir U, Thorsteinsdottir U, Thorleifsson G, Tsezou A, Uitterlinden AG, Wallis GA, Wilkinson JM, Zhai G, Zhu Y, Felson DT, Ioannidis JP, Loughlin J, Metspalu A, Meulenbelt I, Stefansson K, van Meurs JB, Zeggini E, Spector TD, Gonzalez A. Assessment of osteoarthritis candidate genes in a meta-analysis of nine genome-wide association studies. Arthritis Rheumatol. 2014 Apr; 66(4):940-9. PMID: 24757145.
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  283. Glasziou P, Macleod M, Chalmers I, Ioannidis JP, Al-Shahi Salman R, Chan AW. Research: increasing value, reducing waste - Authors' reply. Lancet. 2014 Mar 29; 383(9923):1126-7. PMID: 24679627.
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  284. Siontis KC, Siontis GC, Contopoulos-Ioannidis DG, Ioannidis JP. Diagnostic tests often fail to lead to changes in patient outcomes. J Clin Epidemiol. 2014 Jun; 67(6):612-21. PMID: 24679598.
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  285. Tonelli AR, Zein J, Adams J, Ioannidis JP. Effects of interventions on survival in acute respiratory distress syndrome: an umbrella review of 159 published randomized trials and 29 meta-analyses. Intensive Care Med. 2014 Jun; 40(6):769-87. PMID: 24667919; PMCID: PMC4031289.
  286. Ioannidis JP, Munafò MR, Fusar-Poli P, Nosek BA, David SP. Publication and other reporting biases in cognitive sciences: detection, prevalence, and prevention. Trends Cogn Sci. 2014 May; 18(5):235-41. PMID: 24656991; PMCID: PMC4078993.
  287. Kappagoda S, Ioannidis JP. Prevention and control of neglected tropical diseases: overview of randomized trials, systematic reviews and meta-analyses. Bull World Health Organ. 2014 May 01; 92(5):356-366C. PMID: 24839325; PMCID: PMC4007126.
  288. Dewey FE, Grove ME, Pan C, Goldstein BA, Bernstein JA, Chaib H, Merker JD, Goldfeder RL, Enns GM, David SP, Pakdaman N, Ormond KE, Caleshu C, Kingham K, Klein TE, Whirl-Carrillo M, Sakamoto K, Wheeler MT, Butte AJ, Ford JM, Boxer L, Ioannidis JP, Yeung AC, Altman RB, Assimes TL, Snyder M, Ashley EA, Quertermous T. Clinical interpretation and implications of whole-genome sequencing. JAMA. 2014 Mar 12; 311(10):1035-45. PMID: 24618965.
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  289. Lathyris D, Panagiotou OA, Baltogianni M, Ioannidis JP, Contopoulos-Ioannidis DG. Safety of medical interventions in children versus adults. Pediatrics. 2014 Mar; 133(3):e666-73. PMID: 24567023.
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  290. Dal-Ré R, Ioannidis JP, Bracken MB, Buffler PA, Chan AW, Franco EL, La Vecchia C, Weiderpass E. Making prospective registration of observational research a reality. Sci Transl Med. 2014 Feb 19; 6(224):224cm1. PMID: 24553383.
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  291. Fanelli D, Ioannidis JP. Reply to Nuijten et al.: Reanalyses actually confirm that US studies overestimate effects in softer research. Proc Natl Acad Sci U S A. 2014 Feb 18; 111(7):E714-5. PMID: 24693543; PMCID: PMC3932901.
  292. IntHout J, Ioannidis JP, Borm GF. The Hartung-Knapp-Sidik-Jonkman method for random effects meta-analysis is straightforward and considerably outperforms the standard DerSimonian-Laird method. BMC Med Res Methodol. 2014 Feb 18; 14:25. PMID: 24548571; PMCID: PMC4015721.
  293. Tzoulaki I, Seretis A, Ntzani EE, Ioannidis JP. Mapping the expanded often inappropriate use of the Framingham Risk Score in the medical literature. J Clin Epidemiol. 2014 May; 67(5):571-7. PMID: 24513280.
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  294. Ioannidis JP. More than a billion people taking statins?: Potential implications of the new cardiovascular guidelines. JAMA. 2014 Feb 05; 311(5):463-4. PMID: 24296612.
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  295. Oei L, Estrada K, Duncan EL, Christiansen C, Liu CT, Langdahl BL, Obermayer-Pietsch B, Riancho JA, Prince RL, van Schoor NM, McCloskey E, Hsu YH, Evangelou E, Ntzani E, Evans DM, Alonso N, Husted LB, Valero C, Hernandez JL, Lewis JR, Kaptoge SK, Zhu K, Cupples LA, Medina-Gómez C, Vandenput L, Kim GS, Hun Lee S, Castaño-Betancourt MC, Oei EH, Martinez J, Daroszewska A, van der Klift M, Mellström D, Herrera L, Karlsson MK, Hofman A, Ljunggren Ö, Pols HA, Stolk L, van Meurs JB, Ioannidis JP, Zillikens MC, Lips P, Karasik D, Uitterlinden AG, Styrkarsdottir U, Brown MA, Koh JM, Richards JB, Reeve J, Ohlsson C, Ralston SH, Kiel DP, Rivadeneira F. Genome-wide association study for radiographic vertebral fractures: a potential role for the 16q24 BMD locus. Bone. 2014 Feb; 59:20-7. PMID: 24516880.
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  296. Kanters S, Mills EJ, Thorlund K, Bucher HC, Ioannidis JP. Antiretroviral therapy for initial human immunodeficiency virus/AIDS treatment: critical appraisal of the evidence from over 100 randomized trials and 400 systematic reviews and meta-analyses. Clin Microbiol Infect. 2014 Feb; 20(2):114-22. PMID: 24274661.
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  297. Kim DD, Tang JY, Ioannidis JP. Network geometry shows evidence sequestration for medical vs. surgical practices: treatments for basal cell carcinoma. J Clin Epidemiol. 2014 Apr; 67(4):391-400. PMID: 24491794.
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  298. Ioannidis JP. Research accomplishments that are too good to be true: reply to Ting. Intensive Care Med. 2014 Mar; 40(3):468. PMID: 24477457.
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  299. Thombs BD, Ziegelstein RC, Roseman M, Kloda LA, Ioannidis JP. There are no randomized controlled trials that support the United States Preventive Services Task Force Guideline on screening for depression in primary care: a systematic review. BMC Med. 2014 Jan 28; 12:13. PMID: 24472580; PMCID: PMC3922694.
  300. Ioannidis JP, Greenland S, Hlatky MA, Khoury MJ, Macleod MR, Moher D, Schulz KF, Tibshirani R. Increasing value and reducing waste in research design, conduct, and analysis. Lancet. 2014 Jan 11; 383(9912):166-75. PMID: 24411645; PMCID: PMC4697939.
  301. Macleod MR, Michie S, Roberts I, Dirnagl U, Chalmers I, Ioannidis JP, Al-Shahi Salman R, Chan AW, Glasziou P. Biomedical research: increasing value, reducing waste. Lancet. 2014 Jan 11; 383(9912):101-4. PMID: 24411643.
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  302. Iglesias AI, Mihaescu R, Ioannidis JP, Khoury MJ, Little J, van Duijn CM, Janssens AC. Scientific reporting is suboptimal for aspects that characterize genetic risk prediction studies: a review of published articles based on the Genetic RIsk Prediction Studies statement. J Clin Epidemiol. 2014 May; 67(5):487-99. PMID: 24411311.
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  303. Chalmers I, Bracken MB, Djulbegovic B, Garattini S, Grant J, Gülmezoglu AM, Howells DW, Ioannidis JP, Oliver S. How to increase value and reduce waste when research priorities are set. Lancet. 2014 Jan 11; 383(9912):156-65. PMID: 24411644.
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  304. Prasad V, Ioannidis JP. Evidence-based de-implementation for contradicted, unproven, and aspiring healthcare practices. Implement Sci. 2014 Jan 08; 9:1. PMID: 24398253; PMCID: PMC3892018.
  305. Djulbegovic B, Hozo I, Ioannidis JP. Improving the drug development process: more not less randomized trials. JAMA. 2014 Jan 22-29; 311(4):355-6. PMID: 24449311.
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  306. Sun X, Ioannidis JP, Agoritsas T, Alba AC, Guyatt G. How to use a subgroup analysis: users' guide to the medical literature. JAMA. 2014 Jan 22-29; 311(4):405-11. PMID: 24449319.
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  307. Oei L, Hsu YH, Styrkarsdottir U, Eussen BH, de Klein A, Peters MJ, Halldorsson B, Liu CT, Alonso N, Kaptoge SK, Thorleifsson G, Hallmans G, Hocking LJ, Husted LB, Jameson KA, Kruk M, Lewis JR, Patel MS, Scollen S, Svensson O, Trompet S, van Schoor NM, Zhu K, Buckley BM, Cooper C, Ford I, Goltzman D, González-Macías J, Langdahl BL, Leslie WD, Lips P, Lorenc RS, Olmos JM, Pettersson-Kymmer U, Reid DM, Riancho JA, Slagboom PE, Garcia-Ibarbia C, Ingvarsson T, Johannsdottir H, Luben R, Medina-Gómez C, Arp P, Nandakumar K, Palsson ST, Sigurdsson G, van Meurs JB, Zhou Y, Hofman A, Jukema JW, Pols HA, Prince RL, Cupples LA, Marshall CR, Pinto D, Sato D, Scherer SW, Reeve J, Thorsteinsdottir U, Karasik D, Richards JB, Stefansson K, Uitterlinden AG, Ralston SH, Ioannidis JP, Kiel DP, Rivadeneira F, Estrada K. A genome-wide copy number association study of osteoporotic fractures points to the 6p25.1 locus. J Med Genet. 2014 Feb; 51(2):122-31. PMID: 24343915.
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  308. Patel CJ, Rehkopf DH, Leppert JT, Bortz WM, Cullen MR, Chertow GM, Ioannidis JP. Systematic evaluation of environmental and behavioural factors associated with all-cause mortality in the United States national health and nutrition examination survey. Int J Epidemiol. 2013 Dec; 42(6):1795-810. PMID: 24345851; PMCID: PMC3887569.
  309. Bourgeois FT, Olson KL, Ioannidis JP, Mandl KD. Association between pediatric clinical trials and global burden of disease. Pediatrics. 2014 Jan; 133(1):78-87. PMID: 24344112; PMCID: PMC3876184.
  310. Ioannidis JP, Zhou Y, Chang CQ, Schully SD, Khoury MJ, Freedman AN. Potential increased risk of cancer from commonly used medications: an umbrella review of meta-analyses. Ann Oncol. 2014 Jan; 25(1):16-23. PMID: 24310915; PMCID: PMC3868319.
  311. Tonelli AR, Zein J, Ioannidis JP. Geometry of the randomized evidence for treatments of pulmonary hypertension. Cardiovasc Ther. 2013 Dec; 31(6):e138-46. PMID: 24112824; PMCID: PMC4480770.
  312. Doshi P, Goodman SN, Ioannidis JP. Raw data from clinical trials: within reach? Trends Pharmacol Sci. 2013 Dec; 34(12):645-7. PMID: 24295825.
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  313. Gordon AS, Tabor HK, Johnson AD, Snively BM, Assimes TL, Auer PL, Ioannidis JP, Peters U, Robinson JG, Sucheston LE, Wang D, Sotoodehnia N, Rotter JI, Psaty BM, Jackson RD, Herrington DM, O'Donnell CJ, Reiner AP, Rich SS, Rieder MJ, Bamshad MJ, Nickerson DA. Quantifying rare, deleterious variation in 12 human cytochrome P450 drug-metabolism genes in a large-scale exome dataset. Hum Mol Genet. 2014 Apr 15; 23(8):1957-63. PMID: 24282029; PMCID: PMC3959810.
  314. Ioannidis JP. Implausible results in human nutrition research. BMJ. 2013 Nov 14; 347:f6698. PMID: 24231028.
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  315. Matheson GO, Klügl M, Engebretsen L, Bendiksen F, Blair SN, Börjesson M, Budgett R, Derman W, Erdener U, Ioannidis JP, Khan KM, Martinez R, Van Mechelen W, Mountjoy M, Sallis RE, Schwellnus M, Shultz R, Soligard T, Steffen K, Sundberg CJ, Weiler R, Ljungqvist A. Prevention and management of non-communicable disease: the IOC consensus statement, Lausanne 2013. Br J Sports Med. 2013 Nov; 47(16):1003-11. PMID: 24115479.
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  316. Matheson GO, Klügl M, Engebretsen L, Bendiksen F, Blair SN, Börjesson M, Budgett R, Derman W, Erdener U, Ioannidis JP, Khan KM, Martinez R, van Mechelen W, Mountjoy M, Sallis RE, Schwellnus M, Shultz R, Soligard T, Steffen K, Sundberg CJ, Weiler R, Ljungqvist A. Prevention and management of non-communicable disease: the IOC consensus statement, Lausanne 2013. Sports Med. 2013 Nov; 43(11):1075-88. PMID: 24129783.
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  317. Matheson GO, Klügl M, Engebretsen L, Bendiksen F, Blair SN, Börjesson M, Budgett R, Derman W, Erdener U, Ioannidis JP, Khan KM, Martinez R, van Mechelen W, Mountjoy M, Sallis RE, Schwellnus M, Shultz R, Soligard T, Steffen K, Sundberg CJ, Weiler R, Ljungqvist A. Prevention and management of noncommunicable disease: the IOC Consensus Statement, Lausanne 2013. Clin J Sport Med. 2013 Nov; 23(6):419-29. PMID: 24169298.
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  318. Oei L, Estrada K, Duncan EL, Christiansen C, Liu CT, Langdahl BL, Obermayer-Pietsch B, Riancho JA, Prince RL, van Schoor NM, McCloskey E, Hsu YH, Evangelou E, Ntzani E, Evans DM, Alonso N, Husted LB, Valero C, Hernandez JL, Lewis JR, Kaptoge SK, Zhu K, Cupples LA, Medina-Gómez C, Vandenput L, Kim GS, Lee SH, Castaño-Betancourt MC, Oei EH, Martinez J, Daroszewska A, van der Klift M, Mellström D, Herrera L, Karlsson MK, Hofman A, Ljunggren O, Pols HA, Stolk L, van Meurs JB, Ioannidis JP, Zillikens MC, Lips P, Karasik D, Uitterlinden AG, Styrkarsdottir U, Brown MA, Koh JM, Richards JB, Reeve J, Ohlsson C, Ralston SH, Kiel DP, Rivadeneira F. Genome-wide Association Study for Radiographic Vertebral Fractures: A Potential Role for the 16q24 BMD Locus versus Lessons Learned from Challenging Phenotype Definition. Bone. 2013 Oct 25. PMID: 24513584.
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  319. Button KS, Ioannidis JP, Mokrysz C, Nosek BA, Flint J, Robinson ES, Munafò MR. Empirical evidence for low reproducibility indicates low pre-study odds. Nat Rev Neurosci. 2013 Dec; 14(12):877. PMID: 24149186.
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  320. Boyack KW, Klavans R, Sorensen AA, Ioannidis JP. A list of highly influential biomedical researchers, 1996-2011. Eur J Clin Invest. 2013 Dec; 43(12):1339-65. PMID: 24134636.
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  321. Hemkens LG, Contopoulos-Ioannidis DG, Ioannidis JP. Concordance of effects of medical interventions on hospital admission and readmission rates with effects on mortality. CMAJ. 2013 Dec 10; 185(18):E827-37. PMID: 24144601; PMCID: PMC3855143.
  322. Ioannidis JP. Research accomplishments that are too good to be true. Intensive Care Med. 2014 Jan; 40(1):99-101. PMID: 24129497.
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  323. Ioannidis JP, Henriksen L, Prochaska JJ. Endgame: engaging the tobacco industry in its own elimination. Eur J Clin Invest. 2013 Dec; 43(12):1366-70. PMID: 24117211; PMCID: PMC4038649.
  324. Fusar-Poli P, Radua J, Frascarelli M, Mechelli A, Borgwardt S, Di Fabio F, Biondi M, Ioannidis JP, David SP. Evidence of reporting biases in voxel-based morphometry (VBM) studies of psychiatric and neurological disorders. Hum Brain Mapp. 2014 Jul; 35(7):3052-65. PMID: 24123491.
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  325. Naci H, Ioannidis JP. Comparative effectiveness of exercise and drug interventions on mortality outcomes: metaepidemiological study. BMJ. 2013 Oct 01; 347:f5577. PMID: 24473061; PMCID: PMC3788175.
  326. Ioannidis JP. In reply II-reversal of medical practices. Mayo Clin Proc. 2013 Oct; 88(10):1184. PMID: 24079693.
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  327. Ioannidis JP. Discussion: Why "An estimate of the science-wise false discovery rate and application to the top medical literature" is false. Biostatistics. 2014 Jan; 15(1):28-36; discussion 39-45. PMID: 24068251.
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  328. Ioannidis JP. Appropriate vs clinically useful diagnostic tests. JAMA Intern Med. 2013 Sep 23; 173(17):1607-9. PMID: 23877418.
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  329. Lenzer J, Hoffman JR, Furberg CD, Ioannidis JP. Ensuring the integrity of clinical practice guidelines: a tool for protecting patients. BMJ. 2013 Sep 17; 347:f5535. PMID: 24046286.
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  330. Burgio MR, Ioannidis JP, Kaminski BM, Derycke E, Rogers S, Khoury MJ, Seminara D. Collaborative cancer epidemiology in the 21st century: the model of cancer consortia. Cancer Epidemiol Biomarkers Prev. 2013 Dec; 22(12):2148-60. PMID: 24045926.
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  331. Mills EJ, Kanters S, Thorlund K, Chaimani A, Veroniki AA, Ioannidis JP. The effects of excluding treatments from network meta-analyses: survey. BMJ. 2013 Sep 05; 347:f5195. PMID: 24009242; PMCID: PMC3763846.
  332. Ioannidis JP, Karassa FB, Druyts E, Thorlund K, Mills EJ. Biologic agents in rheumatology: unmet issues after 200 trials and $200 billion sales. Nat Rev Rheumatol. 2013 Nov; 9(11):665-73. PMID: 23999553.
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  333. Evangelou E, Kerkhof HJ, Styrkarsdottir U, Ntzani EE, Bos SD, Esko T, Evans DS, Metrustry S, Panoutsopoulou K, Ramos YF, Thorleifsson G, Tsilidis KK, Arden N, Aslam N, Bellamy N, Birrell F, Blanco FJ, Carr A, Chapman K, Day-Williams AG, Deloukas P, Doherty M, Engström G, Helgadottir HT, Hofman A, Ingvarsson T, Jonsson H, Keis A, Keurentjes JC, Kloppenburg M, Lind PA, McCaskie A, Martin NG, Milani L, Montgomery GW, Nelissen RG, Nevitt MC, Nilsson PM, Ollier WE, Parimi N, Rai A, Ralston SH, Reed MR, Riancho JA, Rivadeneira F, Rodriguez-Fontenla C, Southam L, Thorsteinsdottir U, Tsezou A, Wallis GA, Wilkinson JM, Gonzalez A, Lane NE, Lohmander LS, Loughlin J, Metspalu A, Uitterlinden AG, Jonsdottir I, Stefansson K, Slagboom PE, Zeggini E, Meulenbelt I, Ioannidis JP, Spector TD, van Meurs JB, Valdes AM. A meta-analysis of genome-wide association studies identifies novel variants associated with osteoarthritis of the hip. Ann Rheum Dis. 2014 Dec; 73(12):2130-6. PMID: 23989986; PMCID: PMC4251181.
  334. Fanelli D, Ioannidis JP. US studies may overestimate effect sizes in softer research. Proc Natl Acad Sci U S A. 2013 Sep 10; 110(37):15031-6. PMID: 23980165; PMCID: PMC3773789.
  335. Katritsis DG, Pokushalov E, Romanov A, Giazitzoglou E, Siontis GC, Po SS, Camm AJ, Ioannidis JP. Autonomic denervation added to pulmonary vein isolation for paroxysmal atrial fibrillation: a randomized clinical trial. J Am Coll Cardiol. 2013 Dec 17; 62(24):2318-25. PMID: 23973694.
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  336. Heckman MG, Elbaz A, Soto-Ortolaza AI, Serie DJ, Aasly JO, Annesi G, Auburger G, Bacon JA, Boczarska-Jedynak M, Bozi M, Brighina L, Chartier-Harlin MC, Dardiotis E, Destée A, Ferrarese C, Ferraris A, Fiske B, Gispert S, Hadjigeorgiou GM, Hattori N, Ioannidis JP, Jasinska-Myga B, Jeon BS, Kim YJ, Klein C, Kruger R, Kyratzi E, Lin CH, Lohmann K, Loriot MA, Lynch T, Mellick GD, Mutez E, Opala G, Park SS, Petrucci S, Quattrone A, Sharma M, Silburn PA, Sohn YH, Stefanis L, Tadic V, Tomiyama H, Uitti RJ, Valente EM, Vassilatis DK, Vilariño-Güell C, White LR, Wirdefeldt K, Wszolek ZK, Wu RM, Xiromerisiou G, Maraganore DM, Farrer MJ, Ross OA. Protective effect of LRRK2 p.R1398H on risk of Parkinson's disease is independent of MAPT and SNCA variants. Neurobiol Aging. 2014 Jan; 35(1):266.e5-14. PMID: 23962496; PMCID: PMC3829604.
  337. Hernandez AV, Kaw R, Pasupuleti V, Bina P, Ioannidis JP, Bueno H, Boersma E, Gillinov M. Association between obesity and postoperative atrial fibrillation in patients undergoing cardiac operations: a systematic review and meta-analysis. Ann Thorac Surg. 2013 Sep; 96(3):1104-16. PMID: 23932258.
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  338. Heckman MG, Soto-Ortolaza AI, Aasly JO, Abahuni N, Annesi G, Bacon JA, Bardien S, Bozi M, Brice A, Brighina L, Carr J, Chartier-Harlin MC, Dardiotis E, Dickson DW, Diehl NN, Elbaz A, Ferrarese C, Fiske B, Gibson JM, Gibson R, Hadjigeorgiou GM, Hattori N, Ioannidis JP, Boczarska-Jedynak M, Jasinska-Myga B, Jeon BS, Kim YJ, Klein C, Kruger R, Kyratzi E, Lesage S, Lin CH, Lynch T, Maraganore DM, Mellick GD, Mutez E, Nilsson C, Opala G, Park SS, Petrucci S, Puschmann A, Quattrone A, Sharma M, Silburn PA, Sohn YH, Stefanis L, Tadic V, Theuns J, Tomiyama H, Uitti RJ, Valente EM, Van Broeckhoven C, van de Loo S, Vassilatis DK, Vilariño-Güell C, White LR, Wirdefeldt K, Wszolek ZK, Wu RM, Hentati F, Farrer MJ, Ross OA. Population-specific frequencies for LRRK2 susceptibility variants in the Genetic Epidemiology of Parkinson's Disease (GEO-PD) Consortium. Mov Disord. 2013 Oct; 28(12):1740-4. PMID: 23913756; PMCID: PMC4108155.
  339. Ioannidis JP. To replicate or not to replicate: the case of pharmacogenetic studies: Have pharmacogenomics failed, or do they just need larger-scale evidence and more replication? Circ Cardiovasc Genet. 2013 Aug; 6(4):413-8; discussion 418. PMID: 23963161.
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  340. David SP, Ware JJ, Chu IM, Loftus PD, Fusar-Poli P, Radua J, Munafò MR, Ioannidis JP. Potential reporting bias in fMRI studies of the brain. PLoS One. 2013; 8(7):e70104. PMID: 23936149; PMCID: PMC3723634.
  341. Ioannidis JP, Prasad V. Evaluating health system processes with randomized controlled trials. JAMA Intern Med. 2013 Jul 22; 173(14):1279-80. PMID: 23689271.
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  342. Siontis KC, Hernandez-Boussard T, Ioannidis JP. Overlapping meta-analyses on the same topic: survey of published studies. BMJ. 2013 Jul 19; 347:f4501. PMID: 23873947; PMCID: PMC3716360.
  343. Ioannidis JP. How many contemporary medical practices are worse than doing nothing or doing less? Mayo Clin Proc. 2013 Aug; 88(8):779-81. PMID: 23871231.
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  344. Tsilidis KK, Panagiotou OA, Sena ES, Aretouli E, Evangelou E, Howells DW, Al-Shahi Salman R, Macleod MR, Ioannidis JP. Evaluation of excess significance bias in animal studies of neurological diseases. PLoS Biol. 2013 Jul; 11(7):e1001609. PMID: 23874156; PMCID: PMC3712913.
  345. Saquib N, Saquib J, Ioannidis JP. Practices and impact of primary outcome adjustment in randomized controlled trials: meta-epidemiologic study. BMJ. 2013 Jul 12; 347:f4313. PMID: 23851720; PMCID: PMC3709831.
  346. Button KS, Ioannidis JP, Mokrysz C, Nosek BA, Flint J, Robinson ES, Munafò MR. Confidence and precision increase with high statistical power. Nat Rev Neurosci. 2013 Aug; 14(8):585-6. PMID: 23820778.
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  347. Crump C, Ioannidis JP, Sundquist K, Winkleby MA, Sundquist J. Mortality in persons with mental disorders is substantially overestimated using inpatient psychiatric diagnoses. J Psychiatr Res. 2013 Oct; 47(10):1298-303. PMID: 23806577; PMCID: PMC3746500.
  348. Ioannidis JP, Chang CQ, Lam TK, Schully SD, Khoury MJ. The geometric increase in meta-analyses from China in the genomic era. PLoS One. 2013; 8(6):e65602. PMID: 23776510; PMCID: PMC3680482.
  349. Ioannidis JP. Meta-analyses of hydroxyethyl starch for volume resuscitation. JAMA. 2013 Jun 05; 309(21):2209. PMID: 23736722.
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  350. Panagiotou OA, Willer CJ, Hirschhorn JN, Ioannidis JP. The power of meta-analysis in genome-wide association studies. Annu Rev Genomics Hum Genet. 2013; 14:441-65. PMID: 23724904; PMCID: PMC4040957.
  351. Mills EJ, Thorlund K, Ioannidis JP. Demystifying trial networks and network meta-analysis. BMJ. 2013 May 14; 346:f2914. PMID: 23674332.
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  352. Evangelou E, Ioannidis JP. Meta-analysis methods for genome-wide association studies and beyond. Nat Rev Genet. 2013 Jun; 14(6):379-89. PMID: 23657481.
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  353. Ioannidis JP, Hozo I, Djulbegovic B. Optimal type I and type II error pairs when the available sample size is fixed. J Clin Epidemiol. 2013 Aug; 66(8):903-910.e2. PMID: 23664493.
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  354. Porta M, Vandenbroucke JP, Ioannidis JP, Sanz S, Fernandez E, Bhopal R, Morabia A, Victora C, Lopez T. Trends in citations to books on epidemiological and statistical methods in the biomedical literature. PLoS One. 2013; 8(5):e61837. PMID: 23667447; PMCID: PMC3646840.
  355. Sigounas DE, Christodoulou DK, Tatsioni A, Katsanos KH, Baltayiannis G, Kappas A, Ioannidis JP, Tsianos EV. Pancreatitis potentially associated drugs as a risk factor for post-endoscopic retrograde cholangiopancreatography pancreatitis: a prospective cohort study. Pancreas. 2013 May; 42(4):601-6. PMID: 23548878.
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  356. Ioannidis JP. Mega-randomized clinical trials for blockbuster drugs--reply. JAMA. 2013 Apr 24; 309(16):1683. PMID: 23613069.
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  357. Tzoulaki I, Siontis KC, Evangelou E, Ioannidis JP. Bias in associations of emerging biomarkers with cardiovascular disease. JAMA Intern Med. 2013 Apr 22; 173(8):664-71. PMID: 23529078.
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  358. Ioannidis JP, Khoury MJ. Are randomized trials obsolete or more important than ever in the genomic era? Genome Med. 2013; 5(4):32. PMID: 23673134; PMCID: PMC3707036.
  359. Ioannidis JP. Expressing death risk as condensed life experience and death intensity. Med Decis Making. 2013 Aug; 33(6):853-9. PMID: 23579043.
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  360. Button KS, Ioannidis JP, Mokrysz C, Nosek BA, Flint J, Robinson ES, Munafò MR. Power failure: why small sample size undermines the reliability of neuroscience. Nat Rev Neurosci. 2013 05; 14(5):365-76. PMID: 23571845.
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  361. Ioannidis JP. Are mortality differences detected by administrative data reliable and actionable? JAMA. 2013 Apr 03; 309(13):1410-1. PMID: 23549588.
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  362. Morris AH, Ioannidis JPA. Limitations of medical research and evidence at the patient-clinician encounter scale. Chest. 2013 Apr; 143(4):1127-1135. PMID: 23546485; PMCID: PMC3616682.
  363. Stamatakis E, Weiler R, Ioannidis JP. Undue industry influences that distort healthcare research, strategy, expenditure and practice: a review. Eur J Clin Invest. 2013 May; 43(5):469-75. PMID: 23521369.
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  364. Patel CJ, Chen R, Kodama K, Ioannidis JP, Butte AJ. Systematic identification of interaction effects between validated genome- and environment-wide associations on Type 2 Diabetes Mellitus. AMIA Jt Summits Transl Sci Proc. 2013; 2013:135. PMID: 24303322.
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  365. Evangelou E, Valdes AM, Castano-Betancourt MC, Doherty M, Doherty S, Esko T, Ingvarsson T, Ioannidis JP, Kloppenburg M, Metspalu A, Ntzani EE, Panoutsopoulou K, Slagboom PE, Southam L, Spector TD, Styrkarsdottir U, Stefanson K, Uitterlinden AG, Wheeler M, Zeggini E, Meulenbelt I, van Meurs JB. The DOT1L rs12982744 polymorphism is associated with osteoarthritis of the hip with genome-wide statistical significance in males. Ann Rheum Dis. 2013 Jul; 72(7):1264-5. PMID: 23505243; PMCID: PMC3686326.
  366. Ioannidis JP. This I believe in genetics: discovery can be a nuisance, replication is science, implementation matters. Front Genet. 2013; 4:33. PMID: 23505393; PMCID: PMC3596761.
  367. McDonald KM, Matesic B, Contopoulos-Ioannidis DG, Lonhart J, Schmidt E, Pineda N, Ioannidis JP. Patient safety strategies targeted at diagnostic errors: a systematic review. Ann Intern Med. 2013 Mar 05; 158(5 Pt 2):381-9. PMID: 23460094.
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  368. Khoury MJ, Lam TK, Ioannidis JP, Hartge P, Spitz MR, Buring JE, Chanock SJ, Croyle RT, Goddard KA, Ginsburg GS, Herceg Z, Hiatt RA, Hoover RN, Hunter DJ, Kramer BS, Lauer MS, Meyerhardt JA, Olopade OI, Palmer JR, Sellers TA, Seminara D, Ransohoff DF, Rebbeck TR, Tourassi G, Winn DM, Zauber A, Schully SD. Transforming epidemiology for 21st century medicine and public health. Cancer Epidemiol Biomarkers Prev. 2013 Apr; 22(4):508-16. PMID: 23462917.
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  369. Fritsche LG, Chen W, Schu M, Yaspan BL, Yu Y, Thorleifsson G, Zack DJ, Arakawa S, Cipriani V, Ripke S, Igo RP, Buitendijk GH, Sim X, Weeks DE, Guymer RH, Merriam JE, Francis PJ, Hannum G, Agarwal A, Armbrecht AM, Audo I, Aung T, Barile GR, Benchaboune M, Bird AC, Bishop PN, Branham KE, Brooks M, Brucker AJ, Cade WH, Cain MS, Campochiaro PA, Chan CC, Cheng CY, Chew EY, Chin KA, Chowers I, Clayton DG, Cojocaru R, Conley YP, Cornes BK, Daly MJ, Dhillon B, Edwards AO, Evangelou E, Fagerness J, Ferreyra HA, Friedman JS, Geirsdottir A, George RJ, Gieger C, Gupta N, Hagstrom SA, Harding SP, Haritoglou C, Heckenlively JR, Holz FG, Hughes G, Ioannidis JP, Ishibashi T, Joseph P, Jun G, Kamatani Y, Katsanis N, N Keilhauer C, Khan JC, Kim IK, Kiyohara Y, Klein BE, Klein R, Kovach JL, Kozak I, Lee CJ, Lee KE, Lichtner P, Lotery AJ, Meitinger T, Mitchell P, Mohand-Saïd S, Moore AT, Morgan DJ, Morrison MA, Myers CE, Naj AC, Nakamura Y, Okada Y, Orlin A, Ortube MC, Othman MI, Pappas C, Park KH, Pauer GJ, Peachey NS, Poch O, Priya RR, Reynolds R, Richardson AJ, Ripp R, Rudolph G, Ryu E, Sahel JA, Schaumberg DA, Scholl HP, Schwartz SG, Scott WK, Shahid H, Sigurdsson H, Silvestri G, Sivakumaran TA, Smith RT, Sobrin L, Souied EH, Stambolian DE, Stefansson H, Sturgill-Short GM, Takahashi A, Tosakulwong N, Truitt BJ, Tsironi EE, Uitterlinden AG, van Duijn CM, Vijaya L, Vingerling JR, Vithana EN, Webster AR, Wichmann HE, Winkler TW, Wong TY, Wright AF, Zelenika D, Zhang M, Zhao L, Zhang K, Klein ML, Hageman GS, Lathrop GM, Stefansson K, Allikmets R, Baird PN, Gorin MB, Wang JJ, Klaver CC, Seddon JM, Pericak-Vance MA, Iyengar SK, Yates JR, Swaroop A, Weber BH, Kubo M, Deangelis MM, Léveillard T, Thorsteinsdottir U, Haines JL, Farrer LA, Heid IM, Abecasis GR. Seven new loci associated with age-related macular degeneration. Nat Genet. 2013 Apr; 45(4):433-9, 439e1-2. PMID: 23455636.
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  370. Ioannidis JP, Pereira TV, Horwitz RI. Emergence of large treatment effects from small trials--reply. JAMA. 2013 Feb 27; 309(8):768-9. PMID: 23443435.
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  371. Panagiotou OA, Contopoulos-Ioannidis DG, Ioannidis JP. Comparative effect sizes in randomised trials from less developed and more developed countries: meta-epidemiological assessment. BMJ. 2013 Feb 12; 346:f707. PMID: 23403829; PMCID: PMC3570069.
  372. Stefanaki I, Panagiotou OA, Kodela E, Gogas H, Kypreou KP, Chatzinasiou F, Nikolaou V, Plaka M, Kalfa I, Antoniou C, Ioannidis JP, Evangelou E, Stratigos AJ. Replication and predictive value of SNPs associated with melanoma and pigmentation traits in a Southern European case-control study. PLoS One. 2013; 8(2):e55712. PMID: 23393597; PMCID: PMC3564929.
  373. Haidich AB, Pilalas D, Contopoulos-Ioannidis DG, Ioannidis JP. Most meta-analyses of drug interventions have narrow scopes and many focus on specific agents. J Clin Epidemiol. 2013 Apr; 66(4):371-8. PMID: 23384590.
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  374. Prasad V, Jorgenson J, Ioannidis JP, Cifu A. Observational studies often make clinical practice recommendations: an empirical evaluation of authors' attitudes. J Clin Epidemiol. 2013 Apr; 66(4):361-366.e4. PMID: 23384591.
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  375. Broer L, Lill CM, Schuur M, Amin N, Roehr JT, Bertram L, Ioannidis JP, van Duijn CM. Distinguishing true from false positives in genomic studies: p values. Eur J Epidemiol. 2013 Feb; 28(2):131-8. PMID: 23371043.
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  376. Patel CJ, Chen R, Kodama K, Ioannidis JP, Butte AJ. Systematic identification of interaction effects between genome- and env