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Nathan, David
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David Matthew Nathan, M.D.
Title
Professor of Medicine
Institution
Massachusetts General Hospital
Department
Medicine
Address
Massachusetts General Hospital
Diabetes Unit, Bulfinch 408
55 Fruit St
Boston MA 02114
Phone
617/726-2874
Fax
617/726-6781
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research activities and funding
|
selected publications
|
Research
research activities and funding
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can
login
to make corrections and additions.
Most Recent
|
List All
U01DK098246
(LACHIN, JOHN M)
Sep 25, 2012 - Jul 31, 2023
NIH
Continuation of the Glycemia Reduction Approaches in Diabetes: A Comparative Effectiveness (GRADE) Study
Role: Co-Principal Investigator
U34DK088043
(NATHAN, DAVID M)
Sep 28, 2010 - Nov 30, 2012
NIH
Glycemic Reduction Approaches for Treating Diabetes: An Effectiveness Study
Role: Principal Investigator
U01DK057154
(NATHAN, DAVID M)
Sep 30, 1999 - Jan 31, 2021
NIH
04/16 Action for Health in Diabetes Extension Study Research Project
Role: Principal Investigator
U01DK048397
(NATHAN, DAVID M)
Aug 20, 1994 - Jan 31, 2022
NIH
11/22 Limited Competition for the Continuation of the Diabetes Prevention Program Outcomes Study (DPPOS) - Clinical Center
Role: Principal Investigator
U01DK030643
(NATHAN, DAVID M)
Mar 1, 1982 - Feb 28, 1999
NIH
DIABETES CONTROL AND COMPLICATIONS TRIAL
Role: Principal Investigator
U01AM030643
(NATHAN, DAVID M)
Mar 1, 1982 - Jun 30, 1986
NIH
DIABETES CONTROL AND COMPLICATIONS TRIAL (DCCT)
Role: Principal Investigator
M01RR001066
(SLAVIN, PETER L)
Feb 1, 1978 - May 31, 2008
NIH
General Clinical Research Center
Role: Co-Principal Investigator
M01RR000088
(GRAY, MARTHA L)
Nov 30, 2001
NIH
GENERAL CLINICAL RESEARCH CENTER
Role: Co-Principal Investigator
Bibliographic
selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can
login
to make corrections and additions.
Newest
|
Oldest
|
Most Cited
|
Most Discussed
|
Timeline
|
Field Summary
|
Plain Text
PMC Citations
indicate the number of times the publication was cited by articles in PubMed Central, and the
Altmetric
score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.)
Fields
are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication.
Translation
tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
Wing RR, Bray GA, Cassidy-Begay M, Clark JM, Coday M, Egan C, Evans M, Foreyt JP, Glasser S, Gregg EW, Hazuda HP, Hill JO,
Horton ES
, Isaac JC, Jakicic JM, Jeffery RW, Johnson KC, Kahn SE, Kritchevsky S, Lewis E, Maruthur NM, Maschak-Carey BJ,
Nathan DM
, Patricio J, Peters A, Pi-Sunyer X, Reboussin D, Ryan DH, Ruelas V, Steinburg H, Toledo K, Wadden TA, Wagenknecht LE, Wesche-Thobaben J, Wyatt H, Yanovski SZ, Zhang P. Effects of Intensive Lifestyle Intervention on All-Cause Mortality in Older Adults With Type 2 Diabetes and Overweight/Obesity: Results From the Look AHEAD Study. Diabetes Care. 2022 Mar 21.
PMID:
35312758
.
Citations:
Fields:
End
Endocrinology
Nathan DM
, Buse JB, Kahn SE, Krause-Steinrauf H,
Larkin ME
, Staten M,
Wexler D
, Lachin JM. Erratum. Rationale and Design of the Glycemia Reduction Approaches in Diabetes: A Comparative Effectiveness Study (GRADE). Diabetes Care 2013;36:2254-2261. Diabetes Care. 2022 Mar 01; 45(3):759.
PMID:
35020815
.
Citations:
Fields:
End
Endocrinology
Jakicic JM, Berkowitz RI, Bolin P, Bray GA, Clark JM, Coday M, Egan C, Evans M, Foreyt JP, Fulton JE, Greenway FL, Gregg EW, Hazuda HP, Hill JO,
Horton ES
, Hubbard VS, Jeffery RW, Johnson KC, Johnson R, Kahn SE, Kure A, Lang W, Lewis CE,
Nathan DM
, Patricio J, Peters A, Pi-Sunyer X, Pownall H, Rejeski WJ, Safford M, Stewart KJ, Wadden TA, Walkup MP, Wing RR, Wyatt H. Association Between Change in Accelerometer-Measured and Self-Reported Physical Activity and Cardiovascular Disease in the Look AHEAD Trial. Diabetes Care. 2022 03 01; 45(3):742-749.
PMID:
35019976
.
Citations:
Fields:
End
Endocrinology
Translation:
Humans
O'Connell J,
Nathan DM
, O'Brien T, O'Keeffe DT. Treatment of Diabetes - To Pump or Not to Pump. N Engl J Med. 2021 Nov 25; 385(22):2092-2095.
PMID:
34818486
.
Citations:
Fields:
Med
Medicine (General)
Translation:
Humans
Nathan DM
, Krause-Steinrauf H, Braffett BH, Arends VL, Younes N, McGee P, Lund C, Johnson M, Lorenzi G, Gao X, Steffes MW, Lachin JM. Comparison of central laboratory HbA1c measurements obtained from a capillary collection versus a standard venous whole blood collection in the GRADE and EDIC studies. PLoS One. 2021; 16(11):e0257154.
PMID:
34780485
.
Citations:
Fields:
Med
Medicine (General)
Sci
Science
Translation:
Humans
Lachin JM,
Nathan DM
. Understanding Metabolic Memory: The Prolonged Influence of Glycemia During the Diabetes Control and Complications Trial (DCCT) on Future Risks of Complications During the Study of the Epidemiology of Diabetes Interventions and Complications (EDIC). Diabetes Care. 2021 Sep 21.
PMID:
34548284
.
Citations:
1
Fields:
End
Endocrinology
Lachin JM, Bebu I,
Nathan DM
. The Beneficial Effects of Earlier Versus Later Implementation of Intensive Therapy in Type 1 Diabetes. Diabetes Care. 2021 Aug 11.
PMID:
34380706
.
Citations:
2
Fields:
End
Endocrinology
Bjornstad P, Drews KL, Caprio S, Gubitosi-Klug R,
Nathan DM
, Tesfaldet B, Tryggestad J, White NH, Zeitler P. Long-Term Complications in Youth-Onset Type 2 Diabetes. N Engl J Med. 2021 07 29; 385(5):416-426.
PMID:
34320286
.
Citations:
8
Fields:
Med
Medicine (General)
Translation:
Humans
Bebu I, Keshavarzi S, Gao X, Braffett BH, Canty AJ, Herman WH, Orchard TJ, Dagogo-Jack S,
Nathan DM
, Lachin JM, Paterson AD. Genetic Risk Factors for CVD in Type 1 Diabetes: The DCCT/EDIC Study. Diabetes Care. 2021 06; 44(6):1309-1316.
PMID:
33883194
.
Citations:
1
Fields:
End
Endocrinology
Translation:
Humans
Izzy S
, Tahir Z,
Grashow R
, Cote DJ, Jarrah AA,
Dhand A
, Taylor H,
Whalen M
,
Nathan DM
,
Miller KK
,
Speizer F
,
Baggish A
,
Weisskopf MG
,
Zafonte R
. Concussion and Risk of Chronic Medical and Behavioral Health Comorbidities. J Neurotrauma. 2021 06 01; 38(13):1834-1841.
PMID:
33451255
.
Citations:
Fields:
Neu
Neurology
Tra
Traumatology
Translation:
Humans
Nathan DM
. Realising the long-term promise of insulin therapy: the DCCT/EDIC study. Diabetologia. 2021 05; 64(5):1049-1058.
PMID:
33550441
.
Citations:
5
Fields:
End
Endocrinology
Translation:
Humans
Bebu I, Braffett BH, Orchard TJ, Lorenzi GM,
Nathan DM
, Herman WH, Lachin JM. Moderation of the effect of glycemia on the risk of cardiovascular disease in type 1 diabetes: The DCCT/EDIC study. Diabetes Res Clin Pract. 2021 Jan; 171:108591.
PMID:
33310124
.
Citations:
2
Fields:
End
Endocrinology
Translation:
Humans
Zhang P, Atkinson KM, Bray GA, Chen H, Clark JM, Coday M, Dutton GR, Egan C, Espeland MA, Evans M, Foreyt JP, Greenway FL, Gregg EW, Hazuda HP, Hill JO,
Horton ES
, Hubbard VS, Huckfeldt PJ, Jackson SD, Jakicic JM, Jeffery RW, Johnson KC, Kahn SE, Killean T, Knowler WC, Korytkowski M, Lewis CE, Maruthur NM, Michaels S, Montez MG,
Nathan DM
, Patricio J, Peters A, Pi-Sunyer X, Pownall H, Redmon B, Rushing JT, Steinburg H, Wadden TA, Wing RR, Wyatt H, Yanovski SZ. Within-Trial Cost-Effectiveness of a Structured Lifestyle Intervention in Adults With Overweight/Obesity and Type 2 Diabetes: Results From the Action for Health in Diabetes (Look AHEAD) Study. Diabetes Care. 2021 01; 44(1):67-74.
PMID:
33168654
.
Citations:
1
Fields:
End
Endocrinology
Translation:
Humans
Munshi MN
, Meneilly GS, Rodríguez-Mañas L, Close KL,
Conlin PR
, Cukierman-Yaffe T, Forbes A,
Ganda OP
,
Kahn CR
, Huang E, Laffel LM, Lee CG, Lee S,
Nathan DM
, Pandya N, Pratley R,
Gabbay R
, Sinclair AJ. Diabetes in ageing: pathways for developing the evidence base for clinical guidance. Lancet Diabetes Endocrinol. 2020 10; 8(10):855-867.
PMID:
32946822
.
Citations:
3
Fields:
End
Endocrinology
Translation:
Humans
Yeh HC, Bantle JP, Cassidy-Begay M, Blackburn G, Bray GA, Byers T, Clark JM, Coday M, Egan C, Espeland MA, Foreyt JP, Garcia K, Goldman V, Gregg EW, Hazuda HP, Hesson L, Hill JO,
Horton ES
, Jakicic JM, Jeffery RW, Johnson KC, Kahn SE, Knowler WC, Korytkowski M, Kure A, Lewis CE,
Mantzoros C
, Meacham M, Montez MG,
Nathan DM
, Pajewski N, Patricio J, Peters A, Xavier Pi-Sunyer F, Pownall H, Ryan DH, Safford M, Sedjo RL, Steinburg H, Vitolins M, Wadden TA, Wagenknecht LE, Wing RR, Wolff AC, Wyatt H, Yanovski SZ. Intensive Weight Loss Intervention and Cancer Risk in Adults with Type 2 Diabetes: Analysis of the Look AHEAD Randomized Clinical Trial. Obesity (Silver Spring). 2020 09; 28(9):1678-1686.
PMID:
32841523
.
Citations:
7
Fields:
Met
Metabolism
Nut
Nutritional Sciences
Phy
Physiology
Translation:
Humans
Lachin JM,
Nathan DM
, Zinman B, Bebu I. Comment on Miller and Orchard: Understanding Metabolic Memory: A Tale of Two Studies. Diabetes 2020;69:291-299. Diabetes. 2020 07; 69(7):e7-e8.
PMID:
32561623
.
Citations:
3
Fields:
End
Endocrinology
Translation:
Humans
Edelson PK,
James KE
,
Leong A
, Arenas J, Cayford M, Callahan MJ,
Bernstein SN
,
Tangren JS
,
Hivert MF
,
Higgins JM
,
Nathan DM
,
Powe CE
. Longitudinal Changes in the Relationship Between Hemoglobin A1c and Glucose Tolerance Across Pregnancy and Postpartum. J Clin Endocrinol Metab. 2020 05 01; 105(5).
PMID:
32010954
.
Citations:
6
Fields:
End
Endocrinology
Met
Metabolism
Translation:
Humans
Cells
Smetana GW
,
Nathan DM
, Dugdale DC,
Burns RB
. To What Target Hemoglobin A1c Level Would You Treat This Patient With Type 2 Diabetes?: Grand Rounds Discussion From Beth Israel Deaconess Medical Center. Ann Intern Med. 2019 10 01; 171(7):505-513.
PMID:
31569249
.
Citations:
Fields:
Int
Internal Medicine
Translation:
Humans
Larkin ME
,
Nathan DM
, Bebu I, Krause-Steinrauf H, Herman WH,
Higgins JM
, Tiktin M, Cohen RM, Lund C, Bergenstal RM, Johnson ML, Arends V. Rationale and Design for a GRADE Substudy of Continuous Glucose Monitoring. Diabetes Technol Ther. 2019 12; 21(12):682-690.
PMID:
31393176
.
Citations:
2
Fields:
End
Endocrinology
The
Therapeutics
Translation:
Humans
CT
Clinical Trials
Nathan DM
, Bennett PH, Crandall JP, Edelstein SL, Goldberg RB, Kahn SE, Knowler WC, Mather KJ, Mudaliar S, Orchard TJ, Temprosa M, White NH. Does diabetes prevention translate into reduced long-term vascular complications of diabetes? Diabetologia. 2019 08; 62(8):1319-1328.
PMID:
31270584
.
Citations:
13
Fields:
End
Endocrinology
Translation:
Humans
Nathan DM
, Griffin A, Perez FM, Basque E, Do L, Steiner B. Accuracy of a Point-of-Care Hemoglobin A1c Assay. J Diabetes Sci Technol. 2019 11; 13(6):1149-1153.
PMID:
30943787
.
Citations:
2
Fields:
End
Endocrinology
Translation:
Humans
Houston DK, Neiberg RH, Miller ME, Hill JO, Jakicic JM, Johnson KC, Gregg EW, Hubbard VS, Pi-Sunyer X, Rejeski WJ, Wing RR, Bantle JP, Beale E, Berkowitz RI, Cassidy-Begay M, Clark JM, Coday M,
Delahanty LM
, Dutton G, Egan C, Foreyt JP, Greenway FL, Hazuda HP, Hergenroeder A,
Horton ES
, Jeffery RW, Kahn SE, Kure A, Knowler WC, Lewis CE, Martin CK, Michaels S, Montez MG,
Nathan DM
, Patricio J, Peters A, Pownall H, Regensteiner J, Steinburg H, Wadden TA, White K, Yanovski SZ, Zhang P, Kritchevsky SB. Physical Function Following a Long-Term Lifestyle Intervention Among Middle Aged and Older Adults With Type 2 Diabetes: The Look AHEAD Study. J Gerontol A Biol Sci Med Sci. 2018 10 08; 73(11):1552-1559.
PMID:
29053861
.
Citations:
14
Fields:
Ger
Geriatrics
Translation:
Humans
Nathan DM
. Diagnosing diabetes mellitus - best practices still unclear. Nat Rev Endocrinol. 2018 10; 14(10):572-573.
PMID:
30054564
.
Citations:
Fields:
End
Endocrinology
Translation:
Humans
Draznin B,
Nathan DM
, Korytkowski MT,
McDonnell ME
, Golden SH, Schutta MH, Cefalu WT. Guidelines Versus Guidelines: What's Best for the Patient? Ann Intern Med. 2018 08 07; 169(3):186-187.
PMID:
29800101
.
Citations:
Fields:
Int
Internal Medicine
Translation:
Humans
Fan W
, Zheng H,
Wei N
,
Nathan DM
. Estimating HbA1c from timed Self-Monitored Blood Glucose values. Diabetes Res Clin Pract. 2018 Jul; 141:56-61.
PMID:
29673846
.
Citations:
3
Fields:
End
Endocrinology
Translation:
Humans
Arnold SE
, Arvanitakis Z, Macauley-Rambach SL, Koenig AM, Wang HY, Ahima RS, Craft S, Gandy S, Buettner C, Stoeckel LE, Holtzman DM,
Nathan DM
. Brain insulin resistance in type 2 diabetes and Alzheimer disease: concepts and conundrums. Nat Rev Neurol. 2018 03; 14(3):168-181.
PMID:
29377010
.
Citations:
253
Fields:
Neu
Neurology
Translation:
Humans
Lachin JM, Bebu I, Bergenstal RM, Pop-Busui R, Service FJ, Zinman B,
Nathan DM
. Response to Comment on Lachin et al. Association of Glycemic Variability in Type 1 Diabetes With Progression of Microvascular Outcomes in the Diabetes Control and Complications Trial. Diabetes Care 2017;40:777-783. Diabetes Care. 2017 11; 40(11):e165-e166.
PMID:
29061594
.
Citations:
Fields:
End
Endocrinology
Translation:
Humans
Nathan DM
. Adjunctive Treatments for Type 1 Diabetes. N Engl J Med. 2017 12 14; 377(24):2390-2391.
PMID:
28899219
.
Citations:
3
Fields:
Med
Medicine (General)
Translation:
Humans
Majithia AR, Wiltschko AB, Zheng H, Walford GA,
Nathan DM
. Rate of Change of Premeal Glucose Measured by Continuous Glucose Monitoring Predicts Postmeal Glycemic Excursions in Patients With Type 1 Diabetes: Implications for Therapy. J Diabetes Sci Technol. 2018 01; 12(1):76-82.
PMID:
28868899
.
Citations:
1
Fields:
End
Endocrinology
Translation:
Humans
Aroda VR
, Knowler WC, Crandall JP, Perreault L, Edelstein SL, Jeffries SL, Molitch ME, Pi-Sunyer X, Darwin C, Heckman-Stoddard BM, Temprosa M, Kahn SE,
Nathan DM
. Metformin for diabetes prevention: insights gained from the Diabetes Prevention Program/Diabetes Prevention Program Outcomes Study. Diabetologia. 2017 09; 60(9):1601-1611.
PMID:
28770322
.
Citations:
36
Fields:
End
Endocrinology
Translation:
Humans
Johnson KC, Bray GA, Cheskin LJ, Clark JM, Egan CM, Foreyt JP, Garcia KR, Glasser S, Greenway FL, Gregg EW, Hazuda HP, Hergenroeder A, Hill JO,
Horton ES
, Jakicic JM, Jeffery RW, Kahn SE, Knowler WC, Lewis CE, Miller M, Montez MG,
Nathan DM
, Patricio JL, Peters AL, Pi-Sunyer X, Pownall HJ, Reboussin D, Redmon JB, Steinberg H, Wadden TA, Wagenknecht LE, Wing RR, Womack CR, Yanovski SZ, Zhang P, Schwartz AV. The Effect of Intentional Weight Loss on Fracture Risk in Persons With Diabetes: Results From the Look AHEAD Randomized Clinical Trial. J Bone Miner Res. 2017 Nov; 32(11):2278-2287.
PMID:
28678345
.
Citations:
26
Fields:
Met
Metabolism
Ort
Orthopedics
Translation:
Humans
Bebu I, Braffett BH, Pop-Busui R, Orchard TJ,
Nathan DM
, Lachin JM. The relationship of blood glucose with cardiovascular disease is mediated over time by traditional risk factors in type 1 diabetes: the DCCT/EDIC study. Diabetologia. 2017 10; 60(10):2084-2091.
PMID:
28711972
.
Citations:
29