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Guo-Ping Shi, Sc.D., D.Sc.

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Biography
Harvard School of Public Health, BostonScD06/1995Environmental Health (Respiratory Biology)

Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01HL151627 (SHI, GUO-PING) Jan 1, 2021 - Dec 31, 2024
    NIH
    Role of ILC2 and eosinophils in abdominal aortic aneurysm
    Role: Principal Investigator
  2. R01AG063839 (SHI, GUO-PING) Apr 15, 2020 - Feb 28, 2025
    NIH
    Role of Mast cells in Alzheimer's Disease
    Role: Principal Investigator
  3. R56AG058670 (SHI, GUO-PING) Sep 30, 2018 - Aug 31, 2020
    NIH
    Role of mast cells in Alzheimer's Disease
    Role: Principal Investigator
  4. R01HL123568 (SHI, GUO-PING) Aug 21, 2015 - May 31, 2020
    NIH
    Role of a novel IL18 binding protein in atherosclerosis
    Role: Principal Investigator
  5. R01HL060942 (SHI, GUO-PING) May 1, 2009 - Dec 31, 1999
    NIH
    Leptin deficiency changes mast cell pro-inflammatory activity
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Song J, Gong YH, Yan X, Liu Y, Zhang M, Luo J, Jiang CM, Zhang M, Shi GP, Zhu W. Regulatory T Cells Accelerate the Repair Process of Renal Fibrosis by Regulating Mononuclear Macrophages. Am J Med Sci. 2021 Mar 02. PMID: 33667434.
    Citations:    Fields:    
  2. Cai Y, Liang R, Xiao S, Huang Q, Zhu D, Shi GP, Ouyang Q, Yang M. Circ_0088194 Promotes the Invasion and Migration of Rheumatoid Arthritis Fibroblast-Like Synoviocytes via the miR-766-3p/MMP2 Axis. Front Immunol. 2021; 12:628654. PMID: 33692802.
    Citations:    Fields:    
  3. Liu J, Yang C, Liu T, Deng Z, Fang W, Zhang X, Li J, Huang Q, Liu C, Wang Y, Yang D, Sukhova GK, Lindholt JS, Diederichsen A, Rasmussen LM, Li D, Newton G, Luscinskas FW, Liu L, Libby P, Wang J, Guo J, Shi GP. Eosinophils improve cardiac function after myocardial infarction. Nat Commun. 2020 12 16; 11(1):6396. PMID: 33328477.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  4. Liu CL, Liu X, Zhang Y, Liu J, Yang C, Luo S, Liu T, Wang Y, Lindholt JS, Diederichsen A, Rasmussen LM, Dahl M, Sukhova GK, Lu G, Upchurch GR, Libby P, Guo J, Zhang J, Shi GP. Eosinophils Protect Mice From Angiotensin-II Perfusion-Induced Abdominal Aortic Aneurysm. Circ Res. 2021 Jan 22; 128(2):188-202. PMID: 33153394.
    Citations:    Fields:    
  5. Yang C, Liu T, Shi GP. Therapeutic potential of tricarboxylic acid cycle metabolite itaconate in cardiovascular diseases. EBioMedicine. 2020 Sep; 59:102938. PMID: 32810823.
    Citations:    Fields:    
  6. Meng X, Piao L, Wang H, Inoue A, Huang Z, Jiang H, Nakamura K, Sasaki T, Li X, Xu W, Yu C, Hu L, Wu H, Murohara T, Shi GP, Kuzuya M, Cheng XW. Deficiency of cysteinyl cathepsin K suppresses the development of experimental intimal hyperplasia in response to chronic stress. J Hypertens. 2020 08; 38(8):1514-1524. PMID: 32205563.
    Citations: 1     Fields:    
  7. Liu CL, Ren J, Wang Y, Zhang X, Sukhova GK, Liao M, Santos M, Luo S, Yang D, Xia M, Inouye K, Hotamisligil GS, Lu G, Upchurch GR, Libby P, Guo J, Zhang J, Shi GP. Adipocytes promote interleukin-18 binding to its receptors during abdominal aortic aneurysm formation in mice. Eur Heart J. 2020 07 07; 41(26):2456-2468. PMID: 31821481.
    Citations: 6     Fields:    
  8. Fang W, Deng Z, Benadjaoud F, Yang D, Yang C, Shi GP. Regulatory T cells promote adipocyte beiging in subcutaneous adipose tissue. FASEB J. 2020 07; 34(7):9755-9770. PMID: 32510702.
    Citations: 4     Fields:    Translation:AnimalsCells
  9. Liu CL, Liu X, Wang Y, Deng Z, Liu T, Sukhova GK, Wojtkiewicz GR, Tang R, Zhang JY, Achilefu S, Nahrendorf M, Libby P, Wang X, Shi GP. Reduced Nhe1 (Na+-H+ Exchanger-1) Function Protects ApoE-Deficient Mice From Ang II (Angiotensin II)-Induced Abdominal Aortic Aneurysms. Hypertension. 2020 07; 76(1):87-100. PMID: 32475310.
    Citations:    Fields:    Translation:HumansAnimalsCells
  10. Liu T, Luo S, Libby P, Shi GP. Cathepsin L-selective inhibitors: A potentially promising treatment for COVID-19 patients. Pharmacol Ther. 2020 09; 213:107587. PMID: 32470470.
    Citations: 42     Fields:    Translation:HumansCellsPHPublic Health
  11. Fang W, Deng Z, Benadjaoud F, Yang C, Shi GP. Cathepsin B deficiency ameliorates liver lipid deposition, inflammatory cell infiltration, and fibrosis after diet-induced nonalcoholic steatohepatitis. Transl Res. 2020 08; 222:28-40. PMID: 32434697.
    Citations: 1     Fields:    Translation:AnimalsCells
  12. Zhang X, Li J, Luo S, Wang M, Huang Q, Deng Z, de Febbo C, Daoui A, Liew PX, Sukhova GK, Metso J, Jauhiainen M, Shi GP, Guo J. IgE Contributes to Atherosclerosis and Obesity by Affecting Macrophage Polarization, Macrophage Protein Network, and Foam Cell Formation. Arterioscler Thromb Vasc Biol. 2020 03; 40(3):597-610. PMID: 31996021.
    Citations: 4     Fields:    Translation:AnimalsCells
  13. Zhang X, Luo S, Wang M, Shi GP. Cysteinyl cathepsins in cardiovascular diseases. Biochim Biophys Acta Proteins Proteom. 2020 04; 1868(4):140360. PMID: 31926332.
    Citations: 3     Fields:    Translation:HumansAnimals
  14. Li J, Deng Z, Zhang X, Liu F, Yang C, Shi GP. Deficiency of immunoglobulin E protects mice from experimental abdominal aortic aneurysms. FASEB J. 2020 02; 34(2):3091-3104. PMID: 31909541.
    Citations:    Fields:    Translation:AnimalsCells
  15. Hu L, Huang Z, Ishii H, Wu H, Suzuki S, Inoue A, Kim W, Jiang H, Li X, Zhu E, Piao L, Zhao G, Lei Y, Okumura K, Shi GP, Murohara T, Kuzuya M, Cheng XW. PLF-1 (Proliferin-1) Modulates Smooth Muscle Cell Proliferation and Development of Experimental Intimal Hyperplasia. J Am Heart Assoc. 2019 12 17; 8(24):e005886. PMID: 31838975.
    Citations: 3     Fields:    Translation:AnimalsCells
  16. Zhang N, Shi GP, Wang Y, Chu XF, Wang ZD, Shi JM, Guo JH, Wang YC, Yao S, Jiang XY, Zhu YS, Wang XF. Depressive symptoms are associated with incident frailty in a Chinese population: the Rugao Longevity and Aging Study. Aging Clin Exp Res. 2020 Nov; 32(11):2297-2302. PMID: 31786744.
    Citations:    Fields:    Translation:Humans
  17. Liu CL, Shi GP. Calcium-activated chloride channel regulator 1 (CLCA1): More than a regulator of chloride transport and mucus production. World Allergy Organ J. 2019 Nov; 12(11):100077. PMID: 31871532.
    Citations: 3     
  18. Lin Y, Bao B, Yin H, Wang X, Feng A, Zhao L, Nie X, Yang N, Shi GP, Liu J. Peripheral cathepsin L inhibition induces fat loss in C. elegans and mice through promoting central serotonin synthesis. BMC Biol. 2019 11 26; 17(1):93. PMID: 31771567.
    Citations:    Fields:    Translation:Animals
  19. Xu W, Yu C, Piao L, Inoue A, Wang H, Meng X, Li X, Cui L, Umegaki H, Shi GP, Murohara T, Kuzuya M, Cheng XW. Cathepsin S-Mediated Negative Regulation of Wnt5a/SC35 Activation Contributes to Ischemia-Induced Neovascularization in Aged Mice. Circ J. 2019 11 25; 83(12):2537-2546. PMID: 31645525.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  20. Liu CL, Zhang X, Liu J, Wang Y, Sukhova GK, Wojtkiewicz GR, Liu T, Tang R, Achilefu S, Nahrendorf M, Libby P, Guo J, Zhang JY, Shi GP. Na+-H+ exchanger 1 determines atherosclerotic lesion acidification and promotes atherogenesis. Nat Commun. 2019 09 04; 10(1):3978. PMID: 31484936.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  21. Song J, Xia Y, Yan X, Luo J, Jiang C, Zhang M, Shi GP, Zhu W. Losartan accelerates the repair process of renal fibrosis in UUO mouse after the surgical recanalization by upregulating the expression of Tregs. Int Urol Nephrol. 2019 Nov; 51(11):2073-2081. PMID: 31401712.
    Citations:    Fields:    Translation:AnimalsCells
  22. Zhang X, Zhou Y, Yu X, Huang Q, Fang W, Li J, Bonventre JV, Sukhova GK, Libby P, Shi GP. Differential Roles of Cysteinyl Cathepsins in TGF-ß Signaling and Tissue Fibrosis. iScience. 2019 Sep 27; 19:607-622. PMID: 31446224.
    Citations: 9     
  23. Gu H, Xiong P, Tang H, Chen S, Long Y, Shi G. In vivo monitoring of cerebral glucose with an updated on-line electroanalytical system. Anal Bioanal Chem. 2019 Sep; 411(23):5929-5935. PMID: 31338538.
    Citations:    Fields:    Translation:Animals
  24. Zhang X, Wang X, Yin H, Zhang L, Feng A, Zhang QX, Lin Y, Bao B, Hernandez LL, Shi GP, Liu J. Functional Inactivation of Mast Cells Enhances Subcutaneous Adipose Tissue Browning in Mice. Cell Rep. 2019 07 16; 28(3):792-803.e4. PMID: 31315055.
    Citations: 13     Fields:    Translation:AnimalsCells
  25. Wang H, Meng X, Piao L, Inoue A, Xu W, Yu C, Nakamura K, Hu L, Sasaki T, Wu H, Unno K, Umegaki H, Murohara T, Shi GP, Kuzuya M, Cheng XW. Cathepsin S Deficiency Mitigated Chronic Stress-Related Neointimal Hyperplasia in Mice. J Am Heart Assoc. 2019 07 16; 8(14):e011994. PMID: 31296090.
    Citations: 9     Fields:    Translation:AnimalsCells
  26. Zhao R, He XW, Shi YH, Liu YS, Liu FD, Hu Y, Zhuang MT, Feng XY, Zhao L, Zhao BQ, Liu HQ, Shi GP, Liu JR. Cathepsin K Knockout Exacerbates Haemorrhagic Transformation Induced by Recombinant Tissue Plasminogen Activator After Focal Cerebral Ischaemia in Mice. Cell Mol Neurobiol. 2019 Aug; 39(6):823-831. PMID: 31065924.
    Citations: 2     Fields:    Translation:AnimalsCells
  27. Zhang X, Huang Q, Wang X, Deng Z, Li J, Yan X, Jauhiainen M, Metso J, Libby P, Liu J, Shi GP. Dietary cholesterol is essential to mast cell activation and associated obesity and diabetes in mice. Biochim Biophys Acta Mol Basis Dis. 2019 06 01; 1865(6):1690-1700. PMID: 30978390.
    Citations: 2     Fields:    Translation:AnimalsCells
  28. Li J, Xia N, Wen S, Li D, Lu Y, Gu M, Tang T, Jiao J, Lv B, Nie S, Liao M, Liao Y, Yang X, Hu Y, Shi GP, Cheng X. IL (Interleukin)-33 Suppresses Abdominal Aortic Aneurysm by Enhancing Regulatory T-Cell Expansion and Activity. Arterioscler Thromb Vasc Biol. 2019 03; 39(3):446-458. PMID: 30651000.
    Citations: 7     Fields:    Translation:AnimalsCells
  29. Chen ZH, Han XY, Lin ZY, Fan YL, Shi G, Zhang S, Zhang M. Facile reflux synthesis of polyethyleneimine-capped fluorescent carbon dots for sequential bioassays toward Cu2+ /H2 S and its application for a logic system. Biotechnol Appl Biochem. 2019 May; 66(3):426-433. PMID: 30806989.
    Citations: 2     Fields:    
  30. Pu C, Xu Y, Liu Q, Zhu A, Shi G. Enantiomers of Single Chirality Nanotube as Chiral Recognition Interface for Enhanced Electrochemical Chiral Analysis. Anal Chem. 2019 02 19; 91(4):3015-3020. PMID: 30644729.
    Citations:    Fields:    
  31. He A, Fang W, Zhao K, Wang Y, Li J, Yang C, Benadjaoud F, Shi GP. Mast cell-deficiency protects mice from streptozotocin-induced diabetic cardiomyopathy. Transl Res. 2019 06; 208:1-14. PMID: 30738862.
    Citations: 3     Fields:    Translation:AnimalsCells
  32. Wang Y, Liu CL, Fang W, Zhang X, Yang C, Li J, Liu J, Sukhova GK, Gurish MF, Libby P, Shi GP, Zhang J. Deficiency of mouse mast cell protease 4 mitigates cardiac dysfunctions in mice after myocardium infarction. Biochim Biophys Acta Mol Basis Dis. 2019 06 01; 1865(6):1170-1181. PMID: 30639224.
    Citations: 3     Fields:    Translation:AnimalsCells
  33. Tang H, Cai D, Ren T, Xiong P, Liu Y, Gu H, Shi G. Fabrication of a low background signal glucose biosensor with 3D network materials as the electrocatalyst. Anal Biochem. 2019 02 15; 567:63-71. PMID: 30571945.
    Citations: 2     Fields:    Translation:Cells
  34. Fang W, He A, Xiang MX, Lin Y, Wang Y, Li J, Yang C, Zhang X, Liu CL, Sukhova GK, Barascuk N, Larsen L, Karsdal M, Libby P, Shi GP. Cathepsin K-deficiency impairs mouse cardiac function after myocardial infarction. J Mol Cell Cardiol. 2019 02; 127:44-56. PMID: 30465799.
    Citations: 4     Fields:    Translation:HumansAnimals
  35. Shi GP, Ma T, Zhu YS, Wang ZD, Chu XF, Wang Y, Chen ZK, Xu WD, Wang XF, Guo JH, Jiang XY. Frailty phenotype, frailty index and risk of mortality in Chinese elderly population- Rugao longevity and ageing study. Arch Gerontol Geriatr. 2019 Jan - Feb; 80:115-119. PMID: 30448694.
    Citations: 3     Fields:    Translation:Humans
  36. Wang J, Cheng X, Xiang MX, Alanne-Kinnunen M, Wang JA, Chen H, He A, Sun X, Lin Y, Tang TT, Tu X, Sjöberg S, Sukhova GK, Liao YH, Conrad DH, Yu L, Kawakami T, Kovanen PT, Libby P, Shi GP. IgE stimulates human and mouse arterial cell apoptosis and cytokine expression and promotes atherogenesis in Apoe-/- mice. J Clin Invest. 2018 11 01; 128(11):5184. PMID: 30382945.
    Citations:    Fields:    
  37. Wang Y, Liu CL, Lindholt JS, Shi GP, Zhang J. Plasma Cystatin B Association With Abdominal Aortic Aneurysms and Need for Later Surgical Repair: A Sub-study of the VIVA Trial. Eur J Vasc Endovasc Surg. 2018 Dec; 56(6):826-832. PMID: 30262158.
    Citations: 2     Fields:    Translation:Humans
  38. Ouyang Q, Huang Q, Jiang Z, Zhao J, Shi GP, Yang M. Using plasma circRNA_002453 as a novel biomarker in the diagnosis of lupus nephritis. Mol Immunol. 2018 09; 101:531-538. PMID: 30172209.
    Citations: 22     Fields:    Translation:HumansCells
  39. Chen ZH, Han XY, Deng LX, Lin ZY, Mu FY, Zhang S, Shi G, Zhang M. A self-calibrating logic system and oxidase-based biosensor using Tb3+-doped carbon dots/DNA conjugates. Talanta. 2019 Jan 01; 191:235-240. PMID: 30262056.
    Citations:    Fields:    Translation:AnimalsCells
  40. Tang TT, Li YY, Li JJ, Wang K, Han Y, Dong WY, Zhu ZF, Xia N, Nie SF, Zhang M, Zeng ZP, Lv BJ, Jiao J, Liu H, Xian ZS, Yang XP, Hu Y, Liao YH, Wang Q, Tu X, Mallat Z, Huang Y, Shi GP, Cheng X. Liver-heart crosstalk controls IL-22 activity in cardiac protection after myocardial infarction. Theranostics. 2018; 8(16):4552-4562. PMID: 30214638.
    Citations: 13     Fields:    Translation:Animals
  41. Liu CL, Guo J, Zhang X, Sukhova GK, Libby P, Shi GP. Cysteine protease cathepsins in cardiovascular disease: from basic research to clinical trials. Nat Rev Cardiol. 2018 06; 15(6):351-370. PMID: 29679024.
    Citations: 29     Fields:    Translation:HumansAnimalsCells
  42. Ma T, Lu D, Zhu YS, Chu XF, Wang Y, Shi GP, Wang ZD, Yu L, Jiang XY, Wang XF. ACTN3 genotype and physical function and frailty in an elderly Chinese population: the Rugao Longevity and Ageing Study. Age Ageing. 2018 May 01; 47(3):416-422. PMID: 29447359.
    Citations: 7     Fields:    Translation:Humans
  43. Ma T, Cai J, Zhu YS, Chu XF, Wang Y, Shi GP, Wang ZD, Yao S, Wang XF, Jiang XY. Association between a frailty index based on common laboratory tests and QTc prolongation in older adults: the Rugao Longevity and Ageing Study. Clin Interv Aging. 2018; 13:797-804. PMID: 29731619.
    Citations: 2     Fields:    Translation:Humans
  44. Xue SF, Chen ZH, Han XY, Lin ZY, Wang QX, Zhang M, Shi G. DNA Encountering Terbium(III): A Smart "Chemical Nose/Tongue" for Large-Scale Time-Gated Luminescent and Lifetime-Based Sensing. Anal Chem. 2018 03 06; 90(5):3443-3451. PMID: 29433302.
    Citations: 2     Fields:    Translation:PHPublic Health
  45. Xue SF, Zhang JF, Chen ZH, Han XY, Zhang M, Shi G. Multifunctional fluorescent sensing of chemical and physical stimuli using smart riboflavin-5'-phosphate/Eu3+ coordination polymers. Anal Chim Acta. 2018 Jul 05; 1012:74-81. PMID: 29475476.
    Citations:    Fields:    
  46. Ogasawara S, Cheng XW, Inoue A, Hu L, Piao L, Yu C, Goto H, Xu W, Zhao G, Lei Y, Yang G, Kimura K, Umegaki H, Shi GP, Kuzuya M. Cathepsin K activity controls cardiotoxin-induced skeletal muscle repair in mice. J Cachexia Sarcopenia Muscle. 2018 02; 9(1):160-175. PMID: 29058826.
    Citations: 5     Fields:    Translation:Animals
  47. Libby P, Sukhova GK, Ozaki CK, Shi GP. Tilting at the tilted protease balance in arterial aneurysmal disease. Cardiovasc Res. 2017 09 01; 113(11):1279-1281. PMID: 28859304.
    Citations:    Fields:    Translation:HumansCells
  48. Zhu Z, Liang L, Zhang R, Wei Y, Su L, Tejera P, Guo Y, Wang Z, Lu Q, Baccarelli AA, Zhu X, Bajwa EK, Taylor Thompson B, Shi GP, Christiani DC. Whole blood microRNA markers are associated with acute respiratory distress syndrome. Intensive Care Med Exp. 2017 Aug 30; 5(1):38. PMID: 28856588.
    Citations: 12     
  49. Jin DY, Liu CL, Tang JN, Zhu ZZ, Xuan XX, Zhu XD, Wang YZ, Zhang TX, Shen DL, Wang XF, Shi GP, Zhang JY. Interleukin-18, matrix metalloproteinase-22 and -29 are independent risk factors of human coronary heart disease. J Zhejiang Univ Sci B. 2017 Aug.; 18(8):685-695. PMID: 28786243.
    Citations:    Fields:    
  50. Ouyang Q, Wu J, Jiang Z, Zhao J, Wang R, Lou A, Zhu D, Shi GP, Yang M. Microarray Expression Profile of Circular RNAs in Peripheral Blood Mononuclear Cells from Rheumatoid Arthritis Patients. Cell Physiol Biochem. 2017; 42(2):651-659. PMID: 28618429.
    Citations: 39     Fields:    Translation:HumansCells
  51. Qi YX, Qu ZB, Wang QX, Zhang M, Shi G. Nanomolar sensitive colorimetric assay for Mn2+ using cysteic acid-capped silver nanoparticles and theoretical investigation of its sensing mechanism. Anal Chim Acta. 2017 Aug 08; 980:65-71. PMID: 28622805.
    Citations:    Fields:    
  52. Liu CL, Santos MM, Fernandes C, Liao M, Iamarene K, Zhang JY, Sukhova GK, Shi GP. Toll-like receptor 7 deficiency protects apolipoprotein E-deficient mice from diet-induced atherosclerosis. Sci Rep. 2017 04 12; 7(1):847. PMID: 28405010.
    Citations: 6     Fields:    Translation:AnimalsCells
  53. Wang QX, Xue SF, Chen ZH, Ma SH, Zhang S, Shi G, Zhang M. Dual lanthanide-doped complexes: the development of a time-resolved ratiometric fluorescent probe for anthrax biomarker and a paper-based visual sensor. Biosens Bioelectron. 2017 Aug 15; 94:388-393. PMID: 28324858.
    Citations: 9     Fields:    Translation:Humans
  54. Zhou Y, Chen H, Liu L, Yu X, Sukhova GK, Yang M, Zhang L, Kyttaris VC, Tsokos GC, Stillman IE, Ichimura T, Bonventre JV, Libby P, Shi GP. CD74 Deficiency Mitigates Systemic Lupus Erythematosus-like Autoimmunity and Pathological Findings in Mice. J Immunol. 2017 04 01; 198(7):2568-2577. PMID: 28219888.
    Citations: 2     Fields:    Translation:AnimalsCells
  55. Zhou Y, Chen H, Liu L, Yu X, Sukhova GK, Yang M, Kyttaris VC, Stillman IE, Gelb B, Libby P, Tsokos GC, Shi GP. Cathepsin K Deficiency Ameliorates Systemic Lupus Erythematosus-like Manifestations in Faslpr Mice. J Immunol. 2017 03 01; 198(5):1846-1854. PMID: 28093526.
    Citations: 6     Fields:    Translation:AnimalsCells
  56. Shi GP, Bot I, Kovanen PT. Reply: The complexity of substance P-mediated mast cell activation. Nat Rev Cardiol. 2017 02; 14(2):124. PMID: 28054578.
    Citations: 2     Fields:    Translation:HumansCells
  57. Yan X, Wu C, Chen T, Santos MM, Liu CL, Yang C, Zhang L, Ren J, Liao S, Guo H, Sukhova GK, Shi GP. Cathepsin S inhibition changes regulatory T-cell activity in regulating bladder cancer and immune cell proliferation and apoptosis. Mol Immunol. 2017 02; 82:66-74. PMID: 28033540.
    Citations: 5     Fields:    Translation:AnimalsCells
  58. Satyam A, Kannan L, Matsumoto N, Geha M, Lapchak PH, Bosse R, Shi GP, Dalle Lucca JJ, Tsokos MG, Tsokos GC. Intracellular Activation of Complement 3 Is Responsible for Intestinal Tissue Damage during Mesenteric Ischemia. J Immunol. 2017 01 15; 198(2):788-797. PMID: 27913632.
    Citations: 24     Fields:    Translation:HumansAnimalsCells
  59. Donners MM, Bai L, Lutgens SP, Wijnands E, Johnson J, Schurgers LJ, Liu CL, Daemen MJ, Cleutjens KB, Shi GP, Biessen EA, Heeneman S. Cathepsin K Deficiency Prevents the Aggravated Vascular Remodeling Response to Flow Cessation in ApoE-/- Mice. PLoS One. 2016; 11(9):e0162595. PMID: 27636705.
    Citations: 3     Fields:    Translation:AnimalsCells
  60. Wu H, Cheng XW, Hu L, Takeshita K, Hu C, Du Q, Li X, Zhu E, Huang Z, Yisireyili M, Zhao G, Piao L, Inoue A, Jiang H, Lei Y, Zhang X, Liu S, Dai Q, Kuzuya M, Shi GP, Murohara T. Cathepsin S Activity Controls Injury-Related Vascular Repair in Mice via the TLR2-Mediated p38MAPK and PI3K-Akt/p-HDAC6 Signaling Pathway. Arterioscler Thromb Vasc Biol. 2016 08; 36(8):1549-57. PMID: 27365406.
    Citations: 18     Fields:    Translation:AnimalsCells
  61. Xue SF, Lu LF, Wang QX, Zhang S, Zhang M, Shi G. An integrated logic system for time-resolved fluorescent "turn-on" detection of cysteine and histidine base on terbium (III) coordination polymer-copper (II) ensemble. Talanta. 2016 Sep 01; 158:208-213. PMID: 27343597.
    Citations:    Fields:    Translation:Animals
  62. Yang D, Jin C, Ma H, Huang M, Shi GP, Wang J, Xiang M. EphrinB2/EphB4 pathway in postnatal angiogenesis: a potential therapeutic target for ischemic cardiovascular disease. Angiogenesis. 2016 07; 19(3):297-309. PMID: 27216867.
    Citations: 11     Fields:    Translation:HumansAnimalsCells
  63. Zhang C, van der Voort D, Shi H, Zhang R, Qing Y, Hiraoka S, Takemoto M, Yokote K, Moxon JV, Norman P, Rittié L, Kuivaniemi H, Atkins GB, Gerson SL, Shi GP, Golledge J, Dong N, Perbal B, Prosdocimo DA, Lin Z. Matricellular protein CCN3 mitigates abdominal aortic aneurysm. J Clin Invest. 2016 05 02; 126(5):2012. PMID: 27135882.
    Citations: 2     Fields:    
  64. Zhang C, van der Voort D, Shi H, Zhang R, Qing Y, Hiraoka S, Takemoto M, Yokote K, Moxon JV, Norman P, Rittié L, Kuivaniemi H, Atkins GB, Gerson SL, Shi GP, Golledge J, Dong N, Perbal B, Prosdocimo DA, Lin Z. Matricellular protein CCN3 mitigates abdominal aortic aneurysm. J Clin Invest. 2016 Apr 01; 126(4):1282-99. PMID: 26974158.
    Citations: 17     Fields:    Translation:HumansAnimalsCells
  65. Liu CL, Wemmelund H, Wang Y, Liao M, Lindholt JS, Johnsen SP, Vestergaard H, Fernandes C, Sukhova GK, Cheng X, Zhang JY, Yang C, Huang X, Daugherty A, Levy BD, Libby P, Shi GP. Asthma Associates With Human Abdominal Aortic Aneurysm and Rupture. Arterioscler Thromb Vasc Biol. 2016 Mar; 36(3):570-8. PMID: 26868210.
    Citations: 8     Fields:    Translation:Humans
  66. Liu CL, Wang Y, Liao M, Santos MM, Fernandes C, Sukhova GK, Zhang JY, Cheng X, Yang C, Huang X, Levy B, Libby P, Wu G, Shi GP. Allergic lung inflammation promotes atherosclerosis in apolipoprotein E-deficient mice. Transl Res. 2016 May; 171:1-16. PMID: 26898714.
    Citations: 1     Fields:    Translation:AnimalsCells
  67. Liu CL, Wang Y, Liao M, Wemmelund H, Ren J, Fernandes C, Zhou Y, Sukhova GK, Lindholt JS, Johnsen SP, Zhang JY, Cheng X, Huang X, Daugherty A, Levy BD, Libby P, Shi GP. Allergic Lung Inflammation Aggravates Angiotensin II-Induced Abdominal Aortic Aneurysms in Mice. Arterioscler Thromb Vasc Biol. 2016 Jan; 36(1):69-77. PMID: 26543094.
    Citations: 15     Fields:    Translation:AnimalsCells
  68. Zhou Y, Yu X, Chen H, Sjöberg S, Roux J, Zhang L, Ivoulsou AH, Bensaid F, Liu CL, Liu J, Tordjman J, Clement K, Lee CH, Hotamisligil GS, Libby P, Shi GP. Leptin Deficiency Shifts Mast Cells toward Anti-Inflammatory Actions and Protects Mice from Obesity and Diabetes by Polarizing M2 Macrophages. Cell Metab. 2015 Dec 01; 22(6):1045-58. PMID: 26481668.
    Citations: 39     Fields:    Translation:HumansAnimalsCells
  69. Liu CL, Zhang JY, Shi GP. Interaction between allergic asthma and atherosclerosis. Transl Res. 2016 08; 174:5-22. PMID: 26608212.
    Citations: 3     Fields:    Translation:HumansCells
  70. Lee YJ, Liu C, Liao M, Sukhova GK, Shirakawa J, Abdennour M, Iamarene K, Andre S, Inouye K, Clement K, Kulkarni RN, Banks AS, Libby P, Shi GP. Deficiency of Fc?R1 Increases Body Weight Gain but Improves Glucose Tolerance in Diet-Induced Obese Mice. Endocrinology. 2015 Nov; 156(11):4047-58. PMID: 26295369.
    Citations:    Fields:    Translation:HumansAnimalsCells
  71. Tang T, Deng J, Zhang M, Shi G, Zhou T. Quantum dot-DNA aptamer conjugates coupled with capillary electrophoresis: A universal strategy for ratiometric detection of organophosphorus pesticides. Talanta. 2016; 146:55-61. PMID: 26695234.
    Citations: 9     Fields:    Translation:Cells
  72. Shi GP, Bot I, Kovanen PT. Mast cells in human and experimental cardiometabolic diseases. Nat Rev Cardiol. 2015 Nov; 12(11):643-58. PMID: 26259935.
    Citations: 24     Fields:    Translation:HumansAnimalsCells
  73. Wang J, Sun C, Gerdes N, Liu C, Liao M, Liu J, Shi MA, He A, Zhou Y, Sukhova GK, Chen H, Cheng XW, Kuzuya M, Murohara T, Zhang J, Cheng X, Jiang M, Shull GE, Rogers S, Yang CL, Ke Q, Jelen S, Bindels R, Ellison DH, Jarolim P, Libby P, Shi GP. Interleukin 18 function in atherosclerosis is mediated by the interleukin 18 receptor and the Na-Cl co-transporter. Nat Med. 2015 Jul; 21(7):820-6. PMID: 26099046.
    Citations: 23     Fields:    Translation:AnimalsCells
  74. Yan X, Zhang M, Chen X, Wei W, Yang R, Yang Y, Gan W, Guo H, Wang Y, Shi GP. Image-guided percutaneous renal cryoablation for stage 1 renal cell carcinoma with high surgical risk. World J Surg Oncol. 2015 Jun 10; 13:200. PMID: 26059547.
    Citations: 3     Fields:    Translation:Humans
  75. Xu J, Lu X, Shi GP. Vasa vasorum in atherosclerosis and clinical significance. Int J Mol Sci. 2015 May 20; 16(5):11574-608. PMID: 26006236.
    Citations: 25     Fields:    Translation:HumansAnimals
  76. Jiang Y, Tang T, Cao Z, Shi G, Zhou T. Determination of three estrogens and bisphenol A by functional ionic liquid dispersive liquid-phase microextraction coupled with ultra-high performance liquid chromatography and ultraviolet detection. J Sep Sci. 2015 Jun; 38(12):2158-66. PMID: 25864862.
    Citations:    Fields:    Translation:Cells
  77. Xia N, Jiao J, Tang TT, Lv BJ, Lu YZ, Wang KJ, Zhu ZF, Mao XB, Nie SF, Wang Q, Tu X, Xiao H, Liao YH, Shi GP, Cheng X. Activated regulatory T-cells attenuate myocardial ischaemia/reperfusion injury through a CD39-dependent mechanism. Clin Sci (Lond). 2015 May 01; 128(10):679-93. PMID: 25558978.
    Citations: 15     Fields:    Translation:AnimalsCells
  78. Liao M, Liu CL, Lv BJ, Zhang JY, Cheng L, Cheng X, Lindholt JS, Rasmussen LM, Shi GP. Plasma cytokine levels and risks of abdominal aortic aneurysms: A population-based prospective cohort study. Ann Med. 2015 May; 47(3):245-52. PMID: 25856542.
    Citations: 4     Fields:    Translation:Humans
  79. Zhou Y, Wu W, Lindholt JS, Sukhova GK, Libby P, Yu X, Shi GP. Regulatory T cells in human and angiotensin II-induced mouse abdominal aortic aneurysms. Cardiovasc Res. 2015 Jul 01; 107(1):98-107. PMID: 25824145.
    Citations: 16     Fields:    Translation:HumansAnimalsCells
  80. Zhu ZF, Tang TT, Dong WY, Li YY, Xia N, Zhang WC, Zhou SF, Yuan J, Liao MY, Li JJ, Jiao J, Nie SF, Wang Q, Tu X, Xu CQ, Liao YH, Shi GP, Cheng X. Defective circulating CD4+LAP+ regulatory T cells in patients with dilated cardiomyopathy. J Leukoc Biol. 2015 Apr; 97(4):797-805. PMID: 25722319.
    Citations: 7     Fields:    Translation:HumansCells
  81. Hua Y, Robinson TJ, Cao Y, Shi GP, Ren J, Nair S. Cathepsin K knockout alleviates aging-induced cardiac dysfunction. Aging Cell. 2015 Jun; 14(3):345-51. PMID: 25692548.
    Citations: 18     Fields:    Translation:AnimalsCells
  82. Yu Y, Sun X, Tang D, Li C, Zhang L, Nie D, Yin X, Shi G. Gelsolin bound ß-amyloid peptides(1-40/1-42): electrochemical evaluation of levels of soluble peptide associated with Alzheimer's disease. Biosens Bioelectron. 2015 Jun 15; 68:115-121. PMID: 25562737.
    Citations: 10     Fields:    Translation:HumansAnimals
  83. Wu H, Cheng XW, Hu L, Hao CN, Hayashi M, Takeshita K, Hamrah MS, Shi GP, Kuzuya M, Murohara T. Renin inhibition reduces atherosclerotic plaque neovessel formation and regresses advanced atherosclerotic plaques. Atherosclerosis. 2014 Dec; 237(2):739-47. PMID: 25463114.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  84. Yu Y, Zhang L, Li C, Sun X, Tang D, Shi G. A method for evaluating the level of soluble ß-amyloid(1-40/1-42) in Alzheimer's disease based on the binding of gelsolin to ß-amyloid peptides. Angew Chem Int Ed Engl. 2014 Nov 17; 53(47):12832-5. PMID: 25244702.
    Citations: 5     Fields:    Translation:AnimalsCells
  85. Bot I, Shi GP, Kovanen PT. Mast cells as effectors in atherosclerosis. Arterioscler Thromb Vasc Biol. 2015 Feb; 35(2):265-71. PMID: 25104798.
    Citations: 20     Fields:    Translation:HumansAnimalsCells
  86. Wang J, Sjöberg S, Tang TT, Oörni K, Wu W, Liu C, Secco B, Tia V, Sukhova GK, Fernandes C, Lesner A, Kovanen PT, Libby P, Cheng X, Shi GP. Cathepsin G activity lowers plasma LDL and reduces atherosclerosis. Biochim Biophys Acta. 2014 Nov; 1842(11):2174-83. PMID: 25092171.
    Citations: 11     Fields:    
  87. Xu J, Shi GP. Vascular wall extracellular matrix proteins and vascular diseases. Biochim Biophys Acta. 2014 Nov; 1842(11):2106-2119. PMID: 25045854.
    Citations: 63     Fields:    
  88. Wang J, Sukhova GK, Liu J, Ozaki K, Lesner A, Libby P, Kovanen PT, Shi GP. Cathepsin G deficiency reduces periaortic calcium chloride injury-induced abdominal aortic aneurysms in mice. J Vasc Surg. 2015 Dec; 62(6):1615-24. PMID: 25037606.
    Citations: 11     Fields:    Translation:HumansAnimalsCells
  89. Wang J, Lindholt JS, Sukhova GK, Shi MA, Xia M, Chen H, Xiang M, He A, Wang Y, Xiong N, Libby P, Wang JA, Shi GP. IgE actions on CD4+ T cells, mast cells, and macrophages participate in the pathogenesis of experimental abdominal aortic aneurysms. EMBO Mol Med. 2014 Jul; 6(7):952-69. PMID: 24963147.
    Citations: 26     Fields:    Translation:HumansAnimalsCells
  90. Zhou SF, Yuan J, Liao MY, Xia N, Tang TT, Li JJ, Jiao J, Dong WY, Nie SF, Zhu ZF, Zhang WC, Lv BJ, Xiao H, Wang Q, Tu X, Liao YH, Shi GP, Cheng X. IL-17A promotes ventricular remodeling after myocardial infarction. J Mol Med (Berl). 2014 Oct; 92(10):1105-16. PMID: 24965614.
    Citations: 18     Fields:    Translation:AnimalsCells
  91. Jiang H, Cheng XW, Shi GP, Hu L, Inoue A, Yamamura Y, Wu H, Takeshita K, Li X, Huang Z, Song H, Asai M, Hao CN, Unno K, Koike T, Oshida Y, Okumura K, Murohara T, Kuzuya M. Cathepsin K-mediated Notch1 activation contributes to neovascularization in response to hypoxia. Nat Commun. 2014 Jun 04; 5:3838. PMID: 24894568.
    Citations: 32     Fields:    Translation:AnimalsCells
  92. Lafarge JC, Pini M, Pelloux V, Orasanu G, Hartmann G, Venteclef N, Sulpice T, Shi GP, Clément K, Guerre-Millo M. Cathepsin S inhibition lowers blood glucose levels in mice. Diabetologia. 2014 Aug; 57(8):1674-83. PMID: 24891017.
    Citations: 7     Fields:    Translation:Animals
  93. Zhou Y, Zhou T, Zhang M, Shi G. A DNA-scaffolded silver nanocluster/Cu²? ensemble as a turn-on fluorescent probe for histidine. Analyst. 2014 Jun 21; 139(12):3122-6. PMID: 24788120.
    Citations: 2     Fields:    
  94. Chen G, Wang X, Severo MS, Sakhon OS, Sohail M, Brown LJ, Sircar M, Snyder GA, Sundberg EJ, Ulland TK, Olivier AK, Andersen JF, Zhou Y, Shi GP, Sutterwala FS, Kotsyfakis M, Pedra JH. The tick salivary protein sialostatin L2 inhibits caspase-1-mediated inflammation during Anaplasma phagocytophilum infection. Infect Immun. 2014 Jun; 82(6):2553-64. PMID: 24686067.
    Citations: 21     Fields:    Translation:AnimalsCells
  95. Fujita M, Cheng XW, Inden Y, Shimano M, Yoshida N, Inoue A, Yamamoto T, Takeshita K, Kyo S, Taguchi N, Shi GP, Kuzuya M, Okumura K, Murohara T. Mechanisms with clinical implications for atrial fibrillation-associated remodeling: cathepsin K expression, regulation, and therapeutic target and biomarker. J Am Heart Assoc. 2013 Dec 16; 2(6):e000503. PMID: 24342995.
    Citations: 11     Fields:    Translation:HumansAnimalsCells
  96. Hu L, Cheng XW, Song H, Inoue A, Jiang H, Li X, Shi GP, Kozawa E, Okumura K, Kuzuya M. Cathepsin K activity controls injury-related vascular repair in mice. Hypertension. 2014 Mar; 63(3):607-15. PMID: 24343118.
    Citations: 15     Fields:    Translation:Animals
  97. Xu N, Zhang YY, Lin Y, Bao B, Zheng L, Shi GP, Liu J. Increased levels of lysosomal cysteinyl cathepsins in human varicose veins: a histology study. Thromb Haemost. 2014 Feb; 111(2):333-44. PMID: 24154706.
    Citations: 4     Fields:    Translation:HumansCells
  98. Zhou Y, Qu ZB, Zeng Y, Zhou T, Shi G. A novel composite of graphene quantum dots and molecularly imprinted polymer for fluorescent detection of paranitrophenol. Biosens Bioelectron. 2014 Feb 15; 52:317-23. PMID: 24080211.
    Citations: 13     Fields:    
  99. Lv BJ, Lindholt JS, Wang J, Cheng X, Shi GP. Plasma levels of cathepsins L, K, and V and risks of abdominal aortic aneurysms: a randomized population-based study. Atherosclerosis. 2013 Sep; 230(1):100-105. PMID: 23958260.
    Citations: 18     Fields:    Translation:Humans
  100. Chen H, Wang J, Xiang MX, Lin Y, He A, Jin CN, Guan J, Sukhova GK, Libby P, Wang JA, Shi GP. Cathepsin S-mediated fibroblast trans-differentiation contributes to left ventricular remodelling after myocardial infarction. Cardiovasc Res. 2013 Oct 01; 100(1):84-94. PMID: 23771947.
    Citations: 21     Fields:    Translation:AnimalsCells
  101. Wang J, Sjöberg S, Tia V, Secco B, Chen H, Yang M, Sukhova GK, Shi GP. Pharmaceutical stabilization of mast cells attenuates experimental atherogenesis in low-density lipoprotein receptor-deficient mice. Atherosclerosis. 2013 Aug; 229(2):304-9. PMID: 23880180.
    Citations: 6     Fields:    Translation:AnimalsCells
  102. Koskinas KC, Sukhova GK, Baker AB, Papafaklis MI, Chatzizisis YS, Coskun AU, Quillard T, Jonas M, Maynard C, Antoniadis AP, Shi GP, Libby P, Edelman ER, Feldman CL, Stone PH. Thin-capped atheromata with reduced collagen content in pigs develop in coronary arterial regions exposed to persistently low endothelial shear stress. Arterioscler Thromb Vasc Biol. 2013 Jul; 33(7):1494-504. PMID: 23640495.
    Citations: 20     Fields:    Translation:AnimalsCells
  103. Shi GP, Lindholt JS. Mast cells in abdominal aortic aneurysms. Curr Vasc Pharmacol. 2013 May; 11(3):314-26. PMID: 22724485.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  104. Hua Y, Xu X, Shi GP, Chicco AJ, Ren J, Nair S. Cathepsin K knockout alleviates pressure overload-induced cardiac hypertrophy. Hypertension. 2013 Jun; 61(6):1184-92. PMID: 23529168.
    Citations: 20     Fields:    Translation:HumansAnimalsCells
  105. Zeng Y, Zhou Y, Kong L, Zhou T, Shi G. A novel composite of SiO2-coated graphene oxide and molecularly imprinted polymers for electrochemical sensing dopamine. Biosens Bioelectron. 2013 Jul 15; 45:25-33. PMID: 23454339.
    Citations: 5     Fields:    Translation:Humans
  106. Qin Y, Cao X, Yang Y, Shi GP. Cysteine protease cathepsins and matrix metalloproteinases in the development of abdominal aortic aneurysms. Future Cardiol. 2013 Jan; 9(1):89-103. PMID: 23259477.
    Citations: 14     Fields:    Translation:HumansAnimals
  107. He A, Shi GP. Mast cell chymase and tryptase as targets for cardiovascular and metabolic diseases. Curr Pharm Des. 2013; 19(6):1114-25. PMID: 23016684.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  108. Shao X, Gu H, Wang Z, Chai X, Tian Y, Shi G. Highly selective electrochemical strategy for monitoring of cerebral Cu2+ based on a carbon Dot-TPEA hybridized surface. Anal Chem. 2013 Jan 02; 85(1):418-25. PMID: 23214718.
    Citations: 4     Fields:    Translation:Animals
  109. Li P, Zhao W, Wang X, Shi G, Zhou T. Stacking and simultaneous determination of estrogens in water samples by CE with electrochemical detection. J Sep Sci. 2013 Jan; 36(2):334-40. PMID: 23255353.
    Citations:    Fields:    
  110. Wang Z, Liu D, Gu H, Zhu A, Tian Y, Shi G. NTA-modified carbon electrode as a general relaying substrate to facilitate electron transfer of SOD: application to in vivo monitoring of O2(-) in a rat brain. Biosens Bioelectron. 2013 May 15; 43:101-7. PMID: 23291216.
    Citations: 2     Fields:    Translation:AnimalsCells
  111. Wang Z, Zhang H, Shen XH, Jin KL, Ye GF, Qiu W, Qian L, Li B, Zhang YH, Shi GP. Immunoglobulin E and mast cell proteases are potential risk factors of impaired fasting glucose and impaired glucose tolerance in humans. Ann Med. 2013 May; 45(3):220-9. PMID: 23110545.
    Citations: 10     Fields:    Translation:HumansCells
  112. Hua Y, Zhang Y, Dolence J, Shi GP, Ren J, Nair S. Cathepsin K knockout mitigates high-fat diet-induced cardiac hypertrophy and contractile dysfunction. Diabetes. 2013 Feb; 62(2):498-509. PMID: 23069627.
    Citations: 33     Fields:    Translation:AnimalsCells
  113. Cheng X, Wang J, Xia N, Yan XX, Tang TT, Chen H, Zhang HJ, Liu J, Kong W, Sjöberg S, Folco E, Libby P, Liao YH, Shi GP. A guanidine-rich regulatory oligodeoxynucleotide improves type-2 diabetes in obese mice by blocking T-cell differentiation. EMBO Mol Med. 2012 Oct; 4(10):1112-25. PMID: 23027613.
    Citations: 5     Fields:    Translation:AnimalsCells
  114. Wang Y, Shi GP. Mast cell chymase and tryptase in abdominal aortic aneurysm formation. Trends Cardiovasc Med. 2012 Aug; 22(6):150-5. PMID: 22902093.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  115. Zhang J, Chen H, Liu L, Sun J, Shi MA, Sukhova GK, Shi GP. Chemokine (C-C motif) receptor 2 mediates mast cell migration to abdominal aortic aneurysm lesions in mice. Cardiovasc Res. 2012 Dec 01; 96(3):543-51. PMID: 22871590.
    Citations: 9     Fields:    Translation:AnimalsCells
  116. Qin Y, Cao X, Guo J, Zhang Y, Pan L, Zhang H, Li H, Tang C, Du J, Shi GP. Deficiency of cathepsin S attenuates angiotensin II-induced abdominal aortic aneurysm formation in apolipoprotein E-deficient mice. Cardiovasc Res. 2012 Dec 01; 96(3):401-10. PMID: 22871592.
    Citations: 36     Fields:    Translation:AnimalsCells
  117. Lv BJ, Lindholt JS, Cheng X, Wang J, Shi GP. Plasma cathepsin S and cystatin C levels and risk of abdominal aortic aneurysm: a randomized population-based study. PLoS One. 2012; 7(7):e41813. PMID: 22844527.
    Citations: 23     Fields:    Translation:Humans
  118. Elmasri H, Ghelfi E, Yu CW, Traphagen S, Cernadas M, Cao H, Shi GP, Plutzky J, Sahin M, Hotamisligil G, Cataltepe S. Endothelial cell-fatty acid binding protein 4 promotes angiogenesis: role of stem cell factor/c-kit pathway. Angiogenesis. 2012 Sep; 15(3):457-68. PMID: 22562362.
    Citations: 36     Fields:    Translation:HumansAnimalsCells
  119. Cheng XW, Shi GP, Kuzuya M, Sasaki T, Okumura K, Murohara T. Role for cysteine protease cathepsins in heart disease: focus on biology and mechanisms with clinical implication. Circulation. 2012 Mar 27; 125(12):1551-62. PMID: 22451605.
    Citations: 50     Fields:    Translation:HumansAnimals
  120. Liu L, Shi GP. CD31: beyond a marker for endothelial cells. Cardiovasc Res. 2012 Apr 01; 94(1):3-5. PMID: 22379038.
    Citations: 26     Fields:    Translation:Animals
  121. Kozawa E, Nishida Y, Cheng XW, Urakawa H, Arai E, Futamura N, Shi GP, Kuzuya M, Hu L, Sasaki T, Ishiguro N. Osteoarthritic change is delayed in a Ctsk-knockout mouse model of osteoarthritis. Arthritis Rheum. 2012 Feb; 64(2):454-64. PMID: 21968827.
    Citations: 22     Fields:    Translation:AnimalsCells
  122. Shi MA, Shi GP. Different roles of mast cells in obesity and diabetes: lessons from experimental animals and humans. Front Immunol. 2012; 3:7. PMID: 22566893.
    Citations: 17     Fields:    
  123. Liao YH, Xia N, Zhou SF, Tang TT, Yan XX, Lv BJ, Nie SF, Wang J, Iwakura Y, Xiao H, Yuan J, Jevallee H, Wei F, Shi GP, Cheng X. Interleukin-17A contributes to myocardial ischemia/reperfusion injury by regulating cardiomyocyte apoptosis and neutrophil infiltration. J Am Coll Cardiol. 2012 Jan 24; 59(4):420-9. PMID: 22261166.
    Citations: 77     Fields:    Translation:AnimalsCells
  124. Xu JM, Shi GP. Emerging role of mast cells and macrophages in cardiovascular and metabolic diseases. Endocr Rev. 2012 Feb; 33(1):71-108. PMID: 22240242.
    Citations: 34     Fields:    Translation:HumansCells
  125. Wang Z, Zhang H, Shen XH, Jin KL, Ye GF, Qian L, Li B, Zhang YH, Shi GP. Immunoglobulin E and mast cell proteases are potential risk factors of human pre-diabetes and diabetes mellitus. PLoS One. 2011; 6(12):e28962. PMID: 22194960.
    Citations: 14     Fields:    Translation:HumansCells
  126. Xia M, Guerra N, Sukhova GK, Yang K, Miller CK, Shi GP, Raulet DH, Xiong N. Immune activation resulting from NKG2D/ligand interaction promotes atherosclerosis. Circulation. 2011 Dec 20; 124(25):2933-43. PMID: 22104546.
    Citations: 23     Fields:    Translation:HumansAnimalsCells
  127. Zhao X, Zhou Y, Song H, Guan L, Zheng G, Jin Z, Shi D, Li Y, Guo Y, Shi GP, Cheng XW. Comparison of bypass surgery with drug-eluting stents in diabetic patients with left main coronary stenosis. Yonsei Med J. 2011 Nov; 52(6):923-32. PMID: 22028155.
    Citations: 1     Fields:    Translation:Humans
  128. Wang J, Shi GP. Mast cell stabilization: novel medication for obesity and diabetes. Diabetes Metab Res Rev. 2011 Nov; 27(8):919-24. PMID: 22069285.
    Citations: 17     Fields:    Translation:AnimalsCells
  129. Sun J, Sukhova GK, Zhang J, Chen H, Sjöberg S, Libby P, Xiang M, Wang J, Peters C, Reinheckel T, Shi GP. Cathepsin L activity is essential to elastase perfusion-induced abdominal aortic aneurysms in mice. Arterioscler Thromb Vasc Biol. 2011 Nov; 31(11):2500-8. PMID: 21868704.
    Citations: 37     Fields:    Translation:AnimalsCells
  130. Tang TT, Zhu ZF, Wang J, Zhang WC, Tu X, Xiao H, Du XL, Xia JH, Dong NG, Su W, Xia N, Yan XX, Nie SF, Liu J, Zhou SF, Yao R, Xie JJ, Jevallee H, Wang X, Liao MY, Shi GP, Fu M, Liao YH, Cheng X. Correction: impaired thymic export and apoptosis contribute to regulatory T-cell defects in patients with chronic heart failure. PLoS One. 2011; 6(9). PMID: 21977222.
    Citations:    
  131. Tang TT, Zhu ZF, Wang J, Zhang WC, Tu X, Xiao H, Du XL, Xia JH, Dong NG, Su W, Xia N, Yan XX, Yan XX, Nie SF, Liu J, Zhou SF, Yao R, Xie JJ, Jevallee H, Wang X, Liao MY, Shi GP, Fu M, Liao YH, Cheng X. Impaired thymic export and apoptosis contribute to regulatory T-cell defects in patients with chronic heart failure. PLoS One. 2011; 6(9):e24272. PMID: 21935395.
    Citations: 9     Fields:    Translation:HumansCells
  132. Yu Y, Sun Q, Liu X, Wu H, Zhou T, Shi G. Size-controllable gold-platinum alloy nanoparticles on nine functionalized ionic-liquid surfaces and their application as electrocatalysts for hydrogen peroxide reduction. Chemistry. 2011 Sep 26; 17(40):11314-23. PMID: 21853478.
    Citations: 3     Fields:    
  133. Wang J, Cheng X, Xiang MX, Alanne-Kinnunen M, Wang JA, Chen H, He A, Sun X, Lin Y, Tang TT, Tu X, Sjöberg S, Sukhova GK, Liao YH, Conrad DH, Yu L, Kawakami T, Kovanen PT, Libby P, Shi GP. IgE stimulates human and mouse arterial cell apoptosis and cytokine expression and promotes atherogenesis in Apoe-/- mice. J Clin Invest. 2011 Sep; 121(9):3564-77. PMID: 21821913.
    Citations: 47     Fields:    Translation:HumansAnimalsCells
  134. Sun J, Sukhova GK, Zhang J, Chen H, Sjöberg S, Libby P, Xia M, Xiong N, Gelb BD, Shi GP. Cathepsin K deficiency reduces elastase perfusion-induced abdominal aortic aneurysms in mice. Arterioscler Thromb Vasc Biol. 2012 Jan; 32(1):15-23. PMID: 21817099.
    Citations: 38     Fields:    Translation:HumansAnimalsCells
  135. Sjöberg S, Shi GP. Cysteine Protease Cathepsins in Atherosclerosis and Abdominal Aortic Aneurysm. Clin Rev Bone Miner Metab. 2011 Jun 01; 9(2):138-147. PMID: 22505840.
    Citations: 7     
  136. Qin Y, Shi GP. Cysteinyl cathepsins and mast cell proteases in the pathogenesis and therapeutics of cardiovascular diseases. Pharmacol Ther. 2011 Sep; 131(3):338-50. PMID: 21605595.
    Citations: 22     Fields:    Translation:HumansAnimalsCells
  137. Zhang J, Sun J, Lindholt JS, Sukhova GK, Sinnamon M, Stevens RL, Adachi R, Libby P, Thompson RW, Shi GP. Mast cell tryptase deficiency attenuates mouse abdominal aortic aneurysm formation. Circ Res. 2011 May 27; 108(11):1316-27. PMID: 21493897.
    Citations: 33     Fields:    Translation:HumansAnimalsCells
  138. Cheng XW, Song H, Sasaki T, Hu L, Inoue A, Bando YK, Shi GP, Kuzuya M, Okumura K, Murohara T. Angiotensin type 1 receptor blocker reduces intimal neovascularization and plaque growth in apolipoprotein E-deficient mice. Hypertension. 2011 May; 57(5):981-9. PMID: 21464389.
    Citations: 24     Fields:    Translation:Animals
  139. Tang TT, Song Y, Ding YJ, Liao YH, Yu X, Du R, Xiao H, Yuan J, Zhou ZH, Liao MY, Yao R, Jevallee H, Shi GP, Cheng X. Atorvastatin upregulates regulatory T cells and reduces clinical disease activity in patients with rheumatoid arthritis. J Lipid Res. 2011 May; 52(5):1023-32. PMID: 21368320.
    Citations: 31     Fields:    Translation:HumansCells
  140. Cheng XW, Kuzuya M, Sasaki T, Inoue A, Hu L, Song H, Huang Z, Li P, Takeshita K, Hirashiki A, Sato K, Shi GP, Okumura K, Murohara T. Inhibition of mineralocorticoid receptor is a renoprotective effect of the 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitor pitavastatin. J Hypertens. 2011 Mar; 29(3):542-52. PMID: 21119529.
    Citations: 12     Fields:    Translation:AnimalsCells
  141. Urbonaviciene G, Shi GP, Urbonavicius S, Henneberg EW, Lindholt JS. Higher cystatin C level predicts long-term mortality in patients with peripheral arterial disease. Atherosclerosis. 2011 Jun; 216(2):440-5. PMID: 21388623.
    Citations: 12     Fields:    Translation:Humans
  142. Chatzizisis YS, Baker AB, Sukhova GK, Koskinas KC, Papafaklis MI, Beigel R, Jonas M, Coskun AU, Stone BV, Maynard C, Shi GP, Libby P, Feldman CL, Edelman ER, Stone PH. Augmented expression and activity of extracellular matrix-degrading enzymes in regions of low endothelial shear stress colocalize with coronary atheromata with thin fibrous caps in pigs. Circulation. 2011 Feb 15; 123(6):621-30. PMID: 21282495.
    Citations: 34     Fields:    Translation:AnimalsCells
  143. Xiang M, Sun J, Lin Y, Zhang J, Chen H, Yang D, Wang J, Shi GP. Usefulness of serum tryptase level as an independent biomarker for coronary plaque instability in a Chinese population. Atherosclerosis. 2011 Apr; 215(2):494-9. PMID: 21324464.
    Citations: 15     Fields:    Translation:Humans
  144. Zhang J, Alcaide P, Liu L, Sun J, He A, Luscinskas FW, Shi GP. Regulation of endothelial cell adhesion molecule expression by mast cells, macrophages, and neutrophils. PLoS One. 2011 Jan 14; 6(1):e14525. PMID: 21264293.
    Citations: 49     Fields:    Translation:AnimalsCells
  145. Zhang J, Shi GP. Mast cells and metabolic syndrome. Biochim Biophys Acta. 2012 Jan; 1822(1):14-20. PMID: 21185370.
    Citations: 27     Fields:    Translation:HumansAnimalsCells
  146. Tang EH, Shvartz E, Shimizu K, Rocha VZ, Zheng C, Fukuda D, Shi GP, Sukhova G, Libby P. Deletion of EP4 on bone marrow-derived cells enhances inflammation and angiotensin II-induced abdominal aortic aneurysm formation. Arterioscler Thromb Vasc Biol. 2011 Feb; 31(2):261-9. PMID: 21088251.
    Citations: 25     Fields:    Translation:AnimalsCells
  147. Yu W, Liu J, Shi MA, Wang J, Xiang M, Kitamoto S, Wang B, Sukhova GK, Murphy GF, Orasanu G, Grubb A, Shi GP. Cystatin C deficiency promotes epidermal dysplasia in K14-HPV16 transgenic mice. PLoS One. 2010 Nov 15; 5(11):e13973. PMID: 21085595.
    Citations: 10     Fields:    Translation:HumansAnimalsCells
  148. Shi MA, Shi GP. Intracellular delivery strategies for microRNAs and potential therapies for human cardiovascular diseases. Sci Signal. 2010 Nov 02; 3(146):pe40. PMID: 21045204.
    Citations: 6     Fields:    Translation:HumansAnimals
  149. Nie D, Li P, Zhang D, Zhou T, Liang Y, Shi G. Simultaneous determination of nitroaromatic compounds in water using capillary electrophoresis with amperometric detection on an electrode modified with a mesoporous nano-structured carbon material. Electrophoresis. 2010 Sep; 31(17):2981-8. PMID: 20836147.
    Citations: 2     Fields:    Translation:PHPublic Health
  150. Tang EH, Shimizu K, Christen T, Rocha VZ, Shvartz E, Tesmenitsky Y, Sukhova G, Shi GP, Libby P. Lack of EP4 receptors on bone marrow-derived cells enhances inflammation in atherosclerotic lesions. Cardiovasc Res. 2011 Jan 01; 89(1):234-43. PMID: 20736236.
    Citations: 21     Fields:    Translation:AnimalsCells
  151. Sun J, Hartvigsen K, Chou MY, Zhang Y, Sukhova GK, Zhang J, Lopez-Ilasaca M, Diehl CJ, Yakov N, Harats D, George J, Witztum JL, Libby P, Ploegh H, Shi GP. Deficiency of antigen-presenting cell invariant chain reduces atherosclerosis in mice. Circulation. 2010 Aug 24; 122(8):808-20. PMID: 20697023.
    Citations: 35     Fields:    Translation:AnimalsCellsPHPublic Health
  152. Cheng XW, Kuzuya M, Kim W, Song H, Hu L, Inoue A, Nakamura K, Di Q, Sasaki T, Tsuzuki M, Shi GP, Okumura K, Murohara T. Exercise training stimulates ischemia-induced neovascularization via phosphatidylinositol 3-kinase/Akt-dependent hypoxia-induced factor-1 alpha reactivation in mice of advanced age. Circulation. 2010 Aug 17; 122(7):707-16. PMID: 20679550.
    Citations: 37     Fields:    Translation:Animals
  153. Nishizawa T, Cheng XW, Jin Z, Obata K, Nagata K, Hirashiki A, Sasaki T, Noda A, Takeshita K, Izawa H, Shi GP, Kuzuya M, Okumura K, Murohara T. Ca(2+) channel blocker benidipine promotes coronary angiogenesis and reduces both left-ventricular diastolic stiffness and mortality in hypertensive rats. J Hypertens. 2010 Jul; 28(7):1515-26. PMID: 20543715.
    Citations: 2     Fields:    Translation:Animals
  154. Schulte S, Sun J, Libby P, Macfarlane L, Sun C, Lopez-Ilasaca M, Shi GP, Sukhova GK. Cystatin C deficiency promotes inflammation in angiotensin II-induced abdominal aortic aneurisms in atherosclerotic mice. Am J Pathol. 2010 Jul; 177(1):456-63. PMID: 20472891.
    Citations: 26     Fields:    Translation:HumansAnimalsCells
  155. Wu G, Chen T, Shahsafaei A, Hu W, Bronson RT, Shi GP, Halperin JA, Aktas H, Qin X. Complement regulator CD59 protects against angiotensin II-induced abdominal aortic aneurysms in mice. Circulation. 2010 Mar 23; 121(11):1338-46. PMID: 20212283.
    Citations: 17     Fields:    Translation:HumansAnimalsCells
  156. Shi GP. Immunomodulation of vascular diseases: atherosclerosis and autoimmunity. Eur J Vasc Endovasc Surg. 2010 Apr; 39(4):485-94. PMID: 20188603.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  157. Lu Z, Lu Z, Zhu Y, Yan Z, Liu X, Yan W, Yan S, Shi GP. Enhanced hypertension prevalence in non-Han Chinese minorities from Xinjiang Province, China. Hypertens Res. 2009 Dec; 32(12):1097-103. PMID: 19779488.
    Citations: 3     Fields:    Translation:Humans
  158. Sun J, Zhang J, Lindholt JS, Sukhova GK, Liu J, He A, Abrink M, Pejler G, Stevens RL, Thompson RW, Ennis TL, Gurish MF, Libby P, Shi GP. Critical role of mast cell chymase in mouse abdominal aortic aneurysm formation. Circulation. 2009 Sep 15; 120(11):973-82. PMID: 19720934.
    Citations: 63     Fields:    Translation:HumansAnimalsCells
  159. Yang Q, Sun Q, Zhou T, Shi G, Jin L. Determination of parathion in vegetables by electrochemical sensor based on molecularly imprinted polyethyleneimine/silica gel films. J Agric Food Chem. 2009 Aug 12; 57(15):6558-63. PMID: 19586029.
    Citations:    Fields:    Translation:Animals
  160. Liu J, Divoux A, Sun J, Zhang J, Clément K, Glickman JN, Sukhova GK, Wolters PJ, Du J, Gorgun CZ, Doria A, Libby P, Blumberg RS, Kahn BB, Hotamisligil GS, Shi GP. Genetic deficiency and pharmacological stabilization of mast cells reduce diet-induced obesity and diabetes in mice. Nat Med. 2009 Aug; 15(8):940-5. PMID: 19633655.
    Citations: 275     Fields:    Translation:HumansAnimalsCells </