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Robert Scott Harris, M.D.

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Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01HL119344 (THOMPSON, BOYD TAYLOR) Jan 1, 2014 - Dec 31, 2018
    NIH/NHLBI
    Use of advanced imaging techniques to improve diagnostic methods for ARDS
    Role: Co-Principal Investigator
  2. R01HL086717 (HARRIS, ROBERT SCOTT) Mar 1, 2008 - Feb 28, 2014
    NIH/NHLBI
    Redistribution of pulmonary perfusion during bronchoconstriction in asthma
    Role: Principal Investigator
  3. K08HL004501 (HARRIS, ROBERT SCOTT) Mar 1, 2001 - Jan 31, 2007
    NIH/NHLBI
    DYNAMICS OF ALVEOLAR RECRUITMENT IN LUNG INJURY
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Motta-Ribeiro GC, Hashimoto S, Winkler T, Baron RM, Grogg K, Paula LFSC, Santos A, Zeng C, Hibbert K, Harris RS, Bajwa E, Vidal Melo MF. Deterioration of Regional Lung Strain and Inflammation during Early Lung Injury. Am J Respir Crit Care Med. 2018 Oct 01; 198(7):891-902. PMID: 29787304.
    Citations:    Fields:    
  2. Kohli P, Staziaki PV, Janjua SA, Addison DA, Hallett TR, Hennessy O, Takx RAP, Lu MT, Fintelmann FJ, Semigran M, Harris RS, Celli BR, Hoffmann U, Neilan TG. The effect of emphysema on readmission and survival among smokers with heart failure. PLoS One. 2018; 13(7):e0201376. PMID: 30059544.
    Citations:    Fields:    Translation:Humans
  3. Cho JL, Ling MF, Adams DC, Faustino L, Islam SA, Afshar R, Griffith JW, Harris RS, Ng A, Radicioni G, Ford AA, Han AK, Xavier R, Kwok WW, Boucher R, Moon JJ, Hamilos DL, Kesimer M, Suter MJ, Medoff BD, Luster AD. Allergic asthma is distinguished by sensitivity of allergen-specific CD4+ T cells and airway structural cells to type 2 inflammation. Sci Transl Med. 2016 10 05; 8(359):359ra132. PMID: 27708065.
    Citations: 2     Fields:    Translation:HumansCells
  4. Johansen T, Winkler T, Kelly VJ, Osorio-Valencia JS, Greenblatt EE, Harris RS, Venegas JG. A method for mapping regional oxygen and CO2 transfer in the lung. Respir Physiol Neurobiol. 2016 Feb 01; 222:29-47. PMID: 26563454.
    Citations: 3     Fields:    Translation:Humans
  5. Harris RS, Fujii-Rios H, Winkler T, Musch G, Vidal Melo MF, Venegas JG. Ventilation defect formation in healthy and asthma subjects is determined by lung inflation. PLoS One. 2012; 7(12):e53216. PMID: 23285270.
    Citations: 8     Fields:    Translation:Humans
  6. Bansal A, Harris RA, DeGrado TR. Choline phosphorylation and regulation of transcription of choline kinase a in hypoxia. J Lipid Res. 2012 Jan; 53(1):149-57. PMID: 22025560.
    Citations: 5     Fields:    Translation:HumansCells
  7. Harris RS, Venegas JG, Wongviriyawong C, Winkler T, Kone M, Musch G, Vidal Melo MF, de Prost N, Hamilos DL, Afshar R, Cho J, Luster AD, Medoff BD. 18F-FDG uptake rate is a biomarker of eosinophilic inflammation and airway response in asthma. J Nucl Med. 2011 Nov; 52(11):1713-20. PMID: 21990575.
    Citations: 13     Fields:    Translation:HumansAnimalsCells
  8. Wongviriyawong C, Winkler T, Harris RS, Venegas JG. Dynamics of tidal volume and ventilation heterogeneity under pressure-controlled ventilation during bronchoconstriction: a simulation study. J Appl Physiol (1985). 2010 Oct; 109(4):1211-8. PMID: 20671035.
    Citations: 3     Fields:    Translation:Humans
  9. de Prost N, Costa EL, Tucci M, Wellman T, Winkler T, Musch G, Harris R, Venegas J, Vidal Melo MF. Influence of alveolar flooding on 18F-FDG kinetics during acute lung injury. Am J Respir Crit Care Med. 2010; 181(Abstracts):A2586.
  10. Harris R, Wongviriyawong C, Winkler T, Venegas J, Kone M, Musch G, Vidal Melo MF, de Prost N, Hamilos D, Afshar R, Cho JL, Luster AD, Medoff BD. PET-CT for evaluation of airway constriction, ventilation-perfusion, and inflammation in asthma subjects following segmental allergen challenge. Am J Respir Crit Care Med. 2010; 181(Abstracts):A5014.
  11. Venegas J, Wongviriyawong C, Winkler T, Kone M, Musch G, Vidal Melo MF, Harris R. Effects of degree of constriction and wall thickness on the distensibility of constricted airways. Am J Respir Crit Care Med. 2010; 181(Abstracts):A3957.
  12. Wongviriyawong C, Harris R, Kone M, Winkler T, Musch G, Vidal Melo MF, Venegas J. Functional effect of heterogeneity in luminal area along individual airways. Am J Respir Crit Care Med. 2010; 181(Abstracts):A5020.
  13. de Prost N, Tucci M, Costa EL, Wellman T, Winkler T, Musch G, Harris RS, Venegas JG, Vidal Melo MF. Effect of maximal alveolar recruitment on regional lung inflammation during mild endotoxemic acute lung injury (ALI) in sheep. Am J Respir Crit Care Med. 2010; 181(Abstracts):A1687.
  14. Wellman TJ, Winkler T, Costa EL, Musch G, Harris RS, Venegas JG, Melo MF. Measurement of regional specific lung volume change using respiratory-gated PET of inhaled 13N-nitrogen. J Nucl Med. 2010 Apr; 51(4):646-53. PMID: 20237036.
    Citations: 14     Fields:    Translation:Animals
  15. Costa EL, Musch G, Winkler T, Schroeder T, Harris RS, Jones HA, Venegas JG, Vidal Melo MF. Mild endotoxemia during mechanical ventilation produces spatially heterogeneous pulmonary neutrophilic inflammation in sheep. Anesthesiology. 2010 Mar; 112(3):658-69. PMID: 20179503.
    Citations: 27     Fields:    Translation:AnimalsCells
  16. Vidal Melo MF, Winkler T, Harris RS, Musch G, Greene RE, Venegas JG. Spatial heterogeneity of lung perfusion assessed with (13)N PET as a vascular biomarker in chronic obstructive pulmonary disease. J Nucl Med. 2010 Jan; 51(1):57-65. PMID: 20008987.
    Citations: 20     Fields:    Translation:Humans
  17. Owens RL, Harris RS, Malhotra A. Is the way to man's heart (and lung) through the abdomen? Crit Care. 2009; 13(6):199. PMID: 19909491.
    Citations:    Fields:    Translation:Humans
  18. Harris RS, Winkler T, Musch G, Vidal Melo MF, Schroeder T, Tgavalekos N, Venegas JG. The prone position results in smaller ventilation defects during bronchoconstriction in asthma. J Appl Physiol (1985). 2009 Jul; 107(1):266-74. PMID: 19443742.
    Citations: 12     Fields:    Translation:Humans
  19. Aledia AS, Shelley D, Venegas J, Harris RS, Winkler T, George SC. Effect of methacholine-induced bronchoconstriction on exhaled nitric oxide in mild asthmatics. Am J Respir Crit Care Med. 2009; 179(Abstracts):A5184.
  20. Harris RS, Wongviriyawong C, Kone M, Winkler T, Musch G, Vidal Melo MF, Venegas JG. Paradoxical dilation of central airways after methacholine (MCh) challenge in asthma. Am J Respir Crit Care Med. 2009; 179(Abstracts):A2413.
  21. Caramez MP, Kacmarek RM, Helmy M, Miyoshi E, Malhotra A, Amato MB, Harris RS. A comparison of methods to identify open-lung PEEP. Intensive Care Med. 2009 Apr; 35(4):740-7. PMID: 19183951.
    Citations: 12     Fields:    Translation:Animals
  22. John E. Hodgkin Bartolome R. Celli Gerilynn L. Connors. Pulmonary Rehabilitation: Guidelines to Success. 2009; 95-114.
  23. Hardin CC, Harris RS. Mid-frequency ventilation in acute respiratory distress syndrome: the new wave...length? Respir Care. 2008 Dec; 53(12):1655-6. PMID: 19025696.
    Citations:    Fields:    Translation:Humans
  24. Owens RL, Hess DR, Malhotra A, Venegas JG, Harris RS. Effect of the chest wall on pressure-volume curve analysis of acute respiratory distress syndrome lungs. Crit Care Med. 2008 Nov; 36(11):2980-5. PMID: 18824918.
    Citations: 5     Fields:    Translation:Humans
  25. Schroeder T, Vidal Melo MF, Musch G, Harris RS, Venegas JG, Winkler T. Modeling pulmonary kinetics of 2-deoxy-2-[18F]fluoro-D-glucose during acute lung injury. Acad Radiol. 2008 Jun; 15(6):763-75. PMID: 18486012.
    Citations: 23     Fields:    Translation:Animals
  26. Walls JD, Harris RA, Jameson CJ. Measuring chirality in NMR in the presence of a static electric field. J Chem Phys. 2008 Apr 21; 128(15):154502. PMID: 18433230.
    Citations: 2     Fields:    
  27. Schroeder T, Winkler T, Harris RS, Musch G, Vidal Melo MF, Venegas JG. Modeling of Pulmonary Kinetics of 2-deoxy-2-[18F]fluoro-D-glucose during Acute Lung Injury. Proc Am Thor Soc. 2008; 177(Abstracts):A81.
  28. Mauri T, Schroeder T, Avila M, Schettino I, Musch G, Harris RS, Winkler T, Venegas JG, Vidal Melo MF. Relationship between Regional Tissue Density and Extravascular Lung Water in a Sheep Model of Ventilator-Induced Lung Injury and Endotoxemia. Proc Am Thor Soc. 2008; 177(Abstracts):A371.
  29. Harris RS, Musch G, Vidal Melo MF, Schroeder T, Winkler T, Hoffman EA, Venegas JG. Linking Airway Tree Structure and Function with PET-CT in Asthma. Proc Am Thor Soc. 2008; 177(Abstracts):A563.
  30. Caramez MP, Miyoshi E, Harris RS, Kacmarek RM, Malhotra A. Gas exchange impairment induced by open suctioning in acute respiratory distress syndrome: impact of permissive hypercapnia. Crit Care Med. 2008 Feb; 36(2):560-4. PMID: 18091534.
    Citations:    Fields:    Translation:Animals
  31. Hardin CC, Harris RS. Mid frequency ventilation in acute respiratory distress syndrome: the new wave...length?. Resp Care. 2008; 53(12):1655-1656.
  32. Schroeder T, Vidal Melo MF, Musch G, Harris RS, Venegas JG, Winkler T. Image-derived input function for assessment of 18F-FDG uptake by the inflamed lung. J Nucl Med. 2007 Nov; 48(11):1889-96. PMID: 17942803.
    Citations: 16     Fields:    Translation:HumansAnimals
  33. Musch G, Bellani G, Vidal Melo MF, Harris RS, Winkler T, Schroeder T, Venegas JG. Relation between shunt, aeration, and perfusion in experimental acute lung injury. Am J Respir Crit Care Med. 2008 Feb 01; 177(3):292-300. PMID: 17932380.
    Citations: 15     Fields:    Translation:Animals
  34. Schroeder T, Vidal Melo MF, Musch G, Harris RS, Winkler T, Venegas JG. PET Imaging of Regional 18F-FDG Uptake and Lung Function following Cigarette Smoke Inhalation. Proc Am Thor Soc. 2007; 175(Abstracts):A921.
  35. Musch G, Venegas JG, Bellani G, Winkler T, Schroeder T, Petersen B, Harris RS, Melo MF. Regional gas exchange and cellular metabolic activity in ventilator-induced lung injury. Anesthesiology. 2007 Apr; 106(4):723-35. PMID: 17413910.
    Citations: 36     Fields:    Translation:Animals
  36. Arikawa E, Ma RC, Isshiki K, Luptak I, He Z, Yasuda Y, Maeno Y, Patti ME, Weir GC, Harris RA, Zammit VA, Tian R, King GL. Effects of insulin replacements, inhibitors of angiotensin, and PKCbeta's actions to normalize cardiac gene expression and fuel metabolism in diabetic rats. Diabetes. 2007 May; 56(5):1410-20. PMID: 17363743.
    Citations: 24     Fields:    Translation:AnimalsCells
  37. Tgavalekos NT, Musch G, Harris RS, Vidal Melo MF, Winkler T, Schroeder T, Callahan R, Lutchen KR, Venegas JG. Relationship between airway narrowing, patchy ventilation and lung mechanics in asthmatics. Eur Respir J. 2007 Jun; 29(6):1174-81. PMID: 17360726.
    Citations: 24     Fields:    Translation:Humans
  38. Schroeder T, Vidal Melo MF, Musch G, Harris RS, Winkler T, Venegas JG. PET imaging of regional 18F-FDG uptake and lung function after cigarette smoke inhalation. J Nucl Med. 2007 Mar; 48(3):413-9. PMID: 17332619.
    Citations: 16     Fields:    Translation:AnimalsPHPublic Health
  39. Harris RS, Schuster DP. Visualizing lung function with positron emission tomography. J Appl Physiol (1985). 2007 Jan; 102(1):448-58. PMID: 17038490.
    Citations: 17     Fields:    Translation:HumansAnimals
  40. Cho MH, Malhotra A, Donahue DM, Wain JC, Harris RS, Karmpaliotis D, Patel SR. Mechanical ventilation and air leaks after lung biopsy for acute respiratory distress syndrome. Ann Thorac Surg. 2006 Jul; 82(1):261-6. PMID: 16798226.
    Citations: 7     Fields:    Translation:Humans
  41. Harris RS, Lazar O, Johansen JW, Sebel PS. Interaction of propofol and sevoflurane on loss of consciousness and movement to skin incision during general anesthesia. Anesthesiology. 2006 Jun; 104(6):1170-5. PMID: 16732087.
    Citations: 5     Fields:    Translation:Humans
  42. Harris RS, Winkler T, Tgavalekos N, Musch G, Melo MF, Schroeder T, Chang Y, Venegas JG. Regional pulmonary perfusion, inflation, and ventilation defects in bronchoconstricted patients with asthma. Am J Respir Crit Care Med. 2006 Aug 01; 174(3):245-53. PMID: 16690973.
    Citations: 34     Fields:    Translation:Humans
  43. Caramez MP, Schettino G, Suchodolski K, Nishida T, Harris RS, Malhotra A, Kacmarek RM. The impact of endotracheal suctioning on gas exchange and hemodynamics during lung-protective ventilation in acute respiratory distress syndrome. Respir Care. 2006 May; 51(5):497-502. PMID: 16638159.
    Citations: 4     Fields:    Translation:Animals
  44. Ferreira JC, Harris RS, Rocha MJJ, Salge JM, Malhotra A, Kairalla RA, Kacmarek R, Carvalho CRR. A sigmoidal model best predicts the pressure-volume curves of patients with idiopathic pulmonary fibrosis (IPF). Proc Am Thor Soc. 2006; 3(Abstracts):A104.
  45. Venegas JG, Vidal Melo MF, Schroeder T, Winkler T, Musch G, Harris RS. Regional effectiveness of deep inhalations (DI's) in re-opening ventilation defects on bronchoconstricted asthmatic and normal subjects. Proc Am Thor Soc. 2006; 2(Abstracts):A455.
  46. Schroeder T, Winkler T, Vidal Melo MF, Harris RS, Musch G, Tgavalekos NT, Venegas JG. Reproducibility of ventilation defects and heterogeneity in bronchoconstricted asthmatics and normals. Proc Am Thor Soc. 2006; 2(Abstracts):A453.
  47. Winkler T, Harris RS, Tgavalekos NT, Musch G, Vidal Melo MF, Schroeder T, Venegas JG. Ventilation defects during bronchoconstriction in subjects with and without asthma. Proc Am Thor Soc. 2006; 2(Abstracts):A453.
  48. Harris RS, Winkler T, Vidal Melo MF, Musch G, Schroeder T, Tgavalekos N, Lutchen KR, Venegas JG. Body posture and regional bronchoconstriction after methacholine brochoprovocation in asthmatics. Proc Am Thor Soc. 2006; 2(Abstracts):A454.
  49. Venegas JG, Schroeder T, Harris S, Winkler RT, Melo MF. The distribution of ventilation during bronchoconstriction is patchy and bimodal: a PET imaging study. Respir Physiol Neurobiol. 2005 Aug 25; 148(1-2):57-64. PMID: 15994134.
    Citations: 28     Fields:    Translation:Animals
  50. Tgavalekos NT, Tawhai M, Harris RS, Musch G, Mush G, Vidal-Melo M, Venegas JG, Lutchen KR. Identifying airways responsible for heterogeneous ventilation and mechanical dysfunction in asthma: an image functional modeling approach. J Appl Physiol (1985). 2005 Dec; 99(6):2388-97. PMID: 16081622.
    Citations: 42     Fields:    Translation:HumansCTClinical Trials
  51. Richter T, Bellani G, Scott Harris R, Vidal Melo MF, Winkler T, Venegas JG, Musch G. Effect of prone position on regional shunt, aeration, and perfusion in experimental acute lung injury. Am J Respir Crit Care Med. 2005 Aug 15; 172(4):480-7. PMID: 15901611.
    Citations: 31     Fields:    Translation:Animals
  52. Tgavalekos NT, Venegas JG, Harris RS, Lutchen KR. Which airways are most responsible for mechanical and ventilation defects in bronchoconstricted asthmatics?. Proc Am Thor Soc. 2005; 2(Abstracts):A511.
  53. Harris RS, Tgavalekos NT, Winkler T, Musch G, Vidal Melo MF, Bellani G, Schroder T, Venegas JG. Effect of position on the distribution of bronchoconstriction in asthmatics. Proc Am Thor Soc. 2005; (Abstracts):A334.
  54. Venegas J, Tgavalekos N, Vidal Melo MF, Musch G, Winkler T, Harris RS. The distribution of ventilation in broncho-constricted asthmatics and normals is bimodal. Proc Am Thor Soc. 2005; 2(Abstracts):A511.
  55. Schroder T, Vidal Melo MF, Winkler T, Bellani G, Harris RS, Musch G, Venegas JG. Topographical mapping of neutrophil activity during VILI using PET. Proc Am Thor Soc. 2005; 2(Abstracts):A333.
  56. Bellani G, Musch G, Richter T, Vidal Melo MF, Harris RS, Winkler T, Venegas JG. Prone position improves VQ matching in experimental acute lung injury (ALI). Proc Am Thor Society. 2005; 2(Abstracts):A334.
  57. Venegas JG, Winkler T, Musch G, Vidal Melo MF, Layfield D, Tgavalekos N, Fischman AJ, Callahan RJ, Bellani G, Harris RS. Self-organized patchiness in asthma as a prelude to catastrophic shifts. Nature. 2005 Apr 07; 434(7034):777-82. PMID: 15772676.
    Citations: 115     Fields:    Translation:Humans
  58. Melo MF, Harris RS, Layfield JD, Venegas JG. Topographic basis of bimodal ventilation-perfusion distributions during bronchoconstriction in sheep. Am J Respir Crit Care Med. 2005 Apr 01; 171(7):714-21. PMID: 15640360.
    Citations: 11     Fields:    Translation:Animals
  59. Harris RS. Pressure-volume curves of the respiratory system. Respir Care. 2005 Jan; 50(1):78-98; discussion 98-9. PMID: 15636647.
    Citations: 30     Fields:    Translation:Humans
  60. Harris, RS. Invited commentary on "Ventilator-associated lung injury in patients without acute lung injury at the onset of mechanical ventilation" @ Respiratory Failure and Mechanical Ventilation, Journal Club of the Assembly on Critical Care of the American Thoracic Society. www.thoracic.org/assemblies/cc/ccjcframe.html. 2004.
  61. Harris RS, Hadian M, Hess DR, Chang Y, Venegas JG. Pulmonary artery occlusion increases the ratio of diffusing capacity for nitric oxide to carbon monoxide in prone sheep. Chest. 2004 Aug; 126(2):559-65. PMID: 15302745.
    Citations: 1     Fields:    Translation:Animals
  62. Bellani G, Winkler T, Richter T, Musch G, Vidal Melo MF, Harris RS, Venegas JG. Lung gas volumes measured by emission and transmission scans in experimental ALI. Am J Resp Crit Care Med. 2004; 169(7):A548.
  63. El Masry AA, Caramez MP, Miyoshi E, Vargas SO, Shimaoka M, Harris RS, Malhotra A, Kacmarek RM. Sighing versus CPAP for lung recruitment in a sheep ARDS model. Am J Resp Crit Care Med. 2004; 169(7):A719.
  64. Vidal Melo MF, Harris RS, Musch G, Winkler T, Venegas JG. Neutrophil postmigrational activity in a unilateral model of ventilator induced lung injury (VILI) measured with positron emission tomography (PET). Am J Resp Crit Care Med. 2004; 169(7):A351.
  65. Venegas J, Tgavalekos N, Vidal Melo M, Musch G, Bellani G, Winkler T, Harris RS. The distribution of ventilation in bronchoconstricted asthmatics and normals is bimodal. Am J Resp Crit Care Med. 2004; 2:A511.
  66. Harris RS, Tgavalekos NT, Winkler T, Musch G, Vidal Melo MF, Bellani G, Schroder T, Venegas JG. Effect of position on the distribution of bronchoconstriction in asthmatics. Am J Resp Crit Care Med. 2004; 2:A334.
  67. Tgavalekos NT, Harris RS, Vidal Melo MF, Musch G, Winkler T, Venegas JG, Lutchen KR. Identifying airways associated with hyper-reactivity in asthma: Interfacing PET imaging and dyanamic mechanical function with 3D airway models. Am J Resp Crit Care Med. 2004; 169(7):A183.
  68. Schroder T, Vidal Melo MF, Winkler T, Bellani G, Harris RS, Musch G, Venegas JG. Topographical mapping of neutrophil activity during VILI using PET. Am J Resp Crit Care Med. 2004; 2:A333.
  69. Harris RS, Isasi AG, Musch G, Winkler T, Vidal Melo MF, Tgavalekos N, Bellani G, Venegas JG. Imaging aerosol deposition in normal and asthmatic subjects with positron emission tomography. Am J Resp Crit Care Med. 2004; 169(7):A545.
  70. Caramez MP, El Masry AA, Miyoshi E, Harris RS, Malhotra A, Kacmarek RM. Structural and functional assessment of a decremental PEEP trial post lung recruitment. Am J Resp Crit Care Med. 2004; 169(7):A719.
  71. Tgavalekos NT, Venegas JG, Harris RS, Lutchen KR. Which airways are most responsible for mechanical and ventilation defects in bronchoconstricted asthmatics?. Am J Resp Crit Care Med. 2004; 2:A511.
  72. Musch G, Bellani G, O'Neill KR, Harris RS, Vidal Melo MF, Winkler T, Venegas JG. Functional PET imaging of the effect of PEEP on regional gas exchange in acute lung injury. Am J Resp Crit Care Med. 2004; 169(7):A545.
  73. Miyoshi E, El Masry AA, Caramez MP, Harris RS, Malhotra A, Kacmarek RM. Evaluation of CPAP recruitment maneuver using electrical impedance tomography. Am J Resp Crit Care Med. 2004; 169(7):A719.
  74. Bellani G, Musch G, Richter T, Vidal Melo MF, Harris RS, Winkler T, Venegas JG. Prone position improves VQ matching in experimental acute lung injury (ALI). Am J Resp Crit Care Med. 2004; 2:A334.
  75. Musch G, Harris RS, Vidal Melo MF, O'Neill KR, Layfield JD, Winkler T, Venegas JG. Mechanism by which a sustained inflation can worsen oxygenation in acute lung injury. Anesthesiology. 2004 Feb; 100(2):323-30. PMID: 14739807.
    Citations: 26     Fields:    Translation:Animals
  76. Vidal Melo MF, Layfield D, Harris RS, O'Neill K, Musch G, Richter T, Winkler T, Fischman AJ, Venegas JG. Quantification of regional ventilation-perfusion ratios with PET. J Nucl Med. 2003 Dec; 44(12):1982-91. PMID: 14660725.
    Citations: 41     Fields:    Translation:Animals
  77. Harris, RS. Invited commentary on "Differences in the deflation limb of the pressure-volume curves in acute respiratory distress syndrome from pulmonary and extrapulmonary origin" @ Respiratory Failure and Mechanical Ventilation, Journal Club of the Assembly on Critical Care of the American Thoracic Society. www.thoracic.org/assemblies/cc/ccjcframe.html. 2003.
  78. Harris, RS. Invited commentary on “Positive end-expiratory pressure after a recruitment maneuver prevents both alveolar collapse and recruitment/derecruitment” @ Respiratory Failure and Mechanical Ventilation, Journal Club of the Assembly on Critical Care of the American Thoracic Society. www.thoracic.org/assemblies/cc/ccjcframe.html. 2003.
  79. O'Neill K, Venegas JG, Richter T, Harris RS, Layfield JD, Musch G, Winkler T, Melo MF. Modeling kinetics of infused 13NN-saline in acute lung injury. J Appl Physiol (1985). 2003 Dec; 95(6):2471-84. PMID: 12897030.
    Citations: 14     Fields:    Translation:Animals
  80. Harris, RS. Invited commentary on “One-year outcomes in survivors of the acute respiratory distress syndrome” @ Respiratory Failure and Mechanical Ventilation, Journal Club of the Assembly on Critical Care of the American Thoracic Society. www.thoracic.org/assemblies/cc/ccjcframe.html. 2003.
  81. Richter T, Harris RS, Vidal Melo MF, Musch G, Layfield JDH, Winkler T, Ragaller M, Venegas JG . Effects of vaporized perfluorohexane on regional pulmonary perfusion and ventilation in surfactant depleted sheep. Am J Resp Crit Care Med. 2003; 167(7):A179.
  82. Venegas JG, O’Neill K, Fischman A, Harris RS, Musch G, Vidal Melo MF . Lung inflammatory response to cigarette smoking measured by positron emission tomography (PET). Am J Resp Crit Care Med. 2003; 167(7):A874.
  83. Winkler T, Harris RS, Musch G, Layfield JDH, Vidal Melo MF, Venegas JG. Significant changes of pulmonary blood flow in bronchoconstricted asthmatics occur at large length scales. Am J Resp Crit Care Med. 2003; 167(7):A423.
  84. Musch G, Harris RS, Vidal Melo MF, O’Neill K, Layfield JDH, Venegas JG . Mechanism by which a “recruitment maneuver” (RM) can worsen oxygenation in acute lung injury. Am J Resp Crit Care Med. 2003; 167(7):A908.
  85. O’Neill K, Vidal Melo MF, Richter T, Harris RS, Layfield JDH, Musch G, Winkler T, Venegas JG . Modeling arterial kinetics of infused 13NN in acute lung injury. Am J Resp Crit Care Med. 2003; 167(7):A422.
  86. Vidal Melo MF, Harris RS, Musch G, Winkler T, Layfield JDH, Venegas JG. Heterogeneity of regional pulmonary perfusion and ventilation in COPD patients measured with positron emission tomography (PET). Am J Resp Crit Care Med. 2003; 167(7):A80.
  87. Tgavalekos NT, Harris RS, Vidal Melo MF, Musch G, Layfield JDH, Lutchen KR, Venegas JG . Correlation of lung mechanics and ventilation with positron emission tomography during bronchoconstriction. Am J Resp Crit Care Med. 2003; 167(7):A847.
  88. Harris RS, Musch G, Winkler T, Vidal Melo MF, Layfield JDH, Tgavalekos N, Lutchen K, Venegas JG. Imaging of hypoxic pulmonary vasoconstriction (HPV) in asthmatic subjects during bronchoconstriction. Am J Resp Crit Care Med. 2003; 167(7):A698.
  89. Harris, RS. Invited commentary on “Noninvasive vs. conventional mechanical ventilation in patients with chronic obstructive pulmonary disease after failure of medical treatment in the ward: a randomized trial” @ Respiratory Failure and Mechanical Ventilation, Journal Club of the Assembly on Critical Care of the American Thoracic Society. www.thoracic.org/assemblies/cc/ccjcframe.html. 2003.
  90. Musch G, Layfield JD, Harris RS, Melo MF, Winkler T, Callahan RJ, Fischman AJ, Venegas JG. Topographical distribution of pulmonary perfusion and ventilation, assessed by PET in supine and prone humans. J Appl Physiol (1985). 2002 Nov; 93(5):1841-51. PMID: 12381773.
    Citations: 54     Fields:    Translation:Humans
  91. Patel SR, Harris RS, Malhotra A. Pulmonary dead space and survival. N Engl J Med. 2002 Sep 12; 347(11):850-2; author reply 850-2. PMID: 12227367.
    Citations:    Fields:    Translation:Humans
  92. Vidal Melo MF, Harris RS, Layfield D, Musch G, Venegas JG. Changes in regional ventilation after autologous blood clot pulmonary embolism. Anesthesiology. 2002 Sep; 97(3):671-81. PMID: 12218535.
    Citations: 20     Fields:    Translation:Animals
  93. Willey-Courand DB, Harris RS, Galletti GG, Hales CA, Fischman A, Venegas JG. Alterations in regional ventilation, perfusion, and shunt after smoke inhalation measured by PET. J Appl Physiol (1985). 2002 Sep; 93(3):1115-22. PMID: 12183509.
    Citations: 6     Fields:    Translation:Animals
  94. Harris, RS. Invited commentary on “Kinetics and reversibility of mechanical ventilation-associated pulmonary and systemic inflammatory response in patients with acute lung injury” @ Respiratory Failure and Mechanical Ventilation, Journal Club of the Assembly on Critical Care of the American Thoracic Society. www.thoracic.org/assemblies/cc/ccjcframe.html. 2002.
  95. Harris, RS. Invited commentary on “Predicting extubation outcome in patients who have successfully completed a spontaneous breathing trial” @ Respiratory Failure and Mechanical Ventilation, Journal Club of the Assembly on Critical Care of the American Thoracic Society. www.thoracic.org/assemblies/cc/ccjcframe.html. 2002.
  96. Richter T, Harris RS, Vidal Melo MF, Musch G, Layfield JDH, Venegas JG . Prone position virtually eliminates regions of shunt in surfactant depleted sheep. Am J Resp Crit Care Med. 2002; 165(8):A784.
  97. Harris RS, Musch G, Layfield JDH, Vidal Melo MF, Venegas JG. Analysis of hypoventilating (HV) regions in asthmatic subjects using positron emission tomography (PET). Am J Resp Crit Care Med. 2002; 165(8):A780.
  98. Vidal Melo MF, Harris RS, Call DM, Layfield JDH, Venegas JG . VA/Q distributions during bronchoconstriction derived form positron emission tomography (PET) data. Am J Resp Crit Care Med. 2002; 165(8):A706.
  99. Layfield D, Harris RS, Musch G, Vidal-Melo M, Venegas JG. Pulmonary functional imaging with positron emission tomography. Aliverti A, Brusasco V, Macklem PT, Pedotti A, eds. Mechanics of Breathing: Pathophysiology, Diagnosis, and Treatment. 2002; 116-128.
  100. O’Neill K, Vidal Melo MF, Richter T, Harris RS, Layfield JDH, Musch G, Winkler T, Venegas JG . Modeling arterial kinetics of infused 13N2 in acute lung injury. Am J Resp Crit Care Med. 2002; 165(8):A252.
  101. Harris RS, Willey-Courand DB, Head CA, Galletti GG, Call DM, Venegas JG. Regional VA, Q, and VA/Q during PLV: effects of nitroprusside and inhaled nitric oxide. J Appl Physiol (1985). 2002 Jan; 92(1):297-312. PMID: 11744673.
    Citations: 6     Fields:    Translation:Animals
  102. Winkler T, Harris RS, Musch G, Layfield JDH, Vidal Melo MF, Venegas JG. Length scale of heterogeneity in pulmonary blood flow (Q) and gas trapping (GT) in bronchoconstricted asthmatics. Am J Resp Crit Care Med. 2002; 165(8):A251.
  103. Harris, RS. Invited commentary on “The production of inflammatory cytokines in ventilator-induced lung injury” @ Respiratory Failure and Mechanical Ventilation, Journal Club of the Assembly on Critical Care of the American Thoracic Society. www.thoracic.org/assemblies/cc/ccjcframe.html. 2001.
  104. Harris RS, Vidal Melo MF, Musch G, Layfield JDH, Hadian M, Venegas JG . Gas trapping (GT) occurs with nebulized inhaled (IH) methacholine (MCh) but not intravenous (IV) methacholine in prone sheep. Am J Resp Crit Care Med. 2001; 163(5):A926.
  105. Harris RS, Hadian M, Venegas JG . Ratio of diffusing capacity for nitric oxide (DLNO) to carbon monoxide (DLCO) is increased during pulmonary artery occlusion. Am J Resp Crit Care Med. 2001; 163(5):A239.
  106. Musch G, Harris RS, Layfield JDH, Vidal Melo MF, Hadian M, Venegas JG. Effect of a sustained inflation on oxygenation and regional pulmonary perfusion in a lavage model of acute lung injury. Am J Resp Crit Care Med. 2001; 163(5):A675.
  107. Harris RS, Mark EJ. Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 17-2001. A 42-year-old man with multiple pulmonary cysts and recurrent respiratory infections. N Engl J Med. 2001; 344:1701-1708.
  108. Layfield JDH, Harris RS, Musch G, Vidal Melo MF, Callahan RJ, Fischman AJ, Lutchen KR, Venegas JG . Measurement of gas-trapping during bronchoconstriction. Am J Resp Crit Care Med. 2001; 163(5):A422.
  109. Musch G, JDH Layfield, RS Harris, MF Vidalmelo, RJ Callahan, AJ Fischman, JG Venegas. Vertical pulmonary perfusion and ventilation gradients in supine and prone humans. Am J Resp Crit Care Med. 2001; 163(5):A920.
  110. Vidal Melo MF, Harris RS, Layfield JDH, Musch G, Hadian M, Venegas JG . Regional ventilation and perfusion during pulmonary embolism studied with PET. Am J Resp Crit Care Med. 2001; 163(5):A915.
  111. Harris, RS. Invited commentary on “Methods of correcting for dynamic intrinsic PEEP (PEEPi,dyn)” @ Respiratory Failure and Mechanical Ventilation, Journal Club of the Assembly on Critical Care of the American Thoracic Society. www.thoracic.org/assemblies/cc/ccjcframe.html. 2000.
  112. Harris, RS. Invited commentary on “The mechanism of improved oxygenation with prone positioning" @ Respiratory Failure and Mechanical Ventilation, Journal Club of the Assembly on Critical Care of the American Thoracic Society. www.thoracic.org/assemblies/cc/ccjcframe.html. 2000.
  113. Medoff BD, Harris RS, Kesselman H, Venegas J, Amato MB, Hess D. Use of recruitment maneuvers and high-positive end-expiratory pressure in a patient with acute respiratory distress syndrome. Crit Care Med. 2000 Apr; 28(4):1210-6. PMID: 10809308.
    Citations: 15     Fields:    Translation:HumansCells
  114. Harris RS, Hess DR, Venegas JG. An objective analysis of the pressure-volume curve in the acute respiratory distress syndrome. Am J Respir Crit Care Med. 2000 Feb; 161(2 Pt 1):432-9. PMID: 10673182.
    Citations: 30     Fields:    Translation:Humans
  115. Layfield JDH, Venegas JG, Harris RS, Call D . Distribution of pulmonary perfusion during high-frequency oscillatory ventilation. Am J Resp Crit Care Med. 2000; 161(3):A48.
  116. Schwartz DR, Harris RS, Williams P, Ciano B, Hess D, Batista J, Thompson BT, Amato M, Kacmarek RM. Optimum PEEP in ARDS with portable CT scan analysis. Am J Resp Crit Care Med. 2000; 161(3):A380.
  117. Harris RS, Call DM, Layfield JDH, Venegas JG. The effect of body position on airway closure and V/Q heterogeneity during bronchoconstriction measured by PET. Am J Resp Crit Care Med. 2000; 161(3):A469.
  118. Call DM, Harris RS, Layfield JDH, Venegas JG . Relative contribution of different length scales to the heterogeneity in pulmonary ventilation during bronchoconstriction. Am J Resp Crit Care Med. 2000; 161(3):A468.
  119. Kwo J, Bigatello LM, Hess D, Harris RS, Hurford WE . Single breath measurement of pulmonary diffusing capacity for nitric oxide (DLNO) and for carbon monoxide (DLCO) in intubated patients. Am J Resp Crit Care Med. 2000; 161(3):A394.
  120. Makiyama A, Gibson L, Harris RS, Venegas JG . Concentration of stress around an atelectatic region: A finite element model. Am J Resp Crit Care Med. 2000; 161(3):A486.
  121. Harris RS, Call D, Galletti GG, Venegas JG . Regional gas trapping during methacholine infusion in mechanically ventilated sheep measured by PET. Am J Resp Crit Care Med. 1999; 159(3):A872.
  122. Harris RS, Hess D, Venegas JG. A comparison of the upper and lower points of maximal curvature (POMCu,POMCl) and inflection points (infl) of the lung pressure-volume (PV) curve to the total respiratory system (TRS) PV curve in ARDS. Am J Resp Crit Care Med. 1999; 159(3):A457.
  123. Venegas JG, Glenny R, Harris RS, Call D, Layfield JDH, Galletti GG. Comparison between microspheres (MS) and PET imaging of pulmonary perfusion (Q) distribution. Am J Resp Crit Care Med. 1999; 159(3):A577.
  124. Head CA, Harris S, Montero-Huerta P, Call D, Galletti GG, Venegas JG. Assessment of 100mM size microemboli by positron emission tomography (PET). Am J Resp Crit Care Med. 1999; 159(3):A455.
  125. Venegas JG, Harris RS, Amato M. Distributions of opening and closing pressures in ARDS patients derived from the pressure-volume (PV) relationship. Am J Resp Crit Care Med. 1999; 159(3):A77.
  126. Harris RS, Willey-Courand DB, Kwo J, Venegas JG . Nitric oxide (NO) uptake in lung lavage (LL) and pulmonary artery occlusion. Am J Resp Crit Care Med. 1999; 159(3):A220.
  127. Harris RS, Hess D, Kwo J, Venegas JG, Bigatello L, Ritz R, Kacmarek R, Johnson D, Hurford W . Decreased PEEP reduces the nitric oxide (NO) diffusing capacity (DLNO) in ARDS patients. Am J Resp Crit Care Med. 1999; 159(3):A379.
  128. Harris RS, Willey-Courand DB, Kwo J, Venegas JG. Pulmonary dead space measured by nitric oxide (NO) in lung lavage (LL) and pulmonary artery occlusion (PAO). Ann Biomed Eng. 1998; 26(Supplement 1):S-48.
  129. Harris RS, Kwo J, Hess D, Johnson DC, Hurford W, Venegas JG. Pulmonary diffusing capacity of nitric oxide (DLNO) in acute respiratory distress syndrome patients. Am J Resp Crit Care Med. 1998; 157(3):A680.
  130. Willey-Courand D, Harris R, Galletti GG, Head C, Venegas J. Partial liquid ventilation (PLV) reduces shunt in the surfactant deficient lung. Am J Resp Crit Care Med. 1998; 157(3):A464.
  131. Willey-Courand D, Harris R, Galletti GG, Hales C, Venegas JG. Alterations of regional ventilation and perfusion after smoke inhalation. Am J Resp Crit Care Med. 1998; 157(3):A367.
  132. Venegas JG, Harris RS, Simon BA. A comprehensive equation for the pulmonary pressure-volume curve. J Appl Physiol (1985). 1998 Jan; 84(1):389-95. PMID: 9451661.
    Citations: 47     Fields:    Translation:HumansAnimalsCTClinical Trials
  133. Harris RS, Willey DB, Head CA, Galletti G, Venegas JG. Effects of pulmonary vasodilation on regional pulmonary perfusion (Qr) and ventilation (sVAr) during partial liquid ventilation (PLV). Am J Resp Crit Care Med. 1998; 157(3):A462.
  134. Harris RS, Hess D, Venegas JG. Relationship of “Pflex” of the pressure-volume curve to the true inflection point of the deflation limb (infd). Am J Resp Crit Care Med. 1998; 157(3):A694.
  135. Venegas JG, Harris RS. A model of the pressure-volume (PV) relationship of the human respiratory system. Ann Biomed Eng. 1998; 26(supplement 1):S-45.
  136. Venegas JG, Glenny R, Harris R, Willey-Courand DB, Head C, Galletti GG. Comparison between microspheres (MS) and PET imaging of pulmonary perfusion (Q) distribution. Ann Biomed Eng. 1998; 26(Supplement 1):S-49.
  137. Harris RS, Thompson BT . Pleural effusions. Lee B, ed. Quick Consult Manual of Evidence-Based Medicine. 1997; 265-294.
  138. Harris RS, Hess D, Venegas JG. An objective method to determine upper and lower inflection points (Pflex) of the pressure-volume (PV) curve in acute respiratory distress syndrome (ARDS) patients. Am J Respir Crit Care Med. 1997; 155(4Part2):A92.
  139. Venegas JG, Harris RS, Simon B. A universal equation for the pulmonary pressure-volume (PV) curve. Am J Resp Crit Care Med. 1997; 155(4Part2):A862.
  140. Harris RS, Willey DB, Head CA, Galletti G, Venegas JG. Effects of pulmonary vasodilation during partial liquid ventilation (PLV). Ann of Biomed Eng. 1997.
  141. Venegas JG, Harris RS, Galleti G, Willey D, Head CA. Partial liquid ventilation (PLV) decreases shunt and not perfusion to dependent lung regions in oleic acid induced ARDS. Am J Resp Crit Care Med. 1997; 155(4Part2):A745.
  142. Willey DB, Harris RS, Head CA, Galleti G, Venegas JG. Relative perfusion, shunt fraction, and ventilation inequalities occurring during oleic acid induced ARDS as measured by PET. Am J Resp Crit Care Med. 1997; 155(4Part2):A907.
  143. Theoharides TC, Harris RS, Weckstein D. Neuroleptic malignant-like syndrome due to cyclobenzaprine? J Clin Psychopharmacol. 1995 Feb; 15(1):79-81. PMID: 7714231.
    Citations:    Fields:    Translation:Humans
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Funded by the NIH/NCATS Clinical and Translational Science Award (CTSA) program, grant number UL1TR001102, and through institutional support from Harvard University, Harvard Medical School, Harvard T.H. Chan School of Public Health, Beth Israel Deaconess Medical Center, Boston Children's Hospital, Brigham and Women's Hospital, Massachusetts General Hospital and the Dana Farber Cancer Institute.