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James M. Hogle, Ph.D.

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Mentoring
Towards a Structural Understanding of Poliovirus Cell Entry
Part Time, 02/01/99 - 06/18/99

Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01GM085578 (HOGLE, JAMES M) Aug 1, 2008 - Jul 31, 2013
    NIH/NIGMS
    Correlative cryo-microscopy: a new approach for characterizing the structure and
    Role: Principal Investigator
  2. R21AI020566 (HOGLE, JAMES M) Apr 1, 2002 - Mar 31, 2003
    NIH/NIAID
    Structual Analysis of Enterovirus Cell Entry Pathways
    Role: Principal Investigator
  3. S10RR007452 (HOGLE, JAMES M) Sep 30, 1992 - Sep 29, 1993
    NIH/NCRR
    SHARED NMR/X-RAY CRYSTALLOGRAPHY SUPERCOMPUTER FACILITY
    Role: Principal Investigator
  4. U01AI033357 (COEN, DONALD M) Aug 1, 1992 - Jul 31, 1995
    NIH/NIAID
    ANTICMV DRUGS VIA MOLECULAR STUDIES OF CMV DRUG TARGETS
    Role: Co-Principal Investigator
  5. U09GM047794 (ALVAREZ-GONZALEZ, RAFAEL) Sep 30, 1991 - Jun 30, 2006
    NIH/NIGMS
    SCIENTIFIC REVIEW AND EVALUATION AWARD
    Role: Co-Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Zhao Z, Zhang M, Hogle JM, Shih WM, Wagner G, Nasr ML. DNA-Corralled Nanodiscs for the Structural and Functional Characterization of Membrane Proteins and Viral Entry. J Am Chem Soc. 2018 Aug 29; 140(34):10639-10643. PMID: 30094995.
    Citations:    Fields:    
  2. Groppelli E, Levy HC, Sun E, Strauss M, Nicol C, Gold S, Zhuang X, Tuthill TJ, Hogle JM, Rowlands DJ. Picornavirus RNA is protected from cleavage by ribonuclease during virion uncoating and transfer across cellular and model membranes. PLoS Pathog. 2017 02; 13(2):e1006197. PMID: 28166307.
    Citations: 1     Fields:    Translation:HumansCells
  3. Strauss M, Schotte L, Karunatilaka KS, Filman DJ, Hogle JM. Cryo-electron Microscopy Structures of Expanded Poliovirus with VHHs Sample the Conformational Repertoire of the Expanded State. J Virol. 2017 Feb 01; 91(3). PMID: 27852863.
    Citations: 5     Fields:    Translation:HumansCells
  4. Lye MF, Wilkie AR, Filman DJ, Hogle JM, Coen DM. Getting to and through the inner nuclear membrane during herpesvirus nuclear egress. Curr Opin Cell Biol. 2017 06; 46:9-16. PMID: 28086162.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  5. Chen H, Coseno M, Ficarro SB, Mansueto MS, Komazin-Meredith G, Boissel S, Filman DJ, Marto JA, Hogle JM, Coen DM. A Small Covalent Allosteric Inhibitor of Human Cytomegalovirus DNA Polymerase Subunit Interactions. ACS Infect Dis. 2017 02 10; 3(2):112-118. PMID: 28183184.
    Citations:    Fields:    Translation:HumansCells
  6. Nasr ML, Baptista D, Strauss M, Sun ZJ, Grigoriu S, Huser S, Plückthun A, Hagn F, Walz T, Hogle JM, Wagner G. Covalently circularized nanodiscs for studying membrane proteins and viral entry. Nat Methods. 2017 01; 14(1):49-52. PMID: 27869813.
    Citations: 13     Fields:    Translation:HumansCells
  7. Strauss M, Schotte L, Thys B, Filman DJ, Hogle JM. Five of Five VHHs Neutralizing Poliovirus Bind the Receptor-Binding Site. J Virol. 2016 Jan 13; 90(7):3496-505. PMID: 26764003; PMCID: PMC4794687.
    Citations: 4     Fields:    Translation:HumansCells
  8. Lye MF, Sharma M, El Omari K, Filman DJ, Schuermann JP, Hogle JM, Coen DM. Unexpected features and mechanism of heterodimer formation of a herpesvirus nuclear egress complex. EMBO J. 2015 Dec 02; 34(23):2937-52. PMID: 26511021; PMCID: PMC4687685.
    Citations: 15     Fields:    Translation:Cells
  9. Leigh KE, Sharma M, Mansueto MS, Boeszoermenyi A, Filman DJ, Hogle JM, Wagner G, Coen DM, Arthanari H. Structure of a herpesvirus nuclear egress complex subunit reveals an interaction groove that is essential for viral replication. Proc Natl Acad Sci U S A. 2015 Jul 21; 112(29):9010-5. PMID: 26150520; PMCID: PMC4517201.
    Citations: 13     Fields:    Translation:HumansAnimalsCells
  10. Schotte L, Thys B, Strauss M, Filman DJ, Rombaut B, Hogle JM. Characterization of Poliovirus Neutralization Escape Mutants of Single-Domain Antibody Fragments (VHHs). Antimicrob Agents Chemother. 2015 Aug; 59(8):4695-706. PMID: 26014941; PMCID: PMC4505203.
    Citations: 3     Fields:    Translation:HumansCells
  11. Strauss M, Filman DJ, Belnap DM, Cheng N, Noel RT, Hogle JM. Nectin-like interactions between poliovirus and its receptor trigger conformational changes associated with cell entry. J Virol. 2015 Apr; 89(8):4143-57. PMID: 25631086; PMCID: PMC4442392.
    Citations: 17     Fields:    Translation:HumansCells
  12. Moustafa IM, Korboukh VK, Arnold JJ, Smidansky ED, Marcotte LL, Gohara DW, Yang X, Sánchez-Farrán MA, Filman D, Maranas JK, Boehr DD, Hogle JM, Colina CM, Cameron CE. Structural dynamics as a contributor to error-prone replication by an RNA-dependent RNA polymerase. J Biol Chem. 2014 Dec 26; 289(52):36229-48. PMID: 25378410.
    Citations: 11     Fields:    Translation:Cells
  13. Sharma M, Bender BJ, Kamil JP, Lye MF, Pesola JM, Reim NI, Hogle JM, Coen DM. Human cytomegalovirus UL97 phosphorylates the viral nuclear egress complex. J Virol. 2015 Jan; 89(1):523-34. PMID: 25339763; PMCID: PMC4301116.
    Citations: 10     Fields:    Translation:HumansCells
  14. Panjwani A, Strauss M, Gold S, Wenham H, Jackson T, Chou JJ, Rowlands DJ, Stonehouse NJ, Hogle JM, Tuthill TJ. Capsid protein VP4 of human rhinovirus induces membrane permeability by the formation of a size-selective multimeric pore. PLoS Pathog. 2014 Aug; 10(8):e1004294. PMID: 25102288; PMCID: PMC4125281.
    Citations: 27     Fields:    Translation:HumansCells
  15. Ma HC, Liu Y, Wang C, Strauss M, Rehage N, Chen YH, Altan-Bonnet N, Hogle J, Wimmer E, Mueller S, Paul AV, Jiang P. An interaction between glutathione and the capsid is required for the morphogenesis of C-cluster enteroviruses. PLoS Pathog. 2014 Apr; 10(4):e1004052. PMID: 24722315; PMCID: PMC3983063.
    Citations: 5     Fields:    Translation:HumansCells
  16. Schotte L, Strauss M, Thys B, Halewyck H, Filman DJ, Bostina M, Hogle JM, Rombaut B. Mechanism of action and capsid-stabilizing properties of VHHs with an in vitro antipolioviral activity. J Virol. 2014 Apr; 88(8):4403-13. PMID: 24501405; PMCID: PMC3993733.
    Citations: 10     Fields:    Translation:HumansCells
  17. Butan C, Filman DJ, Hogle JM. Cryo-electron microscopy reconstruction shows poliovirus 135S particles poised for membrane interaction and RNA release. J Virol. 2014 Feb; 88(3):1758-70. PMID: 24257617; PMCID: PMC3911577.
    Citations: 26     Fields:    Translation:HumansCells
  18. Lin J, Cheng N, Hogle JM, Steven AC, Belnap DM. Conformational shift of a major poliovirus antigen confirmed by immuno-cryogenic electron microscopy. J Immunol. 2013 Jul 15; 191(2):884-91. PMID: 23772035; PMCID: PMC3816737.
    Citations: 6     Fields:    Translation:HumansCells
  19. Strauss M, Levy HC, Bostina M, Filman DJ, Hogle JM. RNA transfer from poliovirus 135S particles across membranes is mediated by long umbilical connectors. J Virol. 2013 Apr; 87(7):3903-14. PMID: 23365424; PMCID: PMC3624230.
    Citations: 19     Fields:    Translation:Cells
  20. Hogle JM. A 3D framework for understanding enterovirus 71. Nat Struct Mol Biol. 2012 Apr 04; 19(4):367-8. PMID: 22472617.
    Citations: 5     Fields:    Translation:HumansCells
  21. Lin J, Lee LY, Roivainen M, Filman DJ, Hogle JM, Belnap DM. Structure of the Fab-labeled "breathing" state of native poliovirus. J Virol. 2012 May; 86(10):5959-62. PMID: 22398295; PMCID: PMC3347258.
    Citations: 21     Fields:    Translation:HumansCells
  22. Lin J, Cheng N, Chow M, Filman DJ, Steven AC, Hogle JM, Belnap DM. An externalized polypeptide partitions between two distinct sites on genome-released poliovirus particles. J Virol. 2011 Oct; 85(19):9974-83. PMID: 21775460; PMCID: PMC3196412.
    Citations: 24     Fields:    Translation:HumansCells
  23. Bostina M, Levy H, Filman DJ, Hogle JM. Poliovirus RNA is released from the capsid near a twofold symmetry axis. J Virol. 2011 Jan; 85(2):776-83. PMID: 20980499; PMCID: PMC3020038.
    Citations: 50     Fields:    Translation:HumansCells
  24. Levy HC, Bostina M, Filman DJ, Hogle JM. Catching a virus in the act of RNA release: a novel poliovirus uncoating intermediate characterized by cryo-electron microscopy. J Virol. 2010 May; 84(9):4426-41. PMID: 20181687; PMCID: PMC2863768.
    Citations: 54     Fields:    Translation:HumansCells
  25. Tuthill TJ, Groppelli E, Hogle JM, Rowlands DJ. Picornaviruses. Curr Top Microbiol Immunol. 2010; 343:43-89. PMID: 20397067.
    Citations: 54     Fields:    Translation:HumansAnimalsCells
  26. Vaughan JC, Brandenburg B, Hogle JM, Zhuang X. Rapid actin-dependent viral motility in live cells. Biophys J. 2009 Sep 16; 97(6):1647-56. PMID: 19751669; PMCID: PMC3297771.
    Citations: 19     Fields:    Translation:HumansCells
  27. Baltz JL, Filman DJ, Ciustea M, Silverman JE, Lautenschlager CL, Coen DM, Ricciardi RP, Hogle JM. The crystal structure of PF-8, the DNA polymerase accessory subunit from Kaposi's sarcoma-associated herpesvirus. J Virol. 2009 Dec; 83(23):12215-28. PMID: 19759157.
    Citations: 4     Fields:    Translation:HumansCells
  28. Sam MD, Evans BT, Coen DM, Hogle JM. Biochemical, biophysical, and mutational analyses of subunit interactions of the human cytomegalovirus nuclear egress complex. J Virol. 2009 Apr; 83(7):2996-3006. PMID: 19153235; PMCID: PMC2655548.
    Citations: 22     Fields:    Translation:HumansCells
  29. Yang JC, Ji J, Hogle JM, Larson DN. Multiplexed plasmonic sensing based on small-dimension nanohole arrays and intensity interrogation. Biosens Bioelectron. 2009 Apr 15; 24(8):2334-8. PMID: 19157848; PMCID: PMC2716172.
    Citations: 7     Fields:    
  30. Yang JC, Ji J, Hogle JM, Larson DN. Metallic nanohole arrays on fluoropolymer substrates as small label-free real-time bioprobes. Nano Lett. 2008 Sep; 8(9):2718-24. PMID: 18710296; PMCID: PMC2662724.
    Citations: 25     Fields:    
  31. Komazin-Meredith G, Petrella RJ, Santos WL, Filman DJ, Hogle JM, Verdine GL, Karplus M, Coen DM. The human cytomegalovirus UL44 C clamp wraps around DNA. Structure. 2008 Aug 06; 16(8):1214-25. PMID: 18682223; PMCID: PMC2878485.
    Citations: 11     Fields:    Translation:HumansCells
  32. Bubeck D, Filman DJ, Kuzmin M, Fuller SD, Hogle JM. Post-imaging fiducial markers aid in the orientation determination of complexes with mixed or unknown symmetry. J Struct Biol. 2008 Jun; 162(3):480-90. PMID: 18442921; PMCID: PMC2483834.
    Citations: 4     Fields:    Translation:HumansCells
  33. Komazin-Meredith G, Santos WL, Filman DJ, Hogle JM, Verdine GL, Coen DM. The positively charged surface of herpes simplex virus UL42 mediates DNA binding. J Biol Chem. 2008 Mar 07; 283(10):6154-61. PMID: 18178550; PMCID: PMC2889492.
    Citations: 12     Fields:    Translation:Cells
  34. Bostina M, Bubeck D, Schwartz C, Nicastro D, Filman DJ, Hogle JM. Single particle cryoelectron tomography characterization of the structure and structural variability of poliovirus-receptor-membrane complex at 30 A resolution. J Struct Biol. 2007 Nov; 160(2):200-10. PMID: 17897840; PMCID: PMC2083572.
    Citations: 13     Fields:    Translation:Cells
  35. Brandenburg B, Lee LY, Lakadamyali M, Rust MJ, Zhuang X, Hogle JM. Imaging poliovirus entry in live cells. PLoS Biol. 2007 Jul; 5(7):e183. PMID: 17622193.
    Citations: 111     Fields:    Translation:HumansCells
  36. Baron MJ, Filman DJ, Prophete GA, Hogle JM, Madoff LC. Identification of a glycosaminoglycan binding region of the alpha C protein that mediates entry of group B Streptococci into host cells. J Biol Chem. 2007 Apr 06; 282(14):10526-36. PMID: 17259175.
    Citations: 16     Fields:    Translation:HumansAnimalsCells
  37. Marcotte LL, Wass AB, Gohara DW, Pathak HB, Arnold JJ, Filman DJ, Cameron CE, Hogle JM. Crystal structure of poliovirus 3CD protein: virally encoded protease and precursor to the RNA-dependent RNA polymerase. J Virol. 2007 Apr; 81(7):3583-96. PMID: 17251299.
    Citations: 48     Fields:    Translation:Cells
  38. Tuthill TJ, Bubeck D, Rowlands DJ, Hogle JM. Characterization of early steps in the poliovirus infection process: receptor-decorated liposomes induce conversion of the virus to membrane-anchored entry-intermediate particles. J Virol. 2006 Jan; 80(1):172-80. PMID: 16352541; PMCID: PMC1317540.
    Citations: 37     Fields:    Translation:HumansCells
  39. Appleton BA, Brooks J, Loregian A, Filman DJ, Coen DM, Hogle JM. Crystal structure of the cytomegalovirus DNA polymerase subunit UL44 in complex with the C terminus from the catalytic subunit. Differences in structure and function relative to unliganded UL44. J Biol Chem. 2006 Feb 24; 281(8):5224-32. PMID: 16371349.
    Citations: 21     Fields:    Translation:HumansCells
  40. Bryant KF, Cox JC, Wang H, Hogle JM, Ellington AD, Coen DM. Binding of herpes simplex virus-1 US11 to specific RNA sequences. Nucleic Acids Res. 2005; 33(19):6090-100. PMID: 16246910; PMCID: PMC1266072.
    Citations: 10     Fields:    Translation:Cells
  41. Robinson MA, Park S, Sun ZY, Silver PA, Wagner G, Hogle JM. Multiple conformations in the ligand-binding site of the yeast nuclear pore-targeting domain of Nup116p. J Biol Chem. 2005 Oct 21; 280(42):35723-32. PMID: 16105837.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  42. Bubeck D, Filman DJ, Hogle JM. Cryo-electron microscopy reconstruction of a poliovirus-receptor-membrane complex. Nat Struct Mol Biol. 2005 Jul; 12(7):615-8. PMID: 15965485; PMCID: PMC1500892.
    Citations: 32     Fields:    Translation:Cells
  43. Bubeck D, Filman DJ, Cheng N, Steven AC, Hogle JM, Belnap DM. The structure of the poliovirus 135S cell entry intermediate at 10-angstrom resolution reveals the location of an externalized polypeptide that binds to membranes. J Virol. 2005 Jun; 79(12):7745-55. PMID: 15919927; PMCID: PMC1143686.
    Citations: 65     Fields:    Translation:Cells
  44. Aupérin TC, Bolduc GR, Baron MJ, Heroux A, Filman DJ, Madoff LC, Hogle JM. Crystal structure of the N-terminal domain of the group B streptococcus alpha C protein. J Biol Chem. 2005 May 06; 280(18):18245-52. PMID: 15753100.
    Citations: 6     Fields:    Translation:HumansCells
  45. Guogas LM, Filman DJ, Hogle JM, Gehrke L. Cofolding organizes alfalfa mosaic virus RNA and coat protein for replication. Science. 2004 Dec 17; 306(5704):2108-11. PMID: 15604410; PMCID: PMC1500904.
    Citations: 13     Fields:    Translation:Cells
  46. Loregian A, Appleton BA, Hogle JM, Coen DM. Specific residues in the connector loop of the human cytomegalovirus DNA polymerase accessory protein UL44 are crucial for interaction with the UL54 catalytic subunit. J Virol. 2004 Sep; 78(17):9084-92. PMID: 15308704; PMCID: PMC506919.
    Citations: 23     Fields:    Translation:HumansCells
  47. Appleton BA, Loregian A, Filman DJ, Coen DM, Hogle JM. The cytomegalovirus DNA polymerase subunit UL44 forms a C clamp-shaped dimer. Mol Cell. 2004 Jul 23; 15(2):233-44. PMID: 15260974.
    Citations: 38     Fields:    Translation:HumansCells
  48. Loregian A, Appleton BA, Hogle JM, Coen DM. Residues of human cytomegalovirus DNA polymerase catalytic subunit UL54 that are necessary and sufficient for interaction with the accessory protein UL44. J Virol. 2004 Jan; 78(1):158-67. PMID: 14671097; PMCID: PMC303418.
    Citations: 24     Fields:    Translation:HumansCells
  49. Hogle JM. Poliovirus cell entry: common structural themes in viral cell entry pathways. Annu Rev Microbiol. 2002; 56:677-702. PMID: 12142481; PMCID: PMC1500891.
    Citations: 106     Fields:    Translation:HumansCells
  50. Joseph-McCarthy D, Tsang SK, Filman DJ, Hogle JM, Karplus M. Use of MCSS to design small targeted libraries: application to picornavirus ligands. J Am Chem Soc. 2001 Dec 26; 123(51):12758-69. PMID: 11749532.
    Citations: 5     Fields:    Translation:Cells
  51. Jia Q, Hogle JM, Hashikawa T, Nomoto A. Molecular genetic analysis of revertants from a poliovirus mutant that is specifically adapted to the mouse spinal cord. J Virol. 2001 Dec; 75(23):11766-72. PMID: 11689657; PMCID: PMC114762.
    Citations:    Fields:    Translation:AnimalsCells
  52. Bitetti-Putzer R, Joseph-McCarthy D, Hogle JM, Karplus M. Functional group placement in protein binding sites: a comparison of GRID and MCSS. J Comput Aided Mol Des. 2001 Oct; 15(10):935-60. PMID: 11918077.
    Citations: 3     Fields:    Translation:Cells
  53. Tsang SK, McDermott BM, Racaniello VR, Hogle JM. Kinetic analysis of the effect of poliovirus receptor on viral uncoating: the receptor as a catalyst. J Virol. 2001 Jun; 75(11):4984-9. PMID: 11333877; PMCID: PMC114901.
    Citations: 29     Fields:    Translation:HumansCells
  54. Miller ST, Hogle JM, Filman DJ. Ab initio phasing of high-symmetry macromolecular complexes: successful phasing of authentic poliovirus data to 3.0 A resolution. J Mol Biol. 2001 Mar 23; 307(2):499-512. PMID: 11254378.
    Citations: 7     Fields:    Translation:Cells
  55. Tsang SK, Cheh J, Isaacs L, Joseph-McCarthy D, Choi SK, Pevear DC, Whitesides GM, Hogle JM. A structurally biased combinatorial approach for discovering new anti-picornaviral compounds. Chem Biol. 2001 Jan; 8(1):33-45. PMID: 11182317.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  56. Weiss VH, McBride AE, Soriano MA, Filman DJ, Silver PA, Hogle JM. The structure and oligomerization of the yeast arginine methyltransferase, Hmt1. Nat Struct Biol. 2000 Dec; 7(12):1165-71. PMID: 11101900.
    Citations: 43     Fields:    Translation:AnimalsCells
  57. Elkin CD, Zuccola HJ, Hogle JM, Joseph-McCarthy D. Computational design of D-peptide inhibitors of hepatitis delta antigen dimerization. J Comput Aided Mol Des. 2000 Nov; 14(8):705-18. PMID: 11131965.
    Citations:    Fields:    Translation:Cells
  58. Huang Y, Hogle JM, Chow M. Is the 135S poliovirus particle an intermediate during cell entry? J Virol. 2000 Sep; 74(18):8757-61. PMID: 10954579; PMCID: PMC116389.
    Citations: 27     Fields:    Translation:AnimalsCells
  59. Moraleda G, Dingle K, Biswas P, Chang J, Zuccola H, Hogle J, Taylor J. Interactions between hepatitis delta virus proteins. J Virol. 2000 Jun; 74(12):5509-15. PMID: 10823856; PMCID: PMC112036.
    Citations: 11     Fields:    Translation:HumansCells
  60. Tsang SK, Danthi P, Chow M, Hogle JM. Stabilization of poliovirus by capsid-binding antiviral drugs is due to entropic effects. J Mol Biol. 2000 Feb 18; 296(2):335-40. PMID: 10669591.
    Citations: 26     Fields:    Translation:Cells
  61. McBride AE, Weiss VH, Kim HK, Hogle JM, Silver PA. Analysis of the yeast arginine methyltransferase Hmt1p/Rmt1p and its in vivo function. Cofactor binding and substrate interactions. J Biol Chem. 2000 Feb 04; 275(5):3128-36. PMID: 10652296.
    Citations: 29     Fields:    Translation:AnimalsCells
  62. Zuccola HJ, Filman DJ, Coen DM, Hogle JM. The crystal structure of an unusual processivity factor, herpes simplex virus UL42, bound to the C terminus of its cognate polymerase. Mol Cell. 2000 Feb; 5(2):267-78. PMID: 10882068.
    Citations: 56     Fields:    Translation:Cells
  63. Belnap DM, Filman DJ, Trus BL, Cheng N, Booy FP, Conway JF, Curry S, Hiremath CN, Tsang SK, Steven AC, Hogle JM. Molecular tectonic model of virus structural transitions: the putative cell entry states of poliovirus. J Virol. 2000 Feb; 74(3):1342-54. PMID: 10627545; PMCID: PMC111469.
    Citations: 84     Fields:    Translation:Cells
  64. Belnap DM, McDermott BM, Filman DJ, Cheng N, Trus BL, Zuccola HJ, Racaniello VR, Hogle JM, Steven AC. Three-dimensional structure of poliovirus receptor bound to poliovirus. Proc Natl Acad Sci U S A. 2000 Jan 04; 97(1):73-8. PMID: 10618373; PMCID: PMC26618.
    Citations: 89     Fields:    Translation:Cells
  65. Hindiyeh M, Li QH, Basavappa R, Hogle JM, Chow M. Poliovirus mutants at histidine 195 of VP2 do not cleave VP0 into VP2 and VP4. J Virol. 1999 Nov; 73(11):9072-9. PMID: 10516013; PMCID: PMC112939.
    Citations: 25     Fields:    Translation:HumansCells
  66. Trikha J, Filman DJ, Hogle JM. Crystal structure of a 14 bp RNA duplex with non-symmetrical tandem GxU wobble base pairs. Nucleic Acids Res. 1999 Apr 01; 27(7):1728-39. PMID: 10076005; PMCID: PMC148377.
    Citations: 9     Fields:    Translation:Cells
  67. Huang L, Ishii KK, Zuccola H, Gehring AM, Hwang CB, Hogle J, Coen DM. The enzymological basis for resistance of herpesvirus DNA polymerase mutants to acyclovir: relationship to the structure of alpha-like DNA polymerases. Proc Natl Acad Sci U S A. 1999 Jan 19; 96(2):447-52. PMID: 9892653; PMCID: PMC15156.
    Citations: 13     Fields:    Translation:Cells
  68. Filman DJ, Wien MW, Cunningham JA, Bergelson JM, Hogle JM. Structure determination of echovirus 1. Acta Crystallogr D Biol Crystallogr. 1998 Nov 01; 54(Pt 6 Pt 2):1261-72. PMID: 10089503.
    Citations: 20     Fields:    Translation:HumansCells
  69. Basavappa R, Gómez-Yafal A, Hogle JM. The poliovirus empty capsid specifically recognizes the poliovirus receptor and undergoes some, but not all, of the transitions associated with cell entry. J Virol. 1998 Sep; 72(9):7551-6. PMID: 9696852; PMCID: PMC109999.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  70. Zuccola HJ, Rozzelle JE, Lemon SM, Erickson BW, Hogle JM. Structural basis of the oligomerization of hepatitis delta antigen. Structure. 1998 Jul 15; 6(7):821-30. PMID: 9687364.
    Citations: 22     Fields:    Translation:Cells
  71. Dingle K, Bichko V, Zuccola H, Hogle J, Taylor J. Initiation of hepatitis delta virus genome replication. J Virol. 1998 Jun; 72(6):4783-8. PMID: 9573243; PMCID: PMC110015.
    Citations: 12     Fields:    Translation:HumansCells
  72. Grant RA, Filman DJ, Finkel SE, Kolter R, Hogle JM. The crystal structure of Dps, a ferritin homolog that binds and protects DNA. Nat Struct Biol. 1998 Apr; 5(4):294-303. PMID: 9546221.
    Citations: 117     Fields:    Translation:Cells
  73. Hiremath CN, Filman DJ, Grant RA, Hogle JM. Ligand-induced conformational changes in poliovirus-antiviral drug complexes. Acta Crystallogr D Biol Crystallogr. 1997 Sep 01; 53(Pt 5):558-70. PMID: 15299887.
    Citations: 6     Fields:    
  74. Joseph-McCarthy D, Hogle JM, Karplus M. Use of the multiple copy simultaneous search (MCSS) method to design a new class of picornavirus capsid binding drugs. Proteins. 1997 Sep; 29(1):32-58. PMID: 9294865.
    Citations: 7     Fields:    Translation:Cells
  75. Wien MW, Curry S, Filman DJ, Hogle JM. Structural studies of poliovirus mutants that overcome receptor defects. Nat Struct Biol. 1997 Aug; 4(8):666-74. PMID: 9253417.
    Citations: 20     Fields:    Translation:Cells
  76. Benson TE, Walsh CT, Hogle JM. X-ray crystal structures of the S229A mutant and wild-type MurB in the presence of the substrate enolpyruvyl-UDP-N-acetylglucosamine at 1.8-A resolution. Biochemistry. 1997 Jan 28; 36(4):806-11. PMID: 9020778.
    Citations: 3     Fields:    Translation:Cells
  77. Curry S, Chow M, Hogle JM. The poliovirus 135S particle is infectious. J Virol. 1996 Oct; 70(10):7125-31. PMID: 8794359; PMCID: PMC190765.
    Citations: 61     Fields:    Translation:HumansAnimalsCells
  78. Wien MW, Chow M, Hogle JM. Poliovirus: new insights from an old paradigm. Structure. 1996 Jul 15; 4(7):763-7. PMID: 8805560.
    Citations: 12     Fields:    Translation:Cells
  79. Jacobson DH, Hogle JM, Filman DJ. A pseudo-cell based approach to efficient crystallographic refinement of viruses. Acta Crystallogr D Biol Crystallogr. 1996 Jul 01; 52(Pt 4):693-711. PMID: 15299633.
    Citations: 4     Fields:    
  80. Miller ST, Hogle JM, Filman DJ. A genetic algorithm for the ab initio phasing of icosahedral viruses. Acta Crystallogr D Biol Crystallogr. 1996 Mar 01; 52(Pt 2):235-51. PMID: 15299696.
    Citations: 1     Fields:    
  81. Lees WJ, Benson TE, Hogle JM, Walsh CT. (E)-enolbutyryl-UDP-N-acetylglucosamine as a mechanistic probe of UDP-N-acetylenolpyruvylglucosamine reductase (MurB). Biochemistry. 1996 Feb 06; 35(5):1342-51. PMID: 8634262.
    Citations: 2     Fields:    Translation:Cells
  82. Benson TE, Walsh CT, Hogle JM. The structure of the substrate-free form of MurB, an essential enzyme for the synthesis of bacterial cell walls. Structure. 1996 Jan 15; 4(1):47-54. PMID: 8805513.
    Citations: 11     Fields:    Translation:Cells
  83. Benson TE, Filman DJ, Walsh CT, Hogle JM. An enzyme-substrate complex involved in bacterial cell wall biosynthesis. Nat Struct Biol. 1995 Aug; 2(8):644-53. PMID: 7552726.
    Citations: 13     Fields:    Translation:Cells
  84. Hiremath CN, Grant RA, Filman DJ, Hogle JM. Binding of the antiviral drug WIN51711 to the sabin strain of type 3 poliovirus: structural comparison with drug binding in rhinovirus 14. Acta Crystallogr D Biol Crystallogr. 1995 Jul 01; 51(Pt 4):473-89. PMID: 15299834.
    Citations: 8     Fields:    
  85. Wien MW, Filman DJ, Stura EA, Guillot S, Delpeyroux F, Crainic R, Hogle JM. Structure of the complex between the Fab fragment of a neutralizing antibody for type 1 poliovirus and its viral epitope. Nat Struct Biol. 1995 Mar; 2(3):232-43. PMID: 7539711.
    Citations: 19     Fields:    Translation:HumansAnimalsCells
  86. Couderc T, Guédo N, Calvez V, Pelletier I, Hogle J, Colbère-Garapin F, Blondel B. Substitutions in the capsids of poliovirus mutants selected in human neuroblastoma cells confer on the Mahoney type 1 strain a phenotype neurovirulent in mice. J Virol. 1994 Dec; 68(12):8386-91. PMID: 7966631; PMCID: PMC237308.
    Citations: 16     Fields:    Translation:HumansAnimalsCells
  87. Basavappa R, Syed R, Flore O, Icenogle JP, Filman DJ, Hogle JM. Role and mechanism of the maturation cleavage of VP0 in poliovirus assembly: structure of the empty capsid assembly intermediate at 2.9 A resolution. Protein Sci. 1994 Oct; 3(10):1651-69. PMID: 7849583; PMCID: PMC2142606.
    Citations: 60     Fields:    Translation:Cells
  88. Grant RA, Hiremath CN, Filman DJ, Syed R, Andries K, Hogle JM. Structures of poliovirus complexes with anti-viral drugs: implications for viral stability and drug design. Curr Biol. 1994 Sep 01; 4(9):784-97. PMID: 7820548.
    Citations: 30     Fields:    Translation:HumansCells
  89. Benson TE, Walsh CT, Hogle JM. Crystallization and preliminary X-ray crystallographic studies of UDP-N-acetylenolpyruvylglucosamine reductase. Protein Sci. 1994 Jul; 3(7):1125-7. PMID: 7920261; PMCID: PMC2142893.
    Citations:    Fields:    Translation:Cells
  90. Li Q, Yafal AG, Lee YM, Hogle J, Chow M. Poliovirus neutralization by antibodies to internal epitopes of VP4 and VP1 results from reversible exposure of these sequences at physiological temperature. J Virol. 1994 Jun; 68(6):3965-70. PMID: 7514682; PMCID: PMC236902.
    Citations: 82     Fields:    Translation:HumansCells
  91. Jarousse N, Fiette L, Grant RA, Hogle JM, McAllister A, Michiels T, Aubert C, Tangy F, Brahic M, Peña Rossi C. Chimeric Theiler's virus with altered tropism for the central nervous system. J Virol. 1994 May; 68(5):2781-6. PMID: 8151749; PMCID: PMC236765.
    Citations: 8     Fields:    Translation:AnimalsCells
  92. Jarousse N, Grant RA, Hogle JM, Zhang L, Senkowski A, Roos RP, Michiels T, Brahic M, McAllister A. A single amino acid change determines persistence of a chimeric Theiler's virus. J Virol. 1994 May; 68(5):3364-8. PMID: 7512164; PMCID: PMC236827.
    Citations: 30     Fields:    Translation:AnimalsCells
  93. Morrison ME, He YJ, Wien MW, Hogle JM, Racaniello VR. Homolog-scanning mutagenesis reveals poliovirus receptor residues important for virus binding and replication. J Virol. 1994 Apr; 68(4):2578-88. PMID: 8139037; PMCID: PMC236735.
    Citations: 29     Fields:    Translation:HumansAnimalsCells
  94. Gómez Yafal A, Kaplan G, Racaniello VR, Hogle JM. Characterization of poliovirus conformational alteration mediated by soluble cell receptors. Virology. 1993 Nov; 197(1):501-5. PMID: 8212594.
    Citations: 39     Fields:    Translation:AnimalsCells
  95. Moscufo N, Yafal AG, Rogove A, Hogle J, Chow M. A mutation in VP4 defines a new step in the late stages of cell entry by poliovirus. J Virol. 1993 Aug; 67(8):5075-8. PMID: 8392631; PMCID: PMC237900.
    Citations: 25     Fields:    Translation:HumansCells
  96. Couderc T, Hogle J, Le Blay H, Horaud F, Blondel B. Molecular characterization of mouse-virulent poliovirus type 1 Mahoney mutants: involvement of residues of polypeptides VP1 and VP2 located on the inner surface of the capsid protein shell. J Virol. 1993 Jul; 67(7):3808-17. PMID: 8389907; PMCID: PMC237745.
    Citations: 19     Fields:    Translation:HumansAnimalsCells
  97. Syed R, Wu ZP, Hogle JM, Hilvert D. Crystal structure of selenosubtilisin at 2.0-A resolution. Biochemistry. 1993 Jun 22; 32(24):6157-64. PMID: 8512925.
    Citations: 8     Fields:    Translation:Cells
  98. Hogle JM. Virus-ligand structures: the viral canyon. Curr Biol. 1993 May 01; 3(5):278-81. PMID: 15335748.
    Citations: 2     Fields:    
  99. Dedieu JF, Ronco J, van der Werf S, Hogle JM, Henin Y, Girard M. Poliovirus chimeras expressing sequences from the principal neutralization domain of human immunodeficiency virus type 1. J Virol. 1992 May; 66(5):3161-7. PMID: 1373205; PMCID: PMC241080.
    Citations: 15     Fields:    Translation:HumansCells
  100. Grant RA, Filman DJ, Fujinami RS, Icenogle JP, Hogle JM. Three-dimensional structure of Theiler virus. Proc Natl Acad Sci U S A. 1992 Mar 15; 89(6):2061-5. PMID: 1549565; PMCID: PMC48596.
    Citations: 35     Fields:    Translation:AnimalsCells
  101. Yeates TO, Jacobson DH, Martin A, Wychowski C, Girard M, Filman DJ, Hogle JM. Three-dimensional structure of a mouse-adapted type 2/type 1 poliovirus chimera. EMBO J. 1991 Sep; 10(9):2331-41. PMID: 1651227; PMCID: PMC452928.
    Citations: 29     Fields:    Translation:AnimalsCells
  102. Filman DJ, Hogle JM. Virology. Architecture with a difference. Nature. 1991 May 09; 351(6322):100-1. PMID: 2030727.
    Citations: 1     Fields:    Translation:Cells
  103. Muir S, Weintraub JP, Hogle J, Bittle JL. Neutralizing antibody to Mengo virus, induced by synthetic peptides. J Gen Virol. 1991 May; 72 ( Pt 5):1087-92. PMID: 1709682.
    Citations: 6     Fields:    Translation:AnimalsCells
  104. Martin A, Benichou D, Couderc T, Hogle JM, Wychowski C, Van der Werf S, Girard M. Use of type 1/type 2 chimeric polioviruses to study determinants of poliovirus type 1 neurovirulence in a mouse model. Virology. 1991 Feb; 180(2):648-58. PMID: 1846492.
    Citations: 20     Fields:    Translation:HumansAnimalsCells
  105. Fricks CE, Hogle JM. Cell-induced conformational change in poliovirus: externalization of the amino terminus of VP1 is responsible for liposome binding. J Virol. 1990 May; 64(5):1934-45. PMID: 2157861; PMCID: PMC249347.
    Citations: 202     Fields:    Translation:HumansCells
  106. Zurbriggen A, Hogle JM, Fujinami RS. Alteration of amino acid 101 within capsid protein VP-1 changes the pathogenicity of Theiler's murine encephalomyelitis virus. J Exp Med. 1989 Dec 01; 170(6):2037-49. PMID: 2479706; PMCID: PMC2189529.
    Citations: 22     Fields:    Translation:Cells
  107. Hogle JM, Filman DJ. The antigenic structure of poliovirus. Philos Trans R Soc Lond B Biol Sci. 1989 Jun 12; 323(1217):467-78. PMID: 2569204.
    Citations: 9     Fields:    Translation:Cells
  108. Filman DJ, Syed R, Chow M, Macadam AJ, Minor PD, Hogle JM. Structural factors that control conformational transitions and serotype specificity in type 3 poliovirus. EMBO J. 1989 May; 8(5):1567-79. PMID: 2548847; PMCID: PMC400988.
    Citations: 110     Fields:    Translation:Cells
  109. Hogle JM, Filman DJ. Poliovirus: three-dimensional structure of a viral antigen. Adv Vet Sci Comp Med. 1989; 33:65-91. PMID: 2539003.
    Citations: 3     Fields:    Translation:Cells
  110. Ypma-Wong MF, Filman DJ, Hogle JM, Semler BL. Structural domains of the poliovirus polyprotein are major determinants for proteolytic cleavage at Gln-Gly pairs. J Biol Chem. 1988 Nov 25; 263(33):17846-56. PMID: 2846581.
    Citations: 29     Fields:    Translation:HumansCells
  111. Martin A, Wychowski C, Couderc T, Crainic R, Hogle J, Girard M. Engineering a poliovirus type 2 antigenic site on a type 1 capsid results in a chimaeric virus which is neurovirulent for mice. EMBO J. 1988 Sep; 7(9):2839-47. PMID: 2460345; PMCID: PMC457076.
    Citations: 64     Fields:    Translation:AnimalsCells
  112. Page GS, Mosser AG, Hogle JM, Filman DJ, Rueckert RR, Chow M. Three-dimensional structure of poliovirus serotype 1 neutralizing determinants. J Virol. 1988 May; 62(5):1781-94. PMID: 2451757; PMCID: PMC253228.
    Citations: 66     Fields:    Translation:HumansCells
  113. Hogle JM. Antigenic hybrids of poliovirus. Nature. 1988 Mar 03; 332(6159):13-4. PMID: 2831454.
    Citations:    Fields:    Translation:HumansCells
  114. Chow M, Newman JF, Filman D, Hogle JM, Rowlands DJ, Brown F. Myristylation of picornavirus capsid protein VP4 and its structural significance. Nature. 1987 Jun 11-17; 327(6122):482-6. PMID: 3035380.
    Citations: 150     Fields:    Translation:Cells
  115. Hogle JM, Chow M, Filman DJ. The structure of poliovirus. Sci Am. 1987 Mar; 256(3):42-9. PMID: 3029862.
    Citations:    Fields:    Translation:Cells
  116. Hogle JM, Maeda A, Harrison SC. Structure and assembly of turnip crinkle virus. I. X-ray crystallographic structure analysis at 3.2 A resolution. J Mol Biol. 1986 Oct 20; 191(4):625-38. PMID: 3806676.
    Citations: 32     Fields:    Translation:Cells
  117. Icenogle JP, Minor PD, Ferguson M, Hogle JM. Modulation of humoral response to a 12-amino-acid site on the poliovirus virion. J Virol. 1986 Oct; 60(1):297-301. PMID: 3018295; PMCID: PMC253930.
    Citations: 23     Fields:    Translation:AnimalsCells
  118. Hogle JM, Chow M, Filman DJ. Three-dimensional structure of poliovirus at 2.9 A resolution. Science. 1985 Sep 27; 229(4720):1358-65. PMID: 2994218.
    Citations: 331     Fields:    Translation:Cells
  119. Fricks CE, Icenogle JP, Hogle JM. Trypsin sensitivity of the Sabin strain of type 1 poliovirus: cleavage sites in virions and related particles. J Virol. 1985 Jun; 54(3):856-9. PMID: 2987536; PMCID: PMC254874.
    Citations: 28     Fields:    Translation:Cells
  120. Chow M, Yabrov R, Bittle J, Hogle J, Baltimore D. Synthetic peptides from four separate regions of the poliovirus type 1 capsid protein VP1 induce neutralizing antibodies. Proc Natl Acad Sci U S A. 1985 Feb; 82(3):910-4. PMID: 2983321; PMCID: PMC397157.
    Citations: 33     Fields:    Translation:AnimalsCells
  121. Hogle J, Kirchhausen T, Harrison SC. Divalent cation sites in tomato bushy stunt virus. Difference maps at 2-9 A resolution. J Mol Biol. 1983 Nov 25; 171(1):95-100. PMID: 6417343.
    Citations: 12     Fields:    Translation:Cells
  122. Niman HL, Houghten RA, Walker LE, Reisfeld RA, Wilson IA, Hogle JM, Lerner RA. Generation of protein-reactive antibodies by short peptides is an event of high frequency: implications for the structural basis of immune recognition. Proc Natl Acad Sci U S A. 1983 Aug; 80(16):4949-53. PMID: 6192445; PMCID: PMC384165.
    Citations: 109     Fields:    Translation:AnimalsCells
  123. Hogle JM. Preliminary studies of crystals of poliovirus type I. J Mol Biol. 1982 Oct 05; 160(4):663-8. PMID: 6294308.
    Citations: 5     Fields:    Translation:Cells
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Funded by the NIH/NCATS Clinical and Translational Science Award (CTSA) program, grant number UL1TR001102, and through institutional support from Harvard University, Harvard Medical School, Harvard T.H. Chan School of Public Health, Beth Israel Deaconess Medical Center, Boston Children's Hospital, Brigham and Women's Hospital, Massachusetts General Hospital and the Dana Farber Cancer Institute.